Download Handbook Of Polymer Applications In Medicine And Medical Devices Book PDF

Download full Handbook Of Polymer Applications In Medicine And Medical Devices books PDF, EPUB, Tuebl, Textbook, Mobi or read online Handbook Of Polymer Applications In Medicine And Medical Devices anytime and anywhere on any device. Get free access to the library by create an account, fast download and ads free. We cannot guarantee that every book is in the library.

Handbook of Polymer Applications in Medicine and Medical Devices

Handbook of Polymer Applications in Medicine and Medical Devices
  • Author : Kayvon Modjarrad,Sina Ebnesajjad
  • Publisher :Unknown
  • Release Date :2013-12-05
  • Total pages :368
  • ISBN : 9780323221696
GET BOOK HERE

Summary : While the prevalence of plastics and elastomers in medical devices is now quite well known, there is less information available covering the use of medical devices and the applications of polymers beyond medical devices, such as in hydrogels, biopolymers and silicones beyond enhancement applications, and few books in which these are combined into a single reference. This book is a comprehensive reference source, bringing together a number of key medical polymer topics in one place for a broad audience of engineers and scientists, especially those currently developing new medical devices or seeking more information about current and future applications. In addition to a broad range of applications, the book also covers clinical outcomes and complications arising from the use of the polymers in the body, giving engineers a vital insight into the real world implications of the devices they’re creating. Regulatory issues are also covered in detail. The book also presents the latest developments on the use of polymers in medicine and development of nano-scale devices. Gathers discussions of a large number of applications of polymers in medicine in one place Provides an insight into both the legal and clinical implications of device design Relevant to industry, academic and medical professionals Presents the latest developments in the field, including medical devices on a nano-scale

Handbook of Polymer Applications in Medicine and Medical Devices

Handbook of Polymer Applications in Medicine and Medical Devices
  • Author : André Colas,Jim Curtis
  • Publisher :Unknown
  • Release Date :2013-12-05
  • Total pages :368
  • ISBN : 9780128076699
GET BOOK HERE

Summary : Silicone materials have been widely used in medicine for over 60 years. Available in a variety of material types, they have unique chemical and physical properties that manifest in excellent biocompatibility and biodurability for many applications. Silicone elastomers have remarkably low glass-transition temperatures and maintain their flexibility over a wide temperature range, enabling them to withstand conditions from cold storage to steam autoclaving. They have high permeability to gases and many drugs, advantageous respectively in wound care or in transdermal drug delivery. They have low surface tension and remarkable chemical stability, enabling biocompatibility and biodurability in many long-term implant applications.

Handbook of Polymer Applications in Medicine and Medical Devices

Handbook of Polymer Applications in Medicine and Medical Devices
  • Author : Len Czuba
  • Publisher :Unknown
  • Release Date :2013-12-05
  • Total pages :368
  • ISBN : 9780128076644
GET BOOK HERE

Summary : This chapter will present a look at the medical device market with a particular focus on the materials of construction of devices and what we can expect in new products looking ahead. A deeper look at some other trends that have an effect on the direction of the medical device industry will be done. Finally, consideration will be given to a number of global factors that can have dramatic effects on our industry.

Handbook of Polymer Applications in Medicine and Medical Devices

Handbook of Polymer Applications in Medicine and Medical Devices
  • Author : Wei He,Roberto Benson
  • Publisher :Unknown
  • Release Date :2013-12-05
  • Total pages :368
  • ISBN : 9780128076668
GET BOOK HERE

Summary : Biomaterials are an indispensable element in improving human health and quality of life. Applications of biomaterials include diagnostics (gene arrays and biosensors), medical supplies (blood bags and surgical tools), therapeutic treatments (medical implants and devices), and emerging regenerative medicine (tissue-engineered skin and cartilage). Polymers, being organic, offer a versatility that is unmatched by metals and ceramics. The wide spectrum of physical, mechanical, and chemical properties provided by polymers has fueled the extensive research, development, and applications of polymeric biomaterials. The significance of polymers as biomaterials is reflected in the market size of medical polymers, estimated to be approximately $1 billion. Many of these polymers were initially developed as plastics, elastomers, and fibers for nonmedical industrial applications, but were later developed as biomedical-specific materials. With rapid growth in modern biology and interdisciplinary collaborative efforts, polymeric biomaterials are being fashioned into bioactive and biomimetic materials, with excellent biocompatibility.

Handbook of Polymer Applications in Medicine and Medical Devices

Handbook of Polymer Applications in Medicine and Medical Devices
  • Author : Vinny R. Sastri
  • Publisher :Unknown
  • Release Date :2013-12-05
  • Total pages :368
  • ISBN : 9780128076767
GET BOOK HERE

Summary : Over the past 2000 years, many devices have been developed and used in the mitigation and diagnosis of diseases. The materials used in these devices have ranged from stone, wood, metal, ceramics, and most recently plastics. Medical devices have also evolved in sophistication and complexity over time. With the formalization of the scientific method in the seventeenth century such devices became more prevalent [1]. Many medical devices were manufactured by doctors or small companies and sold directly to the public with no government standards or oversight. With the explosion of medical technology in the early twentieth century, several intermediaries had evolved between the medical device industry and the public. In 1879, Dr E.R. Squibb, in an address to the Medical Society of the State of New York, proposed the enactment of a national statute to regulate food and drugs [2]. It was not until 27 years later that the Food and Drug Act of 1906 was introduced into the Congress and signed into law by President Theodore Roosevelt [3]. At that time, devices that were harmful to human safety and health proliferated the market but regulation of medical devices by the Bureau of Chemistry (the precursor to the Food and Drug Administration—FDA) was limited to challenging commercial products only after they had been released into the market. Devices in the marketplace that were defective, adulterated, or misbranded were seized and the device manufacturers were prosecuted in a court of law, but only after the products were sold in the market and caused harm to the end users. Thus, there was a strong need for regulating the devices before they entered the marketplace. An FDA report [4], issued in September 1970, detailed as many as 10,000 injuries and 731 deaths from ineffective medical devices. The report recommended the formation of a regulatory system and body that would enforce the production and sale of safe and effective devices to the public. All medical devices already on the market would be inventoried and classified into a three-tiered system based on their criticality of end use. It also detailed requirements for records and reports, registration and inspection of establishments, and uniform quality assurance programs called good manufacturing practices (GMP). After much lobbying by the FDA, Senate bill SR 510, “The Medical Device Amendments of 1973” was introduced by Senator Edward M. Kennedy and was passed by the Senate in 1975. House bill HR 11124, introduced by Representative Paul Rogers, was passed by the House in 1976. These bills eventually became the Medical Device Amendments of 1976, and were signed into law by President Nixon. The Medical Device Amendments of 1976 became the basis for the medical device regulation in the United States to control and regulate the production of finished devices and thus the device manufacturers themselves.

Handbook of Polymer Applications in Medicine and Medical Devices

Handbook of Polymer Applications in Medicine and Medical Devices
  • Author : Laurence W. McKeen
  • Publisher :Unknown
  • Release Date :2013-12-05
  • Total pages :368
  • ISBN : 9780128076651
GET BOOK HERE

Summary : Medical devices range from simple devices, to test equipment, to implants. Plastics are used more and more in these devices, for weight, cost, and performance purposes. Examples of medical devices include surgical instruments, catheters, coronary stents, pacemakers, magnetic resonance imaging (MRI) machines, X-ray machines, prosthetic limbs, artificial hips/knees, surgical gloves, and bandages.

Handbook of Polymer Applications in Medicine and Medical Devices

Handbook of Polymer Applications in Medicine and Medical Devices
  • Author : Sina Ebnesajjad
  • Publisher :Unknown
  • Release Date :2013-12-05
  • Total pages :368
  • ISBN : 9780128076682
GET BOOK HERE

Summary : This chapter focuses on adhesives used in direct physiological contact in dental and medical procedures. Activity in both areas has been quite extensive outside the United States for decades. In contrast, adhesive use in medical devices, patches, and plasters has been ongoing in the United States for a long time. In the case of medical devices, adhesion is concerned with the joining of materials such as plastics, elastomers, textiles, metals, and ceramics, which are examined in other chapters of the present volume and are covered in various references [1–6], The coverage of this chapter is devoted to applications where to adhesives are in direct contact with tissues and other live organs.

Handbook of Polymer Applications in Medicine and Medical Devices

Handbook of Polymer Applications in Medicine and Medical Devices
  • Author : Zheng Zhang,Ophir Ortiz,Ritu Goyal,Joachim Kohn
  • Publisher :Unknown
  • Release Date :2013-12-05
  • Total pages :368
  • ISBN : 9780128076750
GET BOOK HERE

Summary : The design and development of tissue-engineered products has benefited from many years of clinical utilization of a wide range of biodegradable polymers. Newly developed biodegradable polymers and modifications of previously developed biodegradable polymers have enhanced the tools available for creating clinically important tissue-engineering applications. Insights gained from studies of cell-matrix interactions, cell-cell signaling, and organization of cellular components, are placing increased demands on medical implants to interact with the patient’s tissue in a more biologically appropriate fashion. Whereas in the twentieth century biocompatibility was largely equated with eliciting no harmful response, the biomaterials of the twenty first century will have to elicit tissue responses that support healing or regeneration of the patient’s own tissue. This chapter surveys the universe of those biodegradable polymers that may be useful in the development of medical implants and tissue-engineered products. Here, we distinguish between biologically derived polymers and synthetic polymers. The materials are described in terms of their chemical composition, breakdown products, mechanism of breakdown, mechanical properties, and clinical limitations. Also discussed are product design considerations in processing of biomaterials into a final form (e.g., gel, membrane, matrix) that will effect the desired tissue response.

Handbook of Polymer Applications in Medicine and Medical Devices

Handbook of Polymer Applications in Medicine and Medical Devices
  • Author : Sana S. Dastgheyb,John R. Eisenbrey
  • Publisher :Unknown
  • Release Date :2013-12-05
  • Total pages :368
  • ISBN : 9780128076736
GET BOOK HERE

Summary : Microbubbles are small (

Handbook of Polymer Applications in Medicine and Medical Devices

Handbook of Polymer Applications in Medicine and Medical Devices
  • Author : Justin M. Saul,David F. Williams
  • Publisher :Unknown
  • Release Date :2013-12-05
  • Total pages :368
  • ISBN : 9780128076743
GET BOOK HERE

Summary : Hydrogels are crosslinked polymeric networks containing hydrophilic groups that promote swelling due to interaction with water [1]. While hydrogels are heavily used in the field of regenerative medicine, their application to biomedical systems is not new. In fact, it has been suggested that they were truly the first polymer materials to be developed for use in man [2]. They have been in use for clinical applications since the 1960s, initially for use in ocular applications including contact lenses and intraocular lenses due to their favorable oxygen permeability and lack of irritation leading to inflammation and foreign body response, which was observed with other plastics [3]. Before the concept of tissue engineering and regenerative medicine had gained traction, hydrogels were used for cell encapsulation [4]. They have also been utilized extensively in the clinic for wound healing applications due to their oxygen permeability, high water content, and ability to shield wounds from external agents. Perhaps the largest research focus and utility of hydrogels has been found in their use as controlled release systems. This combination of controlled release and cell encapsulation has led to increasing uses of hydrogels in regenerative medicine applications.

Handbook of Polymer Applications in Medicine and Medical Devices

Handbook of Polymer Applications in Medicine and Medical Devices
  • Author : Zbigniew Nawrat
  • Publisher :Unknown
  • Release Date :2013-12-05
  • Total pages :368
  • ISBN : 9780128076705
GET BOOK HERE

Summary : An explosion in multidisciplinary research, combining mechanical, chemical, and electrical engineering with physiology and medicine, during the 1960s created huge advances in modern health care. In cardiovascular therapy, lifesaving implantable defibrillators, ventricular assist devices, catheter-based ablation devices, vascular stent technology, and cell and tissue engineering technologies have been introduced. The latest and leading technology presents robots intended to keep the surgeon in the most comfortable, dexterous, and ergonomic position during the entire procedure. The branch of the medical and rehabilitation robotics includes the manipulators and robots providing surgery, therapy, prosthetics, and rehabilitation. This chapter provides an overview of research in cardiac surgery devices.

Handbook of Polymer Applications in Medicine and Medical Devices

Handbook of Polymer Applications in Medicine and Medical Devices
  • Author : Paul Stoodley,Luanne Hall-Stoodley,Bill Costerton,Patrick DeMeo,Mark Shirtliff,Ellen Gawalt,Sandeep Kathju
  • Publisher :Unknown
  • Release Date :2013-12-05
  • Total pages :368
  • ISBN : 9780128076675
GET BOOK HERE

Summary : The initial design criteria in the choice of indwelling materials for medical and dental purposes may be pragmatic, and based on the necessary mechanical properties required to fashion a functional device. Orthopedic implants require strong materials for weight-bearing, and articulating surfaces such as joints require durability and resistance to wear. Stents and shunts require flexibility and patency, and sutures require a high tensile strength yet also must be flexible enough for intricate manipulation. As the devices became more sophisticated and developments in materials science provided more options for manufacture, implants are being used more frequently and with longer anticipated lifetimes. Concurrently, the design process increasingly incorporated biocompatibility and comfort into the design criteria. However, with longer lifetimes, the more frequent use of invasive surgical procedures involving indwelling devices and biologically-friendly materials, there has been a rise in the number of incidences of device-related infection. Urinary catheters have been estimated to account for 30% of all nosocomial infections [1]. Between 66 and 88% of these occur after urinary catheterization [2]. It is also reported that almost 100% of catheterized patients develop an infection in an openly draining indwelling catheter which has been in place for four days or more [2]. For some procedures, such as orthopedic joint arthroplasties, the diagnosed surgical site infection rates are relatively low (between 1% and 2%; [3]); however, the increasing number of patients undergoing joint-replacement surgery translates to large numbers of patients afflicted with the consequences of complicating infections per year. Furthermore, infection of artificial joints can be devastating, since oral or IV antibiotic therapy frequently fails to resolve the infection, with the only remaining course of action being surgical debridement or partial or total revision. These two examples, the first with very high numbers of patients but of lesser severity in terms of impact to the individual, and the second, low numbers but severe patient impact, reflect the incentive to pursue a third design criteria—that of infection resistance—into materials and devices [4]. In the following sections we will discuss the role of bacterial biofilms in infection, and the growing literature highlighting biofilms as an important cause of device-related infection.

Handbook of Polymer Applications in Medicine and Medical Devices

Handbook of Polymer Applications in Medicine and Medical Devices
  • Author : Steven M. Kurtz
  • Publisher :Unknown
  • Release Date :2013-12-05
  • Total pages :368
  • ISBN : 9780128076729
GET BOOK HERE

Summary : The orthopedic and biomaterials literature of the 1990s reflects an early academic curiosity in implant applications of polyaryletherketone (PAEK) biomaterials [1,2]. However, widespread commercial applications for PAEK biomaterials in the human body were first realized with cage implants intended to promote intervertebral body (interbody) fusion of the lumbar spine. Success of PAEK with interbody implants would later inspire applications in a broad variety of spinal implant applications, including posterior fusion, dynamic stabilization, and disc arthroplasty.

Handbook of Polymer Applications in Medicine and Medical Devices

Handbook of Polymer Applications in Medicine and Medical Devices
  • Author : Thomas C. Mort,Jeffrey P. Keck
  • Publisher :Unknown
  • Release Date :2013-12-05
  • Total pages :368
  • ISBN : 9780128076712
GET BOOK HERE

Summary : The earliest recorded use of airway manipulation with an artificial device dates back to early Roman civilization when Asclepiades performed a tracheostomy for laryngeal edema. Today it is clear that the role of the endotracheal tube (ETT) in medicine is as invaluable as that of any other medical device created to date. The establishment of a definitive airway via the ETT in both elective and emergency situations has allowed for the delivery of immediate life-sustaining therapies during resuscitation, the maintenance of oxygenation and ventilation in prolonged illness, and the (temporary) delivery of inhaled anesthesia [1]. This chapter begins with a brief history of the development of the ETT. It describes the various ETTs available along with their indications for use and respective limitations. It reviews basic airway anatomy with regard to ETT placement, proper positioning and stabilization of the ETT, and complications attributed to its use. Finally, it addresses respiratory care of the intubated and mechanically ventilated patient.

Handbook of Active Materials for Medical Devices

Handbook of Active Materials for Medical Devices
  • Author : Andres Diaz Lantada
  • Publisher :Unknown
  • Release Date :2011-09-28
  • Total pages :350
  • ISBN : 9789814303354
GET BOOK HERE

Summary : This book covers biodevices, mainly implantable or quirurgical, for the diagnosis or treatment of different pathologies, which benefit from the use of active materials as sensors or actuators. Such active or "intelligent" materials are capable of responding in a controlled way to different external physical or chemical stimuli by changing some of their properties. These materials can be used to design and develop sensors, actuators, and multifunctional systems with a large number of applications for developing biodevices and medical appliances. Current work on these fields entails problems related to synthesis, characterization, modeling, simulation, processing, and prototyping technologies, as well as device testing and validation, all of which are treated in depth in this book, for the several types of active or intelligent materials covered. The research presented in this book helps further development of medical devices, based on the additional functionalities that the use of active or "intelligent" materials, both as sensors and actuators, supplies. The main results exposed may help with the industrial expansion of this kind of materials as part of more complex systems.

Materials for Medical Application

Materials for Medical Application
  • Author : Robert B. Heimann
  • Publisher :Unknown
  • Release Date :2020-08-24
  • Total pages :637
  • ISBN : 9783110619249
GET BOOK HERE

Summary : This book gives an introduction to the highly interdisciplinary field of biomaterials. It concisely summarizes properties, synthesis and modification of materials such as metals, ceramics, polymers or composites. Characterization, in vitro and in vivo testing as well as a selection of various applications are also part of this inevitable guide.

Multilayer Flexible Packaging

Multilayer Flexible Packaging
  • Author : John R. Wagner, Jr.
  • Publisher :Unknown
  • Release Date :2016-03-29
  • Total pages :410
  • ISBN : 9780323477185
GET BOOK HERE

Summary : Multilayer Flexible Packaging, Second Edition, provides a thorough introduction to the manufacturing and applications of flexible plastic films, covering materials, hardware and processes, and multilayer film designs and applications. The book gives engineers and technicians a better understanding of the capability and limitations of multilayer flexible films and how to use them to make effective packaging. It includes contributions from world renowned experts and is fully updated to reflect the rapid advances made in the field since 2009, also including an entirely new chapter on the use of bio-based polymers in flexible packaging. The result is a practical, but detailed reference for polymeric flexible packaging professionals, including product developers, process engineers, and technical service representatives. The materials coverage includes detailed sections on polyethylene, polypropylene, and additives. The dies used to produce multilayer films are explored in the hardware section, and the process engineering of film manufacture is explained, with a particular focus on meeting specifications and targets. In addition, a new chapter has been added on regulations for food packaging – including both FDA and EU regulations. Provides a complete introduction to multilayer flexible packaging, assisting plastics practitioners with the development, design, and manufacture of flexible packaging for food, cosmetics, pharmaceuticals, and more Presents thorough, well-written, and up-to-date reviews of the current technology by experts in the field, making this an essential reference for any engineer or manager Includes discussion and analysis of the latest rules and regulations governing food packaging

The Effect of Temperature and other Factors on Plastics and Elastomers

The Effect of Temperature and other Factors on Plastics and Elastomers
  • Author : Laurence W. McKeen
  • Publisher :Unknown
  • Release Date :2014-04-15
  • Total pages :752
  • ISBN : 9780323310178
GET BOOK HERE

Summary : This reference guide brings together a wide range of critical data on the effect of temperature on plastics and elastomers, enabling engineers to make optimal material choices and design decisions. The effects of humidity level and strain rate on mechanical and electrical properties are also covered. The data are supported by explanations of how to make use of the data in real world engineering contexts. High (and low) temperatures can have a significant impact on plastics processing and applications, particularly in industries such as automotive, aerospace, oil and gas, packaging, and medical devices, where metals are increasingly being replaced by plastics. Additional plastics have also been included for polyesters, polyamides and others where available, including polyolefins, elastomers and fluoropolymers. Entirely new sections on biodegradable polymers and thermosets have been added to the book. The level of data included – along with the large number of graphs and tables for easy comparison – saves readers the need to contact suppliers, and the selection guide has been fully updated, giving assistance on the questions which engineers should be asking when specifying materials for any given application. Trustworthy, current thermal data and best practice guidance for engineers and materials scientists in the plastics industry More than 1,000 graphs and tables allow for easy comparison between plastics Entirely new sections added on biopolymers and thermosets.

The Science and Technology of Flexible Packaging

The Science and Technology of Flexible Packaging
  • Author : Barry A Morris
  • Publisher :Unknown
  • Release Date :2016-09-01
  • Total pages :744
  • ISBN : 9780323243254
GET BOOK HERE

Summary : The Science and Technology of Flexible Packaging: Multilayer Films from Resin and Process to End Use provides a comprehensive guide to the use of plastic films in flexible packaging, covering scientific principles, properties, processes, and end use considerations. The book brings the science of multilayer films to the practitioner in a concise and impactful way, presenting the fundamental understanding required to improve product design, material selection, and processes, and includes information on why one material is favored over another for a particular application, or how the film or coating affects material properties. Detailed descriptions and analysis of the key properties of packaging films are provided from both an engineering and scientific perspective. End-use effects are also covered in detail, providing key insights into the way the products being packaged influence film properties and design. The book bridges the gap between key scientific literature and the practical challenges faced by the flexible packaging industry, providing essential scientific insights, best practice techniques, environmental sustainability information, and key principles of structure design to enable engineers and scientists to deliver superior products with reduced development time and cost. Provides essential information on all aspects of multilayer films in flexible packaging Aids in material selection and processing, shortening development times and delivering stronger products Bridges the gap between scientific principles and key challenges in the packaging industry, with practical explanations to assist practitioners in overcoming those challenges

Plastics in Medical Devices

Plastics in Medical Devices
  • Author : Vinny R. Sastri
  • Publisher :Unknown
  • Release Date :2010-03-05
  • Total pages :352
  • ISBN : 9780815520283
GET BOOK HERE

Summary : No book has been published that gives a detailed description of all the types of plastic materials used in medical devices, the unique requirements that the materials need to comply with and the ways standard plastics can be modified to meet such needs. This book will start with an introduction to medical devices, their classification and some of the regulations (both US and global) that affect their design, production and sale. A couple of chapters will focus on all the requirements that plastics need to meet for medical device applications. The subsequent chapters describe the various types of plastic materials, their properties profiles, the advantages and disadvantages for medical device applications, the techniques by which their properties can be enhanced, and real-world examples of their use. Comparative tables will allow readers to find the right classes of materials suitable for their applications or new product development needs.

Proceedings of 5th International Conference on Advanced Manufacturing Engineering and Technologies

Proceedings of 5th International Conference on Advanced Manufacturing Engineering and Technologies
  • Author : Vidosav Majstorovic,Zivana Jakovljevic
  • Publisher :Unknown
  • Release Date :2017-04-22
  • Total pages :475
  • ISBN : 9783319564302
GET BOOK HERE

Summary : This book presents the proceedings from the 5th NEWTECH conference (Belgrade, Serbia, 5–9 June 2017), the latest in a series of high-level conferences that bring together experts from academia and industry in order to exchange knowledge, ideas, experiences, research results, and information in the field of manufacturing. The range of topics addressed is wide, including, for example, machine tool research and in-machine measurements, progress in CAD/CAM technologies, rapid prototyping and reverse engineering, nanomanufacturing, advanced material processing, functional and protective surfaces, and cyber-physical and reconfigurable manufacturing systems. The book will benefit readers by providing updates on key issues and recent progress in manufacturing engineering and technologies and will aid the transfer of valuable knowledge to the next generation of academics and practitioners. It will appeal to all who work or conduct research in this rapidly evolving field.