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Handbook on the Toxicology of Metals

Handbook on the Toxicology of Metals
  • Author : Monica Nordberg,Gunnar F. Nordberg,Bruce A. Fowler,Lars Friberg
  • Publisher :Unknown
  • Release Date :2011-04-28
  • Total pages :1024
  • ISBN : 0080546102
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Summary : Handbook of the Toxicology of Metals is the standard reference work for physicians, toxicologists and engineers in the field of environmental and occupational health. This new edition is a comprehensive review of the effects on biological systems from metallic elements and their compounds. An entirely new structure and illustrations represent the vast array of advancements made since the last edition. Special emphasis has been placed on the toxic effects in humans with chapters on the diagnosis, treatment and prevention of metal poisoning. This up-to-date reference provides easy access to a broad range of basic toxicological data and also gives a general introduction to the toxicology of metallic compounds. * Covers up-to-date toxicological information on 31 metallic elements and their compounds, each in a separate chapter * New chapters on general chemistry, biological monitoring and biomarkers, essential metals, principles for prevention of the toxic effects of metals, and more

Handbook on the Toxicology of Metals

Handbook on the Toxicology of Metals
  • Author : Gunnar F. Nordberg,Bruce A. Fowler,Monica Nordberg
  • Publisher :Unknown
  • Release Date :2014-08-07
  • Total pages :1542
  • ISBN : 9780123973399
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Summary : Handbook on the Toxicology of Metals, Fourth Edition bridges the gap between established knowledgebase and new advances in metal toxicology to provide one essential reference for all those involved in the field. This book provides comprehensive coverage of basic toxicological data, emphasizing toxic effects primarily in humans, but also those of animals and biological systems in vitro. The fourth edition also contains several new chapters on important topics such as nanotoxicology, metals in prosthetics and dental implants, gene-environment interaction, neurotoxicology, metals in food, renal, cardiovascular, and diabetes effects of metal exposures and more. Volume I covers “General Considerations and Volume II is devoted to “Specific Metals. A multidisciplinary resource with contributions from internationally-recognized experts, the fourth edition of the Handbook on the Toxicology of Metals is a prominent and indispensable reference for toxicologists, physicians, pharmacologists, engineers, and all those involved in the toxicity of metals. Contains 61 peer reviewed chapters dealing with the effects of metallic elements and their compounds on biological systems Includes information on sources, transport and transformation of metals in the environment and on certain aspects of the ecological effects of metals to provide a basis for better understanding of the potential for adverse effects on human health Covers the toxicology of metallic nanomaterials in a new comprehensive chapter Metal toxicology in developing countries is dealt with in another new chapter emphasizing the adverse effects on human health by the inadequate handling of "ewaste Other new chapters in the 4th edition include: Toxic metals in food; Toxicity of metals released from medical devices; Gene-environment interactions; Neurotoxicology of metals; Cardiovascular disease; Renal effects of exposure to metals; Gold and gold mining; Iridium; Lanthanum; Lithium and Rhodium

Handbook on the Toxicology of Metals: Specific metals

Handbook on the Toxicology of Metals: Specific metals
  • Author : Lars Friberg,Gunnar Nordberg,Velimir B. Vouk
  • Publisher :Unknown
  • Release Date :1986
  • Total pages :704
  • ISBN : 0444904425
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Summary : Chapters on specific metals include physical and chemical properties, methods and problems of analysis, production and uses, environmental levels and exposures, metabolism, levels in tissues and biological fluids, effects and dose-response relationships, carcinogenicity, mutagenicity, teratogenicity and preventative measures, diagnosis, treatment and prognosis.

Handbook on the Toxicology of Metals: General aspects

Handbook on the Toxicology of Metals: General aspects
  • Author : Lars Friberg,Gunnar Nordberg,Velimir B. Vouk
  • Publisher :Unknown
  • Release Date :1986
  • Total pages :1162
  • ISBN : 0444904131
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Summary : Chapters on specific metals include physical and chemical properties, methods and problems of analysis, production and uses, environmental levels and exposures, metabolism, levels in tissues and biological fluids, effects and dose-response relationships, carcinogenicity, mutagenicity, teratogenicity and preventative measures, diagnosis, treatment and prognosis.

Metal Toxicology Handbook

Metal Toxicology Handbook
  • Author : Debasis Bagchi,Manashi Bagchi
  • Publisher :Unknown
  • Release Date :2020-11-19
  • Total pages :490
  • ISBN : 9780429795749
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Summary : Heavy metals and metalloids, singly or in combination, induce toxic manifestations either through acute or chronic pathology. In particular, long-term chronic exposure to diverse heavy metals and metalloids to humans and animals can lead to numerous physical, muscular, neurological, nephrological, and diverse degenerative diseases and dysfunctions, including multiple sclerosis, muscular dystrophy, Parkinson’s and Alzheimer’s diseases, cardiovascular disorders, and several others. Recognized heavy metals such as lead, mercury, arsenic, cadmium, thallium, and hexavalent chromium are known for enormous toxicity. The immediate vital signs of acute heavy metal exposure include nausea, vomiting, diarrhea, and acute abdominal pain. Mercury has been identified as the most toxic heavy metal, and mercury poisoning is known as acrodynia or pink disease. Similarly, lead, another toxic heavy metal, was at one time an integral part of painting. Metal Toxicology Handbook further explains and discusses the varying attributes of metals, discussing toxicity, safety, and proper human utilization of metals. Beginning with a broad overview of metals, metalloids, redox biology, and neurodegeneration and going further into the roles, benefits, and toxicity of metals with each section, the text contains 28 chapters from eminent researchers and scientists in their respective fields and is a must-have for anyone researching the potential toxicity in metals. Key Features Discusses the pathology of metal toxicity Highlights the benefits of metals Explains the mechanism and salient features of restoring metabolic homeostasis Highlights dose-dependent beneficial and adverse effects of vanadium safety and toxicity The initial introductory section provides a broad overview of metals, metalloids, redox biology, and neurodegeneration. The second section discusses the pathology of metal toxicity in two chapters, while the third section highlights the mechanism and salient features of restoring metabolic homeostasis in two chapters. The fourth section demonstrates the aspect of radionuclides toxicity. In a change of pace, the fifth section discusses the benefits of metals in four chapters. The sixth section, titled "Toxic Manifestations by Diverse Heavy Metals and Metalloids," provides fourteen chapters that discuss the toxicological mechanism and manifestation of individual metals. The editors have crafted a commentary titled "A Treatise on Metal Toxicity" and summarized a vivid scenario of metal toxicity and its consequences.

Risk Assessment for Human Metal Exposures

Risk Assessment for Human Metal Exposures
  • Author : Gunnar F. Nordberg,Bruce A. Fowler
  • Publisher :Unknown
  • Release Date :2018-08-21
  • Total pages :348
  • ISBN : 9780128042687
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Summary : Risk Assessment for Human Metal Exposures: Mode of Action and Kinetic Approaches examines the current principles of risk assessment in human metal exposures, with a focus on Mode of Action(MOA), Toxicokinetic and Toxicodynamic (TKTD) considerations, and computer models. Derived from the highly respected Handbook on the Toxicology of Metals, Fourth Edition (2014), the book summarizes principles and methods and provides examples of how MOA –TKTD can be used. In addition, it presents tactics on how information generated by such methods can be confirmed by epidemiological data. Furthermore, it demonstrates how epidemiological data can be confirmed and evaluated by the examined models and considerations. This resource uniquely integrates several important topics, such as risk assessment, characterization, management and communication—the classic risk assessment paradigm—with mode of action, TKTD, and epidemiology, all topics related to human exposure. Written by pioneers in the field, this book is an essential reference for researchers, students and technicians in toxicology and risk assessment. Covers fundamental risk assessment concerns for the effects of metals on human health Provides an easy-to-use structure to quickly locate specific methods Uses case studies to illustrate the methods and theories described Written to be understood by students, researchers and industry workers who need to conduct risk assessment in metals and human health

Handbook of Arsenic Toxicology

Handbook of Arsenic Toxicology
  • Author : Swaran Jeet Singh Flora
  • Publisher :Unknown
  • Release Date :2014-12-26
  • Total pages :752
  • ISBN : 9780124199552
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Summary : Throughout history, arsenic has been used as an effective and lethal poison. Today, arsenic continues to present a real threat to human health all over the world, as it contaminates groundwater and food supplies. Handbook of Arsenic Toxicology presents the latest findings on arsenic, its chemistry, its sources and its acute and chronic effects on the environment and human health. The book takes readings systematically through the target organs, before detailing current preventative and counter measures. This reference enables readers to effectively assess the risks related to arsenic, and provide a comprehensive look at arsenic exposure, toxicity and toxicity prevention. Brings together current findings on the effects of arsenic on the environment and human health Includes state-of-the-art techniques in arsenic toxicokinetics, speciation and molecular mechanisms Provides all the information needed for effective risk assessment, prevention and countermeasure

Toxicology of Metals

Toxicology of Metals
  • Author : N. Ballatori
  • Publisher :Unknown
  • Release Date :1995
  • Total pages :467
  • ISBN : 0387582819
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Summary :

Handbook of Human Toxicology

Handbook of Human Toxicology
  • Author : Edward J. Massaro
  • Publisher :Unknown
  • Release Date :1997-07-09
  • Total pages :1136
  • ISBN : 9781439805756
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Summary : Covering some of the most important topics in modern toxicology, the Handbook of Human Toxicology is a unique and valuable addition to the current literature. It addresses issues, answers questions, and provides data related to. Within each of these five major sections are several carefully selected topics that reflect the current state of human to

Toxicology of Metals

Toxicology of Metals
  • Author : Louis W. Chang
  • Publisher :Unknown
  • Release Date :1996-08-02
  • Total pages :1232
  • ISBN : 0873718038
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Summary : This volume offers the most comprehensive presentation available on metal toxicology. It discusses not only metals but also the toxic endpoints, such as neurotoxicity, renal toxicity, and cancer induction. Chapters are written by experts in their respective fields, focusing on carcinogenesis and human exposures and highlighting the major aspects and issues of toxicity in general.

Metal Toxicology

Metal Toxicology
  • Author : Robert A. Goyer
  • Publisher :Unknown
  • Release Date :2016-01-22
  • Total pages :525
  • ISBN : 9781483288567
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Summary : Metal Toxicology addresses the effects of metals on human health, as well as their mechanisms of toxicity. Unlike most books on metal toxicity which are organized by individual metals, this book is arranged inan organ-by-organ basis. It deals with unifying mechanisms of metal toxicity within a given tissue, and with exposure of a tissue to more than one metal at a time. Unique aspect of organ-specific orientation Written by leading authorities in metal toxicology Chapters of special interest include Risk Assessment, Emerging Technologies, and Molecular Biological Techniques Serves as an excellent sourcebook of generalized information on metal toxicology, allowing for specific tissue-system referencing

Haschek and Rousseaux's Handbook of Toxicologic Pathology

Haschek and Rousseaux's Handbook of Toxicologic Pathology
  • Author : Wanda M. Haschek,Colin G. Rousseaux,Matthew A. Wallig
  • Publisher :Unknown
  • Release Date :2013-05-01
  • Total pages :3054
  • ISBN : 9780124157651
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Summary : Haschek and Rousseaux's Handbook of Toxicologic Pathology is a key reference on the integration of structure and functional changes in tissues associated with the response to pharmaceuticals, chemicals and biologics. The 3e has been expanded by a full volume, and covers aspects of safety assessment not discussed in the 2e. Completely revised with many new chapters, it remains the most authoritative reference on toxicologic pathology for scientists and researchers studying and making decisions on drugs, biologics, medical devices and other chemicals, including agrochemicals and environmental contaminants. New topics include safety assessment, the drug life cycle, risk assessment, communication and management, carcinogenicity assessment, pharmacology and pharmacokinetics, biomarkers in toxicologic pathology, quality assurance, peer review, agrochemicals, nanotechnology, food and toxicologic pathology, the environment and toxicologic pathology and more. Provides new chapters and in-depth discussion of timely topics in the area of toxicologic pathology and broadens the scope of the audience to include toxicologists and pathologists working in a variety of settings Offers high-quality and trusted content in a multi-contributed work written by leading international authorities in all areas of toxicologic pathology Features hundreds of full color images in both the print and electronic versions of the book to highlight difficult concepts with clear illustrations

Handbook of Metal-Microbe Interactions and Bioremediation

Handbook of Metal-Microbe Interactions and Bioremediation
  • Author : Surajit Das,Hirak Ranjan Dash
  • Publisher :Unknown
  • Release Date :2017-04-07
  • Total pages :813
  • ISBN : 9781498762434
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Summary : Around the World, metal pollution is a major problem. Conventional practices of toxic metal removal can be ineffective and/or expensive, delaying and exacerbating the crisis. Those communities dealing with contamination must be aware of the fundamentals advances of microbe-mediated metal removal practices because these methods can be easily used and require less remedial intervention. This book describes innovations and efficient applications for metal bioremediation for environments polluted by metal contaminates.

Fish Physiology: Homeostasis and Toxicology of Essential Metals

Fish Physiology: Homeostasis and Toxicology of Essential Metals
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2011-06-28
  • Total pages :520
  • ISBN : 9780123786371
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Summary : Homeostasis and Toxicology of Essential Metals synthesizes the explosion of new information on the molecular, cellular, and organismal handling of metals in fish in the past 15 years. These elements are no longer viewed by fish physiologists as "heavy metals" that kill fish by suffocation, but rather as interesting moieties that enter and leave fish by specific pathways, which are subject to physiological regulation. The metals featured in this volume are those about which there has been most public and scientific concern, and therefore are those most widely studied by fish researchers. Metals such as Cu, Zn, Fe, Ni, Co, Se, Mo and Cr are either proven to be or are strongly suspected to be essential in trace amounts, yet are toxic in higher doses. The companion volume, Homeostasis and Toxicology of Non-Essential Metals, Volume 31B, covers metals that have no known nutritive function in fish at present, but which are toxic at fairly low levels, such as Ag, Al, Cd, Pb, Hg, As, Sr, and U. In addition, three chapters in Volumes 31A and 31B on Basic Principles (Chapter 1, 31A), Field Studies and Ecological Integration (Chapter 9, 31A) and Modeling the Physiology and Toxicology of Metals (Chapter 9, 31B) act as integrative summaries and make these two volumes a vital set for readers. All major essential metals of interest are covered in metal-specific chapters Each metal-specific chapter is written by fish physiologists/toxicologists who are recognized authorities for that metal A common format is featured throughout this two volume edition

Handbook of Copper Pharmacology and Toxicology

Handbook of Copper Pharmacology and Toxicology
  • Author : Edward J. Massaro
  • Publisher :Unknown
  • Release Date :2002-07-01
  • Total pages :608
  • ISBN : 9781592592883
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Summary : Edward J. Massaro and a panel of leading biomedical researchers and clinical practitioners review, in-depth, the status of our current knowledge concerning the biochemistry of copper in general and its role in health and disease in particular. Drawing on the wealth of new information emerging from the molecular biology revolution, these experts survey the most important research areas of copper pharmacology and toxicology, including copper proteins and transport, copper toxicity and therapeutics, and copper metabolism and homeostasis. They also discuss the molecular pathogenesis of copper in a variety of metabolic diseases, Menkes and Wilson's diseases and occipital horn syndrome, as well as the role of copper in Parkinson's disease, prion disease, familial amytrophic lateral sclerosis (ALS), and Alzheimer's disease.

Mercury — Cadmium — Lead Handbook for Sustainable Heavy Metals Policy and Regulation

Mercury — Cadmium — Lead Handbook for Sustainable Heavy Metals Policy and Regulation
  • Author : Gerrit H. Vonkeman,I. Thornton,Z. Makuch
  • Publisher :Unknown
  • Release Date :2001-12-31
  • Total pages :525
  • ISBN : 1402002246
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Summary : Although this is a handbook for policy and regulation, the major part of it is filled with data on the three heavy metals that served as examples: mercury, cadmium and lead. Their stocks, productions, prices, trade flows, uses and applications, recovery and recycling, as well as their (eco)toxicological characteristics have been collected and presented to their fullest extent. In addition, they are thoroughly analysed for consistency, future developments and trends and, of course, their consequences for sustainable development and future policy and regulation. The second part, on policy and regulation, begins with an extensive and fundamental consideration on the characteristics of a sustainable heavy metals policy, whereby innovative policy tools are developed. In many aspects, these considerations are also valid for other metals and even non-metallic persistent substances. Addressing the European Union in particular, its policy-making structure and practice are critically analysed, in order to develop feasible and viable guidelines for long-, medium- and short-term EU policy measures. The results of this exercise are then applied to the three heavy metals. In each of these three chapters, all existing EU measures are presented in detail and confronted with better practices elsewhere, resulting in many suggestions and recommendations for the future. In the last chapter, the main conclusions and recommendations are carefully summarised. Together with a very extended table of contents, this makes the book easily accessible, in spite of its volume. This Handbook is a must for policy-makers and administrators at all levels, as well as for their counterparts in a wide variety of industries. In addition, it is well-suited for environmental science courses at academic or higher professional level.

Handbook of Food Toxicology

Handbook of Food Toxicology
  • Author : S.S. Deshpande
  • Publisher :Unknown
  • Release Date :2002-08-29
  • Total pages :920
  • ISBN : 9780203908969
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Summary : From health and economic consequences to exposure assessment and detoxification, this reference comprehensively covers the formation, characteristics, and control of various toxins that occur in the production, storage, handling, and preparation of food. The author discusses toxin sources, mechanisms, routes of exposure and absorption, and their chemical and biochemical components to prevent contamination of food products and reduce epidemics of foodborne disease. The book contains more than 3000 references to facilitate further research, as well as recent guidelines from the FDA and World Health Organization regarding food hygiene and safety.

Handbook of Chemicals and Safety

Handbook of Chemicals and Safety
  • Author : T.S.S. Dikshith
  • Publisher :Unknown
  • Release Date :2016-04-19
  • Total pages :531
  • ISBN : 1439820619
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Summary : A host of chemical substances have become essential parts of human activities and requirements for societal development. Any kind of misuse and/or negligence in handling these substances can cause health disorders, poisoning, and fatalities among unprotected workers and members of the public exposed to contaminated food, water, and air. Carefully o

Fundamentals of Toxicology

Fundamentals of Toxicology
  • Author : PK Gupta
  • Publisher :Unknown
  • Release Date :2016-08-26
  • Total pages :422
  • ISBN : 9780128054031
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Summary : Fundamentals of Toxicology: Essential Concepts and Applications provides a crisp, easy-to-understand overview of the most important concepts, applications, and ideas needed to learn the basics of toxicology. Written by a pre-eminent toxicologist with over five decades of teaching experience, this comprehensive resource offers the hands-on knowledge needed for a strong foundation in the wide field of toxicology. Fundamentals of Toxicology includes a clear structure divided into five units to assist learning and understanding. The first unit provides extensive coverage on the background of toxicology including commonly used definitions and historical perspective, while following units cover: basic concepts; regulatory requirements and good laboratory practices, including types of toxicology testing and evaluation; toxic agents and adverse effects on health; and analytical, forensic, and diagnostic toxicology. This is an essential book for advanced students in toxicology and across the biomedical sciences, life sciences, and environmental sciences who want to learn the concepts of toxicology, as well as early researchers needing to refresh outside of their specialty. Explains the essential concepts of toxicology in a clear fashion Provides in-depth coverage of testing protocols, common drugs, chemicals, and laboratory-based diagnostic and analytical toxicology Explores the history, foundations, and most recent concepts of toxicology Serves as an essential reference for advanced students in toxicology and across the biomedical, life, and environmental sciences who want to learn the concepts of toxicology

Handbook of Toxic Properties of Monomers and Additives

Handbook of Toxic Properties of Monomers and Additives
  • Author : Victor O. Sheftel
  • Publisher :Unknown
  • Release Date :1995-04-18
  • Total pages :384
  • ISBN : 1566700752
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Summary : Covering nearly 800 potential food and water contaminants, this comprehensive handbook is a complete encyclopedia of the toxic effects of plastic ingredients. It is international in scope, covering all available toxicological data that fits existing requirements, including Russian toxicology data previously unknown to the West. The handbook will be helpful when evaluating toxic properties of plastic materials currently in use. It also provides a perspective on materials containing previously investigated ingredients. The handbook extends beyond the realm of toxicology by including information on a number of the widespread food and water contaminants, heavy metals, and solvents. It will also be helpful when evaluating toxic properties not only of existing materials but also of future materials that contain previously investigated ingredients.

Heavy Metals in the Environment

Heavy Metals in the Environment
  • Author : Lawrence K. Wang,Jiaping Paul Chen,Yung-Tse Hung,Nazih K. Shammas
  • Publisher :Unknown
  • Release Date :2009-06-23
  • Total pages :516
  • ISBN : 1420073192
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Summary : A successful modern heavy metal control program for any industry will include not only traditional water pollution control, but also air pollution control, soil conservation, site remediation, groundwater protection, public health management, solid waste disposal, and combined industrial-municipal heavy metal waste management. In fact, it should be a total environmental control program. Comprehensive in scope, Heavy Metals in the Environment provides technical and economical information on the development of a feasible total heavy metal control program that can benefit industry and local municipalities. The book discusses the importance and contamination of metals such as lead, chromium, cadmium, zinc, copper, nickel, iron, and mercury. It covers important research of metals in the environment, the processes and mechanisms for metals control and removal, the environmental behavior and effects of engineered metal and metal oxide nanoparticles, environmental geochemistry of high arsenic aquifer systems, nano-technology applications in metal ion adsorption, biosorption of metals, and heavy metal removal by expopolysaccharide-producing cyanobacteria. The authors delineate technologies for metals treatment and management, metal bearing effluents, metal-contaminated solid wastes, metal finishing industry wastes and brownfield sites, and arsenic-contaminated groundwater streams. They also discuss control, treatment, and management of metal emissions from motor vehicles. The authors reflect the breadth of the field and draw on personal experiences to provide an in-depth presentation of environmental pollution sources, waste characteristics, control technologies, management strategies, facility innovations, process alternatives, costs, case histories, effluent standards, and future trends for each industrial or commercial operation. The methodologies and technologies discussed are directly applicable to the waste management problems that must be met in all industries.