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Alcohol, Drugs, Genes and the Clinical Laboratory

Alcohol, Drugs, Genes and the Clinical Laboratory
  • Author : Amitava Dasgupta
  • Publisher :Unknown
  • Release Date :2016-10-17
  • Total pages :236
  • ISBN : 9780128093344
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Summary : Alcohol, Drugs, Genes and the Clinical Laboratory provides an overview and quick reference to genetic relationships and clinical laboratory information related to the serious public health issue of alcohol and drug abuse. Written in a clear and concise manner, this book discusses the necessary information for health and safety professionals working in public health to learn about complex issues quickly to better help their patients, employees, and others affected by alcohol and drug abuse. Alcohol, Drugs, Genes and the Clinical Laboratory covers the important aspects of drugs and alcohol abuse including genetic aspects along with laboratory methods for analysis of alcohol and abused drugs with emphasis on false positive test results. The book is helpful to healthcare professionals, such as pathologists who oversee alcohol and drug testing, emergency room physicians, family practice physicians who are first healthcare professionals who identify patients susceptible to drug and alcohol abuse, and psychiatrists involved with drug and alcohol rehabilitation programs. It will also be useful to safety professionals who have to assess individuals for workplace responsibilities, ranging from police and recruitment to occupational safety and occupational medicine and public health officials. Features accessible language for healthcare and safety professionals who are not experts in laboratory procedures Provides examples from clinical and everyday situations Explains how to interpret laboratory results and the latest genetic factors regarding drug and alcohol abuse

Pharmacogenomics of Alcohol and Drugs of Abuse

Pharmacogenomics of Alcohol and Drugs of Abuse
  • Author : Amitava Dasgupta,Loralie J. Langman
  • Publisher :Unknown
  • Release Date :2012-04-23
  • Total pages :252
  • ISBN : 9781439856123
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Summary : Pharmacogenomics is the basis of personalized medicine, which is said to be the medicine of the future. Understanding genetic variation in drug and alcohol response is vital for professionals working in rehabilitation programs. The same principles that are applicable for therapeutic drugs are also applicable for drugs of abuse. Pharmacogenomics can supplement traditional therapeutic drug monitoring, potentially predicting correct dosage before initiation of the drug therapy. Applying these principles to testing and treatment, Pharmacogenomics of Alcohol and Drugs of Abuse discusses the role of the clinical laboratory in the practice of personalized medicine. With contributions from a range of experts, the book presents the genetic aspects of alcohol metabolism and other drugs including marijuana, cocaine, and amphetamines. In addition to basic pharmacogenomic aspects, the book addresses slate and trait markers of drugs of abuse so readers can consider setting appropriate biomarker tests in their clinical laboratory.

Alcohol and Its Biomarkers

Alcohol and Its Biomarkers
  • Author : Amitava Dasgupta
  • Publisher :Unknown
  • Release Date :2015-02-18
  • Total pages :312
  • ISBN : 9780128004098
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Summary : Alcohol and Its Biomarkers: Clinical Aspects and Laboratory Determination is a concise guide to all currently known alcohol biomarkers, their clinical application, and the laboratory methods used to detect them. Pathologists can use this resource to understand the limitations and cost factors associated with each method for determining certain alcohol biomarkers. In addition, interferences in these determinations are discussed, so that clinicians can understand the causes of falsely elevated biomarkers and pathologists and laboratory scientists can potentially eliminate them. The book focuses on the analytical methods used to detect alcohol in blood and urine, the limitations of alcohol determination using enzymatic methods, and the differences between clinical and forensic alcohol measurement. Chapters also cover cutting-edge alcohol biomarkers for potential use. Focuses on the analytical methods used for detecting alcohol in blood and urine along with the pitfalls and limitations of alcohol determination using enzymatic methods Explains the difference between clinical and forensic alcohol measurement Includes a brief overview of the benefits of consuming alcohol in moderation and the hazards of heavy drinking

Accurate Results in the Clinical Laboratory

Accurate Results in the Clinical Laboratory
  • Author : Amitava Dasgupta,Jorge L. Sepulveda
  • Publisher :Unknown
  • Release Date :2013-01-22
  • Total pages :382
  • ISBN : 9780124158580
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Summary : This practical, easy-to-use guide, named to Doody’s Core Titles 2013, addresses interference issues in all laboratory tests, including patient epigenetics, process of specimen collection, enzymes, biomarkers. Clinicians and laboratory scientists can therefore rely on one reference which speaks to both their needs of accurate specimen analysis and optimal patient care. Erroneous hospital and pathology laboratory results can be confusing and problematic, especially in acute care situations. While some factors creating interference, can be identified in the laboratory, detecting many others is often dependent on clinical details unavailable to the laboratory scientists or pathologists. Therefore, clinicians must become proficient in identifying such erroneous reports, and working with pathologists and laboratory scientists so that they can understand the source of such interferences, correct the results, and then decide what course of action must be followed for proper patient management. Named to Doody’s Core Titles 2013, a collection development tool for health sciences libraries of all sizes, by Doody Enterprises Practical information for both clinicians and laboratory scientists, presented in the form of tables and charts for easy reference Focus on range and sources of interferences rather than details of toxicologic mechanisms which are well covered in toxicology textbooks Covers interferences across endocrine, oncology, hematology, immunohistochemistry, immunology, serology, microbiology, and molecular testing

Critical Issues in Alcohol and Drugs of Abuse Testing

Critical Issues in Alcohol and Drugs of Abuse Testing
  • Author : Amitava Dasgupta
  • Publisher :Unknown
  • Release Date :2019-01-10
  • Total pages :560
  • ISBN : 9780128156087
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Summary : Critical Issues in Alcohol and Drugs of Abuse Testing, Second Edition, addresses the general principles and technological advances for measuring drugs and alcohol, along with the pitfalls of drugs of abuse testing. Many designer drugs, for example, are not routinely tested in drugs of abuse panels and may go undetected in a drug test. This updated edition is a must-have for clinical pathologists, toxicologists, clinicians, and medical review officers and regulators, bridging the gap between technical and clinical information. Topics of note include the monitoring of pain management drugs, bath salts, spices (synthetic marijuana), designer drugs and date rape drugs, and more. Serves as a ready resource of information for alcohol and drug testing Ideal resource for making decisions related to the monitoring and interpretation of results Includes concise content for clinical laboratory scientists, toxicologists and clinicians

Human Drug Metabolism

Human Drug Metabolism
  • Author : Michael D. Coleman
  • Publisher :Unknown
  • Release Date :2020-02-19
  • Total pages :680
  • ISBN : 9781119458562
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Summary : Provides a timely update to a key textbook on human drug metabolism The third edition of this comprehensive book covers basic concepts of teaching drug metabolism, starting from extreme clinical consequences to systems and mechanisms and toxicity. It provides an invaluable introduction to the core areas of pharmacology and examines recent progress and advances in this fast moving field and its clinical impact. Human Drug Metabolism, 3rd Edition begins by covering basic concepts such as clearance and bioavailability, and looks at the evolution of biotransformation, and how drugs fit into this carefully managed biological environment. More information on how cytochrome P450s function and how they are modulated at the sub-cellular level is offered in this new edition. The book also introduces helpful concepts for those struggling with the relationship of pharmacology to physiology, as well as the inhibition of biotransformational activity. Recent advances in knowledge of a number of other metabolizing systems are covered, including glucuronidation and sulphation, along with the main drug transporters. Also, themes from the last edition are developed in an attempt to chart the progress of personalized medicine from concepts towards practical inclusion in routine therapeutics. The last chapter focuses on our understanding of how and why drugs injure us, both in predictable and unpredictable ways. Appendix A highlights some practical approaches employed in both drug metabolism research and drug discovery, whilst Appendix B outlines the metabolism of some drugs of abuse. Appendix C advises on formal examination preparation and Appendix D lists some substrates, inducers and inhibitors of the major human cytochrome P450s. Fully updated to reflect advances in the scientific field of drug metabolism and its clinical impact Reflects refinements in the author's teaching method, particularly with respect to helping students understand biological systems and how they operate Illustrates the growing relationship between drug metabolism and personalized medicine Includes recent developments in drug discovery, genomics, and stem cell technologies Human Drug Metabolism, 3rd Edition is an excellent book for advanced undergraduate and graduate students in molecular biology, biochemistry, pharmacology, pharmacy, and toxicology. It will also appeal to professionals interested in an introduction to this field, or who want to learn more about these bench-to-bedside topics to apply it to their practice.

Clinical Chemistry, Immunology and Laboratory Quality Control

Clinical Chemistry, Immunology and Laboratory Quality Control
  • Author : Amitava Dasgupta,Amer Wahed
  • Publisher :Unknown
  • Release Date :2013-12-02
  • Total pages :504
  • ISBN : 9780124079359
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Summary : All pathology residents must have a good command of clinical chemistry, toxicology, immunology, and laboratory statistics to be successful pathologists, as well as to pass the American Board of Pathology examination. Clinical chemistry, however, is a topic in which many senior medical students and pathology residents face challenges. Clinical Chemistry, Immunology and Laboratory Quality Control meets this challenge head on with a clear and easy-to-read presentation of core topics and detailed case studies that illustrate the application of clinical chemistry knowledge to everyday patient care. This basic primer offers practical examples of how things function in the pathology clinic as well as useful lists, sample questions, and a bullet-point format ideal for quick pre-Board review. While larger textbooks in clinical chemistry provide highly detailed information regarding instrumentation and statistics, this may be too much information for students, residents, and clinicians. This book is designed to educate senior medical students, residents, and fellows, and to "refresh" the knowledge base of practicing clinicians on how tests are performed in their laboratories (i.e., method principles, interferences, and limitations). Takes a practical and easy-to-read approach to understanding clinical chemistry and toxicology Covers all important clinical information found in larger textbooks in a more succinct and easy-to-understand manner Covers essential concepts in instrumentation and statistics in such a way that fellows and clinicians understand the methods without having to become specialists in the field Includes chapters on drug-herb interaction and pharmacogenomics, topics not covered by textbooks in the field of clinical chemistry or laboratory medicine

Fighting the Opioid Epidemic

Fighting the Opioid Epidemic
  • Author : Amitava Dasgupta
  • Publisher :Unknown
  • Release Date :2020-07-22
  • Total pages :160
  • ISBN : 9780128223901
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Summary : Fighting the Opioid Epidemic: The Role of Providers and the Clinical Laboratory in Understanding Who Is Vulnerable covers the important aspects that are essential in fighting the opioid epidemic. This succinct reference highlights how the toxicology laboratory can play a vital role in fighting the opioid epidemic by implementing a robust system for drugs of abuse testing as well as drug testing in pain management patients. It targets health care professionals in a technical manner, discussing polymorphisms of important genes that may be associated with increased vulnerability of alcohol and drug addiction to an individual. Covers all important aspects of opioid abuse, including genetic and environmental factors Discusses pharmacology, toxicology and the pharmacogenomics related to opioid metabolism Presents genetic and environmental factors associated with those vulnerable to opioid addiction, as well as the pitfalls of drug testing in pain management

The Genetics of Alcoholism

The Genetics of Alcoholism
  • Author : Henri Begleiter,Benjamin Kissin
  • Publisher :Unknown
  • Release Date :1995
  • Total pages :400
  • ISBN : 0195088778
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Summary : The Genetics of Alcoholism introduces a new series, `Alcohol and Alcoholism', that will cover most of the significant aspects - biological, psychological and social - of this subject. The series' theoretical framework will be the biopsychosocial approach. This first volume addresses in depth the genetic influences that contribute ultimately to the development of alcoholism. It is the first comprehensive book on this subject.

Open Doors

Open Doors
  • Author : Institute of International Education (New York, N.Y.)
  • Publisher :Unknown
  • Release Date :1992
  • Total pages :229
  • ISBN : UOM:39015077203167
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Summary :

Principles of Clinical Laboratory Utilization and Consultation

Principles of Clinical Laboratory Utilization and Consultation
  • Author : Brenta G. Davis,Diana Mass,Michael L. Bishop
  • Publisher :Unknown
  • Release Date :1999
  • Total pages :709
  • ISBN : UOM:39015046889179
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Summary : This resource provides laboratory managers and practitioners with detailed information on achieving cost-effective utilization of laboratory resources and enhancing diagnostic and therapeutic decision-making. Clinical chapters are organized by body system for ease of reference. Each disorder is discussed in terms of etiology, pathophysiology, clinical manifestations/syndrome, diagnostic testing strategies, and treatment with effects on laboratory results. Success stories and case studies illustrate each chapter's content. Abundant flow charts, tables, and algorithms clarify tests' selection, use, interpretation, and value. No other book on the market addresses these issues from the standpoint of the laboratorian. Introductory chapters address rationales and practical implementation strategies for improved clinical laboratory resource utilisation, as well as the skills needed to develop and apply a consultationapproach to laboratory management. Success stories illustrate ways in which laboratory manages have implemented cost effective laboratory resource utilisation programs and provide examples of the extraordinary cost savings and physician/laboratory collaboration that occur. Clinical chapters are organised by body system for ease of reference. The structure of these chapters parallels a physicians approach to medical problem-solvinghelping clinical laboratory personnel to better understand and meet physicians needs. Each disorder is discussed in terms of aetiology, pathophysiology, clinical manifestations/syndromes, diagnostic testing strategies, and appropriate treatment and their effects on lab results and further test choice. Abundant flow charts, tables, and algorithms clarify various tests selection, use, interpretation, and value. Case studies demonstrate the application of each chapters content within the context of realistic situations.

A Common Language for Postsecondary Accreditation

A Common Language for Postsecondary Accreditation
  • Author : Melodie E. Christal
  • Publisher :Unknown
  • Release Date :1985
  • Total pages :150
  • ISBN : PSU:000014595066
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Summary :

Clinical Laboratory Reference

Clinical Laboratory Reference
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2004
  • Total pages :229
  • ISBN : UOM:39015045499699
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Summary : Laboratory products and services currently available in the United States. Product information section arranged alphabetically by companies. Entries include description and ordering information. Indexes by manufactures; brand names; and test, equipment, and services. Product photograph section.

Employment Testing

Employment Testing
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :1989
  • Total pages :229
  • ISBN : IND:30000029600792
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Summary :

Gradwohl's Clinical Laboratory Methods and Diagnosis

Gradwohl's Clinical Laboratory Methods and Diagnosis
  • Author : Rutherford Birchard Hayes Gradwohl
  • Publisher :Unknown
  • Release Date :1980
  • Total pages :2540
  • ISBN : UOM:39015004401777
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Summary : Clinical shemistry. Hematology. Hemostasis and thrombosis. Immunohematology and tissue typing. Immunology. Bacteriology. Viral and rickettsial diagnostic procedures. Medical parasitology. Medical mycology. Serology of infectious diseases.

Deering's California Codes

Deering's California Codes
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2007
  • Total pages :229
  • ISBN : UCAL:B5032640
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Summary :

American Journal of Medical Technology

American Journal of Medical Technology
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :1981
  • Total pages :229
  • ISBN : UCLA:31158008531674
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Summary :

Saunders Manual of Clinical Laboratory Science

Saunders Manual of Clinical Laboratory Science
  • Author : Craig A. Lehmann
  • Publisher :Unknown
  • Release Date :1998
  • Total pages :1297
  • ISBN : UOM:39015041914543
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Summary : This major reference offers convenient, rapid access to essential guidance on all types of diagnostic testing performed in the clinical laboratory. It encompasses clinical hemostasis, chemistry, immunology, hematology, immunohematology, microbiology, coagulation, urinalysis, mycology, virology, and cytogenetics. Abundant charts, algorithms, bulleted lists, and subject headings complement brief, to-the-point passages of text to make information remarkably easy to find and easy to read.

Medical Laboratory Science

Medical Laboratory Science
  • Author : Anthony S-Y Leong
  • Publisher :Unknown
  • Release Date :1996
  • Total pages :172
  • ISBN : 0443053693
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Summary : This is a guide to basic histopathology for medical laboratory scientists in training and practice.

Minnesota Statutes

Minnesota Statutes
  • Author : Minnesota
  • Publisher :Unknown
  • Release Date :2012
  • Total pages :229
  • ISBN : MINN:31951D035408993
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Summary :

Effects of Disease on Clinical Laboratory Tests

Effects of Disease on Clinical Laboratory Tests
  • Author : Donald S. Young,Richard B. Friedman
  • Publisher :Unknown
  • Release Date :2001
  • Total pages :1918
  • ISBN : 189088345X
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Summary :