Download Biometals In Autism Spectrum Disorders Book PDF

Download full Biometals In Autism Spectrum Disorders books PDF, EPUB, Tuebl, Textbook, Mobi or read online Biometals In Autism Spectrum Disorders anytime and anywhere on any device. Get free access to the library by create an account, fast download and ads free. We cannot guarantee that every book is in the library.

Biometals in Autism Spectrum Disorders

Biometals in Autism Spectrum Disorders
  • Author : Andreas Grabrucker
  • Publisher :Unknown
  • Release Date :2020-07-08
  • Total pages :222
  • ISBN : 9780128211335
GET BOOK HERE

Summary : Biometals in Autism Spectrum Disorders will be the first to focus on trace metals and autism. Compared to other references examining ASDs or metallomics, a focused presentation of the findings of abnormal metal homeostasis in ASD has not yet come to be. This book provides for readers an overview of current findings on trace metal biology with respect to its role in ASD etiology and discusses how abnormal trace metal biology may be a common factor of several genetic and non-genetic causes of ASDs considered unrelated in the past. This will open new vistas for the development of new therapies based on targeted manipulation of trace metal homeostasis and generate awareness that trace metal levels during pregnancy must be tightly monitored. Reviews the role of trace metals in brain development Summarizes research linking trace metals and autism Explores heterogenous phenotypes as a factor of genetic and non-genetic factors Includes animal and human stem research Contains many diagrams, tables, and flow charts Proposes future therapies based on biometal homeostasis

Biometals in Neurodegenerative Diseases

Biometals in Neurodegenerative Diseases
  • Author : Anthony R. White,Michael Aschner,Lucio G. Costa,Ashley I. Bush
  • Publisher :Unknown
  • Release Date :2017-04-28
  • Total pages :462
  • ISBN : 9780128045633
GET BOOK HERE

Summary : Biometals in Neurodegenerative Diseases: Mechanisms and Therapeutics is an authoritative and timely resource bringing together the major findings in the field for ease of access to those working in the field or with an interest in metals and their role in brain function, disease, and as therapeutic targets. Chapters cover metals in Alzheimer’s Disease, Parkinson’s Disease, Motor Neuron Disease, Autism and lysosomal storage disorders. This book is written for academic researchers, clinicians and advanced graduate students studying or treating patients in neurodegeneration, neurochemistry, neurology and neurotoxicology. The scientific literature in this field is advancing rapidly, with approximately 300 publications per year adding to our knowledge of how biometals contribute to neurodegenerative diseases. Despite this rapid increase in our understanding of biometals in brain disease, the fields of biomedicine and neuroscience have often overlooked this information. The need to bring the research on biometals in neurodegeneration to the forefront of biomedical research is essential in order to understand neurodegenerative disease processes and develop effective therapeutics. Authoritative and timely resource bringing together the major findings in the field for those with an interest in metals and their role in the brain function, disease, and as therapeutic targets Written for academic researchers, clinicians and advanced graduate students studying, or treating, patients in neurodegeneration, neurochemistry, neurology and neurotoxicology Edited by international leaders in the field who have contributed greatly to the study of metals in neurodegenerative diseases

Personalized Food Intervention and Therapy for Autism Spectrum Disorder Management

Personalized Food Intervention and Therapy for Autism Spectrum Disorder Management
  • Author : M. Mohamed Essa,M. Walid Qoronfleh
  • Publisher :Unknown
  • Release Date :2020-01-31
  • Total pages :693
  • ISBN : 9783030304027
GET BOOK HERE

Summary : The book focuses on implications of traditional and processed foods for autism spectrum disorder (ASD) intervention and management. Numerous phytonutrients and pharmacologically active compounds in edible natural products and diet could influence and offer protection to neuronal dysfunction that occurs due to ASD. The neuroprotective effects of various fruits, vegetables, nuts and seeds phytochemicals, and other natural bioactive ingredients against ASD and related conditions are discussed. Topics such as the possible neuroprotective mechanism of action of these foods and the therapeutic role of antioxidants in relation to ASD are addressed. This book also highlights the scope of using anti-inflammatory agents and antioxidants to promote neurogenesis and improve other symptoms in ASD. It emphasizes personalized nutritional approaches with dietary management of neurodevelopmental disorders/ASD cases. Information in this book is relevant to researchers in the field of complementary and alternative medicine, nutraceuticals, neuroscience, agriculture, nutrition, and food science. This volume is beneficial to students of varying levels, and across multiple disciplines.

Shankopathies: Shank Protein Deficiency-Induced Synaptic Diseases

Shankopathies: Shank Protein Deficiency-Induced Synaptic Diseases
  • Author : Elodie Ey,Thomas Bourgeron,Tobias Maria Boeckers,Eunjoon Kim,Kihoon Han
  • Publisher :Unknown
  • Release Date :2020-03-10
  • Total pages :229
  • ISBN : 9782889635672
GET BOOK HERE

Summary :

Nutritional Deficiency

Nutritional Deficiency
  • Author : Pinar Erkekoglu,Belma Kocer-Gumusel
  • Publisher :Unknown
  • Release Date :2016-07-20
  • Total pages :206
  • ISBN : 9789535124375
GET BOOK HERE

Summary : Intake of a sufficient diet will provide an individual to live a healthy and functional life. However, poor intake of different nutritional components, such as proteins, vitamins, minerals, and trace elements, may lead to health problems that can cause morbidity and finally mortality. Assessment of nutritional status involves physical examination, comprehensive evaluation of biochemical tests, body composition, and organ functions. Both high and low intake of nutritional elements may lead to significant health impairment. The main aim of the book Nutritional Deficiency is to determine the relationships between nutritional status and general health. The authors, who are contributing to the book, particularly focused on iron, vitamin D, and zinc deficiencies, which are global health problems. Besides, some chapters mention the impact of different nutritional deficiencies in susceptible periods of life, such as pregnancy and elderly. Besides, as a result of these deficiencies, different health conditions, such as depression, anemia, loss of neuronal plasticity, and cancer, are widely scrutinized in the book. One chapter mainly focuses on the effects of disasters on nutrition and disaster-caused malnutrition in underdeveloped countries. This book will widen the knowledge store of the readers on the effects of nutrition on general health, how nutritional deficiencies arise when there is a health problem, and how the nutritional status affects susceptible populations.

The Therapeutic Use of N-Acetylcysteine (NAC) in Medicine

The Therapeutic Use of N-Acetylcysteine (NAC) in Medicine
  • Author : Richard Eugene Frye,Michael Berk
  • Publisher :Unknown
  • Release Date :2018-09-20
  • Total pages :394
  • ISBN : 9789811053115
GET BOOK HERE

Summary : Focusing on the practical use of N-Acetyl-Cysteine (NAC) in medicine, this book provides a comprehensive review of the basic biological and clinical studies documenting its benefits in treating medical disease. NAC is perhaps best known as an antidote for acetaminophen, but its therapeutic effect in a wide range of medical diseases has recently been realized. In addition to its well recognized use in radiological contrast prophylaxis for renal disease and pulmonary disorders, studies have suggested significant promise in psychiatric and neurological disorders such as addiction, Alzheimer’s disease, ataxia, autism, bipolar disorder, depression, epilepsy, neuropathy, obsessive-compulsive disorder, schizophrenia, traumatic brain injury and trichotillomania in addition to promising studies in audiology, cardiology, exercise physiology, gastroenterology, hematology, infectious disease, infertility and ophthalmology. Given the promising studies for a wide range of medical conditions, coupled with a excellent safety profile, the potential for NAC in the treatment of human disease appears considerable. Dr Leonore A Herzenberg from Stanford University, a pioneer of redox physiology and the use of NAC, provides a succinct history of the development of the therapeutic use of NAC for medical disease. This is followed by a series of basic science chapters outlining the role of NAC in important physiological processes, including modulation of dopamine and glutamate neurotransmitter systems, redox and mitochondrial metabolism, apoptosis and inflammation. The last section of the book is dedicated to clinically oriented chapters that comprehensively review the literature on medical disorders in which NAC has been found to be effective, including toxicity and cardiovascular, gastrointestinal, neurological, psychiatric, pulmonary and renal disorders. Each chapter reviews the theoretical biological mechanisms of NAC for the specific diseases reviewed, rates the clinical studies using a standardized criteria in order to provide an objective level of evidence and grade of recommendation for the use of NAC for specific medical conditions and outlines the ongoing clinical trials examining NAC for the treatment of specific diseases. Final chapters review the clinical evidence verifying that specific theoretical biological mechanisms are actually being targeted by NAC in medical disease. Studies on the pharmacology, formulation and potential adverse effects of NAC are also reviewed. A final chapter synthesizes the clinical studies to suggest that the effectiveness of NAC may signal a new basic physiological disorder, glutathione deficiency, which may be an important pathophysiological mechanism of many diseases.

A Time for Metabolism and Hormones

A Time for Metabolism and Hormones
  • Author : Paolo Sassone-Corsi,Yves Christen
  • Publisher :Unknown
  • Release Date :2016-04-04
  • Total pages :132
  • ISBN : 9783319270692
GET BOOK HERE

Summary : Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspects of how organisms cope with changes in the environment and subsequent control of homeostasis. This field is opening new avenues in our understanding of metabolism and endocrinology. A panel of the most distinguished investigators in the field gathered together to discuss the present state and the future of the field. The editors trust that this volume will be of use to those colleagues who will be picking up the challenge to unravel how the circadian clock can be targeted for the future development of specific pharmacological strategies toward a number of pathologies.

Current Strategies for the Biochemical Diagnosis and Monitoring of Mitochondrial Disease

Current Strategies for the Biochemical Diagnosis and Monitoring of Mitochondrial Disease
  • Author : Iain P. Hargreaves
  • Publisher :Unknown
  • Release Date :2018-10-16
  • Total pages :238
  • ISBN : 9783038972402
GET BOOK HERE

Summary : This book is a printed edition of the Special Issue "Current Strategies for the Biochemical Diagnosis and Monitoring of Mitochondrial Disease" that was published in JCM

Assessment of Autism Spectrum Disorder, Second Edition

Assessment of Autism Spectrum Disorder, Second Edition
  • Author : Sam Goldstein,Sally Ozonoff
  • Publisher :Unknown
  • Release Date :2018-03-08
  • Total pages :494
  • ISBN : 9781462533107
GET BOOK HERE

Summary : This authoritative resource, now thoroughly revised for DSM-5, has set the standard for the comprehensive assessment of autism spectrum disorder (ASD). Leading experts demonstrate how to craft a scientifically grounded profile of each child?s strengths and difficulties, make a formal diagnosis, and use assessment data to guide individualized intervention in clinical and school settings. Chapters review state-of-the-art instruments and approaches for evaluating specific areas of impairment in ASD and co-occurring emotional and behavioral disorders. Considerations in working with children of different ages are highlighted. With a primary focus on children, several chapters also address assessment of adolescents and adults. ÿ New to This Edition *Chapter on key implications of DSM-5 diagnostic criteria, plus related updates throughout the volume. *Chapter on advances in early identification (ages 0?3). *Chapter with in-depth case examples illustrating the evaluation decision-making process and common diagnostic challenges. *Chapters on pseudoscience (including strategies for advising parents) and future directions in the field. *Current assessment data, numerous new and revised measures, and cutting-edge screening approaches.

Neurotoxicity of Metals

Neurotoxicity of Metals
  • Author : Michael Aschner,Lucio G. Costa
  • Publisher :Unknown
  • Release Date :2017-09-09
  • Total pages :383
  • ISBN : 9783319601892
GET BOOK HERE

Summary : Assembles international authorities to address contemporary research in metal neurotoxicity. Essential and non-essential metals play an important role in neurodevelopmental and neurodegenerative diseases. Recent developments in understanding the role of metals in the etiology of these disorders have led to rapid growth in clarifying the pathology of some of the most devastating diseases we face and in identifying potential new therapies. Few books or periodicals have been wholly dedicated to the topic of metals, and this collection is intended to serve as a resource for all researchers interested in metals and their role in health and disease.

Autism

Autism
  • Author : Abha Chauhan,Ved Chauhan,Ted Brown
  • Publisher :Unknown
  • Release Date :2009-10-26
  • Total pages :452
  • ISBN : 1420068873
GET BOOK HERE

Summary : In 2007, the Centers for Disease Control and Prevention issued an autism alarm, estimating that one in 150 children may be affected by autism spectrum disorder. Autism has been treated mainly with technical approaches: principally applied behavior analysis and psychopharmacology. The findings in this book implicate oxidative stress as a common feature in autism, and support the claim that oxidative stress and intracellular redox imbalance can be induced or triggered in autism by exposure to certain environmental agents. Such findings could point the way to new treatment approaches in autism. Autism: Oxidative Stress, Inflammation, and Immune Abnormalities brings together a wealth of cutting-edge evidence that is already influencing how we treat this serious condition. It looks at the role of neuropathological abnormalities, genetics, and those factors common to oxidative stress such as inflammation, immune dysfunction, aberrant cellular signaling, and gene-environment interactions. Among dozens of research topics, this volume — Looks at interactions between genetic and environmental factors such as the maternal immune environment and prenatal/postnatal environmental stressors Summarizes evidence for oxidative damage and inflammation in autism Introduces a PDD behavior inventory as a tool for assessing autism Considers autism as an aberrant adaptive response to neuroinflammation and oxidative stress Examines the role of abnormal calcium signaling and the hypothesis that it may represent a target for novel therapeutics Presents a hypothesis that autism arises from the dysregulation of a unified gut/brain system rather than originating in the brain alone Proposes the utility of using a biopsychosocial method to treat autism This book shows us that autism is not only developmental but also a chronic condition based on active pathophysiology, and that it is not only behavioral but also presents somatic and systemic features. The findings in these chapters support the theory that oxidative stress plays an important role in autism. They also point to the value of conducting in-depth mechanistic studies as a way to uncover new targets for therapeutic intervention in autism.

Calcium Signaling

Calcium Signaling
  • Author : Md. Shahidul Islam
  • Publisher :Unknown
  • Release Date :2019-10-23
  • Total pages :1110
  • ISBN : 9783030124571
GET BOOK HERE

Summary : This volume contains a unique selection of chapters covering a wealth of contemporary topics in this ubiquitous and diverse system of cell signaling. It offers much more than the accessibility and authority of a primary text book, exploring topics ranging from the fundamental aspects of calcium signaling to its varied clinical implications. It presents comprehensive discussion of cutting-edge research alongside detailed analysis of critical issues, at the same time as setting out testable hypotheses that point the way to future scientific endeavors. The contributions feature material on theoretical and methodological topics as well as related subjects including mathematical modeling and simulations. They examine calcium signaling in a host of contexts, from mammalian cells to bacteria, fruit fly and zebrafish. With much of interest to newcomers to the field as well as seasoned experts, this new publication is both wide-ranging and authoritative. The chapter “Calcium Signaling: From Basic to Bedside” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

The Cambridge Handbook of Evolutionary Perspectives on Human Behavior

The Cambridge Handbook of Evolutionary Perspectives on Human Behavior
  • Author : Lance Workman,Will Reader,Jerome H. Barkow
  • Publisher :Unknown
  • Release Date :2020-01-31
  • Total pages :604
  • ISBN : 1316642828
GET BOOK HERE

Summary : The transformative wave of Darwinian insight continues to expand throughout the human sciences. While still centered on evolution-focused fields such as evolutionary psychology, ethology, and human behavioral ecology, this insight has also influenced cognitive science, neuroscience, feminist discourse, sociocultural anthropology, media studies, and clinical psychology. This handbook's goal is to amplify the wave by bringing together world-leading experts to provide a comprehensive and up-to-date overview of evolution-oriented and influenced fields. While evolutionary psychology remains at the core of the collection, it also covers the history, current standing, debates, and future directions of the panoply of fields entering the Darwinian fold. As such, The Cambridge Handbook of Evolutionary Perspectives on Human Behavior is a valuable reference not just for evolutionary psychologists but also for scholars and students from many fields who wish to see how the evolutionary perspective is relevant to their own work.

Scanning Microscopy for Nanotechnology

Scanning Microscopy for Nanotechnology
  • Author : Weilie Zhou,Zhong Lin Wang
  • Publisher :Unknown
  • Release Date :2007-03-09
  • Total pages :522
  • ISBN : 9780387396200
GET BOOK HERE

Summary : This book presents scanning electron microscopy (SEM) fundamentals and applications for nanotechnology. It includes integrated fabrication techniques using the SEM, such as e-beam and FIB, and it covers in-situ nanomanipulation of materials. The book is written by international experts from the top nano-research groups that specialize in nanomaterials characterization. The book will appeal to nanomaterials researchers, and to SEM development specialists.

Drug-induced Nutrient Depletion Handbook

Drug-induced Nutrient Depletion Handbook
  • Author : Ross Pelton
  • Publisher :Unknown
  • Release Date :2001
  • Total pages :591
  • ISBN : UOM:39015056514451
GET BOOK HERE

Summary : This work contains a complete and up-to-date listing of all drugs known to deplete the body of nutritional compounds. Alphabetically organized, 150 drugs that cause nutrient depletion are identified and cross-referenced to more detailed descriptions of the nutrients depleted and their actions. Symptoms of depletion and sources of repletion are also included. The appendices include a quick reference drug-induced nutrient depletion table, along with details on food/drug interactions and herb/nutrient depletions.

Nutrition and Immunity

Nutrition and Immunity
  • Author : Maryam Mahmoudi,Nima Rezaei
  • Publisher :Unknown
  • Release Date :2019-07-30
  • Total pages :515
  • ISBN : 9783030160739
GET BOOK HERE

Summary : This volume provides readers with a systematic assessment of current literature on the link between nutrition and immunity. Chapters cover immunonutrition topics such as child development, cancer, aging, allergic asthma, food intolerance, obesity, and chronic critical illness. It also presents a thorough review of microflora of the gut and the essential role it plays in regulating the balance between immune tolerance and inflammation. Written by experts in the field, Nutrition and Immunity helps readers to further understand the importance of healthy dietary patterns in relation to providing immunity against disorders and offering readily available immunonutritional programming in clinical care. It will be a valuable resource for dietitians, immunologists, endocrinologists and other healthcare professionals.

An Introduction to Biological Membranes

An Introduction to Biological Membranes
  • Author : William Stillwell
  • Publisher :Unknown
  • Release Date :2016-06-30
  • Total pages :590
  • ISBN : 9780444637901
GET BOOK HERE

Summary : Introduction to Biological Membranes: Composition, Structure and Function, Second Edition is a greatly expanded revision of the first edition that integrates many aspects of complex biological membrane functions with their composition and structure. A single membrane is composed of hundreds of proteins and thousands of lipids, all in constant flux. Every aspect of membrane structural studies involves parameters that are very small and fast. Both size and time ranges are so vast that multiple instrumentations must be employed, often simultaneously. As a result, a variety of highly specialized and esoteric biochemical and biophysical methodologies are often utilized. This book addresses the salient features of membranes at the molecular level, offering cohesive, foundational information for advanced undergraduate students, graduate students, biochemists, and membranologists who seek a broad overview of membrane science. Significantly expanded coverage on function, composition, and structure Brings together complex aspects of membrane research in a universally understandable manner Features profiles of membrane pioneers detailing how contemporary studies originated Includes a timeline of important discoveries related to membrane science

Movement Disorder Genetics

Movement Disorder Genetics
  • Author : Susanne A. Schneider,José M. Tomás Brás
  • Publisher :Unknown
  • Release Date :2015-05-13
  • Total pages :530
  • ISBN : 9783319172231
GET BOOK HERE

Summary : This book covers recent developments and possible pitfalls in the diagnosis of genetic movement disorders and related conditions. It is divided into three sections: technical and scientific aspects; clinical aspects with guidance towards work-up; and ethical and legal aspects of genetic testing in a clinical and research setting. The first section includes chapters on genetic analysis and counselling with critical discussion of potential problems when interpreting the results. Clinical chapters summarize genetic forms of movement disorders including parkinsonism, tics and dystonia with algorithms for hands-on daily practice. Related conditions such as RLS, ataxias and dementias are also covered. Finally, chapters on ethical and legal aspects of genetic testing are included. Movement Disorder Genetics is aimed at clinicians and scientists working in the field of movement disorders and related conditions.

Human Microbes - The Power Within

Human Microbes - The Power Within
  • Author : Vasu D. Appanna
  • Publisher :Unknown
  • Release Date :2018-02-05
  • Total pages :175
  • ISBN : 9789811076848
GET BOOK HERE

Summary : This book offers a unique perspective on the invisible organ, a body part that has been visualized only recently. It guides the readers into the world of the microbial constituents that make humans the way they are. The vitamins they produce, the smell they generate, the signals they create, and the molecular guards they elaborate are some of the benefits they bestow on humans. After introducing the notion as to why microbes are an integral component in the development of humans, the book examines the genesis of the microbiome and describes how the resident bacteria work in partnership with the skin, digestive tract, sexual organs, mouth and lungs to execute vital physiological functions. It then discusses the diseases that are triggered by the disruption of the harmonious relationships amongst these diverse systems and provides microbial cures to ailments such as obesity and digestive complications. Finally, the book focuses on the future when the workings of the human microbes will be fully unravelled. Societal changes in health education, the establishment of the microbiome bank, the fight against hunger, space travel, designer traits and enhanced security are explained. Each chapter is accompanied by captivating illustrations and ends with a visual summary. Dr. Appanna has been researching for over 30 years on various aspects of microbial and human cellular systems. He is a professor of biochemistry and has also served as Department Chair and Dean of the Faculty at Laurentian University, Sudbury, Canada. The book is aimed at readers enrolled in medical, chiropractic, nursing, pharmacy, and health science programs. Practicing health-care professionals and continuing education learners will also find the content beneficial.

Zinc Signaling

Zinc Signaling
  • Author : Toshiyuki Fukada,Taiho Kambe
  • Publisher :Unknown
  • Release Date :2020-01-18
  • Total pages :413
  • ISBN : 9789811505577
GET BOOK HERE

Summary : This book, now in an extensively revised second edition, describes the crucial role of zinc signaling in biological processes on a molecular and physiological basis. Global leaders in the field review the latest knowledge, including the very significant advances in understanding that have been achieved since publication of the first edition. Detailed information is provided on all the essentials of zinc signaling, covering molecular aspects and the roles of zinc transporters, the zinc sensing receptor, and metallothioneins. Detection techniques for zinc signals, involving genetically encoded and chemical probes, are also described. The critical contributions of the zinc signal in maintaining health and the adverse consequences of any imbalance in the signal are then thoroughly addressed. Here, readers will find up-to-date information on the significance of the zinc signal in a wide range of conditions, including cardiovascular disorders, neurodegenerative diseases, diabetes, autoimmune diseases, inflammatory conditions, skin disease, osteoarthritis, and cancer. The book will be of value for researchers, clinicians, and advanced students.

Neuroimmune Diseases

Neuroimmune Diseases
  • Author : Hiroshi Mitoma,Mario Manto
  • Publisher :Unknown
  • Release Date :2019-08-13
  • Total pages :827
  • ISBN : 9783030195151
GET BOOK HERE

Summary : A translational overview of neuroimmune diseases for neuroscientists and clinicians that clarifies the pathological mechanisms underlying neuroimmune diseases and builds a comprehensive bridge between the latest research findings and their clinical implications in daily practice. The material is presented in two steps. The first section comprises a review of the pathogenic actions of immune cells in brain diseases. Here the authors discuss the mechanisms through which immune cells disrupt the functions of nerve cells. The second section explores the ways in which the brain becomes dysfunctional due to impaired nerve cell function. Based on pathogenesis, diagnostic and therapeutic strategies are discussed for each clinical category. The book will be invaluable for use in clinical practice of neuroimmune diseases