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Boorman's Pathology of the Rat

Boorman's Pathology of the Rat
  • Author : Andrew W. Suttie,Joel R. Leininger,Alys E. Bradley
  • Publisher :Unknown
  • Release Date :2017-12-18
  • Total pages :748
  • ISBN : 9780123914897
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Summary : Boorman’s Pathology of the Rat: Reference and Atlas, Second Edition, continues its history as the most comprehensive pathology reference on rat strains for researchers across science and medicine using rat models in the laboratory. It offers readers an added emphasis on the Sprague-Dawley and Wistar rat strains that is consistent with current research across academia, government, and industry. In addition, the book provides standard diagnostic criteria, basic content on histology, histological changes that result from drug toxicity and neoplasm, pathology terminology, and four-color photographs from the NTP archive and database. With updated references and photographs, as well as coverage of all rat strains, this book is not only the standard in the field, but also an invaluable resource for toxicologists, biologists, and other scientists engaged in regulatory toxicology who must make the transition from pathology results to the promulgation of meaningful regulations. Contains full, four color photographs from the NTP archive and database and coverage of all rat strains Provides an organ-by-organ and system-by-system approach that presents standard diagnostic criteria and basic content on histology and histological changes Includes comprehensive and detailed background incidence data Presents detailed descriptive content regarding changes in rat models during research

Boorman's Pathology of the Rat

Boorman's Pathology of the Rat
  • Author : Andrew W. Suttie,Joel R. Leininger,Alys E. Bradley
  • Publisher :Unknown
  • Release Date :2014-10-01
  • Total pages :688
  • ISBN : 0123914485
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Summary : Formerly titled Pathology of the Fischer Rat, Boorman's Pathology of the Rat continues to be the most comprehensive pathology reference and standard on rat strains. A vital resource for researchers across science and medicine using rat models in the laboratory, Boorman's Pathology of the Rat offers an added emphasis on the Sprague-Dawley and Wistar rat strains, in line with current research across academia, government, and industry. In addition, the book provides standard diagnostic criteria, basic content on histology, histological changes that result from drug toxicity and neoplasm, pathology terminology, and four-color photographs from the NTP archive and database. With updated references and photographs, as well as coverage of all rat strains, Boorman's Pathology of the Rat is the standard in the field, invaluable to toxicologists, biologists, and other scientists engaged in regulatory toxicology who must make the transition from pathology results to promulgation of meaningful regulations. Full-color photographs Coverage of all strains of rats Organ-by-organ and system-by-system approach Background incidence data Detailed descriptive content regarding changes in rat model during research

Pathology of the Fischer Rat

Pathology of the Fischer Rat
  • Author : Gary A. Boorman
  • Publisher :Unknown
  • Release Date :1990
  • Total pages :580
  • ISBN : 0121156400
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Summary : Studies in rodents of the toxicity and carcinogenicity of drugs, agricultural agents (e.g., pesticides and herbicides), environmental pollutants, industrial agents (e.g., solvents and intermediates), and other chemicals are the cornerstone of human safety evaluations in the development, use, and/or regulation of these agents. Those who perform the pathological evaluations from these studies need standard diagnostic criteria and pathology terminology. Pathology of the Fischer Rat is a comprehensive pathology reference text on the Fischer 344 rat, the strain widely used for safety evaluations and almost exclusively by the National Toxicology Program.****Every chapter follows the same format of introduction; embryology; normal anatomy, histology, and physiology; and congenital, degenerative, inflammatory and vascular, hyperplastic and neoplastic, miscellaneous, and toxicological lesions. The spectrum of spontaneous and treatment-related, neoplastic and nonneoplastic lesions found in each tissue is described and photographed.****The text is useful not only to pathologists but also to investigators from a variety of disciplines who use the rat as an animal model. It will also prove valuable to toxicologists, biologists, and other scientists engaged in regulatory toxicology who must make the transition from pathology results to promulgation of meaningful regulations.

Comparative Anatomy and Histology

Comparative Anatomy and Histology
  • Author : Piper M. Treuting,Suzanne M. Dintzis,Kathleen S. Montine
  • Publisher :Unknown
  • Release Date :2017-08-29
  • Total pages :570
  • ISBN : 9780128029190
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Summary : The second edition of Comparative Anatomy and Histology is aimed at the new rodent investigator as well as medical and veterinary pathologists who need to expand their knowledge base into comparative anatomy and histology. It guides the reader through normal mouse and rat anatomy and histology using direct comparison to the human. The side by side comparison of mouse, rat, and human tissues highlight the unique biology of the rodents, which has great impact on the validation of rodent models of human disease. Offers the only comprehensive source for comparing mouse, rat, and human anatomy and histology through over 1500 full-color images, in one reference work Enables human and veterinary pathologists to examine tissue samples with greater accuracy and confidence Teaches biomedical researchers to examine the histologic changes in their model rodents Experts from both human and veterinary fields take readers through each organ system in a side-by-side comparative approach to anatomy and histology - human Netter anatomy images along with Netter-style rodent images

The Laboratory Rat

The Laboratory Rat
  • Author : Mark A. Suckow,Steven H. Weisbroth,Craig L. Franklin
  • Publisher :Unknown
  • Release Date :2005-12-20
  • Total pages :928
  • ISBN : 0080454321
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Summary : The Laboratory Rat, Second Edition features updated information on a variety of topics including: rat genetics and genomics, both spontaneous and induced disease; state-of-the-art technology for housing and husbandry; occupational health, and experimental models. A premier source of information on the laboratory rat that will be of interest to veterinary and medical students, senior graduate, graduate students, post-docs and researchers who utilize animals in biomedical research. At least 50% new information than first edition Includes topics on rat genetics and genomics, occupational health, and experimental models The premier source of information on the laboratory rat

The Laboratory Rat

The Laboratory Rat
  • Author : Mark A. Suckow,F. Claire Hankenson,Ronald P. Wilson,Patricia L. Foley
  • Publisher :Unknown
  • Release Date :2019-11-10
  • Total pages :1180
  • ISBN : 9780128143391
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Summary : The third edition of The Laboratory Rat features updated information on a variety of topics, including rats as research models for basic and translational research in areas such as genomics, alcoholism, diabetes, metabolic syndrome, obesity, neuroscience, spinal cord injury, traumatic brain injury, regenerative medicine, and infectious disease. New information related to the husbandry and veterinary care of rats is provided including topics related to nutrition, reproduction, anesthesia and surgery, infectious and noninfectious disease, and the care of surgical and other fragile models. It is a premier source of information on the laboratory rat, this book will be of interest to veterinary and medical students, senior graduate students, postdocs and researchers who utilize animals in biomedical research. New chapters on the care of surgical and fragile models and on the use of rats in research areas such as alcoholism, regenerative medicine, spinal cord injury, traumatic brain injury, and others are included. All chapters were written by scientific and veterinary experts. This book condenses information from many sources on topics related to the care and use of rats in research. It is the premier source of information on the laboratory rat.

Toxicologic Pathology for Non-Pathologists

Toxicologic Pathology for Non-Pathologists
  • Author : Thomas J. Steinbach,Daniel J. Patrick,Mary Ellen Cosenza
  • Publisher :Unknown
  • Release Date :2019-10-31
  • Total pages :919
  • ISBN : 9781493997770
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Summary : This extensive volume began as a short course primarily geared toward toxicologists who want to expand their understanding of toxicologic pathology in order to be better study directors while also proving to be of great interest to other drug development scientists and regulatory reviewers. The overall goal is to help non-pathologists understand, contextualize, and communicate the pathology data and interpretations from the study pathologist in a practical and usable format. Within the book, readers will find an overview of general pathology concepts that include fundamental vocabulary and the basics of pathophysiological processes, along with numerous chapters devoted to pathology in specific organ systems as well as topics such as biomarkers, correlation of clinical pathology endpoints (chemistry and hematology) with microscopic changes, and well-known pathology findings for classes of toxic substances. Authoritative, practical, and comprehensive, Toxicologic Pathology for Non-Pathologists aims to help non-pathologists understand, converse in, and apply a basic understanding of pathology in their day-to-day careers.

Scientific Directory and Annual Bibliography

Scientific Directory and Annual Bibliography
  • Author : National Institutes of Health (U.S.),National Institutes of Health (U.S.).
  • Publisher :Unknown
  • Release Date :1990
  • Total pages :229
  • ISBN : UOM:39015023397725
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Summary : Presents the broad outline of NIH organizational structure, theprofessional staff, and their scientific and technical publications covering work done at NIH.

Companion Guide to Infectious Diseases of Mice and Rats

Companion Guide to Infectious Diseases of Mice and Rats
  • Author : National Research Council,Commission on Life Sciences,Institute for Laboratory Animal Research,Committee on Infectious Diseases of Mice and Rats
  • Publisher :Unknown
  • Release Date :1991-02-01
  • Total pages :108
  • ISBN : 9780309042833
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Summary : Committee on Infectious Diseases of Mice and Rats, National Research Council This companion to Infectious Diseases of Mice and Rats makes practical information on rodent diseases readily accessible to researchers. This volume parallels the three parts of the main volume. Part I, Principles of Rodent Disease Prevention, briefly examines the requirements for maintaining pathogen-free rodents, factors in designing health surveillance programs, and other laboratory management issues. Part II, Disease Agents, is an easy-to-use reference section, listing diagnosis and control methods, the potential for interference with research, and other factors for disease agents ranging from adenoviruses to tapeworms. It covers bacteria, viruses, fungi and common ectoparasites, and endoparasites. Part III, Diagnostic Indexes, presents alphabetical listings of clinical signs, pathology, and research complications and lists infectious agents that might be responsible for each.

Annual Plan for Fiscal Year ...

Annual Plan for Fiscal Year ...
  • Author : National Toxicology Program (U.S.)
  • Publisher :Unknown
  • Release Date :1985
  • Total pages :229
  • ISBN : UCSD:31822001823715
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Summary :

Endocrine System

Endocrine System
  • Author : T.C. Jones,U. Mohr,R.D. Hunt
  • Publisher :Unknown
  • Release Date :2012-12-06
  • Total pages :368
  • ISBN : 9783642967207
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Summary : The International Life Sciences Institute (ILSI) was creat ed to promote cooperative efforts toward solving critical health and safety questions involving foods, drugs, cosmet ics, chemicals, and other aspects of the environment. The officers and trustees believe that questions regarding health and safety are best resolved when government and industry rely on scientific investigations, analyses, and reviews by independent experts. Further, the scientific aspects of an issue should be examined and discussed on an international basis, separate from the political concerns of individual companies. The Institute is pleased to sponsor this set of monographs on pathology of laboratory animals. This project will help to improve the scientific application of the techniques of pathology to the evaluation of substances in our environ ment. The worldwide distribution of the authors, editors, and editorial board encourages the expectation that inter national communication and cooperation will also be strengthened. Alex Malaspina President International Life Sciences Institute Preface This book on the endocrine system is Volume I of a set of reference books on pathology of laboratory animals, prepared by the Interna tional Life Sciences Institute in response to recommendations from its Committee on Pathology and Toxicology. One aim is to provide infor mation which will be useful to pathologists, especially those involved in studies on the safety of foods, drugs, chemicals, and other sub stances in the environment.

Toxicology of the Kidney

Toxicology of the Kidney
  • Author : Ferdinand Rodriguez,Ferdinand Cohen,Christopher K. Ober,Lynden Archer
  • Publisher :Unknown
  • Release Date :2004-12-28
  • Total pages :1200
  • ISBN : 9780203646991
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Summary : The kidney plays a vital role in certain endocrine functions. Abnormalities caused by toxic chemicals or other interventions can have profound effects on these functions and consequently, on total functions. Toxicology of the Kidney, Third Edition is updated to reflect the latest research in this field and focuses on the correlation between anatomy

Pathology of Aging Rats

Pathology of Aging Rats
  • Author : Joe D. Burek
  • Publisher :Unknown
  • Release Date :1978
  • Total pages :230
  • ISBN : UCAL:B4514999
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Summary : In Dutch Inserted Between P.212 and P.(213).

Background Lesions in Laboratory Animals E-Book

Background Lesions in Laboratory Animals E-Book
  • Author : Elizabeth Fiona McInnes
  • Publisher :Unknown
  • Release Date :2011-10-24
  • Total pages :256
  • ISBN : 9780702049248
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Summary : Background Lesions in Laboratory Animals will be an invaluable aid to pathologists needing to recognize background and incidental lesions while examining slides taken from laboratory animals in acute and chronic toxicity studies, or while examining exotic species in a diagnostic laboratory. It gives clear descriptions and illustrations of the majority of background lesions likely to be encountered. Many of the lesions covered are unusual and can be mistaken for treatment-related findings in preclinical toxicity studies. The Atlas has been prepared with contributions from experienced toxicological pathologists who are specialists in each of the laboratory animal species covered and who have published extensively in these areas. over 600 high-definition, top-quality color photographs of background lesions found in rats, mice, dogs, minipigs, non-human primates, hamsters, guinea pigs and rabbits a separate chapter on lesions in the reproductive systems of all laboratory animals written by Dr Dianne Creasy, a world expert on testicular lesions in laboratory animals a chapter on common artifacts that may be observed in histological glass slides extensive references to each lesion described aging lesions encountered in all laboratory animal species, particularly in rats in mice which are used for carcinogenicity studies

Integument and Mammary Glands

Integument and Mammary Glands
  • Author : Thomas C. Jones,Ulrich Mohr,Ronald D. Hunt
  • Publisher :Unknown
  • Release Date :2012-12-06
  • Total pages :347
  • ISBN : 9783642837494
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Summary : The International Life Sciences Institute (ILSI) was estab lished in 1978 to stimulate and support scientific research and educational programs related to nutrition, toxicology, and food safety, and to encourage cooperation in these programs among scientists in universities, industry, and government agencies to assist in the resolution of health and safety issues. To supplement and enhance these efforts, ILSI has made a major commitment to supporting programs to harmon ize toxicologic testing, to advance a more uniform inter pretation of bioassay results worldwide, to promote a common understanding of lesion classifications, and to encourage wide discussion of these topics among scien tists. The Monographs on the Pathology of Laboratory Ani mals are designed to facilitate communication among those involved in the safety testing of foods, drugs, and chemicals. The complete set will cover all organ systems and is intended for use by pathologists, toxicologists, and others concerned with evaluating toxicity and carcinogen icity studies. The international nature of the project - as reflected in the composition of the editorial board and the diversity of the authors and editors - strengthens our ex pectations that understanding and cooperation will be im proved worldwide through the series. Alex Malaspina President International Life Sciences Institute Preface This book, on the integumentary system, is the seventh volume of a set prepared under the sponsorship of the International Life Sciences Institute (ILSI).

International Classification of Rodent Tumours: Male genital system

International Classification of Rodent Tumours: Male genital system
  • Author : Ulrich Mohr
  • Publisher :Unknown
  • Release Date :1992
  • Total pages :229
  • ISBN : UCSD:31822018363440
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Summary :

Comparative Anatomy and Histology

Comparative Anatomy and Histology
  • Author : Piper M. Treuting,Suzanne M. Dintzis
  • Publisher :Unknown
  • Release Date :2012-01
  • Total pages :461
  • ISBN : 9780123813619
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Summary : Comparative Anatomy and Histology: A Mouse and Human Atlas is aimed at the new mouse investigator as well as medical and veterinary pathologists who need to expand their knowledge base into comparative anatomy and histology. It guides the reader through normal mouse anatomy and histology using direct comparison to the human. The side by side comparison of mouse and human tissues highlight the unique biology of the mouse, which has great impact on the validation of mouse models of human disease. Print + Electronic product - E-book available on Elsevier's Expert Consult platform- through a scratch-off pin code inside the print book, customers will be able to access the full text online, perform quick searches, and download images at expertconsult.com Offers the first comprehensive source for comparing human and mouse anatomy and histology through over 600 full-color images, in one reference work Experts from both human and veterinary fields take readers through each organ system in a side-by-side comparative approach to anatomy and histology - human Netter anatomy images along with Netter-style mouse images Enables human and veterinary pathologists to examine tissue samples with greater accuracy and confidence Teaches biomedical researchers to examine the histologic changes in their mutant mice

Technical Report Series

Technical Report Series
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2013
  • Total pages :229
  • ISBN : UCBK:C069839070
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Summary :

Current Research in Animal Physiology

Current Research in Animal Physiology
  • Author : Victor S. Lamoureux
  • Publisher :Unknown
  • Release Date :2011-12-15
  • Total pages :318
  • ISBN : 9781926692791
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Summary : Animal physiology is the scientific study of how the bodies of animals function. How does an animal breathe, develop, eat and digest, reproduce, control its activities? The field encompasses the molecular, cellular, tissue and organ systems of animals. This book looks at an eclectic selection of studies in animal physiology, including how animals adapt to their physical environments, how human interaction can affect animal functioning, and much more.

National Toxicology Program : Annual Plan

National Toxicology Program : Annual Plan
  • Author : United States. Public Health Service
  • Publisher :Unknown
  • Release Date :1994
  • Total pages :229
  • ISBN : UOM:39015026226418
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Summary :

Digestive System

Digestive System
  • Author : Thomas Carlyle Jones,Ulrich Mohr,James A. Popp
  • Publisher :Unknown
  • Release Date :2013-11-11
  • Total pages :459
  • ISBN : 9783662259962
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Summary : This is the second edition of the third volume in the Monographs on Pathology of Laboratory Animals series. Since the first edition, new information has developed at a remarkable pace. Both editions propose standardized nomenclature that is being used internationally, gaining significant acceptance. The result is improved communications of pathologic data to regulatory agencies and in scientific publications worldwide. New information on the nature and variability of preneoplastic lesions in the liver of laboratory rodents is included in this edition. The book expands data on the accompanying changes in enzyme activity in affected liver cells. Spongiosis hepatis in the rat and its relation to spongiotic pericytoma are discussed thoroughly. Information on many other pathologic entities is brought up to date and new ones are added to this second edition, making it an even more useful and expanded reference text.