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3D Bioprinting

3D Bioprinting
  • Author : Ibrahim Tarik Ozbolat
  • Publisher :Unknown
  • Release Date :2016-11-21
  • Total pages :356
  • ISBN : 9780128030301
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Summary : 3D Bioprinting: Fundamentals, Principles and Applications provides the latest information on the fundamentals, principles, physics, and applications of 3D bioprinting. It contains descriptions of the various bioprinting processes and technologies used in additive biomanufacturing of tissue constructs, tissues, and organs using living cells. The increasing availability and decreasing costs of 3D printing technologies are driving its use to meet medical needs, and this book provides an overview of these technologies and their integration. Each chapter discusses current limitations on the relevant technology, giving future perspectives. Professor Ozbolat has pulled together expertise from the fields of bioprinting, tissue engineering, tissue fabrication, and 3D printing in his inclusive table of contents. Topics covered include raw materials, processes, machine technology, products, applications, and limitations. The information in this book will help bioengineers, tissue and manufacturing engineers, and medical doctors understand the features of each bioprinting process, as well as bioink and bioprinter types. In addition, the book presents tactics that can be used to select the appropriate process for a given application, such as tissue engineering and regenerative medicine, transplantation, clinics, or pharmaceutics. Describes all aspects of the bioprinting process, from bioink processing through design for bioprinting, bioprinting techniques, bioprinter technologies, organ printing, applications, and future trends Provides a detailed description of each bioprinting technique with an in-depth understanding of its process modeling, underlying physics and characteristics, suitable bioink and cell types printed, and major accomplishments achieved thus far Explains organ printing technology in detail with a step-by-step roadmap for the 3D bioprinting of organs from isolating stem cells to the post-transplantation of organs Presents tactics that can be used to select the appropriate process for a given application, such as tissue engineering and regenerative medicine, transplantation, clinics, or pharmaceutics

3D Bioprinting

3D Bioprinting
  • Author : Dong-Woo Cho,Byoung Soo Kim,Jinah Jang,Ge Gao,Wonil Han,Narendra K. Singh
  • Publisher :Unknown
  • Release Date :2019-12-04
  • Total pages :114
  • ISBN : 9783030322229
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Summary : This text advances fundamental knowledge in modeling in vitro tissues/organs as an alternative to 2D cell culture and animal testing. Prior to engineering in vitro tissues/organs,the descriptions of prerequisites (from pre-processing to post-processing) in modeling in vitro tissues/organs are discussed. The most prevalent technologies that have been widely used for establishing the in vitro tissue/organ models are also described, including transwell, cell spheroids/sheets, organoids, and microfluidic-based chips. In particular, the authors focus on 3D bioprinting in vitro tissue/organ models using tissue-specific bioinks. Several representative bioprinting methods and conventional bioinks are introduced. As a bioink source, decellularized extracellular matrix (dECM) are importantly covered, including decellularization methods, evaluation methods for demonstrating successful decellularization, and material safety. Taken together, the authors delineate various application examples of 3D bioprinted in vitro tissue/organ models especially using dECM bioinks.

Bioprinting

Bioprinting
  • Author : Maika G. Mitchell
  • Publisher :Unknown
  • Release Date :2017-02-17
  • Total pages :154
  • ISBN : 9780128094037
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Summary : Innovation is added value to a known process. Bioprinting: Techniques and Risks for Regenerative Medicine aims to stimulate a scientifically grounded, interdisciplinary, multiscale debate and exchange of ideas using the techniques described in the book. 3D printing and additive manufacturing evolved from within the field of Cell Biology will have the ability to recreate cells queried from large amounts of phenotypic and molecular data. Stem Cell biologists, biotechnologists and material engineers, as well as graduate students will greatly benefit from the practical knowledge and case examples provided throughout this book. Shows the possible risk of rejection of 3D printed cells. Contains bioprinting techniques in literature plus actual 3D files adapted and created by the author using several types of 3d printers Provides information on how to convert an existing 3-D printer to bioprinter using currently available techniques Describes the increased complexity of bioprinting compared to 3D- printing Discussion on how 3D printing and additive manufacturing offers the opportunity to 3D print an entire organ, reducing the associated costs of this process when using cells as bioink

3D Bioprinting and Nanotechnology in Tissue Engineering and Regenerative Medicine

3D Bioprinting and Nanotechnology in Tissue Engineering and Regenerative Medicine
  • Author : Lijie Grace Zhang,John P Fisher,Kam Leong
  • Publisher :Unknown
  • Release Date :2015-01-14
  • Total pages :392
  • ISBN : 9780128006641
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Summary : 3D Bioprinting and Nanotechnology in Tissue Engineering provides an in depth introduction to these two technologies and their industrial applications. Stem cells in tissue regeneration are covered, along with nanobiomaterials. Commercialization, legal and regulatory considerations are also discussed in order to help you translate nanotechnology and 3D printing-based products to the marketplace and the clinic. Dr. Zhang’s and Dr. Fishers’ team of expert contributors have pooled their expertise in order to provide a summary of the suitability, sustainability and limitations of each technique for each specific application. The increasing availability and decreasing costs of nanotechnologies and 3D printing technologies are driving their use to meet medical needs, and this book provides an overview of these technologies and their integration. It shows how nanotechnology can increase the clinical efficiency of prosthesis or artificial tissues made by bioprinting or biofabrication. Students and professionals will receive a balanced assessment of relevant technology with theoretical foundation, while still learning about the newest printing techniques. Includes clinical applications, regulatory hurdles, and risk-benefit analysis of each technology. This book will assist you in selecting the best materials and identifying the right parameters for printing, plus incorporate cells and biologically active agents into a printed structure Learn the advantages of integrating 3D printing and nanotechnology in order to improve the safety of your nano-scale materials for biomedical applications

3D Bioprinting for Reconstructive Surgery

3D Bioprinting for Reconstructive Surgery
  • Author : Daniel Thomas,Zita M. Jessop,Iain S. Whitaker
  • Publisher :Unknown
  • Release Date :2017-11-14
  • Total pages :450
  • ISBN : 9780081012161
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Summary : 3D Bioprinting for Reconstructive Surgery: Techniques and Applications examines the combined use of materials, procedures and tools necessary for creating structural tissue constructs for reconstructive purposes. Offering a broad analysis of the field, the first set of chapters review the range of biomaterials which can be used to create 3D-printed tissue constructs. Part Two looks at the techniques needed to prepare biomaterials and biological materials for 3D printing, while the final set of chapters examines application-specific examples of tissues formed from 3D printed biomaterials. 3D printing of biomaterials for tissue engineering applications is becoming increasingly popular due to its ability to offer unique, patient-specific parts—on demand—at a relatively low cost. This book is a valuable resource for biomaterials scientists, biomedical engineers, practitioners and students wishing to broaden their knowledge in the allied field. Discusses new possibilities in tissue engineering with 3D printing Presents a comprehensive coverage of the materials, techniques and tools needed for producing bioprinted tissues Reviews emerging technologies in addition to commercial techniques

3D Bioprinting

3D Bioprinting
  • Author : Jeremy M. Crook
  • Publisher :Unknown
  • Release Date :2020
  • Total pages :260
  • ISBN : 1071605208
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Summary : This volume explores the latest developments and contributions to the field of 3D bioprinting, and discusses its use for quality R&D and translation. The chapters in this book are divided into two parts: Part one covers generic themes in bioprinting to introduce novice readers to the field, while also providing experts with new and helpful information. Part two discusses protocols used to prepare, characterize, and print a variety of biomaterials, cells, and tissues. These chapters also emphasize methods used for printing defined and humanized constructs suitable for human tissue modelling in research and applicable to clinical product development. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, 3D Bioprinting: Methods and Protocols is a valuable resource for researchers and bioprinting laboratories/facilities interested in learning more about this rapidly evolving technology. .

Extrusion Bioprinting of Scaffolds for Tissue Engineering Applications

Extrusion Bioprinting of Scaffolds for Tissue Engineering Applications
  • Author : Daniel X. B. Chen
  • Publisher :Unknown
  • Release Date :2018-12-13
  • Total pages :171
  • ISBN : 9783030034603
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Summary : This book introduces readers to the theory and practice of extrusion bio-printing of scaffolds for tissue engineering applications. The author emphasizes the fundamentals and practical applications of extrusion bio-printing to scaffold fabrication, in a manner particularly suitable for those who wish to master the subject matter and apply it to real tissue engineering applications. Readers will learn to design, fabricate, and characterize tissue scaffolds to be created by means of extrusion bio-printing technology.

3D Bioprinting in Regenerative Engineering

3D Bioprinting in Regenerative Engineering
  • Author : Ali Khademhosseini,Gulden Camci-Unal
  • Publisher :Unknown
  • Release Date :2018-04-17
  • Total pages :385
  • ISBN : 9781315280479
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Summary : This book is comprehensive in nature with contributions by leading world experts in 3D bioprinting related to regenerative engineering. It includes history, incorporating the process and methods used in bioprinting. Significant sections will be reserved for the applications of the types of tissues generated by using bioprinting, along with an overview of different technologies used in bioprinting. In addition to equipment, the book also describes the different biomaterials and cells used in these approaches. Overall this is a book that includes both entry-level knowledge and advanced methods and techniques. Applications will emphasize engineering and clinical principles.

Bioprinting in Regenerative Medicine

Bioprinting in Regenerative Medicine
  • Author : Kursad Turksen
  • Publisher :Unknown
  • Release Date :2015-09-02
  • Total pages :140
  • ISBN : 9783319213866
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Summary : This volume presents the current state of laser-assisted bioprinting, a cutting edge tissue engineering technology. Nineteen chapters discuss the most recent developments in using this technology for engineering different types of tissue. Beginning with an overview, the discussion covers bioprinting in cell viability and pattern viability, tissue microfabrication to study cell proliferation, microenvironment for controlling stem cell fate, cell differentiation, zigzag cellular tubes, cartilage tissue engineering, osteogenesis, vessel substitutes, skin tissue and much more. Because bioprinting is on its way to becoming a dominant technology in tissue-engineering, Bioprinting in Regenerative Medicine is essential reading for those researching or working in regenerative medicine, tissue engineering or translational research. Those studying or working with stem cells who are interested in the development of the field will also find the information invaluable.

3D Bioprinting in Regenerative Engineering

3D Bioprinting in Regenerative Engineering
  • Author : Ali Khademhosseini,Gulden Camci-Unal
  • Publisher :Unknown
  • Release Date :2018-04-17
  • Total pages :385
  • ISBN : 9781315280479
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Summary : This book is comprehensive in nature with contributions by leading world experts in 3D bioprinting related to regenerative engineering. It includes history, incorporating the process and methods used in bioprinting. Significant sections will be reserved for the applications of the types of tissues generated by using bioprinting, along with an overview of different technologies used in bioprinting. In addition to equipment, the book also describes the different biomaterials and cells used in these approaches. Overall this is a book that includes both entry-level knowledge and advanced methods and techniques. Applications will emphasize engineering and clinical principles.

3D Bioprinting in Medicine

3D Bioprinting in Medicine
  • Author : Murat Guvendiren
  • Publisher :Unknown
  • Release Date :2019-08-02
  • Total pages :209
  • ISBN : 9783030239060
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Summary : This book provides current and emerging developments in bioprinting with respect to bioprinting technologies, bioinks, applications, and regulatory pathways. Topics covered include 3D bioprinting technologies, materials such as bioinks and bioink design, applications of bioprinting complex tissues, tissue and disease models, vasculature, and musculoskeletal tissue. The final chapter is devoted to clinical applications of bioprinting, including the safety, ethical, and regulatory aspects. This book serves as a go-to reference on bioprinting and is ideal for students, researchers and professionals, including those in academia, government, the medical industry, and healthcare.

3D Bioprinting for Reconstructive Surgery

3D Bioprinting for Reconstructive Surgery
  • Author : Daniel Thomas,Zita M. Jessop,Iain S. Whitaker
  • Publisher :Unknown
  • Release Date :2017-11-14
  • Total pages :450
  • ISBN : 9780081012161
GET BOOK HERE

Summary : 3D Bioprinting for Reconstructive Surgery: Techniques and Applications examines the combined use of materials, procedures and tools necessary for creating structural tissue constructs for reconstructive purposes. Offering a broad analysis of the field, the first set of chapters review the range of biomaterials which can be used to create 3D-printed tissue constructs. Part Two looks at the techniques needed to prepare biomaterials and biological materials for 3D printing, while the final set of chapters examines application-specific examples of tissues formed from 3D printed biomaterials. 3D printing of biomaterials for tissue engineering applications is becoming increasingly popular due to its ability to offer unique, patient-specific parts—on demand—at a relatively low cost. This book is a valuable resource for biomaterials scientists, biomedical engineers, practitioners and students wishing to broaden their knowledge in the allied field. Discusses new possibilities in tissue engineering with 3D printing Presents a comprehensive coverage of the materials, techniques and tools needed for producing bioprinted tissues Reviews emerging technologies in addition to commercial techniques

Biomimetic Medical Materials

Biomimetic Medical Materials
  • Author : Insup Noh
  • Publisher :Unknown
  • Release Date :2018-11-23
  • Total pages :399
  • ISBN : 9789811304453
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Summary : This volume outlines the current status in the field of biomimetic medical materials and illustrates research into their applications in tissue engineering. The book is divided into six parts, focusing on nano biomaterials, stem cells, tissue engineering, 3D printing, immune responses and intellectual property. Each chapter has its own introduction and outlines current research trends in a variety of applications of biomimetic medical materials. The biomimetic medical materials that are covered include functional hydrogels, nanoparticles for drug delivery and medicine, the 3D bioprinting of biomaterials, sensor materials, stem cell interactions with biomaterials, immune responses to biomaterials, biodegradable hard scaffolds for tissue engineering, as well as other important topics, like intellectual property. Each chapter is written by a team of experts. This volume attempts to introduce the biomimetic properties of biomedical materials within the context of our current understanding of the nanotechnology of nanoparticles and fibres and the macroscopic aspects of 3D bioprinting.

Study on Microextrusion-based 3D Bioprinting and Bioink Crosslinking Mechanisms

Study on Microextrusion-based 3D Bioprinting and Bioink Crosslinking Mechanisms
  • Author : Liliang Ouyang
  • Publisher :Unknown
  • Release Date :2019-08-10
  • Total pages :129
  • ISBN : 9789811394553
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Summary : This book presents a comprehensive study on microextrusion-based 3D bioprinting technologies for bioinks with various crosslinking mechanisms, chiefly focusing on the bioprinting process and bioink properties to provide readers with a better understanding of this state-of-the-art technology. Further, it summarizes a number of general criteria and research routes for microextrusion-based 3D bioprinting using three experimental studies based on shear-thinning, thermo-sensitive and non-viscous hydrogel bioinks. The book also presents sample applications in the areas of stem cells and cell matrix interaction. The book highlights pioneering results in the development of bioprinting technologies and bioinks, which were published in high-quality journals such as Advanced Materials, Biofabrication and ACS Biomaterials Science & Engineering. These include an in-situ crosslinking strategy that overcomes the viscosity limits for bioinks, which is virtually impossible using conventional strategies, and can be generalized for other bioink formulations.

Exam Prep for: 3d Bioprinting for Reconstructive Surgery

Exam Prep for: 3d Bioprinting for Reconstructive Surgery
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2021
  • Total pages :229
  • ISBN : 1230987654XX
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Summary :

Essentials of 3D Biofabrication and Translation

Essentials of 3D Biofabrication and Translation
  • Author : Anthony Atala,James J Yoo
  • Publisher :Unknown
  • Release Date :2015-07-17
  • Total pages :440
  • ISBN : 9780128010150
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Summary : Essentials of 3D Biofabrication and Translation discusses the techniques that are making bioprinting a viable alternative in regenerative medicine. The book runs the gamut of topics related to the subject, including hydrogels and polymers, nanotechnology, toxicity testing, and drug screening platforms, also introducing current applications in the cardiac, skeletal, and nervous systems, and organ construction. Leaders in clinical medicine and translational science provide a global perspective of the transformative nature of this field, including the use of cells, biomaterials, and macromolecules to create basic building blocks of tissues and organs, all of which are driving the field of biofabrication to transform regenerative medicine. Provides a new and versatile method to fabricating living tissue Discusses future applications for 3D bioprinting technologies, including use in the cardiac, skeletal, and nervous systems, and organ construction Describes current approaches and future challenges for translational science Runs the gamut of topics related to the subject, from hydrogels and polymers to nanotechnology, toxicity testing, and drug screening platforms

Aspiration-assisted Bioprinting

Aspiration-assisted Bioprinting
  • Author : Bugra Ayan
  • Publisher :Unknown
  • Release Date :2020
  • Total pages :229
  • ISBN : OCLC:1198448717
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Summary : Each year there are approximately 130,000 organ transplants conducted worldwide. Although a substantial number of organ transplantation, the current situation is far away from meeting the demand so that many people on the waitlist die each day. The supply of transplantable tissue faces the same complications and relies on a series of grafting techniques. Allografts (tissue from another human) and xenografts (tissue from an animal) are used to increase supply but these methods have a variety of issues. These problems include the possibility of rejection due to the presence of specific histocompatibility antigens that are targeted by antibodies in the recipient, and for the later there is a risk of microbial or viral transmission resulting in novel diseases. Autografts (tissue from the patient) eliminate the concerns of the previous two methods thanks to the use of genetically identical tissues. However, Autografts are only applicable in a small number of cases due to a lack of supply and large cost associated with the procedure. There is a clear need for cheap, accessible, and biocompatible tissues and organs for transplantation with a possible solution lying in bioprinting. Bioprinting offers a promising technology to fuse the high precision and time efficient qualities of additive manufacturing with tissue engineering to replicate morphogenesis with the ultimate goal of producing artificial tissues and organs on an industrial scale. This dissertation has centered on understanding, designing, and prototyping a new hybrid bioprinting process, called "Aspiration-assisted Bioprinting (AAB)," which enables to pick and precisely bioprint a wide of range of biologics, with dimensions in an order-of-magnitude range (80-800 [mu]m), into/onto a gel substrate with minimal cellular damage. In order to better understand the response of biologics to the bioprinting process, the underlying mechanism explaining the physical behavior of viscoelastic spheroids and their interactions with physical governing forces during aspiration, lifting and bioprinting were unveiled. Compared to existed methods, the approach that was explored in this dissertation facilitated the bioprinting of spheroids in higher positional precision and accuracy, ~11 and ~15% with respect to the spheroid size, respectively. In addition, it enabled bioprinting in 3D with flexibility of bioprinting of non-uniform, any-size spheroids into (I) a functional gel as a scaffold-based approach or (II) a sacrificial gel as a scaffold-free approach. The newly-developed AAB platform, modified from a Makerbot Replicator I (

Samsung Rising

Samsung Rising
  • Author : Geoffrey Cain
  • Publisher :Unknown
  • Release Date :2020-03-17
  • Total pages :416
  • ISBN : 9781101907269
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Summary : An explosive exposé of one of the biggest and most secretive companies in the world, Samsung, as the Korean juggernaut battles Apple and Sony to dominate the world of technology Based on years of reporting on Samsung for The Economist, The Wall Street Journal, and Time, from his base in South Korea, and his countless sources inside and outside the company, Geoffrey Cain offers a penetrating look behind the curtains of the biggest company nobody in America knows. Seen for decades in tech circles as a fast follower rather than an innovation leader, Samsung today has grown to become a market leader in the United States and around the globe. They have captured one quarter of the smartphone market and have been pushing the envelope on every front. Forty years ago, Samsung was a rickety Korean agricultural conglomerate that produced sugar, paper, and fertilizer, located in a backward country with a third-world economy. With the rise of the PC revolution, though, Chairman Lee Byung-chul began a bold experiment: to make Samsung a major supplier of computer chips. The multimillion- dollar plan was incredibly risky. But Lee, wowed by a young Steve Jobs, who sat down with the chairman to offer his advice, became obsessed with creating a tech empire. And in Samsung Rising, we follow Samsung behind the scenes as the company fights its way to the top of tech. It is one of Apple’s chief suppliers of technology critical to the iPhone, and its own Galaxy phone outsells the iPhone. Today, Samsung employs over 300,000 people (compared to Apple’s 80,000 and Google’s 48,000). The company’s revenues have grown more than forty times from that of 1987 and make up more than 20 percent of South Korea’s exports. Yet their disastrous recall of the Galaxy Note 7, with numerous reports of phones spontaneously bursting into flames, reveals the dangers of the company’s headlong attempt to overtake Apple at any cost. A sweeping insider account, Samsung Rising shows how a determined and fearless Asian competitor has become a force to be reckoned with.

Embedded Multimaterial Extrusion Bioprinting

Embedded Multimaterial Extrusion Bioprinting
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2021
  • Total pages :229
  • ISBN : OCLC:1051956094
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Summary : Embedded extrusion bioprinting allows for the generation of complex structures that otherwise cannot be achieved with conventional layer-by-layer deposition from the bottom, by overcoming the limits imposed by gravitational force. By taking advantage of a hydrogel bath, serving as a sacrificial printing environment, it is feasible to extrude a bioink in freeform until the entire structure is deposited and crosslinked. The bioprinted structure can be subsequently released from the supporting hydrogel and used for further applications. Combining this advanced three-dimensional (3D) bioprinting technique with a multimaterial extrusion printhead setup enables the fabrication of complex volumetric structures built from multiple bioinks. The work described in this paper focuses on the optimization of the experimental setup and proposes a workflow to automate the bioprinting process, resulting in a fast and efficient conversion of a virtual 3D model into a physical, extruded structure in freeform using the multimaterial embedded bioprinting system. It is anticipated that further development of this technology will likely lead to widespread applications in areas such as tissue engineering, pharmaceutical testing, and organs-on-chips.

Microarray Bioprinting Technology

Microarray Bioprinting Technology
  • Author : Moo-Yeal Lee
  • Publisher :Unknown
  • Release Date :2016-12-19
  • Total pages :175
  • ISBN : 9783319468051
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Summary : This book introduces key fundamentals of microarray bioprinting, including the required chip platforms and associated instruments/devices, experimental protocols for cell printing and biochemical- and cell-based assays, and several example applications. Various bioprinting approaches that allow for the rapid testing of hundreds of different cell culture conditions in combinations on a single chip are discussed in detail. Also covered is high-content, 3D cell-based imaging assays of tissue functions on miniaturized tissue constructs for high-throughput, predictive screening of drug efficacy and toxicity. This is an ideal book for graduate and postgraduate students in the field of biomedical engineering as well as scientists in the pharmaceutical industry. This book also: Broadens readers’ understanding of the principles of microarray bioprinting, chip platforms and associated instruments/devices, and surface chemistry for micropatterning of cells on the chip platform Covers the latest developments in printing cells in hydrogels and methods of gelation as well as printing other biological samples in aqueous solutions Illustrates the complete process for cell staining and high-content imaging of 3D cells on the chip and predicting human metabolism and toxicology on the chip

Biofabrication

Biofabrication
  • Author : Bertrand Guillotin,Muhammad Ali,Alexandre Ducom,Sylvain Catros,Virginie Keriquel,Agnès Souquet,Murielle Remy,Jean-Christophe Fricain,Fabien Guillemot
  • Publisher :Unknown
  • Release Date :2013-03-18
  • Total pages :288
  • ISBN : 9780128090534
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Summary : Laser-assisted bioprinting (LAB) is an emerging technology in the field of tissue engineering. Its physical mechanism makes it possible to print cells and liquid materials with a cell-level resolution. By giving tissue engineers control over cell density and organization of 3D tissue constructs, LAB holds much promise for fabricating living tissues with physiological functionality. After introducing the rationale of applying LAB to tissue engineering, we present exhaustively the physical parameters related to the laser-induced forward transfer technique (LIFT), which is implemented in LAB. These parameters are critical to controlling the cell printing process and must work together to print viable cell patterns with respect to cell-level histological organization and to high-throughput manufacturing. After describing the experimental requirements that should be considered to fabricate 3D tissues by LAB, we present some of the main breakthroughs, including multicomponent printing, 3D printing approaches, and bioprinting in vivo that may serve in tissue engineering and regenerative medicine.