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Diamond-Based Materials for Biomedical Applications

Diamond-Based Materials for Biomedical Applications
  • Author : Roger Narayan
  • Publisher :Unknown
  • Release Date :2013-03-19
  • Total pages :296
  • ISBN : 9780857093516
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Summary : Carbon is light-weight, strong, conductive and able to mimic natural materials within the body, making it ideal for many uses within biomedicine. Consequently a great deal of research and funding is being put into this interesting material with a view to increasing the variety of medical applications for which it is suitable. Diamond-based materials for biomedical applications presents readers with the fundamental principles and novel applications of this versatile material. Part one provides a clear introduction to diamond based materials for medical applications. Functionalization of diamond particles and surfaces is discussed, followed by biotribology and biological behaviour of nanocrystalline diamond coatings, and blood compatibility of diamond-like carbon coatings. Part two then goes on to review biomedical applications of diamond based materials, beginning with nanostructured diamond coatings for orthopaedic applications. Topics explored include ultrananocrystalline diamond for neural and ophthalmological applications, nanodiamonds for drug delivery systems, and diamond nucleation and seeding techniques for tissue regeneration. Finally, the book concludes with a discussion of diamond materials for microfluidic devices. With its distinguished editors and international team of expert contributors, Diamond-based materials for biomedical applications is an authoritative guide for all materials scientists, researchers, medical practitioners and academics investigating the properties and uses of diamond based materials in the biomedical environment. Presents the fundamental principles and novel applications of this versatile material Discusses the functionalization of diamond particles and surfaces, biotribology and biological behaviour of nanocrystalinediamond coatings and blood compatibility of diamond-like carbon coatings Reviews nanostructured diamond coatings for orthopaedic coatings

Diamond-based materials for biomedical applications

Diamond-based materials for biomedical applications
  • Author : S. Szunerits,R. Boukherroub
  • Publisher :Unknown
  • Release Date :2013-03-19
  • Total pages :296
  • ISBN : 9780128087992
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Summary : Recent advances made in the controlled deposition of diamond thin films with varying morphologies have pushed researchers to consider diamond as an alternative carbon-based material. Surface functionalization is believed to be an effective approach to tune the physical, chemical and electrochemical properties of diamond. Understanding and controlling the functionalization process of diamond surfaces thus holds considerable promise for both fundamental and applied research aspects. This chapter summarizes the state of the art of chemical, photochemical and electrochemical strategies for the grafting of different organic moieties onto diamond.

Diamond-based materials for biomedical applications

Diamond-based materials for biomedical applications
  • Author : A. Karczemska
  • Publisher :Unknown
  • Release Date :2013-03-19
  • Total pages :296
  • ISBN : 9780128088074
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Summary : This chapter discusses the possibilities and advantages offered by the use of diamond materials in the fabrication of microfluidic devices. The correct choice of material with optimal properties is crucial in the design of modern microfluidic devices. The different applications of diamond materials in this field are reviewed, along with a discussion of recent development and future trends.

Diamond-based materials for biomedical applications

Diamond-based materials for biomedical applications
  • Author : M. Fedel
  • Publisher :Unknown
  • Release Date :2013-03-19
  • Total pages :296
  • ISBN : 9780128088012
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Summary : Diamond-like carbon (DLC) films offer numerous functional characteristics that make them particularly attractive as potential wear resistant coatings for biomedical applications. This chapter first discusses the blood compatibility of various forms of plain and doped DLCs, and evaluates possible correlations with film structure and surface properties. The chapter then considers the application of DLC coatings to different typologies of implants and medical devices, with special regard to cardiovascular prostheses.

Diamond-based materials for biomedical applications

Diamond-based materials for biomedical applications
  • Author : Y-C. Chen,D-C. Lee,N-H. Tai,I-M. Chiu
  • Publisher :Unknown
  • Release Date :2013-03-19
  • Total pages :296
  • ISBN : 9780128088043
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Summary : Diamond films have been considered as ideal candidates for protective coatings on bioimplants, as bioimplants themselves or as a guide for neural differentiation, because of their excellent mechanical properties, functional amenability, biocompatibility, and unique nanostructures. We separate nanocrystalline diamond films into two categories based on growth chemistries, nanostructure, and properties: nanocrystalline diamond (NCD) and ultrananocrystalline diamond (UNCD). UNCD is suitable for application as a hermetic coating for protection of implantable artificial retina medical devices, and also contributes to improvement of neural stem cell (NSC)-based cell transplantation, tissue engineering for neural tissue repair and regeneration and study of neural cell differentiation.

Diamond-based materials for biomedical applications

Diamond-based materials for biomedical applications
  • Author : A.E. Mengesha,B-B.C. Youan
  • Publisher :Unknown
  • Release Date :2013-03-19
  • Total pages :296
  • ISBN : 9780128088050
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Summary : Nanodiamonds offer a potential novel template for drug delivery and targeting, because of their small primary particle size, purity, excellent properties, facile surface functionalization, high biocompatibility, and inexpensive large-scale synthesis. However, nanodiamond properties such as aggregation state, surface chemistry, and presence of impurities, as well as the localization and accumulation behavior at the organism level, must be controlled to maintain safety and retain efficacy of conjugated therapeutic agents. A clinically applicable approach requires investigation of biocompatibility, biodistribution, and biological fate of the nanodiamond as well as its conjugates.

Diamond-based materials for biomedical applications

Diamond-based materials for biomedical applications
  • Author : A. Kromka,O. Babchenko,S. Potocky,B. Rezek,A. Sveshnikov,P. Demo,T. Izak,M. Varga
  • Publisher :Unknown
  • Release Date :2013-03-19
  • Total pages :296
  • ISBN : 9780128088067
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Summary : The growth of nanocrystalline diamond (NCD) thin films has become routine in labs and companies globally. This has been enabled by the fast progress of diamond nucleation and seeding in science and technology during the past decade, as a result of chemical vapour deposition (CVD) of NCD films requiring that a non-diamond substrate is treated by nucleation or seeding process prior to diamond growth. However, growth of ultrathin continuous NCD films (thickness

Diamond-based materials for biomedical applications

Diamond-based materials for biomedical applications
  • Author : S.A. Catledge,V. Thomas,Y.K. Vohra
  • Publisher :Unknown
  • Release Date :2013-03-19
  • Total pages :296
  • ISBN : 9780128088029
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Summary : With increasing numbers of orthopaedic devices being implanted, greater emphasis is being placed on ceramic coating technology to reduce friction and wear in mating total joint replacement components, in order to improve implant function and increase device lifespan. In this chapter, we consider ultra-hard carbon coatings, with emphasis on nanostructured diamond, as alternative bearing surfaces for metallic components. Such coatings have great potential for use in biomedical implants as a result of their extreme hardness, wear resistance, low friction and biocompatibility. These ultra-hard carbon coatings can be deposited by several techniques resulting in a wide variety of structures and properties.

Diamond-based materials for biomedical applications

Diamond-based materials for biomedical applications
  • Author : M. Amaral
  • Publisher :Unknown
  • Release Date :2013-03-19
  • Total pages :296
  • ISBN : 9780128088005
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Summary : This chapter discusses the application of nanocrystalline diamond (NCD) films as protective coatings for joint replacement. The chapter includes an overview of chemical vapour deposition (CVD) diamond and discusses the influence of hot-filament chemical vapour deposition (HFCVD) parameters on the deposition of NCD on silicon nitride (Si3N4) ceramics. The chapter then presents biotribological studies and in vitro cell cultures of the deposited NCD coatings.

Diamond-based materials for biomedical applications

Diamond-based materials for biomedical applications
  • Author : O. Auciello,P. Gurman,A. Berra,M. Saravia,R. Zysler
  • Publisher :Unknown
  • Release Date :2013-03-19
  • Total pages :296
  • ISBN : 9780128088036
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Summary : This chapter discusses the integration of physiology, new biomaterials and micro and nanofabrication technologies, which enable the development of new devices implantable in the human eye for diagnosis, monitoring, and/or therapeutic treatment of vision. The chapter focuses on the science and technology of biomaterials for three main applications: to restore sight to people blinded by genetically induced degeneration of retina photoreceptors; for draining aqueous humour from the eyes of people with glaucoma condition; and a novel method for retina detachment therapy.

Switchable and Responsive Surfaces and Materials for Biomedical Applications

Switchable and Responsive Surfaces and Materials for Biomedical Applications
  • Author : Johnathan Zhang
  • Publisher :Unknown
  • Release Date :2014-12-11
  • Total pages :324
  • ISBN : 9780857097170
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Summary : Surface modification of biomaterials can ultimately determine whether a material is accepted or rejected from the human body, and a responsive surface can further make the material "smart" and "intelligent". Switchable and Responsive Surfaces and Materials for Biomedical Applications outlines synthetic and biological materials that are responsive under different stimuli, their surface design and modification techniques, and applicability in regenerative medicine/tissue engineering, drug delivery, medical devices, and biomedical diagnostics. Part one provides a detailed overview of switchable and responsive materials and surfaces, exploring thermo-responsive polymers, environmentally responsive polyelectrolytes and zwitterionic polymers, as well as peptide-based and photonic sensitive switchable materials. Further chapters include a detailed overview of the preparation and analysis of switchable polymer brushes and copolymers for biomedical application. Part two explores the biological interactions and biomedical applications of switchable surfaces, where expert analysis is provided on the interaction of switchable surfaces with proteins and cells. The interaction of stimuli-sensitive polymers for tissue engineering and drug delivery with biosurfaces is critiqued, whilst the editor provides a skillful study into the application of responsive polymers in implantable medical devices and biosensors. A comprehensive overview of switchable and responsive materials and surfaces Includes in depth analysis of thermo-responsive polymers, photonic sensitive materials and peptide-based surfaces Detailed exploration of biological interactions of responsive and switchable surfaces, covering stimuli-sensitive polymers for drug delivery, surfaces with proteins/cells and application of polymers in medical devices

Biomaterials Science

Biomaterials Science
  • Author : William R Wagner,Shelly E. Sakiyama-Elbert,Guigen Zhang,Michael J. Yaszemski
  • Publisher :Unknown
  • Release Date :2020-05-23
  • Total pages :1616
  • ISBN : 9780128161388
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Summary : The revised edition of the renowned and bestselling title is the most comprehensive single text on all aspects of biomaterials science from principles to applications. Biomaterials Science, fourth edition, provides a balanced, insightful approach to both the learning of the science and technology of biomaterials and acts as the key reference for practitioners who are involved in the applications of materials in medicine. This new edition incorporates key updates to reflect the latest relevant research in the field, particularly in the applications section, which includes the latest in topics such as nanotechnology, robotic implantation, and biomaterials utilized in cancer research detection and therapy. Other additions include regenerative engineering, 3D printing, personalized medicine and organs on a chip. Translation from the lab to commercial products is emphasized with new content dedicated to medical device development, global issues related to translation, and issues of quality assurance and reimbursement. In response to customer feedback, the new edition also features consolidation of redundant material to ensure clarity and focus. Biomaterials Science, 4th edition is an important update to the best-selling text, vital to the biomaterials’ community. The most comprehensive coverage of principles and applications of all classes of biomaterials Edited and contributed by the best-known figures in the biomaterials field today; fully endorsed and supported by the Society for Biomaterials Fully revised and updated to address issues of translation, nanotechnology, additive manufacturing, organs on chip, precision medicine and much more. Online chapter exercises available for each chapter

Drug Delivery Nanosystems for Biomedical Applications

Drug Delivery Nanosystems for Biomedical Applications
  • Author : Chandra P Sharma
  • Publisher :Unknown
  • Release Date :2018-08-22
  • Total pages :451
  • ISBN : 9780323509237
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Summary : Drug Delivery Nanosystems for Biomedical Application reviews some of the most challenging nanosystems with different routes of delivery that are useful for specific drugs, from both efficacy and bioavailability points-of-view. The chapters explore how this area is developing, the present state of the field, and future developments, in particular, inorganic, metallic, polymeric, composite and lipid nanosystems and their possible evolution to clinical applications. The book is a valuable research reference for both researchers and industrial partners who are not only interested in learning about this area, but also want to gain insights on how to move towards translational research. Focuses on applications, including tissue engineering and regenerative technologies, showing how nanosystems are used in practice Explores how nanosystems are used to deliver a variety of drugs, including peptides, hormone growth factors and genes Assesses the safety and nanotoxicity aspects of drug delivery nanosystems

The Design, Synthetic Strategies and Biocompatibility of Polymer Scaffolds for Biomedical Application

The Design, Synthetic Strategies and Biocompatibility of Polymer Scaffolds for Biomedical Application
  • Author : Shunsheng Cao,Huijun Zhu
  • Publisher :Unknown
  • Release Date :2014-10-13
  • Total pages :357
  • ISBN : 9781608058761
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Summary : Frontiers in Biomaterials: The Design, Synthetic Strategies and Biocompatibility of Polymer Scaffolds for Biomedical Application, Volume 1 highlights the importance of biomaterials and their interaction with biological system. The need for the development of biomaterials as scaffold for tissue regeneration is driven by the increasing demands for materials that mimic functions of extracellular matrices of body tissues. This eBook covers the latest challenges on the biocompatibility of scaffold overtime after implantation and discusses the requirement of innovative technologies and strategies for the development of materials with long-lasting scaffold and biocompatibility functions. The contents of this eBook include chapters on cell-scaffold interactions in three dimensions, nanocrystalline diamond films for biomedical applications, bioceramics-design, synthesis and biological applications, polyester biomaterials for regenerative medicine, nanomaterials for skin regeneration and many more. This book is a valuable resource for MSc and PhD students , academic personnel and researchers seeking updated and critically important information on biomaterials and biomedical applications.

Hydroxyapatite (HAp) for Biomedical Applications

Hydroxyapatite (HAp) for Biomedical Applications
  • Author : Michael Mucalo
  • Publisher :Unknown
  • Release Date :2015-03-06
  • Total pages :404
  • ISBN : 9781782420415
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Summary : Hydroxyapatite in the form of hydroxycarbonate apatite is the principal mineral component of bone tissue in mammals. In Bioceramics, it is classed as a bioactive material, which means bone tissue grows directly on it when placed in apposition without intervening fibrous tissue. Hydroxyapatite is hence commonly used as bone grafts, fillers and as coatings for metal implants. This important book provides an overview of the most recent research and developments involving hydroxyapatite as a key material in medicine and its application. Reviews the important properties of hydroxyapatite as a biomaterial Considers a range of specific forms of the material and their advantages Reviews a range of specific medical applications for this important material

Shape Memory Polymers for Biomedical Applications

Shape Memory Polymers for Biomedical Applications
  • Author : L Yahia
  • Publisher :Unknown
  • Release Date :2015-03-19
  • Total pages :326
  • ISBN : 9780857097057
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Summary : Shape memory polymers (SMPs) are an emerging class of smart polymers which give scientists the ability to process the material into a permanent state and predefine a second temporary state which can be triggered by different stimuli. The changing chemistries of SMPs allows scientists to tailor important properties such as strength, stiffness, elasticity and expansion rate. Consequently SMPs are being increasingly used and developed for minimally invasive applications where the material can expand and develop post insertion. This book will provide readers with a comprehensive review of shape memory polymer technologies. Part 1 will discuss the fundamentals and mechanical aspects of SMPs. Chapters in part 2 will look at the range of technologies and materials available for scientific manipulation whilst the final set of chapters will review applications. Reviews the fundamentals of shape memory polymers with chapters focussing on the basic principles of the materials Comprehensive coverage of design and mechanical aspects of SMPs Expert analysis of the range of technologies and materials available for scientific manipulation

Bioresorbable Polymers for Biomedical Applications

Bioresorbable Polymers for Biomedical Applications
  • Author : Giuseppe Perale,Jöns Hilborn
  • Publisher :Unknown
  • Release Date :2016-08-24
  • Total pages :628
  • ISBN : 9780081002667
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Summary : Bioresorbable Polymers for Biomedical Applications: From Fundamentals to Translational Medicine provides readers with an overview of bioresorbable polymeric materials in the biomedical field. A useful resource for materials scientists in industry and academia, offering information on the fundamentals and considerations, synthesis and processing, and the clinical and R and D applications of bioresorbable polymers for biomedical applications. Focuses on biomedical applications of bioresorbable polymers Features a comprehensive range of topics including fundamentals, synthesis, processing, and applications Provides balanced coverage of the field with contributions from academia and industry Includes clinical and R and D applications of bioresorbable polymers for biomedical applications

Microfluidic Devices for Biomedical Applications

Microfluidic Devices for Biomedical Applications
  • Author : Xiujun James Li,Yu Zhou
  • Publisher :Unknown
  • Release Date :2013-10-31
  • Total pages :676
  • ISBN : 9780857097040
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Summary : Microfluidics or lab-on-a-chip (LOC) is an important technology suitable for numerous applications from drug delivery to tissue engineering. Microfluidic devices for biomedical applications discusses the fundamentals of microfluidics and explores in detail a wide range of medical applications. The first part of the book reviews the fundamentals of microfluidic technologies for biomedical applications with chapters focussing on the materials and methods for microfabrication, microfluidic actuation mechanisms and digital microfluidic technologies. Chapters in part two examine applications in drug discovery and controlled-delivery including micro needles. Part three considers applications of microfluidic devices in cellular analysis and manipulation, tissue engineering and their role in developing tissue scaffolds and stem cell engineering. The final part of the book covers the applications of microfluidic devices in diagnostic sensing, including genetic analysis, low-cost bioassays, viral detection, and radio chemical synthesis. Microfluidic devices for biomedical applications is an essential reference for medical device manufacturers, scientists and researchers concerned with microfluidics in the field of biomedical applications and life-science industries. Discusses the fundamentals of microfluidics or lab-on-a-chip (LOC) and explores in detail a wide range of medical applications Considers materials and methods for microfabrication, microfluidic actuation mechanisms and digital microfluidic technologies Considers applications of microfluidic devices in cellular analysis and manipulation, tissue engineering and their role in developing tissue scaffolds and stem cell engineering

Semiconducting Silicon Nanowires for Biomedical Applications

Semiconducting Silicon Nanowires for Biomedical Applications
  • Author : J.L. Coffer
  • Publisher :Unknown
  • Release Date :2014-02-17
  • Total pages :296
  • ISBN : 9780857097712
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Summary : Biomedical applications have benefited greatly from the increasing interest and research into semiconducting silicon nanowires. Semiconducting Silicon Nanowires for Biomedical Applications reviews the fabrication, properties, and applications of this emerging material. The book begins by reviewing the basics, as well as the growth, characterization, biocompatibility, and surface modification, of semiconducting silicon nanowires. It goes on to focus on silicon nanowires for tissue engineering and delivery applications, including cellular binding and internalization, orthopedic tissue scaffolds, mediated differentiation of stem cells, and silicon nanoneedles for drug delivery. Finally, it highlights the use of silicon nanowires for detection and sensing. These chapters explore the fabrication and use of semiconducting silicon nanowire arrays for high-throughput screening in the biosciences, neural cell pinning on surfaces, and probe-free platforms for biosensing. Semiconducting Silicon Nanowires for Biomedical Applications is a comprehensive resource for biomaterials scientists who are focused on biosensors, drug delivery, and tissue engineering, and researchers and developers in industry and academia who are concerned with nanoscale biomaterials, in particular electronically-responsive biomaterials. Reviews the growth, characterization, biocompatibility, and surface modification of semiconducting silicon nanowires Describes silicon nanowires for tissue engineering and delivery applications, including cellular binding and internalization, orthopedic tissue scaffolds, mediated differentiation of stem cells, and silicon nanoneedles for drug delivery Highlights the use of silicon nanowires for detection and sensing

Precious Metals for Biomedical Applications

Precious Metals for Biomedical Applications
  • Author : Niklaus Baltzer,Thierry Copponnex
  • Publisher :Unknown
  • Release Date :2014-05-07
  • Total pages :236
  • ISBN : 9780857099051
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Summary : Precious metals and semi-precious metals are used for an increasing number of medical applications due to the properties of these metals and their alloys. Precious Metals for Biomedical Applications reviews the properties of precious metals and their resulting applications in medicine. Part one outlines the fundamentals of precious metals for biomedical applications, discussing their useful properties, such as biocompatibility and corrosion resistance. Part two goes on to provide an overview of the applications of precious metals in biomedicine, including dental, therapeutic, tissue engineering, and bioimaging applications. It discusses the advantages of the structure and properties of precious metals for these applications. Precious Metals for Biomedical Applications is a key reference for material scientists and academics concerned with the properties and uses of these metals. Provides a useful review of this group of materials’ unique properties and applications Examines the fundamentals of precious metals for biomedical applications, before looking at a wide range of applications of precious metals in medicine

Surface Modification of Magnesium and its Alloys for Biomedical Applications

Surface Modification of Magnesium and its Alloys for Biomedical Applications
  • Author : T.S.N. Sankara Narayanan,Il-Song Park,Min-Ho Lee
  • Publisher :Unknown
  • Release Date :2015-01-30
  • Total pages :460
  • ISBN : 9781782420835
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Summary : The development of biodegradable implants which can remain in the human body to fix a problem and subsequently dissolve, or be absorbed, consumed or excreted, without warranting a secondary surgery, is very appealing to scientists. Due to their excellent biocompatibility and biodegradability, magnesium implants provide a viable option many problems associated with permanent metallic implants such as, restenosis, thrombosis, permanent physical irritation, and inability to adapt to growth and changes in human body. Volume 2 of this important new book explores practical issues of magnesium and magnesium alloys, physical and mechanical modification and coatings to enhance this material for biomedical applications. Includes expert analysis on chemical solution deposition of hydroxyapatite (HAp) and octacalcium (OCP) phosphate coatings for magnesium Comprehensive coverage of biomimetic modifications, surface functionalization of biomolecules, natural, conducting and biodegradable polymeric coatings Lucid dissection of chemical, physical, mechanical and electromechanical modifications of magnesium and its alloys for biomedical applications