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Transcranial Brain Stimulation

Transcranial Brain Stimulation
  • Author : Carlo Miniussi,Walter Paulus,Paolo M. Rossini
  • Publisher :Unknown
  • Release Date :2012-12-03
  • Total pages :465
  • ISBN : 9781439875711
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Summary : Since the discovery of transcranial magnetic stimulation (TMS) and transcranial electrical stimulation (tES), these non-invasive brain stimulation (NIBS) techniques have been used to investigate the state of cortical excitability, and the excitability of the cortico-cortical and corticospinal pathways. In addition, these techniques have been found to induce neuroplasticity—a significant breakthrough in our understanding of the brain at work. Transcranial Brain Stimulation presents a wide range of possible brain stimulation applications and discusses what new information can be gained from using this technique on the dynamics of brain functions, hierarchical organization, and effective connectivity. Implications of recent findings related to the therapeutic application are discussed by an international group of leading experts, who present practical guidance on the use of each technique, and catalog the results of numerous TMS and tES studies on biological and behavioral effects.

Brain Stimulation

Brain Stimulation
  • Author : Irving Reti
  • Publisher :Unknown
  • Release Date :2015-05-11
  • Total pages :368
  • ISBN : 9781118568293
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Summary : Brain stimulation technologies are both tools to probe brain function and to provide therapeutic options for patients with neuropsychiatric disease where pharmacological options are not viable. Although the field has been in existence for over seventy years, research interest in brain stimulation has been on the rise particularly in the last two decades. Brain Stimulation: Methodologies and Interventions is an introduction to the field of brain stimulation technology and its applications. The book explores how brain stimulating technologies work in the context of brain pathways that mediate normal and abnormal brain function. Chapters cover neuroanatomy and activitydependent changes in neuronal function triggered by brain stimulation, as well as applications of brain stimulation technologies themselves, including noninvasive procedures that rely on convulsive or seizure therapeutics, and non-convulsive therapies such as magnetic and electrical brain stimulation. Authored by an international group of leaders in the field, Brain Stimulation is a valuable resource for both neuroscience researchers and clinicians. KEY POINTS • Includes introductory chapters on relevant neuroanatomy • Covers both invasive and noninvasive brain stimulation techniques • Explains basic mechanisms and therapeutic applications • Written by an international team of leaders in the field • Illustrated in full color

Brain Stimulation

Brain Stimulation
  • Author : Andres M. Lozano,Mark Hallett
  • Publisher :Unknown
  • Release Date :2013-11-11
  • Total pages :784
  • ISBN : 9780444534989
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Summary : The field of brain stimulation is expanding rapidly, with techniques such as DBS, TMS, and tDCS moving from the research community into clinical diagnosis and treatment. Clinical applications include treating disorders such as Parkinson's disease, dystonia, and even depression. The chapters of Brain Stimulation are written by leading international researchers and clinical specialists include coverage of techniques, modes of action and applications in physiology and therapeutics. The combination of research and clinical coverage will be of interest to neurologists, neurosurgeons, psychiatrists, neuroscientists, and health care workers. A comprehensive introduction and overview of deep brain stimulation (DBS) Coverage of DBS, transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) Details the basic science and research utility of DBS and clinical application

Deep Brain Stimulation

Deep Brain Stimulation
  • Author : Kendall H. Lee,Penelope S. Duffy,Allan J. Bieber
  • Publisher :Unknown
  • Release Date :2016-12-08
  • Total pages :486
  • ISBN : 9781315341095
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Summary : Deep brain stimulation (DBS) is a widely used therapy for movement disorders such as Parkinson's disease, essential tremor, and dystonia. Its therapeutic success has led to the application of DBS for an increasing spectrum of conditions. However, the fundamental relationships between neural activation, neurochemical transmission, and clinical outcomes during DBS are not well understood. Drawing on the clinical and research expertise of the Mayo Clinic Neural Engineering Laboratories, this book addresses the history of therapeutic electrical stimulation of the brain, its current application and outcomes, and theories about its underlying mechanisms. It reviews research on measures of local stimulation–evoked neurochemical release, imaging research on stimulation-induced neural circuitry activation, and the state of the art on closed-loop feedback devices for stimulation delivery.

Pediatric Brain Stimulation

Pediatric Brain Stimulation
  • Author : Adam Kirton,Donald L. Gilbert
  • Publisher :Unknown
  • Release Date :2016-07-08
  • Total pages :500
  • ISBN : 9780128020388
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Summary : Pediatric Brain Stimulation: Mapping and Modulating the Developing Brain presents the latest on this rapidly expanding field that has seen an exponential growth in publications over the past 10 years. Non-invasive modalities like TMS can painlessly map and measure complex neurophysiology in real patients. Neuromodulatory applications like rTMS and tDCS carry increasingly proven therapeutic applications. Rapidly advancing technological methodologies are increasing opportunities and indications. Despite all these benefits, applications in the more plastic developing brains of children are only just emerging. This book provides a comprehensive overview of brain stimulation in children. Chapters include Transcranial Magnetic Stimulation (TMS) fundamentals, brain stimulation in pediatric neurological conditions, and invasive brain stimulation. The main audience for this research will be those interested in applying brain stimulation technologies to advance clinical research and patient care, although a wide variety of clinicians and scientist will find this to be a valuable reference on brain stimulation with specific chapters on a variety of conditions. Provides an overview of recent findings and knowledge of pediatric brain stimulation and the developing brain Edited by renowned leaders in the field of pediatric brain stimulation Presents a great resource for basic and clinical scientists and practitioners in neuroscience, neurology, neurosurgery, and psychiatry

Deep Brain Stimulation for Neurological Disorders

Deep Brain Stimulation for Neurological Disorders
  • Author : Toru Itakura
  • Publisher :Unknown
  • Release Date :2014-08-28
  • Total pages :208
  • ISBN : 9783319084763
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Summary : Chronic electrical stimulation of the brain has demonstrated excellent outcomes in patients with Parkinson’s disease and has recently also been applied to various other neurological diseases. This comprehensive, up-to-date textbook will meet the needs of all who wish to learn more about the application of deep brain stimulation and will provide a sound basis for safe and accurate surgery. The book comprises two main parts, the first of which presents relevant anatomical and functional background information on the basal ganglia, thalamus and other brain structures as well as on the mechanism of brain stimulation. The second part describes clinical studies on deep brain stimulation, covering results in a range of movement disorders and psychiatric diseases and also important aspects of instrumentation and technique. The authors are outstanding scientists and experts in the field from across the world.

Brain Stimulation in Psychiatry

Brain Stimulation in Psychiatry
  • Author : Charles H. Kellner
  • Publisher :Unknown
  • Release Date :2012-05-31
  • Total pages :158
  • ISBN : 9780521172554
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Summary : An authoritative, concise, how-to guide to the various brain stimulation treatments used in psychiatry.

Deep Brain Stimulation

Deep Brain Stimulation
  • Author : Shilpa Chitnis,Pravin Khemani,Michael S. Okun
  • Publisher :Unknown
  • Release Date :2020
  • Total pages :256
  • ISBN : 9780190647209
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Summary : "Tremor is an involuntary movement characterized by a rhythmic oscillation about a fixed point or trajectory. It can be classified based on its clinical features or underlying cause. Tremor was the first approved indication for DBS in the U.S. We now have almost three decades of experience of tremor treatment with DBS. Essential tremor (ET) is the most frequent movement disorder occurring at a frequency of about 5 times that of PD. ET commonly has an autosomal dominant transmission pattern with incomplete penetrance, therefore sporadic cases are not at all uncommon. In ET, most patients suffer from tremor of the hands and arms; approximately 40% suffer from head and 20% from voice tremor. The majority of candidates for functional neurosurgery belong to the ET subgroup which is commonly characterized by severe action or postural tremor that impairs function and quality of life to the extent that the risks, costs and inconvenience of DBS treatment are justified. Unilateral procedures (targeting the thalamus contralateral to the dominant and/or most affected hand) are commonly performed, though bilateral procedures should be considered when limb tremor is severe bilaterally, or when head, voice, or trunk tremors cause significant disability"--

The Stimulated Brain

The Stimulated Brain
  • Author : Roi Cohen Kadosh
  • Publisher :Unknown
  • Release Date :2014-06-01
  • Total pages :568
  • ISBN : 9780124047129
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Summary : The Stimulated Brain—which garnered an Honorable Mention for Biomedicine & Neuroscience at the 2015 PROSE Awards from the Association of American Publishers—presents the first integration of findings on brain stimulation from different research fields with a primary focus on Transcranial Electrical Stimulation (tES), one of the most frequently used noninvasive stimulation methods. The last decade has witnessed a significant increase in the amount of research exploring how noninvasive brain stimulation can not only modulate but also enhance cognition and brain functions. However, although Transcranial Magnetic Stimulation (TMS) and particularly tES have the potential to become more widely applicable techniques (as they come with none of the risks associated with deep brain stimulation) the reference literature on these neurotechnologies has been sparse. This resource provides a broad survey of current knowledge, and also marks future directions in cognitive and neuro-enhancement. It expands our understanding of basic research findings from animals and humans, including clear translational benefits for applied research and the therapeutic use of noninvasive brain stimulation methods. The book's coverage includes a primer that paves the way to a more advanced knowledge of tES and its physiological basis; current research findings on cognitive and neuro-enhancement in animals and typical and atypical human populations, such as neurological patients; and discussions of future directions, including specific neuroethical issues and pathways for collaboration and entrepreneurialism. The Stimulated Brain is the first book to provide a comprehensive understanding of different aspects of noninvasive brain stimulation that are critical for scientists, clinicians, and those who are interested in “stimulating their minds by exploring this fascinating field of research. Honorable Mention for Biomedicine & Neuroscience in the 2015 PROSE Awards from the Association of American Publishers The only reference on the market to focus on transcranial electrical stimulation (tES) Coverage across technical, historical, and application topics makes this the single, comprehensive resource for researchers and students Edited book with chapters authored by international leaders in the fields of medicine, neuroscience, psychology, and philosophy—providing the broadest, most expert coverage available

Deep Brain Stimulation for Parkinson's Disease

Deep Brain Stimulation for Parkinson's Disease
  • Author : Gordon H. Baltuch,Matthew B. Stern
  • Publisher :Unknown
  • Release Date :2007-03-19
  • Total pages :372
  • ISBN : 1420019759
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Summary : Considered the largest breakthrough in the treatment of Parkinson's disease in the past 40 years, Deep Brain Stimulation (DBS) is a pioneering procedure of neurology and functional neurosurgery, forging enormous change and growth within the field. The first comprehensive text devoted to this surgical therapy, Deep Brain Stimulation for Parkinson's

Electrical Brain Stimulation for the Treatment of Neurological Disorders

Electrical Brain Stimulation for the Treatment of Neurological Disorders
  • Author : Bahman Zohuri,Patrick J. McDaniel
  • Publisher :Unknown
  • Release Date :2019-08-27
  • Total pages :550
  • ISBN : 9781000527391
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Summary : In this book, Electrical Brain Stimulation for the Treatment of Neurological Disorders, the authors present their embodiment for a closed loop, feedback controlled, non-invasive application of electrical stimulation of the brain to enhance individual/group performance or to treat neurological disorders. Using a combination of modeling and experimental work, the authors have developed a unique approach to the field in combination with new technology from the perspectives of electro-magnetic and electrical engineering, computation of image processing, machine learning and neural networking, and in conjunction with the medicine of neurology and understanding of neuron behavior. They claim that non-invasive brain stimulation (NIBS) will provide new treatment methods with much greater simplicity, lower cost, improved safety, and in some cases, possibly greater effectiveness than well-established pharmacological methods or more recent invasive electrical deep brain stimulation (DBS) techniques. The authors explain their techniques and the results of their experimental studies and assert that the application of tailored and individualized control of their approach can be combined with other therapy methods to treat neurological disorders while minimizing or even eliminating the use of pharmaceuticals.

Non-Invasive Brain Stimulation: New Prospects in Cognitive Neurorehabilitation

Non-Invasive Brain Stimulation: New Prospects in Cognitive Neurorehabilitation
  • Author : Carlo Professor Miniussi,Giuseppe Professor Vallar
  • Publisher :Unknown
  • Release Date :2012-12-06
  • Total pages :216
  • ISBN : 9781135849153
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Summary : Cognitive deficits are a common consequence of neurological disease, and there is evidence that specific cognitive training may be effective in rehabilitation. Behavioural dysfunction following neurological disease constitutes one of the major causes of disability worldwide, exerts a major impact on the daily life of affected individuals, and their families, also with a financial burden both for patients, and the society in general. Therefore, the adequate treatment of cognitive dysfunction is a much relevant issue, with social and economical implications, over and above the neuropsychological problem per se. Several investigations emphasise the fact that interacting with neural activity, by means of cortical stimulation, can affect cognitive performance. A number of studies have reported enhanced performance in specific cognitive tasks in patients with several types of neurological disease, after receiving Non Invasive Brain Stimulation (NIBS) to specific cortical areas, namely: Transcranial Magnetic Stimulation, and transcranial Electrical Stimulation. In general, the evidence highlights the possibility of inducing changes in cortical excitability, which, in turn, may lead to a plastic reorganization of dysfunctional networks, responsible for the impaired cognitive functions. Despite these advances, a number of important questions remain open, regarding the use of stimulation techniques in cognitive rehabilitation. This special issue puts together international leading experts in the field, to review and discuss recent advances as to whether NIBS techniques alone, or combined with behavioural cognitive rehabilitation, can lead to performance enhancements, and why. The issue is timely and promises to have a huge impact across many domains of clinical and basic neuroscience.

Deep Brain Stimulation Programming

Deep Brain Stimulation Programming
  • Author : Erwin B. Montgomery, Jr., MD
  • Publisher :Unknown
  • Release Date :2010-04-13
  • Total pages :208
  • ISBN : 9780199890019
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Summary : Deep Brain Stimulation (DBS) is a remarkable therapy for an expanding range of neurological and psychiatric disorders. In many cases it is better than best medical therapy and succeeds even when brain transplants fail. Yet despite the remarkable benefits, many physicians and healthcare professionals seem hesitant to embrace this therapy. Post-operative programming of the DBS systems seems unfamiliar, even mysterious, and is viewed as difficult and time consuming. However, DBS programming is rational and can be efficient and effective if one understands the basing underlying concepts of electronics, electrophysiology, and the relevant regional anatomy. Even these principles can be relatively easy to grasp. The book helps the reader to obtain an intuitive understanding of the basic principles of electronics, electrophysiology and the relevant regional anatomy through the use of readily understood metaphors and numerous illustrations. In addition a number of tools are provided including algorithms to ensure efficient and thorough programming. Forms are provided to help with documentation. In addition, DBS related research provides a remarkable tool to understand how the brain works and what happens in diseases such as Parkinson's disease. Already long cherished theories of the pathophysiology of Parkinson's disease must be abandoned. Indeed, these DBS derived insights suggest fundamental revisions of theories of brain function are in order. The book provides an introduction to where some of the new theories may lead particularly with the growing awareness of the importance of oscillations in the brain's activities. The brain has more in common with electrical devices, such as computers, than it does to a stew of chemicals. DBS operates at the electrical level in the brain, which is fundamental to how the brain creates, manipulates and conveys information and may indeed be fundamental to the misinformation the results in the dysfunction related to disorders of the brain. For downloadable forms and other relevant material, please visit: http://www.uab.edu/DBS_PrinciplesAndPractice

Deep Brain Stimulation

Deep Brain Stimulation
  • Author : Damiaan Denys,Matthijs Feenstra,Rick Schuurman
  • Publisher :Unknown
  • Release Date :2012-09-13
  • Total pages :300
  • ISBN : 9783642309908
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Summary : This book examines present developments and the future possibilities of deep brain stimulation therapy for patients with therapy-refractory psychiatric disorders. Presents clinical applications and animal research, and offers a chapter on ethical issues.

Intraoperative Neurophysiological Monitoring for Deep Brain Stimulation

Intraoperative Neurophysiological Monitoring for Deep Brain Stimulation
  • Author : Erwin B. Montgomery, Jr.,Erwin B. Montgomery (Jr.)
  • Publisher :Unknown
  • Release Date :2014-07-16
  • Total pages :402
  • ISBN : 9780199351008
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Summary : A thorough understanding of electricity, electronics, biophysics, neurophysiology, and neuroanatomy is important to render more tractable, and otherwise complex, electrophysiologically-based targeting in the brain during operative manipulations. Most importantly, electrophysiological monitoring requires controlling the movement of electrons in electronic circuits in order to prevent irreversible damage. This new textbook presents a fundamental discussion of electrons, the forces moving these electrons, and the electrical circuits controlling these forces. The forces that allow recording and analysis also permeate the environment producing interference, such as noise and artifacts. Intraoperative Neurophysiological Monitoring for Deep Brain Stimulation discusses how to avoid or suppress noise and artifacts for the most successful surgical outcome.

Twenty Things to Know about Deep Brain Stimulation

Twenty Things to Know about Deep Brain Stimulation
  • Author : Erwin B. Montgomery, Jr.
  • Publisher :Unknown
  • Release Date :2015-01-30
  • Total pages :296
  • ISBN : 9780199338825
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Summary : Twenty Things to Know About Deep Brain Stimulation is an extensive and in-depth critical analysis of the field of Deep Brain Stimulation (DBS) from what many may consider a revolutionary perspective. This book demonstrates the unique nature and incredible promise of DBS and shows how it is unparalleled as a therapeutic intervention. Dr. Montgomery provides an epistemic analysis of the presuppositions, assumptions and fallacies underlying current clinical understanding of DBS as well as the physiology and pathophysiology affected by DBS. Reviews of the safety and efficacy for a number of conditions, patient selections and issues in the post-operative management are also included. Given the revolutionary potential and the complexity of DBS in an ever changing healthcare delivery context, the ethics of DBS are discussed in detail.

Deep Brain Stimulation Management

Deep Brain Stimulation Management
  • Author : William J. Marks, Jr
  • Publisher :Unknown
  • Release Date :2015-09-03
  • Total pages :229
  • ISBN : 9781316033623
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Summary : This concise guide to deep brain stimulation (DBS) outlines a practical approach to the use of this paradigm-shifting therapy for neurologic and psychiatric disorders. Fully revised throughout, the new edition provides extensive information about the application of DBS to movement disorders, and includes new chapters on DBS to treat epilepsy and psychiatric conditions. With the evolution of surgical techniques for DBS lead implantation, a brand new section focused on interventional MRI approaches is also included. All key aspects of DBS practice are covered, including patient selection, device programming to achieve optimal symptom control, long-term management, and troubleshooting. It is a guide to be kept in the clinic and consulted in the course of managing patients being considered for, or treated with, DBS. With contributions from some of the most experienced clinical leaders in the field, this is a must-have reference guide for any clinician working with DBS patients.

Brain Stimulation

Brain Stimulation
  • Author : David T. Brocker,Warren M. Grill
  • Publisher :Unknown
  • Release Date :2013-11-11
  • Total pages :784
  • ISBN : 9780128080078
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Summary : Deep brain stimulation is a remarkable therapy that has mainstreamed electrical stimulation of the brain for the treatment of neurological dysfunction. To appreciate the mechanisms of deep brain stimulation, we need to understand the excitability of neural tissue. Here, we survey the pertinent principles of electrical excitation in the brain. The amount of current delivered and the tissue conductivity together determine the strength and extent of potentials generated by stimulation. The electrode–tissue interface is an important junction where electrical charge carriers in the stimulation hardware are converted to ionic charge carriers in the tissue. Cathodic stimulation tends to depolarize neural elements more easily than anodic stimulation. The current–distance relationship describes how the amount of current needed to excite an axon increases as a function of its distance from the electrode. This relationship also depends on the axon’s diameter because large-diameter axons are excited more easily than small-diameter axons. For a given axon, the strength–duration relationship describes the inverse relationship between threshold current amplitude and pulse duration. Specific stimulation parameters must be considered to avoid stimulation-induced tissue damage. A strong foundation in these principles facilitates understanding of the complex effects of electrical stimulation in the brain.

Deep Brain Stimulation in Neurological and Psychiatric Disorders

Deep Brain Stimulation in Neurological and Psychiatric Disorders
  • Author : Daniel Tarsy,Jerrold Lee Vitek,Philip Starr,Michael Okun
  • Publisher :Unknown
  • Release Date :2008-06-04
  • Total pages :601
  • ISBN : 1597453609
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Summary : This important book discusses today’s most current and cutting-edge applications of Deep Brain Stimulation (DBS). The book begins with reviews of the functional anatomy and physiology of motor and nonmotor aspects of the basal ganglia and their connections which underlie the application of DBS to neurological and psychiatric disorders. This is followed by proposed mechanisms of action of DBS based on functional neuroimaging and neurophysiologic studies in animals and man.

Deep Brain Stimulation

Deep Brain Stimulation
  • Author : William S. Anderson,The Society for Innovative Neuroscience in Neurosurgery
  • Publisher :Unknown
  • Release Date :2019-05-10
  • Total pages :190
  • ISBN : 9781626237988
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Summary : The one-stop resource on deep brain stimulation for functional neurosurgeons! Deep brain stimulation (DBS) is used to modulate dysfunctional circuits in the brain with stimulation pulses applied to specific target areas of the brain. Globally, DBS procedures have been most commonly performed for Parkinson's disease and essential tremor, but there are now new and growing research efforts studying DBS for psychiatric disorders and epilepsy. Deep Brain Stimulation: Techniques and Practices written by the Society for Innovative Neuroscience in Neurosurgery along with Dr. William S. Anderson and distinguished experts presents the latest DBS approaches. The book begins with a history of DBS, general frame-based techniques, patient selection primarily for movement disorders, multidisciplinary collaboration, and ethical considerations. Subsequent chapters detail diverse technologies and disease-specific treatment for Parkinson's disease, essential tremor, dystonia, OCD, epilepsy, major depression, Tourette syndrome, emerging psychiatric indications, and pediatric applications. Key highlights Lead placement techniques utilizing currently available customized platforms and robotics Microelectrode recording and image-based direct targeting with MRI and CT to enhance lead placement Lesioning methods including radiofrequency, and MR-guided focused ultrasound Discussion of recent innovations in tractography to delineate white matter tracts in the brain and closed loop stimulation DBS has helped thousands of patients with intractable conditions, allowing for a programmable therapy with durable treatment effect. This remarkable guide provides the essentials for functional neurosurgeons to pursue intraoperative research opportunities in this growing subspecialty and incorporate DBS into clinical practice.

Deep Brain Stimulation

Deep Brain Stimulation
  • Author : Peter Bain
  • Publisher :Unknown
  • Release Date :2009-03-05
  • Total pages :210
  • ISBN : 9780199543717
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Summary : This handbook provides an overview of the use of deep brain stimulation (DBS) for the treatment of movement disorders as well as an introduction to the developing area of DBS for the management of psychiatric disease.