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An Introduction to Biological Membranes

An Introduction to Biological Membranes
  • Author : William Stillwell
  • Publisher :Unknown
  • Release Date :2013-04-20
  • Total pages :378
  • ISBN : 9780080931289
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Summary : An Introduction to Biological Membranes: From Bilayers to Rafts covers many aspects of membrane structure/function that bridges membrane biophysics and cell biology. Offering cohesive, foundational information, this publication is valuable for advanced undergraduate students, graduate students and membranologists who seek a broad overview of membrane science. Brings together different facets of membrane research in a universally understandable manner Emphasis on the historical development of the field Topics include membrane sugars, membrane models, membrane isolation methods, and membrane transport.

An Introduction to Biological Membranes

An Introduction to Biological Membranes
  • Author : William Stillwell
  • Publisher :Unknown
  • Release Date :2016-06-30
  • Total pages :590
  • ISBN : 9780444637901
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Summary : Introduction to Biological Membranes: Composition, Structure and Function, Second Edition is a greatly expanded revision of the first edition that integrates many aspects of complex biological membrane functions with their composition and structure. A single membrane is composed of hundreds of proteins and thousands of lipids, all in constant flux. Every aspect of membrane structural studies involves parameters that are very small and fast. Both size and time ranges are so vast that multiple instrumentations must be employed, often simultaneously. As a result, a variety of highly specialized and esoteric biochemical and biophysical methodologies are often utilized. This book addresses the salient features of membranes at the molecular level, offering cohesive, foundational information for advanced undergraduate students, graduate students, biochemists, and membranologists who seek a broad overview of membrane science. Significantly expanded coverage on function, composition, and structure Brings together complex aspects of membrane research in a universally understandable manner Features profiles of membrane pioneers detailing how contemporary studies originated Includes a timeline of important discoveries related to membrane science

Introduction to Biological Membranes

Introduction to Biological Membranes
  • Author : Mahendra Kumar Jain
  • Publisher :Unknown
  • Release Date :1988-01-18
  • Total pages :423
  • ISBN : UOM:39015012543040
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Summary : Covers the basic properties of biological membranes in terms of the underlying biophysical properties. Emphasizes the intrinsic molecular logic and intermolecular interactions that underly the functions of biomembranes. Chapter coverage includes a working model for the structure of a biomembrane, molecular properties of phospholipids in biomembranes, properties of lipid/water systems including polymorphism and phase properties, proteins and carbohydrates in bilayers, translocation across bilayers by solubility diffusion, transmembrane potential, and much more. Many recent developments are discussed, such as transbilayer conformation of proteins, single-channel conductance, the receptor mediated endocytosis, and others. Contains many tables, figures, and over 500 key references up to the end of 1986.

Biological Membranes

Biological Membranes
  • Author : Roger Harrison
  • Publisher :Unknown
  • Release Date :2013-11-22
  • Total pages :288
  • ISBN : 9789401168571
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Summary : to the Second Edition RESEARCH INTO MEMBRANE-ASSOCIATED PHENOMENA HAS EXPANDED VERY greatly in the five years that have elapsed since the first edition of Biological Membranes was published. It is to take account of rapid advances in the field that we have written the present edition. There is now general acceptance of the fluid mosaic model of membrane structure and of the chemiosmotic interpretation of energetic processes, and our attention has shifted from justifying these ideas to explaining membrane functions in their terms. Much more information has become available concerning the role of the plasma membrane in the cell's recognition of and response to external signals, and this is reflected in the increased coverage of these topics in the book. The general form of the book remains the same. As before, a list of suggested reading, sub-divided by chapter, is provided and this has been expanded to include a greater proportion of original papers. The book is still primarily designed as an advanced undergraduate text and also to serve as an introduction for post-graduate workers entering the field of membrane research. We have taken cognizance of the comments of many reviewers, colleagues and students on the first edition and thank them for their contributions. In particular we wish to acknowledge our colleagues R. Eisenthal, G. D. Holman, D. W. Hough, and A. H. Rose. Dr. C. R.

Characterization of Biological Membranes

Characterization of Biological Membranes
  • Author : Mu-Ping Nieh,Frederick A. Heberle,John Katsaras
  • Publisher :Unknown
  • Release Date :2019-07-22
  • Total pages :647
  • ISBN : 9783110544688
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Summary : The study of membranes has become of high importance in the fields of biology, pharmaceutical chemistry and medicine, since much of what happens in a cell or in a virus involves biological membranes. The current book is an excellent introduction to the area, which explains how modern analytical methods can be applied to study biological membranes and membrane proteins and the bioprocesses they are involved to.

Structure and Function of Biological Membranes

Structure and Function of Biological Membranes
  • Author : Lawrence I. Rothfield
  • Publisher :Unknown
  • Release Date :2014-06-28
  • Total pages :500
  • ISBN : 9781483281964
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Summary : Structure and Function of Biological Membranes explains the membrane phenomena at the molecular level through the use of biochemical and biophysical approaches. The book is an in-depth study of the structure and function of membranes. It is divided into three main parts. The first part provides an overview of the study of the biological membrane at the molecular level. Part II focuses on the detailed description of the overall molecular organization of membranes. The third part covers the relationship of the molecular organization of membranes to specific membrane functions; discusses catalytic membrane proteins; presents the role of membranes in important cellular functions; and looks at the membrane systems in eukaryotic cells. Biochemists, cell physiologists, biologists, researchers, and graduate and postdoctoral students in the field of biology will find the text a good reference material.

Biological Membranes in Toxicology

Biological Membranes in Toxicology
  • Author : E. C. Foulkes
  • Publisher :Unknown
  • Release Date :1998-12-17
  • Total pages :153
  • ISBN : 9781439806029
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Summary : Using this concise yet complete introduction to all aspects of biological membranes and their responses to toxicants, the reader will understand the role of cell membranes in controlling uptake, distribution, extrusion and excretion of toxic xenobiotics. The book also covers the historical background and critically evaluates some of the experimenta

The Physical Chemistry of MEMBRANES

The Physical Chemistry of MEMBRANES
  • Author : B. Silver
  • Publisher :Unknown
  • Release Date :2012-12-06
  • Total pages :336
  • ISBN : 9789401096287
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Summary : Ls book is an account of what physical chemistry h . . to say about the structural, electrical and transport properties of biological membranes and their simplest model-the lipid bilayer. The accent throughout is on basic ideas. In contrast to the essentially descriptive ap proach characteristic of texts on membrane biochemistry, our underlying themes are the role of force and entropy in maintaining membrane organization, in determining the electric fields and ionic environment of membranes, and in regulating the passage of molecules and ions across membranes. Although experimental findings will always be the touch stone against which theory will be tried, no attempt is made to present an exhaustive survey of experimental data. On the other hand, there is discussion of the nature and limitations of the results obtainable by the major laboratory techniques. The treatment is at the level of an advanced undergraduate course or an introductory survey suitable for post graduate students carrying out research in biochemistry, biophysics, or physiology. The mathematical demands on the reader are trivial. The few forbidding equations appearing in Chapter 7 are soon whittled away to simple practical expressions. Although the current-voltage characteristics of nerves are traditionally the province of biophysics rather than physical chemistry, certain aspects relevant to the electrical activity of nerves are nevertheless included in this text, namely, mem brane and diffusion potentials and conductivity fluctuations. Where rival theories exist, conflicting convictions have been presented, but not necessarily accorded equal approbation. The author has a viewpoint.

Physics of Biological Membranes

Physics of Biological Membranes
  • Author : Patricia Bassereau,Pierre Sens
  • Publisher :Unknown
  • Release Date :2018-12-30
  • Total pages :623
  • ISBN : 9783030006303
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Summary : This book mainly focuses on key aspects of biomembranes that have emerged over the past 15 years. It covers static and dynamic descriptions, as well as modeling for membrane organization and shape at the local and global (at the cell level) scale. It also discusses several new developments in non-equilibrium aspects that have not yet been covered elsewhere. Biological membranes are the seat of interactions between cells and the rest of the world, and internally, they are at the core of complex dynamic reorganizations and chemical reactions. Despite the long tradition of membrane research in biophysics, the physics of cell membranes as well as of biomimetic or synthetic membranes is a rapidly developing field. Though successful books have already been published on this topic over the past decades, none include the most recent advances. Additionally, in this domain, the traditional distinction between biological and physical approaches tends to blur. This book gathers the most recent advances in this area, and will benefit biologists and physicists alike.

Ion Transport through Biological Membranes

Ion Transport through Biological Membranes
  • Author : M.C. Mackey
  • Publisher :Unknown
  • Release Date :2013-03-13
  • Total pages :242
  • ISBN : 9783642810084
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Summary : This book illustrates some of the ways physics and mathematics have been, and are being, used to elucidate the underlying mechan isms of passive ion movement through biological membranes in general, and the membranes of excltable cells in particular. I have made no effort to be comprehensive in my introduction of biological material and the reader interested in a brief account of single cell electro physlology from a physically-oriented biologists viewpoint will find the chapters by Woodbury (1965) an excellent introduction. Part I is introductory in nature, exploring the basic electrical properties of inexcitable and excitable cell plasma membranes. Cable theory is utilized to illustrate the function of the non-decrementing action potential as a signaling mechanism for the long range trans mission of information in the nervous system, and to gain some in sight into the gross behaviour of neurons. The detailed analysis of Hodgkin and Huxley on the squid giant axon membrane ionic conductance properties is reviewed briefly, and some facets of membrane behaviour that have been revealed since the appearance of their work are dis cussed. Part II examines the foundations of electrodiffusion theory, and the use of that theory in trying to develop quantitative expla nationsof the observed membrane properties of excitable cells, in particular the squid giant axon. In addition, an ad hoc formulation of electrodiffusion theory including active transport is presented to illustrate the qualitative nature of cellular homeostasis with respect to intracellular ionic concentrations and membrane potential, and cellular responses to prolonged stimUlation.

The Membranes of Cells

The Membranes of Cells
  • Author : Philip Yeagle
  • Publisher :Unknown
  • Release Date :1993
  • Total pages :349
  • ISBN : UOM:39015026979164
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Summary : In this new edition of The Membranes of Cells, all of the chapters have been updated, some have been completely rewritten, and a new chapter on receptors has been added. The book has been designed to provide both the student and researcher with a synthesis of information from a number of scientific disciplines to create a comprehensive view of the structure and function of the membranes of cells. The topics are treated in sufficient depth to provide an entry point to the more detailed literature needed by the researcher. Key Features * Introduces biologists to membrane structure and physical chemistry * Introduces biophysicists to biological membrane function * Provides a comprehensive view of cell membranes to students, either as a necessary background for other specialized disciplines or as an entry into the field of biological membrane research * Clarifies ambiguities in the field

Structure and Dynamics of Membranes

Structure and Dynamics of Membranes
  • Author : R. Lipowsky,E. Sackmann
  • Publisher :Unknown
  • Release Date :1995-06-15
  • Total pages :1052
  • ISBN : 0080541917
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Summary : The first volume of the Handbook deals with the amazing world of biomembranes and lipid bilayers. Part A describes all aspects related to the morphology of these membranes, beginning with the complex architecture of biomembranes, continues with a description of the bizarre morphology of lipid bilayers and concludes with technological applications of these membranes. The first two chapters deal with biomembranes, providing an introduction to the membranes of eucaryotes and a description of the evolution of membranes. The following chapters are concerned with different aspects of lipids including the physical properties of model membranes composed of lipid-protein mixtures, lateral phase separation of lipids and proteins and measurement of lipid-protein bilayer diffusion. Other chapters deal with the flexibility of fluid bilayers, the closure of bilayers into vesicles which attain a large variety of different shapes, and applications of lipid vesicles and liposomes. Part B covers membrane adhesion, membrane fusion and the interaction of biomembranes with polymer networks such as the cytoskeleton. The first two chapters of this part discuss the generic interactions of membranes from the conceptual point of view. The following two chapters summarize the experimental work on two different bilayer systems. The next chapter deals with the process of contact formation, focal bounding and macroscopic contacts between cells. The cytoskeleton within eucaryotic cells consists of a network of relatively stiff filaments of which three different types of filaments have been identified. As explained in the next chapter much has been recently learned about the interaction of these filaments with the cell membrane. The final two chapters deal with membrane fusion.

Cell Membranes

Cell Membranes
  • Author : Lukas Buehler
  • Publisher :Unknown
  • Release Date :2015-06-17
  • Total pages :400
  • ISBN : 9781317335603
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Summary : Cell Membranes offers a solid foundation for understanding the structure and function of biological membranes. The book explores the composition and dynamics of cell membranes discussing the molecular and biological diversity of its lipid and protein components and how the combinatorial richness of both components explains the chemical, mechanical,

Permeability of Biological Membranes

Permeability of Biological Membranes
  • Author : Gaspar Banfalvi
  • Publisher :Unknown
  • Release Date :2016-02-10
  • Total pages :263
  • ISBN : 9783319280981
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Summary : This book deals with biological membranes, focuses on permeabilization and pays particular attention to reversible permeabilization to maintain the viability and physiological conditions of the cells. Selective permeability of biological membranes also known as semipermeability, partial permeability or differential permeability allows molecules to diffuse, pass by passive and active or by other types of transport processes mediated by proteins. The first chapter of the book deals with the composition of biological membranes, characterizes cellular membranes of prokaryotic, eukaryotic cells, membranes of cellular organelles and the function of biological membranes. The second chapter provides an overview of bilayer permeability, selectivity of permeabilization and cellular transport processes. Chapter 3 overviews different cell manipulations that aim to make cells permeable while maintaining not only the structural but also the functional integrity of cells. The last chapter deals with applications, particularly with reversible permeabilization to study macromolecular (DNA, RNA, poly-ADP ribose) biosynthetic processes, replication, gene expression, visualization of replicons, intermediates of chromosome condensation, genotoxic chromatin changes, upon treatment with heavy metals and different types of irradiation. The interdisciplinary aspects of the book contribute to the understanding of the structure of nucleic acids, replicative intermediates, Okazaki fragments, RNA primer mechanism, subphases of replication and repair synthesis, replicons, gene expression, chromosome condensation generated a wealth of information that will attract a wide readership. The natural audience engaged in DNA research, including genetics, cell and molecular biology, chemistry, biochemistry, medicine, pharmacy will find essential material in the book.

Energy Transduction in Biological Membranes

Energy Transduction in Biological Membranes
  • Author : William A. Cramer,David B. Knaff
  • Publisher :Unknown
  • Release Date :2012-12-06
  • Total pages :579
  • ISBN : 9781461232209
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Summary : Energy Transduction in Biological Membranes was primarily designed for graduate courses in bioenergetics. Not only does it discuss basic principles and concepts central to modern membrane biochemistry, biophysics and molecular biology, but also (1) the components and pathways for electron transport and hydrogen ion translocation, and (2) the utilization of electrochemical ion gradients. The book is unique in presenting a comparative treatment of respiratory and photosynthetic energy transduction, and in using protein sequence data coupled with physical concepts to discuss the mechanisms of energy transducing proteins.

Thermal Biophysics of Membranes

Thermal Biophysics of Membranes
  • Author : Thomas Heimburg
  • Publisher :Unknown
  • Release Date :2008-02-08
  • Total pages :378
  • ISBN : 9783527611607
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Summary : An overview of recent experimental and theoretical developments in the field of the physics of membranes, including new insights from the past decade. The author uses classical thermal physics and physical chemistry to explain our current understanding of the membrane. He looks at domain and 'raft' formation, and discusses it in the context of thermal fluctuations that express themselves in heat capacity and elastic constants. Further topics are lipid-protein interactions, protein binding, and the effect of sterols and anesthetics. Many seemingly unrelated properties of membranes are shown to be intimately intertwined, leading for instance to a coupling between membrane state, domain formation and vesicular shape. This also applies to non-equilibrium phenomena like the propagation of density pulses during nerve activity. Also included is a discussion of the application of computer simulations on membranes. For both students and researchers of biophysics, biochemistry, physical chemistry, and soft matter physics.

Membrane Structural Biology

Membrane Structural Biology
  • Author : Mary Luckey
  • Publisher :Unknown
  • Release Date :2008-03-17
  • Total pages :229
  • ISBN : 9781107079694
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Summary : Membrane Structural Biology brings together a physicochemical analysis of the membrane with the latest structural biology on membrane lipids and proteins to offer an exciting portrayal of biomembranes. Written with remarkable clarity, this text appears at a time when membranes have moved back into the scientific spotlight and will provide a unique foundation for advanced students and working scientists. The structure, function, and biogenesis of membrane lipids and proteins are examined, bioinformatics and computational approaches to membrane components are introduced, and the high-resolution structures that are giving new insights into the vital roles membranes play are discussed. The many correlations between membrane research and human health are discussed and key themes for future work in this area are identified. Membrane structural biology is poised to answer many basic and applied questions and this cutting-edge text will provide a solid grounding for all those working in this field.

Transport And Diffusion Across Cell Membranes

Transport And Diffusion Across Cell Membranes
  • Author : Wilfred Stein
  • Publisher :Unknown
  • Release Date :2012-12-02
  • Total pages :704
  • ISBN : 9780323143202
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Summary : Transport and Diffusion across Cell Membranes is a comprehensive treatment of the transport and diffusion of molecules and ions across cell membranes. This book shows that the same kinetic equations (with appropriate modification) can describe all the specialized membrane transport systems: the pores, the carriers, and the two classes of pumps. The kinetic formalism is developed step by step and the features that make a system effective in carrying out its biological role are highlighted. This book is organized into six chapters and begins with an introduction to the structure and dynamics of cell membranes, followed by a discussion on how the membrane acts as a barrier to the transmembrane diffusion of molecules and ions. The following chapters focus on the role of the membrane's protein components in facilitating transmembrane diffusion of specific molecules and ions, measurements of diffusion through pores and the kinetics of diffusion, and the structure of such pores and their biological regulation. This book methodically introduces the reader to the carriers of cell membranes, the kinetics of facilitated diffusion, and cotransport systems. The primary active transport systems are considered, emphasizing the pumping of an ion (sodium, potassium, calcium, or proton) against its electrochemical gradient during the coupled progress of a chemical reaction while a conformational change of the pump enzyme takes place. This book is of interest to advanced undergraduate students, as well as to graduate students and researchers in biochemistry, physiology, pharmacology, and biophysics.

Fluorescent Methods to Study Biological Membranes

Fluorescent Methods to Study Biological Membranes
  • Author : Yves Mely,Guy Duportail
  • Publisher :Unknown
  • Release Date :2012-10-10
  • Total pages :486
  • ISBN : 9783642331275
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Summary : Biological membranes play a central role in cell structure, shape and functions. However, investigating the membrane bilayer has proved to be difficult due to its highly dynamic and anisotropic structure, which generates steep gradients at the nanometer scale. Due to the decisive impact of recently developed fluorescence-based techniques, tremendous advances have been made in the last few years in our understanding of membrane characteristics and functions. In this context, the present book illustrates some of these major advances by collecting review articles written by highly respected experts. The book is organized in three parts, the first of which deals with membrane probes and model membranes. The second part describes the use of advanced quantitative and high-resolution techniques to explore the properties of biological membranes, illustrating the key progress made regarding membrane organization, dynamics and interactions. The third part is focused on the investigation of membrane proteins using the same techniques, and notably on the membrane receptors that play a central role in signaling pathways and therapeutic strategies. All chapters provide comprehensive information on membranes and their exploration for beginners in the field and advanced researchers alike.

Cell Biology by the Numbers

Cell Biology by the Numbers
  • Author : Ron Milo,Rob Phillips
  • Publisher :Unknown
  • Release Date :2015-12-07
  • Total pages :400
  • ISBN : 9781317230694
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Summary : A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid

Concepts of Biology

Concepts of Biology
  • Author : Samantha Fowler,Rebecca Roush,James Wise
  • Publisher :Unknown
  • Release Date :2018-01-07
  • Total pages :618
  • ISBN : 9888407457
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Summary : Concepts of Biology is designed for the single-semester introduction to biology course for non-science majors, which for many students is their only college-level science course. As such, this course represents an important opportunity for students to develop the necessary knowledge, tools, and skills to make informed decisions as they continue with their lives. Rather than being mired down with facts and vocabulary, the typical non-science major student needs information presented in a way that is easy to read and understand. Even more importantly, the content should be meaningful. Students do much better when they understand why biology is relevant to their everyday lives. For these reasons, Concepts of Biology is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand.We also strive to show the interconnectedness of topics within this extremely broad discipline. In order to meet the needs of today's instructors and students, we maintain the overall organization and coverage found in most syllabi for this course. A strength of Concepts of Biology is that instructors can customize the book, adapting it to the approach that works best in their classroom. Concepts of Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand--and apply--key concepts.