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Dual Antiplatelet Therapy for Coronary and Peripheral Arterial Disease

Dual Antiplatelet Therapy for Coronary and Peripheral Arterial Disease
  • Author : Sorin Brener
  • Publisher :Unknown
  • Release Date :2021-01-09
  • Total pages :220
  • ISBN : 9780128205372
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Summary : Dual Antiplatelet Therapy for Coronary and Peripheral Arterial Disease is a complete reference containing updated information on the advantages and disadvantages of dual antiplatelet therapy, its duration, composition and anticipated changes. The basis for DAPT in arterial disease is discussed, allowing readers to understand platelet physiology and its relevance to ischemic events. Data on shorter than usual duration of DAPT, and on extended therapy beyond the recommendation of current guidelines is presented in great detail, summarizing a large body of evidence into concrete, relevant recommendation that is readily adaptable by practicing clinicians. A clinically relevant and updated compendium of data pertaining to this field is also presented, as well as the anticipated trends and innovations likely to occur in the next 3-5 years. Summarizes a large body of evidence into concrete, relevant recommendations that is readily adapted by practicing clinicians Explores the current status of DAPT, controversial topics, and future developments and trends in this field Edited and contributed by renowned cardiologists in the field

Antiplatelet Therapy in Cardiovascular Disease

Antiplatelet Therapy in Cardiovascular Disease
  • Author : Ron Waksman,Paul A. Gurbel,Michael A. Gaglia, Jr.
  • Publisher :Unknown
  • Release Date :2014-03-24
  • Total pages :352
  • ISBN : 9781118494028
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Summary : Edited by one of the world's leading interventional cardiologistsand educators, this new book is created with an eye on giving thereader a solid, practical and clinically-focused understanding ofthis important class of drugs, from basic science to a clear-headeddiscussion of complex topics such as combination therapies,drug-drug interactions, and platelet resistance. This important new book: Begins with a concise but thorough discussion of plateletbiology and pathophysiology so that readers understand how thesetherapies work and why they can also produce such a varied range ofcomplications, from minor gastrointestinal upset, to potentiallylife-threatening conditions such as neutropenia, a criticalshortage of white blood cells. Thoroughly covers platelet function testing, including new,novel techniques. Clarifies current best-practices regarding the use ofantiplatelet agents in both chronic and acute cardiovasculardisease Reviews of all types of antiplatelet agents – fromaspirin to recently approved drugs – including indications,clinical outcomes, and side effects/complications Written by an international who's-who of experts in the field,Antiplatelet Therapy also includes an entire section covering theuse of antiplatelet drugs in PCIs, including percutaneous valverepair, which makes this text particularly essential toInterventional Cardiologists.

The Esc Textbook of Cardiovascular Medicine

The Esc Textbook of Cardiovascular Medicine
  • Author : A. John Camm,Professor of Clinical Cardiology A John Camm,Director of Research Education & Development and Consultant of Cardiology Thomas F Luscher,Thomas F. Luscher,Gerald Maurer,Professor of Cardiology Patrick W Serruys, MD, PhD
  • Publisher :Unknown
  • Release Date :2018-11-25
  • Total pages :2384
  • ISBN : 0198784902
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Summary : This new third edition of The ESC Textbook of Cardiovascular Medicine is a ground breaking initiative from the European Society of Cardiology that is transforming reference publishing in cardiovascular medicine in order to better serve the changing needs of the global cardiology community. Providing the evidence-base behind clinical practice guidelines, with in-depth peer-reviewed articles and broad coverage of this fast-moving field, both the print and digital publication are invaluable resources for cardiologists across the world. Overseen by Professors A. John Camm, Thomas F. Lüscher, Patrick W. Serruys, and Gerald Maurer, supported by an editorial board of subject experts, and more than 900 of the world's leading specialists from research and the clinic contributing, this dynamic encyclopaedic resource covers more than 63 disciplines within cardiology. Split into six key parts; Introduction to the cardiovascular system; Investigations; Heart diseases; Vascular disease; Special populations, and Other aspects of cardiology, providing readers with a trustworthy insight into all aspects of cardiovascular medicine. To respond nimbly to the rapid evolution of the field the digital publication, ESC CardioMed, is continuously updated by the author teams. With expert editors and authors, and stringent peer-review, the publication combines the discoverability of digital with the highest standards of academic publishing. Highly illustrated with embedded multi-media features, along with cross-referenced links to ESC Clinical Practice Guidelines, related content and primary research data in European Heart Journal, as well as all other major journals in the field, ESC CardioMed provides users with the most dynamic and forward thinking digital resource at the heart of cardiology. As a consistently evolving knowledge base, the ESC Textbook of Cardiovascular Medicine 3e together with the online counterpart ESC CardioMed, equips all those, from trainees and consultants, to device specialists and allied healthcare professionals with a powerful, multifaceted resource covering all aspects of cardiovascular medicine.

Clopidogrel and the Newer P2y12 Antiplatelet Agents

Clopidogrel and the Newer P2y12 Antiplatelet Agents
  • Author : Michael P. Savage,David L. Fischman,Mamas A. Mamas
  • Publisher :Unknown
  • Release Date :2019
  • Total pages :308
  • ISBN : 153614973X
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Summary : Cardiovascular disease remains the leading cause of death in the developed world. By preventing thromboembolic events such as heart attacks and strokes, antiplatelet drugs have become a cornerstone in the treatment of cardiovascular disease. Clopidogrel is a member of the thienopyridine family which inhibit ADP-induced platelet activation by irreversibly binding to the P2Y12 receptor. Clopidogrel is one of the most commonly used medications with over 9 million prescriptions written annually. It is utilized in the treatment of a wide variety of cardiovascular disorders including acute coronary syndromes (ACS), percutaneous coronary intervention (PCI) with stents, cerebrovascular disease, peripheral vascular disease, and structural heart interventions. Most often, clopidogrel is used in combination with low dose aspirin, providing dual antiplatelet therapy (DAPT). Newer, more potent P2Y12 inhibitors, prasugrel and ticagrelor, are now available as alternatives to clopidogrel. These newer agents have been shown to be more effective than clopidogrel in reducing ischemic events in patients with ACS. Recently a novel intravenous P2Y12 inhibitor, cangrelor, has become available for use during PCI in patients who have not been pretreated with an oral P2Y12 inhibitor. This book examines virtually all aspects of P2Y12 inhibitors - pharmacology, clinical uses, randomized trial results, guideline recommendations, and adverse drug effects. Important fundamental issues are reviewed including comparative pharmacology of P2Y12 inhibitors, randomized trials of clopidogrel in patients with coronary artery disease, DAPT duration after PCI, and role of platelet function testing. The newer P2Y12 inhibitors (prasugrel, ticagrelor, and cangrelor) receive special focus. Use of antiplatelet therapy in specific patient populations is discussed including patients with coronary bypass graft surgery, peripheral vascular disease, cerebrovascular disease, and structural heart disease. Management of antiplatelet therapy in patients who require anticoagulation is a particularly challenging clinical setting and is the topic of a featured review. Finally, adverse drug effects and reactions are examined in a section highlighting clopidogrel resistance, clopidogrel hypersensitivity, and bleeding complications. This book is designed to provide a comprehensive review of clopidogrel and the newer P2Y12 inhibitors. Towards that end, the authors have enlisted an internationally renowned group of experts as contributors. It is intended to be a resource for clinicians, scientists, pharmacologists, and all healthcare professionals involved in the management of cardiovascular disease.

Drug-Coated Balloons

Drug-Coated Balloons
  • Author : Bernardo Cortese
  • Publisher :Unknown
  • Release Date :2019-06-19
  • Total pages :234
  • ISBN : 9783319926001
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Summary : This book provides a comprehensive, up-to-date summary of drug-coated balloon (DCB) technology and the role of DCBs in the treatment of coronary and peripheral arterial disease. In addition to clear explanation of how DCBs works, readers will find an enlightening analysis of the mistakes and successes of the past decade and the emergence of the latest delivery systems, which combine a more deliverable device with much improved drug delivery to the vessel wall. The full range of current applications of DCBs are reviewed in detail, drawing on the latest scientific evidence. Due attention is paid to newer devices, with provision of technical insights and documentation of the available clinical data. Ongoing research projects, remaining technical challenges, likely future directions, and reimbursement issues are also carefully considered. This book will be a useful tool for any interventional cardiologist, interventional radiologist, or vascular surgeon who wishes to acquire a deep knowledge of this technology and its application in both coronary and peripheral interventions.

State of the Art Surgical Coronary Revascularization

State of the Art Surgical Coronary Revascularization
  • Author : David P. Taggart,John D. Puskas,Professor of Cardiovascular Surgery John D Puskas
  • Publisher :Unknown
  • Release Date :2021-02
  • Total pages :576
  • ISBN : 9780198758785
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Summary : This is the most authoritative textbook ever dedicated to the art and science of surgical coronary revascularization, with 71 chapters, organized in 9 sections, and written by over 100 recognized world experts. It covers every aspect of the surgical management of coronary artery pathology and ischaemic heart disease.

Critical Leg Ischaemia

Critical Leg Ischaemia
  • Author : John A. Dormandy,Günter Stock
  • Publisher :Unknown
  • Release Date :2012-12-06
  • Total pages :172
  • ISBN : 9783642756252
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Summary : Jean Natali The pathophysiology and management of chronic critical limb -ischaemia (CLI) has always been a problematic area, at least partly because it involves doc tors from a wide range of the traditional medical specialities including vascular surgery, angiology, diabetology, haematology and radiology. The treatment of these patients also varies largely with local circumstances and national traditions. CLI therefore seemed a particularly appropriate subject for a new type of European consensus approach. In 1988 a series of small workshops were held by the European Working Group on Critical Limb Ischaemia to discuss the definition, pathophysiology, in vestigation and management of this condition. The process culminated in a meet ing in Berlin in March, 1989 where 120 specialists from sixteen European countries, representing the basic sciences as well as a spectrum of clinical dis ciplines, met to evolve a Consensus Document on the subject with specific recom mendations. The Document, which is reproduced in the first section of this book, does not of course necessarily represent the unanimous view of all those who participated in its compilation; however it is agreed that it does represent a con sensus or majority view. It was also noted that the comments and recommenda tions in the document should be taken as a whole, and are not intended to dictate the only correct approach to individual treatment.

Platelets in Thrombotic and Non-Thrombotic Disorders

Platelets in Thrombotic and Non-Thrombotic Disorders
  • Author : Paolo Gresele,Neal S. Kleiman,José A. Lopez,Clive P. Page
  • Publisher :Unknown
  • Release Date :2017-03-08
  • Total pages :1445
  • ISBN : 9783319474625
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Summary : This book reviews current science and applications in fields including thrombosis and hemostasis, signal transduction, and non-thrombotic conditions such as inflammation, allergy and tumor metastasis. It is a detailed, up-to-date, highly referenced text for clinical scientists and physicians, including recent developments in this rapidly expanding field. More than a scientific resource, this is also an authoritative reference and guide to the diagnosis.

Cardiovascular Thrombus

Cardiovascular Thrombus
  • Author : On Topaz
  • Publisher :Unknown
  • Release Date :2018-08-18
  • Total pages :670
  • ISBN : 9780128126165
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Summary : Cardiovascular Thrombus: From Pathology and Clinical Presentations to Imaging, Pharmacotherapy and Interventions provides a comprehensive, up-to-date presentation of the research and clinical practices as related to the contemporary aspects of the diagnosis and management of cardiovascular thrombosis. The formation, identification and management of cardiovascular thrombus is of paramount importance for researchers and practicing physicians, yet it remains one of the most challenging diagnostic and clinical scenarios. This important reference connects between research, up-to-date clinical knowledge, and the technological tools available for diagnosis and management of thrombus in cardiovascular medicine. The book includes comprehensive descriptions and review of pathology, clinical presentations, diagnosis, pharmacotherapy, interventions and future trends. It is the perfect reference for basic science students and researchers in general and interventional cardiology, general and interventional radiology, vascular medicine specialists, and vascular, general and cardiac surgeons. Provides comprehensive presentation of the pathophysiology, clinical presentations and diagnosis of cardiovascular thrombosis Includes the most up-to-date information on the practical management of patients with thrombus related conditions Written by the leading experts in the field Describes the current and upcoming pharmacotherapy and technology available for thrombus research and treatment

The Durability of Vascular and Endovascular Surgery

The Durability of Vascular and Endovascular Surgery
  • Author : Roger Malcolm Greenhalgh
  • Publisher :Unknown
  • Release Date :1999
  • Total pages :524
  • ISBN : UOM:39015042797913
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Summary : With an international range of contributors, this work discusses the new techniques of endovascular surgery in relation to established open surgical procedures.

Cardiovascular Outcomes of Treatments Available for Patients with Type 1 and 2 Diabetes, an Issue of Endocrinology and Metabolism Clinics of North America, E-Book

Cardiovascular Outcomes of Treatments Available for Patients with Type 1 and 2 Diabetes, an Issue of Endocrinology and Metabolism Clinics of North America, E-Book
  • Author : Guillermo E. Umpierrez
  • Publisher :Unknown
  • Release Date :2018-02-09
  • Total pages :229
  • ISBN : 9780323583985
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Summary : This issue of Endocrinology and Metabolism Clinics, edited by Dr. Guillermo E. Umpierrez, will focus on Cardiovascular Outcomes of Treatments available for Patients with Type 1 and 2 Diabetes. Topics include--but are not limited to--Diabetes and CAD and PVD; Prediabetes and CVD- DM prevention; Pathogenesis of atherosclerosis/CVD in diabetes Intensive Diabetes Treatment and CV Outcomes in T1D; Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes, Diabetes and Stroke; Cardiovascular outcome trials of glucose-lowering drugs or strategies in type 2 diabetes; Heart Failure in Diabetes Mellitus; Individualizing Glucose Lowering Therapy in the Patient with Diabetes and Heart Disease; Managing Dyslipidemia in Type 2 Diabetes; Blood pressure control and cardiovascular and renal outcomes; Hyperglycemia in acute coronary syndromes; Hospital Glucose Control; Managing Diabetes and cardiovascular risk in chronic kidney disease; and more.

Nash and Nafld, an Issue of Clinics in Liver Disease, E-Book

Nash and Nafld, an Issue of Clinics in Liver Disease, E-Book
  • Author : David Bernstein
  • Publisher :Unknown
  • Release Date :2017-11-19
  • Total pages :229
  • ISBN : 9780323569873
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Summary : Obesity has devastating effects on a patient's overall health, with specific negative effects on organ systems, long-term. The hepatologist must often manage diseases of the liver and pancreas as a result of obesity. This issue will provide a current update on the diagnosis, treatment, and management of NAFLD and NASH. Dr. Bernstein has assembled the top leaders in the field to provide timely clinical reviews. Articles are devoted to the following topics: Clinical and economic burden of NAFLD/NASH; NAFLD/NASH in children and its implications; Natural history of NAFLD/NASH; Diagnosis and evaluation of NAFLD/NASH; Radiological imaging in NAFLD/NASH; The use of liver biopsy in NAFLD: When to biopsy and in whom; Pathophysiology of NAFLD/NASH; Risk factors for the development of NAFLD/NASH including genetics; Role of intestinal microbes in NAFLD/NASH; NAFLD/NASH and the metabolic syndrome; NAFLD/NASH and lipid and insulin resistance; NAFLD/NASH and cardiac disease; Current treatment of NAFLD/NASH; Emerging treatment of NAFLD/NASH; NAFLD/NASH and HCC and NAFLD/NASH and liver transplantation. Readers will have a clear understanding of how to manage outcomes for these patients.

Peripheral and Cerebrovascular Intervention

Peripheral and Cerebrovascular Intervention
  • Author : Deepak L. Bhatt
  • Publisher :Unknown
  • Release Date :2011-11-20
  • Total pages :236
  • ISBN : 1603279652
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Summary : Peripheral and Cerebrovascular Intervention draws upon experts from diverse fields to provide readers with a comprehensive foundation for understanding and performing endovascular procedures—from the basic steps to the most current and advanced techniques. Individual chapters focus on primary intervention sites, including lower extremity, renal/mesenteric, subclavian/upper extremity, carotid/vertebral, intracranial and venous interventions. Additionally, chapters covering critical limb ischemia and abdominal and thoracic aortic aneurysms are included. By incorporating valuable clinical information, such as indications, contraindications, complications and discussions of surgical techniques and procedures, this book is a valuable resource for the busy practitioner and will be of interest to all interventional and general cardiologists, radiologists and neurologists; vascular surgeons; internists and residents and fellows.

The ESC Handbook on Cardiovascular Pharmacotherapy

The ESC Handbook on Cardiovascular Pharmacotherapy
  • Author : Juan Carlos Kaski,Keld Per Kjeldsen
  • Publisher :Unknown
  • Release Date :2019-05-23
  • Total pages :960
  • ISBN : 9780198759935
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Summary : The ESC Handbook on Cardiovascular Pharmacotherapy, based on the most recent guidelines in cardiovascular pharmacology, and containing a comprehensive A-Z formulary of common and less commonly used cardiac drugs and drug groups, provides practical and accessible guidance on all areas of drugprescribing.Previously published as Drugs in Cardiology, this new edition has been developed by the ESC Working Group on Cardiovascular Pharmacology. Pharmacology is an integral aspect in almost all disciplines within cardiology and all cardiologists use cardiovascular drugs.Completely updated and aligned with the ESC Clinical Practice Guidelines for prescribing, this handbook is essential reading for consultants, registrars in training, general practitioners, specialist cardiac nurses and cardiovascular pharmacologists.

Carotid Interventions

Carotid Interventions
  • Author : Peter Schneider,Todd Bohannon,Michael Silva
  • Publisher :Unknown
  • Release Date :2004-08-30
  • Total pages :322
  • ISBN : 9781000611380
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Summary : From patient selection and monitoring to follow-up care, Carotid Interventions is the first source to offer a practical how-to approach to carotid angioplasty and stenting-providing maneuvers and strategies for difficult situations, as well as step-by-step guidance on specific surgical procedures, equipment selection and instrumentation, protection

Peripheral Arterial Disease

Peripheral Arterial Disease
  • Author : Nishtha Sareen,Abhishek Ojha
  • Publisher :Unknown
  • Release Date :2018-10-17
  • Total pages :126
  • ISBN : 9781789842173
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Summary : "Peripheral Arterial Disease - A Practical Approach" is an honest effort to provide a clinically relevant approach to the management plan in patients presenting with peripheral vascular symptoms. We have summarized the most pertinent practical aspects of peripheral vascular disease, their clinical implications, diagnostic testing, therapeutic interventions and innovations. We hope this book serves as a reference for basic and advanced peripheral vascular care.

Antithrombotic Therapy

Antithrombotic Therapy
  • Author : Richard C. Becker,Dan J. Fintel,David Green
  • Publisher :Unknown
  • Release Date :2010-12-31
  • Total pages :464
  • ISBN : 9781932610635
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Summary : Care of patients with atherothrombosis involving the cardiovascular, pheripheral vascular, and cerebrovascular systems.

The Role of Antiplatelet Therapy in Patients with Peripheral Artery Disease and Lower Extremity Peripheral Artery Revascularization

The Role of Antiplatelet Therapy in Patients with Peripheral Artery Disease and Lower Extremity Peripheral Artery Revascularization
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2015
  • Total pages :229
  • ISBN : OCLC:1051777962
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Summary : Abstract Purpose of review Although antiplatelet agents are frequently prescribed to patients with lower extremity peripheral artery disease (PAD), there is an overall lack of consensus among published evidence and guidelines with respect to this practice. Recent findings Antiplatelet agents are prescribed to patients with PAD to reduce both cardiovascular and limb-based events during the follow-up period. A large evidence base supports the use of antiplatelet monotherapy with aspirin or clopidogrel in patients with symptomatic PAD or a history of peripheral artery revascularization. However, antiplatelet monotherapy has not proven beneficial in patients with asymptomatic PAD. Dual antiplatelet therapy has not demonstrated a clear benefit in reducing the risk of cardiovascular events in patients with symptomatic PAD. Its role in reducing the risk of adverse limb events following endovascular or surgical revascularization also remains unclear. Recently, the use of vorapaxar in addition to aspirin and/or clopidogrel has been associated with a significant reduction in the need for repeat revascularization procedures and hospitalization for limb ischemia in patients with established PAD. Summary Eligible patients with symptomatic PAD or with a history of peripheral artery revascularization should be prescribed antiplatelet monotherapy for secondary prevention of both cardiovascular and limb events, using aspirin, clopidogrel, and/or vorapaxar. Given the significant overlap of PAD and coronary artery disease, the evidence presented in this article may have important implications for management of patients with coronary artery disease.

Antiplatelet Agents

Antiplatelet Agents
  • Author : Paolo Gresele,Gustav V. R Born,Carlo Patrono,Clive P. Page
  • Publisher :Unknown
  • Release Date :2012-08-23
  • Total pages :616
  • ISBN : 9783642294235
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Summary : Antiplatelet therapy is the cornerstone of treatment of ischemic cardiovascular disease and over the last few years spectacular advancements in this field have been recorded. This is the first comprehensive handbook entirely dedicated to all the aspects of antiplatelet therapy. The book is divided into three main sections, pathophysiology, pharmacology and therapy, for a total of 23 chapters. A large group of leading experts from different European countries and from the USA, both from academia and industry, have contributed to the book. Besides a detailed overview on the pharmacology and clinical applications of all the currently used or of the novel antiplatelet agents, innovative approaches (e.g. intracellular signalling as an antiplatelet target, small RNAs as platelet therapeutics, etc.) or unconventional aspects (e.g. pharmacologic modulation of the inflammatory action of platelets are also treated. The book is oriented to both basic investigators and to clinicians involved with research on platelet inhibition or with the clinical use of antiplatelet therapies.

Intracranial Atherosclerosis: Pathophysiology, Diagnosis and Treatment

Intracranial Atherosclerosis: Pathophysiology, Diagnosis and Treatment
  • Author : J.S. Kim,L.R. Caplan,K.S. Wong
  • Publisher :Unknown
  • Release Date :2016-12-02
  • Total pages :226
  • ISBN : 9783318027594
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Summary : Intracranial atherosclerosis is a leading cause of stroke in Asians and Africans. As these ethnic groups account for more than 70% of the world’s population, it is in fact the major cause of ischemic stroke worldwide. This timely book provides readers with up-to-date knowledge of intracranial atherosclerosis, covering vascular anatomy, pathology, epidemiology, stroke mechanisms and syndromes, diagnostic methods as well as treatment strategies such as antithrombotics, angioplasty/stenting and surgery. Furthermore, nonatherosclerotic intracranial arterial diseases like Moyamoya disease, dissection, vasculitis and other miscellaneous disorders are extensively discussed. Experts from both East and West present the latest findings from cutting-edge research and discuss controversial topics from different yet balanced points of view, allowing readers to form their own unbiased opinion on these issues. With this approach, the book serves as a useful and stimulating guide on the diagnosis and management of intracranial atherosclerosis for neurologists, neurosurgeons, neuroradiologists and vascular interventionists.

Cardiovascular Intervention: A Companion to Braunwald’s Heart Disease E-Book

Cardiovascular Intervention: A Companion to Braunwald’s Heart Disease E-Book
  • Author : Deepak L. Bhatt
  • Publisher :Unknown
  • Release Date :2015-03-22
  • Total pages :544
  • ISBN : 9780323263610
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Summary : Introducing Cardiovascular Intervention, a comprehensive companion volume to Braunwald’s Heart Disease. This medical reference book contains focused chapters on how to utilize cutting-edge interventional technologies, with an emphasis on the latest protocols and standards of care. Cardiovascular Intervention also includes late-breaking clinical trials, "Hot off the Press" commentary, and Focused Reviews that are relevant to interventional cardiology. View immersive videos from an online library of procedural clips located on Expert Consult. Remain abreast of the newest interventional techniques, including next-generation stents, invasive lesion assessment, and methods to tackle complex anatomy. Provide optimal patient care with help from easy-to-access information on the latest diagnostic and treatment advances, discussions on percutaneous approaches to structural heart disease, and new developments in treating heart valve disease.