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Cellular Migration and Formation of Axons and Dendrites

Cellular Migration and Formation of Axons and Dendrites
  • Author : Bin Chen,Kenneth Y. Kwan
  • Publisher :Unknown
  • Release Date :2020-05-29
  • Total pages :618
  • ISBN : 9780128144084
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Summary : Cellular Migration and Formation of Neuronal Connections, Second Edition, the latest release in the Comprehensive Developmental Neuroscience series, presents the latest information on the genetic, molecular and cellular mechanisms of neural development. This book provides a much-needed update that underscores the latest research in this rapidly evolving field, with new section editors discussing the technological advances that are enabling the pursuit of new research on brain development. This volume focuses on the formation of axons and dendrites and cellular migration. Features leading experts in various subfields as section editors and article authors Presents articles that have been peer reviewed to ensure accuracy, thoroughness and scholarship Includes coverage of mechanisms which regulate the formation of axons and dendrites and cellular migration Covers neural activity, from cell-intrinsic maturation, to early correlated patterns of activity

Cellular Migration and Formation of Neuronal Connections

Cellular Migration and Formation of Neuronal Connections
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2013-05-06
  • Total pages :1080
  • ISBN : 9780123973474
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Summary : The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 2 offers 56 high level articles devoted mainly to Formation of Axons and Dendrites, Migration, Synaptogenesis, Developmental Sequences in the Maturation of Intrinsic and Synapse Driven Patterns. Series offers 144 articles for 2904 full color pages addressing ways in which the nervous system and its components develop Features leading experts in various subfields as Section Editors and article Authors All articles peer reviewed by Section Editors to ensure accuracy, thoroughness, and scholarship Volume 2 sections include coverage of mechanisms which regulate: the formation of axons and dendrites, cell migration, synapse formation and maintenance during development, and neural activity, from cell-intrinsic maturation to early correlated patterns of activity.

Neuronal Polarity: Establishment and Maintenance

Neuronal Polarity: Establishment and Maintenance
  • Author : Froylan Calderon de Anda,Annette Gaertner
  • Publisher :Unknown
  • Release Date :2018-07-12
  • Total pages :229
  • ISBN : 9782889455171
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Summary : The term polarity in a biological context is used to describe an asymmetry in morphology and distribution of molecules. In neurons, their complex shape with typically one axon and several dendrites reflects this asymmetry. Although neurons assume many different shapes and sizes they always maintain these two domains, which are essential for neuronal function. In the most simple view, neurons use their axon to transmit signals over long distances due to its capacity to extend to enormous lengths. Dendrites, on the other hand, are shorter and receive and integrate signals from different locations. The selection of the site where the axon and dendrites initially emerge during embryonic development is a tightly regulated event, eventually important for the correct formation of neuronal circuits, and disturbances of these processes can have pathological consequences due to circuit malformation. An important question is which mechanisms neurons utilize to specify the sites where axonal and dendrite outgrowth occurs and how their identities are maintained during and after development. The formation of these functionally diverse domains is the result of polarized differences of membrane and protein delivery, mitochondria transport, actin dynamics and microtubule stability. However how and in which temporal order all those events which coordinate the selection and maintenance of axons and dendrites is still under investigation. This selection of articles shall highlight new findings, which help to unravel all molecular and cellular events important for neuronal polarity establishment and maintenance.

Discovering the Brain

Discovering the Brain
  • Author : National Academy of Sciences,Institute of Medicine,Sandra Ackerman
  • Publisher :Unknown
  • Release Date :1992-01-01
  • Total pages :194
  • ISBN : 9780309045292
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Summary : The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brain--an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attention--and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniques--what various technologies can and cannot tell us--and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakers--and many scientists as well--with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."

From Neurons to Neighborhoods

From Neurons to Neighborhoods
  • Author : Division of Behavioral and Social Sciences and Education,Institute of Medicine,Board on Children, Youth, and Families,Committee on Integrating the Science of Early Childhood Development
  • Publisher :Unknown
  • Release Date :2000-11-13
  • Total pages :612
  • ISBN : 9780309069885
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Summary : How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the first months and years-have reached the popular media. How can we use our burgeoning knowledge to assure the well-being of all young children, for their own sake as well as for the sake of our nation? Drawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and other issues. The committee issues a series of challenges to decision makers regarding the quality of child care, issues of racial and ethnic diversity, the integration of children's cognitive and emotional development, and more. Authoritative yet accessible, From Neurons to Neighborhoods presents the evidence about "brain wiring" and how kids learn to speak, think, and regulate their behavior. It examines the effect of the climate-family, child care, community-within which the child grows.

Cyclin Dependent Kinase 5 (Cdk5)

Cyclin Dependent Kinase 5 (Cdk5)
  • Author : Nancy Y. Ip,Li-Huei Tsai
  • Publisher :Unknown
  • Release Date :2009-02-28
  • Total pages :313
  • ISBN : 0387788875
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Summary : Cyclin Dependent Kinase 5 provides a comprehensive and up-to-date collection of reviews on the discovery, signaling mechanisms and functions of Cdk5, as well as the potential implication of Cdk5 in the treatment of neurodegenerative diseases. Since the identification of this unique member of the Cdk family, Cdk5 has emerged as one of the most important signal transduction mediators in the development, maintenance and fine-tuning of neuronal functions and networking. Further studies have revealed that Cdk5 is also associated with the regulation of neuronal survival during both developmental stages and in neurodegenerative diseases. These observations indicate that precise control of Cdk5 is essential for the regulation of neuronal survival. The pivotal role Cdk5 appears to play in both the regulation of neuronal survival and synaptic functions thus raises the interesting possibility that Cdk5 inhibitors may serve as therapeutic treatment for a number of neurodegenerative diseases.

Building Brains

Building Brains
  • Author : David Price,Andrew P. Jarman,John O. Mason,Peter C. Kind
  • Publisher :Unknown
  • Release Date :2011-04-04
  • Total pages :352
  • ISBN : 9780470979884
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Summary :

Molecular Biology of the Cell

Molecular Biology of the Cell
  • Author : Bruce Alberts
  • Publisher :Unknown
  • Release Date :2004
  • Total pages :229
  • ISBN : 0815332181
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Summary :

Textbook of Neural Repair and Rehabilitation

Textbook of Neural Repair and Rehabilitation
  • Author : Michael Selzer,Stephanie Clarke,Leonardo Cohen,Gert Kwakkel,Robert Miller
  • Publisher :Unknown
  • Release Date :2014-04-24
  • Total pages :688
  • ISBN : 9781107011670
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Summary : Volume 1 of the Textbook of Neural Repair and Rehabilitation covers the basic sciences relevant to recovery of function following injury to the nervous system.

Fundamental Neuroscience

Fundamental Neuroscience
  • Author : Larry Squire,Darwin Berg,Floyd E. Bloom,Sascha du Lac,Anirvan Ghosh,Larry R. Squire,Nicholas C. Spitzer,Susan K. McConnell,James L. Roberts,Michael J. Zigmond
  • Publisher :Unknown
  • Release Date :2002-11-19
  • Total pages :1426
  • ISBN : 9780080521800
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Summary : With over 300 training programs in neuroscience currently in existence, demand is great for a comprehensive textbook that both introduces graduate students to the full range of neuroscience, from molecular biology to clinical science, but also assists instructors in offering an in-depth course in neuroscience to advanced undergraduates. The second edition of Fundamental Neuroscience accomplishes all this and more. The thoroughly revised text features over 25% new material including completely new chapters, illustrations, and a CD-ROM containing all the figures from the text. More concise and manageable than the previous edition, this book has been retooled to better serve its audience in the neuroscience and medical communities. Key Features * Logically organized into 7 sections, with uniform editing of the content for a "one-voice" feel throughout all 54 chapters * Includes numerous text boxes with concise, detailed descriptions of specific experiments, disorders, methodological approaches, and concepts * Well-illustrated with over 850 full color figures, also included on the accompanying CD-ROM

Synapse Development and Maturation

Synapse Development and Maturation
  • Author : Pasko Rakic,John Rubenstein,Bin Chen,Kenneth Y. Kwan
  • Publisher :Unknown
  • Release Date :2020-05-29
  • Total pages :558
  • ISBN : 9780128236734
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Summary : Synapse Development and Maturation, the latest release in the Comprehensive Developmental Neuroscience series, presents the latest information on the genetic, molecular and cellular mechanisms of neural development. The book provides a much-needed update that underscores the latest research in this rapidly evolving field, with new section editors discussing the technological advances that are enabling the pursuit of new research on brain development. This volume focuses on the synaptogenesis and developmental sequences in the maturation of intrinsic and synapse-driven patterns. Features leading experts in various subfields as section editors and article authors Presents articles that have been peer reviewed to ensure accuracy, thoroughness and scholarship Includes coverage of mechanisms which regulate synapse formation and maintenance during development Covers neural activity, from cell-intrinsic maturation, to early correlated patterns of activity

Comprehensive Developmental Neuroscience: Cellular Migration and Formation of Neuronal Connections

Comprehensive Developmental Neuroscience: Cellular Migration and Formation of Neuronal Connections
  • Author : F. Polleux
  • Publisher :Unknown
  • Release Date :2013-05-06
  • Total pages :1080
  • ISBN : 9780128062548
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Summary :

Extracellular and Intracellular Signaling

Extracellular and Intracellular Signaling
  • Author : Keith Parker
  • Publisher :Unknown
  • Release Date :2011
  • Total pages :303
  • ISBN : 9781849731607
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Summary : Intracellular cell signaling is a well understood process. However, extracellular signals such as hormones, adipokines, cytokines and neurotransmitters are just as important but have been largely ignored in other works. They are causative agents for diseases including hypertension, diabetes, heart disease, and arthritis so offer new, and often more approachable, targets for drug design. Aimed at medical professionals and pharmaceutical specialists, this book integrates extracellular and intracellular signalling processes and offers a fresh perspective on new drug targets. Written by colleagues at the same institution, but with contributions from leading international authorities, it is the result of close cooperation between the authors of different chapters. Readers are introduced to a new approach to disease causation by adipokines and toxic lipids. Heart disease, migraines, stroke, Alzheimer's disease, diabetes, cancer, and arthritis are approached from the perspective of prevention and treatment by alteration of extracellular signalling. Evidence is presented that the avoidance of toxic lifestyles can reduce the incidence of such illnesses and new therapeutic targets involving adipokines, ceramide and endocannabinoids are discussed.

Comprehensive Developmental Neuroscience: Cellular Migration and Formation of Neuronal Connections

Comprehensive Developmental Neuroscience: Cellular Migration and Formation of Neuronal Connections
  • Author : K. Boekhoorn,C.C. Hoogenraad
  • Publisher :Unknown
  • Release Date :2013-05-06
  • Total pages :1080
  • ISBN : 9780128062968
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Summary :

Developmental Neurobiology

Developmental Neurobiology
  • Author : Mahendra S. Rao,Marcus Jacobson
  • Publisher :Unknown
  • Release Date :2006-04-04
  • Total pages :424
  • ISBN : 9780387281179
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Summary : This consistent and well-illustrated text is an up-to-date survey of cellular and molecular events contributing to the assembly of the vertebrate nervous system. Chapters include a mixture of historical content and descriptions from literature that best illustrate specific aspects of development.

Comprehensive Developmental Neuroscience: Cellular Migration and Formation of Neuronal Connections

Comprehensive Developmental Neuroscience: Cellular Migration and Formation of Neuronal Connections
  • Author : L. Ma,D.A. Gibson
  • Publisher :Unknown
  • Release Date :2013-05-06
  • Total pages :1080
  • ISBN : 9780128062562
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Summary :

Principles of Neurobiology

Principles of Neurobiology
  • Author : Liqun Luo
  • Publisher :Unknown
  • Release Date :2020-09-05
  • Total pages :734
  • ISBN : 9781000096804
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Summary : Principles of Neurobiology, Second Edition presents the major concepts of neuroscience with an emphasis on how we know what we know. The text is organized around a series of key experiments to illustrate how scientific progress is made and helps upper-level undergraduate and graduate students discover the relevant primary literature. Written by a single author in a clear and consistent writing style, each topic builds in complexity from electrophysiology to molecular genetics to systems level in a highly integrative approach. Students can fully engage with the content via thematically linked chapters and will be able to read the book in its entirety in a semester-long course. Principles of Neurobiology is accompanied by a rich package of online student and instructor resources including animations, figures in PowerPoint, and a Question Bank for adopting instructors.

Fundamental Neuroscience

Fundamental Neuroscience
  • Author : Larry Squire,Floyd E. Bloom,Nicholas C. Spitzer,Larry R. Squire,Darwin Berg,Sascha du Lac,Anirvan Ghosh
  • Publisher :Unknown
  • Release Date :2008-04-02
  • Total pages :1280
  • ISBN : 0080561020
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Summary : Fundamental Neuroscience, 3rd Edition introduces graduate and upper-level undergraduate students to the full range of contemporary neuroscience. Addressing instructor and student feedback on the previous edition, all of the chapters are rewritten to make this book more concise and student-friendly than ever before. Each chapter is once again heavily illustrated and provides clinical boxes describing experiments, disorders, and methodological approaches and concepts. Capturing the promise and excitement of this fast-moving field, Fundamental Neuroscience, 3rd Edition is the text that students will be able to reference throughout their neuroscience careers! New to this edition: 30% new material including new chapters on Dendritic Development and Spine Morphogenesis, Chemical Senses, Cerebellum, Eye Movements, Circadian Timing, Sleep and Dreaming, and Consciousness Additional text boxes describing key experiments, disorders, methods, and concepts Multiple model system coverage beyond rats, mice, and monkeys Extensively expanded index for easier referencing

Receptors in the Evolution and Development of the Brain

Receptors in the Evolution and Development of the Brain
  • Author : Richard E. Fine, MD
  • Publisher :Unknown
  • Release Date :2019-04-15
  • Total pages :300
  • ISBN : 9780128110126
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Summary : Receptors in the Evolution and Development of the Brain: Matter into Mind presents the key role of receptors and their cognate ligands in wiring the mammalian brain from an evolutionary developmental biology perspective. It examines receptor function in the evolution and development of the nervous system in the large vertebrate brain, and discusses rapid eye movement sleep and apoptosis as mechanisms to destroy miswired neurons. Possible links between trophic deficits and connectional diseases including Alzheimer's, Parkinson's, and ALS are also discussed. This book is extremely useful to those with an interest in the molecular and cellular neurosciences, including those in cognitive and clinical branches of this subject, and anyone interested in how the incredibly complex human brain can build itself. Provides an understanding of the key role receptors play in brain development and the selection process necessary to construct a large brain Traces the evolution of receptors from the most primitive organisms to humans Emphasizes the roles that REM sleep and apoptosis play in this selection via trophic factors and receptors Describes the role that trophic factor-receptor interactions play throughout life and how trophic deficits can lead to connectional diseases, including Alzheimer's, Parkinson's and ALS Provides a potential mechanism whereby neuronal stem cells can cure these diseases

Cellular and Molecular Neurophysiology

Cellular and Molecular Neurophysiology
  • Author : Constance Hammond
  • Publisher :Unknown
  • Release Date :2014-12-30
  • Total pages :444
  • ISBN : 9780123973221
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Summary : Cellular and Molecular Neurophysiology, Fourth Edition, is the only up-to-date textbook on the market that focuses on the molecular and cellular physiology of neurons and synapses. Hypothesis-driven rather than a dry presentation of the facts, the book promotes a real understanding of the function of nerve cells that is useful for practicing neurophysiologists and students in a graduate-level course on the topic alike. This new edition explains the molecular properties and functions of excitable cells in detail and teaches students how to construct and conduct intelligent research experiments. The content is firmly based on numerous experiments performed by top experts in the field This book will be a useful resource for neurophysiologists, neurobiologists, neurologists, and students taking graduate-level courses on neurophysiology. 70% new or updated material in full color throughout, with more than 350 carefully selected and constructed illustrations Fifteen appendices describing neurobiological techniques are interspersed in the text

Neurons

Neurons
  • Author : Gonzalo Emiliano Aranda Abreu,María Elena Hernández Aguilar
  • Publisher :Unknown
  • Release Date :2019-02-20
  • Total pages :128
  • ISBN : 9781789851236
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Summary : The brain is the most complex structure that exists in the universe, consisting of neurons whose function is to receive information through dendrites and transmit information through the axon. In neurosciences one of the main problems that exists are neurodegenerative diseases for which until now there has been no cure. This book is mainly focused on updating the information on the signaling process carried out in the development of axons. Topics such as axon guidance and its interaction with the extracellular matrix are discussed. Other important topics are semaphorins and their relationship with neurodegenerative diseases, and the neurobiology of the gap junction in the dorsal root ganglion. Finally, the topic of bioelectrical interfaces destined to regenerate damaged nerves is covered. The information in this book will be very important both for researchers who work with these issues and doctoral students who are involved in neuroscience.