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Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components

Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components
  • Author : Mahendra Rai,Kateryna Kon
  • Publisher :Unknown
  • Release Date :2013-05-24
  • Total pages :296
  • ISBN : 9780124017085
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Summary : Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and their Components offers scientists a single source aimed at fighting specific multidrug-resistant (MDR) microorganisms such as bacteria, protozoans, viruses and fungi using natural products. This essential reference discusses herbal extracts and essential oils used or under investigation to treat MDR infections, as well as those containing antimicrobial activity that could be of potential interest in future studies against MDR microorganisms. The need to combat multidrug-resistant microorganisms is an urgent one and this book provides important coverage of mechanism of action, the advantages and disadvantages of using herbal extracts, essential oils and their components and more to aid researchers in effective antimicrobial drug discovery Addresses the need to develop safe and effective approaches to coping with resistance to all classes of antimicrobial drugs Provides readers with current evidence-based content aimed at using herbal extracts and essential oils in antimicrobial drug development Includes chapters devoted to the activity of herbal products against herpes, AIDS, tuberculosis, drug-resistant cancer cells and more

Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components

Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components
  • Author : Kateryna Volodymyrivna Kon,Mahendra Kumar Rai
  • Publisher :Unknown
  • Release Date :2013-05-24
  • Total pages :296
  • ISBN : 9780128066812
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Summary : High prevalence of multidrug-resistant microorganisms in the etiologic structure of different infectious processes significantly decreases the effectiveness of the treatment and enhances the probability of an unfavorable outcome from the infection. Combinations between antibiotics and other antimicrobial agents represent one of the most promising approaches for combating multidrug-resistant bacteria. A high therapeutic potential exists for combinations of antibiotics and natural antimicrobial substances with complex mechanisms of action and multiple healing properties, such as plant essential oils. The purpose of the present chapter is to review published studies on antibiotic-essential oil combinations and discuss the prospects for future studies. In general, many studies have shown the potential for essential oils to act synergistically with antibiotics in vitro. The main proposed mechanism of this beneficial effect is through inhibition of efflux pumps by some essential oils, which restores the activity of the antibiotic. Future efforts should be directed into further studies of antibiotic-essential oil combinations against multidrug-resistant bacteria, with an emphasis on understanding the mechanisms of the produced effect. Combinations of essential oils with different types of antimicrobial agents, such as bacteriophages, nanoparticles, and quorum-sensing inhibitors, require greater attention and are worthy of future investigations.

Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components

Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components
  • Author : Lyndy McGaw
  • Publisher :Unknown
  • Release Date :2013-05-24
  • Total pages :296
  • ISBN : 9780128066843
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Summary : Many bacterial diseases affect animals, causing important economic losses in livestock. Subtherapeutic antibiotic use in production animals as antibiotic growth promoters has been implicated as a causative factor in the development of resistance of bacterial pathogens toward several classes of antimicrobials, some of which are used therapeutically in humans. This has led to the banning of antibiotic growth promoters by the European Union, and such a precedent may be followed in other countries. Alternatives to antibiotic growth promoters are necessary to enable the production of animal protein to keep pace with the expanding world population. One approach is to use plant extracts or essential oils as supplements to provide beneficial effects, including direct antibacterial activity and stimulation of the immune system, or enhancement of ruminal digestion. The risk of resistance developing to a combination of phytochemicals is lower than the risk of resistance against a single antibiotic, and synergistic effects of plant constituents may contribute to the overall activity of the preparation.

Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components

Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components
  • Author : M. Fawzi Mahomoodally,Ameenah Gurib-Fakim
  • Publisher :Unknown
  • Release Date :2013-05-24
  • Total pages :296
  • ISBN : 9780128066867
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Summary : Infectious diseases are responsible for one in every two deaths in many developing countries, but people in sub-Saharan Africa are particularly vulnerable, as poverty is rampant and access to health care is limited. Additionally, the unregulated use of antibiotics in some parts of Africa has led to the emergence of resistance in pathogens. Indeed, one of the biggest pandemics is malaria, which kills millions annually. Currently, artemisinin (effective against chloroquine-resistant Plasmodium) is the only weapon available to fight this pandemic, yet the World Health Organization has reported with concern that some countries in Southeast Asia are beginning to witness resistance to artemisinin. As a consequence, increasing attention is being drawn to botanicals, as they have the potential to provide alternative and complementary therapies, as well as potential leads to address emerging infections and resistance. This chapter will review some medicinal plants from the African Herbal Pharmacopoeia that show promise for containing existing and emerging infectious diseases.

Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components

Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components
  • Author : Victor Kuete
  • Publisher :Unknown
  • Release Date :2013-05-24
  • Total pages :296
  • ISBN : 9780128066744
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Summary : The development of vancomycin resistance by some microbial strains has made the treatment of some infections more difficult and, in many cases, impossible. Although the search for new drugs against vancomycin-resistant organisms has been very successful, resistance can arise against many of these compounds. Natural products are an invaluable source of a diversity of biologically active compounds for addressing the challenges facing drug development initiatives to combat vancomycin-resistant enterococcal infections. Despite the fact that scientific data on plant metabolites active against vancomycin-resistant enterococci remain scarce, some compounds (including terpenoids and phenolics) have been reported to have inhibitory effects at various levels. This chapter describes the state of the art of research into plant bioactive metabolites against vancomycin-resistant enterococci, highlighting the hit compounds.

Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components

Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components
  • Author : Adil M. Allahverdiyev,Melahat Bagirova,Serkan Yaman,Rabia Cakir Koc,Emrah Sefik Abamor,Sezen Canim Ates,Serap Yesilkir Baydar,Serhat Elcicek,Olga Nehir Oztel
  • Publisher :Unknown
  • Release Date :2013-05-24
  • Total pages :296
  • ISBN : 9780128066881
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Summary : Herpes simplex virus (HSV) infections comprise one of the most important health problems worldwide. HSV-1 and HSV-2 that are the types most frequently seen in disease, manifested by sores and blisters on the mouth, tongue, skin, and genitals of infected individuals. Moreover, herpetic infections can reach life-threatening levels; for instance, HSV-2 prevalence has increased greatly in human immunodeficiency virus-positive patients. This indicates that the herpetic infection could be a major cause of morbidity in immunosuppressed patients. Unfortunately, resistance against antiherpetic drugs has recently been reported. Therefore there is an immediate need to search for new antiviral agents in order to cope with HSV infections. Recently, it has been demonstrated that traditional medicinal plants have strong antiviral activity and some are already being used in the treatment of viral infections, including herpes simplex infections. Accordingly, this chapter aims to present published information on various herbal compounds, investigate the antiherpetic effectiveness of these compounds, and determine the potential of plants as herpetic treatments in the future.

Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components

Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components
  • Author : M.L. Faleiro,M.G. Miguel
  • Publisher :Unknown
  • Release Date :2013-05-24
  • Total pages :296
  • ISBN : 9780128066775
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Summary : Aromatic and medicinal plants, through their secondary metabolism, provide a complex mixture of volatile molecules known as essential oils. These volatile molecules exert antibacterial activity that has been used in folk medicine for centuries. During the last few decades, the emergence of antibacterial resistance has forced us to search for new and efficient antimicrobial agents. The significant number of studies on the use of essential oils and their components against multidrug-resistant bacteria, such as Acinetobacter baumannii, methicillin-resistant Staphylococcus aureus, Mycobacterium tuberculosis, and Pseudomonas aeruginosa show the exceptional potential of these natural products to curb the development of antibacterial resistance. Moreover, the use of essential oils and their components in combination with antibiotics may increase bacterial susceptibility, thus limiting resistance.

Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components

Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components
  • Author : Valerie Edwards-Jones
  • Publisher :Unknown
  • Release Date :2013-05-24
  • Total pages :296
  • ISBN : 9780128066720
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Summary : The global increase in antimicrobial resistance has led to renewed interest in alternative antimicrobial treatment strategies. Research is being done into a wide range of possible treatment regimens, including phage therapy, novel vaccines, and novel peptides, to name a few. Many microbiologists continue to lobby their governments to ensure that the available antibiotics are retained for the treatment of serious infections and their inappropriate use is stopped. In addition, large pharmaceutical companies are being encouraged to develop new treatments for the future. Much research now focuses on medicinal plants and essential oils. These and other alternative approaches are outlined in this chapter.

Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components

Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components
  • Author : Ali Parsaeimehr,Elmira Sargsyan,Amir Reza Jassbi
  • Publisher :Unknown
  • Release Date :2013-05-24
  • Total pages :296
  • ISBN : 9780128066836
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Summary : In today’s world, multidrug resistance appears to be one of the major health problems; however, screening, discovering and presenting novel effectual phytochemicals from medicinal plants have provided a promising outlook. Phytomedicines have been used for treating diseases and infections since time immemorial, but identifying new phytochemicals and effectual treatment strategies are essential in the fight against multidrug-resistant bacteria. Currently, isolated compounds such as α-mangostin, carnosic acid, epigallocatechin gallate, linalool, myricetin, novoimanin, α-terpineol, and totarol, have exhibited synergistic activity with antibiotics against resistant bacteria. This chapter presents information on multidrug-resistant Gram-negative bacteria and the use of herbal extracts against them.

Antibiotic Resistance

Antibiotic Resistance
  • Author : Kateryna Kon,Mahendra Rai
  • Publisher :Unknown
  • Release Date :2016-06-14
  • Total pages :436
  • ISBN : 9780128036686
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Summary : Antibiotic Resistance: Mechanisms and New Antimicrobial Approaches discusses up-to-date knowledge in mechanisms of antibiotic resistance and all recent advances in fighting microbial resistance such as the applications of nanotechnology, plant products, bacteriophages, marine products, algae, insect-derived products, and other alternative methods that can be applied to fight bacterial infections. Understanding fundamental mechanisms of antibiotic resistance is a key step in the discovery of effective methods to cope with resistance. This book also discusses methods used to fight antibiotic-resistant infection based on a deep understanding of the mechanisms involved in the development of the resistance. Discusses methods used to fight antibiotic-resistant infection based on a deep understanding of mechanisms involved in the development of the resistance Provides information on modern methods used to fight antibiotic resistance Covers a wide range of alternative methods to fight bacterial resistance, offering the most complete information available Discusses both newly emerging trends and traditionally applied methods to fight antibiotic resistant infections in light of recent scientific developments Offers the most up-to-date information in fighting antibiotic resistance Includes involvement of contributors all across the world, presenting questions of interest to readers of both developed and developing countries

Essential Chemistry for Aromatherapy E-Book

Essential Chemistry for Aromatherapy E-Book
  • Author : Sue Clarke
  • Publisher :Unknown
  • Release Date :2009-02-10
  • Total pages :320
  • ISBN : 9780702037054
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Summary : This new edition of ESSENTIAL CHEMISTRY FOR SAFE AROMATHERAPY provides an accessible account of the key theoretical aspects of chemistry and their application into the safe practice of aromatherapy. For readers with a limited science background, this book offers a clear and concisely written guide to essential information in chemistry. For practitioners, the book applies chemistry to the practical and therapeutic use of essential oils, and leads to a better understanding of composition, properties and technical data related to essential oils. Takes the fear and mystery out of chemistry for aromatherapy students! Presents crucial information in a clear and easily-digestible format, highlighting key points all along Allows professional aromatherapists to practice with greater confidence, safety and skill, and to extend the range of their practice through a clearer understanding of chemical properties of essential oils. Covers the scope of what is taught at major aromatherapy teaching centres, and structures the material to make sure each chapter provides the reader with a rounded understanding of the topic covered. A glossary is included for easy reference. Fully-updated throughout Chapter 5, Analytical Techniques completely brought up to date Chapter 6 Oil Profiles updated to include those used in current training New section entitled ‘In perspectives’ covers risks and benefits, interpretation of clinical trials and experimental data, use of essential oils in aromatherapy and functional groups in relation to therapeutic properties

Natural Antimicrobial Agents

Natural Antimicrobial Agents
  • Author : Jean-Michel Mérillon,Céline Riviere
  • Publisher :Unknown
  • Release Date :2018-02-08
  • Total pages :337
  • ISBN : 9783319670454
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Summary : Documenting the latest research in the field of different pathogenic organisms, this book presents the current scenario about promising antimicrobials in the following areas: Part I. Plants as source of antibacterials, Part II. Naturally occurring antifungal natural products, Part III. Antiparasitic natural products, Part IV. Antiviral natural products. Renowned scientists from the globe have been selected as authors to contribute chapters. Use of plants for various ailments is as old as human civilization and continuous efforts are being made to improve medicinal plants or to product their bioactive secondary metabolites in high amounts through various technologies. About 200,000 natural products of plant origin are known and many more are being identified from higher plants and micro-organisms. Some plants based drugs are used since centuries and there is no alternative medicine for many such drugs as cardiac glycosides. Drug discovery from medicinal plants or marine micro-organisms continues to provide an important source of new drug leads. Research on new antibacterials represents a real and timely challenge of this century, particularly for the treatment of infections caused by clinical isolates that show multidrug resistance. The main microorganisms involved in the resistance process have been identified and given the acronym ESKAPE for Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumanii, Pseudomonas aeruginosa and Enterobacteriaceae. Multidrug resistant Mycobacterium tuberculosis including highly drug-resistant strains (XDR-TB) has also emerged as one of the most important clinical challenges of this century. Plants of diverse taxa and marine micro-organisms are rich source of these antimicrobials. An attempt has been made to compile the recent information about natural sources of antibacterials and their sustainable utilization. Increased panic of these pathogens warrants a growing demand for research to undertake the threat of multidrug resistance. The search for new antifungal, antiparasitic and antiviral natural products is far from devoid of interest. According to the WHO report in 2013, malaria still represents some 207 million cases worldwide and more than 3 billion of people are still exposed to this risk. Similarly, about 350 million people are considered at risk of contracting leishmaniasis. The fight against some viruses also requires that the research on natural products continue. For example, even if an antiretroviral with direct action was recently approved in Europe in 2013, its high cost does not allow to offer it to an exposed population in countries where the cost of drugs remains a problem for a large part of the population. These books are useful to researchers and students in microbiology, biotechnology, pharmacology, chemistry and biology as well as medical professionals.

Pathogenicity and Drug Resistance of Human Pathogens

Pathogenicity and Drug Resistance of Human Pathogens
  • Author : Saif Hameed,Zeeshan Fatima
  • Publisher :Unknown
  • Release Date :2020-01-23
  • Total pages :404
  • ISBN : 9789813294493
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Summary : The book comprehensively discusses the mechanisms of pathogenesis and drug resistance; current diagnostics landscape of four key human pathogens; bacterial, fungal, protozoans and viral which are the causes of major infectious diseases. It also assesses the emerging technologies for the detection and quantification of these pathogens. Further, it discusses the novel opportunities to fight against these infectious diseases and to identify pertinent drug targets with novel methodologies. It also reviews the current and future insights into the control, elimination, and eradication of these infectious diseases. Importantly, the book discusses the epidemiological characteristics and various challenges in combating Ebola and Influenza diseases. Finally, the book highlights the growing role of nanotechnology and bioinformatics resources for combating the infectious diseases. In summary, the book provides the mechanistic insight of the pathogenicity, drug-resistance, therapeutic strategies and identification of the novel drug targets of Mycobacterium tuberculosis, Plasmodium, Candida, Hepatitis C and emerging viral infections.

Toxicological Survey of African Medicinal Plants

Toxicological Survey of African Medicinal Plants
  • Author : Victor Kuete
  • Publisher :Unknown
  • Release Date :2014-05-30
  • Total pages :744
  • ISBN : 9780128004753
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Summary : Toxicological Survey of African Medicinal Plants provides a detailed overview of toxicological studies relating to traditionally used medicinal plants in Africa, with special emphasis on the methodologies and tools used for data collection and interpretation. The book considers the physical parameters of these plants and their effect upon various areas of the body and human health, including chapters dedicated to genotoxicity, hepatotoxicity, nephrotoxicity, cardiotoxicity, neurotoxicity, and specific organs and systems. Following this discussion of the effects of medicinal plants is a critical review of the guidelines and methods in use for toxicological research as well as the state of toxicology studies in Africa. With up-to-date research provided by a team of experts, Toxicological Survey of African Medicinal Plants is an invaluable resource for researchers and students involved in pharmacology, toxicology, phytochemistry, medicine, pharmacognosy, and pharmaceutical biology. Offers a critical review of the methods used in toxicological survey of medicinal plants Provides up-to-date toxicological data on African medicinal plants and families Serves as a resource tool for students and scientists in the various areas of toxicology

Herbal Contraindications and Drug Interactions

Herbal Contraindications and Drug Interactions
  • Author : Francis Brinker
  • Publisher :Unknown
  • Release Date :2010
  • Total pages :598
  • ISBN : 1888483148
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Summary : This book's first edition (1997) was the first of its kind in addressing herbal interactions with drugs. This 4th edition keeps current with research findings and scrupulously distinguishes between what is known through (1) empirical clinical observations such as case reports, (2) data obtained from modern clinical human studies, (3) different types of laboratory research on animals and with tissues and cells. Over 2700 medical and scientific sources are cited to document these findings. In addition, the type of preparation studied is described to emphasize differences between preparations from the same herb, along with dosage size and duration. Conflicting results are utilized to put these issues in context. This fourth edition further highlights those combinations of herbal preparations with drugs shown to beneficially enhance therapeutic activity or reduce adverse effects, identified for 98 of the 321 herbs listed in the main text. In addition, extensive appendices organize information on these 321 and additional herbal remedies into categories addressing specific cautions, interactions with particular types of drugs, precautions for mothers, infants and children, drug interactions with vitamins and minerals, and advantageous combinations with medicines used for inflammations, infections, cancer, and for addressing substance abuse. The appendix sections addressing herbal influences on drug absorption and metabolism involving transport proteins, cytochrome P450 isoenzymes, and conjugating enzymes are the most extensive compilations available anywhere.

Microbiology for Surgical Infections

Microbiology for Surgical Infections
  • Author : Kateryna Kon,Mahendra Rai
  • Publisher :Unknown
  • Release Date :2014-03-18
  • Total pages :324
  • ISBN : 9780124116429
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Summary : Microbiology for Surgical Infections: Diagnosis, Prognosis and Treatment explores current trends in etiology and antibiotic resistance of pathogens responsible for devastating and complex surgical infections. Clinicians and researchers report the most recent advances in diagnostic approaches to bacterial and non-bacterial surgical infections, including invasive fungal infections. Current guidelines for prophylaxis of community-acquired and nosocomial infections, complications in surgery, and improvement of diagnosis and treatment of these devastating surgical infections are also discussed. The work gives specific attention to intra-abdominal and wound infections, as well as infections in cardiac surgery and neurosurgery. Taken together, these explorations inform the work of specialists in different surgical arenas, as well as those working in microbiology. Microbiology for Surgical Infections provides a resource to those working to improve outcomes in this complicated arena by discussing prospects for future study and identifying targets for future research. Provides a multi-dimensional view of myriad topics pertinent to surgical infections, including questions of etiology, pathogenesis, host-microbial interactions, diagnosis, prognosis, treatment and prophylaxis Delivers cutting-edge commentary from eminent surgeons, microbiologists, and infectious disease specialists, with global contributions from both the developed and developing worlds Presents comprehensive research informed by the most recent technological and scientific advances in the field

Clinical Aromatherapy - E-Book

Clinical Aromatherapy - E-Book
  • Author : Jane Buckle
  • Publisher :Unknown
  • Release Date :2014-11-14
  • Total pages :432
  • ISBN : 9780702064869
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Summary : Enhance patient care with the help of aromatherapy! Clinical Aromatherapy: Essential Oils in Healthcare is the first and only peer-reviewed clinical aromatherapy book in the world and features a foreword by Dr. Oz. Each chapter is written by a PhD nurse with post-doctoral training in research and then peer reviewed by named experts in their field. This clinical text is the must-have resource for learning how to effectively incorporate aromatherapy into clinical practice. This new third edition takes a holistic approach as it examines key facts and topical issues in aromatherapy practice and applies them within a variety of contexts and conditions. This edition also features updated information on aromatherapy treatments, aromatherapy organizations, essential oil providers, and more to ensure you are fully equipped to provide patients with the best complementary therapy available. Expert peer-reviewed information spans the entire book. All chapters have been written by a PhD nurse with post-doctoral training in research and then peer reviewed by named experts in their field. Introduction to the principles and practice of aromatherapy covers contraindications, toxicity, safe applications, and more. Descriptions of real-world applications illustrate how aromatherapy works in various clinical specialties. Coverage of aromatherapy in psychiatric nursing provides important information on depression, psychosis, bipolar, compulsive addictive, addiction and withdrawal. In-depth clinical section deals with the management of common problems, such as infection and pain, that may frequently be encountered on the job. Examples of specific oils in specific treatments helps readers directly apply book content to everyday practice. Evidence-based content draws from thousands of references. NEW! First and only totally peer-reviewed, evidence-based, clinical aromatherapy book in the world. NEW Chapter on integrative Healthcare documenting how clinical aromatherapy has been integrated into hospitals and healthcare in USA, UK and elsewhere. NEW Chapter on the M Technique: the highly successful method of gentle structured touch pioneered by Jane Buckle that is used in hospitals worldwide. All chapters updated with substantial additional references and tables.

Antibacterial Drug Discovery to Combat MDR

Antibacterial Drug Discovery to Combat MDR
  • Author : Iqbal Ahmad,Shamim Ahmad,Kendra P. Rumbaugh
  • Publisher :Unknown
  • Release Date :2019-11-09
  • Total pages :680
  • ISBN : 9789811398711
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Summary : This book compiles the latest information in the field of antibacterial discovery, especially with regard to the looming threat of multi-drug resistance. The respective chapters highlight the discovery of new antibacterial and anti-infective compounds derived from microbes, plants, and other natural sources. The potential applications of nanotechnology to the fields of antibacterial discovery and drug delivery are also discussed, and one section of the book is dedicated to the use of computational tools and metagenomics in antibiotic drug discovery. Techniques for efficient drug delivery are also covered. The book provides a comprehensive overview of the progress made in both antibacterial discovery and delivery, making it a valuable resource for academic researchers, as well as those working in the pharmaceutical industry.

Dietary Phytochemicals and Microbes

Dietary Phytochemicals and Microbes
  • Author : Amlan K. Patra
  • Publisher :Unknown
  • Release Date :2012-03-21
  • Total pages :400
  • ISBN : 9789400739260
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Summary : Humans have utilized the bioactive principles of different plants for various beneficial physiological properties including antimicrobial properties for many centuries. However, interests of using medicinal plants declined in the 20th century with the availability of effective synthetic antimicrobial drugs. The development of microbial resistance to various drugs has accelerated research interests towards the use of phytochemicals as alternatives to synthetic drugs in the recent years. This book presents an comprehensive reviews on the antimicrobial and antiviral properties of numerous recently reported phytochemicals, and their mechanisms of antimicrobial actions. Some of the chapters have critically discussed the beneficial and adverse effects of antibacterial, and stimulatory activities of dietary phytochemicals on rumen microbial populations, and gut microbial populations of humans and animals. Microbial adaptation and resistance of microbes to phytochemicals has also been highlighted. On the applied apects, the use of phytochemicals against drug resistance microbes, to treat microbial diseases, for food preservation, to inhibit methanogenic archaea in the rumen, and to modulate lipid biohydrogenating microbial populations to increase conjugated linoleic acids in animal-derived foods have been presented in different chapters.

Biotechnology and Production of Anti-Cancer Compounds

Biotechnology and Production of Anti-Cancer Compounds
  • Author : Sonia Malik
  • Publisher :Unknown
  • Release Date :2017-04-21
  • Total pages :328
  • ISBN : 9783319538808
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Summary : This book discusses cancers and the resurgence of public interest in plant-based and herbal drugs. It also describes ways of obtaining anti-cancer drugs from plants and improving their production using biotechnological techniques. It presents methods such as cell culture, shoot and root culture, hairy root culture, purification of plant raw materials, genetic engineering, optimization of culture conditions as well as metabolic engineering with examples of successes like taxol, shikonin, ingenol mebutate and podophylotoxin. In addition, it describes the applications and limitations of large-scale production of anti-cancer compounds using biotechnological means. Lastly, it discusses future economical and eco-friendly strategies for obtaining anti-cancer compounds using biotechnology.

Phytochemicals

Phytochemicals
  • Author : Venketeshwer Rao,Leticia Rao
  • Publisher :Unknown
  • Release Date :2015-09-30
  • Total pages :350
  • ISBN : 9789535121701
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Summary : Global dietary recommendations emphasize the consumption of plant-based foods for the prevention and management of chronic diseases. Plants contain many biologically active compounds referred to as phytochemicals or functional ingredients. These compounds play an important role in human health. Prior to establishing the safety and health benefits of these compounds, they must first be isolated, purified, and their physico-chemical properties established. Once identified, their mechanisms of actions are studied. The chapters are arranged in the order from isolation, purification and identification to in vivo and clinical studies, there by covering not only the analytical procedures used but also their nutraceutical and therapeutic properties.