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Index Medicus

Index Medicus
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2004
  • Total pages :229
  • ISBN : OSU:32436011091848
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Summary :

Neurosciences at the Postgenomic Era

Neurosciences at the Postgenomic Era
  • Author : Jacques Mallet
  • Publisher :Unknown
  • Release Date :2012-12-06
  • Total pages :189
  • ISBN : 9783642555435
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Summary : In this new volume in the series Research and Perspectives in Neurosciences the authors have presented and discussed their findings in the fields of speech and language disorders, X-linked mental retardation, gene therapy in the CNS, memory and learning disorders and other fields.

RTD Info

RTD Info
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2002-11
  • Total pages :229
  • ISBN : NYPL:33433078187006
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Summary :

Spirochete Biology: The Post Genomic Era

Spirochete Biology: The Post Genomic Era
  • Author : Ben Adler
  • Publisher :Unknown
  • Release Date :2018-08-21
  • Total pages :295
  • ISBN : 9783319896380
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Summary : Spirochetes comprise a fascinating group of bacteria. Although diverse in terms of their habitat, ecology and infectivity for vertebrate and non-vertebrate hosts, they are often considered together because of their similar cellular morphologies. This volume brings together an international group of experts to provide essential insights into spirochete biology, with an emphasis on recent advances made possible by the availability of genome sequences. As such, it offers a valuable resource for microbiologists and other scientists with an interest in spirochete biology.

Metabolic Engineering in the Post Genomic Era

Metabolic Engineering in the Post Genomic Era
  • Author : Boris N. Kholodenko,Hans V. Westerhoff
  • Publisher :Unknown
  • Release Date :2004
  • Total pages :456
  • ISBN : 0954523229
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Summary : The Horizon Scientific Press titles focus on high-level microbiology and molecular biology topics. Written by internationally renowned and highly respected leaders in the field, titles in this series comprise of review manuals, practical manuals, and reference texts for research scientists, bioscience professionals and graduate students. Engineering living cells continues to pose immense challenges to the researcher. In fact many bioengineers have only just started to appreciate the full extent of the hierarchical control used by living systems: upon attempts to increase the activity of a "rate-limiting" step, the multiple feedbacks at the metabolic, signaling and genetic levels result in the rate limiting step shifting to elsewhere in that pathway or even to elsewhere in the whole organism. The advent of full-force genomics should enable preventing this response, however, it has been difficult for researchers to know where to turn for guidance. This book aims to help the reader understand and deal with the plasticity of living cell factories and to turn the plasticity into the desired rather than the adverse direction. The book brings together all the recent, most important breakthroughs in this exciting field: Internationally renowned key scientists have reviewed each topic in detail. In the Introduction, the editors give an overview of new approaches and spell out what the engineer and the industry may now really begin to aim for; they even adapt the definition of metabolic engineering to befit the post-genomics era. Other topics included are: the experimental approaches necessary to understand cellular regulation at all of its hierarchical levels, including proteomics [Chapter 2], metabolomics [Chapter 3] and fluxomics [Chapter 4]; new tools that help metabolic engineering [Chapters 5-7]; modeling of living cells, e.g. finding metabolic pathways [Chapter 8] and comparing the actual and predicted use of these in living organisms such as E. coli and Corynebacteria [Chapters 9, 10]; the optimization of cell factories as production organisms (e.g., use of whole cell models, silicon cells, and coordinate manipulation of multiple genes [Chapters 12-15]). A chapter on future perspectives directs further developments of the field in the near future. Metabolic Engineering in the Post Genomic Erais an essential reading for everyone with an interest in engineering living cells including: Metabolic egnineers, bioengineers, biotechnologists, molecular biologists, and pharmaceutical and biotechnology companies.

ASM News

ASM News
  • Author : American Society for Microbiology
  • Publisher :Unknown
  • Release Date :1999
  • Total pages :229
  • ISBN : UCLA:L0078736550
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Summary :

The Science and Applications of Microbial Genomics

The Science and Applications of Microbial Genomics
  • Author : Institute of Medicine,Board on Global Health,Forum on Microbial Threats
  • Publisher :Unknown
  • Release Date :2013-05-02
  • Total pages :428
  • ISBN : 9780309268196
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Summary : Over the past several decades, new scientific tools and approaches for detecting microbial species have dramatically enhanced our appreciation of the diversity and abundance of the microbiota and its dynamic interactions with the environments within which these microorganisms reside. The first bacterial genome was sequenced in 1995 and took more than 13 months of work to complete. Today, a microorganism's entire genome can be sequenced in a few days. Much as our view of the cosmos was forever altered in the 17th century with the invention of the telescope, these genomic technologies, and the observations derived from them, have fundamentally transformed our appreciation of the microbial world around us. On June 12 and 13, 2012, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to discuss the scientific tools and approaches being used for detecting and characterizing microbial species, and the roles of microbial genomics and metagenomics to better understand the culturable and unculturable microbial world around us. Through invited presentations and discussions, participants examined the use of microbial genomics to explore the diversity, evolution, and adaptation of microorganisms in a wide variety of environments; the molecular mechanisms of disease emergence and epidemiology; and the ways that genomic technologies are being applied to disease outbreak trace back and microbial surveillance. Points that were emphasized by many participants included the need to develop robust standardized sampling protocols, the importance of having the appropriate metadata, data analysis and data management challenges, and information sharing in real time. The Science and Applications of Microbial Genomics summarizes this workshop.

Science

Science
  • Author : John Michels (Journalist)
  • Publisher :Unknown
  • Release Date :2006
  • Total pages :229
  • ISBN : MINN:31951P009971378
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Summary :

The Philosopher's Index

The Philosopher's Index
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2008
  • Total pages :229
  • ISBN : UOM:39015081502976
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Summary : Vols. for 1969- include a section of abstracts.

From Plant Genomics to Plant Biotechnology

From Plant Genomics to Plant Biotechnology
  • Author : Palmiro Poltronieri,Natalija Burbulis,Corrado Fogher
  • Publisher :Unknown
  • Release Date :2013-08-31
  • Total pages :274
  • ISBN : 9781908818478
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Summary : With the appearance of methods for the sequencing of genomes and less expensive next generation sequencing methods, we face rapid advancements of the -omics technologies and plant biology studies: reverse and forward genetics, functional genomics, transcriptomics, proteomics, metabolomics, the movement at distance of effectors and structural biology. From plant genomics to plant biotechnology reviews the recent advancements in the post-genomic era, discussing how different varieties respond to abiotic and biotic stresses, understanding the epigenetic control and epigenetic memory, the roles of non-coding RNAs, applicative uses of RNA silencing and RNA interference in plant physiology and in experimental transgenics and plants modified to specific aims. In the forthcoming years these advancements will support the production of plant varieties better suited to resist biotic and abiotic stresses, for food and non-food applications. This book covers these issues, showing how such technologies are influencing the plant field in sectors such as the selection of plant varieties and plant breeding, selection of optimum agronomic traits, stress-resistant varieties, improvement of plant fitness, improving crop yield, and non-food applications in the knowledge based bio-economy. Discusses a broad range of applications: the examples originate from a variety of sectors (including in field studies, breeding, RNA regulation, pharmaceuticals and biotech) and a variety of scientific areas (such as bioinformatics, -omics sciences, epigenetics, and the agro-industry) Provides a unique perspective on work normally performed 'behind closed doors'. As such, it presents an opportunity for those within the field to learn from each other, and for those on the 'outside' to see how different groups have approached key problems Highlights the criteria used to compare and assess different approaches to solving problems. Shows the thinking process, practical limitations and any other considerations, aiding in the understanding of a deeper approach

Annual report

Annual report
  • Author : South African Institute for Medical Research
  • Publisher :Unknown
  • Release Date :1999
  • Total pages :229
  • ISBN : CHI:54400752
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Summary :

Nature

Nature
  • Author : Sir Norman Lockyer
  • Publisher :Unknown
  • Release Date :2008
  • Total pages :229
  • ISBN : UOM:49015003312338
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Summary :

High-Throughput Protein Production and Purification: Methods and Protocols

High-Throughput Protein Production and Purification: Methods and Protocols
  • Author : Renaud Vincentelli
  • Publisher :Unknown
  • Release Date :2020-07-19
  • Total pages :537
  • ISBN : 1493996266
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Summary :

Genomics, Proteomics and Vaccines

Genomics, Proteomics and Vaccines
  • Author : Guido Grandi
  • Publisher :Unknown
  • Release Date :2004-08-13
  • Total pages :336
  • ISBN : 9780470093924
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Summary : While the sequence of the human genome sequence has hit the headlines, extensive exploitation of this for practical applications is still to come. Genomic and post-genomic technologies applied to viral and bacterial pathogens, which are almost equally important from a scientific perspective, have the potential to be translated into useful products and processes much more rapidly. Genomics, Proteomics and Vaccines introduces the history of vaccinology and discusses how vaccines are expected to evolve in the future. It describes the relevant technologies, including genome sequencing and analysis, DNA microarrays, 2D electrophoresis and 2D chromatography, mass spectrometry and high-throughput protein expression and purification. The book also features examples of the exploitation of genomics and post-genomics in vaccine discovery, and contains useful descriptions of the biology and pathogenesis of clinically important bacterial pathogens. This book should be of interest to all those working in vaccine discovery and development in pharmaceutical and biotechnology companies as well as in academic institutions

Fifth Annual UCSF-Stanford Current Issues in Anatomic Pathology 2002

Fifth Annual UCSF-Stanford Current Issues in Anatomic Pathology 2002
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2002
  • Total pages :229
  • ISBN : UOM:39015069181678
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Summary :

Science, Medicine, and Animals

Science, Medicine, and Animals
  • Author : National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research
  • Publisher :Unknown
  • Release Date :2006-01-19
  • Total pages :23
  • ISBN : 0309181992
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Summary : Science, Medicine, and Animals explains the role that animals play in biomedical research and the ways in which scientists, governments, and citizens have tried to balance the experimental use of animals with a concern for all living creatures. An accompanying Teacher’s Guide is available to help teachers of middle and high school students use Science, Medicine, and Animals in the classroom. As students examine the issues in Science, Medicine, and Animals, they will gain a greater understanding of the goals of biomedical research and the real-world practice of the scientific method in general. Science, Medicine, and Animals and the Teacher’s Guide were written by the Institute for Laboratory Animal Research and published by the National Research Council of the National Academies. The report was reviewed by a committee made up of experts and scholars with diverse perspectives, including members of the U.S. Department of Agriculture, National Institutes of Health, the Humane Society of the United States, and the American Society for the Prevention of Cruelty to Animals. The Teacher’s Guide was reviewed by members of the National Academies’ Teacher Associates Network. Science, Medicine, and Animals is recommended by the National Science Teacher’s Association NSTA Recommends.

From Fundamental Genomics to Systems Biology

From Fundamental Genomics to Systems Biology
  • Author : European Commission. Directorate General for Research
  • Publisher :Unknown
  • Release Date :2008
  • Total pages :508
  • ISBN : STANFORD:36105210629064
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Summary : Accompanying CD-ROM contains text.

Handbook of Molecular and Cellular Methods in Biology and Medicine, Third Edition

Handbook of Molecular and Cellular Methods in Biology and Medicine, Third Edition
  • Author : Leland J. Cseke,Ara Kirakosyan,Peter B. Kaufman,Margaret V. Westfall
  • Publisher :Unknown
  • Release Date :2011-12-12
  • Total pages :735
  • ISBN : 9781420069389
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Summary : Several milestones in biology have been achieved since the first publication of the Handbook of Molecular and Cellular Methods in Biology and Medicine. This is true particularly with respect to genome-level sequencing of higher eukaryotes, the invention of DNA microarray technology, advances in bioinformatics, and the development of RNAi technology. Now in its third edition, this volume provides researchers with an updated tool kit that incorporates conventional as well as modern approaches to tackle biological and medicinal research in the post-genomics era. Significantly revised to address these recent changes, the editors have evaluated, revised, and sometimes replaced protocols with more efficient, more reliable, or simpler ones. The book has also been reorganized with section headings focusing on different biological levels connected to one another, taking into account the central dogma of biology (DNA → RNA → protein → metabolites). The book first explores traditional approaches and then moves to the modern "omics" approaches, including genomics, proteomics, and metabolomics. It also discusses the manipulation of biological systems (including RNAi) and macromolecular analyses, focusing on the use of microscopy. In each chapter, various notes and cautionary considerations are presented for potentially hazardous reagents. Filled with diagrams, tables, and figures to clarify methods, most chapters also contain Troubleshooting Guides indicating problems, possible causes, and solutions that may be incurred in carrying out the procedures. Researchers and scientists who master the techniques in this book are putting themselves at the cutting edge of biological and medicinal research.

Financing Vaccines in the 21st Century

Financing Vaccines in the 21st Century
  • Author : Institute of Medicine,Board on Health Care Services,Committee on the Evaluation of Vaccine Purchase Financing in the United States
  • Publisher :Unknown
  • Release Date :2004-01-10
  • Total pages :264
  • ISBN : 9780309089791
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Summary : The national immunization system has achieved high levels of immunization, particularly for children. However, this system faces difficult challenges for the future. Significant disparities remain in assuring access to recommended vaccines across geographic and demographic populations. These disparities result, in part, from fragmented publicâ€"private financing in which a large number of children and adults face limited access to immunization services. Access for adults lags well behind that of children, and rates of immunizations for those who are especially vulnerable because of chronic health conditions such as diabetes or heart and lung disease, remain low. Financing Vaccines in the 21st Century: Assuring Access and Availability addresses these challenges by proposing new strategies for assuring access to vaccines and sustaining the supply of current and future vaccines. The book recommends changes to the Advisory Committee on Immunization Practices (ACIP)-the entity that currently recommends vaccines-and calls for a series of public meetings, a post-implementation evaluation study, and development of a research agenda to facilitate implementation of the plan.

Institute for Animal Health

Institute for Animal Health
  • Author : Institute for Animal Health (Great Britain)
  • Publisher :Unknown
  • Release Date :2004
  • Total pages :229
  • ISBN : CORNELL:31924101023228
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Summary :

Molecular Genetics of Mycobacteria

Molecular Genetics of Mycobacteria
  • Author : Graham F. Hatfull,William R. Jacobs, Jr.
  • Publisher :Unknown
  • Release Date :2014-09-02
  • Total pages :832
  • ISBN : 9781683673422
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Summary : A comprehensive collection of perspectives by experts in mycobacterial molecular biology Mycobacterium tuberculosis causes one in four avoidable deaths in the developing world and kills more adults than malaria, AIDS, and all tropical diseases combined. Tuberculosis was named a global health emergency by the World Health Organization, a distinction no other disease has received. Although the study of mycobacterial genetics has expanded dramatically, with new investigations into mycobacterial growth, replication, metabolism, physiology, drug susceptibility, and virulence, most of the problems in tuberculosis control that existed in 2000 remain today. Advances in our understanding of mycobacterial genetics have been reflected in exciting recent developments. New diagnostic approaches can identify drug resistance within a few hours, promising new drugs are progressing through the pipeline and into the clinic, and a range of newly developed vaccines are being evaluated. It is an exciting time as the fruits of 30 years of intensive genetic investigation are finally beginning to emerge. Written by leading experts in the field, Molecular Genetics of Mycobacteria, Second Edition, Discusses key areas of current research in mycobacterial genetics Explains the genetics of the physiology, metabolism, and drug sensitivities of M. tuberculosis Presents genetic approaches for manipulating M. tuberculosis This book is an invaluable resource for anyone interested in the molecular genetics and molecular biology of mycobacteria.