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Bioenergetics

Bioenergetics
  • Author : David G. Nicholls
  • Publisher :Unknown
  • Release Date :2013-05-20
  • Total pages :434
  • ISBN : 9780123884312
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Summary : Extensively revised, the fourth edition of this highly successful book takes into account the many newly determined protein structures that provide molecular insight into chemiosmotic energy transduction, as well as reviewing the explosive advances in 'mitochondrial physiology'-the role of the mitochondria in the life and death of the cell. Covering mitochondria, bacteria and chloroplasts, the fourth edition of Bioenergetics provides a clear and comprehensive account of the chemiosmotic theory and its many applications. The figures have been carefully designed to be memorable and to convey the key functional and mechanistic information. Written for students and researchers alike, Bioenergetics is the most well-known, current and respected text on chemiosmotic theory and membrane bioenergetics available. BMA Medical Book Awards 2014-Highly Commended, Basic and Clinical Sciences,2014,British Medical Association Chapters are now divided between three interlocking sections: basic principles, structures and mechanisms, and mitochondrial physiology. Covers new advances in the structure and mechanism of key bioenergetic proteins, including complex I of the respiratory chain and transport proteins. Details cellular bioenergetics, mitochondrial cell biology and signal transduction, and the roles of mitochondria in physiology, disease and aging. Offers readers clear, visual representation of structural concepts through full colour figures throughout the book.

Bioenergetics 2

Bioenergetics 2
  • Author : David G. Nicholls,Stuart J. Ferguson
  • Publisher :Unknown
  • Release Date :2014-06-28
  • Total pages :272
  • ISBN : 9781483214207
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Summary : Bioenergetics 2 aims to clarify topics such as the thermodynamics of bioenergetic processes and the stoichiometries of energy coupling reactions. The book discusses chemiosmotic energy transduction; ion transport across energy-conserving membranes; and quantitative bioenergenetics as the measurement of driving forces. The text also describes the chemiosmotic proton circuit; the respiratory chain; the photosynthetic generators of protonmotive force; and the ATP synthase. The secondary transport of products across the membrane, as well as the structures of the bacterial photosynthetic reaction center and bacteriorhodopsin are also considered. Biochemists will find the book invaluable.

Clinical Bioenergetics

Clinical Bioenergetics
  • Author : Sergej M. Ostojic
  • Publisher :Unknown
  • Release Date :2020-11-12
  • Total pages :716
  • ISBN : 9780128227725
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Summary : Clinical Bioenergetics: From Pathophysiology to Clinical Translation provides recent developments surrounding the etiology and pathophysiology of inherited and acquired energy-delated disorders. Across 40 chapters, world leaders in bioenergetics and mitochondrial medicine discuss novel methodologies designed to identify deficiencies in cellular bioenergetics, as well as the safety and efficacy of emerging management strategies to address poor cellular bioenergetics. Topics discussed include the omics landscape of impaired mitochondrial bioenergetics, hormones, tissue bioenergetics and metabolism in humans. Disease-specific case studies, modes of analysis in clinical bioenergetics, and therapeutic opportunities for impaired bioenergetics, addressing both known treatment pathways and future directions for research, are discussed in-depth. Diseases and Disorders examined include brain injury, chronic fatigue syndrome, psychiatric disorders, pulmonary fibrosis, neurodegenerative disorders, heart failure, chronic kidney disease, obesity, and insulin resistance, among others. Provides a thorough discussion of foundational aspects of bioenergetics and disease, modes of analysis, and treatments for impaired bioenergetics Discusses the role of bioenergetics and treatment pathways in brain injury, chronic fatigue syndrome, psychiatric disorders, pulmonary fibrosis, neurodegenerative disorders, heart failure, chronic kidney disease, obesity, and insulin resistance, among other diseases and disorders Features chapter contributions from international leaders in translational bioenergetics research and clinical practice

Bioenergetics

Bioenergetics
  • Author : Chong H. Kim,Takayuki Ozawa
  • Publisher :Unknown
  • Release Date :2012-12-06
  • Total pages :484
  • ISBN : 9781468458350
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Summary : The emergence of the Biochemical Sciences is underlined by the FAOB symposium in Seoul and highlighted by this Satellite meeting on the "New Bioenergetics. " Classical mitochondrial electron transfer and energy coupling is now complemented by the emerging molecular biology of the respiratory chain which is studied hand in hand with the recognition of mitochondrial disease as a major and emerging study in the basic and clinical medical sciences. Thus, this symposium has achieved an important balance of the fundamental and applied aspects of bioenergetics in the modern setting of molecular biology and mitochondrial disease. At the same time, the symposium takes note not only of the emerging excellence of Biochemical Studies in the Orient and indeed in Korea itself, but also retrospectively enjoys the history of electron transport and energy conservation as represented by the triumvirate ofYagi, King and Slater. Many thanks are due Drs. Kim and Ozawa for their elegant organization of this meeting and its juxtaposition to the FAOB Congress. Britton Chance April 2, 1990 v PREFACE This book contains the contributed papers presented at the "International Symposium on Bioenergetics: Molecular Biology, Biochemistry and Pathology", held in Seoul, Korea, August 18-21, 1989, sponsored by International Union of Biochemistry (as ruB Symposium No. 191) and Ewha Womans University, Seoul, Korea. The symposium was held in honor of Professor Kunio Yagi to commemorate his 70th birthday.

Bioenergetics

Bioenergetics
  • Author : Lars Garby,Poul S. Larsen,Poul Steen Larsen
  • Publisher :Unknown
  • Release Date :1995-02-24
  • Total pages :270
  • ISBN : 0521451434
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Summary : The original authors-see later for detail

Bioenergetics

Bioenergetics
  • Author : David G. Nicholls,Stuart J. Ferguson
  • Publisher :Unknown
  • Release Date :2002-07-03
  • Total pages :288
  • ISBN : 9780080527932
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Summary : This new edition of Bioenergetics presents a clear and up-to-date explanation of the chemiosmotic theory and covers mitochondria, bacteria, and chloroplasts. It takes account of the many newly determined structures, such as ATP synthase and the two photosystems of photosynthesis, that provide molecular insight into chemiosmotic energy transduction. This edition includes additional color figures of protein structures and many newly drawn illustrations designed to enable the reader to grasp the fundamental insights that are derived from knowing the structure. Every chapter has been extensively revised and updated and a new chapter on the study of the bioenergetics of mitochondria in the intact cell is included to satisfy the enormous interest in this topic. Written for students and researchers alike, this book is the most current text on the chemiosmotic theory and membrane bioenergetics available. Key Features * Chapter on the study of bioenergetics of mitochondria in the intact cell * Appendix listing protein structure resources * Additional colour plates of protein structures * Many newly drawn illustrations * Website

Thermodynamics in Bioenergetics

Thermodynamics in Bioenergetics
  • Author : Jean-Louis Burgot
  • Publisher :Unknown
  • Release Date :2019-09-10
  • Total pages :344
  • ISBN : 9781351034203
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Summary : Thermodynamics in Bioenergetics aims to supply students with the knowledge and understanding of the critical concepts and theories that are needed in the biochemistry and bioenergetics fields. Biochemical reactions highlighting thermodynamics, chemical kinetics, and enzymes are addressed in the text. Author, Jean-Louis Burgot, guides the reader through the starting points, strategy description, and theory results to facilitate their comprehension of the theories and examples being discussed in the book. Also discussed in the text are the notions of Gibbs energy, entropy, and exergonic and endergonic reactions.

Molecular System Bioenergetics

Molecular System Bioenergetics
  • Author : Valdur Saks
  • Publisher :Unknown
  • Release Date :2008-01-08
  • Total pages :633
  • ISBN : 9783527621101
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Summary : In this first integrated view, practically each of the world's leading experts has contributed to this one and only authoritative resource on the topic. Bringing systems biology to cellular energetics, they address in detail such novel concepts as metabolite channeling and medical aspects of metabolic syndrome and cancer.

Bioenergetics

Bioenergetics
  • Author : Günter Schäfer,Harvey Penefsky
  • Publisher :Unknown
  • Release Date :2008-05-24
  • Total pages :312
  • ISBN : 9783540786221
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Summary : The fermentation of sugar by cell-free yeast extracts was demonstrated more than a century ago by E. Buchner (Nobel Prize 1907). Buchner’s observations put an end to previous animistic theories regarding cellular life. It became clear that metabolism and all cellular functions should be accessible to explication in chemical terms. Equally important for an understanding of living systems was the concept, explained in physical terms, that all living things could be cons- ered as energy converters [E. Schrödinger (Nobel Prize 1933)] which generate complexity at the expense of an increase in entropy in their environment. Bioenergetics was established as an essential branch of the biochemical sciences by the investigations into the chemistry of photosynthesis in i- lated plant organelles [O. Warburg (Nobel Prize 1931)] and by the discovery that mitochondria were the morphological equivalent that catalyzed cellular respiration. The ?eld of bioenergetics also encompasses a large variety of ad- tional processes such as the molecular mechanisms of muscle contraction, the structure and driving mechanisms of microbial ?agellar motors, the energetics of solute transport, the extrusion of macromolecules across membranes, the transformation of quanta of light into visual information and the maintenance of complex synaptic communications. There are many other examples which, in most cases, may perform secondary energy transformations, utilizing - ergy stored either in the cellular ATP pool or in electrochemical membrane potentials.

Principles of Bioenergetics

Principles of Bioenergetics
  • Author : Vladimir P. Skulachev,Alexander V. Bogachev,Felix O. Kasparinsky
  • Publisher :Unknown
  • Release Date :2012-12-15
  • Total pages :436
  • ISBN : 9783642334306
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Summary : Principles of Bioenergetics summarizes one of the quickly growing branches of modern biochemistry. Bioenergetics concerns energy transductions occurring in living systems and this book pays special attention to molecular mechanisms of these processes. The main subject of the book is the "energy coupling membrane" which refers to inner membranes of intracellular organelles, for example, mitochondria and chloroplasts. Cellular cytoplasmic membranes where respiratory and photosynthetic energy transducers, as well as ion-transporting ATP-synthases (ATPases) are also part of this membrane. Significant attention is paid to the alternative function of mitochondria as generators of reactive oxygen species (ROS) that mediate programmed death of cells (apoptosis and necrosis) and organisms (phenoptosis). The latter process is considered as a key mechanism of aging which may be suppressed by mitochondria-targeted antioxidants.

Foundations of Bioenergetics

Foundations of Bioenergetics
  • Author : Harold Morowitz
  • Publisher :Unknown
  • Release Date :2012-12-02
  • Total pages :364
  • ISBN : 9780323154055
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Summary : Foundations of Bioenergetics provides an introduction to the physical foundations of bioenergetics and the methods of applying these constructs to biological problems. It combines parts of thermal physics, biochemistry, ecology, and cellular and organismic biology into a single coherent work. Much of the material in this volume comes from ""Entropy for Biologists,"" an introductory thermodynamics book aimed particularly at life scientists. Some of the topics originally appeared in the monograph ""Energy Flow in Biology."" The current volume expands on that material with respect to biological applications and attempts to bridge the gap between physics and biology. The book explains basic concepts such as energy, temperature, the second law of thermodynamics, entropy, information theory, and statistical mechanics. It discusses the relations between thermodynamics and statistical mechanics, free-energy functions, radiant energy, the free energy of cells and tissue, chemical kinetics, and cyclic flows. It examines the relationships between energy flows and biological processes; applications of the concepts of Gibbs free energy, chemical potential, and activity; and measurements of temperature, energy, and thermochemical quantities. The book also includes chapters that deal with irreversible dynamics, irreversible theory, and osmotic flow.

Mechanisms in Bioenergetics

Mechanisms in Bioenergetics
  • Author : Efraim Racker
  • Publisher :Unknown
  • Release Date :2014-05-10
  • Total pages :272
  • ISBN : 9781483268934
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Summary : Advanced Biochemistry: Mechanisms in Bioenergetics provides information pertinent to the fundamental aspects of the mechanisms in bioenergetics. This book covers a variety of topics, including the enzymatic mechanism of ATP formation and the regulatory mechanisms that control its metabolic utilization. Organized into three parts encompassing 18 lectures, this book begins with an overview of the process of converting nutrients into forms of useful energy, which is the essence of energy metabolism. This text then explores the properties that have a specific bearing on the problem of oxidative phosphorylation. Other lectures consider the phosphoroclastic reaction with pyruvate, which plays a curious and apparently specific role in nitrogen fixation. This book discusses as well the operation of control mechanisms of energy metabolism in intact cells. The final lecture analyzes the rate-limiting steps in carbohydrate metabolism of various cells and some of the metabolic factors that govern them. This book is a valuable resource for graduate students.

The Charnoly Body

The Charnoly Body
  • Author : Sushil Sharma
  • Publisher :Unknown
  • Release Date :2019-01-31
  • Total pages :388
  • ISBN : 9781351366700
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Summary : Diversified physicochemical injuries trigger Charnoly body (CB) formation as pleomorphic, electron-dense, multi-lamellar stacks of nonfunctional mitochondrial membranes in the most vulnerable cell. Free radicals induce downregulation of mitochondrial DNA, microRNA, AgNOR, and epigenetics to trigger CB molecular pathogenesis. CB is eliminated by energy (ATP)-driven lysosome-dependent charnolophagy as a basic molecular mechanism of intracellular detoxification to prevent acute and chronic diseases. Accumulation of CB at the junction of axon hillock and charnolosome (CS) at the synapses causes cognitive impairments; whereas, nonspecific induction of CB causes GIT stress, myelosuppression, alopecia, neurotoxicity, cardiotoxicity, and infertility in multidrug-resistant malignancies. Hence, stem cell-specific CB, charnolophagy, and CS agonists/antagonists are introduced as novel charnolopharmacotherapeutics for the successful treatment of cardiovascular diseases, neurodegenerative diseases, infectious diseases, drug addiction, and cancer. Nanoparticles to improve drug delivery, CS exocytosis, and disease-specific spatiotemporal charnolosomics employing correlative and combinatorial bioinformatics boost mitochondrial bioenergetics through balanced diet, exercise, and antioxidants. The book will be of interest to medical scientists and practitioners.

Molecular Mechanisms in Bioenergetics

Molecular Mechanisms in Bioenergetics
  • Author : L. Ernster
  • Publisher :Unknown
  • Release Date :1992-12-16
  • Total pages :520
  • ISBN : 0080860834
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Summary : This book summarises current knowledge of the structure, function,biosynthesis and regulation of energy-transducing enzymes inmitochondria, chloroplasts and bacteria. Each of the twenty chapters is written by top experts in their field, and Prof. Ernster has ensured that the book as a whole gives a well-integrated picture of the present state of knowledge of the field at its different levels and complexities. Since the publication of Bioenergetics edited by Lars Ernster in 1984, (New Comprehensive Biochemistry Vol. 9) the whole field of bioenergetics has undergone a tremendous expansion. Additionally a transition from membrane bioenergetics to molecular bioenergetics has accompanied this expansion - due mainly to the spectacular progress in the field of molecular biology over the past twenty years. Hence this volume, Molecular Mechanisms in Bioenergetics, is certain to be of interest, not only to the specialist in bioenergetics, but also to researchers working in the various fields of biophysics, biochemistry, molecular biology, genetics, cell biology and physiology. Also of interest, this volume contains an historical introduction, including a list of earlier publications relating to the history of bioenergetics.

Bioenergetics

Bioenergetics
  • Author : Albert L. Lehninger
  • Publisher :Unknown
  • Release Date :1971
  • Total pages :245
  • ISBN : OCLC:462816512
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Bioenergetics at a Glance

Bioenergetics at a Glance
  • Author : D. A. Harris
  • Publisher :Unknown
  • Release Date :2009-06-29
  • Total pages :120
  • ISBN : 9781444313772
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Summary : Bioenergetics is the study of the way biological systems, usuallyat the molecular level, utilize and convert energy in order todrive the biochemical reactions that constitute life. However,because of its often quantitative basis and the amount of technicaljargon, the subject tends to alienate and intimidate students. Thisbeautifully illustrated text has a lucid and logical approach tothe subject. The text uses the modern perspective throughout sothat the student is given an easily assimilable, logicalintroduction to the important concepts of the subject, particularythe core concept, the 'chemiosmotic theory'. It has beenspecifically designed to make information easily accessible bydevoting each double-page spread to one topic. Within the spread, avariety of carefully constructed diagrams present information in aconcise and innovative manner. The text is further enhanced by acomprehensive guide to additional reading. Original, easily understood combination of visual and writteninformation. 43 double-page speads give a clear and concise introduction tothis traditionally difficult subject. The most up to date text available, covering all modernmolecular genetic techniques. Competitively priced.

Membrane Bioenergetics

Membrane Bioenergetics
  • Author : Vladimir P. Skulachev
  • Publisher :Unknown
  • Release Date :2013-11-11
  • Total pages :442
  • ISBN : 9783642729782
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Summary : Membrane bioenergetics is one of the most rapidly growing areas within physico-chemical biology. Main aspects treated in this book include energy conservation and utilization by membrane-linked molecular mechanisms such as intracellular respiration, photosynthesis, transport phenomena, rotation of bacterial flagella, and the regulation of heat production.

Bioenergetics of the Cell: Quantitative Aspects

Bioenergetics of the Cell: Quantitative Aspects
  • Author : Valdur A. Saks,Renée Ventura-Clapier,Xavier Leverve,André Rossi,Michel Rigoulet
  • Publisher :Unknown
  • Release Date :2012-12-06
  • Total pages :460
  • ISBN : 9781461556534
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Summary : This volume continues the discussion of the problems of in vivo and in vitro. The recently solved X-ray structure of the mitochondrial creatine kinase and its molecular biology cellular bioenergetics - the tradition we started in 1994 by publication of the focused issue of Molecular and Cellular are analyzed with respect to its molecular physiology and Biochemistry, volume 133/134 and a book 'Cellular Bio functional coupling to the adenine nucleotide translocase, as energetics: role of coupled creatine kinases' edited by V. Saks well as its participation, together with the adenylate kinase and R. Ventura-Clapier and published by Kluwer Publishers, system, in intracellular energy transfer. The results of the Dordrecht -Boston. In the present volume, use of quantitative studies of creatine kinase deficient transgenic mice are methods of studies of organized metabolic systems, such as summarized and analyzed by using mathematical models of mathematical modeling and Metabolic Control Analysis, for the compartmentalized energy transfer, thus combining two investigation of the problems of bioenergetics of the cell is powerful new methods of the research. All these results, described together with presentation of new experimental together with the physiological and NMR data on the cardiac results. The following central problems of the cellular bio metabolic and mitochondrial responses to work-load changes energetics are the focus of the discussions: the mechanisms concord to the concept of metabolic networks of energy of regulation of oxidative phosphorylation in the cells in vivo transfer and feedback regulation.

Environmental Bioenergetics

Environmental Bioenergetics
  • Author : Anke Marianne Herrmann,Doug LaRowe,Alain F. Plante
  • Publisher :Unknown
  • Release Date :2020-01-10
  • Total pages :229
  • ISBN : 9782889633081
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Summary :

Bioenergetic Processes of Cyanobacteria

Bioenergetic Processes of Cyanobacteria
  • Author : Guenter A. Peschek,Christian Obinger,Gernot Renger
  • Publisher :Unknown
  • Release Date :2011-05-26
  • Total pages :720
  • ISBN : 9789400703889
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Summary : This publication is unique among a number of books on cyanobacteria because it focuses on the bioenergetics of these widespread organisms which are the evolutionary prerequisite for the development of all higher forms of life on our "blue" planet. The book primarily addresses questions of energy conversion by the fundamental bioenergetic processes: (oxygenic) photosynthesis, (aerobic) respiration, and (anaerobic) fermentation which uniquely occur together in these prokaryotic cells. Thermophilic cyanobacteria offer the most suitable material for high resolution structure analyses of Photosystem I and II and other electron transport complexes by X-ray crystallography (for example, at present the structure of Photosystem II at atomic resolution is only known for these organisms). These achievements during the last decade represent a milestone in our understanding of the complexes which are crucial for solar energy exploitation through photosynthetic water splitting. The present work represents an ambitious attempt to achieve the goal of a synoptic state-of-the-art picture by casting together the mosaics of detailed knowledge described by leading experts in the field. It contains 24 chapters written by 35 authors from Europe, USA, India and Japan. The book is aimed at reaching a broad audience ranging from students to experienced scientists. The editors wish all readers a pleasant and stimulating journey through the fascinating “world” of the bioenergetics of cyanobacteria and sincerely hope that this book will not only be of great value for the experts but also entice young people into this exciting research area with the aim to address successfully the challenging problems of high relevance that are still waiting for a satisfactory answer.

Bioenergetics Of Wild Herbivores

Bioenergetics Of Wild Herbivores
  • Author : Robert J. Hudson
  • Publisher :Unknown
  • Release Date :2018-01-18
  • Total pages :324
  • ISBN : 9781351087117
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Summary : Bioenergetics is an emerging discipline which offers a more profound understanding of the ecology, behaviour, and evolution of wild herbivores. Increasingly, bioenergetic principles have been applied in management since they provide insight into population dynamics and are relevant to manipulation of habitats and assessment of the impacts of resource development. Growing interest in the agricultural potential of wild herbivores has provided further impetus. In spite of this promise, there are few comprehensive syntheses of the concept and its application to wild herbivores. This volume attempts to fill this need. This book provides a great amount of detail but its expressive aim is to lead us to the whole animal, to a herd, to population as integral parts of an ecological entity which in turn is the result of evolutionary forces.The concept of this book promises the realization of an overdue change in the approach to bioenergetics, to nutrition and husbandry, and thus to the management of wild herbivores: the final emancipation from rules and views based primarily on domesticated herbivores or on experimental animals held under unnatural conditions, necessarily impending them behaviourally, physically, and psychically.