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Cellular and Molecular Pathobiology of Cardiovascular Disease

Cellular and Molecular Pathobiology of Cardiovascular Disease
  • Author : Monte Willis,Jonathon W. Homeister,James R. Stone
  • Publisher :Unknown
  • Release Date :2013-12-23
  • Total pages :338
  • ISBN : 9780124055254
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Summary : Cellular and Molecular Pathobiology of Cardiovascular Disease focuses on the pathophysiology of common cardiovascular disease in the context of its underlying mechanisms and molecular biology. This book has been developed from the editors' experiences teaching an advanced cardiovascular pathology course for PhD trainees in the biomedical sciences, and trainees in cardiology, pathology, public health, and veterinary medicine. No other single text-reference combines clinical cardiology and cardiovascular pathology with enough molecular content for graduate students in both biomedical research and clinical departments. The text is complemented and supported by a rich variety of photomicrographs, diagrams of molecular relationships, and tables. It is uniquely useful to a wide audience of graduate students and post-doctoral fellows in areas from pathology to physiology, genetics, pharmacology, and more, as well as medical residents in pathology, laboratory medicine, internal medicine, cardiovascular surgery, and cardiology. Explains how to identify cardiovascular pathologies and compare with normal physiology to aid research Gives concise explanations of key issues and background reading suggestions Covers molecular bases of diseases for better understanding of molecular events that precede or accompany the development of pathology

Cardiovascular Pathology

Cardiovascular Pathology
  • Author : L. Maximilian Buja,Jagdish Butany
  • Publisher :Unknown
  • Release Date :2015-11-11
  • Total pages :830
  • ISBN : 9780128004593
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Summary : Cardiovascular Pathology, Fourth Edition, provides users with a comprehensive overview that encompasses its examination, cardiac structure, both normal and physiologically altered, and a multitude of abnormalities. This updated edition offers current views on interventions, both medical and surgical, and the pathology related to them. Congenital heart disease and its pathobiology are covered in some depth, as are vasculitis and neoplasias. Each section has been revised to reflect new discoveries in clinical and molecular pathology, with new chapters updated and written with a practical approach, especially with regards to the discussion of pathophysiology. New chapters reflect recent technological advances with cardiac devices, transplants, genetics, and immunology. Each chapter is highly illustrated and covers contemporary aspects of the disease processes, including a section on the role of molecular diagnostics and cytogenetics as specifically related to cardiovascular pathology. Customers buy the Print + Electronic product together! Serves as a contemporary, all-inclusive guide to cardiovascular pathology for clinicians and researchers, as well as clinical residents and fellows of pathology, cardiology, cardiac surgery, and internal medicine Offers new organization of each chapter to enable uniformity for learning and reference: Definition, Epidemiology, Clinical Presentation, Pathogenesis/Genetics, Light and Electron Microscopy/Immunohistochemistry, Differential Diagnosis, Treatment and Potential Complications Features six new chapters and expanded coverage of the normal heart and blood vessels, cardiovascular devices, congenital heart disease, tropical and infectious cardiac disease, and forensic pathology of the cardiovascular system Contains 400+ full color illustrations and an online image collection facilitate research, study, and lecture slide creation

Molecular Pathology

Molecular Pathology
  • Author : William B. Coleman,Gregory J. Tsongalis
  • Publisher :Unknown
  • Release Date :2017-11-09
  • Total pages :802
  • ISBN : 9780128027875
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Summary : As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, Molecular Pathology, Second Edition stands out as the most comprehensive textbook where molecular mechanisms represent the focus. It is uniquely concerned with the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine. The Second Edition of Molecular Pathology has been thoroughly updated to reflect seven years of exponential changes in the fields of genetics, molecular, and cell biology which molecular pathology translates in the practice of molecular medicine. The textbook is intended to serve as a multi-use textbook that would be appropriate as a classroom teaching tool for biomedical graduate students, medical students, allied health students, and others (such as advanced undergraduates). Further, this textbook will be valuable for pathology residents and other postdoctoral fellows that desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. In addition, this textbook is useful as a reference book for practicing basic scientists and physician scientists that perform disease-related basic science and translational research, who require a ready information resource on the molecular basis of various human diseases and disease states. Explores the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease Explains the practice of “molecular medicine and the translational aspects of molecular pathology Teaches from the perspective of “integrative systems biology Enhanced digital version included with purchase

Post-Genomic Cardiology

Post-Genomic Cardiology
  • Author : José Marín-García
  • Publisher :Unknown
  • Release Date :2011-04-28
  • Total pages :688
  • ISBN : 0080554547
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Summary : Recent advances in molecular and cellular biology have markedly changed our understanding of the heart, and this is having tremendous ramifications for the clinician. This unique reference offers a comprehensive and critical evaluation of this contribution in the field of cardiovascular molecular medicine providing the reader with a sense of new directions in which molecular medicine might be applied. It begins with a detailed primer that makes readily accessible recent molecular, genetic and cellular techniques. Rounding out the coverage of this exciting field are critical and comprenhesive discussions on the use of molecular, genetic and cellular techniques used to identify the etiology and pathophysiology of specific cardiac diseases. * Discusses diagnostic and therapeutic options available not only in the adult and aging individuals but also in infants/children * Numerous illustrations and flow-charts * Explans cutting-edge molecular techniques, including analysis of mitochondria, their role in cardiac dysfunction and updated analysis of Cardioprotection and Metabolic Syndrome * Presentation of recent translational studies for the treatment of cardiovascular diseases is included (e.g., gene therapy, pharmacological treatments and stem cell transplantation)

Pathophysiology and Pharmacotherapy of Cardiovascular Disease

Pathophysiology and Pharmacotherapy of Cardiovascular Disease
  • Author : Gowraganahalli Jagadeesh,Pitchai Balakumar,Khin Maung-U
  • Publisher :Unknown
  • Release Date :2015-05-06
  • Total pages :1342
  • ISBN : 9783319159614
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Summary : The present book covers the basic principles of cardiovascular physiology, pathophysiology and advanced pharmacology with particular emphasis on cellular mechanisms of drug action. It provides an update on the progress made in several aspects of cardiovascular diseases so that it might kindle scientists and clinicians alike in furthering basic and translational research. In addition, the book is expected to fill imperative gaps in understanding and optimally treating cardiovascular disease.

Cellular and Molecular Pathobiology of Cardiovascular Disease

Cellular and Molecular Pathobiology of Cardiovascular Disease
  • Author : Monte Willis,Jonathon W. Homeister,James R. Stone
  • Publisher :Unknown
  • Release Date :2013-12-23
  • Total pages :338
  • ISBN : 9780124055254
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Summary : Cellular and Molecular Pathobiology of Cardiovascular Disease focuses on the pathophysiology of common cardiovascular disease in the context of its underlying mechanisms and molecular biology. This book has been developed from the editors' experiences teaching an advanced cardiovascular pathology course for PhD trainees in the biomedical sciences, and trainees in cardiology, pathology, public health, and veterinary medicine. No other single text-reference combines clinical cardiology and cardiovascular pathology with enough molecular content for graduate students in both biomedical research and clinical departments. The text is complemented and supported by a rich variety of photomicrographs, diagrams of molecular relationships, and tables. It is uniquely useful to a wide audience of graduate students and post-doctoral fellows in areas from pathology to physiology, genetics, pharmacology, and more, as well as medical residents in pathology, laboratory medicine, internal medicine, cardiovascular surgery, and cardiology. Explains how to identify cardiovascular pathologies and compare with normal physiology to aid research Gives concise explanations of key issues and background reading suggestions Covers molecular bases of diseases for better understanding of molecular events that precede or accompany the development of pathology

Endocrinology of the Heart in Health and Disease

Endocrinology of the Heart in Health and Disease
  • Author : Jonathan C. Schisler,Charles H Lang,Monte Willis
  • Publisher :Unknown
  • Release Date :2016-10-19
  • Total pages :378
  • ISBN : 9780128031124
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Summary : Endocrinology of the Heart in Health and Disease: Integrated, Cellular, and Molecular Endocrinology of the Heart covers the traditional concepts of cardio-endocrinology, the role of the various hormone systems, both in health and disease, therapeutic implications, and other recent advances in the various fields represented. The book explores how cardiac hormones are changed in various cardiac pathologies and the recent success that has been uncovered in their therapeutic use. Additional focus is placed on how the heart responds both physiologically and pathophysiologically to a plethora of circulating hormones, reinforcing the importance of the heart as a target of numerous endocrine systems, such as the brain, renal, and adipose. Significant advances have come from basic, clinical, and translational research from a multiplicity of investigators with diverse backgrounds. The book features over 200 photomicrographs, diagrams of molecular relationships, and tables that complement and support the text. It is aimed at a wide audience, including graduate students and post-doctoral fellows in a wide array of biomedical departments and PhD programs (e.g. Pathology, Physiology, Genetics, Pharmacology, Molecular Biology, and Cell Biology) related to the endocrine and cardiovascular sciences curricula, as well as medical residents in pathology, laboratory medicine, internal medicine, and cardiology. Develops the concept of the heart as both an endocrine organ and an endocrine target, exploring the endocrine function of the heart in both health and disease Explains how the levels of several cardiac hormones are changed in various cardiac pathologies and how some hormones can be used therapeutically Offers a single resource on cardio-endocrine disease which collates and curates the wide range of advances being made in the areas of molecular biology, biochemistry, physiology, and pathology

Cardiovascular Diseases

Cardiovascular Diseases
  • Author : Y. Robert Li
  • Publisher :Unknown
  • Release Date :2015-04-06
  • Total pages :512
  • ISBN : 9780470915370
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Summary : Even though there has been improvement in treatment and significant reduction in mortality rate, cardiovascular disease remains one of the leading causes of death around the world. Drug therapy continues to rank high as a way to manage heart disease – making cardiovascular pharmacology a key part of medical education and drug development research. This book addresses the needs of these students and researchers by systematically integrating essentials, advances, and clinical correlations for cardiovascular drugs. The author, who has over two decades of experience teaching this topic, covers both the fundamentals and most recent advances in the pharmacology of cardiovascular drugs, as well as their integrated applications in the management of individual cardiovascular diseases. In addition, the text presents evidence-based pharmacotherapeutics in the management of common cardiovascular diseases and conditions that include dyslipidemias, hypertension, ischemic heart disease, heart failure, cardiac arrhythmias, and ischemic stroke. Written in an accessible style and consistent format, the book covers both the fundamentals and advances in the pharmacology of cardiovascular drugs, as well as their integrated applications in the management of individual cardiovascular diseases. • Blends basic and clinical sciences needed to effectively understand and treat cardiovascular diseases • Facilitates understanding of drug action and mechanism by covering physiology / pathophysiology and pharmacology • Includes guidelines and algorithms for pharmacotherapeutic management of cardiovascular diseases • Uses case presentations and study questions to enhance understanding of the material • Serves as a resource for pharmaceutical and medical students and researchers interested in cardiovascular issues

Essential Concepts in Molecular Pathology

Essential Concepts in Molecular Pathology
  • Author : William B. Coleman,Gregory J. Tsongalis
  • Publisher :Unknown
  • Release Date :2010-02-16
  • Total pages :462
  • ISBN : 008092218X
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Summary : This streamlined "essential" version of the Molecular Pathology (2009) textbook extracts key information, illustrations and photographs from the main textbook in the same number and organization of chapters. It is aimed at teaching students in courses where the full textbook is not needed, but the concepts included are desirable (such as graduate students in allied health programs or undergraduates). It is also aimed at students who are enrolled in courses that primarily use a traditional pathology textbook, but need the complementary concepts of molecular pathology (such as medical students). Further, the textbook will be valuable for pathology residents and other postdoctoral fellows who desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. Offers an essential introduction to molecular genetics and the "molecular" aspects of human disease Teaches from the perspective of "integrative systems biology," which encompasses the intersection of all molecular aspects of biology, as applied to understanding human disease In-depth presentation of the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease using histopathology. "Traditional" pathology section provides state-of-the-art information on the major forms of disease, their pathologies, and the molecular mechanisms that drive these diseases. Explains the practice of "molecular medicine" and the translational aspects of molecular pathology: molecular diagnostics, molecular assessment, and personalized medicine Each chapter ends with Key Summary Points and Suggested Readings

Cell and Tissue Based Molecular Pathology E-Book

Cell and Tissue Based Molecular Pathology E-Book
  • Author : Raymond R. Tubbs,Mark H. Stoler
  • Publisher :Unknown
  • Release Date :2008-09-22
  • Total pages :452
  • ISBN : 9781437719482
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Summary : This volume in the Foundations in Diagnostic Pathology Series packs today's most essential cell and tissue base molecular pathology into a compact, high-yield format! It focuses on the state of the art in practical validated molecular diagnostics as applied across the fields of surgical pathology and cytology. With an emphasis on current, clinically valid, and diagnostically important applications today and in the near future, you can be assured you’re getting the most up-to-date, authoritative coverage available. Its pragmatic, well-organized approach, nearly 250 full-color illustrations, and at-a-glance boxes and tables make the information you need easy to access. Practical and affordable, this resource is ideal for study and review as well as everyday clinical practice! Offers detailed discussions on today’s technologies to help you select the best test for case evaluation. Presents recognized molecular pathologists who convey the most current information, keeping you on the cusp of your field. Features nearly 250 full-color illustrations that present important pathologic features, enabling you to form a differential diagnosis and compare your findings with actual cases. Uses a consistent, user-friendly format, including at-a-glance boxes and tables for easy reference.

Cardiovascular

Cardiovascular
  • Author : Dylan V. Miller,Monica P. Revelo
  • Publisher :Unknown
  • Release Date :2018-02-22
  • Total pages :552
  • ISBN : 032359560X
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Summary : Part of the highly regarded Diagnostic Pathology series, this updated volume by Drs. Dylan V. Miller and Monica P. Revelo is an ideal point-of-care reference for the accurate diagnosis of complex cardiovascular specimens. Concise, focused chapters, supported by tables, diagrams, radiographs, and photographs, provide essential information to keep you up to date with new cardiac devices, the increased use of molecular panels, WHO updates, and much more. Hundreds of images, including photomicrographs, spectacular gross images, electron micrographs, and vivid medical illustrations Separate sections on specimens encountered in the settings of biopsy, surgical resection, and autopsy Time-saving reference features include bulleted text, tables of diagnostic criteria, annotated images, and an extensive index Thoroughly updated content includes new cardiac devices that require pathologic evaluation; increasing volumes of established devices in surgical and autopsy specimens; the increasing use of molecular panels in the evaluation of cardiomyopathy, aortic diseases, sudden cardiac death, and myocarditis; and updates from an international consensus on cardiac tumor reporting (ICCR) A new chapter on TAVR (transcatheter) valves, plus updates to the chapters on prosthetic valves, LVADs, stents (including a description of 2 new methods of preparing sections that can be done in any histology lab), and more A new section, Autopsy Evaluation of Cardiovascular Disease, includes 9 chapters from the Diagnostic Pathology: Hospital Autopsy volume Updates from the new edition of the WHO blue book for cardiac tumors Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

The Molecular Pathology of Autoimmune Diseases

The Molecular Pathology of Autoimmune Diseases
  • Author : Argyrios N Theofilopoulos,Constantin A. Bona
  • Publisher :Unknown
  • Release Date :2002-12-06
  • Total pages :1200
  • ISBN : 9057026457
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Summary : Remarkable advances have been made in the pathogenesis of autoimmunity, such as with bone marrow transplantation, which is becoming a powerful strategy in treating certain life-threatening diseases. The Molecular Pathology of Autoimmune Diseases is a concise and centralized resource for information on the topic, with a special focus on the molecular and genetic basis of these disorders. Dozens of international experts devote themselves to illuminating the reader in this volume, with discussions on the basic aspects of autoimmune processes to systemic and organ-specific diseases. This volume is an invaluable reference to students and professionals in immunology and related fields.

Molecular Pathology in Clinical Practice

Molecular Pathology in Clinical Practice
  • Author : Debra G.B. Leonard
  • Publisher :Unknown
  • Release Date :2016-02-02
  • Total pages :1001
  • ISBN : 9783319196749
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Summary : This authoritative textbook offers in-depth coverage of all aspects of molecular pathology practice and embodies the current standard in molecular testing. Since the successful first edition, new sections have been added on pharmacogenetics and genomics, while other sections have been revised and updated to reflect the rapid advances in the field. The result is a superb reference that encompasses molecular biology basics, genetics, inherited cancers, solid tumors, neoplastic hematopathology, infectious diseases, identity testing, HLA typing, laboratory management, genomics and proteomics. Throughout the text, emphasis is placed on the molecular variations being detected, the clinical usefulness of the tests and important clinical and laboratory issues. The second edition of Molecular Pathology in Clinical Practice will be an invaluable source of information for all practicing molecular pathologists and will also be of utility for other pathologists, clinical colleagues and trainees.

Translational Research in Coronary Artery Disease

Translational Research in Coronary Artery Disease
  • Author : Wilbert S. Aronow,John Arthur McClung
  • Publisher :Unknown
  • Release Date :2015-10-29
  • Total pages :244
  • ISBN : 9780128026052
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Summary : Translational Research in Coronary Artery Disease: Pathophysiology to Treatment covers the entire spectrum of basic science, genetics, drug treatment, and interventions for coronary artery disease. With an emphasis on vascular biology, this reference fully explains the fundamental aspects of coronary artery disease pathophysiology. Included are important topics, including endothelial function, endothelial injury, and endothelial repair in various disease states, vascular smooth muscle function and its interaction with the endothelium, and the interrelationship between inflammatory biology and vascular function. By providing this synthesis of current research literature, this reference allows the cardiovascular scientist and practitioner to access everything they need from one source. Provides a concise summary of recent developments in coronary and vascular research, including previously unpublished data Summarizes in-depth discussions of the pathobiology and novel treatment strategies for coronary artery disease Provides access to an accompanying website that contains photos and videos of noninvasive diagnostic modalities for evaluation of coronary artery disease

Diagnostic Molecular Pathology

Diagnostic Molecular Pathology
  • Author : William B. Coleman,Gregory J. Tsongalis
  • Publisher :Unknown
  • Release Date :2016-10-05
  • Total pages :582
  • ISBN : 9780128011577
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Summary : Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing is organized around disease types (genetic disease, infectious disease, neoplastic disease, among others). In each section, the authors provide background on disease mechanisms and describe how laboratory testing is built on knowledge of these mechanisms. Sections are dedicated to general methodologies employed in testing (to convey the concepts reflected in the methods), and specific description of how these methods can be applied and are applied to specific diseases are described. The book does not present molecular methods in isolation, but considers how other evidence (symptoms, radiology or other imaging, or other clinical tests) is used to guide the selection of molecular tests or how these other data are used in conjunction with molecular tests to make diagnoses (or otherwise contribute to clinical workup). In addition, final chapters look to the future (new technologies, new approaches) of applied molecular pathology and how discovery-based research will yield new and useful biomarkers and tests. Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing contains exercises to test readers on their understanding of how molecular diagnostic tests are utilized and the value of the information that can be obtained in the context of the patient workup. Readers are directed to an ancillary website that contains supplementary materials in the form of exercises where decision trees can be employed to simulate actual clinical decisions. Focuses on the menu of molecular diagnostic tests available in modern molecular pathology or clinical laboratories that can be applied to disease detection, diagnosis, and classification in the clinical workup of a patient Explains how molecular tests are utilized to guide the treatment of patients in personalized medicine (guided therapies) and for prognostication of disease Features an ancillary website with self-testing exercises where decision trees can be employed to simulate actual clinical decisions Highlights new technologies and approaches of applied molecular pathology and how discovery-based research will yield new and useful biomarkers and tests

Stem Cell and Gene Therapy for Cardiovascular Disease

Stem Cell and Gene Therapy for Cardiovascular Disease
  • Author : Emerson C. Perin,Leslie W. Miller,Doris Taylor,James T. Willerson
  • Publisher :Unknown
  • Release Date :2015-08-21
  • Total pages :538
  • ISBN : 9780128018637
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Summary : Stem Cell and Gene Therapy for Cardiovascular Disease is a state-of-the-art reference that combines, in one place, the breadth and depth of information available on the topic. As stem cell and gene therapies are the most cutting-edge therapies currently available for patients with heart failure, each section of the book provides information on medical trials from contributors and specialists from around the world, including not only what has been completed, but also what is planned for future research and trials. Cardiology researchers, basic science clinicians, fellows, residents, students, and industry professionals will find this book an invaluable resource for further study on the topic. Provides information on stem and gene therapy medical trials from contributors and specialists around the world, including not only what has been completed, but also what is planned for future research and trials Presents topics that can be applied to allogeneic cells, mesenchymal cells, gene therapy, cardiomyoctyes, iPS cells, MAPC's, and organogenesis Covers the three areas with the greatest clinical trials to date: chronic limb ischemia, chronic angina, and acute MI Covers the prevailing opinions on how to harness the body’s natural repair mechanisms Ideal resource for cardiology researchers, basic science clinicians, fellows, residents, students, and industry professionals

Endothelium and Cardiovascular Diseases

Endothelium and Cardiovascular Diseases
  • Author : Protasio Lemos Da Luz,Peter Libby,Francisco Rafael Martins Laurindo,Antonio Carlos Palandri Chagas
  • Publisher :Unknown
  • Release Date :2018-02-03
  • Total pages :758
  • ISBN : 9780128125519
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Summary : Endothelium and Cardiovascular Diseases: Vascular Biology and Clinical Syndromes provides an in-depth examination of the role of endothelium and endothelial dysfunction in normal vascular function, and in a broad spectrum of clinical syndromes, from atherosclerosis, to cognitive disturbances and eclampsia. The endothelium is a major participant in the pathophysiology of diseases, such as atherosclerosis, diabetes and hypertension, and these entities are responsible for the largest part of cardiovascular mortality and morbidly. Over the last decade major new discoveries and concepts involving the endothelium have come to light. This important reference collects this data in an easy to reference resource. Written by known experts, and covering all aspects of endothelial function in health and disease, this reference represents an assembly of recent knowledge that is essential to both basic investigators and clinicians. Provides a complete overview of endothelial function in health and diseases, along with an assessment of new information Includes coverage of groundbreaking areas, including the artificial LDL particle, the development of a new anti-erectile dysfunction agent, a vaccine for atherosclerosis, coronary calcification associated with red wine, and the interplay of endoplasmic reticulum/oxidative stress Explores the genetic features of endothelium and the interaction between basic knowledge and clinical syndromes

Hypoxia and Anoxia

Hypoxia and Anoxia
  • Author : Kusal Das,Mallanagouda Shivanagouda Biradar
  • Publisher :Unknown
  • Release Date :2018-12-12
  • Total pages :144
  • ISBN : 9781789848281
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Summary : The molecular deprivation of oxygen is manifested by hypoxia, a deficiency of oxygen and anoxia, or the absence of oxygen supply to the tissues. This book entitled Hypoxia and Anoxia will cover a broad range of understanding on hypoxia and anoxia from molecular mechanisms to pathophysiology. Hypoxia and anoxia stimulate multiple systems through specific cell signal transduction pathways and regulate several transcriptional factors like HIF-1, REST to encode genes for VEGF, Epo, etc. This book will also highlight different types of hypoxia and anoxia along with their impact on apoptosis, cardiovascular pathophysiology, and glucose regulatory mechanisms. This book will be a ready reckoner to give a deep understanding of the oxygen-sensing environment in vivo for researchers, academicians, and clinicians throughout the world.

Hypoxia and Human Diseases

Hypoxia and Human Diseases
  • Author : Jing Zheng,Chi Zhou
  • Publisher :Unknown
  • Release Date :2017-02-01
  • Total pages :454
  • ISBN : 9789535128953
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Summary : This book contains a total of 21 chapters, each of which was written by experts in the corresponding field. The objective of this book is to provide a comprehensive and updated overview of cellular and molecular mechanisms underlying hypoxia's impacts on human health, as well as current advances and future directions in the detection, recognition, and management of hypoxia-related disorders. This collection of articles provides a clear update in the area of hypoxia research for biomedical researchers, medical students, nurse practitioners, and practicing clinicians in the fields of high altitude biology, cardiovascular biology and medicine, tumor oncology, obstetrics, pediatrics, and orthodontics and for others who may be interested in hypoxia.

Molecular Basis of Cardiovascular Disease

Molecular Basis of Cardiovascular Disease
  • Author : Kenneth R. Chien,Eugene Braunwald
  • Publisher :Unknown
  • Release Date :1999
  • Total pages :637
  • ISBN : UOM:39015045649004
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Summary : Covering the molecular basis of heart disease, this text evaluates topics such as genetic mapping approaches in inherited cardiovascular disorders, and driving mechanisms in the transition from cardiac hypertrophy to heart failure.

Molecular Biology in Cellular Pathology

Molecular Biology in Cellular Pathology
  • Author : John Crocker,Paul G. Murray
  • Publisher :Unknown
  • Release Date :2003-09-12
  • Total pages :400
  • ISBN : 9780470864982
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Summary : The latest edition of this highly successful text, covers the major advances in the methods used in cellular and molecular pathology. In recent years, knowledge of the molecular organization of the cell has led to the development of powerful new techniques that bring greater accuracy and objectives to the diagnosis, prognosis and management of many diseases and to the study of pathological states. This book describes the latest molecular techniques available for the analysis of diseases. In particular it includes new techniques using fluorescent dyes, DNA microarrays, protein chemistry, and mass spectrometry. It also incorporates information from the Human Genome Project, and the new disciplines of genomics and proteomics, where relevant to pathology. Color plates are a new feature of this edition, illustrating the advances in fluorescence labeling of cells.