Download Energy Metabolism In Heart Failure Book PDF

Download full Energy Metabolism In Heart Failure books PDF, EPUB, Tuebl, Textbook, Mobi or read online Energy Metabolism In Heart Failure anytime and anywhere on any device. Get free access to the library by create an account, fast download and ads free. We cannot guarantee that every book is in the library.

Cardiac Energy Metabolism in Health and Disease

Cardiac Energy Metabolism in Health and Disease
  • Author : Gary D. Lopaschuk,Naranjan S. Dhalla
  • Publisher :Unknown
  • Release Date :2014-08-22
  • Total pages :295
  • ISBN : 9781493912278
GET BOOK HERE

Summary : The heart has a very high energy demand but very little energy reserves. In order to sustain contractile function, the heart has to continually produce a large amount of ATP. The heart utilizes free fatty acids mainly and carbohydrates to some extent as substrates for making energy and any change in this energy supply can seriously compromise cardiac function. It has emerged that alterations in cardiac energy metabolism are a major contributor to the development of a number of different forms of heart disease. It is also now known that optimizing energy metabolism in the heart is a viable and important approach to treating various forms of heart disease. Cardiac Energy Metabolism in Health and Disease describes the research advances that have been made in understanding what controls cardiac energy metabolism at molecular, transcriptional and physiological levels. It also describes how alterations in energy metabolism contribute to the development of heart dysfunction and how optimization of energy metabolism can be used to treat heart disease. The topics covered include a discussion of the effects of myocardial ischemia, diabetes, obesity, hypertrophy, heart failure, and genetic disorders of mitochondrial oxidative metabolism on cardiac energetics. The treatment of heart disease by optimizing energy metabolism is also discussed, which includes increasing overall energy production as well as increasing the efficiency of energy production and switching energy substrate preference of the heart. This book will be a valuable source of information to graduate students, postdoctoral fellows, and investigators in the field of experimental cardiology as well as biochemists, physiologists, pharmacologists, cardiologists, cardiovascular surgeons and other health professionals.

Novel Concepts in Cardiac Energy Metabolism: From Biology to Disease

Novel Concepts in Cardiac Energy Metabolism: From Biology to Disease
  • Author : Thomas Pulinilkunnil,Petra Kienesberger,Jeevan Nagendran
  • Publisher :Unknown
  • Release Date :2019-08-08
  • Total pages :89
  • ISBN : 9782889459384
GET BOOK HERE

Summary :

Myocardial Energy Metabolism

Myocardial Energy Metabolism
  • Author : J.W. de Jong
  • Publisher :Unknown
  • Release Date :2012-12-06
  • Total pages :310
  • ISBN : 9789400913196
GET BOOK HERE

Summary :

The Scientist's Guide to Cardiac Metabolism

The Scientist's Guide to Cardiac Metabolism
  • Author : Michael Schwarzer,Torsten Doenst
  • Publisher :Unknown
  • Release Date :2015-11-04
  • Total pages :240
  • ISBN : 9780128026144
GET BOOK HERE

Summary : The Scientists Guide to Cardiac Metabolism combines the basic concepts of substrate metabolism, regulation, and interaction within the cell and the organism to provide a comprehensive introduction into the basics of cardiac metabolism. This important reference is the perfect tool for newcomers in cardiac metabolism, providing a basic understanding of the metabolic processes and enabling the newcomer to immediately communicate with the expert as substrate/energy metabolism becomes part of projects. The book is written by established experts in the field, bringing together all the concepts of cardiac metabolism, its regulation, and the impact of disease. Provides a quick and comprehensive introduction into cardiac metabolism Contains an integrated view on cardiac metabolism and its interrelation in metabolism with other organs Presents insights into substrate metabolism in relation to intracellular organization and structure as well as whole organ function Includes historical perspectives that reference important investigators that have contributed to the development of the field

ATP and the Heart

ATP and the Heart
  • Author : Joanne S. Ingwall
  • Publisher :Unknown
  • Release Date :2012-12-06
  • Total pages :244
  • ISBN : 9781461510932
GET BOOK HERE

Summary : ATP plays a central role in the two leading causes of cardiac morbidity and mortality in the western world: ischemia and heart failure. We are in our infancy applying what is known about biology and chemistry of ATP toward developing effective therapies for these diseases. In this volume, the current understanding of the chemistry and biology of ATP specifically in the cardiomyocyte is presented. New insights into ATP have been gleaned using biophysical techniques allowing dynamic measurement of chemical events in the intact beating heart and using new animal models in which cardiac proteins are either over expressed, deleted or harbor specific mutations. This book provides a summary of the basic understanding and includes illustrations of why ATP and the Heart is important to both the clinician and scientist.

The Failing Heart

The Failing Heart
  • Author : Naranjan S. Dhalla
  • Publisher :Unknown
  • Release Date :1995
  • Total pages :524
  • ISBN : UOM:39015035021438
GET BOOK HERE

Summary : (Proc./Intl Conf. 5/94) Topics inc. atrial defibrillation & congestive heart failure trmt of symptomatic heart failure.

Mitochondrial Diseases

Mitochondrial Diseases
  • Author : Eylem Taskin,Celal Guven,Yusuf Sevgiler
  • Publisher :Unknown
  • Release Date :2018-08-29
  • Total pages :496
  • ISBN : 9781789236743
GET BOOK HERE

Summary : Mitochondria are crucial organelles for any cell type. Mitochondria take responsibility for not only energy production but also regulation of cell death, also called apoptosis; calcium storage; and heat production. Therefore, mitochondrial disease is implicated in the mode of action of many harmful factors for cells such as drugs and environmental contaminants, dysfunction of the oxygen transport system, malnutrition, intense exercise, and genetic variations. This book presents up-to-date knowledge about mitochondrial disease and its complex relation to some diseases such as cardiac failure, cancer, and Alzheimer's and Parkinson's diseases. This book will, therefore, be essential for readers who are interested in life sciences, especially in medicine.

Inflammation in Heart Failure

Inflammation in Heart Failure
  • Author : Matthijs Blankesteijn,Raffaele Altara
  • Publisher :Unknown
  • Release Date :2014-12-05
  • Total pages :220
  • ISBN : 9780128004852
GET BOOK HERE

Summary : Inflammation in Heart Failure, edited by W. Matthijs Blankesteijn and Raffaele Altara, is the first book in a decade to provide an in-depth assessment on the causes, symptoms, progression and treatments of cardiac inflammation and related conditions. This reference uses two decades of research to introduce new methods for identifying inflammatory benchmarks from early onset to chronic heart failure and specifically emphasizes the importance of classifying at-risk subgroups within large populations while determining the patterns of cytokines in such classifications. Further, the book details clinical applications of the pathophysiological mechanisms of heart failure, diagnosis and therapeutic strategies. Inflammation in Heart Failure’s breadth of subject matter, easy-to-follow structure, portability, and high-quality illustrations create an accessible benefit for researchers, clinicians and students. Presents updated information and research on the relevant inflammatory mediators of heart failure to aid in targeting future translational research as well as the improvement of early diagnosis and treatment Provides research into better understanding the different inflammatory mediators that signal the underlying diseases that potentially lead to heart failure Contains 20 years of research, offering a brief overview of the topic leading to current opinions on, and treatment of, heart failure Provides a structured, systematic and balanced overview of the role of inflammation in heart failure making it a useful resource for researchers and clinicians, as well as those studying cardiovascular diseases

Oxford Textbook of Heart Failure

Oxford Textbook of Heart Failure
  • Author : Theresa A. McDonagh,Roy S. Gardner,Andrew L. Clark,Henry Dargie
  • Publisher :Unknown
  • Release Date :2011-07-14
  • Total pages :641
  • ISBN : 9780199577729
GET BOOK HERE

Summary : The Oxford Textbook of Heart Failure takes the reader from an understanding of the basic mechanisms of heart failure, through to an appreciation of the complexities of heart failure management and the improvements possible with good treatment. Written by internationally renowned leaders in the field, this definitive textbook comprehensively covers all aspects necessary to manage a patient with heart failure, and is essential reading for consultant cardiologists, those in training, general physicians and those caring of the elderly, cardiothoracic surgeons, primary care doctors, pharmacists, and specialist nurses. The online version of the Oxford Textbook of Heart Failure contains the full text of the print edition (which can be browsed by the contents list or searched), links from references in the text to external sources (via PubMed, ISI, and CrossRef), and over 300 figures and illustrations from the print edition, downloadable into PowerPoint.

The Sinatra Solution

The Sinatra Solution
  • Author : Stephen T. Sinatra
  • Publisher :Unknown
  • Release Date :2007-10
  • Total pages :253
  • ISBN : 1591202167
GET BOOK HERE

Summary : A board-certified cardiologist discusses the importance of energy metabolism on cardiovascular health and the positive impact three energy-supplying nutrients--CoQ10, Carnitine, and Ribose--have on the cardiovascular system.

Acute Heart Failure

Acute Heart Failure
  • Author : Alexandre Mebazaa,Mihai Gheorghiade,Faiez Zannad,Joseph E. Parrillo
  • Publisher :Unknown
  • Release Date :2009-12-24
  • Total pages :931
  • ISBN : 1846287820
GET BOOK HERE

Summary : For many years, there has been a great deal of work done on chronic congestive heart failure while acute heart failure has been considered a difficult to handle and hopeless syndrome. However, in recent years acute heart failure has become a growing area of study and this is the first book to cover extensively the diagnosis and management of this complex condition. The book reflects the considerable amounts of new data reported and many new concepts which have been proposed in the last 3-4 years looking at the epidemiology, diagnostic and treatment of acute heart failure.

Biophysics of the Failing Heart

Biophysics of the Failing Heart
  • Author : R. John Solaro,Jil C. Tardiff
  • Publisher :Unknown
  • Release Date :2013-08-13
  • Total pages :253
  • ISBN : 9781461476788
GET BOOK HERE

Summary : Subjects in the monograph “Biophysics of the Failing Heart” include state of the art chapters considering major biophysical mechanisms for why hearts responding to acquired or inherited stressors enter into maladaptive processes eventually leading to an inability of the heart to respond efficiently to hemodynamic loads especially during exercise. The chapters describe biophysical techniques that have been applied to determine the triggers for the heart failure process as well as the mechanisms for sustaining the disorders. These techniques include measurements of active and passive mechanical properties and hemodynamics at levels of organization ranging from molecules to hearts beating in situ. Biophysical concepts and approaches are also applied to determination of signaling and signal transduction, energetics, ionic currents, transport processes, electro-chemical and chemo-mechanical coupling. By its emphasis on biophysical aspects of a prevalent clinical condition, the monograph is unique in its perspective and focus. The breadth of information in the chapters all in one place will be of value to clinicians and researchers at all levels. Modern research approaches and clinical understanding of heart failure demands integration of multiple aspects of the disorders. In most cases, combinations of clinician scientists and researchers author the chapters. A main benefit of the book is couched in its didactic approach together with its emphasis on how biophysical concepts and techniques aid in diagnosis and development of new therapies.

Cardiac Energetics

Cardiac Energetics
  • Author : R. Jacob,Hanjoerg Just,C. Holubarsch
  • Publisher :Unknown
  • Release Date :2013-04-17
  • Total pages :425
  • ISBN : 9783662112892
GET BOOK HERE

Summary : Assessment of cardiac energetics at the level of ATP-synthesis, chemomechanical energy transformation and whole organ dynamics as a function of haemodynamic load, ventricular configuration and oxygen- and substrates supply is basic to understanding cardiac function under physiological and pathophysiological (hypertrophy, hypoxia, ischaemia and heart failure) conditions. Moreover, cardiac energetics should be an important consideration in the choice and application of drugs especially in the case of vasodilators, inotropic agents and in cardioprotective measures. Only by considering energetics at the subcellular, cellular, and whole-heart level we can arrive at a better understanding of cardiac performance and ultimately better clinical judgement and drug therapy. Quantification of myocardial energetics will also help to determine the optimal time for surgical interventions such as valvular replacement or aneurysm resection. The present volume is the outcome of an international symposium on cardiac energetics held in Gargellen/Montafon (Austria), June 1986. The contributions will certainly help bridge the existing gap between basic research involving isolated structures and that involving the whole organ, on the one hand, and render the results derived from basic research applicable to clinical problems, on the other hand.

Metabolomics

Metabolomics
  • Author : Jeevan Prasain
  • Publisher :Unknown
  • Release Date :2016-12-28
  • Total pages :216
  • ISBN : 9789535128533
GET BOOK HERE

Summary : Metabolomics: Fundamentals and Applications authoritatively presents the basic principles and applications of metabolomics. Topics covered in this book range from the analysis of metabolites from different biological sources and their data processing and statistical analysis. This book serves as a basic guide for a wide range of audiences from less familiar with metabolomics techniques to more experienced researchers seeking to understand complex biological systems from the systems biology approach.

Cardiotoxicity

Cardiotoxicity
  • Author : Wenyong Tan
  • Publisher :Unknown
  • Release Date :2018-11-14
  • Total pages :162
  • ISBN : 9781789842371
GET BOOK HERE

Summary : Cardiotoxicity may be caused by radiotherapy and/or anticancer agents for many malignancies, adverse effects of some drugs in the context of medical intervention or heavy metal intake, especially during the anticancer therapy. This book intends to bring forward the recent development in toxicities from cancer treatment. It updates the possible mechanisms of cardiotoxicities of some anticancer agents and the suggested prevention and treatment strategies. This book contains many valuable contributions from the researchers in oncology and cardiology as well as the clinicians who are experts in this field.

Cardiomyopathies

Cardiomyopathies
  • Author : Kaan Kırali
  • Publisher :Unknown
  • Release Date :2017-04-12
  • Total pages :470
  • ISBN : 9789535130390
GET BOOK HERE

Summary : Cardiomyopathies are the most featured cardiac pathologies in the twenty-first century, that threaten public health and burden healthcare budgets. This book is composed of the main topics on pathophysiology, general forms and specific types of cardiomyopathies and it also introduces new research in the field. Specific forms with or without genetic inheritance are discussed separately to attract the readers' attention on these topics. Well-known medical follow-up strategies occur ineffective at the end-stage heart failure, however, new surgical approaches can be an alternative for these patients to get a chance at the last crossroad and to improve their life quality and survival and also to gain or prolong time until possible heart transplantation.

Clinical Bioenergetics

Clinical Bioenergetics
  • Author : Sergej M. Ostojic
  • Publisher :Unknown
  • Release Date :2020-11-12
  • Total pages :716
  • ISBN : 9780128227725
GET BOOK HERE

Summary : Clinical Bioenergetics: From Pathophysiology to Clinical Translation provides recent developments surrounding the etiology and pathophysiology of inherited and acquired energy-delated disorders. Across 40 chapters, world leaders in bioenergetics and mitochondrial medicine discuss novel methodologies designed to identify deficiencies in cellular bioenergetics, as well as the safety and efficacy of emerging management strategies to address poor cellular bioenergetics. Topics discussed include the omics landscape of impaired mitochondrial bioenergetics, hormones, tissue bioenergetics and metabolism in humans. Disease-specific case studies, modes of analysis in clinical bioenergetics, and therapeutic opportunities for impaired bioenergetics, addressing both known treatment pathways and future directions for research, are discussed in-depth. Diseases and Disorders examined include brain injury, chronic fatigue syndrome, psychiatric disorders, pulmonary fibrosis, neurodegenerative disorders, heart failure, chronic kidney disease, obesity, and insulin resistance, among others. Provides a thorough discussion of foundational aspects of bioenergetics and disease, modes of analysis, and treatments for impaired bioenergetics Discusses the role of bioenergetics and treatment pathways in brain injury, chronic fatigue syndrome, psychiatric disorders, pulmonary fibrosis, neurodegenerative disorders, heart failure, chronic kidney disease, obesity, and insulin resistance, among other diseases and disorders Features chapter contributions from international leaders in translational bioenergetics research and clinical practice

Cardiac Metabolism in Health and Disease

Cardiac Metabolism in Health and Disease
  • Author : Salah Abdel-aleem,James E. Lowe
  • Publisher :Unknown
  • Release Date :2012-12-06
  • Total pages :202
  • ISBN : 9781461556879
GET BOOK HERE

Summary : This special issue of Molecular and Cellular Biochemistry contains original research papers as well as invited reviews focused in the field of cardiac metabolism and its regulation under normal and disease conditions. These papers cover many areas under intensive and rapid development such as the regulation of fatty acid oxidation in the heart, the role of cardiac glycogen during ischemia, the role of CPT I isoenzymes, the pathophysiology of diabetic cardiomyopathy, cardiac protection through regulation of energy production, the role of fatty acid binding protein under normal and pathological conditions, and several other important topics in this area of research. We hope that this special issue of Molecular and Cellular Biochemistry provides an up-to-date source of information for scientists and clinicians interested in the mechanism by which cardiac metabolism is regulated in health and disease and the mechanistic relationship between disturbances in cardiac metabolism and the genesis of cardiovascular diseases.

Heart Physiology and Pathophysiology

Heart Physiology and Pathophysiology
  • Author : Yoshihisa Kurachi,Andre Terzic,Michael V. Cohen
  • Publisher :Unknown
  • Release Date :2000-10-09
  • Total pages :1261
  • ISBN : 9780080533889
GET BOOK HERE

Summary : Heart Physiology and Pathophysiology, 4E, provides the foundation for the scientific understanding of heart function and dysfunction, and bridges the gap between basic cardiovascular science and clinical cardiology. This comprehensive text covers all the important aspects of the heart and vascular system. The most important and relevant disorders are presented, with emphasis on the mechanisms involved. The first three editions of this book developed a reputation as the leading reference in cardiovascular science for researchers and academic cardiologists. This recent edition has been updated, expanded, and includes a number of new contributors. It has also been remodeled to expand its usage as a text reference for cardiology residents, practicing cardiologists, and graduate students. Key Features * The most comprehensive book available on this topic * Clear, concise, and complete coverage of all important aspects of cardiovascular physiology/pathophysiology * Completely updated version of the foremost reference on cardiovascular science, including new information on pathophysiology and electrophysiology * Useful tool in bridging the gap between basic science, pathophysiology, and clinical cardiology

Heart Failure

Heart Failure
  • Author : Douglas L. Mann
  • Publisher :Unknown
  • Release Date :2004
  • Total pages :812
  • ISBN : UOM:39015052875088
GET BOOK HERE

Summary : Provides readers with a comprehensive bench-to-bench overview of the field of heart failure. Every attempt has been made to include novel chapters that have not heretofore been covered in traditional textbooks on heart failure. For example, one chapter addresses the new and emerging area of sleep-disordered breathing and heart. There are also unique chapters on the science and art of developing heart failure guidelines, as well as a chapter on clinical trial design in heart failure.

Hypoxia and Human Diseases

Hypoxia and Human Diseases
  • Author : Jing Zheng,Chi Zhou
  • Publisher :Unknown
  • Release Date :2017-02-01
  • Total pages :454
  • ISBN : 9789535128953
GET BOOK HERE

Summary : This book contains a total of 21 chapters, each of which was written by experts in the corresponding field. The objective of this book is to provide a comprehensive and updated overview of cellular and molecular mechanisms underlying hypoxia's impacts on human health, as well as current advances and future directions in the detection, recognition, and management of hypoxia-related disorders. This collection of articles provides a clear update in the area of hypoxia research for biomedical researchers, medical students, nurse practitioners, and practicing clinicians in the fields of high altitude biology, cardiovascular biology and medicine, tumor oncology, obstetrics, pediatrics, and orthodontics and for others who may be interested in hypoxia.