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Escherichia coli

Escherichia coli
  • Author : Michael Donnenberg
  • Publisher :Unknown
  • Release Date :2013-06-12
  • Total pages :612
  • ISBN : 9780123977779
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Summary : The 2e of Escherichia coli is a unique, comprehensive analysis of the biology and molecular mechanisms that enable this ubiquitous organism to thrive. Leading investigators in the field discuss the molecular basis of E. coli pathogenesis followed by chapters on genomics and evolution. Detailed descriptions of distinct strains reveal the molecular pathogenesis of each and the causes of intestinal and extra-intestinal infections in humans. This work concludes with a presentation of virulence factors common to two or more pathotypes. The book is a great resource for references and up-to-date knowledge for anyone who studies E. coli pathogenesis, either as established investigators or investigators new to the field. It is also an excellent text for those who teach mechanisms of pathogenesis to graduate students and medical students and wish to have a source of knowledge from which to develop lectures. Offers a single source of information of E. coli pathogenesis written by expert authors Presents comprehensive coverage on molecular mechanisms, biology, evolution and genomics and recent advances

Escherichia coli, a Versatile Pathogen

Escherichia coli, a Versatile Pathogen
  • Author : Gad Frankel,Eliora Z Ron
  • Publisher :Unknown
  • Release Date :2018-11-02
  • Total pages :242
  • ISBN : 9783319996646
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Summary : Escherichia coli is a facultative anaerobic Gamma-proteobacterium, which belongs to the family Enterobacteriaceae. While being an important constituent of the normal gut microbiota, specialized E. coli clones have acquired genetic elements that allow them to compete with the endogenous commensals, colonise normally sterile niches and cause disease. E. coli pathotypes can cause intestinal and extra intestinal infections (e.g. UTI, sepsis) and associate with mammalian cells while being extra- or intra-cellular. In recent years, E. coli infections have become a serious clinical problem, due to the rapid spread of antibiotic resistance. Thus, infections with intestinal E. coli (e.g. E. coli O104) or extraintestinal pathogenic strains (e.g. E. coli ST131) are becoming difficult to treat and are often lethal. Consequently, there is a pressing need to develop alternative control measures, including the identification of new drug targets and development of vaccines that offer lasting protection. This volume focuses on several types of E. coli infections (intestinal and extraintestinal), virulence factors, and E. coli pandemics. It addresses the problem of antibiotic resistance, and a dedicated chapter discusses the need to develop alternative control measures. Given its depth and breadth of coverage, the book will benefit all those interested in the biology, genetics, physiology and pathogenesis of E. coli, and in related vaccine development.

Detection and Typing Strategies for Pathogenic Escherichia coli

Detection and Typing Strategies for Pathogenic Escherichia coli
  • Author : Lucia Rivas,Glen E. Mellor,Kari Gobius,Narelle Fegan
  • Publisher :Unknown
  • Release Date :2015-01-28
  • Total pages :110
  • ISBN : 9781493923465
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Summary : This Brief will review the methods that are currently available for the detection, isolation, and typing of pathogenic E. coli with a particular focus on foodborne diseases caused by the Shiga toxigenic E. coli group, which have been implicated in a number of significant outbreaks in recent years. Pathogenic forms of E. coli can cause a variety of diarrheal diseases in hosts due to the presence of specific colonization and virulence factors, and pathogenicity-associated genes, which are generally not present in other E. coli. Six pathotypes of pathogenic E. coli are recognized (Shiga toxigenic E. coli, Enteropathogenic E. coli, Enterotoxigenic E. coli, Enteroinvasive E. coli, Enteroaggregative E. coli and Diffusely Adherent E. coli) and certain strains among these groups are major public health concerns due to the severity of disease that they can cause. Methods to detect and isolate these pathogens from a variety of sources are constantly evolving. In addition, the accumulation of knowledge on these pathogens allows for improved intervention strategies.

E. coli

E. coli
  • Author : Michael Donnenberg
  • Publisher :Unknown
  • Release Date :2002-10-09
  • Total pages :417
  • ISBN : 9780080494814
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Summary : Although most strains of E. coli bacteria are harmless and live in the intestines of healthy humans and animals, several strains can produce powerful toxins and cause severe illness in humans. This versatile pathogen is best known for being transmitted to humans through contaminated foods — such as undercooked meat and unpasteurized fruit juice — and has attracts much attention when serious outbreaks occur. E. coli is capable of causing a wide variety of diseases — from urinary tract infections to meningitis. A considerable amount of media coverage has recently been devoted to one particular strain of E. coli, responsible for an estimated 73,000 cases of infection and 61 deaths in the United States each year. Knowing more about the biology, the evolution, and the genetic basis of this pathogen is crucial to future prevention of infection and illness. Pathogenic E. coli is a unique, comprehensive analysis of the biology and molecular mechanisms that enable this ubiquitous organism to thrive. Leading investigators in the field discuss the molecular basis of E. coli pathogenesis followed by chapters on genomics and evolution. Detailed descriptions of distinct strains reveal the molecular pathogenesis of each and the causes of intestinal and extra-intestinal infections in humans. Pathogenic E. coli concludes with a presentation of virulance factors, common to two or more pathotypes. This unique collection presents timely and vital information on understanding the inner workings of E. coli, which will lend key insights into disease prevention research. Single source of information of E. coli pathogenesis Expert authors Comprehensive coverage Molecular mechanisms Biology, evolution and genomics Recent advances

Escherichia Coli Infections

Escherichia Coli Infections
  • Author : Shannon D. Manning
  • Publisher :Unknown
  • Release Date :2010
  • Total pages :134
  • ISBN : 9781604132533
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Summary : Introduces the bacterial disease, including how it can be transmitted, prevented, and treated, and describes the future of E. coli research.

Cyanobacteria: The Green E. coli

Cyanobacteria: The Green E. coli
  • Author : Anne M Ruffing,Toivo Kallas
  • Publisher :Unknown
  • Release Date :2016-03-16
  • Total pages :229
  • ISBN : 9782889198122
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Summary : As the world struggles to reduce its dependence on fossil fuels and curb greenhouse gas emissions, industrial biotechnology is also ‘going green.’ Escherichia coli has long been used as a model Gram-negative bacterium, not only for fundamental research, but also for industrial applications. Recently, however, cyanobacteria have emerged as candidate chassis for the production of commodity fuels and chemicals, utilizing CO2 and sunlight as the main nutrient requirements. In addition to their potential for reducing greenhouse gas emissions and lowering production costs, cyanobacteria have naturally efficient pathways for the production metabolites such as carotenoids, which are of importance in the nutraceutical industry. The unique metabolic and regulatory pathways present in cyanobacteria present new challenges for metabolic engineers and synthetic biologists. Moreover, their requirement for light and the dynamic regulatory mechanisms of the diurnal cycle further complicate the development and application of cyanobacteria for industrial applications. Consequently, significant advancements in cyanobacterial engineering and strain development are necessary for the development of a ‘green E. coli’. This Research Topic will focus on cyanobacteria as organisms of emerging industrial relevance, including research focused on the development of genetic tools for cyanobacteria, the investigation of new cyanobacterial strains, the construction of novel cyanobacterial strains via genetic engineering, the application of ‘omics’ tools to advance the understanding of engineered cyanobacteria, and the development of computational models for cyanobacterial strain development.

Escherichia coli

Escherichia coli
  • Author : Amidou Samie
  • Publisher :Unknown
  • Release Date :2017-07-12
  • Total pages :434
  • ISBN : 9789535133292
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Summary : Escherichia coli is a versatile organism and very diverse. Members of this species vary from very pathogenic agents causing different types of diseases including meningitis, gastroenteritis, and septicemia, just to cite a few, to harmless organisms living in the intestines of both humans and animals. E. coli has also been used as a model organism for most bacteria except a few. For this reason, its study provides a huge advantage and can help understand the mechanisms involved in different processes such as pathogenesis, environmental disinfection, nutrient utilization, antibiotic resistance, and diagnostic/detection methods, and these are indeed the topics discussed in this book. The book has been divided into four main sections representing the different facets of E. coli applications, which include disease, biotechnology, environmental engineering and innovative approaches to detection, and lastly its physiology and cell biology. Such processes can be applied to the study of other organisms as well considering the development of diversity; for example, many organisms are capable of horizontal gene transfer, which is capable of increasing the fitness of the bacterial organisms involved and has a great impact on the control of such bacterial organism.

Systems Biology and Biotechnology of Escherichia coli

Systems Biology and Biotechnology of Escherichia coli
  • Author : Sang Yup Lee
  • Publisher :Unknown
  • Release Date :2009-03-20
  • Total pages :462
  • ISBN : 9781402093944
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Summary : Systems biology is changing the way biological systems are studied by allowing us to examine the cell and organism as a whole. Systems biotechnology allows optimal design and development of upstream to downstream bioprocesses by taking a systems-approach. E. coli has been a model organism for almost all biological and biotechnological studies. This book brings together for the first time the state-of-the-art reviews by the world-leading experts on systems biology and biotechnological applications of E. coli. The topics covered include genomics and functional genomics, resources for systems biology, network analysis, genome-scale metabolic reconstruction, modelling and simulation, dynamic modelling and simulation, systems-level analysis of evolution, plasmids and expression systems, protein synthesis, production and export, engineering the central metabolism, synthetic biology, and systems metabolic engineering of E. coli. This book provides readers with guidance on how a complex biological system can be studied using E. coli as a model organism. It also presents how to perform synthetic biology and systems metabolic engineering studies on E. coli with successful examples, the approaches of which can be extended to other organisms. This book will be a complete resource for anyone interested in systems biology and biotechnology.

Escherichia coli in the Americas

Escherichia coli in the Americas
  • Author : Alfredo G. Torres
  • Publisher :Unknown
  • Release Date :2016-10-14
  • Total pages :384
  • ISBN : 9783319450926
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Summary : Bacterial diarrheal diseases remain an important leading cause of preventable death, especially among children under five in developing countries. In the American continent, diarrheal disease and other health complications caused by Escherichia coli constitute a major public health problem, and, therefore, several research groups have dedicated their effort to understand this pathogen and provide feasible solutions to prevent, treat and reduce E. coli infections. The Latin American Coalition for Escherichia coli Research (LACER) was created as a multidisciplinary network of international research groups working with E. coli with the ultimate goal of advancing understanding of E. coli, and to prepare the next generation of American E. coli investigators. As such, this book compiles the knowledge of these investigators about E. coli, a commensal bacteria living inside its host, and a pathogen causing disease in animals and humans. Escherichia coli in the Americas contains a series of 15 chapters written by experts, covering basic concepts regarding the different categories of E. coli, including their environmental niche, virulence mechanisms, host reservoir, and disease outcomes, as well as diagnosis, vaccine development and treatment. This book's target audience include trainees and students learning about the basic and clinical aspects of E. coli pathogenesis, as well as experts around the globe who wish to learn more about this pathogen and the public health impact this bacteria has in America.

Microbiology of Waterborne Diseases

Microbiology of Waterborne Diseases
  • Author : Steven L. Percival,Marylynn V. Yates,David Williams,Rachel Chalmers,Nicholas Gray
  • Publisher :Unknown
  • Release Date :2013-11-08
  • Total pages :696
  • ISBN : 9780124159761
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Summary : The second edition of Microbiology of Waterborne Diseases describes the diseases associated with water, their causative agents and the ways in which they gain access to water systems. The book is divided into sections covering bacteria, protozoa, and viruses. Other sections detail methods for detecting and identifying waterborne microorganisms, and the ways in which they are removed from water, including chlorine, ozone, and ultraviolet disinfection. The second edition of this handbook has been updated with information on biofilms and antimicrobial resistance. The impact of global warming and climate change phenomena on waterborne illnesses are also discussed. This book serves as an indispensable reference for public health microbiologists, water utility scientists, research water pollution microbiologists environmental health officers, consultants in communicable disease control and microbial water pollution students. Focuses on the microorganisms of most significance to public health, including E. coli, cryptosporidium, and enterovirus Highlights the basic microbiology, clinical features, survival in the environment, and gives a risk assessment for each pathogen Contains new material on antimicrobial resistance and biofilms Covers drinking water and both marine and freshwater recreational bathing waters

Verocytotoxigenic E. Coli

Verocytotoxigenic E. Coli
  • Author : Geraldine Duffy,Patricia Garvey,David A. McDowell
  • Publisher :Unknown
  • Release Date :2008-06-02
  • Total pages :457
  • ISBN : 9780470384879
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Summary : Verocytotxin producing Escherichia coli (VTEC), and in particular, strains of serogroup o157, have emerged as significant pathogens causing a range of severe and potentially fatal illnesses. The European Union has recognised the threat posed by E. coli O157:H7 and the need to devise control strategies based on an understanding of VTEC pathogenicity, transmission, survival and growth. It also acknowledges the imortance of informing farmers, veterinarians, food producers and health authorities so that each of these groups can act appropriately to reduce the overall hazards posed by these organisms. To contribute to the development and dissemination of effect control strategies, the European Commission funded a Concerted Action Project "A European study on animal, food, and biomedical aspects of verocytotoxigenic E. coli including serotype O157:H7, an emerging pathogen" (CT98-3935) within the Agriculture and Agro-industry Framework IV Research Programme (1998-2001). This book, compiled under the auspices of the above project, integrates contributions from project participants and invited contributor, to provide a comprehensive overview of the current state of research on VTEC. It will be invaluable to current workers in this area, and those seeking an effective introduction to research on this important pathogen

Pathogenic Escherichia Coli in Latin America

Pathogenic Escherichia Coli in Latin America
  • Author : Alfredo G. Torres
  • Publisher :Unknown
  • Release Date :2010
  • Total pages :264
  • ISBN : 9781608051922
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Summary : Pathogenic Escherichia coli are known to be a common cause of diarrheal disease - a common cause of frequently occurring bacterial infections in children and adults in developing countries. It poses a significant problem in Latin America. Pathogenic Escherichia coli in Latin America presents current information on understanding pathogenic E. coli in Latin America and outlines prospects for future research in this region. It features a unique, comprehensive analysis of the most common categories of E. coli associated with diarrheal illness in Latin America. The aim of this book is to help epide.

Regulation of Gene Expression in Escherichia coli

Regulation of Gene Expression in Escherichia coli
  • Author : E. C. C. Lin,A. Simon Lynch
  • Publisher :Unknown
  • Release Date :2012-11-26
  • Total pages :592
  • ISBN : 1468486039
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Summary :

Escherichia Coli

Escherichia Coli
  • Author : Max Sussman,Professor of Bacteriology Department of Microbiology Max Sussman
  • Publisher :Unknown
  • Release Date :1997-03-27
  • Total pages :639
  • ISBN : 0521453615
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Summary : This comprehensive compilation, written by an authoritative team of international contributors, surveys the role E. coli plays in health and disease. First, the diseases in humans and animals attributable to E. coli are described in general terms, including a discussion of the part it plays in the normal flora of humans and animals. The next section is devoted to each of the recognized virulence factors and mechanisms, including capsules, adhesins, hemolysins, endotoxins and exotoxins, and iron scavenging. The third section covers in detail various diseases and their mechanisms. The final section addresses the host responses to infection and the design of vaccines.

Foodborne Infections and Intoxications

Foodborne Infections and Intoxications
  • Author : Teresa Estrada-Garcia,Kim Hodges,Gail A. Hecht,Phillip I. Tarr
  • Publisher :Unknown
  • Release Date :2013-03-06
  • Total pages :568
  • ISBN : 9780128073582
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Summary : Escherichia coli are leading causes of diarrhea in children from less developed areas of the world and in travelers from industrialized countries visiting these regions. They are increasingly recognized as pathogens in high income countries, where the mode of transmission is frequently via food and waterborne vehicles. Based on their pathogenic phenotypes and the diseases that they cause, diarrheagenic E. coli have been classified into 6 groups: enteropathogenic (EPEC), enterotoxigenic (ETEC), enteroinvasive (EIEC), enteroaggregative (EAEC), diffusely adherent (DAEC), and Shiga toxin producing (STEC) (this last group is also termed enterohemorrhagic (EHEC)). The pathogenic mechanisms by which these groups cause diarrhea are often shared, such as the type 3 secretion system found in EPEC and EHEC, and group-specific, such as the production of Shiga toxins. Although their public health importance is large, the diagnosis of diarrheagenic E. coli in patients and populations is still largely limited to research laboratories. Hence, our knowledge of the spectrum of diseases and syndromes that they cause is quite limited. Also, because we cannot readily identify infected patients, there are many difficulties defining modes of acquisition, prevention and treatment strategies, and estimating the burden of infectious sequelae. These infections pose many challenges, and progress will not occur until we improve our diagnostic capabilities for these agents.

Escherichia coli

Escherichia coli
  • Author : Victor A. Garcia-Angulo,Mauricio J. Farfan,Alfredo G. Torres
  • Publisher :Unknown
  • Release Date :2013-06-12
  • Total pages :612
  • ISBN : 9780128061855
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Summary : In addition to the well-established and extensively studied categories of pathogenic E. coli, there are other groups of E. coli associated with diarrheal and/or inflammatory bowel diseases that have not been thoroughly characterized or which are considered newly emergent pathogens. This chapter focuses on three representatives of these groups of pathogenic E. coli and the current progress understanding their role in pathogenesis. Diffusely adherent E. coli (DAEC) are a collection of isolates that colonize the small bowel, considered potentially diarrheagenic, and that can cause childhood diarrhea. Adherent and invasive E. coli (AIEC) are a group of mucosa-associated bacteria with invasive properties in Crohn’s disease patients and can survive and replicate extensively in macrophages. Finally, E. coli O104:H4, a hybrid Shiga toxin-producing enteroaggregative E. coli, which caused a large outbreak in Europe in 2011, displays a unique combination of virulence traits resulting in the development of hemolytic uremic syndrome in an unusually large proportion of infected patients. This chapter summarizes recent progress in understanding the pathogenesis and the clinical outcome of these types of E. coli infections.

The Universe of Escherichia coli

The Universe of Escherichia coli
  • Author : Marjanca Starčič Erjavec
  • Publisher :Unknown
  • Release Date :2019-09-18
  • Total pages :148
  • ISBN : 9781838811525
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Summary : The title of the book "The Universe of Escherichia coli" aims to present and emphasize the huge diversity of this bacterial species and our efforts to prevent the E. coli infections. As it is part of the gut microbiota, E. coli is a well-known commensal species, and probiotic E. coli strains are successfully used for improving host's health. Also many "workhorse" E. coli strain exist that are employed in laboratory and biotechnology settings. But certain E. coli strains can cause intestinal and also extraintestinal infections at many anatomical sites. Therefore many efforts are undertaken to prevent E. coli infections, among them food safety, vaccines, but also new antimicrobial agents are searched for.

Escherichia coli

Escherichia coli
  • Author : David M. Gordon
  • Publisher :Unknown
  • Release Date :2013-06-12
  • Total pages :612
  • ISBN : 9780128061756
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Summary : Although E. coli is primarily a commensal of mammals, and to a lesser extent birds, it can be isolated from a variety of host species as well as soil, sediments, and water. It has long been recognized that E. coli exhibits quite extensive substructuring and that the relative abundance of the most common phylo-groups varies with respect to host age and sex, host species, as well as geographical location. Strains belonging to some phylo-groups are much more frequently encountered in water samples than strains belonging to other phylo-groups. The extent to which strain survival in the external environment has determined the evolutionary origins of the various diarrheal pathotypes is unknown. There is a growing body of evidence that indicates commensal E. coli, like the diarrheal pathotypes, exhibits at some tissue specificity within the gastrointestinal tract. However, there is little evidence to suggest that commensal E. coli exhibit extensive host specificity as is the case with many of the diarrheal pathotypes.

E.coli

E.coli
  • Author : Stephen Palmer,Sharon Parry
  • Publisher :Unknown
  • Release Date :2003-08-29
  • Total pages :192
  • ISBN : 9781134562909
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Summary : The control of E.coli 0157 is at the heart of the environmental health practitioner's professional agenda. This book is aimed at health professionals who need to be fully informed about the sources and effects of the organism in order to provide advice and enforce legislation at local level as well as providing non specialist professionals with a practical introduction to the terminology, methods and issues surrounding the diagnosis and control of E.coli.

E. Coli

E. Coli
  • Author : Dana Philpott,Frank Ebel
  • Publisher :Unknown
  • Release Date :2003
  • Total pages :368
  • ISBN : 9781592593163
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Summary : Leading experimentalists detail the key protocols for the diagnosis and study of the pathogenesis of Shiga toxin-producing Escherichia coli (STEC) and its isolated cytotoxin (Stx). Described in step-by-step detail, these readily reproducible techniques range from those for the diagnosis and detection of STEC bacteria in patient and animal samples, to those for studying the cellular microbiology of STEC infections, especially host-pathogen interactions and the hemolysin of STEC.

E. coli in Motion

E. coli in Motion
  • Author : Howard C. Berg
  • Publisher :Unknown
  • Release Date :2008-01-11
  • Total pages :134
  • ISBN : 9780387216386
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Summary : Escherichia coli, commonly referred to as E. coli, has been the organism of choice for molecular genetics for decades. Its machinery and mobile behavior is one of the most fascinating topics for cell scientists. Scientists and engineers, not trained in microbiology, and who would like to learn more about living machines, can see it as a unique example. This cross-disciplinary monograph covers more than thirty years of research and is accessible to graduate students and scientists alike.