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A Quick Guide to Metabolic Disease Testing Interpretation

A Quick Guide to Metabolic Disease Testing Interpretation
  • Author : Patricia Jones,Khushbu Patel,Dinesh Rakheja
  • Publisher :Unknown
  • Release Date :2020-07-31
  • Total pages :220
  • ISBN : 9780128169278
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Summary : Accurate interpretation of the organic acid chromatographs obtained from the gas chromatography/mass spectrometry requires a significant amount of practice. Pattern recognition is an important factor and a skill that is gained through time and effort. A Quick Guide to Metabolic Disease Testing Interpretation, Second Edition, provides these example chromatographs demonstrating specific disease-related metabolites for the inborn error of metabolism diagnosed via this method. One or more representative chromatographs from each of the common disorders is presented, with the important compounds noted on the chromatographs. This is a must-have for laboratory and medical professionals who interpret testing for the diagnosis and monitoring of IEM. Includes pathway diagrams and representative compound scans of important diagnostic compounds Provides illustrative chromatographs from selected disorders to aid in diagnosing common inborn errors of metabolism Highlights brief descriptions of the etiology and clinical presentation of each presented disorder

Quick Guide to Organic Acid Interpretation

Quick Guide to Organic Acid Interpretation
  • Author : Patricia M. Jones,Dinesh Rakheja
  • Publisher :Unknown
  • Release Date :2011
  • Total pages :147
  • ISBN : 1594251266
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Summary :

Inherited Metabolic Disease in Adults

Inherited Metabolic Disease in Adults
  • Author : Professor of Internal Medicine Division of Endocrinology and Metabolism Carla E M Hollak,Robin Lachmann,Consultant in Metabolic Medicine Head of Charles Dent Metabolic Unit Robin Lachmann
  • Publisher :Unknown
  • Release Date :2016-08-16
  • Total pages :648
  • ISBN : 9780199972135
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Summary : As clinical management of inherited metabolic diseases (IMDs) has improved, more patients affected by these conditions are surviving into adulthood. This trend, coupled with the widespread recognition that IMDs can present differently and for the first time during adulthood, makes the need for a working knowledge of these diseases more important than ever. Inherited Metabolic Disease in Adults offers an authoritative clinical guide to the adult manifestations of these challenging and myriad conditions. These include both the classic pediatric-onset conditions and a number of new diseases that can manifest at any age. It is the first book to give a clear and concise overview of how this group of conditions affects adult patients, a that topic will become a growing imperative for physicians across primary and specialized care.

Inherited Metabolic Diseases

Inherited Metabolic Diseases
  • Author : Georg F. Hoffmann,Johannes Zschocke,William L. Nyhan
  • Publisher :Unknown
  • Release Date :2009-11-21
  • Total pages :386
  • ISBN : 3540747230
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Summary : The explosion of insights in the field of metabolic disease has shed new light on diagnostic as well as treatment options. ‘Inherited Metabolic Disease – A Clinical Approach’ is written with a reader-friendly consistent structure. It helps the reader to find the information in an easily accessible and rapid way when needed. Starting with an overview of the major groups of metabolic disorders it includes algorithms with questions and answers as well as numerous graphs, metabolic pathways, and an expanded index. Clinical and diagnostic details with a system and symptom based are given to facilitate an efficient and yet complete diagnostic work-up of individual patients. Further, it offers helpful advice for emergency situations, such as hypoglycemia, hyperammonemia, lactic acidosis or acute encephalopathy. Five different indices allow a quick but complete orientation for common important constellations. Last but not least, it has an appendix with a guide to rapid differential diagnosis of signs and symptoms and when not to suspect metabolic disease. It will help physicians to diagnose patients they may otherwise fail to diagnose and to reduce unnecessary referrals. For metabolic and genetic specialists especially the indices will be helpful as a quick look when being called for advice. It has all it needs to become a gold standard defining the clinical practice in this field.

Small Animal Clinical Diagnosis by Laboratory Methods - E-Book

Small Animal Clinical Diagnosis by Laboratory Methods - E-Book
  • Author : Michael D. Willard,Harold Tvedten
  • Publisher :Unknown
  • Release Date :2011-12-23
  • Total pages :432
  • ISBN : 9781437706581
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Summary : A quick guide to appropriately selecting and interpreting laboratory tests, Small Animal Clinical Diagnosis by Laboratory Methods, 5th Edition helps you utilize your in-house lab or your specialty reference lab to efficiently make accurate diagnoses without running a plethora of unnecessary and low-yield tests. It provides answers to commonly asked questions relating to laboratory tests, and solutions to frequently encountered problems in small animal diagnosis. For easy reference, information is provided by clinical presentation and abnormalities, and includes hundreds of tables, boxes, key points, and algorithms. This edition, now in full color, is updated with the latest advances in laboratory testing methods and diagnostic problem solving. Written by noted educators Dr. Michael Willard and Dr. Harold Tvedten, this book may be used as an on-the-spot guide to specific problems or conditions as well as a reference for more detailed research on difficult cases. Concise discussions address laboratory approaches to various disorders, possible conclusions from various test results, artifacts and errors in diagnoses, and interpretations leading to various diagnoses. Hundreds of tables, boxes, algorithms, and key points offer at-a-glance information including cautions, common pitfalls, and helpful "pearls," and lead to proper differential and clinical diagnostic decision making. Note boxes identify key considerations in correlating clinical signs with test data for accurate diagnoses, highlight safety precautions, and offer helpful tips for sample preparation and interpretation. Chapters on laboratory diagnostic toxicology and therapeutic drug monitoring help in handling potentially fatal poisonings and other special situations. Expert editors and contributors provide clinical knowledge and successful diagnostic problem-solving solutions. A practical appendix lists referral laboratories that may be contacted for certain diseases, and reference values with the normal or expected range for coagulation, hematology, and more. Updated coverage integrates the newest advances in testing methods and diagnostic problem solving. Full-color photos and schematic drawings are placed adjacent to related text, and accurately depict diagnostic features on microscopic slide preparations as well as test procedures and techniques.

Pediatric Endocrinology and Inborn Errors of Metabolism

Pediatric Endocrinology and Inborn Errors of Metabolism
  • Author : Kyriakie Sarafoglou,Georg F. Hoffmann,Karl S. Roth
  • Publisher :Unknown
  • Release Date :2012-09-01
  • Total pages :964
  • ISBN : 9780071811576
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Summary : Fast, crystal-clear guidance on managing both pediatric endocrine disorders and inborn errors of metabolism A Doody's Core Title for 2011! New England Journal of Medicine Review! "...an inspiring learning tool....Sarafoglou and colleagues have combined their expertise to create an informative and timely textbook in which the explanations of underlying mechanisms guide the structure of each chapter. It is a unique book that is pleasing to the eye, nurturing for the mind, and instructive for a broad readership."--New England Journal of Medicine 4 STAR DOODY'S REVIEW! "The book covers various pathophysiologic aspects of each endocrine organ and its interaction with other endocrine and nonendocrine systems. Disorders of thyroid and adrenal glands, pituitary, reproductive organs, and endocrine neoplasia are extensively covered. Most large groups of metabolic diseases are reviewed as well. Concise, pertinent information is provided on mitochondrial and fatty-acid oxidation, urea cycle and glycogen storage disorders, as well as organic acidurias and amino acidopathies. The most useful and user-friendly areas are the 1-to-2-page "at-a-glance" sections in each chapter which provide concise yet pertinent information about the disorders within a particular group of endocrine disturbances or IEM. This is a well written book and the multiple visual aids greatly assist in comprehension and memorization of the material...I strongly recommend this book without reservation." -- Doody's In one practical, user-friendly tutorial, a team of international contributors delivers the latest information and clinical insights you need to confidently diagnose and manage pediatric patients. This full-color resource guides you through the etiology, pathophysiology, presenting signs and symptoms, diagnostic laboratory examinations, and treatments regimens of each disorder. Features: Full-color presentation with numerous photos, illustrations, diagnostic algorithms, tables, and text boxes that summarize key concepts and assist in the decision-making process At-a-Glance feature beginning each disease-based chapter summarizes all the clinical information you need to differentiate between disorder sub-types in one easy-to-find place All-inclusive coverage encompasses the full spectrum of critical topics Emergency assessment and treatment chapter gives you fast, clear guidance on acute presentations of endocrine and metabolic disorders Chapter on newborn screening walks you through an abnormal screening result to follow-up diagnostic testing Complete and detailed information on all laboratory and radiographic testing used to diagnose disorders in both disciplines

Quick Guide to Clinical Chemistry

Quick Guide to Clinical Chemistry
  • Author : Janelle M. Chiasera,Robert W. Hardy,John A. Smith
  • Publisher :Unknown
  • Release Date :2012
  • Total pages :229
  • ISBN : 1594251444
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Summary :

Assessing Genetic Risks

Assessing Genetic Risks
  • Author : Institute of Medicine,Committee on Assessing Genetic Risks
  • Publisher :Unknown
  • Release Date :1994-01-01
  • Total pages :352
  • ISBN : 9780309047982
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Summary : Raising hopes for disease treatment and prevention, but also the specter of discrimination and "designer genes," genetic testing is potentially one of the most socially explosive developments of our time. This book presents a current assessment of this rapidly evolving field, offering principles for actions and research and recommendations on key issues in genetic testing and screening. Advantages of early genetic knowledge are balanced with issues associated with such knowledge: availability of treatment, privacy and discrimination, personal decisionmaking, public health objectives, cost, and more. Among the important issues covered: Quality control in genetic testing. Appropriate roles for public agencies, private health practitioners, and laboratories. Value-neutral education and counseling for persons considering testing. Use of test results in insurance, employment, and other settings.

Drug Metabolism and Pharmacokinetics Quick Guide

Drug Metabolism and Pharmacokinetics Quick Guide
  • Author : Siamak Cyrus Khojasteh,Harvey Wong,Cornelis E.C.A. Hop
  • Publisher :Unknown
  • Release Date :2011-04-07
  • Total pages :214
  • ISBN : 1441956298
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Summary : Drug Metabolism and Pharmacokinetics Quick Guide covers a number of aspects of drug assessment at drug discovery and development stages, topics such as pharmacokinetics, absorption, metabolism, enzyme kinetics, drug transporters, drug interactions, drug-like properties, assays and in silico calculations. It covers key concepts, with useful tables on physiological parameters (eg. blood flow to organs in x-species, expression and localization of enzymes and transporters), chemical structure, nomenclature, and moieties leading to bioactivation (with examples). Overall it includes a number of key topics useful at the drug discovery stage, which would serve as a quick reference with several examples from the literature to illustrate the concept.

Biomarkers in Inborn Errors of Metabolism

Biomarkers in Inborn Errors of Metabolism
  • Author : Uttam Garg,Laurie D. Smith
  • Publisher :Unknown
  • Release Date :2017-06-07
  • Total pages :476
  • ISBN : 9780128029183
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Summary : Biomarkers of Inborn Errors in Metabolism: Clinical Aspects and Laboratory Determination is structured around the new reality that laboratory testing and biomarkers are an integral part in the diagnosis and treatment of inherited metabolic diseases. The book covers currently used biomarkers as well as markers that are in development. Because biomarkers used in the initial diagnosis of disease may be different than the follow-up markers, the book also covers biomarkers used in both the prognosis and treatment of inherited metabolic disorders. With the introduction of expanded new-born screening for inborn metabolic diseases, an increasing numbers of laboratories are involved in follow-up confirmatory testing. The book provides guidance on laboratory test selection and interpreting results in patients with suspected inherited metabolic diseases. The book provides comprehensive guidance on patient diagnosis and follow-up through its illustrative material on metabolic pathways, genetics and pathogenesis, treatment and prognosis of inherited metabolic diseases, along with essential information on clinical presentation. Each chapter is organized with a uniform, easy-to-follow format: a brief description of the disorder and pathway; a description of treatment; biomarkers for diagnosis; biomarkers followed for treatment efficacy; biomarkers followed for disease progression; confounding conditions that can either: affect biomarker expression or mimic IEMs; other biomarkers: less established, future. Provides comprehensive information on the tests/biomarkers selection in newborn screening and follow-up of newborn screens Categorizes biomarkers into diagnostic markers, disease follow-up markers, and prognostic biomarkers Covers confounding factors that can alter biomarkers in the absence of inborn errors of metabolism Offers guidance on how to distinguish acquired causes from inborn errors of metabolism

Inherited Metabolic Epilepsies

Inherited Metabolic Epilepsies
  • Author : Phillip L. Pearl, MD
  • Publisher :Unknown
  • Release Date :2012-10-04
  • Total pages :312
  • ISBN : 9781617050565
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Summary : The explosion of information in neurogenetics and metabolism mandates increasing awareness of appropriate diagnostic and therapeutic strategies in the setting of certain epilepsies, especially those of very early onset. There are over 200 inherited disorders that are associated with seizures and prompt identification and intervention is crucial for a positive outcome. This text brings together leading authorities presenting state-of-the-art clinical reviews covering the science, recognition, and treatment of the inherited metabolic epilepsies and related disorders. Inherited Metabolic Epilepsies opens with a section on general principles for diagnosis and targeted intervention including screening protocols, laboratory testing, neuroimaging, seizure patterns and EEG findings, new technologies, and the ketogenic diet in metabolic epilepsies. The next two sections are devoted to the cohort of specific small molecule disorders (aminoacidopathies, organic acidopathies, mitochondrial disorders, urea cycle disorders, neurotransmitter disorders, and glucose-related disorders) and large molecule disorders (lysomal storage disorders, peroxisomal diseases, glycosylation defects, and leukodystrophies) that are treatable yet can be so vexing to clinicians and investigators. The book concludes with a clinical algorithm designed to be a resource for the physician in search of direction when considering an inherited metabolic disorder as the explanation for a patient with epilepsy. Inherited Metabolic Epilepsies Key Features: Presents the latest scientific thinking and clinical wisdom for a poorly understood group of disorders that have devastating consequences if unrecognized or not promptly treated Expert authorship from both the genetic-metabolic and epilepsy communities provides state-of-the-art guidance for understanding and managing these disorders A readable text for clinicians highlighting the relation between metabolic errors and epilepsy Concludes with a practical algorithm for evaluating a patient with a possible metabolic epilepsy

Statistical Power Analysis for the Behavioral Sciences

Statistical Power Analysis for the Behavioral Sciences
  • Author : Jacob Cohen
  • Publisher :Unknown
  • Release Date :2013-05-13
  • Total pages :567
  • ISBN : 9781134742776
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Summary : Statistical Power Analysis is a nontechnical guide to power analysis in research planning that provides users of applied statistics with the tools they need for more effective analysis. The Second Edition includes: * a chapter covering power analysis in set correlation and multivariate methods; * a chapter considering effect size, psychometric reliability, and the efficacy of "qualifying" dependent variables and; * expanded power and sample size tables for multiple regression/correlation.

Laboratory Guide to the Methods in Biochemical Genetics

Laboratory Guide to the Methods in Biochemical Genetics
  • Author : Nenad Blau,Marinus Duran,K. Michael Gibson
  • Publisher :Unknown
  • Release Date :2008-05-31
  • Total pages :860
  • ISBN : 9783540766988
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Summary : This manual deals specifically with laboratory approaches to diagnosing inborn errors of metabolism. The key feature is that each chapter is sufficiently detailed so that any individual can adopt the described method into their own respective laboratory.

Understanding Genetics

Understanding Genetics
  • Author : Genetic Alliance,New York-Mid-Atlantic Consortium for Genetic and Newborn Screening Services
  • Publisher :Unknown
  • Release Date :2009
  • Total pages :100
  • ISBN : 9780982162217
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Summary : The purpose of this manual is to provide an educational genetics resource for individuals, families, and health professionals in the New York - Mid-Atlantic region and increase awareness of specialty care in genetics. The manual begins with a basic introduction to genetics concepts, followed by a description of the different types and applications of genetic tests. It also provides information about diagnosis of genetic disease, family history, newborn screening, and genetic counseling. Resources are included to assist in patient care, patient and professional education, and identification of specialty genetics services within the New York - Mid-Atlantic region. At the end of each section, a list of references is provided for additional information. Appendices can be copied for reference and offered to patients. These take-home resources are critical to helping both providers and patients understand some of the basic concepts and applications of genetics and genomics.

Basic Skills in Interpreting Laboratory Data

Basic Skills in Interpreting Laboratory Data
  • Author : Mary Lee
  • Publisher :Unknown
  • Release Date :2013-06-01
  • Total pages :664
  • ISBN : 9781585283453
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Summary : Basic Skills in Interpreting Laboratory Data, Fifth Edition, is the classic and most popular pharmacy laboratory text because it is the only reference on this subject written by pharmacists, for pharmacists. Students find this guide a clear and useful introduction to the fundamentals of interpreting laboratory test results. The book enhances the skills pharmacists need by providing essential information on common laboratory tests used to screen for or diagnose diseases and monitor the effectiveness and safety of treatment and disease severity. Each chapter contains learning objectives, case studies, bibliographies, and charts that summarize the causes of high and low test results. New for this edition: Updated and expanded Quick View tables in each chapter now match those in the popular quick-reference, Interpreting Laboratory Data: A Point-of-Care Guide New glossary of acronyms is right up front for a streamlined reference Normal value ranges of all tests have been standardized by an expert pathologist New and updated cases in each chapter apply your Basic Skills in clinical situations Reorganized to highlight the application of concepts by body system, and in special populations Basic Skills in Interpreting Laboratory Data offers features that will help pharmacy students not only understand and engage with the material but also will streamline the transition from classroom to practice setting. After studying with this trusted text, students and pharmacists will more effectively monitor patient therapy, evaluate test results, and improve outcomes through optimal and focused pharmacotherapy.

Improving Diagnosis in Health Care

Improving Diagnosis in Health Care
  • Author : National Academies of Sciences, Engineering, and Medicine,Institute of Medicine,Board on Health Care Services,Committee on Diagnostic Error in Health Care
  • Publisher :Unknown
  • Release Date :2016-01-29
  • Total pages :472
  • ISBN : 9780309377690
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Summary : Getting the right diagnosis is a key aspect of health care - it provides an explanation of a patient's health problem and informs subsequent health care decisions. The diagnostic process is a complex, collaborative activity that involves clinical reasoning and information gathering to determine a patient's health problem. According to Improving Diagnosis in Health Care, diagnostic errors-inaccurate or delayed diagnoses-persist throughout all settings of care and continue to harm an unacceptable number of patients. It is likely that most people will experience at least one diagnostic error in their lifetime, sometimes with devastating consequences. Diagnostic errors may cause harm to patients by preventing or delaying appropriate treatment, providing unnecessary or harmful treatment, or resulting in psychological or financial repercussions. The committee concluded that improving the diagnostic process is not only possible, but also represents a moral, professional, and public health imperative. Improving Diagnosis in Health Care a continuation of the landmark Institute of Medicine reports To Err Is Human (2000) and Crossing the Quality Chasm (2001) finds that diagnosis-and, in particular, the occurrence of diagnostic errorsâ€"has been largely unappreciated in efforts to improve the quality and safety of health care. Without a dedicated focus on improving diagnosis, diagnostic errors will likely worsen as the delivery of health care and the diagnostic process continue to increase in complexity. Just as the diagnostic process is a collaborative activity, improving diagnosis will require collaboration and a widespread commitment to change among health care professionals, health care organizations, patients and their families, researchers, and policy makers. The recommendations of Improving Diagnosis in Health Care contribute to the growing momentum for change in this crucial area of health care quality and safety.

Inherited Metabolic Diseases

Inherited Metabolic Diseases
  • Author : Georg F. Hoffmann,Johannes Zschocke,William L. Nyhan
  • Publisher :Unknown
  • Release Date :2016-09-20
  • Total pages :605
  • ISBN : 9783662494103
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Summary : This book focuses on clinical presentations that may be caused by inherited metabolic diseases. Its symptom- and system-based approach will help clinicians with and without detailed knowledge of human biochemistry in all specialties to reach a correct diagnosis and institute the optimal treatment program. The book summarizes the central elements of inherited metabolic diseases and describes clearly how to carry out an efficient yet complete diagnostic work-up, thereby guiding the clinician from the presenting symptoms and signs through to effective initial management. After an introduction to the different disorders, the book explains when to consider an inborn metabolic error and which initial tests to order. Core aspects such as structured communication, guidelines, transition, pregnancy, maternal care and how to respond to various medical emergencies are covered. Therapeutic concepts such as dietary treatment are delineated and practical advice provided on the quite different treatment approaches required for individual diseases. An extensive section structured according to organ systems outlines the correct approach in the context of specific symptoms and signs. The value of each of the potential investigations is explained, with precise advice on the interpretation of results. The inclusion of algorithms, tables, lists, and charts facilitates rapid decision making and information retrieval, and the appendices include a helpful guide to differential diagnosis based on clinical and biochemical phenotypes. This new updated edition of Inherited Metabolic Diseases will be an invaluable aid for the busy clinician and an excellent quick reference for metabolic and genetic specialists.

Ferri's Best Test

Ferri's Best Test
  • Author : Fred F. Ferri
  • Publisher :Unknown
  • Release Date :2009-04-14
  • Total pages :448
  • ISBN : 9780323078610
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Summary : Written by Fred F. Ferri, MD, FACP, author of many best-selling books for primary care practice, Ferri’s Best Test, 2nd Edition, equips you to quickly choose the most efficient and cost-effective diagnostic approach, including imaging or lab tests. Updates throughout, including more than 180 new tests...additional diagnostic modalities...and new algorithms...make this unique and user-friendly reference a must for determining which diagnostic tests to order. A portable, pocket-sized format allows for convenient consultation anytime, anywhere. Offers concise, well-organized guidance to the most common lab tests and diagnostic imaging modalities, all in one single resource, that makes reference remarkably fast and easy. Describes the most common imaging studies for each organ system, reviewing their indications, advantages, disadvantages, and approximate costs to simplify your decision-making process. Examines over 384 laboratory tests, describing the normal range of results in adult patients, typical abnormalities (positive tests, increased or decreased values), and the likeliest causes. Explores 231 common diseases and disorders, providing algorithms to help you select the single best test for diagnosing each condition. Features a portable, pocket-sized format that allows for convenient consultation anytime, anywhere. Features 184 new tests in an expanded laboratory test section; 8 additional diagnostic radiological modalities, including computed tomographic colonography, video capsule endoscopy, and intravascular ultrasonography; and 30 new algorithms in an expanded algorithm section, to provide you with the latest options for obtaining optimal diagnostic outcomes. Includes IU units added to all laboratory tests, to make the guidance more useful to clinicians practicing outside of the US.

Handbook of Clinical Biochemistry

Handbook of Clinical Biochemistry
  • Author : R. Swaminathan
  • Publisher :Unknown
  • Release Date :2011
  • Total pages :816
  • ISBN : 9789812837394
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Summary : This book discusses the clinical biochemistry of commonly measured analytes. It gives hard numerical data not only for the distribution and balance of analytes, but also for differential diagnosis and treatment. For each analyte distribution, balance and assessment of status, causes and consequences of abnormal values, investigation and treatment options are presented. Every chapter begins with a brief review of the physiology and biochemistry, followed by descriptions of the changes in diseases and how biochemical tests may help in their diagnosis and management. The principle behind the normal and abnormal functions of tissues and organs is explained. This book provides clear and concise coverage for medical students, junior doctors, clinical biochemists and medical technologists.

Quick guide to Laboratory Medicine: a student's overview

Quick guide to Laboratory Medicine: a student's overview
  • Author : Armando Guerra-Ruiz,Bernardo Lavin,Mayte Garcia Unzueta
  • Publisher :Unknown
  • Release Date :2017-09-15
  • Total pages :70
  • ISBN : 9783962551742
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Summary : This book provides an overview of useful laboratory tests as complementary tests for the diagnosis of common ailments and diseases in standard medical practice. The reader will find a concise but detailed guide to the tests, their rationale and their interpretation.

The American Psychiatric Association Practice Guidelines for the Psychiatric Evaluation of Adults, Third Edition

The American Psychiatric Association Practice Guidelines for the Psychiatric Evaluation of Adults, Third Edition
  • Author : American Psychiatric Association
  • Publisher :Unknown
  • Release Date :2015-07-29
  • Total pages :170
  • ISBN : 9780890424650
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Summary : Since the publication of the Institute of Medicine (IOM) report Clinical Practice Guidelines We Can Trust in 2011, there has been an increasing emphasis on assuring that clinical practice guidelines are trustworthy, developed in a transparent fashion, and based on a systematic review of the available research evidence. To align with the IOM recommendations and to meet the new requirements for inclusion of a guideline in the National Guidelines Clearinghouse of the Agency for Healthcare Research and Quality (AHRQ), American Psychiatric Association (APA) has adopted a new process for practice guideline development. Under this new process APA's practice guidelines also seek to provide better clinical utility and usability. Rather than a broad overview of treatment for a disorder, new practice guidelines focus on a set of discrete clinical questions of relevance to an overarching subject area. A systematic review of evidence is conducted to address these clinical questions and involves a detailed assessment of individual studies. The quality of the overall body of evidence is also rated and is summarized in the practice guideline. With the new process, recommendations are determined by weighing potential benefits and harms of an intervention in a specific clinical context. Clear, concise, and actionable recommendation statements help clinicians to incorporate recommendations into clinical practice, with the goal of improving quality of care. The new practice guideline format is also designed to be more user friendly by dividing information into modules on specific clinical questions. Each module has a consistent organization, which will assist users in finding clinically useful and relevant information quickly and easily. This new edition of the practice guidelines on psychiatric evaluation for adults is the first set of the APA's guidelines developed under the new guideline development process. These guidelines address the following nine topics, in the context of an initial psychiatric evaluation: review of psychiatric symptoms, trauma history, and treatment history; substance use assessment; assessment of suicide risk; assessment for risk of aggressive behaviors; assessment of cultural factors; assessment of medical health; quantitative assessment; involvement of the patient in treatment decision making; and documentation of the psychiatric evaluation. Each guideline recommends or suggests topics to include during an initial psychiatric evaluation. Findings from an expert opinion survey have also been taken into consideration in making recommendations or suggestions. In addition to reviewing the available evidence on psychiatry evaluation, each guideline also provides guidance to clinicians on implementing these recommendations to enhance patient care.