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Biosensor Based Advanced Cancer Diagnostics

Biosensor Based Advanced Cancer Diagnostics
  • Author : Raju Khan,Arpana Parihar,S.K. Sanghi
  • Publisher :Unknown
  • Release Date :2021-09-01
  • Total pages :350
  • ISBN : 9780128236512
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Summary : Biosensor Based Advanced Cancer Diagnostics: From Lab to Clinics covers all available biosensor-based approaches and comprehensive technologies, along with their application in diagnosis, prognosis and therapeutic management of various diseases such as cancer, diabetes, Alzheimer's disease, toxicity in food products, brain and retinal diseases, cardiovascular diseases, and microbial infections. The book offers a view of recent advances that will be helpful for those designing new biosensor-based technologies in the field of medical science, engineering and biomedical technology. Biomedical engineers, researchers, molecular biologists, oncologists and clinicians tasked with the development of point-of-care devices, disease diagnostics and prognostics will find this resource very helpful. In addition, the book provides information on developing user-friendly, sensitive, stable, accurate, low cost and minimally invasive modalities that can be adopted from lab to clinics, while also presenting in-depth knowledge of disease biomarkers that can be exploited for designing and development of a range of biosensors. Covers the design and development of advanced platforms for the rapid diagnosis of cancerous biomarkers Takes a multidisciplinary approach to the development of sensitive transducers, nano-enabled advanced imaging, miniaturized analytical systems, and device packaging for point-of-care applications Offers insights into how to develop cost-effective diagnostics for early detection of cancer

Advanced Biosensors for Health Care Applications

Advanced Biosensors for Health Care Applications
  • Author : Dr. Inamuddin,Raju Khan,Ali Mohammad,Abdullah M. Asiri
  • Publisher :Unknown
  • Release Date :2019-06-15
  • Total pages :432
  • ISBN : 9780128165225
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Summary : Advanced Biosensors for Health Care Applications highlights the different types of prognostic and diagnostic biomarkers associated with cancer, diabetes, Alzheimer's disease, brain and retinal diseases, cardiovascular diseases, bacterial infections, as well as various types of electrochemical biosensor techniques used for early detection of the potential biomarkers of these diseases. Many advanced nanomaterials have attracted intense interests with their unique optical and electrical properties, high stability, and good biocompatibility. Based on these properties, advanced nanoparticles have been used as biomolecular carriers, signal producers, and signal amplifiers in biosensor design. Recent studies reported that there are several diagnostic methods available, but the major issue is the sensitivity and selectivity of these approaches. This book outlines the need of novel strategies for developing new systems to retrieve health information of patients in real time. It explores the potential of nano-multidisciplinary science in the design and development of smart sensing technology using micro-nanoelectrodes, novel sensing materials, integration with MEMS, miniaturized transduction systems, novel sensing strategy, that is, FET, CMOS, System-on-a-Chip (SoC), Diagnostic-on-a-Chip (DoC), and Lab-on-a-Chip (LOC), for diagnostics and personalized health-care monitoring. It is a useful handbook for specialists in biotechnology and biochemical engineering. Describes advanced nanomaterials for biosensor applications Relates the properties of available nanomaterials to specific biomarkers applications Includes diagnosis and electrochemical studies based on biosensors Explores the potential of nano-multidisciplinary science to design and develop smart sensing technologies Describes novel strategies for developing a new class of assay systems to retrieve the desired health information

Advances in Biomembranes and Lipid Self-Assembly

Advances in Biomembranes and Lipid Self-Assembly
  • Author : Ales Iglic,Ana Garcia-Saez,Michael Rappolt
  • Publisher :Unknown
  • Release Date :2020-04-24
  • Total pages :318
  • ISBN : 9780128209677
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Summary : Advances in Biomembranes and Lipid Self-assembly, Volume 31, formerly titled Advances in Planar Lipid Bilayers and Liposomes, provides a global platform for the study of cell membranes, lipid model membranes and lipid self-assemblies, from the micro- to the nanoscale. As planar lipid bilayers are widely studied due to their ubiquity in nature, this book presents research on their application in the formulation of biomimetic model membranes, and in the design of artificial dispersion of liposomes. Moreover, the book discusses how lipids self-assemble into a wide range of other structures, including micelles and the liquid crystalline hexagonal and cubic phases. Chapters in this volume present both original research and comprehensive reviews written by world leading experts and young researchers.

Biosensors and Nanotechnology

Biosensors and Nanotechnology
  • Author : Zeynep Altintas
  • Publisher :Unknown
  • Release Date :2017-12-18
  • Total pages :400
  • ISBN : 9781119065012
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Summary : General introduction to biosensors and recognition receptors -- Biomarkers in health care -- The use of nanomaterials and microfluidics in medical diagnostics -- SPR-based biosensor technologies in disease detection and diagnostics -- Piezoelectric-based biosensor technologies in disease detection and diagnostics -- Electrochemical-based biosensor technologies in disease detection and diagnostics -- MEMS-based cell counting methods -- Lab-on-a-chip platforms for disease detection and diagnosis -- Applications of quantum dots in biosensors and diagnostics -- Applications of molecularly imprinted nanostructures in biosensors and diagnostics -- Smart nanomaterial's : applications in biosensors and diagnostics -- Applications of magnetic nanomaterial's in biosensors and diagnostics -- Graphene applications in biosensors and diagnostics -- Optical biosensors and applications to drug discovery for cancer cases -- Biosensors for detection of anticancer drug-DNA interactions

Biomarkers and Biosensors for Cervical Cancer Diagnosis

Biomarkers and Biosensors for Cervical Cancer Diagnosis
  • Author : John Bosco Balaguru Rayappan,Jung Heon Lee
  • Publisher :Unknown
  • Release Date :2021-07-30
  • Total pages :229
  • ISBN : 9811625859
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Summary : This book highlights both conventional and nanomaterials-based biosensors for the detection of cervical cancers. It describes developments in the selective and sensitive electrochemical biosensors based on DNA for the early diagnosis of cervical cancer. Further, this book covers other nano-biosensing systems such as nano-thermometry-based sensing platforms, mechanical sensing platforms encompassing piezoelectric-based sensors, electrochemical impedance spectroscopy based on PEGylated arginine functionalized magnetic nanoparticles, and field-effect transistor-based platforms for the early detection of cervical cancer. Also, it presents conventional platforms such as vibrational spectroscopy and polymerase chain reaction techniques for the diagnosis of cervical cancer. Finally, it reviews currently available biomarkers for the early diagnosis of cervical cancer and presents strategies for developing novel biomarkers based on cellular and molecular approaches. As such, this book is a comprehensive resource for researchers and clinicians working in cervical cancer diagnostics.

Advanced Biosensors for Health Care Applications

Advanced Biosensors for Health Care Applications
  • Author : Dr. Inamuddin,Raju Khan,Ali Mohammad,Abdullah M. Asiri
  • Publisher :Unknown
  • Release Date :2019-06-15
  • Total pages :432
  • ISBN : 9780128165225
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Summary : Advanced Biosensors for Health Care Applications highlights the different types of prognostic and diagnostic biomarkers associated with cancer, diabetes, Alzheimer's disease, brain and retinal diseases, cardiovascular diseases, bacterial infections, as well as various types of electrochemical biosensor techniques used for early detection of the potential biomarkers of these diseases. Many advanced nanomaterials have attracted intense interests with their unique optical and electrical properties, high stability, and good biocompatibility. Based on these properties, advanced nanoparticles have been used as biomolecular carriers, signal producers, and signal amplifiers in biosensor design. Recent studies reported that there are several diagnostic methods available, but the major issue is the sensitivity and selectivity of these approaches. This book outlines the need of novel strategies for developing new systems to retrieve health information of patients in real time. It explores the potential of nano-multidisciplinary science in the design and development of smart sensing technology using micro-nanoelectrodes, novel sensing materials, integration with MEMS, miniaturized transduction systems, novel sensing strategy, that is, FET, CMOS, System-on-a-Chip (SoC), Diagnostic-on-a-Chip (DoC), and Lab-on-a-Chip (LOC), for diagnostics and personalized health-care monitoring. It is a useful handbook for specialists in biotechnology and biochemical engineering. Describes advanced nanomaterials for biosensor applications Relates the properties of available nanomaterials to specific biomarkers applications Includes diagnosis and electrochemical studies based on biosensors Explores the potential of nano-multidisciplinary science to design and develop smart sensing technologies Describes novel strategies for developing a new class of assay systems to retrieve the desired health information

Biosensors and Molecular Technologies for Cancer Diagnostics

Biosensors and Molecular Technologies for Cancer Diagnostics
  • Author : Keith E. Herold,Avraham Rasooly
  • Publisher :Unknown
  • Release Date :2012-05-29
  • Total pages :844
  • ISBN : 9781439841662
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Summary : Bridging the gap between research and clinical application, Biosensors and Molecular Technologies for Cancer Diagnostics explores the use of biosensors as effective alternatives to the current standard methods in cancer diagnosis and detection. It describes the major aspects involved in detecting and diagnosing cancer as well as the basic elements of biosensors and their applications in detection and diagnostics. The book addresses cancer molecular diagnostics, including genomic and proteomic approaches, from the perspective of biosensors and biodetection. It explains how to measure and understand molecular markers using biosensors and discusses the medical advantages of rapid and accurate cancer diagnostics. It also describes optical, electrochemical, and optomechanical biosensor technologies, with a focus on cancer analysis and the clinical utility of these technologies for cancer detection, diagnostics, prognostics, and treatment. Making biosensor technology more accessible to molecular biologists, oncologists, pathologists, and engineers, this volume advances the integration of this technology into mainstream clinical practice. Through its in-depth coverage of a range of biosensors, the book shows how they can play instrumental roles in the early molecular diagnosis of cancer.

Nanotechnology in Cancer Management

Nanotechnology in Cancer Management
  • Author : Kamil Reza Khondakar,Ajeet Kumar Kaushik
  • Publisher :Unknown
  • Release Date :2020-02-16
  • Total pages :462
  • ISBN : 0128181540
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Summary : Nanotechnology in Cancer Management: Precise Diagnostics toward Personalized Health Care provides a well-focused and comprehensive overview of technologies involved in early stage cancer diagnostics via detecting various cancer biomarkers, in-vitro and in-vivo. The book briefly describes the advancement is cancer biomarker research related to cancer diagnostics. It covers the fundamental aspects of various techniques especially transduction methodologies such as electrochemical, optical, magnetic etc. the advancements in selection methodologies using nanotechnology, electronics, etc, are also the focus of this book. It describes the approaches on how to make the various options cost-effective, scalable for clinical application, and user friendly as well as advancements in technology related to device miniaturization, performance improvement and point-of-care application also the part of this book. The future challenges and the prospects of the various techniques is also discussed and explains how the introduction of nanotechnology in cancer management in personalized manner becomes useful. Discusses nano-enabled sensing technology for rapid diagnostics targeted cancer needed for timely therapy Includes smart sensing materials such as smart electro-active nanomaterials, sensitive transducers development, nano-enabled advanced imaging, miniaturized analytical system, and device integration and interfacing for point-of-care application Describes each compartment involved in the development of an efficient cancer diagnostics system Focuses on fundamental and applied concepts of the technologies along with the exploring the related mechanisms proposed for diagnostics of cancer Enhances the fundamental understanding of the concepts and development of nanotechnology based analytical tools and novel techniques for early stage cancers diagnostics and its management

Immunosensors

Immunosensors
  • Author : Minhaz Uddin Ahmed,Mohammed Zourob,Eiichi Tamiya
  • Publisher :Unknown
  • Release Date :2019-08-21
  • Total pages :367
  • ISBN : 9781788018821
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Summary : Immunosensors are widely used and are particularly important for fast diagnosis of diseases in remote environments as well as point-of-care devices. In this book, expert scientists are covering a selection of high quality representative examples from the past five years explaining how this area has developed. It is a compilation of recent advances in several areas of immunosensors for multiple target analysis using laboratory based or point-of-care set-up, for example graphene-, ISFET- and nanostructure-based immunosensors, electrochemical magneto immunosensors and nanoimprinted immunosensors. Filling a gap in the literature, it showcases the multidisciplinary, innovative developments in this highly important area and provides pointers towards commercialisation. Delivering a single, comprehensive work, it appeals to graduate students and professional researchers across academia and industry.

Next Generation Point-of-care Biomedical Sensors Technologies for Cancer Diagnosis

Next Generation Point-of-care Biomedical Sensors Technologies for Cancer Diagnosis
  • Author : Pranjal Chandra,Yen Nee Tan,Surinder P. Singh
  • Publisher :Unknown
  • Release Date :2017-12-30
  • Total pages :396
  • ISBN : 9789811047268
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Summary : This book presents recent research on cancer detection methods based on nanobiosensors, which offer ultrasensitive point-of-care diagnosis. Several methods for diagnosing cancer have been discovered and many more are currently being developed. Conventional clinical approaches to detecting cancers are based on a biopsy followed by histopathology, or on the use of biomarkers (protein levels or nucleic acid content). Biopsy is the most widely used technique; however, it is an invasive technique and is not always applicable. Furthermore, biomarker-based detection cannot be relied on when the biomarkers are present in an extremely low concentration in the body fluids and in malignant tissues. Thus, in recent years highly sensitive and robust new cancer diagnosis techniques have been developed for clinical application, and may offer an alternative strategy for cancer diagnosis. As such, this book gathers the latest point-of-care cancer diagnostic methods and protocols based on biomedical sensors, microfluidics, and integrated systems engineering. It also discusses recent developments and diagnostics tests that can be conducted outside the laboratory in remote areas. These technologies include electrochemical sensors, paper-based microfluidics, and other kit-based diagnostic methods that can be adapted to bring cancer detection and diagnostics to more remote settings around the globe. Overall, the book provides students, researchers, and clinicians alike a comprehensive overview of interdisciplinary approaches to cancer diagnosis.

Advanced Bioelectronic Materials

Advanced Bioelectronic Materials
  • Author : Ashutosh Tiwari,Hirak K. Patra,Anthony P. F. Turner
  • Publisher :Unknown
  • Release Date :2015-10-09
  • Total pages :544
  • ISBN : 9781118998878
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Summary : This book covers the recent advances in the development of bioelectronics systems and their potential application in future biomedical applications starting from system design to signal processing for physiological monitoring, to in situ biosensing. Advanced Bioelectronic Materials contributions from distinguished international scholars whose backgrounds mirror the multidisciplinary readership ranging from the biomedical sciences, biosensors and engineering communities with diverse backgrounds, interests and proficiency in academia and industry. The readers will benefit from the widespread coverage of the current literature, state-of-the-art overview of all facets of advanced bioelectronics materials ranging from real time monitoring, in situ diagnostics, in vivo imaging, image-guided therapeutics, biosensors, and translational biomedical devices and personalized monitoring.

Bioengineering Innovative Solutions for Cancer

Bioengineering Innovative Solutions for Cancer
  • Author : Sylvain Ladame,Jason Chang
  • Publisher :Unknown
  • Release Date :2019-12-12
  • Total pages :393
  • ISBN : 9780128138878
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Summary : Bioengineering Innovative Solutions for Cancer bridges the gap between bioengineering and cancer biology. It focuses on a ‘bottom up’ understanding of the links between molecules, cells, tissues, organs, organisms, and health and functions—all within a bioengineering context. Chapters cover the main methods, technologies and devices that could help diagnose cancer sooner (e.g., ultrasensitive imaging and sensing technologies) and helpful treatments (e.g., new, more targeted therapies). The book takes an interdisciplinary approach that is ideal for those who need the latest information on design techniques and devices that help treat cancer using new, more targeted therapies. By covering the many different ways engineers can deliver innovative solutions to tackle cancer, this book is a valuable read for researchers who have an ambition to make an impact on people’s life in either an academic or industrial setting. Connects bioengineering and cancer biology, providing information on sensors, imaging, therapies and in-vitro models Presents the most comprehensive coverage in the field of cancer engineering to date Provides an academic introduction to (molecular) bioengineering for students, regardless of scientific background (math's, physics, chemistry, biology) Highlights the unmet medical needs for bioengineers and the main technological breakthroughs to cancer biologists

Biomarkers in Breast Cancer

Biomarkers in Breast Cancer
  • Author : Giampietro Gasparini,Daniel F. Hayes
  • Publisher :Unknown
  • Release Date :2008-01-17
  • Total pages :342
  • ISBN : 159259915X
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Summary : Expert laboratory and clinical researchers from around the world review how to design and evaluate studies of tumor markers and examine their use in breast cancer patients. The authors cover both the major advances in sophisticated molecular methods and the state-of-the-art in conventional prognostic and predictive indicators. Among the topics discussed are the relevance of rigorous study design and guidelines for the validation studies of new biomarkers, gene expression profiling by tissue microarrays, adjuvant systemic therapy, and the use of estrogen, progesterone, and epidermal growth factor receptors as both prognostic and predictive indicators. Highlights include the evaluation of HER2 and EGFR family members, of p53, and of UPA/PAI-1; the detection of rare cells in blood and marrow; and the detection and analysis of soluble, circulating markers.

Nanobiosensors

Nanobiosensors
  • Author : Aiguo Wu,Waheed S. Khan
  • Publisher :Unknown
  • Release Date :2020-06-02
  • Total pages :416
  • ISBN : 9783527345106
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Summary : Containing cutting edge research on the hot topic of nanobiosensor, this book will become highly read Biosensor research has recently re-emerged as most vibrant area in recent years particularly after the advent of novel nanomaterials of multidimensional features and compositions. Nanomaterials of different types and striking properties have played a positive role in giving the boost and accelerated pace to biosensors development technology. Nanobiosensors - From Design to Applications covers several aspects of biosensors beginning from the basic concepts to advanced level research. It will help to bridge the gap between various aspects of biosensors development technology and applications. It covers biosensors related material in broad spectrum such as basic concepts, biosensors & their classification, biomarkers & their role in biosensors, nanostructures-based biosensors, applications of biosensors in human diseases, drug detection, toxins, and smart phone based biosensors. Nanobiosensors - From Design to Applications will prove a source of inspiration for research on biosensors, their local level development and consequently using for practical application in different industries such as food, biomedical diagnosis, pharmaceutics, agriculture, drug discovery, forensics, etc. * Discusses the latest technology and advances in the field of nanobiosensors and their applications in human diseases, drug detection, toxins * Offers a broad and comprehensive view of cutting-edge research on advanced materials such as carbon materials, nitride based nanomaterials, metal and metal oxide based nanomaterials for the fast-developing nanobiosensors research * Goes to a wide scientific and industry audience Nanobiosensors - From Design to Applications is a resource for polymer chemists, spectroscopists, materials scientists, physical chemists, surface chemists, and surface physicists.

Nano-inspired Biosensors for Protein Assay with Clinical Applications

Nano-inspired Biosensors for Protein Assay with Clinical Applications
  • Author : Genxi Li
  • Publisher :Unknown
  • Release Date :2018-08-29
  • Total pages :378
  • ISBN : 9780128150542
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Summary : Nano-inspired Biosensors for Protein Assay with Clinical Applications introduces the latest developments in nano-inspired biosensing, helping readers understand both the fundamentals and frontiers in this rapidly advancing field. In recent decades, there has been increased interest in nano-inspired biosensors for clinical application. Proteins, e.g. antigen-antibody, tumor markers and enzymes are the most important target in disease diagnosis, and a variety of biosensing techniques and strategies have been developed for protein assay. This book brings together all the current literature on the most recent advances of protein analysis and new methodologies in designing new kinds of biosensors for clinical diagnostic use. Provides a single source of information on the latest developments in the field of biosensors for protein analysis and clinical diagnosis Focuses on biosensors fabricated with nanomaterials and nanotechnology Gives detailed methodologies for designing and fabricating nano-inspired biosensors

Biosensors and Cancer

Biosensors and Cancer
  • Author : Victor R. Preedy,Vinood Patel
  • Publisher :Unknown
  • Release Date :2012-07-27
  • Total pages :424
  • ISBN : 9781466558083
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Summary : Understanding the importance and application of biosensors is complicated by the diverse range of methods and applications. Furthermore, existing texts are somewhat technical in nature, making it difficult for the novice. This book disseminates information on biosensors in a readable way, suitable to a wide audience with varying levels of experience. Topics include optical imaging, surface plasmon resonance, microcantilevers, electrochemistry, aptamers, fluorescence, electrochemistry, nanobiosensors, and nanowires.

In-vitro Diagnostic Instrumentation

In-vitro Diagnostic Instrumentation
  • Author : Gerald E. Cohn,International Biomedical Optics Society,Society of Photo-optical Instrumentation Engineers
  • Publisher :Unknown
  • Release Date :2000
  • Total pages :228
  • ISBN : UOM:39015050114837
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Summary :

Commercial Biosensors and Their Applications

Commercial Biosensors and Their Applications
  • Author : Mustafa Kemal Sezgintürk
  • Publisher :Unknown
  • Release Date :2020-06-12
  • Total pages :374
  • ISBN : 9780128196854
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Summary : Commercial Biosensors and Their Applications: Clinical, Food, and Beyond offers professionals an in-depth look at some of the most significant applications of commercially available biosensor-based instrumentation in the clinical, food quality control, bioprocess monitoring, and bio threat fields. Featuring contributions by an international team of scientists, this book provides readers with an unparalleled opportunity to see how their colleagues around the world are using these powerful tools. This book is an indispensable addition to the reference libraries of biosensor technologists, analytical chemists, clinical chemists, biochemists, physicians, medical doctors, engineers, and clinical biochemists. The book discusses the need for portable, rapid, and smart biosensing devices and their use as cost-effective, in situ, real-time analytical tools in a variety of fields. Devotes several chapters to applications of biosensors to clinical samples, exploring how biosensors are currently used for in-home diabetes monitoring, point-of-care diagnostics, non-invasive sensing, and biomedical research Includes a section on food applications covering how biosensors can detect genetically modified organisms, toxins, allergens, hormones, microorganisms, species-specificity, pesticides, insecticides, and related components Discusses nanobiosensor and applications, including a chapter on nanotechnological approaches and materials in commercial biosensors

MicroRNA as Biomarkers in Cancer Diagnostics and Therapy

MicroRNA as Biomarkers in Cancer Diagnostics and Therapy
  • Author : Lorenzo F. Sempere
  • Publisher :Unknown
  • Release Date :2019-07-30
  • Total pages :166
  • ISBN : 9783039212491
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Summary : This book is a printed edition of the Special Issue MicroRNA as Biomarkers in Cancer Diagnostics and Therapy that was published in IJMS

Proof and Concepts in Rapid Diagnostic Tests and Technologies

Proof and Concepts in Rapid Diagnostic Tests and Technologies
  • Author : Shailendra K. Saxena
  • Publisher :Unknown
  • Release Date :2016-09-07
  • Total pages :172
  • ISBN : 9789535125808
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Summary : This book gives a comprehensive overview of the recent advancements and developments of rapid diagnostic tests (RDTs) and technologies, which are quite novel approaches and might be used as laboratory bench manual for the rapid diagnosis of the various disease conditions. The book focuses on various aspects and properties of RDTs, point-of-care tests (POCTs), quality control, assurance, calibration, safety, nano-/microfluidic technologies, and fusion with DNA technologies. I hope that this work might increase the interest in this field of research and that the readers will find it useful for their investigations, management, and clinical usage.

Nanobiosensors

Nanobiosensors
  • Author : Alexandru Grumezescu
  • Publisher :Unknown
  • Release Date :2016-12-20
  • Total pages :926
  • ISBN : 9780128043721
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Summary : Nanobiosensors: Nanotechnology in the Agri-Food Industry, Volume 8, provides the latest information on the increasing demand for robust, rapid, inexpensive, and safe alternative technologies that monitor, test, and detect harmful or potentially dangerous foods. Due to their high sensitivity and selectivity, nanobiosensors have attracted attention for their use in monitoring not only biological contaminants in food, but also potential chemical and physical hazards. This book offers a broad overview regarding the current progress made in the field of nanosensors, including cutting-edge technological progress and the impact of these devices on the food industry. Special attention is given to the detection of microbial contaminants and harmful metabolotes, such as toxins and hormones, which have a great impact on both humans and animal health and feed. Includes the most up-to-date information on nanoparticles based biosensors and quantum dots for biological detection Provides application methods and techniques for research analysis for bacteriological detection and food testing Presents studies using analytical tools to improve food safety and quality analysis