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Fundamentals of Toxicologic Pathology

Fundamentals of Toxicologic Pathology
  • Author : Wanda M. Haschek,Colin G. Rousseaux,Matthew A. Wallig
  • Publisher :Unknown
  • Release Date :2009-11-23
  • Total pages :714
  • ISBN : 0080919324
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Summary : Toxicologic pathology integrates toxicology and the disciplines within it (such as biochemistry, pharmacodynamics and risk assessment) to pathology and its related disciplines (such as physiology, microbiology, immunology, and molecular biology). Fundamentals of Toxicologic Pathology Second Edition updates the information presented in the first edition, including five entirely new chapters addressing basic concepts in toxicologic pathology, along with color photomicrographs that show examples of specific toxicant-induced diseases in animals. The current edition also includes comparative information that will prove a valuable resource to practitioners, including diagnostic pathologists and toxicologists. 25% brand new information, fully revised throughout New chapters: Veterinary Diagnostic Toxicologic Pathology; Clinical Pathology; Nomenclature: Terminology for Morphologic Alterations; Techniques in Toxicologic Pathology New color photomicrographs detailing specific toxicant-induced diseases in animals Mechanistic information integrated from both toxicology and pathology discussing basic mechanisms of toxic injury and morphologic expression at the subcellular, cellular, and tissue levels

Haschek and Rousseaux's Handbook of Toxicologic Pathology

Haschek and Rousseaux's Handbook of Toxicologic Pathology
  • Author : Wanda M. Haschek,Colin G. Rousseaux,Matthew A. Wallig
  • Publisher :Unknown
  • Release Date :2013-05-01
  • Total pages :3054
  • ISBN : 9780124157651
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Summary : Haschek and Rousseaux's Handbook of Toxicologic Pathology is a key reference on the integration of structure and functional changes in tissues associated with the response to pharmaceuticals, chemicals and biologics. The 3e has been expanded by a full volume, and covers aspects of safety assessment not discussed in the 2e. Completely revised with many new chapters, it remains the most authoritative reference on toxicologic pathology for scientists and researchers studying and making decisions on drugs, biologics, medical devices and other chemicals, including agrochemicals and environmental contaminants. New topics include safety assessment, the drug life cycle, risk assessment, communication and management, carcinogenicity assessment, pharmacology and pharmacokinetics, biomarkers in toxicologic pathology, quality assurance, peer review, agrochemicals, nanotechnology, food and toxicologic pathology, the environment and toxicologic pathology and more. Provides new chapters and in-depth discussion of timely topics in the area of toxicologic pathology and broadens the scope of the audience to include toxicologists and pathologists working in a variety of settings Offers high-quality and trusted content in a multi-contributed work written by leading international authorities in all areas of toxicologic pathology Features hundreds of full color images in both the print and electronic versions of the book to highlight difficult concepts with clear illustrations

Fundamental Neuropathology for Pathologists and Toxicologists

Fundamental Neuropathology for Pathologists and Toxicologists
  • Author : Brad Bolon,Mark Butt
  • Publisher :Unknown
  • Release Date :2011-08-08
  • Total pages :648
  • ISBN : 9781118002230
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Summary : This book offers pathologists, toxicologists, other medical professionals, and students an introduction to the discipline and techniques of neuropathology – including chemical and environmental, biological, medical, and regulatory details important for performing an analysis of toxicant-induced neurodiseases. In addition to a section on fundamentals, the book provides detailed coverage of current practices (bioassays, molecular analysis, and nervous system pathology) and practical aspects (data interpretation, regulatory considerations, and tips for preparing reports).

Fundamentals of Toxicology

Fundamentals of Toxicology
  • Author : PK Gupta
  • Publisher :Unknown
  • Release Date :2016-08-26
  • Total pages :422
  • ISBN : 9780128054031
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Summary : Fundamentals of Toxicology: Essential Concepts and Applications provides a crisp, easy-to-understand overview of the most important concepts, applications, and ideas needed to learn the basics of toxicology. Written by a pre-eminent toxicologist with over five decades of teaching experience, this comprehensive resource offers the hands-on knowledge needed for a strong foundation in the wide field of toxicology. Fundamentals of Toxicology includes a clear structure divided into five units to assist learning and understanding. The first unit provides extensive coverage on the background of toxicology including commonly used definitions and historical perspective, while following units cover: basic concepts; regulatory requirements and good laboratory practices, including types of toxicology testing and evaluation; toxic agents and adverse effects on health; and analytical, forensic, and diagnostic toxicology. This is an essential book for advanced students in toxicology and across the biomedical sciences, life sciences, and environmental sciences who want to learn the concepts of toxicology, as well as early researchers needing to refresh outside of their specialty. Explains the essential concepts of toxicology in a clear fashion Provides in-depth coverage of testing protocols, common drugs, chemicals, and laboratory-based diagnostic and analytical toxicology Explores the history, foundations, and most recent concepts of toxicology Serves as an essential reference for advanced students in toxicology and across the biomedical, life, and environmental sciences who want to learn the concepts of toxicology

Boorman's Pathology of the Rat

Boorman's Pathology of the Rat
  • Author : Andrew W. Suttie,Joel R. Leininger,Alys E. Bradley
  • Publisher :Unknown
  • Release Date :2017-12-18
  • Total pages :748
  • ISBN : 9780123914897
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Summary : Boorman’s Pathology of the Rat: Reference and Atlas, Second Edition, continues its history as the most comprehensive pathology reference on rat strains for researchers across science and medicine using rat models in the laboratory. It offers readers an added emphasis on the Sprague-Dawley and Wistar rat strains that is consistent with current research across academia, government, and industry. In addition, the book provides standard diagnostic criteria, basic content on histology, histological changes that result from drug toxicity and neoplasm, pathology terminology, and four-color photographs from the NTP archive and database. With updated references and photographs, as well as coverage of all rat strains, this book is not only the standard in the field, but also an invaluable resource for toxicologists, biologists, and other scientists engaged in regulatory toxicology who must make the transition from pathology results to the promulgation of meaningful regulations. Contains full, four color photographs from the NTP archive and database and coverage of all rat strains Provides an organ-by-organ and system-by-system approach that presents standard diagnostic criteria and basic content on histology and histological changes Includes comprehensive and detailed background incidence data Presents detailed descriptive content regarding changes in rat models during research

Fundamentals of Plant Pathology

Fundamentals of Plant Pathology
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2013
  • Total pages :433
  • ISBN : 9781259029554
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Summary :

Toxicologic Pathology for Non-Pathologists

Toxicologic Pathology for Non-Pathologists
  • Author : Thomas J. Steinbach,Daniel J. Patrick,Mary Ellen Cosenza
  • Publisher :Unknown
  • Release Date :2019-10-31
  • Total pages :919
  • ISBN : 9781493997770
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Summary : This extensive volume began as a short course primarily geared toward toxicologists who want to expand their understanding of toxicologic pathology in order to be better study directors while also proving to be of great interest to other drug development scientists and regulatory reviewers. The overall goal is to help non-pathologists understand, contextualize, and communicate the pathology data and interpretations from the study pathologist in a practical and usable format. Within the book, readers will find an overview of general pathology concepts that include fundamental vocabulary and the basics of pathophysiological processes, along with numerous chapters devoted to pathology in specific organ systems as well as topics such as biomarkers, correlation of clinical pathology endpoints (chemistry and hematology) with microscopic changes, and well-known pathology findings for classes of toxic substances. Authoritative, practical, and comprehensive, Toxicologic Pathology for Non-Pathologists aims to help non-pathologists understand, converse in, and apply a basic understanding of pathology in their day-to-day careers.

Pesticide Toxicology and International Regulation

Pesticide Toxicology and International Regulation
  • Author : Timothy T. Marrs,Bryan Ballantyne
  • Publisher :Unknown
  • Release Date :2004-02-13
  • Total pages :592
  • ISBN : 0471496448
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Summary : This book brings together key features of the toxicology and occupational hazards of pesticides and the way their use is regulated in the main trading regions of the world. There are chapters on each of the main groups of insecticides, namely organochlorines, anticholinesterases and pyrethrins and pyrethroids. The book also covers fungicides and herbicides, as well as more specialised agents such as microbial pesticides. The risks and hazards to humans are considered, both occupational and through the consumption of contaminated foodstuffs. Additionally, clinical aspects of pesticide poisoning are discussed. The possibility of harm from pesticide exposure has led to the development of national and international regulations governing the application of pesticides. The book describes the regulatory systems in three major economic areas: the North American Free Trade Area (USA, Canada and Mexico), the European Union and Japan. This book should be of interest to all individuals working on the development and application of pesticides anywhere in the world. All those involved in the manufacture, regulation and toxicology of pesticides should also benefit from reading this book.

Pathology of the Developing Mouse

Pathology of the Developing Mouse
  • Author : Brad Bolon
  • Publisher :Unknown
  • Release Date :2015-04-24
  • Total pages :446
  • ISBN : 9781420070095
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Summary : Pathology of the Developing Mouse provides, in so far as feasible, one complete reference on the design, analysis, and interpretation of abnormal findings that may be detected in developing mice before and shortly after birth. In particular, this book is designed specifically to be not only a "how to do" manual for developmental pathology experimentation in mice but, more importantly, a "how to interpret" resource for pathologists and other biomedical scientists faced for the first or hundredth time with defining the significance of distorted features in some fantastic murine developmental monstrosity. The topics covered in this volume include a full range of subjects encountered when building and wielding a developmental pathology tool kit: baseline anatomic and physiologic traits of developing mice principles of good experimental design and statistical analysis for mouse developmental pathology studies procedures for anatomic pathology examinations, to evaluate structural changes at the macroscopic (gross), microscopic (cells and tissues), and ultrastructural (subcellular) levels, suing conventional autopsy-based or novel non-invasive imaging techniques; methods for clinical pathology testing, to assess the biochemical and cellular composition of tissues and fluids; options and protocols for in situ molecular pathology analysis, to undertake site-specific explorations of the various mechanisms responsible for producing adverse findings (i.e., "lesions") during development; and well-referenced and illustrated guides to the interpretation of anatomic pathology and clinical pathology changes in the animal (embryos, fetuses, neonates, and juveniles) and its support system (placenta).

Lu's Basic Toxicology

Lu's Basic Toxicology
  • Author : Frank C. Lu,Sam Kacew
  • Publisher :Unknown
  • Release Date :2002-05-23
  • Total pages :392
  • ISBN : 0415248558
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Summary : This classic textbook now enters its forth edition, offering a distillation of decades of research and teaching experience in toxicology. Known all over the world after its translation into six languages, Lu's Basic Toxicology: Fundamentals, Target Organs, and Risk Assessment is a benchmark text that brings clarity and insight into a rapidly evolving subject. Noted for its concise yet broad coverage of the subject, this new edition includes new chapters on over-the counter preparations, lactation and occupational toxicology. In addition, it covers: " The action of chemicals that cause cancer, mutations, congenital malformations and organ or system specific effects " Why chemical target specific organs and systems and how these effects are revealed by laboratory tests " The host and environmental factors that modify these effects " The effects of food additives, pesticides, metals, pollutants in air, water and soil, as well as toxicants encountered in workplaces " The procedures commonly used in assessing risk associated with these chemicals The breadth of this book makes it ideal for students requiring an introduction to toxicology, whether those specializing in toxicology or those from other biomedical disciplines who need a clear and concise overview of the field. The inclusion of separate subject and chemical indexes also makes it a useful shelf reference for more experienced researchers. In Lu's Basic Toxicology, Frank Lu and Sam Kacew have transcribed their vast experience to produce a book which will be an invaluable reference to student and practising toxicologists everywhere.

Atlas of Toxicological Pathology

Atlas of Toxicological Pathology
  • Author : Chirukandath Gopinath,Vasanthi Mowat
  • Publisher :Unknown
  • Release Date :2014-05-13
  • Total pages :285
  • ISBN : 9781627039987
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Summary : This atlas contains more than 700 illustrations that the authors have collected over the years as well as references and information pertaining to recently developed drug classes, including biologics. It is a useful bench reference for practicing pathologists and may also be used as a reference text by other experts from related fields. The atlas is organised into different chapters based on systemic pathology. Each chapter has illustrations with legends, and the atlas includes some rare examples of unique lesions found during toxicity studies over many years.

Small Animal Toxicology Essentials

Small Animal Toxicology Essentials
  • Author : Robert H. Poppenga,Sharon M. Gwaltney-Brant
  • Publisher :Unknown
  • Release Date :2011-11-16
  • Total pages :320
  • ISBN : 9781119946144
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Summary : Providing a ready reference for the initial triage, collection of diagnostic samples, and management of a poisoning case, Small Animal Toxicology Essentials focuses on the most common poisons encountered by companion animals. From prevention to evaluation, monitoring, and treatment, the book is a guide for veterinary technicians to differentiate between significant and insignificant exposures and effectively manage animal poisonings. Emphasizing clinical signs, differential diagnoses, and case management, the book begins with the principles of veterinary toxicology, such as terminology, history-taking, and decontamination. The second half of the book is devoted to specific toxicants, including plants, metals, drugs, and household poisons. A companion website at www.wiley.com/go/poppenga provides review questions in Word and color images available for download into PowerPoint. Small Animal Toxicology Essentials is a useful resource for veterinary technicians, especially those with a interest in emergency and critical care, and veterinary technician students, as well as practicing veterinarians looking for an introduction to toxicology.

Handbook of Forensic Toxicology for Medical Examiners

Handbook of Forensic Toxicology for Medical Examiners
  • Author : D. K. Molina, M.D.,Veronica Hargrove
  • Publisher :Unknown
  • Release Date :2018-06-13
  • Total pages :260
  • ISBN : 9781351260589
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Summary : Forensic professionals, particularly medical examiners—often working through heavy caseloads—require quick and easy access to reliable sources of information to help interpret toxicology results. While several in-depth resources are available, they are often large, cumbersome, and contain more information than is often needed. The Handbook of Forensic Toxicology for Medical Examiners is a concise handbook referencing the most common toxic substances and their reported non-toxic, toxic, and lethal concentrations, making it an ideal text for quick reference in the lab or autopsy room. Features of the Second Edition: Explains the principles of postmortem toxicology and the factors which must be considered Provides tables of toxicologic data for over 200 commonly encountered substances, including drugs of abuse, poisons, prescription drugs, and over-the-counter medications Includes discussion and description of the novel psychoactive drugs—including synthetic opioids, cannabinoids, stimulants and hallucinogens Supplemental appendices provide additional information regarding specimen types and selection, testing methodologies, normal laboratory values, and conversion charts The busy forensic professional needs a concise handbook that provides critical information quickly and accurately. This heavily referenced text offers an easy-to-use format allowing for rapid access for both routine daily use and preparation for courtroom testimony.

Fundamentals of Animal Science

Fundamentals of Animal Science
  • Author : Colin Scanes
  • Publisher :Unknown
  • Release Date :2010-01-01
  • Total pages :448
  • ISBN : 9781111781040
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Summary : FUNDAMENTALS OF ANIMAL SCIENCE is a research-based book that provides your students with balanced and comprehensive information on both companion animals, such as dogs and cats, and production animals such as horses, livestock, poultry and fish. This book provides an introductory overview on such key topics as animal production, rearing and products, and focuses on disciplines such as nutrition, reproduction, genetics and diseases. FUNDAMENTALS OF ANIMAL SCIENCE also includes sections on animal welfare, food safety, and how animals impact the environment. To foster classroom discussion and facilitate learning, this book presents related societal issues and discussion points for review and includes side bar definitions, multiple review questions, and illustrations that will help your students better understand the concepts of animal science. Important Notice: Media content referenced within the product description or the product text may not be available in the ebook version.

Fundamentals of Renal Pathology

Fundamentals of Renal Pathology
  • Author : Agnes B. Fogo,Arthur H. Cohen,Robert B. Colvin,J. Charles Jennette,Charles E. Alpers
  • Publisher :Unknown
  • Release Date :2013-10-24
  • Total pages :230
  • ISBN : 9783642390807
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Summary : Fundamentals of Renal Pathology is a compact and up-to-date resource on the basics of renal pathology that will be of particular value for residents and fellows in training in renal pathology, general pathology, and nephrology, but will also serve as a handy reference for the more experienced. This second, revised and updated edition of the book offers an integrated approach based on contributions from established experts in the field. Key diseases are discussed within the context of clinical presentations, with the emphasis on clinicopathological correlation and differential diagnosis. Topics discussed include glomerular diseases with nephrotic or nephritic syndrome presentations; systemic and vascular diseases affecting the kidney, including diseases affecting the renal transplant; tubulointerstitial diseases; and plasma cell dyscrasias and associated diseases. Well-chosen color illustrations and electron micrographs enhance and complement the text.

Comparative Anatomy and Histology

Comparative Anatomy and Histology
  • Author : Piper M. Treuting,Suzanne M. Dintzis,Kathleen S. Montine
  • Publisher :Unknown
  • Release Date :2017-08-29
  • Total pages :570
  • ISBN : 9780128029190
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Summary : The second edition of Comparative Anatomy and Histology is aimed at the new rodent investigator as well as medical and veterinary pathologists who need to expand their knowledge base into comparative anatomy and histology. It guides the reader through normal mouse and rat anatomy and histology using direct comparison to the human. The side by side comparison of mouse, rat, and human tissues highlight the unique biology of the rodents, which has great impact on the validation of rodent models of human disease. Offers the only comprehensive source for comparing mouse, rat, and human anatomy and histology through over 1500 full-color images, in one reference work Enables human and veterinary pathologists to examine tissue samples with greater accuracy and confidence Teaches biomedical researchers to examine the histologic changes in their model rodents Experts from both human and veterinary fields take readers through each organ system in a side-by-side comparative approach to anatomy and histology - human Netter anatomy images along with Netter-style rodent images

Haschek and Rousseaux's Handbook of Toxicologic Pathology

Haschek and Rousseaux's Handbook of Toxicologic Pathology
  • Author : Wanda M. Haschek,Colin G. Rousseaux,Matthew A. Wallig,Brad Bolon
  • Publisher :Unknown
  • Release Date :2021-09-15
  • Total pages :850
  • ISBN : 0128210443
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Summary : Haschek and Rousseaux's Handbook of Toxicologic Pathology: Volume 1: Principles and Practice of Toxicologic Pathology is a key reference on the integration of structure and functional changes in tissues associated with the response to pharmaceuticals, chemicals and biologics. Volume 1 of the Fourth Edition covers the practice of toxicologic pathology in three parts: Principles of Toxicologic Pathology, Methods in Toxicologic Pathology, and the Practice of Toxicologic Pathology. Completely revised with a number of new chapters, Volume 1 of the Handbook of Toxicologic Pathology is an essential part of the most authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists, and regulators studying and making decisions on drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants. Provides new chapters on digital pathology, juvenile pathology, in vitro/in vivo correlation, big data technologies and in-depth discussion of timely topics in the area of toxicologic pathology Offers high-quality and trusted content in a multi-contributed work written by leading international authorities in all areas of toxicologic pathology Features hundreds of full-color images in both the print and electronic versions of the book to highlight difficult concepts with clear illustrations

Fundamentals of Translational Neuroscience in Toxicologic Pathology

Fundamentals of Translational Neuroscience in Toxicologic Pathology
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2015
  • Total pages :229
  • ISBN : OCLC:1051898394
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Summary : A half-day Society of Toxicologic Pathology continuing education course on "Fundamentals of Translational Neuroscience in Toxicologic Pathology" presented some current major issues faced when extrapolating animal data regarding potential neurological consequences to assess potential human outcomes. Two talks reviewed functional–structural correlates in rodent and nonrodent mammalian brains needed to predict behavioral consequences of morphologic changes in discrete neural cell populations. The third lecture described practical steps for ensuring that specimens from rodent developmental neurotoxicity tests will be processed correctly to produce highly homologous sections. The fourth talk detailed demographic factors (e.g., species, strain, sex, and age); physiological traits (body composition, brain circulation, pharmacokinetic/pharmacodynamic patterns, etc.); and husbandry influences (e.g., group housing) known to alter the effects of neuroactive agents. The last presentation discussed the appearance, unknown functional effects, and potential relevance to humans of polyethylene glycol (PEG)–associated vacuoles within the choroid plexus epithelium of animals. Speakers provided real-world examples of challenges with data extrapolation among species or with study design considerations that may impact the interpretability of results. Translational neuroscience will be bolstered in the future as less invasive and/or more quantitative techniques are devised for linking overt functional deficits to subtle anatomic and chemical lesions.

Veterinary Hematology

Veterinary Hematology
  • Author : William J. Reagan,Armando R. Irizarry Rovira,Dennis B. DeNicola
  • Publisher :Unknown
  • Release Date :2019-05-21
  • Total pages :136
  • ISBN : 9781119064817
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Summary : Now in its third edition, Veterinary Hematology: Atlas of Common Domestic and Non-Domestic Species continues to offer veterinarians and veterinary technicians an essential guide to veterinary hematology. Comprehensive in scope, the atlas presents the fundamentals of both normal and abnormal blood cell morphologies, with coverage of a wide range of species, including dogs, cats, horses, ruminants, llamas, rats, mice, nonhuman primates, ferrets, rabbits, guinea pigs, birds, amphibians, and reptiles. Designed as a useful and accessible guide, the updated third edition presents more than 300 color images and includes a new chapter that describes the best techniques for using hematology instruments. The authors—noted experts on the topic—clearly show how to identify and interpret the hematological changes that may occur in a variety of species. In addition, a companion website offers a wealth of additional hematological images. This vital atlas: Provides an updated edition of the popular veterinary hematology atlas for veterinarians, veterinary students, and veterinary technicians Contains a new instructive chapter on hematology instrumentation Presents hundreds of high-quality color photographs that help in identification Covers a range of species from dogs and cats to birds and reptiles Features a companion website that provides a wealth of hematological images Written for both novice and experienced veterinarians, Veterinary Hematology provides a complete resource to blood morphologic abnormalities in domestic and non-domestic species.

Sustaining Life

Sustaining Life
  • Author : Eric Chivian,Aaron Bernstein
  • Publisher :Unknown
  • Release Date :2008-06-02
  • Total pages :568
  • ISBN : 9780199721207
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Summary : The Earth's biodiversity-the rich variety of life on our planet-is disappearing at an alarming rate. And while many books have focused on the expected ecological consequences, or on the aesthetic, ethical, sociological, or economic dimensions of this loss, Sustaining Life is the first book to examine the full range of potential threats that diminishing biodiversity poses to human health. Edited and written by Harvard Medical School physicians Eric Chivian and Aaron Bernstein, along with more than 100 leading scientists who contributed to writing and reviewing the book, Sustaining Life presents a comprehensive--and sobering--view of how human medicines, biomedical research, the emergence and spread of infectious diseases, and the production of food, both on land and in the oceans, depend on biodiversity. The book's ten chapters cover everything from what biodiversity is and how human activity threatens it to how we as individuals can help conserve the world's richly varied biota. Seven groups of organisms, some of the most endangered on Earth, provide detailed case studies to illustrate the contributions they have already made to human medicine, and those they are expected to make if we do not drive them to extinction. Drawing on the latest research, but written in language a general reader can easily follow, Sustaining Life argues that we can no longer see ourselves as separate from the natural world, nor assume that we will not be harmed by its alteration. Our health, as the authors so vividly show, depends on the health of other species and on the vitality of natural ecosystems. With a foreword by E.O. Wilson and a prologue by Kofi Annan, and more than 200 poignant color illustrations, Sustaining Life contributes essential perspective to the debate over how humans affect biodiversity and a compelling demonstration of the human health costs. It is the winner of the Gerald L. Young Book Award in Human Ecology Best Sci-Tech Books of 2008 for Biology by Gregg Sapp of Library Journal

Veterinary Assisting Fundamentals & Applications

Veterinary Assisting Fundamentals & Applications
  • Author : Beth Vanhorn,Robert Clark
  • Publisher :Unknown
  • Release Date :2010-06-22
  • Total pages :960
  • ISBN : 9781133417040
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Summary : Veterinary Assisting Fundamentals and Applications provides a well-rounded, complete approach to learning the skills required in the field of veterinary assisting. Beginning with basic skills such as veterinary medical terminology and office procedures, the book progresses to more advanced skills such as nursing care and radiology. There is a section on animal production and management covering companion animals, large animals, and exotic animals. Clinical scenarios are provided in each chapter to help demonstrate application of the skills to real world practice. Robust instructor support materials are also provided including an instructor’s guide, presentations on PowerPoint, and a testbank. Important Notice: Media content referenced within the product description or the product text may not be available in the ebook version.