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Fundamental Statistical Principles for the Neurobiologist

Fundamental Statistical Principles for the Neurobiologist
  • Author : Stephen W. Scheff
  • Publisher :Unknown
  • Release Date :2016-02-11
  • Total pages :234
  • ISBN : 9780128050514
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Summary : Fundamental Statistical Principles for Neurobiologists introduces readers to basic experimental design and statistical thinking in a comprehensive, relevant manner. This book is an introductory statistics book that covers fundamental principles written by a neuroscientist who understands the plight of the neuroscience graduate student and the senior investigator. It summarizes the fundamental concepts associated with statistical analysis that are useful for the neuroscientist, and provides understanding of a particular test in language that is more understandable to this specific audience, with the overall purpose of explaining which statistical technique should be used in which situation. Different types of data are discussed such as how to formulate a research hypothesis, the primary types of statistical errors and statistical power, followed by how to actually graph data and what kinds of mistakes to avoid. Chapters discuss variance, standard deviation, standard error, mean, confidence intervals, correlation, regression, parametric vs. nonparametric statistical tests, ANOVA, and post hoc analyses. Finally, there is a discussion on how to deal with data points that appear to be "outliers" and what to do when there is missing data, an issue that has not sufficiently been covered in literature. An introductory guide to statistics aimed specifically at the neuroscience audience Contains numerous examples with actual data that is used in the analysis Gives the investigators a starting pointing for evaluating data in easy-to-understand language Explains in detail many different statistical tests commonly used by neuroscientists

Signal Processing and Machine Learning for Biomedical Big Data

Signal Processing and Machine Learning for Biomedical Big Data
  • Author : Ervin Sejdic,Tiago H. Falk
  • Publisher :Unknown
  • Release Date :2018-07-04
  • Total pages :606
  • ISBN : 9781351061216
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Summary : This will be a comprehensive, multi-contributed reference work that will detail the latest research and developments in biomedical signal processing related to big data medical analysis. It will describe signal processing, machine learning, and parallel computing strategies to revolutionize the world of medical analytics and diagnosis as presented by world class researchers and experts in this important field. The chapters will desribe tools that can be used by biomedical and clinical practitioners as well as industry professionals. It will give signal processing researchers a glimpse into the issues faced with Big Medical Data.

MEDINFO 2019: Health and Wellbeing e-Networks for All

MEDINFO 2019: Health and Wellbeing e-Networks for All
  • Author : L. Ohno-Machado,B. Séroussi
  • Publisher :Unknown
  • Release Date :2019-11-12
  • Total pages :2076
  • ISBN : 9781643680033
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Summary : Combining and integrating cross-institutional data remains a challenge for both researchers and those involved in patient care. Patient-generated data can contribute precious information to healthcare professionals by enabling monitoring under normal life conditions and also helping patients play a more active role in their own care. This book presents the proceedings of MEDINFO 2019, the 17th World Congress on Medical and Health Informatics, held in Lyon, France, from 25 to 30 August 2019. The theme of this year’s conference was ‘Health and Wellbeing: E-Networks for All’, stressing the increasing importance of networks in healthcare on the one hand, and the patient-centered perspective on the other. Over 1100 manuscripts were submitted to the conference and, after a thorough review process by at least three reviewers and assessment by a scientific program committee member, 285 papers and 296 posters were accepted, together with 47 podium abstracts, 7 demonstrations, 45 panels, 21 workshops and 9 tutorials. All accepted paper and poster contributions are included in these proceedings. The papers are grouped under four thematic tracks: interpreting health and biomedical data, supporting care delivery, enabling precision medicine and public health, and the human element in medical informatics. The posters are divided into the same four groups. The book presents an overview of state-of-the-art informatics projects from multiple regions of the world; it will be of interest to anyone working in the field of medical informatics.

Principles of Neurobiology

Principles of Neurobiology
  • Author : Liqun Luo
  • Publisher :Unknown
  • Release Date :2020-09-05
  • Total pages :734
  • ISBN : 9781000096804
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Summary : Principles of Neurobiology, Second Edition presents the major concepts of neuroscience with an emphasis on how we know what we know. The text is organized around a series of key experiments to illustrate how scientific progress is made and helps upper-level undergraduate and graduate students discover the relevant primary literature. Written by a single author in a clear and consistent writing style, each topic builds in complexity from electrophysiology to molecular genetics to systems level in a highly integrative approach. Students can fully engage with the content via thematically linked chapters and will be able to read the book in its entirety in a semester-long course. Principles of Neurobiology is accompanied by a rich package of online student and instructor resources including animations, figures in PowerPoint, and a Question Bank for adopting instructors.

Medical Journal of Australia

Medical Journal of Australia
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :1972
  • Total pages :229
  • ISBN : UCLA:31158000576628
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Summary :

Statistical Signal Processing for Neuroscience and Neurotechnology

Statistical Signal Processing for Neuroscience and Neurotechnology
  • Author : Karim G. Oweiss
  • Publisher :Unknown
  • Release Date :2010-09-22
  • Total pages :433
  • ISBN : 0080962963
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Summary : This is a uniquely comprehensive reference that summarizes the state of the art of signal processing theory and techniques for solving emerging problems in neuroscience, and which clearly presents new theory, algorithms, software and hardware tools that are specifically tailored to the nature of the neurobiological environment. It gives a broad overview of the basic principles, theories and methods in statistical signal processing for basic and applied neuroscience problems. Written by experts in the field, the book is an ideal reference for researchers working in the field of neural engineering, neural interface, computational neuroscience, neuroinformatics, neuropsychology and neural physiology. By giving a broad overview of the basic principles, theories and methods, it is also an ideal introduction to statistical signal processing in neuroscience. A comprehensive overview of the specific problems in neuroscience that require application of existing and development of new theory, techniques, and technology by the signal processing community Contains state-of-the-art signal processing, information theory, and machine learning algorithms and techniques for neuroscience research Presents quantitative and information-driven science that has been, or can be, applied to basic and translational neuroscience problems

Advanced Data Analysis in Neuroscience

Advanced Data Analysis in Neuroscience
  • Author : Daniel Durstewitz
  • Publisher :Unknown
  • Release Date :2017-09-15
  • Total pages :292
  • ISBN : 9783319599762
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Summary : This book is intended for use in advanced graduate courses in statistics / machine learning, as well as for all experimental neuroscientists seeking to understand statistical methods at a deeper level, and theoretical neuroscientists with a limited background in statistics. It reviews almost all areas of applied statistics, from basic statistical estimation and test theory, linear and nonlinear approaches for regression and classification, to model selection and methods for dimensionality reduction, density estimation and unsupervised clustering. Its focus, however, is linear and nonlinear time series analysis from a dynamical systems perspective, based on which it aims to convey an understanding also of the dynamical mechanisms that could have generated observed time series. Further, it integrates computational modeling of behavioral and neural dynamics with statistical estimation and hypothesis testing. This way computational models in neuroscience are not only explanat ory frameworks, but become powerful, quantitative data-analytical tools in themselves that enable researchers to look beyond the data surface and unravel underlying mechanisms. Interactive examples of most methods are provided through a package of MatLab routines, encouraging a playful approach to the subject, and providing readers with a better feel for the practical aspects of the methods covered. "Computational neuroscience is essential for integrating and providing a basis for understanding the myriads of remarkable laboratory data on nervous system functions. Daniel Durstewitz has excellently covered the breadth of computational neuroscience from statistical interpretations of data to biophysically based modeling of the neurobiological sources of those data. His presentation is clear, pedagogically sound, and readily useable by experts and beginners alike. It is a pleasure to recommend this very well crafted discussion to experimental neuroscientists as well as mathematically well versed Physicists. The book acts as a window to the issues, to the questions, and to the tools for finding the answers to interesting inquiries about brains and how they function." Henry D. I. Abarbanel Physics and Scripps Institution of Oceanography, University of California, San Diego “This book delivers a clear and thorough introduction to sophisticated analysis approaches useful in computational neuroscience. The models described and the examples provided will help readers develop critical intuitions into what the methods reveal about data. The overall approach of the book reflects the extensive experience Prof. Durstewitz has developed as a leading practitioner of computational neuroscience. “ Bruno B. Averbeck

Head First Statistics

Head First Statistics
  • Author : Dawn Griffiths
  • Publisher :Unknown
  • Release Date :2008-08-26
  • Total pages :716
  • ISBN : 9780596800864
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Summary : A comprehensive introduction to statistics that teaches the fundamentals with real-life scenarios, and covers histograms, quartiles, probability, Bayes' theorem, predictions, approximations, random samples, and related topics.

Neurobiology of Attention

Neurobiology of Attention
  • Author : Laurent Itti,Geraint Rees,John K. Tsotsos
  • Publisher :Unknown
  • Release Date :2005-03-31
  • Total pages :744
  • ISBN : 0080454313
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Summary : A key property of neural processing in higher mammals is the ability to focus resources by selectively directing attention to relevant perceptions, thoughts or actions. Research into attention has grown rapidly over the past two decades, as new techniques have become available to study higher brain function in humans, non-human primates, and other mammals. Neurobiology of Attention is the first encyclopedic volume to summarize the latest developments in attention research. An authoritative collection of over 100 chapters organized into thematic sections provides both broad coverage and access to focused, up-to-date research findings. This book presents a state-of-the-art multidisciplinary perspective on psychological, physiological and computational approaches to understanding the neurobiology of attention. Ideal for students, as a reference handbook or for rapid browsing, the book has a wide appeal to anybody interested in attention research. * Contains numerous quick-reference articles covering the breadth of investigation into the subject of attention * Provides extensive introductory commentary to orient and guide the reader * Includes the most recent research results in this field of study

Cornell University Courses of Study

Cornell University Courses of Study
  • Author : Cornell University
  • Publisher :Unknown
  • Release Date :2007
  • Total pages :229
  • ISBN : CORNELL:31924097790251
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Summary :

Neurobiology of Motor Control

Neurobiology of Motor Control
  • Author : Scott L. Hooper,Ansgar Büschges
  • Publisher :Unknown
  • Release Date :2017-06-21
  • Total pages :512
  • ISBN : 9781118873625
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Summary : A multi-disciplinary look at the current state of knowledge regarding motor control and movement—from molecular biology to robotics The last two decades have seen a dramatic increase in the number of sophisticated tools and methodologies for exploring motor control and movement. Multi-unit recordings, molecular neurogenetics, computer simulation, and new scientific approaches for studying how muscles and body anatomy transform motor neuron activity into movement have helped revolutionize the field. Neurobiology of Motor Control brings together contributions from an interdisciplinary group of experts to provide a review of the current state of knowledge about the initiation and execution of movement, as well as the latest methods and tools for investigating them. The book ranges from the findings of basic scientists studying model organisms such as mollusks and Drosophila, to biomedical researchers investigating vertebrate motor production to neuroengineers working to develop robotic and smart prostheses technologies. Following foundational chapters on current molecular biological techniques, neuronal ensemble recording, and computer simulation, it explores a broad range of related topics, including the evolution of motor systems, directed targeted movements, plasticity and learning, and robotics. Explores motor control and movement in a wide variety of organisms, from simple invertebrates to human beings Offers concise summaries of motor control systems across a variety of animals and movement types Explores an array of tools and methodologies, including electrophysiological techniques, neurogenic and molecular techniques, large ensemble recordings, and computational methods Considers unresolved questions and how current scientific advances may be used to solve them going forward Written specifically to encourage interdisciplinary understanding and collaboration, and offering the most wide-ranging, timely, and comprehensive look at the science of motor control and movement currently available, Neurobiology of Motor Control is a must-read for all who study movement production and the neurobiological basis of movement—from molecular biologists to roboticists.

Neurobiology of Mental Illness

Neurobiology of Mental Illness
  • Author : Dennis S. Charney,Eric J. Nestler
  • Publisher :Unknown
  • Release Date :2011-05-20
  • Total pages :1504
  • ISBN : 0199857547
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Summary : This is a new edition of the first comprehensive text to show how the advances in molecular and cellular biology and in the basic neurosciences have brought the revolution in molecular medicine to the field of psychiatry. The book begins with a review of basic neuroscience and methods for studying neurobiology in human patients then proceeds to discussions of all major psychiatric syndromes with respect to knowledge of their etiology, pathophysiology, and treatment. Emphasis is placed on synthesizing information across numerous levels of analysis, including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, and behavior, and in translating information from the basic laboratory to the clinical laboratory and finally to clinical treatment. Editors Dennis Charney and Eric Nestle, along with their six section editors and over 150 contributors, have revised and updated all 80 chapters from the previous edition and have added new chapters on topics relating to, for example, genetics, experimental therapeutics, and late-life mood disorders. Both a textbook and a reference book, Neurobiology of Mental Illness is intended for psychiatrists, neuroscientists, and upper level students.

Analysis of Neural Data

Analysis of Neural Data
  • Author : Robert E. Kass,Uri T. Eden,Emery N. Brown
  • Publisher :Unknown
  • Release Date :2014-07-08
  • Total pages :648
  • ISBN : 9781461496021
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Summary : Continual improvements in data collection and processing have had a huge impact on brain research, producing data sets that are often large and complicated. By emphasizing a few fundamental principles, and a handful of ubiquitous techniques, Analysis of Neural Data provides a unified treatment of analytical methods that have become essential for contemporary researchers. Throughout the book ideas are illustrated with more than 100 examples drawn from the literature, ranging from electrophysiology, to neuroimaging, to behavior. By demonstrating the commonality among various statistical approaches the authors provide the crucial tools for gaining knowledge from diverse types of data. Aimed at experimentalists with only high-school level mathematics, as well as computationally-oriented neuroscientists who have limited familiarity with statistics, Analysis of Neural Data serves as both a self-contained introduction and a reference work.

Principles of Neural Science

Principles of Neural Science
  • Author : Eric R. Kandel,James H. Schwartz,Thomas M. Jessell
  • Publisher :Unknown
  • Release Date :1991
  • Total pages :1135
  • ISBN : 0838580688
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Summary :

Neurobiology of Language

Neurobiology of Language
  • Author : Gregory Hickok,Steven L. Small
  • Publisher :Unknown
  • Release Date :2015-08-15
  • Total pages :1188
  • ISBN : 9780124078628
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Summary : Neurobiology of Language explores the study of language, a field that has seen tremendous progress in the last two decades. Key to this progress is the accelerating trend toward integration of neurobiological approaches with the more established understanding of language within cognitive psychology, computer science, and linguistics. This volume serves as the definitive reference on the neurobiology of language, bringing these various advances together into a single volume of 100 concise entries. The organization includes sections on the field's major subfields, with each section covering both empirical data and theoretical perspectives. "Foundational" neurobiological coverage is also provided, including neuroanatomy, neurophysiology, genetics, linguistic, and psycholinguistic data, and models. Foundational reference for the current state of the field of the neurobiology of language Enables brain and language researchers and students to remain up-to-date in this fast-moving field that crosses many disciplinary and subdisciplinary boundaries Provides an accessible entry point for other scientists interested in the area, but not actively working in it – e.g., speech therapists, neurologists, and cognitive psychologists Chapters authored by world leaders in the field – the broadest, most expert coverage available

The Design of Experiments in Neuroscience

The Design of Experiments in Neuroscience
  • Author : Mary Harrington
  • Publisher :Unknown
  • Release Date :2010-09-13
  • Total pages :261
  • ISBN : 9781412974325
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Summary : “You are about to start on a great adventure. You are going to transition from reading about science to becoming a scientist.” -From the Preface Using engaging, disarming prose, author Mary Harrington shows neuroscience students how to go about selecting a topic, designing an experiment, analyzing the results, and publishing a paper. This text effectively illustrates basic research methods and design principles by uniquely using relevant examples from neuroscience such as the principles of design of fMRI studies, the use of transgenic mice, and conditional gene knockouts. The author also addresses basic professional ethics, fundamental statistics and data analysis tools, the range of possible experimental designs (from simple descriptive studies to multifactorial designs), and ways to control unwanted variables and avoid common pitfalls. This text is intended as either a core or supplemental text for both undergraduates and graduate students studying research methods in Neuroscience, Neuroanatomy, Neurophysiology, Neurochemistry, or Biological Psychology.

Courses and Degrees

Courses and Degrees
  • Author : Stanford University
  • Publisher :Unknown
  • Release Date :1988
  • Total pages :229
  • ISBN : STANFORD:36105032498144
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Summary :

Laboratory Techniques in Neuropsychology and Neurobiology

Laboratory Techniques in Neuropsychology and Neurobiology
  • Author : R. D. Myers
  • Publisher :Unknown
  • Release Date :1971
  • Total pages :356
  • ISBN : 0125123019
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Summary :

Proteomic Profiling and Analytical Chemistry

Proteomic Profiling and Analytical Chemistry
  • Author : Pawel Ciborowski,Jerzy Silberring
  • Publisher :Unknown
  • Release Date :2012-12-31
  • Total pages :264
  • ISBN : 9780444593917
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Summary : Proteomic Profiling and Analytical Chemistry helps scientists without a strong background in analytical chemistry to understand basic analytical principles and apply them to proteomics profiling. In most proteomic profiling experiments, liquid chromatography is used; this method is also used widely in analytical chemistry. This book bridges the gap between overly specialized courses and books in mass spectrometry, proteomics and analytical chemistry. It also helps researchers with an analytical chemistry background to break into the proteomics field. Proteomic Profiling and Analytical Chemistry focuses on practical applications for proteomic research helping readers to design better experiments and to more easily interpret, analyze and validate the resulting data. Experimental aspects such as sample preparation, protein extraction and precipitation, gel electrophoresis, microarrays, dynamics of fluorescent dyes, and more are all covered in detail. Covers the analytical consequences of protein and peptide modifications that may have a profound effect on how and what researchers actually measure Includes practical examples illustrating the importance of problems in quantitation and validation of biomarkers Helps in designing and executing proteomic experiments with sound analytics

Methods in Psychobiology: Laboratory techniques in neuropsychology and neurobiology

Methods in Psychobiology: Laboratory techniques in neuropsychology and neurobiology
  • Author : R. D. Myers
  • Publisher :Unknown
  • Release Date :1971
  • Total pages :356
  • ISBN : UOM:39015049441606
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Summary :

Principles of Addiction Medicine

Principles of Addiction Medicine
  • Author : Richard K. Ries,Shannon C. Miller,David A. Fiellin
  • Publisher :Unknown
  • Release Date :2009
  • Total pages :1570
  • ISBN : 0781774772
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Summary : This respected text from the American Society of Addiction Medicine is valuable for all physicians and mental-health personnel who specialize in addiction medicine and who treat patients with addiction disorders. The chapters blend scientific principles underlying addiction with the practical essentials of clinical addiction medicine. Many of the contributors are affiliated with leading government agencies that study addiction and its science, such as the National Institute on Alcohol Abuse and Alcoholism and the National Institute on Drug Abuse. The book will appeal to a wide and interdisciplinary range of professionals, especially those with interest or duties relating to addiction-related disorders, and in particular physicians seeking certification status via either the American Board of Addiction Medicine or the American Board of Psychiatry and Neurology. A companion Website will offer the fully searchable text.