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Gut Microbiota in Neurologic and Visceral Diseases

Gut Microbiota in Neurologic and Visceral Diseases
  • Author : Tahira Farooqui,Akhlaq A. Farooqui
  • Publisher :Unknown
  • Release Date :2021-03-15
  • Total pages :396
  • ISBN : 0128210397
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Summary : Gut Microbiota in Neurologic and Visceral Diseases presents readers with comprehensive information on the involvement of microbiota in the pathogenesis of neurological disorders. Chapters cover the effect of microbiota on the development of visceral (obesity, type 2 diabetes, heart disease) and neurological disorders (Alzheimer's disease, Parkinson's, depression, anxiety, and autism). Sections focus on the molecular mechanisms and signal transduction processes associated with the links among microbiota-related visceral and neurological disorders. It is hoped that this discussion will not only integrate and consolidate knowledge in this field but will also jumpstart more studies on the involvement of microbiota in the pathogenesis of neurological disorders. Reviews the relationship between gut microbiome, diseases and disorders Discusses the relationship between diet, microbiota and inflammation Includes neurodegenerative, neuropsychiatric and cardiovascular disorders Covers diabetes, obesity and metabolic disorders Identifies molecular mechanisms and signal transduction processes Encompasses dietary fiber, fat, prebiotics and probiotics

Insulin Resistance As a Risk Factor in Visceral and Neurological Disorders

Insulin Resistance As a Risk Factor in Visceral and Neurological Disorders
  • Author : Akhlaq A. Farooqui
  • Publisher :Unknown
  • Release Date :2020-03
  • Total pages :300
  • ISBN : 9780128196038
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Summary : Insulin Resistance as a Risk Factor in Visceral and Neurological Disorders provides an overview on the risk factors for insulin resistance in visceral and neurological disorders. The book focuses on molecular mechanisms and signal transduction processes associated with the links. The comprehensive information in this monograph will not only help in the early detection of insulin resistance related visceral and neurological disorders, but also promote the discovery of new drugs which may block or delay onset in elderly patients. Understanding these processes is important not only for patients, caregivers and health professionals, but also for health policymakers who must plan for national resources.

Microbial Endocrinology

Microbial Endocrinology
  • Author : Mark Lyte,Primrose P.E. Freestone
  • Publisher :Unknown
  • Release Date :2010-04-06
  • Total pages :316
  • ISBN : 9781441955760
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Summary : Microbial endocrinology represents a newly emerging interdisciplinary field that is formed by the intersection of the fields of neurobiology and microbiology. This book will introduce a new perspective to the current understanding not only of the factors that mediate the ability of microbes to cause disease, but also to the mechanisms that maintain normal homeostasis. The discovery that microbes can directly respond to neuroendocrine hormones, as evidenced by increased growth and production of virulence-associated factors, provides for a new framework with which to investigate how microorganisms interface not only with vertebrates, but also with invertebrates and even plants. The reader will learn that the neuroendocrine hormones that one most commonly associates with mammals are actually found throughout the plant, insect and microbial communities to an extent that will undoubtedly surprise many, and most importantly, how interactions between microbes and neuroendocrine hormones can influence the pathophysiology of infectious disease.

Microbial Endocrinology: The Microbiota-Gut-Brain Axis in Health and Disease

Microbial Endocrinology: The Microbiota-Gut-Brain Axis in Health and Disease
  • Author : Mark Lyte,John F. Cryan
  • Publisher :Unknown
  • Release Date :2014-07-05
  • Total pages :436
  • ISBN : 9781493908974
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Summary : The field of microbial endocrinology is expressly devoted to understanding the mechanisms by which the microbiota (bacteria within the microbiome) interact with the host (“us”). This interaction is a two-way street and the driving force that governs these interactions are the neuroendocrine products of both the host and the microbiota. Chapters include neuroendocrine hormone-induced changes in gene expression and microbial endocrinology and probiotics. This is the first in a series of books dedicated to understanding how bi-directional communication between host and bacteria represents the cutting edge of translational medical research, and hopefully identifies new ways to understand the mechanisms that determine health and disease.​

Gut Microbiota

Gut Microbiota
  • Author : Alper Evrensel,Barış Önen Ünsalver
  • Publisher :Unknown
  • Release Date :2018-12-12
  • Total pages :114
  • ISBN : 9781789848144
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Summary : The gut-brain axis has gained considerable attention from different branches of the scientific community in recent years. In this book, scientists from different disciplines present current scientific knowledge on the topic. The interaction between the prokaryote and eukaryote cells stimulates the evolutionary processes, and results in various systemic illnesses such as neuropsychiatric disorders and may help the continuity of health. Nature has provided us with healthy food that builds our pharmacy. This natural pharmacy store may help the body's healing processes through its effects on gut microbiota and the immune system. This book aims to provide the reader with detailed analyses of the current scientific knowledge on the gut-brain axis and its relation with health and disease. We hope that the reader benefits from the presented material.

The Microbiota in Gastrointestinal Pathophysiology

The Microbiota in Gastrointestinal Pathophysiology
  • Author : Martin H. Floch,Yehuda Ringel,W. Allen Walker
  • Publisher :Unknown
  • Release Date :2016-11-16
  • Total pages :442
  • ISBN : 9780128040621
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Summary : The Microbiota in Gastrointestinal Pathophysiology: Implications for Human Health, Prebiotics, Probiotics and Dysbiosis is a one-stop reference on the state-of-the-art research on gut microbial ecology in relation to human disease. This important resource starts with an overview of the normal microbiota of the gastrointestinal tract, including the esophagus, stomach, Ileum, and colon. The book then identifies what a healthy vs. unhealthy microbial community looks like, including methods of identification. Also included is insight into which features and contributions the microbiota make that are essential and useful to host physiology, as is information on how to promote appropriate mutualisms and prevent undesirable dysbioses. Through the power of synthesizing what is known by experienced researchers in the field, current gaps are closed, raising understanding of the role of the microbiome and allowing for further research. Explains how to modify the gut microbiota and how the current strategies used to do this produce their effects Explores the gut microbiota as a therapeutic target Provides the synthesis of existing data from both mainstream and non-mainstream sources through experienced researchers in the field Serves as a ‘one-stop’ shop for a topic that’s currently spread across a number of various journals

Molecular Aspects of Neurodegeneration, Neuroprotection, and Regeneration in Neurological Disorders

Molecular Aspects of Neurodegeneration, Neuroprotection, and Regeneration in Neurological Disorders
  • Author : Akhlaq A. Farooqui
  • Publisher :Unknown
  • Release Date :2020-09-07
  • Total pages :400
  • ISBN : 9780128217016
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Summary : Molecular Aspects of Neurodegeneration, Neuroprotection, and Regeneration in Neurological Disorders presents readers with comprehensive and cutting-edge information on the neurochemical mechanisms of various types of neurological disorders. The book covers information on signal transduction processes associated with neurochemistry of neurological disorders, including neurodegenerative, neurotraumatic, and neuropsychiatric disorders. The book also discusses risk factors, symptoms, pathogenesis, biomarkers, and the potential treatments of neurological disorders. The comprehensive information in this monograph may not only help in early detection of various neurological disorders, but will also promote the discovery of new drugs. Provides a comprehensive overview of the molecular aspects of neurodegeneration, neuroprotection, and neuro-regeneration, along with therapeutic strategies for various types of neurological disorders Provides cutting-edge research information on the signal transduction processes associated with the neurochemistry of neurological disorders Discusses risk factors, symptoms, pathogenesis, biomarkers, and the potential for treatments of neurological disorders

A Comprehensive Overview of Irritable Bowel Syndrome

A Comprehensive Overview of Irritable Bowel Syndrome
  • Author : Jakub Fichna
  • Publisher :Unknown
  • Release Date :2020-07-15
  • Total pages :298
  • ISBN : 9780128213254
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Summary : A Comprehensive Overview of Irritable Bowel Syndrome: Clinical and Basic Science Aspects presents up-to-date knowledge in the field and provides a comprehensive summary of this area of study, including an overview on IBS, starting from its pathogenesis, including genetic, microbial and physiological background, through symptom recognition, diagnosis and IBS treatment, both non-pharmacological and pharmacological. Compiles the most recent and comprehensive findings in pharmacological targets Highlights the role of extrinsic and intrinsic factors involved in disease development Written by leading researchers in the field of Irritable Bowel Syndrome to address research challenges in the field Includes bonus information on symptom recognition and diagnosis

Metabolic Syndrome and Neurological Disorders

Metabolic Syndrome and Neurological Disorders
  • Author : Akhlaq A. Farooqui,Tahira Farooqui
  • Publisher :Unknown
  • Release Date :2013-09-26
  • Total pages :576
  • ISBN : 9781118395288
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Summary : Metabolic Syndrome and Neurological Disorders brings together information on the cluster of common pathologies which cause metabolic syndrome - abdominal obesity linked to an excess of visceral fat, insulin resistance, dyslipidemia and hypertension - to provide a comprehensive and cutting edge exploration of the link between metabolic syndrome and neurological disorders. Metabolic syndrome is recognized to play a role in neurological disorders such as stroke, Alzheimer's disease, and depression. For the first time in book form, Metabolic Syndrome and Neurological Disorders covers the molecular mechanisms thought to underlie this mirror relationship, as well as how lifestyle and other factors such as oxidative stress and inflammation may play a role in the disease. Grounded in a series of epidemiological studies of metabolic-cognitive syndrome, this book will be a valuable reference for researchers, dietitians, nutritionists, and physicians.

Molecular Aspects of Neurodegeneration and Neuroprotection

Molecular Aspects of Neurodegeneration and Neuroprotection
  • Author : Akhlaq A. Farooqui,Tahira Farooqui
  • Publisher :Unknown
  • Release Date :2011-01-26
  • Total pages :146
  • ISBN : 9781608050925
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Summary : "Neurodegenerative diseases are a complex heterogeneous group of diseases associated with site-specific premature and slow death of certain neuronal populations in brain and spinal cord tissues. For example, in Alzheimer disease, neuronal degeneration occu"

Enteric Glia

Enteric Glia
  • Author : Brian D. Gulbransen
  • Publisher :Unknown
  • Release Date :2014-07-01
  • Total pages :70
  • ISBN : 9781615046614
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Summary : The enteric nervous system (ENS) is a complex neural network embedded in the gut wall that orchestrates the reflex behaviors of the intestine. The ENS is often referred to as the “little brain” in the gut because the ENS is more similar in size, complexity and autonomy to the central nervous system (CNS) than other components of the autonomic nervous system. Like the brain, the ENS is composed of neurons that are surrounded by glial cells. Enteric glia are a unique type of peripheral glia that are similar to astrocytes of the CNS. Yet enteric glial cells also differ from astrocytes in many important ways. The roles of enteric glial cell populations in the gut are beginning to come to light and recent evidence implicates enteric glia in almost every aspect of gastrointestinal physiology and pathophysiology. However, elucidating the exact mechanisms by which enteric glia influence gastrointestinal physiology and identifying how those roles are altered during gastrointestinal pathophysiology remain areas of intense research. The purpose of this e-book is to provide an introduction to enteric glial cells and to act as a resource for ongoing studies on this fascinating population of glia. Table of Contents: Introduction / A Historical Perspective on Enteric Glia / Enteric Glia: The Astroglia of the Gut / Molecular Composition of Enteric Glia / Development of Enteric Glia / Functional Roles of Enteric Glia / Enteric Glia and Disease Processes in the Gut / Concluding Remarks / References / Author Biography

New Insights into Inflammatory Bowel Disease

New Insights into Inflammatory Bowel Disease
  • Author : Samuel Huber
  • Publisher :Unknown
  • Release Date :2016-10-26
  • Total pages :264
  • ISBN : 9789535127543
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Summary : The incidence of chronic inflammatory and autoimmune diseases is steadily increasing. Inflammatory bowel disease (IBD) is one example of a chronic inflammatory disease, which primarily affects the intestine but may also affect extraintestinal organs. The exact pathogenesis of IBD is currently unknown. However, it is clear that the pathogenesis is complex, involving barrier defects, changes in the intestinal microbiome, and chronic immune activation. This book aims to summarize basic aspects of these complex interactions between barrier function, microbiome, and the immune system. Of note, there is currently no cure for IBD. However, several therapies have evolved in the last years, which are overall able to-at least temporarily-suppress IBD. These therapies and the underlying mechanism are discussed.

Diet and Exercise in Cognitive Function and Neurological Diseases

Diet and Exercise in Cognitive Function and Neurological Diseases
  • Author : Akhlaq A. Farooqui,Tahira Farooqui
  • Publisher :Unknown
  • Release Date :2015-03-23
  • Total pages :408
  • ISBN : 9781118840559
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Summary : Diet and Exercise in Cognitive Function and Neurological Diseases looks at the role and impact that nutrition and activity have on cognitive function and neurological health. The book is divided into the two sections. The first focuses on diet and its impact on neurobiological processes. Chapters focus on the impacts of specific diets, such as the Mediterranean diet, ketogenic and vegan diets, as well as the role specific nutrients, fats, fatty acids, and caloric intake have on neurological health and cognitive function. The second part of the book focuses on exercise, and its role in maintaining cognitive function, reducing neuroinflammatory responses, regulating adult neurogenesis, and healthy brain aging. Other chapters in this section look at the impacts of disease in the management of specific neurological disorders such multiple sclerosis and Parkinson’s disease. Collectively, the chapters in Diet and Exercise in Cognitive Function and Neurological Diseases come together to form a timely reference on the neurobiological interplay between diet and exercise on long-term brain health and cognitive function.

Brain-Gut Interactions

Brain-Gut Interactions
  • Author : Yvette Tache,David L. Wingate
  • Publisher :Unknown
  • Release Date :1991-02-22
  • Total pages :392
  • ISBN : 0849353688
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Summary : Brain-Gut Interactions serves as a reference source and stimulus for expanded research efforts aimed at unravelling the pathophysiology of brain-gut interactions. Within the general framework of brain-gut interactions, it covers the various areas in which this growing interdisciplinary field has evolved. Topics discussed in this volume include the topography and morphology of afferent and efferent connections between the gut and the medulla and hypothalamic nuclei, the role of afferent and efferent pathways in the regulation of gastrointestinal function, the brain's regulation of gastrointestinal secretory and motor function, and the function of peripheral and central cholecystokinin in the mechanisms of satiety. The final section of this book focuses on topics such as stress, emesis, visceral pain, and brain-related disorders of the intestine based on experimental and clinical data. Students and investigators working with brain-gut interactions, gastroenterologists, psychologists, and psychiatrists will find this book to be an essential reference resource.

The Gut Microbiome

The Gut Microbiome
  • Author : Gyula Mozsik
  • Publisher :Unknown
  • Release Date :2016-11-02
  • Total pages :112
  • ISBN : 9789535127505
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Summary : In the last decades, the importance of gut microbiome has been linked to medical research on different diseases. Developments of other medical disciplines (human clinical pharmacology, clinical nutrition and dietetics, everyday medical treatments of antibiotics, changes in nutritional inhabits in different countries) also called attention to study the changes in the gut microbiome. This book contains five excellent review chapters in the field of gut microbiome, written by researchers from the USA, Canada, China, and India. These chapters present a critical review about some clinically important changes in the gut microbiome in the development of some human diseases and therapeutic possibilities (liver disease, cardiovascular diseases, brain diseases, gastrointestinal diseases). The book brings to attention the essential role of gut microbiome in keeping our life healthy. This book is addressed to experts of microbiology, podiatrists, gastroenterologists, internists, nutritional experts, cardiologists, basic and clinical researchers, as well as experts in the field of food industry.

Gerontology

Gerontology
  • Author : Grazia D’Onofrio,Daniele Sancarlo,Antonio Greco
  • Publisher :Unknown
  • Release Date :2018-07-04
  • Total pages :276
  • ISBN : 9781789232523
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Summary : Aging well and actively is the real objective of human being. This book is an up-to-date and realistic view on physiopathological mechanisms of aging and age-related diseases. The book includes topical contributions from multiple disciplines to support the fundamental goals of extending active life and enhancing its quality.

The Mind-Gut Connection

The Mind-Gut Connection
  • Author : Emeran Mayer
  • Publisher :Unknown
  • Release Date :2018-06-05
  • Total pages :336
  • ISBN : 9780062846822
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Summary : Chances are, at some point in your life you’ve noticed the connection between your brain and your gut. If you’ve ever felt queasy as you walked into an uncomfortable situation or based a life decision based on a “gut feeling,” then you know that sometimes our bodies react faster than our minds. Most of us have also experienced the same phenomenon in reverse, where our mental state has affected our digestive system—like the butterflies in our stomach before an important meeting or a first date. But while the dialogue between the mind and the gut has been recognized for centuries, scientists today are just starting to understand how powerful that connection is. In The Mind-Gut Connection, Dr. Emeran Mayer, executive director of the UCLA Oppenheimer Center for the Neurobiology of Stress, offers a cutting-edge view into this developing science, showing us the full impact of how the brain, gut, and microbiome—the community of microorganisms that live inside the digestive tract—communicate. As Dr. Mayer explains, when this communication channel is out of whack, major health problems can crop up, including food sensitivities and allergies, digestive disorders, obesity, depression, anxiety, and fatigue. The Mind-Gut Connection teaches us how, with a few simple changes to our diet and lifestyle, we can enjoy a happier mindset, enhanced immunity, a decreased risk of developing neurological diseases such as Parkinson’s and Alzheimer’s, and even lose weight. With a simple, practical regimen drawn from the latest research, Dr. Mayer shows us that paying attention to the mind-gut balance is the key to unlocking vibrant health.

Chemotherapy-Induced Neuropathic Pain

Chemotherapy-Induced Neuropathic Pain
  • Author : Robert B. Raffa,Richard Langford,Joseph V. Pergolizzi Jr.,Frank Porreca,Ronald J. Tallarida
  • Publisher :Unknown
  • Release Date :2012-07-24
  • Total pages :233
  • ISBN : 9781439862193
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Summary : There have been tremendous recent advances in the pharmacotherapy, dose regimens, and combinations used to treat cancer and for the treatment or prevention of the spread of disease. As a direct result of these advances, there are an increasing number of cancer survivors, although research dealing with chemotherapy-induced pain is still in its early

Neurological Disorders

Neurological Disorders
  • Author : World Health Organization
  • Publisher :Unknown
  • Release Date :2006
  • Total pages :218
  • ISBN : 9789241563369
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Summary : Although there are several gaps in understanding the many issues related to neurological disorders, we know enough to be able to shape effective policy responses to some of the most common. This book describes and discusses the increasing public health impact of common neurological disorders such as dementia, epilepsy, headache disorders, multiple sclerosis, neuroinfections, neurological disorders associated with malnutrition, pain associated with neurological disorders, Parkinson's disease, stroke and traumatic brain injuries. It provides information and advice on public health interventions that may reduce their occurrence and consequences, and offers health professionals and planners the opportunity to assess the burden caused by these disorders. The clear message that emerges is that unless immediate action is taken globally, the neurological burden is likely to become an increasingly serious and unmanageable.

Melanin

Melanin
  • Author : Miroslav Blumenberg
  • Publisher :Unknown
  • Release Date :2017-03-01
  • Total pages :114
  • ISBN : 9789535129790
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Summary : The word melanin refers to dark natural pigments produced by the oxidative degradation of tyrosine, catalyzed by tyrosinase, and polymerized into insoluble granular substance. The main function of melanin is to protect from harmful agents, primarily UV radiation, but also from oxidation, heavy metals, etc. In this volume, chapters deal with production of melanin in human oral mucosa (Liviu et al.), the regulation of melanin action (Cecile et al.), production and potential technological application of fungal melanins (Pombiero-Sponchiado et al.) and an innovative method for measuring melanin in various samples (Zdybel et al.). In conclusion, this volume presents various biological and industrial aspects of melanin production, uses and analysis.

Clinical and Basic Neurogastroenterology and Motility

Clinical and Basic Neurogastroenterology and Motility
  • Author : Satish S.C. Rao,Yeong Yeh Lee,Uday C. Ghoshal
  • Publisher :Unknown
  • Release Date :2019-12-01
  • Total pages :660
  • ISBN : 9780128130384
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Summary : Clinical and Basic Neurogastroenterology and Motility is a state-of-the-art, lucidly written, generously illustrated, landmark publication that comprehensively addresses the underlying mechanisms and management of common adult and pediatric motility disorders. These problems affect 50% of the population and include conditions such as dysphagia, achalasia, gastroesophageal reflux disease, gastroparesis, irritable bowel syndrome (IBS), gas and bloating, SIBO, constipation and fecal incontinence. The book brings together international experts and clinician scientists, epitomizing their years of wisdom into a concise yet practical text that is delivered in two distinct sections, basic and clinical. It fulfills a large unmet need, and bridges a long-awaited knowledge gap among trainees, clinicians, scientists, nurses and technicians, earnestly engaged in this field. First of its kind text that covers both basic and clinical aspects, bridging the knowledge gap, and providing a bench to bedside approach for management of common disorders Discusses the latest concepts and basic principles of neurogastroenterology and motility, and how the gut and brain interact in the genesis of functional gastrointestinal and motility disorders Provides an illustrated and practical text on hot topics written by leading adult and pediatric gastroenterology experts across the globe Includes an accompanying more detailed web version of the text with free access to future podcasts