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Ecology and Evolution of Cancer

Ecology and Evolution of Cancer
  • Author : Beata Ujvari,Benjamin Roche,Frederic Thomas
  • Publisher :Unknown
  • Release Date :2017-02-08
  • Total pages :290
  • ISBN : 9780128043806
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Summary : Ecology and Evolution of Cancer is a timely work outlining ideas that not only represent a substantial and original contribution to the fields of evolution, ecology, and cancer, but also goes beyond by connecting the interfaces of these disciplines. This work engages the expertise of a multidisciplinary research team to collate and review the latest knowledge and developments in this exciting research field. The evolutionary perspective of cancer has gained significant international recognition and interest, which is fully understandable given that somatic cellular selection and evolution are elegant explanations for carcinogenesis. Cancer is now generally accepted to be an evolutionary and ecological process with complex interactions between tumor cells and their environment sharing many similarities with organismal evolution. As a critical contribution to this field of research the book is important and relevant for the applications of evolutionary biology to understand the origin of cancers, to control neoplastic progression, and to prevent therapeutic failures. Covers all aspects of the evolution of cancer, appealing to researchers seeking to understand its origins and effects of treatments on its progression, as well as to lecturers in evolutionary medicine Functions as both an introduction to cancer and evolution and a review of the current research on this burgeoning, exciting field, presented by an international group of leading editors and contributors Improves understanding of the origin and the evolution of cancer, aiding efforts to determine how this disease interferes with biotic interactions that govern ecosystems Highlights research that intends to apply evolutionary principles to help predict emergence and metastatic progression with the aim of improving therapies

The Cheating Cell

The Cheating Cell
  • Author : Athena Aktipis
  • Publisher :Unknown
  • Release Date :2020-03-24
  • Total pages :256
  • ISBN : 9780691163840
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Summary : A fundamental and groundbreaking reassessment of how we view and manage cancer When we think of the forces driving cancer, we don’t necessarily think of evolution. But evolution and cancer are closely linked, for the historical processes that created life also created cancer. The Cheating Cell delves into this extraordinary relationship, and shows that by understanding cancer’s evolutionary origins, researchers can come up with more effective, revolutionary treatments. Athena Aktipis goes back billions of years to explore when unicellular forms became multicellular organisms. Within these bodies of cooperating cells, cheating ones arose, overusing resources and replicating out of control, giving rise to cancer. Aktipis illustrates how evolution has paved the way for cancer’s ubiquity, and why it will exist as long as multicellular life does. Even so, she argues, this doesn’t mean we should give up on treating cancer—in fact, evolutionary approaches offer new and promising options for the disease’s prevention and treatments that aim at long-term management rather than simple eradication. Looking across species—from sponges and cacti to dogs and elephants—we are discovering new mechanisms of tumor suppression and the many ways that multicellular life-forms have evolved to keep cancer under control. By accepting that cancer is a part of our biological past, present, and future—and that we cannot win a war against evolution—treatments can become smarter, more strategic, and more humane. Unifying the latest research from biology, ecology, medicine, and social science, The Cheating Cell challenges us to rethink cancer’s fundamental nature and our relationship to it.

Frontiers in Cancer Research

Frontiers in Cancer Research
  • Author : Carlo C. Maley,Mel Greaves
  • Publisher :Unknown
  • Release Date :2016-11-21
  • Total pages :258
  • ISBN : 9781493964604
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Summary : This is the ideal book for anyone contemplating starting a career in, or shifting their career to, studying the dynamics that drive cancer progression and its response to therapy. Topics include the theory and population genetics of cancers, genetic diversity within tumors (intra-tumor heterogeneity), understanding how mutant clones expand in tissues, the role of cancer stem cells in the dynamics of tumors, the evolution of metastasis, and how to improve cancer therapy by addressing the evolution of cancers in response to our interventions. There are also chapters on the patterns of cancer susceptibility in humans due to a mismatch between our modern environment and the environment in which our ancestors evolved, as well as a chapter on the evolution of cancer suppression mechanisms that have evolved in different species, particularly the large long-lived animals like elephants and whales that are better at suppressing cancers than humans. This book serves as a primer on the evolutionary and ecological theory of cancer- the framework upon which all the details of cancer may be hung. It is ideal for oncologists and cancer researchers interested in evolutionary theory, and evolutionary biologists and ecologists interested in gaining insights into cancer development and prevention.

Introduction to Mathematical Oncology

Introduction to Mathematical Oncology
  • Author : Yang Kuang,John D. Nagy,Steffen E. Eikenberry
  • Publisher :Unknown
  • Release Date :2018-09-03
  • Total pages :470
  • ISBN : 9781498752978
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Summary : Introduction to Mathematical Oncology presents biologically well-motivated and mathematically tractable models that facilitate both a deep understanding of cancer biology and better cancer treatment designs. It covers the medical and biological background of the diseases, modeling issues, and existing methods and their limitations. The authors introduce mathematical and programming tools, along with analytical and numerical studies of the models. They also develop new mathematical tools and look to future improvements on dynamical models. After introducing the general theory of medicine and exploring how mathematics can be essential in its understanding, the text describes well-known, practical, and insightful mathematical models of avascular tumor growth and mathematically tractable treatment models based on ordinary differential equations. It continues the topic of avascular tumor growth in the context of partial differential equation models by incorporating the spatial structure and physiological structure, such as cell size. The book then focuses on the recent active multi-scale modeling efforts on prostate cancer growth and treatment dynamics. It also examines more mechanistically formulated models, including cell quota-based population growth models, with applications to real tumors and validation using clinical data. The remainder of the text presents abundant additional historical, biological, and medical background materials for advanced and specific treatment modeling efforts. Extensively classroom-tested in undergraduate and graduate courses, this self-contained book allows instructors to emphasize specific topics relevant to clinical cancer biology and treatment. It can be used in a variety of ways, including a single-semester undergraduate course, a more ambitious graduate course, or a full-year sequence on mathematical oncology.

Unsolved Problems in Ecology

Unsolved Problems in Ecology
  • Author : Andrew Dobson,David Tilman,Robert D. Holt
  • Publisher :Unknown
  • Release Date :2020-05-19
  • Total pages :384
  • ISBN : 9780691199832
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Summary : Leading ecologists discuss some of the most compelling open questions in the field today Unsolved Problems in Ecology brings together many of the world's leading ecologists to discuss the most fundamental research questions confronting the field today. This diverse and thought-provoking collection of essays spans virtually all of the key subfields of the discipline, from behavioral and evolutionary ecology to population biology, community ecology, ecosystem ecology, disease ecology, and conservation biology. These essays are intended to stoke curiosity, challenge prevailing wisdom, and provoke new ways of thinking about ecology in light of new technologies and unprecedented environmental challenges brought on by climate and land-use change. Authoritative and accessible, Unsolved Problems in Ecology is ideal for graduate students in the early stages of their scientific careers and an essential resource for seasoned ecologists looking for exciting new directions to take their research. Sheds light on modern ecology's most important and compelling open questions Features thought-provoking contributions from more than two dozen world-class ecologists Covers behavior, evolution, communities, ecosystems, resource management, and more Discusses ways to raise the financial and intellectual profile of the discipline An invaluable resource for graduate students as well as seasoned ecologists

Frontiers in Ecology, Evolution and Complexity

Frontiers in Ecology, Evolution and Complexity
  • Author : Mariana Benítez,Octavio Miramontes,Alfonso Valiente-Banuet
  • Publisher :Unknown
  • Release Date :2014-07-08
  • Total pages :266
  • ISBN : 9781938128059
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Summary : Advances in molecular biology, remote sensing, systems biology, bioinformatics, non-linear science, the physics of complex systems and other fields have rendered a great amount of data that remain to be integrated into models and theories that are capable of accounting for the complexity of ecological systems and the evolutionary dynamics of life. It is thus necessary to provide a solid basis to discuss and reflect on these and other challenges both at the local and global scales. This volume aims to delineate an integrative and interdisciplinary view that suggests new avenues in research and teaching, critically discusses the scope of the diverse methods in the study of complex systems, and points at key open questions. Finally, this book will provide students and specialists with a collection of high quality open access essays that will contribute to integrate Ecology, Evolution and Complexity in the context of basic research and in the field of Sustainability Sciences.

Piper: A Model Genus for Studies of Phytochemistry, Ecology, and Evolution

Piper: A Model Genus for Studies of Phytochemistry, Ecology, and Evolution
  • Author : Lee A. Dyer,Aparna Palmer
  • Publisher :Unknown
  • Release Date :2012-12-06
  • Total pages :214
  • ISBN : 9780387305998
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Summary : Piper is an economically and ecologically important genus of plant that includes a fascinating array of species for studying natural history, natural products chemistry, community ecology, and evolutionary biology. The diversification of this taxon is unique and of great importance in understanding the evolution of plants. The diversity and ecological relevance of this genus makes it an obvious candidate for ecological and evolutionary studies, but surprisingly, most research on Piper spp. to-date has focused on the more economically important plants P. nigrum (black pepper), P. methysticum (kava), and P. betle (betel leaf). While this book does address the applied techniques of studying Piper, its focus is more on Piper in its natural setting. Piper: A Model Genus for Studies of Phytochemistry, Ecology, and Evolution synthesizes existing data and provides an outline for future investigations of the chemistry, ecology, and evolution of this taxon, while examining its key themes of Piper as a model genus for ecological and evolutionary studies, the important ecological roles of Piper species in lowland wet forests, and the evolution of distinctive Piper attributes. This volume has a place in the libraries of those studying or working in the fields of ecology, evolutionary biology, natural products chemistry, invasive species biology, pharmaceutics, and ethnobotany.

Dynamics of Cancer

Dynamics of Cancer
  • Author : Dominik Wodarz,Natalia L Komarova
  • Publisher :Unknown
  • Release Date :2014-04-24
  • Total pages :532
  • ISBN : 9789814566384
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Summary : The book aims to provide an introduction to mathematical models that describe the dynamics of tumor growth and the evolution of tumor cells. It can be used as a textbook for advanced undergraduate or graduate courses, and also serves as a reference book for researchers. The book has a strong evolutionary component and reflects the viewpoint that cancer can be understood rationally through a combination of mathematical and biological tools. It can be used both by mathematicians and biologists. Mathematically, the book starts with relatively simple ordinary differential equation models, and subsequently explores more complex stochastic and spatial models. Biologically, the book starts with explorations of the basic dynamics of tumor growth, including competitive interactions among cells, and subsequently moves on to the evolutionary dynamics of cancer cells, including scenarios of cancer initiation, progression, and treatment. The book finishes with a discussion of advanced topics, which describe how some of the mathematical concepts can be used to gain insights into a variety of questions, such as epigenetics, telomeres, gene therapy, and social interactions of cancer cells. Contents:Teaching GuideCancer and Somatic EvolutionMathematical Modeling of TumorigenesisBasic Growth Dynamics and Deterministic Models:Single Species GrowthTwo-Species Competition DynamicsCompetition Between Genetically Stable and Unstable CellsChromosomal Instability and Tumor GrowthAngiogenesis Inhibitors, Promoters, and Spatial GrowthEvolutionary Dynamics and Stochastic Models:Evolutionary Dynamics of Tumor Initiation Through Oncogenes: The Gain-of-Function ModelEvolutionary Dynamics of Tumor Initiation Through Tumor-Suppressor Genes: The Loss-of-Function Model and Stochastic TunnelingMicrosatellite and Chromosomal Instability in Sporadic and Familial Colorectal CancersEvolutionary Dynamics in Hierarchical PopulationsSpatial Evolutionary Dynamics of Tumor InitiationComplex Tumor Dynamics in SpaceStochastic Modeling of Cellular Growth, Treatment, and Resistance GenerationEvolutionary Dynamics of Drug Resistance in Chronic Myeloid LeukemiaAdvanced Topics:Evolutionary Dynamics of Stem-Cell Driven Tumor GrowthTumor Growth Kinetics and Disease ProgressionEpigenetic Changes and the Rate of DNA MethylationTelomeres and Cancer ProtectionGene Therapy and Oncolytic Virus TherapyImmune Responses, Tumor Growth, and TherapiesTowards Higher Complexities: Social Interactions Readership: Researchers in mathematical biology, mathematical modeling, biology, mathematical oncology. Keywords:Mathematical Oncology;Dynamics;Evolution;Evolutionary Dynamics;Cancer;Mathematical Models;Somatic Evolution;TeachingKey Features:Both a reference book for the topic, and provides material for undergraduate and graduate coursesTries to bridge the divide between mathematicians and biologists, which is also reflected in the backgrounds of the two authorsShows how mathematical concepts can be translated into experimentally and clinically useful insightsRooted in evolutionary biology, the book handles this very complex phenomenon in an intuitive and mathematically elegant wayContains problems and research projects for each topic10 pages of figures in color

Saving the Tasmanian Devil

Saving the Tasmanian Devil
  • Author : Carolyn Hogg,Samantha Fox,David Pemberton,Katherine Belov
  • Publisher :Unknown
  • Release Date :2019-08-01
  • Total pages :348
  • ISBN : 9781486307197
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Summary : The Tasmanian devil is threatened by Devil Facial Tumour Disease (DFTD), a transmissible form of cancer that has reduced the population by over 80%. Persecution, extreme climate events, vehicle collision and habitat destruction also put pressure on this endangered species. The recovery effort to save the Tasmanian devil commenced over 15 years ago as a collaborative initiative between the Tasmanian government, the Australian government, the Zoo and Aquarium Association Australasia, and many research institutions. Saving the Tasmanian Devil documents the journey taken by partner organisations in discovering what DFTD is, the effect it has on wild devil populations, and the outcomes achieved through research and management actions. Chapters describe all aspects of devil conservation, including the captive devil populations, applied pathology, immunology and genetic research findings, adaptive management, and the importance of advocacy and partnerships. This book will provide management practitioners and conservation scientists with insight into the complexities of undertaking a program of this scale, and will also be of value to researchers, students and others interested in conservation.

Cancer Evolution

Cancer Evolution
  • Author : Charles Swanton
  • Publisher :Unknown
  • Release Date :2017
  • Total pages :350
  • ISBN : 1621821439
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Summary : Tumor progression is driven by mutations that confer growth advantages to different subpopulations of cancer cells. As a tumor grows, these subpopulations expand, accumulate new mutations, and are subjected to selective pressures from the environment, including anticancer interventions. This process, termed clonal evolution, can lead to the emergence of therapy-resistant tumors and poses a major challenge for cancer eradication efforts. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine examines cancer progression as an evolutionary process and explores how this way of looking at cancer may lead to more effective strategies for managing and treating it. The contributors review efforts to characterize the subclonal architecture and dynamics of tumors, understand the roles of chromosomal instability, driver mutations, and mutation order, and determine how cancer cells respond to selective pressures imposed by anticancer agents, immune cells, and other components of the tumor microenvironment. They compare cancer evolution to organismal evolution and describe how ecological theories and mathematical models are being used to understand the complex dynamics between a tumor and its microenvironment during cancer progression. The authors also discuss improved methods to monitor tumor evolution (e.g., liquid biopsies) and the development of more effective strategies for managing and treating cancers (e.g., immunotherapies). This volume will therefore serve as a vital reference for all cancer biologists as well as anyone seeking to improve clinical outcomes for patients with cancer.

Evolutionary Dynamics

Evolutionary Dynamics
  • Author : Martin A. Nowak
  • Publisher :Unknown
  • Release Date :2006-09-29
  • Total pages :377
  • ISBN : 9780674417755
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Summary : At a time of unprecedented expansion in the life sciences, evolution is the one theory that transcends all of biology. Any observation of a living system must ultimately be interpreted in the context of its evolution. Evolutionary change is the consequence of mutation and natural selection, which are two concepts that can be described by mathematical equations. Evolutionary Dynamics is concerned with these equations of life. In this book, Martin A. Nowak draws on the languages of biology and mathematics to outline the mathematical principles according to which life evolves. His work introduces readers to the powerful yet simple laws that govern the evolution of living systems, no matter how complicated they might seem. Evolution has become a mathematical theory, Nowak suggests, and any idea of an evolutionary process or mechanism should be studied in the context of the mathematical equations of evolutionary dynamics. His book presents a range of analytical tools that can be used to this end: fitness landscapes, mutation matrices, genomic sequence space, random drift, quasispecies, replicators, the Prisoner’s Dilemma, games in finite and infinite populations, evolutionary graph theory, games on grids, evolutionary kaleidoscopes, fractals, and spatial chaos. Nowak then shows how evolutionary dynamics applies to critical real-world problems, including the progression of viral diseases such as AIDS, the virulence of infectious agents, the unpredictable mutations that lead to cancer, the evolution of altruism, and even the evolution of human language. His book makes a clear and compelling case for understanding every living system—and everything that arises as a consequence of living systems—in terms of evolutionary dynamics.

Biodiversity, Natural Products and Cancer Treatment

Biodiversity, Natural Products and Cancer Treatment
  • Author : Victor Kuete,Thomas Efferth
  • Publisher :Unknown
  • Release Date :2014-07-15
  • Total pages :412
  • ISBN : 9789814583527
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Summary : This book is the first of its kind in bringing together biodiversity, chemical ecology, phytochemistry and cancer therapy. The highlight of the book is an exhaustive compilation of scientific data on biodiversity of medicinal plants, biodiversity and metagenomics, chemical ecology of medicinal plants, chemical ecology of marine organisms, natural products from terrestrial microbial organisms with activity towards cancer cells, marine organisms, ethnopharmacology and phytotherapy, contribution of African flora in world fight against cancer, natural products derived from terrestrial plants with activity towards cancer cells and established anticancer drugs from natural origin. The book discusses the state-of-the-art of each topic to serve as reference resource tools for graduate students as well as scientists and scholars in pharmaceutical sciences, pharmacology, organic chemistry and biochemistry, pharmacognosy, phytochemistry, ethnomedicine and ethnopharmacology, complementary and alternative medicine, medical and public health sciences and others. It includes cutting-edge developments in anticancer discovery from both medicinal plants and organisms. Contents:Biodiversity of Medicinal Plants (Kirsten Yacoub, Katharina Cibis and Corinna Risch)Biodiversity and Metagenomics (Eva-Maria Surmann and Thomas Efferth)Chemical Ecology of Medicinal Plants (Christian Kersten, Stephanie Lenz and Janina Wich)Chemical Ecology of Marine Organisms (André Antunes and Thomas Efferth)Natural Products from Terrestrial Microbial Organisms with Cytotoxic Cell Cycle Inhibitors (Theresa Dreis, Caroline Gartner, Julia Krebs and Mathias Schneider)Marine Compounds (Jennifer Honek and Thomas Efferth)Ethnopharmacology and Phytotherapy (Ariane Löhnert, Susanne Löhnert, Viktoriya Mogilevskaya and Sandra Schick)Contribution of African Flora in a Global Fight Against Cancer (Victor Kuete and Thomas Efferth)Natural Products Derived from Terrestrial Plants with Activity Towards Cancer Cells (Sonia Falenska, Ina Kirmes, Stephanie Kletting, Irini Karagianni and Karen Duffy)Established Anticancer Drugs from Natural Origin (Clara Becker, Kerstin Hoffmann, Laura Hoffmann, Tanya King, Franziska Faulstich, Katrin Viertel, Victor Kuete and Thomas Efferth) Readership: Graduate students and scientists in pharmaceutical sciences, pharmacology, organic chemistry, biochemistry, pharmacognosy, phytochemistry, ethnomedicine & ethnopharmacology, compementary & alternative medicine, public health. Key Features:This book is the first of its kind bringing together biodiversity, chemical ecology, phytochemistry and cancer therapyThe book provides the state-of-the-art in anticancer discovery from medicinal plantsThe book also provides the state-of-the-art in anticancer discovery from marine organismsKeywords:Biodiversity;Cancer;Marine Products;Natural Products;Established Drugs

Group Work with Adolescents, Third Edition

Group Work with Adolescents, Third Edition
  • Author : Andrew Malekoff
  • Publisher :Unknown
  • Release Date :2015-11-17
  • Total pages :438
  • ISBN : 9781462525805
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Summary : A trusted course text and professional resource, this comprehensive book delves into all aspects of planning and conducting strengths-based group work with adolescents. In an accessible, down-to-earth style, Andrew Malekoff spells out the principles of effective group practice. Extensive clinical illustrations show how successful group leaders engage teens in addressing tough issues--including violence, sexuality, prejudice, social isolation, and substance abuse--in a wide range of settings. Normative issues that adolescents face in the multiple contexts of their lives are lucidly explained. Packed with creative ideas and activities, the book helps readers develop their skills as confident, reflective practitioners. New to This Edition *Significantly revised chapters on group work essentials, school-based practice, and trauma. *Additional topics: social media and cyberbullying, expressive and animal-assisted therapies, mindfulness, adolescent brain development, and more. *Updated practice principles, information, and references. *Numerous new practice illustrations.

Parasitism

Parasitism
  • Author : Claude Combes
  • Publisher :Unknown
  • Release Date :2001
  • Total pages :728
  • ISBN : 9780226114460
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Summary : In Parasitism, Claude Combes explores the fascinating adaptations parasites have developed through their intimate interactions with their hosts. He begins with the biology of parasites—their life cycles, habitats, and different types of associations with their hosts. Next he discusses genetic interactions between hosts and parasites, and he ends with a section on the community ecology of parasites and their role in the evolution of their hosts. Throughout the book Combes enlivens his discussion with a wealth of concrete examples of host-parasite interactions.

Citrus

Citrus
  • Author : Pierre Laszlo
  • Publisher :Unknown
  • Release Date :2008-10
  • Total pages :252
  • ISBN : 9780226470283
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Summary : Laszlo traces the spectacular rise and spread of citrus across the globe, from southeast Asia in 4000 BC to modern Spain and Portugal, whose explorers inroduced the fruit to the Americas. This book explores the numerous roles that citrus has played in agriculture, horticulture, cooking, nutrition, religion, and art.

Why We Get Sick

Why We Get Sick
  • Author : Randolph M. Nesse, MD,George C. Williams
  • Publisher :Unknown
  • Release Date :2012-02-08
  • Total pages :304
  • ISBN : 9780307816009
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Summary : The next time you get sick, consider this before picking up the aspirin: your body may be doing exactly what it's supposed to. In this ground-breaking book, two pioneers of the science of Darwinian medicine argue that illness as well as the factors that predispose us toward it are subject to the same laws of natural selection that otherwise make our bodies such miracles of design. Among the concerns they raise: When may a fever be beneficial? Why do pregnant women get morning sickness? How do certain viruses "manipulate" their hosts into infecting others? What evolutionary factors may be responsible for depression and panic disorder? Deftly summarizing research on disorders ranging from allergies to Alzheimer's, and form cancer to Huntington's chorea, Why We Get Sick, answers these questions and more. The result is a book that will revolutionize our attitudes toward illness and will intrigue and instruct lay person and medical practitioners alike.

Partnerships, Governance and Sustainable Development

Partnerships, Governance and Sustainable Development
  • Author : P. Glasbergen,Frank Biermann,A. P. J. Mol
  • Publisher :Unknown
  • Release Date :2007
  • Total pages :314
  • ISBN : 9781847208668
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Summary : . . . this is a book to read for anybody who wants a good overview of ongoing research on environmental partnerships in public administration, business administration, political science and sociology. Thomas Sikor, Journal of Integrative Environmental Sciences The profit of this book is the well-proportioned mixture of theoretical reflections . . . and empirical findings, mostly presented in the form of case studies. . . the volume offers a well-structured and recommendable account of the current state of governance and partnerships in the field of sustainable development. Thomas Krumm, Political Studies Review This well-structured volume brings together a group of leading experts on an important emerging topic of global and local environmental policy. The book is highly recommended for every student and scholar in the field of environmental governance. Martin Jänicke, Freie Universität Berlin, Germany Partnerships have emerged as a critical best practice in the pursuit of sustainability. Glasbergen, Biermann and Mol s book explores the partnership issue from a variety of empirical and theoretical perspectives highlighting how to understand them and what (not) to do. Highly recommended. Daniel C. Esty, Yale University, US This significant study discusses the emergence of partnerships for sustainable development as an innovative, and potentially influential, new type of governance. With contributions from leading experts in the field, the partnership paradigm is discussed and the contributors explore the process, extent and circumstances under which partnerships can improve the legitimacy and effectiveness of governance for sustainable development. Scientific research on partnerships within the context of governance theory is fairly new, and there is a clear need to systemize a knowledge base to further define the international research agenda. In addition, there is an urgent demand from governments and international organizations, as well as from non-governmental actors, for strategic insights to build upon their activities in this field. This book is designed to address the questions, debates and agendas related to this new mode of governance. This multi-disciplinary book brings together unique perspectives from organizational theory, policy science, sociology and political science. As such, it will be warmly welcomed by academics of environmental policy and politics as well as scholars and researchers interested in governance for sustainable development. It will also appeal to public policy scholars.

Cattle Bring Us to Our Enemies

Cattle Bring Us to Our Enemies
  • Author : J. Terrence McCabe
  • Publisher :Unknown
  • Release Date :2010-02-11
  • Total pages :320
  • ISBN : 9780472026210
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Summary : An in-depth look at the ecology, history, and politics of land use among the Turkana pastoral people in Northern Kenya Based on sixteen years of fieldwork among the pastoral Turkana people, McCabe examines how individuals use the land and make decisions about mobility, livestock, and the use of natural resources in an environment characterized by aridity, unpredictability, insecurity, and violence. The Turkana are one of the world's most mobile peoples, but understanding why and how they move is a complex task influenced by politics, violence, historical relations among ethnic groups, and the government, as well as by the arid land they call home. As one of the original members of the South Turkana Ecosystem Project, McCabe draws on a wealth of ecological data in his analysis. His long-standing relationship with four Turkana families personalize his insights and conclusions, inviting readers into the lives of these individuals, their families, and the way they cope with their environment and political events in daily life. J. Terrence McCabe is Associate Professor of Anthropology, University of Colorado at Boulder.

Genomic and Precision Medicine

Genomic and Precision Medicine
  • Author : Geoffrey S. Ginsburg,Huntington F Willard
  • Publisher :Unknown
  • Release Date :2016-11-22
  • Total pages :398
  • ISBN : 9780128006566
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Summary : Genomic and Precision Medicine: Translation and Implementation highlights the various points along the continuum from health to disease where genomic information is impacting clinical decision-making and leading to more personalization of health care. The book pinpoints the challenges, barriers, and solutions that have been, or are being, brought forward to enable translation of genome based technologies into health care. A variety of infrastructure (data systems and EMRs), policy (regulatory, reimbursement, privacy), and research (comparative effectiveness research, learning health system approaches) strategies are also discussed. Readers will find this volume to be an invaluable resource for the translational genomics and implementation science that is required to fully realize personalized health care. Provides a comprehensive volume on the translation and implementation of biology into health care provision Presents succinct commentary and key learning points that will assist readers with their local needs for translation and implementation Includes an up-to-date overview on major ‘translational events’ in genomic and personalized medicine, along with lessons learned

Ornithology

Ornithology
  • Author : Michael L. Morrison,Amanda D. Rodewald,Gary Voelker,Melanie R. Colón,Jonathan F. Prather
  • Publisher :Unknown
  • Release Date :2018-09-03
  • Total pages :1016
  • ISBN : 9781421424712
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Summary : Wood, Robert M. Zink, Benjamin Zuckerberg

The Theory of Evolution

The Theory of Evolution
  • Author : Samuel M. Scheiner,David P. Mindell
  • Publisher :Unknown
  • Release Date :2020-04-03
  • Total pages :464
  • ISBN : 9780226671338
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Summary : Darwin’s nineteenth-century writings laid the foundations for modern studies of evolution, and theoretical developments in the mid-twentieth century fostered the Modern Synthesis. Since that time, a great deal of new biological knowledge has been generated, including details of the genetic code, lateral gene transfer, and developmental constraints. Our improved understanding of these and many other phenomena have been working their way into evolutionary theory, changing it and improving its correspondence with evolution in nature. And while the study of evolution is thriving both as a basic science to understand the world and in its applications in agriculture, medicine, and public health, the broad scope of evolution—operating across genes, whole organisms, clades, and ecosystems—presents a significant challenge for researchers seeking to integrate abundant new data and content into a general theory of evolution. This book gives us that framework and synthesis for the twenty-first century. The Theory of Evolution presents a series of chapters by experts seeking this integration by addressing the current state of affairs across numerous fields within evolutionary biology, ranging from biogeography to multilevel selection, speciation, and macroevolutionary theory. By presenting current syntheses of evolution’s theoretical foundations and their growth in light of new datasets and analyses, this collection will enhance future research and understanding.