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Hematopoietic Stem Cell Transplantation

Hematopoietic Stem Cell Transplantation
  • Author : Jennifer Treleaven,Austin John Barrett
  • Publisher :Unknown
  • Release Date :2009
  • Total pages :555
  • ISBN : 0443101477
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Summary : A guide to the practice of stem cell transplantation, its status in the treatment of various disorders and the problems that arise after transplantation, aimed at the whole transplant team. An up to date guide to best practice in the use of stem cell transplantation, covering current status in the treatment of malignant and non-malignant conditions, practical aspects and problems such as infection and graft versus host disease. Has a practical, accessible approach with free use of algorithms, list tables. Aimed at the whole transplant team - this is an interdisciplinary field. International contributor team with editors in the UK and USA. Illustrated in colour throughout.

Stem Cells in Clinical Practice and Tissue Engineering

Stem Cells in Clinical Practice and Tissue Engineering
  • Author : Rakesh Sharma
  • Publisher :Unknown
  • Release Date :2018-05-02
  • Total pages :352
  • ISBN : 9781789230109
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Summary : Stem Cells in Clinical Practice and Tissue Engineering is a concise book on applied methods of stem cell differentiation and optimization using tissue engineering methods. These methods offer immediate use in clinical regenerative medicine. The present volume will serve the purpose of applied stem cell differentiation optimization methods in clinical research projects, as well as be useful to relatively experienced stem cell scientists and clinicians who might wish to develop their stem cell clinical centers or research labs further. Chapters are arranged in the order of basic concepts of stem cell differentiation, clinical applications of pluripotent stem cells in skin, cardiac, bone, dental, obesity centers, followed by tissue engineering, new materials used, and overall evaluation with their permitted legal status.

The European Blood and Marrow Transplantation Textbook for Nurses

The European Blood and Marrow Transplantation Textbook for Nurses
  • Author : Michelle Kenyon,Aleksandra Babic
  • Publisher :Unknown
  • Release Date :2018-03-14
  • Total pages :311
  • ISBN : 9783319500263
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Summary : This book is open access under a CC BY 4.0 license. This textbook, endorsed by the European Society for Blood and Marrow Transplantation (EBMT), provides adult and paediatric nurses with a full and informative guide covering all aspects of transplant nursing, from basic principles to advanced concepts. It takes the reader on a journey through the history of transplant nursing, including essential and progressive elements to help nurses improve their knowledge and benefit the patient experience, as well as a comprehensive introduction to research and auditing methods. This new volume specifically intended for nurses, complements the ESH-EBMT reference title, a popular educational resource originally developed in 2003 for physicians to accompany an annual training course also serving as an educational tool in its own right. This title is designed to develop the knowledge of nurses in transplantation. It is the first book of its kind specifically targeted at nurses in this specialist field and acknowledges the valuable contribution that nursing makes in this area. This volume presents information that is essential for the education of nurses new to transplantation, while also offering a valuable resource for more experienced nurses who wish to update their knowledge.

Blood and Marrow Stem Cell Transplantation

Blood and Marrow Stem Cell Transplantation
  • Author : Susan Ezzone,Kim Schmit-Pokorny
  • Publisher :Unknown
  • Release Date :2007
  • Total pages :521
  • ISBN : 076374719X
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Summary : Blood and Marrow Stem Cell Transplantation, Third Edition serves as a convenient reference for oncology nurses caring for blood and marrow stem cell transplantation recipients. The Third Edition has been updated and revised to reflect the most current research related to the past, present, and future of blood and marrow stem cell transplants. This resource covers everything from preparing for transplantation surgery, to recovery-related issues and delayed outcomes. Basic background information on transplantation procedures and processes are provided, along with in-depth coverage of pulmonary, cardiac, renal and hepatic, neurologic, and hematologic effects. A chapter devoted to controversial ethical issues is also provided. Blood and Marrow Stem Cell Transplantation, Third Edition presents complete, up-to-date coverage of the transplantation process from beginning to end.

Hematopoietic Stem Cell Transplantation

Hematopoietic Stem Cell Transplantation
  • Author : Susan Ezzone
  • Publisher :Unknown
  • Release Date :2012-10
  • Total pages :326
  • ISBN : 193586419X
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Summary : Since the publication of the first edition of this book in 2004, the specialty of hematopoietic stem cell transplantation (HSCT) has continued to progress as a treatment option for many diseases. Indications for the use of autologous, syngeneic, and allogeneic transplantation continue to expand. The second edition of Hematopoietic Stem Cell Transplantation: A Manual for Nursing Practice presents the most up-to-date information regarding the use of HSCT. Chapter topics include an overview of hematopoiesis and immunology, basic concepts of transplantation, stem cell collection, course of transplant treatment and acute complications, acute and chronic graft-versus-host disease, various complications from gastrointestinal to neurologic, relapse, long-term care and survivorship, ethics, and much more.

Hematopoietic Stem Cell Transplantation

Hematopoietic Stem Cell Transplantation
  • Author : Kim Schmit-Pokorny,Seth Eisenberg
  • Publisher :Unknown
  • Release Date :2020
  • Total pages :229
  • ISBN : 1635930413
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Summary : "Hematopoietic stem cell transplantation (HSCT) has evolved from primary use in hematologic malignancies and nonmalignant disease and solid tumors into a treatment option for many other diseases, and indications for HSCT continue to expand. The new edition of this manual provides comprehensive information on the ever-evolving specialty of HSCT, providing nurses and other practitioners with in-depth information on the entire HSCT process, from stem cell mobilization, collection, and infusion to potential complications and long-term effects. It also includes chapters on current research, emerging therapies, ethics, HSCT program development, and professional practice issues"--

The EBMT Handbook

The EBMT Handbook
  • Author : Enric Carreras,Carlo Dufour,Mohamad Mohty,Nicolaus Kröger
  • Publisher :Unknown
  • Release Date :2018-12-12
  • Total pages :702
  • ISBN : 9783030022785
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Summary : This Open Access edition of the European Society for Blood and Marrow Transplantation (EBMT) handbook addresses the latest developments and innovations in hematopoietic stem cell transplantation and cellular therapy. Consisting of 93 chapters, it has been written by 175 leading experts in the field. Discussing all types of stem cell and bone marrow transplantation, including haplo-identical stem cell and cord blood transplantation, it also covers the indications for transplantation, the management of early and late complications as well as the new and rapidly evolving field of cellular therapies. This book provides an unparalleled description of current practices to enhance readers’ knowledge and practice skills.

Clinical Bone Marrow and Blood Stem Cell Transplantation

Clinical Bone Marrow and Blood Stem Cell Transplantation
  • Author : Kerry Atkinson,Richard Champlin,Jerome Ritz,Willem E. Fibbe,Per Ljungman,Malcom K. Brenner
  • Publisher :Unknown
  • Release Date :2004
  • Total pages :1968
  • ISBN : 0521829127
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Summary : Drs Richard Champlin, Jerome Ritz, Willem Fibbe, Per Ljungman, and Malcom K. Brenner join Kerry Atkinson as editors of this definitive reference on the clinical practice and underlying science of hematopoietic stem cell transplantation. This third edition text is significantly revised and updated with 124 chapters balancing scientific explanations with practical information on patient care for all aspects of autologous, syngeneic, and allogeneic transplantation. This edition includes 18 new chapters on significant topics such as plasticity of stem cells, embryonic stem cells, and nonmyeloablative conditioning regimens. Thoroughly referenced through 2003, the chapters are divided into 15 sections, including biological background and practical procedures, clinical results, transplant-related and organ-specific complications, laboratory aspects, and developing areas, with a final 'breaking news' chapter from this rapidly evolving field. Over 170 internationally-recognized experts contributed to this authoritative and practical text that is an essential resource for hematologists, oncologists, and transplant specialists.

Hematopoietic Stem Cell Transplantation

Hematopoietic Stem Cell Transplantation
  • Author : Anthony D. Ho,Rainer Haas,Richard E. Champlin
  • Publisher :Unknown
  • Release Date :2000-07-25
  • Total pages :624
  • ISBN : 0824741811
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Summary : This book integrates recent advances in molecular and cell biology of hematopoietic stem cells (HSC) with developments in clinical research in stem cell-based therapy-providing an up-to-date review of novel cytokines and cellular components; animal models; cell preparation, selection, and collection; minimal residual disease and purging; expansion of progenitor cells; allogeneic and autologous transplantation; cellular gene and immunotherapy; and more. Examines key areas for treatment with HSC, including ambulatory care and monitoring, regimen-related toxicities, immunodeficiency and immunization, infection, chronic graft-versus-host and disease, secondary malignancies, and long-term quality of life. Covering stem cell pool regulation and the complex interplay of extrinsic and intrinsic events, Hematopoietic Stem Cell Transplantation summarizes current understanding and development of clinical allogeneic HSC transplantation discusses the use of allogeneic transplantations with reduced conditioning regimen or mini-transplantation considers various strategies for mobilization of HSCs from peripheral blood (PB) of normal donors details detection of bone marrow contamination by tumor cells and removal procedures focuses on efforts to increase the ex vivo transduction efficiency of human HSCs with retroviral vectors explores the effects of growth factor administration and leukapheresis on PB stem cell donors shows the impact of CD34+ cell isolation and the relevance of expansion of HSC from bone marrow for clinical use reveals how minimal residue disease detection assays are crucial for tracking the clinical significance of infused tumor cells employs automated fluorescence image cytometry to study early HSC behavior following seeding Incorporating contributions from over 90 researchers who cite more than 2180 references to encourage continued study, Hematopoietic Stem Cell Transplantation is a blue-chip reference for hematologists, hematopathologists, oncologists, cytotherapists, transplantation immunologists, and molecular biologists.

Allogeneic Stem Cell Transplantation

Allogeneic Stem Cell Transplantation
  • Author : Hillard M. Lazarus,Mary J. Laughlin
  • Publisher :Unknown
  • Release Date :2010-03-02
  • Total pages :881
  • ISBN : 1597454788
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Summary : Since the original publication of Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Allogeneic hematopoietic stem cell transplantation (HSC) has undergone several fast-paced changes. In this second edition, the editors have focused on topics relevant to evolving knowledge in the field in order to better guide clinicians in decision-making and management of their patients, as well as help lead laboratory investigators in new directions emanating from clinical observations. Some of the most respected clinicians and scientists in this discipline have responded to the recent advances in the field by providing state-of-the-art discussions addressing these topics in the second edition. The text covers the scope of human genomic variation, the methods of HLA typing and interpretation of high-resolution HLA results. Comprehensive and up-to-date, Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Second Edition offers concise advice on today's best clinical practice and will be of significant benefit to all clinicians and researchers in allogeneic HSC transplantation.

Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation

Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation
  • Author : Gerard Socie,Robert Zeiser,Bruce R. Blazar
  • Publisher :Unknown
  • Release Date :2018-09
  • Total pages :540
  • ISBN : 0128126302
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Summary : Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation, Second Edition: Models in Discovery and Translation provides clinical and scientific researchers with a deep understanding of the current research in this field and its implications for translational practice. By providing an overview of the immune biology of HSCT, an explanation of immune rejection, and detail on antigens and their role in HSCT success, this book embraces biologists and clinicians who need a broad view of the deeply complex processes involved. It then moves on to discuss the immunobiology mechanisms that influence graft-versus-host disease (GVHD), graft-versus-leukemia (GVL) effect, and transplantation success. Using illustrative figures, highlighting key issues, describing recent successes and discussing unanswered questions, this book sums up the current state of HSCT to enhance prospects for the future. New sections focus on microbiome, metabolism, micro-RNA and mRNA regulatory mechanisms and pathways in GVHD, innate lymphoid system development, recovery and function in GVHD, genetically engineered T-cell therapies and immune system engagers for GVHD and graft-vs-tumor (GVT), and hematopoietic cell transplant for tolerance induction in solid organ grafts. Brings together perspectives from leading laboratories and clinical research groups to highlight advances from bench to bedside Guides readers through the caveats that must be considered when drawing conclusions from studies with animal models Categorizes published advances in various aspects of immune biology of allogeneic HSCT to illustrate opportunities for clinical applications

Stem Cell Transplantation for Hematologic Malignancies

Stem Cell Transplantation for Hematologic Malignancies
  • Author : Robert J. Soiffer
  • Publisher :Unknown
  • Release Date :2004-01-29
  • Total pages :486
  • ISBN : 9781592597338
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Summary : A comprehensive survey of the current state-of-the-art in hematopoietic stem cell transplantation for malignant disease. The authors focus on the indications and results of transplantation for acute leukemia, chronic myelogenous leukemia, lymphoma, multiple myeloma, and breast cancer. Special attention is given to transplant-related complications, including the pathophysiology and clinical consequences of acute and chronic GVHD, delayed immune reconstitution leading to infectious complications, and organ damage to the lung and liver. Additional chapters address the sources of stem cells and the effects of graft manipulation used to eliminate residual contaminating tumor cells in autologous transplantation, or to reduce the number of T lymphocytes causing GVHD in allogenic transplantation.

Best Practices in Processing and Storage for Hematopoietic Cell Transplantation

Best Practices in Processing and Storage for Hematopoietic Cell Transplantation
  • Author : Joseph Schwartz,Beth H. Shaz
  • Publisher :Unknown
  • Release Date :2017-12-05
  • Total pages :160
  • ISBN : 9783319589497
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Summary : This concise book examines clinically relevant issues relating to the ways in which bone marrow, cord blood and apheresis products, are processed and stored for the purpose of Hematopoietic Cell Transplantation and Cell Therapy. The twin aims are to offer up-to-date content covering a wide spectrum of topics and controversies and to provide practitioners in the field of transplant and cell therapy with practical, immediately applicable information from the internationally experts in the field. Each chapter focuses on a particular subject, and numerous working tables, algorithms, and figures are included. Whenever appropriate, the reader’s attention is drawn to the availability of potentially high-impact clinical trials and expert practices. The authors are all experts who have been carefully selected for their knowledge of the topics that they address. The book will appeal to clinical and laboratory personnels, residents, fellows, and faculty members responsible for the care of hematopoietic cell transplant products and patients. Its format ensures that it will also serve as a robust, engaging tool to aid vital activities in every hematology and oncology trainee’s daily work.

Pediatric Hematopoietic Stem Cell Transplantation for Pharmacists

Pediatric Hematopoietic Stem Cell Transplantation for Pharmacists
  • Author : Carolina Witchmichen Penteado Schmidt
  • Publisher :Unknown
  • Release Date :2020-06-02
  • Total pages :123
  • ISBN : 9783030434915
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Summary : This unique book is the first on pediatric hematopoietic stem cell transplantation that is especially intended for pharmacists – in recognition of the fact that Pediatric Oncology Pharmacy is an area where more and more specific knowledge is required in daily practice, yet pharmacists who work in pediatric stem cell transplantation do not have a book addressing their specific needs. This pioneering book will likely become the new gold standard for practice, addressing subjects such as stem cells and their differentiation mechanisms; aspects of embryonic and non-embryonic stem cells; stem cell transplantation in pediatrics; stem cell sources and related technical choices; stem cell donors; scheduling transplantations; diseases and chemotherapy protocols that require stem cell transplantation; stem cell homing; engraftment and repopulation of stem cells in bone marrow; autologous stem cell transplantation in pediatrics; allogeneic stem cell transplantation in pediatrics; and indications for autologous and allogeneic pediatric stem cell transplantation. Further, it discusses pediatric graft-versus-host disease and the pharmacist; antibacterial and antifungal prophylaxis; detailed chemotherapy, conditioning and trials for pediatric stem cell transplantation; conditioning granulocyte colony-stimulating factor (G-CSF) in pediatric stem cell transplantation; analyzing prescriptions and programming a pediatric stem cell transplantation; handling chemotherapy and adjuvant drugs for pediatric stem cell transplantation; stem cell transplantation in children up to 1 year old; and clinical pharmacy in pediatric stem cell transplantation. An easy-to-read yet comprehensive guide covering a wide range of topics essential to daily practice, the book offers an invaluable asset for pediatric hemato/ oncology pharmacists, hematologist pharmacists, clinical pharmacists, pediatric pharmacists, pharmaceutical residents and researchers alike.

Best Practices of Apheresis in Hematopoietic Cell Transplantation

Best Practices of Apheresis in Hematopoietic Cell Transplantation
  • Author : Syed A. Abutalib,Anand Padmanabhan,Huy P. Pham,Nina Worel
  • Publisher :Unknown
  • Release Date :2019-12-09
  • Total pages :211
  • ISBN : 3319551302
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Summary : In this book, world-renowned experts in the field of hematopoietic cell transplantation examine a range of issues and controversies relating to apheresis, with the aim of identifying current trends and best practices. Readers will find up-to-date guidance on donor evaluation, CD34+ cell mobilization strategies, options and selection of apheresis device, anticoagulation techniques in apheresis, the role of prediction algorithms in determining procedure eligibility and length, and the prevention and management of complications. Applications of apheresis devices in the processing of bone marrow grafts are discussed, and detailed attention is devoted to the indications and rationale for therapeutic apheresis procedures, with individual chapters focusing on therapeutic plasma exchange and immunoadsorption, red cell exchange, and extracorporeal photopheresis. Finally, the applications of apheresis in pediatric donors and in resource-limiting environments are considered. This book, featuring numerous helpful tables, algorithms, and figures, will be of high practical value for residents, fellows, faculty members and other healthcare personnel involved in hematopoietic cell transplantation.

Pluripotent Stem Cells

Pluripotent Stem Cells
  • Author : Minoru Tomizawa
  • Publisher :Unknown
  • Release Date :2016-07-20
  • Total pages :532
  • ISBN : 9789535124719
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Summary : Pluripotent stem cells have distinct characteristics: self-renewal and the potential to differentiate into various somatic cells. In recent years, substantial advances have been made from basic science to clinical applications. The vast amount knowledge available makes obtaining concise yet sufficient information difficult, hence the purpose of this book. In this book, embryonic stem cells, induced pluripotent stem cells, and mesenchymal stem cells are discussed. The book is divided into five sections: pluripotency, culture methods, toxicology, disease models, and regenerative medicine. The topics covered range from new concepts to current technologies. Readers are expected to gain useful information from expert contributors.

Sickle Cell Disease and Hematopoietic Stem Cell Transplantation

Sickle Cell Disease and Hematopoietic Stem Cell Transplantation
  • Author : Emily Riehm Meier,Allistair Abraham,Ross M. Fasano
  • Publisher :Unknown
  • Release Date :2017-09-19
  • Total pages :334
  • ISBN : 9783319623283
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Summary : This book provides a comprehensive, state-of-the art review of hematopoietic stem cell transplantation (HSCT) for sickle cell disease (SCD). The book reviews new data about risk prediction for severe SCD, outlines the unique challenges of HSCT for patients with SCD, profiles the supportive care guidelines for patients who are undergoing HSCT, highlights our current understanding of the best transfusion support for SCD patients prior to, during and after HSCT, and provides new perspectives about the ethics of HSCT for pediatric patients with SCD. Published in the last few years, several landmark phase III trials that utilize matched unrelated and haploidentical donors for HSCT in SCD patients are also placed in context with respect to current management. Written by experts in the field, Sickle Cell Disease and Hematopoietic Stem Cell Transplantation is a valuable resource for physicians and researchers dealing with and interested in this challenging, yet exciting, curative therapy for sickle cell disease, that will help guide patient management and stimulate investigative efforts.

Establishing a Hematopoietic Stem Cell Transplantation Unit

Establishing a Hematopoietic Stem Cell Transplantation Unit
  • Author : Éliane Gluckman,Dietger Niederwieser,Mahmoud Aljurf
  • Publisher :Unknown
  • Release Date :2017-11-17
  • Total pages :306
  • ISBN : 9783319593586
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Summary : This text aims to provide simplified practical guidelines to start a hematopoietic stem cell transplantation unit which could be implemented in most centers and countries worldwide. The book also provides guidelines for existing transplantation units to upgrade their practice and implement new policies and procedures, in addition to developing therapies according to latest international standards and regulations. The book covers a wide range of practical implementation tools including HSCT program team structure, building inpatient and outpatient HSCT units, requisite laboratory support for transplantation program, practical aspects of stem cell collection and processing, HSCT program quality management, education and training, and data management. The book also addresses cost effectiveness and recommendations for establishing transplantation program in countries with limited resources. Written by group of internationally established experts in their corresponding hematopoietic stem cell transplantation fields, with contributions from many leaders of hematopoietic stem cell transplantation organizations, Establishing a Hematopoietic Stem Cell Transplantation Unit: A Practical Guide is an essential, practical resource for all members of the multidisciplinary hematopoietic stem cell transplantation team.

Stem Cells and Their Potential for Clinical Application

Stem Cells and Their Potential for Clinical Application
  • Author : Nadja M. Bilko,Boris Fehse,Wolfram Ostertag,Carol Stocking,Axel R. Zander
  • Publisher :Unknown
  • Release Date :2008
  • Total pages :274
  • ISBN : 9781402064678
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Summary : Proceedings of the NATO Advanced Research Workshop on Stem Cells and their Potential for Clinical Application, Kiev and Simeiz, Ukraine, August 23–31, 2006

Thomas' Hematopoietic Cell Transplantation

Thomas' Hematopoietic Cell Transplantation
  • Author : Frederick R. Appelbaum,Stephen J. Forman,Robert S. Negrin,Karl G. Blume
  • Publisher :Unknown
  • Release Date :2011-09-26
  • Total pages :1752
  • ISBN : 9781444357455
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Summary : This outstanding reference source on bone marrow transplantation has become recognised as the bible in the field. This fourth edition has been fully revised to reflect latest developments, and now features over 500 illustrations, including a colour plate section. The need for this new edition cannot be overstated - more than 13,000 new cases per year of haematopoietic stem cell transplantation have been reported to the International Bone Marrow Transplant Registry The original editor, Donnall Thomas, was a pioneer in stem cell research and won the 1990 Nobel Prize for his discoveries concerning organ and cell transplantation in the treatment of human diseases. The book also now includes a fully searchable CD with PDFs of the entire content.

Hematopoietic Stem Cell Transplantation

Hematopoietic Stem Cell Transplantation
  • Author : John R. Wingard
  • Publisher :Unknown
  • Release Date :2010
  • Total pages :729
  • ISBN : 380559576X
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Summary :