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Functionalised Cardiovascular Stents

Functionalised Cardiovascular Stents
  • Author : Gerard Wall,Halina Podbielska,Magdalena Wawrzynska
  • Publisher :Unknown
  • Release Date :2018-02-06
  • Total pages :368
  • ISBN : 9780081004982
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Summary : Cardiovascular disease is a major cause of mortality in the western world and about half of these deaths are caused by coronary artery disease. One of the most commonly used interventions to treat arterial blockages is to deploy an arterial stent to keep the vessel open. Traditionally, some cardiovascular stents have been associated with serious side-effects, such as thrombosis. This book describes the fundamentals of cardiovascular stents, technologies to functionalize their surfaces and the market status of these important implants. The chapters provide specific focus on the production and evolution of cardiovascular stents, providing essential knowledge for researchers on advances in the field and knowledge of how cardiovascular stents are currently being "functionalized" in order to improve their biocompatibility and minimize negative outcomes in vivo. Provides a specific focus on cardiovascular stents Includes a range of topics covering the fundamentals, surface modification and biofunctionalization Provides essential knowledge for researchers on advances in the field

Functionalized Cardiovascular Stents

Functionalized Cardiovascular Stents
  • Author : J. Gerard Wall,Halina Podbielska,Magdalena Wawrzyńska
  • Publisher :Unknown
  • Release Date :2018
  • Total pages :351
  • ISBN : OCLC:1066550942
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Summary :

Biomaterials and Devices for the Circulatory System

Biomaterials and Devices for the Circulatory System
  • Author : Terence Gourlay,Richard A Black
  • Publisher :Unknown
  • Release Date :2010-10-28
  • Total pages :400
  • ISBN : 9780857090553
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Summary : Cardiovascular disease is one of the leading causes of death in the world today. Thanks to major advances in circulatory biomaterials and medical devices over the past few decades, many complications of this prevalent disease can be managed with great success for prolonged periods. Biomaterials and devices for the circulatory system reviews the latest developments in this important field and how they can be used to improve the success and safety in this industry. Part one discusses physiological responses to biomaterials with chapters on tissue response, blood interface and biocompatibility. Part two then reviews clinical applications including developments in valve technology, percutaneous valve replacement, bypass technologies and cardiovascular stents. Part three covers future developments in the field with topics such as nanomedicine, cardiac restoration therapy, biosensor technology in the treatment of cardiovascular disease and vascular tissue engineering. With its distinguished editors and international team of contributors Biomaterials and devices for the circulatory system is a vital reference for those concerned with bioengineering, medical devices and clinicians within this critical field. Reviews the latest developments in this important field and how they can be used to improve success and safety in the industry Both current clinical advances as well as future innovation are assessed taking a progressive view of the role of biomaterials in medical applications An examination of the physiological responses to biomaterials features tissue responses to implanted materials and strategies to improve the biocompatibility of medical devices

Surgical Tools and Medical Devices

Surgical Tools and Medical Devices
  • Author : Waqar Ahmed,Mark J. Jackson
  • Publisher :Unknown
  • Release Date :2016-05-21
  • Total pages :691
  • ISBN : 9783319334899
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Summary : This new edition presents information and knowledge on the field of biomedical devices and surgical tools. The authors look at the interactions between nanotechnology, nanomaterials, design, modeling, and tools for surgical and dental applications, as well as how nanostructured surfaces can be created for the purposes of improving cell adhesion between medical devices and the human body. Each original chapter is revised in this second edition and describes developments in coatings for heart valves, stents, hip and knee joints, cardiovascular devices, orthodontic applications, and regenerative materials such as bone substitutes. There are also 8 new chapters that address: Microvascular anastomoses Inhaler devices used for pulmonary delivery of medical aerosols Surface modification of interference screws Biomechanics of the mandible (a detailed case study) Safety and medical devices The synthesis of nanostructured material Delivery of anticancer molecules using carbon nanotubes Nano and micro coatings for medical devices This book is appropriate for engineers, material scientists, chemists, physicists, biologists, medical and dental professionals with an interest in biomedical devices and tools, and researchers in the same fields.

Bioresorbable Scaffolds

Bioresorbable Scaffolds
  • Author : Yoshinobu Onuma,Patrick W.J.C. Serruys
  • Publisher :Unknown
  • Release Date :2017-10-02
  • Total pages :533
  • ISBN : 9781498779777
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Summary : This book focuses on the coronary bioresorbable scaffold, a new interventional treatment for coronary artery disease, differentiated from a permanent metallic stent. The book provides an overview of the technology including non-clinical studies and clinical evidences in order to help clinicians understand the appropriate application of the technology and the optimal techniques of implantation. It covers the basics of bioresorbable scaffolds; bench test results; preclinical studies; clinical evidences; and tips and tricks of implantation.

Biomanufacturing

Biomanufacturing
  • Author : Chander Prakash,Sunpreet Singh,Rupinder Singh,Seeram Ramakrishna,B. S. Pabla,Sanjeev Puri,M. S. Uddin
  • Publisher :Unknown
  • Release Date :2019-03-20
  • Total pages :271
  • ISBN : 9783030139513
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Summary : ​Current Trends in Biomanufacturing focuses on cutting-edge research regarding the design, fabrication, assembly, and measurement of bio-elements into structures, devices, and systems. The field of biomaterial and biomanufacturing is growing exponentially in order to meet the increasing demands of for artificial joints, organs and bone-fixation devices. Rapid advances in the biological sciences and engineering are leading to newer and viable resources, methods and techniques that may providing better quality of life and more affordable health care services. The book covers the broad aspects of biomanufacturing, including: synthesis of biomaterials; implant coating techniques; spark plasma sintering; microwave processing; and cladding, powder metallurgy and electrospinning. The contributors illustrate the recent trends of biomanufacturing, highlighting the important aspects of biomaterial synthesis, and their use as feedstock of fabrication technologies and their characterization, along with their clinical practices. Current Trends in Biomanufacturing updates researchers and scientists the novelties and techniques of the field, as it summarises numerous aspects of biomanufacturing, including synthesis of biomaterials, fabrication of biomedical structures, their in-vivo/ in-vitro, mechanical analysis and associated ISO standards.

Degradation of Implant Materials

Degradation of Implant Materials
  • Author : Noam Eliaz
  • Publisher :Unknown
  • Release Date :2012-08-21
  • Total pages :516
  • ISBN : 9781461439424
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Summary : This book reviews the current understanding of the mechanical, chemical and biological processes that are responsible for the degradation of a variety of implant materials. All 18 chapters will be written by internationally renowned experts to address both fundamental and practical aspects of research into the field. Different failure mechanisms such as corrosion, fatigue, and wear will be reviewed, together with experimental techniques for monitoring them, either in vitro or in vivo. Procedures for implant retrieval and analysis will be presented. A variety of biomaterials (stainless steels, titanium and its alloys, nitinol, magnesium alloys, polyethylene, biodegradable polymers, silicone gel, hydrogels, calcium phosphates) and medical devices (orthopedic and dental implants, stents, heart valves, breast implants) will be analyzed in detail. The book will serve as a broad reference source for graduate students and researchers studying biomedicine, corrosion, surface science, and electrochemistry.

Biomedical Engineering and its Applications in Healthcare

Biomedical Engineering and its Applications in Healthcare
  • Author : Sudip Paul
  • Publisher :Unknown
  • Release Date :2019-11-08
  • Total pages :738
  • ISBN : 9789811337055
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Summary : This book illustrates the significance of biomedical engineering in modern healthcare systems. Biomedical engineering plays an important role in a range of areas, from diagnosis and analysis to treatment and recovery and has entered the public consciousness through the proliferation of implantable medical devices, such as pacemakers and artificial hips, as well as the more futuristic technologies such as stem cell engineering and 3-D printing of biological organs. Starting with an introduction to biomedical engineering, the book then discusses various tools and techniques for medical diagnostics and treatment and recent advances. It also provides comprehensive and integrated information on rehabilitation engineering, including the design of artificial body parts, and the underlying principles, and standards. It also presents a conceptual framework to clarify the relationship between ethical policies in medical practice and philosophical moral reasoning. Lastly, the book highlights a number of challenges associated with modern healthcare technologies.

Industrial Applications for Intelligent Polymers and Coatings

Industrial Applications for Intelligent Polymers and Coatings
  • Author : Majid Hosseini,Abdel Salam Hamdy Makhlouf
  • Publisher :Unknown
  • Release Date :2016-05-14
  • Total pages :710
  • ISBN : 9783319268934
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Summary : This book is a comprehensive collaboration on intelligent polymers and coatings for industrial applications by worldwide researchers and specialists. The authors cover the basis and fundamental aspects of intelligent polymers and coatings, challenges, and potential mechanisms and properties. They include recent and emerging industrial applications in medical, smart textile design, oil and gas, electronic, aerospace, and automobile industries as well as other applications including microsystems, sensors, and actuators, among others. The authors discuss the potential for future research in these areas for improvement and growth of marketable applications of intelligent polymers and coatings.

Design and Applications of Nanoparticles in Biomedical Imaging

Design and Applications of Nanoparticles in Biomedical Imaging
  • Author : Jeff W.M. Bulte,Michel M.J. Modo
  • Publisher :Unknown
  • Release Date :2016-11-25
  • Total pages :469
  • ISBN : 9783319421698
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Summary : This book covers the most recent advances in using nanoparticles for biomedical imaging, including magnetic resonance imaging (MRI), magnetic particle imaging (MPI), nuclear medicine, ultrasound (US) imaging, computed tomography (CT), and optical imaging. Topics include nanoparticles for MRI and MPI, siRNA delivery, theranostic nanoparticles for PET imaging of drug delivery, US nanoparticles for imaging drug delivery, inorganic nanoparticles for targeted CT imaging, and quantum dots for optical imaging. This book serves as a valuable resource for the fundamental science of diagnostic nanoparticles and their interactions with biological targets, providing a practical handbook for improved detection of disease and its clinical implementation.

Biomaterials in Clinical Practice

Biomaterials in Clinical Practice
  • Author : Fatima Zivic,Saverio Affatato,Miroslav Trajanovic,Matthias Schnabelrauch,Nenad Grujovic,Kwang Leong Choy
  • Publisher :Unknown
  • Release Date :2017-10-20
  • Total pages :830
  • ISBN : 9783319680255
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Summary : This book covers the properties of biomaterials that have found wide clinical applications, while also reviewing the state-of-the-art in the development towards future medical applications, starting with a brief introduction to the history of biomaterials used in hip arthroplasty. The book then reviews general types of biomaterials – polymers, ceramics, and metals, as well as different material structures such as porous materials and coatings and their applications – before exploring various current research trends, such as biodegradable and porous metals, shape memory alloys, bioactive biomaterials and coatings, and nanometals used in the diagnosis and therapy of cancer. In turn, the book discusses a range of methods and approaches used in connection with biomaterial properties and characterization – chemical properties, biocompatibility, in vivo behaviour characterisation, as well as genotoxicity and mutagenicity – and reviews various diagnostic techniques: histopathological analysis, imagining techniques, and methods for physicochemical and spectroscopic characterization. Properties of stent deployment procedures in cardiovascular surgeries, from aspects of prediction, development and deployment of stent geometries are presented on the basis of novel modelling approaches. The last part of the book presents the clinical applications of biomaterials, together with case studies in dentistry, knee and hip prosthesis. Reflecting the efforts of a multidisciplinary team of authors, gathering chemical engineers, medical doctors, physicists and engineers, it presents a rich blend of perspectives on the application of biomaterials in clinical practice. The book will provide clinicians with an essential review of currently available solutions in specific medical areas, also incorporating non-medical solutions and standpoints, thus offering them a broader selection of materials and implantable solutions. This work is the result of joint efforts of various academic and research institutions participating in WIMB Tempus project, 543898-TEMPUS-1-2013-1-ES-TEMPUS-JPHES, "Development of Sustainable Interrelations between Education, Research and Innovation at WBC Universities in Nanotechnologies and Advanced Materials where Innovation Means Business", co-funded by the Tempus Programme of the European Union.

Biomechanics of Coronary Atherosclerotic Plaque

Biomechanics of Coronary Atherosclerotic Plaque
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2020-03-15
  • Total pages :686
  • ISBN : 9780128171967
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Summary : Biomechanics of Coronary Atherosclerotic Plaque: From Model to Patient, Fourth Edition summarizes all biomechanical aspects of each living organ in one comprehensive reference. The first two volumes introduce Continuum Fluid and Solid Biomechanics approaches, with each subsequent volume covering the important biomechanical and clinical aspects. The key thought leaders in the field of Biomechanics of Living Organs have gathered together their expertise in this series, making it an essential reference for anyone working in this research area. This book presents the first such resource to cover fluid and solid biomechanical studies conducted in this last decade to increase our understanding of plaque initiation, growth and rupture and improve the design of medical devices and clinical interventions, including surgical procedures. Presents the main computational fluid dynamic studies performed, describing blood flow in healthy and pathological artery branches, including in coronary bifurcations Highlights the correlation between plaque initiation regions and blood shear stress amplitude Discusses the main biomechanical and mechanobiological models to highlight the importance of quantifying the residual and peak cap stresses and the presence of μ-calcifications to evaluate the risk of plaque rupture Introduces the most recent intravascular imaging biomarker techniques (elastography, palpography and modulography)

Intracranial Atherosclerosis

Intracranial Atherosclerosis
  • Author : Jong S. Kim,Louis R. Caplan,K. S. Lawrence Wong
  • Publisher :Unknown
  • Release Date :2009-01-26
  • Total pages :272
  • ISBN : 9781444300680
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Summary : Intracranial atherosclerosis is the dominant cause of stroke inover 70% of the world’s population. Globalization is leadingto an increasingly heterogeneous society everywhere. Advances inimaging techinology allow this previously inaccessible pathology tobe clinically studied. Edited by internationally renowned clinicians, IntracranialAtherosclerosis is the first book to examine intracranialcauses of stroke. Clinical practice is allied with basic science toguide all those with an interest in stroke on the diagnosis andmanagement of intracranial atherosclerosis.

Multiparticulate Drug Delivery

Multiparticulate Drug Delivery
  • Author : Ali R. Rajabi-Siahboomi
  • Publisher :Unknown
  • Release Date :2017-05-26
  • Total pages :396
  • ISBN : 9781493970124
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Summary : Authored by leading experts from academia, users and manufacturers, this book provides an authoritative account of the science and technology involved in multiparticulate drug delivery systems which offer superior clinical and technical advantages over many other specialized approaches in drug delivery. The book will cover market trends, potential benefits and formulation challenges for various types of multiparticulate systems. Drug solubility, dose, chemistry and therapeutic indications as well as excipient suitability coupled with manufacturing methods will be fully covered. Key approaches for taste-masking, delayed release and extended release of multiparticulates systems are of significant interest, especially their in-vivo and in-vitro performance. In addition, the principles of scale-up, QbD, and regulatory aspects of common materials used in this technology will be explained, as well as recent advances in materials and equipment enabling robust, flexible and cost-effective manufacture. Case studies illustrating best practices will also make the book a valuable resource to pharmaceutical scientists in industry and academia.

Imaging Coronary Arteries

Imaging Coronary Arteries
  • Author : David A. Dowe,Massimo Fioranelli,Paolo Pavone
  • Publisher :Unknown
  • Release Date :2013-11-26
  • Total pages :261
  • ISBN : 9788847026827
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Summary : In non-fatal cases, cardiovascular diseases are associated with a decreased quality of life as well as a substantial economic burden to society. Most sudden cardiac events are related to the complications of a non-stenosing marginal plaque. For this reason, the ability to properly identify the atherosclerotic plaque with rapid, non-invasive techniques is of utmost clinical interest in diagnostic workup and therapeutic planning of symptomatic patient. Nowadays CT produces high-quality images of the coronary arteries, in addition to defining their location and the extent of the atherosclerotic involvement. This new edition is enriched with two important additions. Firstly, dedicated chapters on intravascular ultrasound (IVUS), catheter angiography, and nuclear imaging have been included, with some discussions on theoretical techniques such as optical coherence tomography (OCT) and magnetic resonance imaging (MRI). Secondly, a completely new section comprising more than 70 clinical cases remarkably expands the horizons reached by the previous edition. This volume provides general practitioners and cardiologists with a basic understanding of the imaging techniques. For radiologists with no direct experience in cardiac imaging, the book serves as an important source of information on coronary pathophysiology and anatomy.

Plasma Polymer Films

Plasma Polymer Films
  • Author : Hynek Biederman
  • Publisher :Unknown
  • Release Date :2004
  • Total pages :386
  • ISBN : 9781860944673
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Summary : Plasma Polymer Films examines the current status of the deposition and characterization of fluorocarbon-, hydrocarbon- and silicon-containing plasma polymer films and nanocomposites, with plasma polymer matrix. It introduces plasma polymerization process diagnostics such as optical emission spectroscopy (OES, AOES), and describes special deposition techniques such as atmospheric pressure glow discharge. Important issues for applications such as degradation and stability are treated in detail, and structural characterization, basic electrical and optical properties and biomedical applications are discussed.

Processes and Phenomena on the Boundary Between Biogenic and Abiogenic Nature

Processes and Phenomena on the Boundary Between Biogenic and Abiogenic Nature
  • Author : Olga V. Frank-Kamenetskaya,Dmitry Yu. Vlasov,Elena G. Panova,Sofia N. Lessovaia
  • Publisher :Unknown
  • Release Date :2019-08-29
  • Total pages :909
  • ISBN : 9783030216146
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Summary : The book represents a collection of papers presented at VI International Symposium "Biogenic - abiogenic interactions in natural and anthropogenic systems" that was held on 24-27 September 2018 in Saint Petersburg (Russia). Papers in this book cover a wide range of topics connecting with interactions between biogenic and abiogenic components in lithosphere, biosphere and technosphere. The main regarding topics are following: methods for studying the interactions between biogenic and abiogenic components; geochemistry of biogenic-abiogenic systems; biomineralization and nature-like materials and technologies; medical geology; biomineralogy and organic mineralogy; biomineral interactions in soil; biodeterioration of natural and artificial materials; biomineral interactions in extreme environment.

Vibrational Spectroscopy for Tissue Analysis

Vibrational Spectroscopy for Tissue Analysis
  • Author : Ihtesham ur Rehman,Zanyar Movasaghi,Shazza Rehman
  • Publisher :Unknown
  • Release Date :2012-09-27
  • Total pages :356
  • ISBN : 9781439836088
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Summary : A rapidly growing field, vibrational spectroscopy has found applications in industries including pharmaceutical manufacture, food and drug safety, and process monitoring on production lines. In particular, interest in clinical spectroscopy is rising rapidly as researchers recognize the potential of the vibrational spectroscopic techniques—Infrared (IR) and Raman Spectroscopy—as noninvasive tissue diagnosis tools. However, the details of the characteristic peak frequencies and their relationship to specific functional groups present in the biological tissues have not been fully understood. Vibrational Spectroscopy for Tissue Analysis introduces IR and Raman Spectroscopy to those scientists who are either using these spectroscopic techniques to address clinical problems or planning to use spectroscopy to analyze clinical tissues and understand their chemical composition. By compiling the interpretations and understandings of the spectral peaks of the biological molecules in one place, this book aids in the understanding of IR and Raman Spectroscopy, and what these techniques can offer both in early diagnosis of the disease and monitoring of the progression of the disease. Despite the tremendous advances in the field of spectroscopy, where new applications are emerging at the pace of development, there are still areas of research that are crying for further exploration. This book bridges the gap between the spectroscopic research and medical applications.

Polymer Nanocomposites in Biomedical Engineering

Polymer Nanocomposites in Biomedical Engineering
  • Author : Kishor Kumar Sadasivuni,Deepalekshmi Ponnamma,Mariappan Rajan,Basheer Ahmed,Al-Maadeed Mariam Ali S A
  • Publisher :Unknown
  • Release Date :2019-03-18
  • Total pages :409
  • ISBN : 9783030047412
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Summary : This book presents a thorough discussion of the physics, biology, chemistry and medicinal science behind a new and important area of materials science and engineering: polymer nanocomposites. The tremendous opportunities of polymer nanocomposites in the biomedical field arise from their multitude of applications and their ability to satisfy the vastly different functional requirements for each of these applications. In the biomedical field, a polymer nanocomposite system must meet certain design and functional criteria, including biocompatibility, biodegradability, mechanical properties, and, in some cases, aesthetic demands. The content of this book builds on what has been learnt in elementary courses about synthesising polymers, different nanoparticles, polymer composites, biomedical requirements, uses of polymer nanocomposites in medicine as well as medical devices and the major mechanisms involved during each application. The impact of hybrid nanofillers and synergistic composite mixtures which are used extensively or show promising outcomes in the biomedical field are also discussed. These novel materials vary from inorganic/ceramic-reinforced nanocomposites for mechanical property improvement to peptide-based nanomaterials, with the chemistry designed to render the entire material biocompatible.

Coronary Lesions

Coronary Lesions
  • Author : Patrick W. Serruys,Martin B. Leon,Antonio Colombo,Michael J B Kutryk
  • Publisher :Unknown
  • Release Date :2001-09-13
  • Total pages :376
  • ISBN : 1853179361
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Summary : The interventional cardiologist has to tackle a diverse and complex range of coronary lesions. For this reason, the experts who compiled this volume contribute the best practices for overcoming plaque and thrombus in the coronary arteries. From simple to complicated anatomy, the direct approach to achieving optimal results is clearly described and illustrated. Each chapter focuses on a specific problem, and top quality angiograms illustrate the various coronary lesions. The editors, all experts and pioneers in the field of interventional cardiology, from stenting to myocardial revascularization, have assembled a team of internationally renowned contributors to offer their practical advice on how to approach lesions in a straight-forward, pragmatic fashion. This guide is indispensable for cardiologists and students of the field, as well as for general practitioners.

Advances in Biomaterials for Biomedical Applications

Advances in Biomaterials for Biomedical Applications
  • Author : Anuj Tripathi,Jose Savio Melo
  • Publisher :Unknown
  • Release Date :2017-01-24
  • Total pages :545
  • ISBN : 9789811033285
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Summary : This book highlights recent advances in the field of biomaterials design and the state of the art in biomaterials applications for biomedicine. Addressing key aspects of biomaterials, the book explores technological advances at multi-scale levels (macro, micro, and nano), which are used in applications related to cell and tissue regeneration. The book also discusses the future scope of bio-integrated systems. The contents are supplemented by illustrated examples, and schematics of molecular and cellular interactions with biomaterials/scaffolds are included to promote a better understanding of the complex biological mechanisms involved in material-to-biomolecule interactions. The book also covers factors that govern cell growth, differentiation, and regeneration in connection with the treatment and recovery of native biological systems. Tissue engineering, drug screening and delivery, and electrolyte complexes for biomedical applications are also covered in detail. This book offers a comprehensive reference guide for multi-disciplinary communities working in the area of biomaterials, and will benefit researchers and graduate students alike.