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A Mechanistic Approach to Medicines for Tuberculosis Nanotherapy

A Mechanistic Approach to Medicines for Tuberculosis Nanotherapy
  • Author : Rajan Mariappan
  • Publisher :Unknown
  • Release Date :2021-03-29
  • Total pages :326
  • ISBN : 9780128244845
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Summary : A Mechanistic Approach to Medicines for Tuberculosis Nanotherapy examines drug carrier development for controlled, targeted, pH and stimuli responsive drug releases for tuberculosis. The book provides in-depth information about mycobacterium tuberculosis, tuberculosis formation, and synthetic procedures for carrier synthesis, characterizations and mechanistic approaches. Key topics include the properties and functions of nanomedicines and how they might be applied for clinical diagnosis and treatment. Emphasis is placed on the basic fundamentals, biomaterial formulations, design principles, fabrication techniques, and transitioning bench-to-bed clinical applications. This book is useful for new researchers who focus on nanomedicine, stem cell therapy and bone tissue engineering. In addition, it introduces experienced researchers and clinicians to key trends, thus increasing their knowledge in drug discovery for tuberculosis and nanomedicine. Features the most notable uses of drug for tuberculosis treatment, including novel advances in materials Assesses new agents and chemical compounds against tuberculosis Examines the interaction of new technologies to discover ways to treat tuberculosis more effectively and efficiently

Nanotechnology Based Approaches for Tuberculosis Treatment

Nanotechnology Based Approaches for Tuberculosis Treatment
  • Author : Prashant Kesharwani
  • Publisher :Unknown
  • Release Date :2020-06-10
  • Total pages :284
  • ISBN : 9780128226117
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Summary : Nanotechnology Based Approaches for Tuberculosis Treatment discusses multiple nanotechnology-based approaches that may help overcome persisting limitations of conventional and traditional treatments. The book summarizes the types of nano drugs, their synthesis, formulation, characterization and applications, along with the most important administration routes. It also explores recent advances and achievements regarding therapeutic efficacy and provides possible future applications in this field. It will be a useful resource for investigators, pharmaceutical researchers, innovators and scientists working on technology advancements in the areas of targeted therapies, nano scale imaging systems, and diagnostic modalities in tuberculosis. Addresses the gap between nanomedicine late discovery and early development of tuberculosis therapeutics Explores tuberculosis nanomedicine standardization and characterization with newly developed treatment, diagnostic and treatment monitoring modalities Covers the field thoroughly, from the pathogenesis of tuberculosis and multi-drug resistant mycobacterium tuberculosis, to treatment approaches using nanotechnology and different nanocarriers

Nanoparticle Drug Delivery Systems for Cancer Treatment

Nanoparticle Drug Delivery Systems for Cancer Treatment
  • Author : Hala Gali-Muhtasib,Racha Chouaib
  • Publisher :Unknown
  • Release Date :2020-02-19
  • Total pages :326
  • ISBN : 9781000681413
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Summary : In recent years, nanoparticles—bionanomaterials with specific physicochemical properties—have gained a great deal of scientific interest owing to their unique structure. Nanoparticle-based drugs are now widely regarded as a safer, more precise, and more effective mode of cancer therapy, considering their ability to enhance drug bioavailability, improve site-specific drug delivery, and protect nontarget tissues from toxic therapeutic drugs. This book compiles and details cutting-edge research in nanomedicine from an interdisciplinary team of international cancer researchers who are currently revolutionizing drug delivery techniques through the development of nanomedicines and nanotheranostics. Edited by Hala Gali-Muhtasib and Racha Chouaib, two prominent cancer researchers, this book will appeal to anyone involved in nanotechnology, cancer therapy, or drug delivery research.

Nanotheranostics for Cancer Applications

Nanotheranostics for Cancer Applications
  • Author : Prakash Rai,Stephanie A. Morris
  • Publisher :Unknown
  • Release Date :2018-11-12
  • Total pages :480
  • ISBN : 9783030017750
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Summary : This book is the first to focus specifically on cancer nanotheranostics. Each of the chapters that make up this comprehensive volume is authored by a researcher, clinician, or regulatory agency member known for their expertise in this field. Theranostics, the technology to simultaneously diagnose and treat a disease, is a nascent field that is growing rapidly in this era of personalized medicine. As the need for cost-effective disease diagnosis grows, drug delivery systems that can act as multifunctional carriers for imaging contrast and therapy agents could provide unique breakthroughs in oncology. Nanotechnology has enabled the development of smart theranostic platforms that can concurrently diagnose disease, start primary treatment, monitor response and initiate secondary treatments if required. In oncology, chemotherapeutics have been routinely used. Some drugs have proven effective but all carry risks of adverse side effects. There is growing interest in using remotely triggered drug delivery systems to limit cytotoxicity in the diseased area. This book reviews the use of theranostic nanoparticles for cancer applications over the past decade. First, it briefly discusses the challenges and limitations of conventional cancer treatments, and presents an overview of the use of nanotechnology in treating cancer. These introductory chapters are followed by those exploring cancer diagnosis and a myriad of delivery methods for nanotherapeutics. The book also addresses multifunctional platforms, treatment monitoring, and regulatory considerations. As a whole, the book aims to briefly summarize the development and clinical potential of various nanotheranostics for cancer applications, and to delineate the challenges that must be overcome for successful clinical development and implementation of such cancer theranostics.

NanoBioMedicine

NanoBioMedicine
  • Author : Shailendra K. Saxena,S. M. Paul Khurana
  • Publisher :Unknown
  • Release Date :2020-02-03
  • Total pages :517
  • ISBN : 9789813298989
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Summary : This book provides a comprehensive overview of the recent trends in various Nanotechnology-based therapeutics and challenges associated with its development. Nanobiotechnology is an interdisciplinary research that has wide applications in the various fields of biomedical research. The book discusses the various facets of the application of Nanotechnology in drug delivery, clinical diagnostics, Nanomedicine and treatment of infectious and chronic diseases. The book also highlights the recent advancements on important devices and applications that are based on Nanotechnology in medicine and brief the regulatory and ethical issues related to nanomedical devices. It also reviews the toxicological profile of various nanomaterials and emphasizes the need for safe nanomaterials for clinical use. Finally, the book discusses the recent developments of potential commercial applications of Nanotechnology.

Multifunctional Nanocarriers for Contemporary Healthcare Applications

Multifunctional Nanocarriers for Contemporary Healthcare Applications
  • Author : Barkat, Md. Abul,A.B., Harshita,Beg, Sarwar,Ahmad, Farhan J.
  • Publisher :Unknown
  • Release Date :2018-01-12
  • Total pages :602
  • ISBN : 9781522547822
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Summary : Advances in technology permeates every aspect of life, including the healthcare system. Nanotechnology based systems have gained popularity based upon their promise, size, and other characteristics. Multifunctional Nanocarriers for Contemporary Healthcare Applications is a critical academic publication that explores advancements in nanostructured systems, applications of these systems in healthcare, and biomedical applications of these systems. Featuring coverage on a wide range of topics, such as hydrogels, controlled drug delivery systems, and nanomedicine, this book is geared toward researchers, students, and academicians seeking current research on advancements and applications of nanostructured systems in the healthcare industry.

Biomedical Applications of Functionalized Nanomaterials

Biomedical Applications of Functionalized Nanomaterials
  • Author : Bruno Sarmento,Jose Das Neves
  • Publisher :Unknown
  • Release Date :2018-03-01
  • Total pages :778
  • ISBN : 9780323508797
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Summary : Biomedical Applications of Functionalized Nanomaterials: Concepts, Development and Clinical Translation presents a concise overview of the most promising nanomaterials functionalized with ligands for biomedical applications. The first section focuses on current strategies for identifying biological targets and screening of ligand to optimize anchoring to nanomaterials, providing the foundation for the remaining parts. Section Two covers specific applications of functionalized nanomaterials in therapy and diagnostics, highlighting current practice and addressing major challenges, in particular, case studies of successfully developed and marketed functionalized nanomaterials. The final section focuses on regulatory issues and clinical translation, providing a legal framework for their use in biomedicine. This book is an important reference source for worldwide drug and medical devices policymakers, biomaterials scientists and regulatory bodies. Provides an overview of the methodologies for biological target identification and ligand screening Includes case studies showing the development of functionalized nanomaterials and their biomedical applications Highlights the importance of functionalized nanomaterials for drug delivery, diagnostics and regenerative medicine applications

Buck's Step-by-Step Medical Coding, 2021 Edition - EBook

Buck's Step-by-Step Medical Coding, 2021 Edition - EBook
  • Author : Elsevier
  • Publisher :Unknown
  • Release Date :2020-11-08
  • Total pages :832
  • ISBN : 9780323777339
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Summary : Theory and practical review questions (located at the end of each chapter) focus on recalling important chapter information and application of codes. A step-by-step approach makes it easier for students to build coding skills and remember the material. Learning objective and glossary review questions reinforce student understanding of key chapter concepts and terms. 30-day trial to TruCode® Encoder Essentials gives students experience with using an encoder (plus access to additional encoder practice exercises on the Evolve website). UNIQUE! "Real-life" coding reports (cleared of any confidential information) simulate the reports students will encounter as coders, and help them apply coding principles to actual cases. Online activities on Evolve provide extra practice with assignments, including coding reports. More than 450 illustrations help in understanding the types of medical conditions and procedures being coded, and include examples taken directly from Elsevier's professional ICD-10 and HCPCS manuals. UNIQUE! Four coding-question variations — covering both single-code questions and multiple-code questions and scenarios — develop students’ coding ability and critical thinking skills. UNIQUE! Coders’ Index in the back of the book makes it easy to quickly locate specific codes. Official Guidelines for Coding and Reporting boxes show the official guidelines wording for inpatient and outpatient coding alongside in-text explanations. Exercises, Quick Checks, and Toolbox features reinforce coding rules and concepts, and emphasize key information. Valuable tips and advice are offered in features such as From the Trenches, Coding Shots, Stop!, Caution!, Check This Out, and CMS Rules. Sample EHR screenshots (in Appendix D) show examples similar to the electronic health records students will encounter in the workplace.

Nanotheranostics

Nanotheranostics
  • Author : Mahendra Rai,Bushra Jamil
  • Publisher :Unknown
  • Release Date :2019-11-22
  • Total pages :409
  • ISBN : 9783030297688
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Summary : This book is specifically designed to provide information about various nanocarriers currently developed under the emerging field of nanotheranostics for a sustained, controlled, and targeted co-delivery of diagnostic and therapeutic agents. Diverse theranostic applications of nanotechnology and their limitations are also addressed. It integrates nanobiotechnology with theranostic applications. The combined term nanotheranostics has diverse application particularly in chemotherapy and other infectious diseases.Among other topics addressed are antimicrobial resistance, targeting intra-cellular pathogens, viruses and bacteria, chemotherapy, cancer therapeutics, and inflammatory disorders. This interdisciplinary volume is essential for a diverse group of readers including nanotechnologists, microbiologists, biotechnologists, bioengineering and bioprocess industry.

Mucosal Delivery of Drugs and Biologics in Nanoparticles

Mucosal Delivery of Drugs and Biologics in Nanoparticles
  • Author : Pavan Muttil,Nitesh K. Kunda
  • Publisher :Unknown
  • Release Date :2020-03-18
  • Total pages :277
  • ISBN : 9783030359102
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Summary : Nanotechnology has revolutionized the approach to designing and developing novel drug delivery systems. The last two decades have seen a great interest in the use of nanotechnology to offer efficient ways of delivering new and existing drugs and macromolecules. The focus of this book is the application of nanotechnology to deliver drugs and biological agents by the mucosal routes of administration i.e. nasal, pulmonary, buccal, and oral routes. It provides an overview of nanotechnology in drug delivery with a description of different types of nanoparticles, methods of preparation and characterization, and functionalization for site-specific drug delivery. The emphasis is on the use of nanoparticles in treating various cancers and infectious diseases. It broadens the use of nanoparticles by including biologics, including vaccines and immunotherapies, apart from drugs and acknowledges the concerns around the potential toxicity of nanoparticles to the host; several chapters will discuss the biodistribution of these nanoparticles when mucosal routes of administration are employed. Further, the interaction of nanoparticles with the host’s immune cells is discussed. Moreover, it reviews the regulatory aspects of nanotechnology in product development, especially when delivered by the mucosal route of administration. Lastly, discusses the challenges and opportunities to manufacture nanoparticles on an industrial scale. This book is the first of its kind to focus on the design, development and delivery of nanoparticles when administered by different mucosal routes.

Polymer Nanoparticles for Nanomedicines

Polymer Nanoparticles for Nanomedicines
  • Author : Christine Vauthier,Gilles Ponchel
  • Publisher :Unknown
  • Release Date :2017-01-07
  • Total pages :641
  • ISBN : 9783319414218
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Summary : This volume serves as a valuable handbook for the development of nanomedicines made of polymer nanoparticles because it provides researchers, students, and entrepreneurs with all the material necessary to begin their own projects in this field. Readers will find protocols to prepare polymer nanoparticles using different methods, since these are based on the variety of experiences that experts encounter in the field. In addition, complex topics such as, the optimal characterization of polymer nanoparticles is discussed, as well as practical guidelines on how to formulate polymer nanoparticles into nanomedicines, and how to modify the properties of nanoparticles to give them the different functionalities required to become an efficient nanomedicine for different clinical applications. The book also discusses the translation of technology from research to practice, considering aspects related to industrialization of preparation and aspects of regulatory and clinical development.

Pharmacology Test Prep

Pharmacology Test Prep
  • Author : Mario Babbini,Mary L. Thomas
  • Publisher :Unknown
  • Release Date :2014-12-15
  • Total pages :502
  • ISBN : 9781626230422
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Summary : Pharmacology Test Prep is an outstanding collection of 1500 clinical multiple-choice questions written according to USMLE guidelines and classified by learning objective and difficulty. The questions and answers in this book cover all the areas that are included in topic-based and organ system-based courses in the first two years of medical school. This book provides medical students preparing to take the USMLE with a thorough review of pharmacology concepts and is an excellent review book for those needing to brush up on pharmacology for their rotations. Key Features: Questions require students to analyze information before choosing the best answer Full explanations are included with answers, giving students a comprehensive USMLE review tool Organized along clinical as well as pharmacological lines, making it suitable for both Step 1 and Step 2 exam preparation

Surface Modification of Nanoparticles for Targeted Drug Delivery

Surface Modification of Nanoparticles for Targeted Drug Delivery
  • Author : Yashwant V Pathak
  • Publisher :Unknown
  • Release Date :2019-03-11
  • Total pages :499
  • ISBN : 9783030061159
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Summary : This unique book is the only one to discuss various new techniques developed to enhance the application of nanoparticulate drug delivery systems using surface modification of nanoparticles. The understanding of the surface characteristics nano-particles is growing significantly with the advent of new analytical techniques. Polymer chemistry is contributing to the development of many new versatile polymers which have abilities to accommodate many different, very reactive chemical groups, and can be used as a diagnostic tool, for better targeting, for more effective therapeutic results as well as for reducing the toxic and side effects of the drugs. Surface modification of such polymeric nanoparticles has been found by many scientists to enhance the application of nanoparticles and also allows the nano particles to carry specific drug molecule and disease /tumor specific antibodies which refine and improve drug delivery. Surface Modification of Nanoparticles for Targeted Drug Delivery is a collection essential information with various applications of surface modification of nanoparticles and their disease specific applications for therapeutic purposes.

Treatment of Cystic Fibrosis and Other Rare Lung Diseases

Treatment of Cystic Fibrosis and Other Rare Lung Diseases
  • Author : Arata Azuma,Michael S. Schechter
  • Publisher :Unknown
  • Release Date :2017-01-28
  • Total pages :263
  • ISBN : 9783034809771
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Summary : This volume describes the pathogenesis and pathophysiology of several pulmonary diseases as well as their treatment. It also discusses the underlying genetic and molecular biological basis, which opens the way for new treatments for these conditions. It focuses on the treatment of cystic fibrosis including CFTR (cystic fibrosis transmembrane-conductance regulator) modulator therapies, drug therapies that augment airway surface liquid as well as anti-inflammatory and anti-infective therapies. Further topics include long-term, low-dose macrolide therapy for diffuse panbronchiolitis; novel agents for previously untreatable idiopathic pulmonary fibrosis; possible new treatments for pulmonary alveolar proteinosis (PAP); and multiple novel therapeutic targets for treating lymphangiomyomatosis. Research into these conditions has led to major advances in our understanding of the underlying genetic and molecular basis of this disease, and to dramatic improvements in survival and quality of life for affected individuals.

External Field and Radiation Stimulated Breast Cancer Nanotheranostics

External Field and Radiation Stimulated Breast Cancer Nanotheranostics
  • Author : Nanasaheb D. Thorat,Joanna Bauer
  • Publisher :Unknown
  • Release Date :2019-09-26
  • Total pages :352
  • ISBN : 0750324171
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Summary : Nano drug-delivery systems responding to cellular local stimuli, such as pH, temperature and reductive agent's activation, i.e. enzymes, could effectively provide passive-mode desirable release but fail in disease treatment following the biological rhythms of brain tumor. This book is a compilation of research development lead by expert researchers and it establishes a single reference module. It addresses, for the first time, all translational aspects and clinical perspectives of physically stimulated breast-cancer nanotheranostics from a wide-ranging and multidisciplinary perception providing unrivalled and comprehensive knowledge in the field.

Nanostructures for Antimicrobial Therapy

Nanostructures for Antimicrobial Therapy
  • Author : Anton Ficai,Alexandru Mihai Grumezescu
  • Publisher :Unknown
  • Release Date :2017-05-29
  • Total pages :722
  • ISBN : 9780323461511
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Summary : Nanostructures for Antimicrobial Therapy discusses the pros and cons of the use of nanostructured materials in the prevention and eradication of infections, highlighting the efficient microbicidal effect of nanoparticles against antibiotic-resistant pathogens and biofilms. Conventional antibiotics are becoming ineffective towards microorganisms due to their widespread and often inappropriate use. As a result, the development of antibiotic resistance in microorganisms is increasingly being reported. New approaches are needed to confront the rising issues related to infectious diseases. The merging of biomaterials, such as chitosan, carrageenan, gelatin, poly (lactic-co-glycolic acid) with nanotechnology provides a promising platform for antimicrobial therapy as it provides a controlled way to target cells and induce the desired response without the adverse effects common to many traditional treatments. Nanoparticles represent one of the most promising therapeutic treatments to the problem caused by infectious micro-organisms resistant to traditional therapies. This volume discusses this promise in detail, and also discusses what challenges the greater use of nanoparticles might pose to medical professionals. The unique physiochemical properties of nanoparticles, combined with their growth inhibitory capacity against microbes has led to the upsurge in the research on nanoparticles as antimicrobials. The importance of bactericidal nanobiomaterials study will likely increase as development of resistant strains of bacteria against most potent antibiotics continues. Shows how nanoantibiotics can be used to more effectively treat disease Discusses the advantages and issues of a variety of different nanoantibiotics, enabling medics to select which best meets their needs Provides a cogent summary of recent developments in this field, allowing readers to quickly familiarize themselves with this topic area

Nanoengineering

Nanoengineering
  • Author : Patricia I. Dolez
  • Publisher :Unknown
  • Release Date :2015-05-26
  • Total pages :736
  • ISBN : 9780444627452
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Summary : Nanoengineering: Global Approaches to Health and Safety Issues provides a global vision on the impact of engineered nanomaterials both for the consumer/general public and in occupational settings. The book also presents a hint on what can be expected for the future from nanomaterials and their effects on our lives, both at home and at work. In addition, users will find valuable information on nanomaterials' irreplaceable value and their risks for health, safety, and environmental issues. Case studies illustrate key points and provide information on important processes. Provides a global vision on the different aspects related to nanosafety and a synthesis of the information available Gives all the information required for precision decision-making in a single book, offering both general public and occupational aspects Contains separate chapters on each subject written by world-renowned contributors Presents a complete vision of the problem, with perspectives on global approaches Includes case studies that illustrate important processes

Bioinformatics For Dummies

Bioinformatics For Dummies
  • Author : Jean-Michel Claverie,Cedric Notredame
  • Publisher :Unknown
  • Release Date :2011-02-10
  • Total pages :464
  • ISBN : 1118051106
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Summary : Were you always curious about biology but were afraid to sit through long hours of dense reading? Did you like the subject when you were in high school but had other plans after you graduated? Now you can explore the human genome and analyze DNA without ever leaving your desktop! Bioinformatics For Dummies is packed with valuable information that introduces you to this exciting new discipline. This easy-to-follow guide leads you step by step through every bioinformatics task that can be done over the Internet. Forget long equations, computer-geek gibberish, and installing bulky programs that slow down your computer. You’ll be amazed at all the things you can accomplish just by logging on and following these trusty directions. You get the tools you need to: Analyze all types of sequences Use all types of databases Work with DNA and protein sequences Conduct similarity searches Build a multiple sequence alignment Edit and publish alignments Visualize protein 3-D structures Construct phylogenetic trees This up-to-date second edition includes newly created and popular databases and Internet programs as well as multiple new genomes. It provides tips for using servers and places to seek resources to find out about what’s going on in the bioinformatics world. Bioinformatics For Dummies will show you how to get the most out of your PC and the right Web tools so you’ll be searching databases and analyzing sequences like a pro!

Colorectal Cancer

Colorectal Cancer
  • Author : Jim Khan
  • Publisher :Unknown
  • Release Date :2014-03-12
  • Total pages :532
  • ISBN : 9789535112310
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Summary : Colorectal cancer is one of the commonest cancers affecting individuals across the world. An improvement in survival has been attributed to multidisciplinary management, better diagnostics, improved surgical options for the primary and metastatic disease and advances in adjuvant therapy. In this book, international experts share their experience and knowledge on these different aspects in the management of colorectal cancer. An in depth analysis of screening for colorectal cancer, detailed evaluation of diagnostic modalities in staging colorectal cancer, recent advances in adjuvant therapy and principles and trends in the surgical management of colorectal cancer is provided. This will certainly prove to be an interesting and informative read for any clinician involved in the management of patients with colorectal cancer.

Nanomedicine and Cancer Therapies

Nanomedicine and Cancer Therapies
  • Author : Mathew Sebastian,Neethu Ninan,Eldho Elias
  • Publisher :Unknown
  • Release Date :2012-07-27
  • Total pages :250
  • ISBN : 9781926895185
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Summary : Nanotechnology has the power to radically change the way cancer is diagnosed, imaged, and treated. The holistic approach to cancer involves noninvasive procedures that emphasize restoring the health of human energy fields. Presenting a wealth of information and research about the most potent cancer healing therapies, this forward-thinking book explores how nanomedicine, holistic medicine, and other cancer therapies play important roles in treatment of this disease. Topics include nanobiotechnology for antibacterial therapy and diagnosis, mitochondrial dysfunction and cancer, antioxidants and combinatorial therapies, and optical and mechanical investigations of nanostructures for biomolecular detection.

Nanomedicine

Nanomedicine
  • Author : Yi Ge,Songjun Li,Shenqi Wang,Richard Moore
  • Publisher :Unknown
  • Release Date :2014-12-01
  • Total pages :413
  • ISBN : 9781461421405
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Summary : Increasing demand for and awareness of the applications of nanotechnology in medicine has resulted in the emergence of a new fast-growing multidisciplinary area - nanomedicine. This book offers comprehensive knowledge of and diverse perspectives on nanomedicine through two independent volumes. It aims to bridge the gap between nanotechnology and medicine through contributions by world-renowned experts from wide range of backgrounds including academia, industry, professional consultancy, and government agencies. Each contribution integrates knowledge from a wide range of areas to present the fundamentals of new applications and products of nanomedicine, as well as an outlook for the future. This book can well serve as a reference and guide for students, academics, researchers, scientists, engineers, clinicians, government researchers, and healthcare professionals.