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Atlas of Zebrafish Development

Atlas of Zebrafish Development
  • Author : Robert Bryson-Richardson,Silke Berger,Peter Currie
  • Publisher :Unknown
  • Release Date :2012
  • Total pages :232
  • ISBN : 9780123740168
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Summary : Zebrafish are widely considered an excellent model system for vertebrate development. The embryo is transparent, thereby enabling visualization and use of labelling and transgenic approaches. Moreover, because of the ease of inducing new mutations in zebrafish and similarity with the human genome, this organism may be used effectively for disease studies. For example, mutant zebrafish are being utilized for testing drugs that will combat a range of human diseases, from Alzheimer's and cancer to kidney failure and congenital heart disease. For the first time, this atlas provides the research community with a complete reference for zebrafish anatomy spanning the early embryo all the way to adulthood. The authors employ the technique of optical projection tomography (OPT), and offer a series of sections in multiple planes from each sample. The contents are organized by developmental stages, with over 200 images that contain annotations describing anatomical structures relevant to development. In addition, chapters feature explanatory text that highlights major developments in the zebrafish during each stage. * Provides the first comprehensive anatomical resource that covers all regions of zebrafish anatomy from the larval period to adulthood. * The over 200 images include explanatory notes * Each chapter contains a concise description of key anatomical features that factor in zebrafish development * Despite many years of use as a model system, until now there has never been a guide to zebrafish at the larval stage. * The book's website contains a database of over 10k sections from different regions as well as 3D images that are interactive.

Atlas of Early Zebrafish Brain Development

Atlas of Early Zebrafish Brain Development
  • Author : Dr. Thomas Mueller,Mario Wullimann
  • Publisher :Unknown
  • Release Date :2015-11-18
  • Total pages :258
  • ISBN : 9780124172869
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Summary : Atlas of Early Zebrafish Brain Development: A Tool for Molecular Neurogenetics, Second Edition, remains the only neuroanatomical expression atlas of important genetic and immunohistochemical markers of this vertebrate model system. It represents a key reference and interpretation matrix for analyzing expression domains of genes involved in Zebrafish brain development and neurogenesis, and serves as a continuing milestone in this research area. This updated volume provides in-situ hybridized and immunostained preparations of complete series of brain sections, revealing markers of the fundamental stages in the life history of neuronal cells in very high quality preparations and photographic plates. Specific additions to this edition include documentation on the distribution of neurons expressing GABA, dopamine and serotonin, material on the basal ganglia, hypothalamus, and the caudal, segmented part of the diencephalon, new theories on the early organization of the telencephalon and thalamus, and integration of a comparative perspective on the mid- and hindbrain. Documentation on the distribution of neurons expressing GABA, dopamine and serotonin Material on the basal ganglia, hypothalamus, and the caudal, segmented part of the diencephalon New theories about the early organization of the telencephalon and thalamus Integration of a comparative perspective on the mid- and hindbrain

Atlas of Early Zebrafish Brain Development

Atlas of Early Zebrafish Brain Development
  • Author : Thomas Mueller,Mario F. Wullimann
  • Publisher :Unknown
  • Release Date :2005-08-22
  • Total pages :183
  • ISBN : 0444517383
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Summary : The zebrafish has become the standard model for the study of the development of the brain in vertebrates. Molecular biologists, developmental biologists, and neuroscientists increasingly turn to this fish with it's now wide variety of available mutants and known marker genes. This book is intended as a basic handbook and guideline for zebrafish researchers who seek to understand early brain development and neurogenesis in this important model system. The book introduces the reader to the field and principles of vertebrate brain development and neurogenesis as it is commonly investigated in other model organisms such as frog, chick and mouse. With its holistic and broad approach, the atlas is not only recommended for zebrafish researchers working on specific questions of developmental neurogenetics, but also for students at progressed levels who enter the young and exciting field of zebrafish developmental neurogenetics. There is simply no alternative source for combined neuroanatomical and gene expression data in the zebrafish on this level of detail. * Stands as the first gene-expression based developmental atlas in any neurogenetic model system * Provides comparative context to other model systems * Includes many explanatory schematics in uniform style and color coding

Behavioral and Neural Genetics of Zebrafish

Behavioral and Neural Genetics of Zebrafish
  • Author : Robert T. Gerlai
  • Publisher :Unknown
  • Release Date :2020-04-03
  • Total pages :614
  • ISBN : 9780128175293
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Summary : Behavioral and Neural Genetics of Zebrafish assembles the state-of-the-art methodologies and current concepts pertinent to their neurobehavioral genetics. Discussing their natural behavior, motor function, learning and memory, this book focuses on the fry and adult zebrafish, featuring a comprehensive account of modern genetic and neural methods adapted to, or specifically developed for, Danio rerio. Numerous examples of how these behavioral methods may be utilized for disease models using the zebrafish are presented, as is a section on bioinformatics and "big-data" related questions. Provides the most comprehensive snapshot of the fast-evolving zebrafish neurobehavior genetics field Describes behavioral, genetic and neural methods and concepts for use in adult and larval zebrafish Features examples of zebrafish models of human central nervous system disorders Discusses bioinformatics questions pertinent to zebrafish neurobehavioral genetics

Neuroanatomy of the Zebrafish Brain

Neuroanatomy of the Zebrafish Brain
  • Author : Mario F. Wulliman,Barbara Rupp,Heinrich Reichert
  • Publisher :Unknown
  • Release Date :2012-12-06
  • Total pages :156
  • ISBN : 9783034889797
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Summary :

Vascular Development

Vascular Development
  • Author : Derek J. Chadwick,Jamie A. Goode
  • Publisher :Unknown
  • Release Date :2007-08-20
  • Total pages :260
  • ISBN : 9780470319420
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Summary : The formation of blood vessels is an essential aspect of embryogenesis in vertebrates. It is a central feature of numerous post-embryonic processes, including tissue and organ growth and regeneration. It is also part of the pathology of tumour formation and certain inflammatory conditions. In recent years, comprehension of the molecular genetics of blood vessel formation has progressed enormously and studies in vertebrate model systems, especially the mouse and the zebrafish, have identified a common set of molecules and processes that are conserved throughout vertebrate embryogenesis while, in addition, highlighting aspects that may differ between different animal groups. The discovery in the past decade of the crucial role of new blood vessel formation for the development of cancers has generated great interest in angiogenesis (the formation of new blood vessels from pre-existing ones), with its major implications for potential cancer-control strategies. In addition, there are numerous situations where therapeutic treatments either require or would be assisted by vasculogenesis (the de novo formation of blood vessels). In particular, post-stroke therapies could include treatments that stimulate neovascularization of the affected tissues. The development of such treatments, however, requires thoroughly understanding the developmental properties of endothelial cells and the basic biology of blood vessel formation. While there are many books on angiogenesis, this unique book focuses on exactly this basic biology and explores blood vessel formation in connection with tissue development in a range of animal models. It includes detailed discussions of relevant cell biology, genetics and embryogenesis of blood vessel formation and presents insights into the cross-talk between developing blood vessels and other tissues. With contributions from vascular biologists, cell biologists and developmental biologists, a comprehensive and highly interdisciplinary volume is the outcome.

The Atlas of Mouse Development

The Atlas of Mouse Development
  • Author : Matthew H. Kaufman
  • Publisher :Unknown
  • Release Date :1992-09-15
  • Total pages :512
  • ISBN : UOM:39015020863133
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Summary : Not since the early 1970s has there been an attempt to describe and illustrate the anatomy of the developing mouse embryo. More than ever such material is needed by biologists as they begin to unravel the molecular mechanisms underlying development and differentiation. After more than ten years of painstaking work, Matt Kaufman has completed The Atlas of Mouse Development--the definitive account of mouse embryology and development. For all those researching or studying mammalian development, The Atlas of Mouse Development will be the standard reference work for many years to come. Provides a comprehensive sequential account of the development of the mouse from pre-implantation to term Contains clear and concise descriptions of the anatomical features relevant to each stage of development Large format for easy use Contains explanatory notes and legends, and more than 180 meticulously labeled plates, 1,300 photographs of individual histological sections, and 200 electron micrographs, illustrating: Intermittent serial histological sections through embryos throughout embryogenesis and organogenesis Differentiation of specific organs and organ systems, including the spinal cord, eyes, gonads, kidneys, lungs and skeletal system External appearance of intact embryos throughout development

Development and Engineering of Dopamine Neurons

Development and Engineering of Dopamine Neurons
  • Author : Jeroen Pasterkamp,Marten P. Smidt,J. Peter H. Burbach
  • Publisher :Unknown
  • Release Date :2009-12-16
  • Total pages :127
  • ISBN : 1441903224
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Summary : Theneurotransmitter dopamine has just celebrated its 50thbirthday. The discovery of dopamine as a neuronal entity in the late 1950s and the notion that it serves in neurotransmission has been a milestone in the field of neuroscience research. This milestone marked the beginning of an era that explored the brain as an integrated collection of neuronal systems that one could distinguish on basis of neurotransm- ter identities, and importantly, in which one started to be able to pinpoint the seat of brain disease. The mesodiencephalic dopaminergic (mdDA) system, previously designated as midbraindopaminergic system, has received much attention since its discovery. The initial identification of dopamine as a neurotransmitter in the central nervous system (CNS) and its relevance to psychiatric and neurological disorders have stimulated a plethora of neurochemical, pharmacological and genetic studies into the function of dopamine neurons and theirprojections. In the last decade, studies on gene expression and development have further increased the knowledge of this neuronal population and have unmasked a new level of complexity. The start of the molecular dissection of the mdDA system has been marked by the cloning and characterization ofNurrl and Pitx3. These transcription factors were shown to have a critical function during mdDA development. These initial studies have been followed by the identification of many other proteins, which have a crucial function in the creation of a dopamine neuron permissive region, induction of precursors, induction of terminaldifferent- tion and finally maintenance of the mdDA neuronal pool.

Craniofacial Development

Craniofacial Development
  • Author : British Society for Developmental Biology. Meeting
  • Publisher :Unknown
  • Release Date :1988
  • Total pages :257
  • ISBN : UOM:39015013802106
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Summary :

Scientific Frontiers in Developmental Toxicology and Risk Assessment

Scientific Frontiers in Developmental Toxicology and Risk Assessment
  • Author : National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Board on Environmental Studies and Toxicology,Committee on Developmental Toxicology
  • Publisher :Unknown
  • Release Date :2000-12-21
  • Total pages :354
  • ISBN : 9780309070867
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Summary : Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.

Fish Development and Genetics

Fish Development and Genetics
  • Author : Gong Zhiyuan,Vladimir Korzh
  • Publisher :Unknown
  • Release Date :2004-11-02
  • Total pages :688
  • ISBN : 9789814482851
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Summary : The zebrafish is the most important fish model in developmental and genetic analyses. This book contains 19 review articles covering a broad spectrum of topics, from development to genetic tools. The contents range from early development, the role of maternal factors and gastrulation, to tissue differentiation and organogenesis, such as development of the organizer, notochord, floor plate, nervous system, somites, muscle, skeleton and endoderm. The genetic tools cover morpholino knock-down, transgenics, fish cloning, transposons and genome evolution. The book also includes two chapters on genome mapping and embryonic stem cells in medaka, another important model fish. Summarizing the state-of-the-art studies of the zebrafish model and focusing on the molecular aspects of development, this book is a valuable reference for students learning the basic aspects of the zebrafish model, and for researchers seeking resources in zebrafish research. Contents:The Role of Maternal Factors in Early Zebrafish Development (F Pelegri)Gastrulation in Zebrafish (F Ulrich & C-P Heisenberg)Development of the Zebrafish Organiser and Notochord (K A Thomas & D L Stemple)Formation and Functions of the Floor Plate (J Tian & K Sampath)Form and Function in the Zebrafish Nervous System (M Hendricks & S Jesuthasan)Development of the Primary Nervous System of the Zebrafish Embryo (U Strähle & V Korzh)Making Scents: Development and Function of the Olfactory Sensory System (K E Whitlock)Somites Segmentation: A View from Fish (H Takeda & Y Saga)Vertebrate Somite Development, Notch Signaling and Others (Y-J Jiang)Molecular Regulation of Fish Muscle Development and Growth (S J Du)Skeletogenesis in Zebrafish Danio rerio: Evolutionary and Developmental Aspects (S Fisher & P M Mabee)Endoderm Formation in Zebrafish (N B David et al.)Gene 'Knockdown' Approaches Using Unconventional Antisense Oligonucleotides (E Chen et al.)Transgenic Fish for Developmental Biology Studies (Z-Y Gong et al.)Cloning the Zebrafish (B Ju et al.)Applications of Transponsable Elements in Fish for Transgenesis and Functional Genomics (P B Hacketts et al.)Evolution of the Zebrafish Genome (J H Postlethwait)Medaka Genome Mappling for Functional Genomics (H Mitani et al.)Medaka Embryonic Stem Cells (Y-H Hong & M Schartl) Readership: Upper level undergraduates, graduate students, academics and researchers in cell & molecular biology, fish & marine biology and genetics. Keywords:Zebrafish;Medaka;Embrynonic Development;Axial Structures;Neurogenesis;Somites;Transgenics;GenomeKey Features:Contributed by active researchers working in the field of developmental biology of the zebrafish and medakaCovers essentially all major topics from early development to organogenesis as well as several most important genetic toolsRepresents most updated reviews in selected areas of the rapidly developing field

Kaufman’s Atlas of Mouse Development Supplement

Kaufman’s Atlas of Mouse Development Supplement
  • Author : Richard Baldock,Jonathan Bard,Duncan Davidson,Gillian Morriss-Kay
  • Publisher :Unknown
  • Release Date :2015-09-23
  • Total pages :344
  • ISBN : 9780128009130
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Summary : Kaufman's Atlas of Mouse Development: With Coronal Sections continues the stellar reputation of the original Atlas by providing updated, in-depth anatomical content and morphological views of organ systems.The publication offers written descriptions of the developmental origins of the organ systems alongside high-resolution images for needed visualization of developmental processes. Matt Kaufman himself has annotated the coronal images in the same clear, meticulous style of the original Atlas. Kaufman's Atlas of Mouse Development: With Coronal Sections follows the original Atlas as a continuation of the standard in the field for developmental biologists and researchers across biological and biomedical sciences studying mouse development. Provides high-resolution images for best visualization of key developmental processes and structures Offers in-depth anatomy and morphological views of organ systems Written descriptions convey developmental origins of the organ systems

The Zebrafish in Biomedical Research

The Zebrafish in Biomedical Research
  • Author : Samuel Cartner,Judith S. Eisen,Susan F. Farmer,Karen J. Guillemin,Michael L. Kent,George E. Sanders
  • Publisher :Unknown
  • Release Date :2019-11-22
  • Total pages :718
  • ISBN : 9780128124321
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Summary : The Zebrafish in Biomedical Research: Biology, Husbandry, Diseases, and Research Applications is a comprehensive work that fulfills a critical need for a thorough compilation of information on this species. The text provides significant updates for working vivarium professionals maintaining zebrafish colonies, veterinarians responsible for their care and well-being, zoologists and ethologists studying the species, and investigators using the species to gain critical insights into human physiology and disease. As the zebrafish has become an important model organism for the study of vertebrate development and disease, organ function, behavior, toxicology, cancer, and drug discovery, this book presents an important resource for future research. Presents a complete view of the zebrafish, covering their biology, husbandry, diseases and research applications Includes the work of world-renowned authors Provides the first authoritative and comprehensive treatment of zebrafish in biomedical research as part of the ACLAM series

Neuronal Nicotinic Receptors

Neuronal Nicotinic Receptors
  • Author : F. Clementi,D. Fornasari,C. Gotti
  • Publisher :Unknown
  • Release Date :2012-12-06
  • Total pages :821
  • ISBN : 9783642570797
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Summary : Neuronal nicotinic receptors are key molecules for signal transduction in a number of neuronal pathways. They are widely distributed in the brain and are known to be involved in cognitive tasks, including learning and memory, in smoking addiction and in several brain diseases, such as Alzheimer's and Parkinson's dementias, schizophrenia, and epilepsy. This book provides a comprehensive review of the field, starting with a historical perspective and dealing with the molecular structure of these receptors, their biophysical and pharmacological properties, their distribution in central and peripheral nervous systems, and their major involvement in brain functions. Particular emphasis is paid to drugs (both new and old) that are useful in the diagnosis and treatment of diseases involving neuronal nicotinic receptors. Finally, the relevance of these receptors in smoking addiction is carefully evaluated, together with future trends and the latest results.

Embryos

Embryos
  • Author : Jonathan Bard
  • Publisher :Unknown
  • Release Date :1994
  • Total pages :224
  • ISBN : UOM:39015032486063
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Summary : In this highly illustrated atlas, a group of internationally known authors review the development and significance of Arabidopsis, Dictyostelium discoideum, sea urchin, nematode worm, mollusc, leech, Drosophila, fish, toad, chick, mouse and human.

Fish Larval Physiology

Fish Larval Physiology
  • Author : Roderick Nigel Finn
  • Publisher :Unknown
  • Release Date :2020-04-30
  • Total pages :742
  • ISBN : 9781439842775
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Summary : This book is intended as a resource for students and researchers interested in developmental biology and physiology and specifically addresses the larval stages of fish. Fish larvae (and fish embryos) are not small juveniles or adults. Rather they are transitionary organisms that bridge the critical gap between the singlecelled egg and sexually immature juvenile. Fish larvae represent the stage of the life cycle that is used for differentiation, feeding and distribution. The book aims at providing a single-volume treatise that explains how fish larvae develop and differentiate, how they regulate salt, water and acid-base balance, how they transport and exchange gases, acquire and utilise energy, how they sense their environment, and move in their aquatic medium, how they control and defend themselves, and finally how they grow up.

Zebrafish

Zebrafish
  • Author : Christiane Nusslein-Volhard,Ralf Dahm
  • Publisher :Unknown
  • Release Date :2002-09-19
  • Total pages :303
  • ISBN : 019963808X
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Summary : The zebrafish has become one of the most important model organisms to study biologial processes in vivo. As a vertebrate that has many of the strengths of invertebrate model systems, it offers numerous advantages to researchers interested in many aspects of embryonic development, physiology and disease. The next few years will see the completion of large scale initiatives that exploit the zebrafish as a model system for the understanding of gene function in vertebrates, including the sequencing of the genome. The zebrafish will therefore play an increasingly important role in the future of biomedical research. Whole genome sequencing projects, such as the human genome project, have led to the isolation of tens of thousands of genes for which the in vivo function is unknown. It is therefore likely that an increasing number of researchers will turn to organisms such as the zebrafish to understand the in vivo requirement for the proteins these genes encode. Recent technical advances now allow the rapid testing of in vivo function of as yet uncharacterised genes in zebrafish in large numbers and at a speed that is impossible in other systems. This book not only provides a complete set of instructions that will allow researchers to establish the zebrafish in their laboratory. It also gives a broad overview of commonly used methods and a comprehensive collection of protocols describing the most powerful techniques.

Functional Analysis of Chemokine Signaling in Zebrafish Development

Functional Analysis of Chemokine Signaling in Zebrafish Development
  • Author : Qin Li
  • Publisher :Unknown
  • Release Date :2004
  • Total pages :229
  • ISBN : UOM:39015059185929
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Summary :

Molecular Imaging

Molecular Imaging
  • Author : Ralph Weissleder
  • Publisher :Unknown
  • Release Date :2010
  • Total pages :1357
  • ISBN : 1607950057
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Summary : The field of molecular imaging of living subjects have evolved considerably and have seen spectacular advances in chemistry, engineering and biomedical applications. This textbook was designed to fill the need for an authoritative source for this multi-disciplinary field. We have been fortunate to recruit over 80 leading authors contributing 75 individual chapters. Given the multidisciplinary nature of the field, the book is broken into six different sections: "Molecular Imaging technologies", "Chemistry", "Molecular Imaging in Cell and Molecular Biology", "Applications of Molecular Imaging", "Molecular Imaging in Drug Evaluation" with the final section comprised of chapters on computation, bioinformatics and modeling. The organization of this large amount of information is logical and strives to avoid redundancies among chapters. It encourages the use of figures to illustrate concepts and to provide numerous molecular imaging examples.

Chemical Anatomy of the Zebrafish Retina

Chemical Anatomy of the Zebrafish Retina
  • Author : Stephen Yazulla,Keith M. Studholme,Robert E. Marc,David Cameron
  • Publisher :Unknown
  • Release Date :2012-12-06
  • Total pages :106
  • ISBN : 9781461510895
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Summary : General introduction.- Neurochemical anatomy of the zebrafish retina as determined by immunocytochemistry.- A molecular phenotype atlas of the zebrafish retina.

Atlas of Drosophila Development

Atlas of Drosophila Development
  • Author : Volker Hartenstein
  • Publisher :Unknown
  • Release Date :1993
  • Total pages :57
  • ISBN : UOM:39015029119297
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Summary : This full-color atlas graphically documents the main events of embryonic and post-embryonic development in Drosophila. Schematic surface views and transverse sections from several developmental stages are shown for the individual organs such as gut, nervous system, epidermis and musculature. By combining camera lucida tracing with digital technology, Volker Hartenstein has created a unique, beautiful and convenient reference book that will interest all developmental biologists.