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• Author : Vladimir Uversky,Yuri Lyubchenko
• Publisher :Unknown
• Release Date :2013-11-05
• Total pages :552
• ISBN : 9780123978219

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Summary : Bio-Nanoimaging: Protein Misfolding & Aggregation provides a unique introduction to both novel and established nanoimaging techniques for visualization and characterization of misfolded and aggregated protein species. The book is divided into three sections covering: - Nanotechnology and nanoimaging technology, including cryoelectron microscopy of beta(2)-microglobulin, studying amyloidogensis by FRET; and scanning tunneling microscopy of protein deposits - Polymorphisms of protein misfolded and aggregated species, including fibrillar polymorphism, amyloid-like protofibrils, and insulin oligomers - Polymorphisms of misfolding and aggregation processes, including multiple pathways of lysozyme aggregation, misfolded intermediate of a PDZ domain, and micelle formation by human islet amyloid polypeptide Protein misfolding and aggregation is a fast-growing frontier in molecular medicine and protein chemistry. Related disorders include cataracts, arthritis, cystic fibrosis, late-onset diabetes mellitus, and numerous neurodegenerative diseases like Alzheimer's and Parkinson's. Nanoimaging technology has proved crucial in understanding protein-misfolding pathologies and in potential drug design aimed at the inhibition or reversal of protein aggregation. Using these technologies, researchers can monitor the aggregation process, visualize protein aggregates and analyze their properties. Provides practical examples of nanoimaging research from leading molecular biology, cell biology, protein chemistry, biotechnology, genetics, and pharmaceutical labs Includes over 200 color images to illustrate the power of various nanoimaging technologies Focuses on nanoimaging techniques applied to protein misfolding and aggregation in molecular medicine

• Author : Beth A. Goins,William T. Phillips
• Publisher :Unknown
• Release Date :2011-09-07
• Total pages :350
• ISBN : 9789814267915

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Summary : The first resource of its kind, this book covers cutting-edge research on the use of nanoparticles for in vivo diagnostic medical imaging and therapy. It discusses a variety of nanoparticles, including quantum dots, carbon nanotubes, dendrimers, gold nanoshells, metal nanorods, micelles, liposomes, polymers, MRI iron oxide particles, and microbubbles. Examples in the book include multifunctional nanoparticles that designed for multimodality imaging and simultaneous diagnostic and therapy (theranostic) applications.

• Author : D. Anselmetti
• Publisher :Unknown
• Release Date :2004
• Total pages :132
• ISBN : UOM:39015059126857

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Summary : Proceedings of SPIE present the original research papers presented at SPIE conferences and other high-quality conferences in the broad-ranging fields of optics and photonics. These books provide prompt access to the latest innovations in research and technology in their respective fields. Proceedings of SPIE are among the most cited references in patent literature.

• Author : Zhe Liu
• Publisher :Unknown
• Release Date :2018-09-01
• Total pages :117
• ISBN : 9789811048043

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Summary : This book highlights the latest advances in functional micro/nano imaging probes and their applications for biomedical imaging and therapy. Given the rapid emergence of transdisciplinary research and applications in materials, chemical probes and translational medicine in recent years, scientists in these areas are expected to keep up to date on the latest technologies and advances to promote comprehensive innovations. Addressing this need, the book presents recently introduced features, emerging techniques, and new strategies, complemented by detailed illustrations. Covering the status quo and offering an outlook on the future, it benefits all readers with an interest in functional materials, especially micro/nano imaging materials for biomedical imaging applications, providing them with both vital updates and inspiration for their own research.

• Author : Morteza Sasani Ghamsari
• Publisher :Unknown
• Release Date :2018-06-20
• Total pages :114
• ISBN : 9781789232943

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Summary : Nano-bioimaging is a real-time observation method for the study of biological processes in subcellular structures and entire cells. This technique aims to interfere as little as possible with life processes using nanoscale materials and probes. In this method, nanoscale photon source is often used for imaging, and 3D structure of the observed specimen is studied in detail without physical interference. Over the last decade, further boost in bioimaging has led to increase the nano-bioimaging impact that includes many improvements in the data analysis method, image processing, and molecular imaging technology. However, to increase the usage of nano-bioimaging, several developments in the field of diagnosis accuracy, photobleaching prevention, and controlling of the fluorescence resonance energy transfer (FRET) must be achieved. The purpose of this book is to provide a perspective on the current status of nano-bioimaging technologies.

• Author : Chau Lai-Kwan,Huan-Tsung Chang
• Publisher :Unknown
• Release Date :2012-10-26
• Total pages :322
• ISBN : 9789814267243

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Summary : This book provides a comprehensive overview of the use of noble metal nanoparticles for bioimaging and biosensing. It starts with a review on the synthesis, characterization, optical properties, and bioconjugation of noble metal nanoparticles, followed by introduction of various biodetection techniques based on noble metal nanoparticles. In between these topics, microfabrication of biosensing chips and the use of microfluidics to enhance biosensing performance are discussed.

• Author : Sheng Wang
• Publisher :Unknown
• Release Date :2009
• Total pages :246
• ISBN : UCAL:C3528071

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Summary :

• Author : Pandit B. Vidyasagar,Sagar S. Jagtap,Omprakash Yemul
• Publisher :Unknown
• Release Date :2017-05-08
• Total pages :218
• ISBN : 9781351797429

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Summary : This book focuses on the conventional and emerging applications of radiations, which include radio waves and ultraviolet and gamma radiations. It discusses new techniques in radiation therapy and the effects of ionizing radiations on biological systems. The applications of radiations in the synthesis and use of nanoparticles along with the effects of hypergravity indicate a new trend. The book offers a concise account of the latest studies carried out so far and shows the new initiatives to be undertaken in the field of medicine and biology. It covers the medical use of radiations, such as ferrous sulfate–benzoic acid–xylenol orange dosimetry, Co-60 tomotherapy, radio-electro-chemotherapy, and fractional radiotherapy, and radiobiological effects, such as the effects of cell phone radiations on human health parameters and the combined effects of radiations and hypergravity on plants.

• Author : Stefan Haacke,Irene Burghardt
• Publisher :Unknown
• Release Date :2017-01-06
• Total pages :528
• ISBN : 9781315340920

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Summary : Ultrafast Dynamics at the Nanoscale provides a combined experimental and theoretical insight into the molecular-level investigation of light-induced quantum processes in biological systems and nanostructured (bio)assemblies. Topics include DNA photostability and repair, photoactive proteins, biological and artificial light-harvesting systems, plasmonic nanostructures, and organic photovoltaic materials, whose common denominator is the key importance of ultrafast quantum effects at the border between the molecular scale and the nanoscale. The functionality and control of these systems have been under intense investigation in recent years in view of developing a detailed understanding of ultrafast nanoscale energy and charge transfer, as well as fostering novel technologies based on sustainable energy resources. Both experiment and theory have made big strides toward meeting the challenge of these truly complex systems. This book, thus, introduces the reader to cutting-edge developments in ultrafast nonlinear optical spectroscopies and the quantum dynamical simulation of the observed dynamics, including direct simulations of two-dimensional optical experiments. Taken together, these techniques attempt to elucidate whether the quantum coherent nature of ultrafast events enhances the efficiency of the relevant processes and where the quantum–classical boundary sets in, in these high-dimensional biological and material systems. The chapters contain well-illustrated accounts of the authors’ research work, including didactic introductory material, and address a multidisciplinary audience from chemistry, physics, biology, and materials sciences. The book is, therefore, a must-have for graduate- and postgraduate-level researchers who wish to learn about molecular nanoscience from a combined spectroscopic and theoretical viewpoint.

• Author : Tuan Vo-Dinh
• Publisher :Unknown
• Release Date :2007-01-24
• Total pages :792
• ISBN : 1420004441

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Summary : The combination of biology and nanotechnology has led to a new generation of nanodevices that make it possible to characterize the chemical, mechanical, and other molecular properties, as well as discover novel phenomena and biological processes occurring at the molecular level. These advances provide science with a wide range of tools for biomedical applications in therapeutic, diagnostic, and preventive medicine. Nanotechnology in Biology and Medicine: Methods, Devices, and Applications integrates interdisciplinary research and recent advances in instrumentation and methods for applying nanotechnology to various areas in biology and medicine. Pioneers in the field describe the design and use of nanobiosensors with various analytical techniques for the detection and monitoring of specific biomolecules, including cancer cells. The text focuses on the design of novel bio-inspired materials, particularly for tissue engineering applications. Each chapter provides introductory material including a description of methods, protocols, instrumentation, and applications, as well as a collection of published data with an extensive list of references. An authoritative reference written for a broad audience, Nanotechnology in Biology and Medicine: Methods, Devices, and Applications provides a comprehensive forum that integrates interdisciplinary research to present the most recent advances in protocols, methods, instrumentation, and applications of nanotechnology in biology and medicine.

• Author : Ashutosh Tiwari,Anthony P. F. Turner
• Publisher :Unknown
• Release Date :2014-06-26
• Total pages :552
• ISBN : 9781118773819

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Summary : This book provides detailed reviews of a range of nanostructures used in the construction of biosensors as well as the applications of these biosensor nanotechnologies in the biological, chemical, and environmental monitoring fields Biological sensing is a fundamental tool for understanding living systems, but also finds practical application in medicine, drug discovery, process control, food safety, environmental monitoring, defense, and personal security. Moreover, a deeper understanding of the bio/electronic interface leads us towards new horizons in areas such as bionics, power generation, and computing. Advances in telecommunications, expert systems, and distributed diagnostics prompt us to question the current ways we deliver healthcare, while robust industrial sensors enable new paradigms in R&D and production. Despite these advances, there is a glaring absence of suitably robust and convenient sensors for body chemistries. This book examines some of the emerging technologies that are fueling scientific discovery and underpinning new products to enhance the length and quality of our lives. The 14 chapters written by leading experts cover such topics as: ZnO and graphene microelectrode applications in biosensing Assembly of polymers/metal nanoparticles Gold nanoparticle-based electrochemical biosensors Impedimetric DNA sensing employing nanomaterials Graphene and carbon nanotube-based biosensors Computational nanochemistry study of the BFPF green fluorescent protein chromophore Biosynthesis of metal nanoparticles Bioconjugated-nanoporous gold films in electrochemical biosensors The combination of molecular imprinting and nanotechnology Principles and properties of multiferroics and ceramics

• Author : Vladimir N. Uversky
• Publisher :Unknown
• Release Date :2014-08-05
• Total pages :61
• ISBN : 9783319089218

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Summary : In this brief, Vladimir Uversky discusses the paradigm-shifting phenomenon of intrinsically disordered proteins (IDPs) and hybrid proteins containing ordered domains and functional IDP regions (IDPRs). Beginning with an introduction to the concept of protein intrinsic disorder, Uversky then goes on to describe the peculiar amino acid sequences of IDPs, their structural heterogeneity, typical functions and disorder-based binding modes. In the final sections, Uversky discusses IDPs in human diseases and as potential drug targets. This volume provides a snapshot to researchers entering the field as well as providing a current overview for more experienced scientists in related areas.

• Author : Yuri L. Lyubchenko
• Publisher :Unknown
• Release Date :2018-06-29
• Total pages :600
• ISBN : 1493985906

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Summary : This volume presents readers with the latest techniques to study nanoimaging and nanoprobing in application to a broad range of biological systems. The chapters in this book are divided into five parts, and cover topics such as imaging and probing of biomacromolecules including high-speed imaging and probing with AFM; probing chromatin structure with magnetic tweezers; and fluorescence correlation spectroscopy on genomic DNA in living cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and through, Nanoscale Imaging: Methods and Protocols is a valuable resource for anyone interested in learning more about this developing and expanding field.

• Author : Hiroshi Masuhara,Satoshi Kawata
• Publisher :Unknown
• Release Date :2006-02-06
• Total pages :334
• ISBN : 0080458254

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Summary : This second volume in the Handai Nanophotonics book series covers the area of Nanoplasmonics, a recent hot topic in the field of nanophotonics, impacting a diverse range of research disciplines from information technology and nanotechnology to the bio- and medical sciences. The interaction between photons and metal nanostructures leads to interesting and extraordinary scientific phenomena and produces new functions for nano materials and devices. Newly discovered physical phenomena include local mode of surface plasmon polariton excited in nanoparticles, hot spots on nano-rods and nano-cones, long range mode of surface plasmons excited on thin metal films, and dispersion relationship bandgaps of surface plasmons in periodic metal structures. These have been applied to, for example, single molecule detection and nano-imaging/spectroscopy, photon accumulation for lasing applications, optical nano-waveguides and nano-circuits. * interdisciplinary research text on the application of nanoplasmonics research and effects in devices for applications * bridges the gap between conventional photophysics & photochemistry and nanoscience * continuing the series that focuses on 'hot' areas of photochemistry, optics, material science and bioscience.

• Author : Tuan Vo-Dinh
• Publisher :Unknown
• Release Date :2017-10-03
• Total pages :740
• ISBN : 9781439893791

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Summary : The second edition of Nanotechnology in Biology and Medicine is intended to serve as an authoritative reference source for a broad audience involved in the research, teaching, learning, and practice of nanotechnology in life sciences. This technology, which is on the scale of molecules, has enabled the development of devices smaller and more efficient than anything currently available. To understand complex biological nanosystems at the cellular level, we urgently need to develop a next-generation nanotechnology tool kit. It is believed that the new advances in genetic engineering, genomics, proteomics, medicine, and biotechnology will depend on our mastering of nanotechnology in the coming decades. The integration of nanotechnology, material sciences, molecular biology, and medicine opens the possibility of detecting and manipulating atoms and molecules using nanodevices, which have the potential for a wide variety of biological research topics and medical uses at the cellular level. This book presents the most recent scientific and technological advances of nanotechnology for use in biology and medicine. Each chapter provides introductory material with an overview of the topic of interest; a description of methods, protocols, instrumentation, and applications; and a collection of published data with an extensive list of references for further details. The goal of this book is to provide a comprehensive overview of the most recent advances in instrumentation, methods, and applications in areas of nanobiotechnology, integrating interdisciplinary research and development of interest to scientists, engineers, manufacturers, teachers, and students.

• Author : Mehmet Sengun Ozsoz
• Publisher :Unknown
• Release Date :2012-04-23
• Total pages :400
• ISBN : 9789814241779

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Summary : This book focuses on the basic electrochemical applications of DNA in various areas, from basic principles to the most recent discoveries. The book comprises theoretical and experimental analysis of various properties of nucleic acids, research methods, and some promising applications. The topics discussed in the book include electrochemical detection of DNA hybridization based on latex/gold nanoparticle and nanotubes; nanomaterial-based electrochemical DNA detection; electrochemical detection of microorganism-based DNA biosensors; gold nanoparticle-based electrochemical DNA biosensors; electrochemical detection of the aptamer-target interaction; nanoparticle-induced catalysis for DNA biosensing; basic terms regarding electrochemical DNA (nucleic acids) biosensors; screen-printed electrodes for electrochemical DNA detection; application of field-effect transistors to label free electrical DNA biosensor arrays; and electrochemical detection of nucleic acids using branched DNA amplifiers.

• Author : Khan Maaz
• Publisher :Unknown
• Release Date :2018-07
• Total pages :288
• ISBN : 9781789234787

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Summary :

• Author : Sakthi Kumar,Srivani Veeranarayanan,Aswathy Ravindran Girija
• Publisher :Unknown
• Release Date :2019-03-31
• Total pages :600
• ISBN : 9814800309

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Summary : Cancer research world is positively looking to bio-nanotechnology to find best solutions for a complete cure from cancer, which is not possible with current established treatment methods and nowadays lot of research work is going on in this field. However, during the past more than one decades of our research in the "Nano imaging and drug delivery" field against cancer, though the authors came across many interesting papers and reviews, the authors couldn't see a highly useful book, which can provide very concise but still discussing all fields that related to nano cancer research in diagnosis and Drug delivery. To fill this vacuum, the authors bring forward the book "Bio Nanotechnology in Cancer: Diagnosis and Therapy." This book has been mainly divided into two parts primarily to accommodate the latest bio-nano research in the cancer related field; namely, Nanodiagnostics and Nanotherapeutics and having 12 Chapters in total. This book starts with an Introduction chapter to provide the back ground of Cancer and Cancer therapy.

• Author : Alioscka A. Sousa,Michael J. Kruhlak
• Publisher :Unknown
• Release Date :2012-10-21
• Total pages :510
• ISBN : 1627031367

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Summary : For more than a century, microscopy has been a centerpiece of extraordinary discoveries in biology. Along the way, remarkable imaging tools have been developed allowing scientists to dissect the complexity of cellular processes at the nano length molecular scales. Nanoimaging: Methods and Protocols presents a diverse collection of microscopy techniques and methodologies that provides guidance to successfully image cellular molecular complexes at nanometer spatial resolution. The book's four parts cover: (1) light microscopy techniques with a special emphasis on methods that go beyond the classic diffraction-limited imaging; (2) electron microscopy techniques for high-resolution imaging of molecules, cells and tissues, in both two and three dimensions; (3) scanning probe microscopy techniques for imaging and probing macromolecular complexes and membrane surface topography; and (4) complementary techniques on correlative microscopy, soft x-ray tomography and secondary ion mass spectrometry imaging. Written in the successful format of the Methods in Molecular BiologyTM series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Nanoimaging: Methods and Protocols highlights many of the most exciting possibilities in microscopy for the investigation of biological structures at the nano length molecular scales.

• Author : Anonim
• Publisher :Unknown
• Release Date :2006
• Total pages :229
• ISBN : UCSD:31822036009785

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Summary :

• Author : Aleš Iglič,Damjana Drobne,Veronika Kralj-Iglič
• Publisher :Unknown
• Release Date :2015-06-17
• Total pages :534
• ISBN : 9789814303439

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Summary : This book is a survey on the theoretical as well as experimental results on nanostructures in biological systems. It shows how a unifying approach starting from single-particle energy, deriving free energy of the system and determining the equilibrium by minimizing the free energy, can be applied to describe electrical and elastic phenomena. It helps the readers to use this basic, transparent, and simple approach to develop additional new systems and interactions and describes the theoretical and experimental aspects together so that they support each other in broadening the knowledge on biological systems. It suggests potential use of this knowledge in clinically relevant phenomena such as hemostasis, inflammation, and spreading of cancer and describes some applications in nanotoxicology, such as the interactions between biological membranes and inorganic nanostructures.