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Human Embryos and Preimplantation Genetic Technologies

Human Embryos and Preimplantation Genetic Technologies
  • Author : E. Scott Sills,Gianpiero D. Palermo
  • Publisher :Unknown
  • Release Date :2019-05-01
  • Total pages :222
  • ISBN : 9780128167441
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Summary : Human Embryos and Preimplantation Genetic Technologies: Ethical, Social, and Public Policy Aspects presents the first holistic analysis of PGD and PGS as it is practiced and regulated worldwide. In addition to scientific and technical aspects, the book provides perspectives on the ethical, legal, religious, policy and social implications of global assisted reproduction technologies, including in Africa, Asia, Europe, North and South America, and Australia. Chapters cover history, ethics, feminism, family dynamics, psychological and interpersonal factors, the current state of PGD and PGS in 20 different sovereign nations and religious communities, and provide an analysis of public policy concerns and future directions. Provides an in-depth discussion of PGD and PGS as practiced and regulated worldwide Offers an accessible resource for researchers, medical professionals, patients, regulators and policymakers seeking expert opinions on PGS and PGD Contains chapters contributed by international clinicians, researchers and thought leaders in the field of assisted reproductive technology

Handbook of New Genetic Diagnostic Technologies in Reproductive Medicine

Handbook of New Genetic Diagnostic Technologies in Reproductive Medicine
  • Author : Carlos Simón,Carmen Rubio
  • Publisher :Unknown
  • Release Date :2017-12-14
  • Total pages :179
  • ISBN : 9781498763318
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Summary : Different genetic diagnostic and treatment options are used worldwide to improve routine IVF procedures for the benefit of patients. This handbook updates the new genetic diagnostic technologies that have been translated to practice aiming to improve outcomes in the clinic and have a healthy baby at home. Chapters cover the use of genetic technologies in a personalized manner to unravel the possible genetic risks for the couple wishing to conceive, in terms of sperm, the embryo, the endometrium, miscarriage, and finally the fetus.

Human Preimplantation Embryo Selection

Human Preimplantation Embryo Selection
  • Author : Jacques Cohen,Kay Elder
  • Publisher :Unknown
  • Release Date :2007-09-26
  • Total pages :384
  • ISBN : 0203089715
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Summary : The most profound dilemma in assisted reproduction to date is the inability to recognize potentially viable embryos before their replacement into the reproductive tract. Application of increasingly advanced new technology has allowed the field of embryo evaluation to evolve rapidly and dramatically over the past five years. Human Preimplantation Embryo Selection assembles the leaders in the field of assisted reproduction to discuss their visions of dealing with the topic of embryo selection in the light of the limitations involving the fragility of the early human embryo. The purpose of this book is to shed light on the ever-expanding techniques that are being employed and evaluated with regard to embryo selection. A comprehensive overview may guide the ART practitioner in choice of techniques and evaluation of benefits and drawbacks. This book will provide an up-to-date overview and reference source: an invaluable tool for assisted reproductive practice worldwide.

Human Genome Editing

Human Genome Editing
  • Author : National Academies of Sciences, Engineering, and Medicine,National Academy of Medicine,National Academy of Sciences,Committee on Human Gene Editing: Scientific, Medical, and Ethical Considerations
  • Publisher :Unknown
  • Release Date :2017-08-13
  • Total pages :328
  • ISBN : 9780309452885
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Summary : Genome editing is a powerful new tool for making precise alterations to an organism's genetic material. Recent scientific advances have made genome editing more efficient, precise, and flexible than ever before. These advances have spurred an explosion of interest from around the globe in the possible ways in which genome editing can improve human health. The speed at which these technologies are being developed and applied has led many policymakers and stakeholders to express concern about whether appropriate systems are in place to govern these technologies and how and when the public should be engaged in these decisions. Human Genome Editing considers important questions about the human application of genome editing including: balancing potential benefits with unintended risks, governing the use of genome editing, incorporating societal values into clinical applications and policy decisions, and respecting the inevitable differences across nations and cultures that will shape how and whether to use these new technologies. This report proposes criteria for heritable germline editing, provides conclusions on the crucial need for public education and engagement, and presents 7 general principles for the governance of human genome editing.

Preimplantation Genetic Diagnosis in Clinical Practice

Preimplantation Genetic Diagnosis in Clinical Practice
  • Author : Tarek El-Toukhy,Peter Braude
  • Publisher :Unknown
  • Release Date :2013-11-08
  • Total pages :228
  • ISBN : 9781447129486
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Summary : Preimplantation genetic diagnosis (PGD) is a rapidly advancing field of reproductive genetics. With the significant improvements achieved over the last few years in the understanding of many genetic diseases and in the techniques of molecular genetic testing, new genetic diseases are being added to the list of conditions amenable to PGD almost on a weekly basis. Therefore, the subject of PGD is becoming relevant to a much wider variety of medical disciplines and an increasing number of patients who may wish to know more about this treatment option. This unique book offers a comprehensive yet practical “user-friendly” guide to preimplantation genetic diagnosis (PGD). It provides understanding of and insight into the complete procedure, its recent clinical and laboratory developments and its future prospects, whilst offering an easy point of reference for patient enquiries. Concluding with perspectives on the ethical and social issues often encountered by healthcare professionals counselling patients with regards to PGD. Each chapter within Preimplantation Genetic Diagnosis in Clinical Practice is written by established authorities in their fields. An essential resource for PGD specialists and non-specialists, and for all practitioners working within the disciplines of fertility, reproductive medicine and medical genetics.

Human Reproductive Genetics

Human Reproductive Genetics
  • Author : Juan A. Garcia-Velasco,Emre Seli
  • Publisher :Unknown
  • Release Date :2020-04-19
  • Total pages :340
  • ISBN : 9780128167496
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Summary : Human Reproductive Genetics: Emerging Technologies and Clinical Applications presents a great reference for clinicians and researchers in reproductive medicine. Part I includes a brief background of genetics and epigenetics, probability of disease, and the different techniques that are being used today for analysis and genetic counseling. Part II focuses on the analysis of the embryo, current controversies and future concepts. Part III comprises different clinical scenarios that clinicians frequently face in practice. The increasing amount of genetic tests available and the growing information that patients handle makes this section a relevant part of the fertility treatment discussion. Finally, Part IV concludes with the psychological aspects of genetic counseling and the role of counselor and bioethics in human reproduction. Provides an essential reference for clinicians involved in reproductive medicine Builds foundational knowledge on new genetic tests coming into the clinical scenario for physicians involved with patients Assembles critically evaluated chapters that cover basic concepts of genetics and epigenetics and the techniques involved, including preimplantation genetic testing, controversies, and more

Textbook of Human Reproductive Genetics

Textbook of Human Reproductive Genetics
  • Author : Karen Sermon,Stéphane Viville
  • Publisher :Unknown
  • Release Date :2014-04-10
  • Total pages :200
  • ISBN : 9781107683587
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Summary : This book brings together genetics, reproductive biology and medicine for an integrative view of the emerging specialism of reproductive genetics.

Human Germline Modification and the Right to Science

Human Germline Modification and the Right to Science
  • Author : Andrea Boggio,Cesare P. R. Romano,Jessica Almqvist
  • Publisher :Unknown
  • Release Date :2020-01-09
  • Total pages :324
  • ISBN : 9781108499873
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Summary : A survey of the regulation of human germline genome modification in eighteen countries and the emerging international standards.

The End of Sex and the Future of Human Reproduction

The End of Sex and the Future of Human Reproduction
  • Author : Henry T. Greely
  • Publisher :Unknown
  • Release Date :2016-05-30
  • Total pages :381
  • ISBN : 9780674728967
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Summary : Within twenty, maybe forty, years most people in developed countries will stop having sex for the purpose of reproduction. Instead, prospective parents will be told as much as they wish to know about the genetic makeup of dozens of embryos, and they will pick one or two for implantation, gestation, and birth. And it will be safe, lawful, and free. In this work of prophetic scholarship, Henry T. Greely explains the revolutionary biological technologies that make this future a seeming inevitability and sets out the deep ethical and legal challenges humanity faces as a result. “Readers looking for a more in-depth analysis of human genome modifications and reproductive technologies and their legal and ethical implications should strongly consider picking up Greely’s The End of Sex and the Future of Human Reproduction...[It has] the potential to empower readers to make informed decisions about the implementation of advancements in genetics technologies.” —Dov Greenbaum, Science “[Greely] provides an extraordinarily sophisticated analysis of the practical, political, legal, and ethical implications of the new world of human reproduction. His book is a model of highly informed, rigorous, thought-provoking speculation about an immensely important topic.” —Glenn C. Altschuler, Psychology Today

Engineering the Human Germline

Engineering the Human Germline
  • Author : Gregory Stock,John Howland Campbell
  • Publisher :Unknown
  • Release Date :2000
  • Total pages :169
  • ISBN : 9780195133028
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Summary : This book explores the many prospects, challenges and ethical questions that surround the engineering of our reproductive cells. It is an accessible, three-part examination, moving from focused, realistic assessments of the promise and problems for this advancing technology to a section of short essays on the implications of our technological ability. Also included is a panel discussion in which leading scientists, ethicists, and public policy workers give voice to their thoughts and concerns regarding our impending genetic technologies. Many world leaders in these fields, including Leroy Hood, French Anderson, Mario Capecchi, Daniel Koshland, Michael Rose, Lee Silver, and James Watson, have contributed to this volume, providing the essential elements of the debate over germline engineering. If you have ever pondered the question: "Would I be willing to genetically alter my own child-to-be, given a safe, reliable technology, offering a tempting possibility?", this book will be an indispensable guide.

From Chance to Choice

From Chance to Choice
  • Author : Allen Buchanan,Dan W. Brock,Norman Daniels,Daniel Wikler
  • Publisher :Unknown
  • Release Date :2001-11-12
  • Total pages :229
  • ISBN : 9781316583937
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Summary : This book, written by four internationally renowned bioethicists and first published in 2000, was the first systematic treatment of the fundamental ethical issues underlying the application of genetic technologies to human beings. Probing the implications of the remarkable advances in genetics, the authors ask how should these affect our understanding of distributive justice, equality of opportunity, the rights and obligations as parents, the meaning of disability, and the role of the concept of human nature in ethical theory and practice. The book offers a historical context to contemporary debate over the use of these technologies by examining the eugenics movement of the late nineteenth and early twentieth centuries. The questions raised in this book will be of interest to any reflective reader concerned about science and society and the rapid development of biotechnology, as well as to professionals in such areas as philosophy, bioethics, medical ethics, health management, law, and political science.

Reproduction and Responsibility, The Regulation of New Biotechnologies, March 2004

Reproduction and Responsibility, The Regulation of New Biotechnologies, March 2004
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2004
  • Total pages :229
  • ISBN : MINN:31951D024617321
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Summary :

Reproduction and Responsibility

Reproduction and Responsibility
  • Author : President's Council on Bioethics (U.S.)
  • Publisher :Unknown
  • Release Date :2004
  • Total pages :252
  • ISBN : NYPL:33433083674790
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Reproductive Genetics

Reproductive Genetics
  • Author : Sean Kehoe,Lyn Chitty,Tessa Homfray
  • Publisher :Unknown
  • Release Date :2009-11
  • Total pages :242
  • ISBN : 9781906985165
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Summary : This book presents the findings of the RCOG Study Group findings on genetics underlying reproductive function.

Science and Babies

Science and Babies
  • Author : Institute of Medicine,Suzanne Wymelenberg
  • Publisher :Unknown
  • Release Date :1990-02-01
  • Total pages :184
  • ISBN : 9780309041362
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Summary : By all indicators, the reproductive health of Americans has been deteriorating since 1980. Our nation is troubled by rates of teen pregnancies and newborn deaths that are worse than almost all others in the Western world. Science and Babies is a straightforward presentation of the major reproductive issues we face that suggests answers for the public. The book discusses how the clash of opinions on sex and family planning prevents us from making a national commitment to reproductive health; why people in the United States have fewer contraceptive choices than those in many other countries; what we need to do to improve social and medical services for teens and people living in poverty; how couples should "shop" for a fertility service and make consumer-wise decisions; and what we can expect in the future--featuring interesting accounts of potential scientific advances.

Genetic Disorders and the Fetus

Genetic Disorders and the Fetus
  • Author : Aubrey Milunsky
  • Publisher :Unknown
  • Release Date :2012-12-06
  • Total pages :704
  • ISBN : 9781468434385
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Summary : Technological advances continue to expand the number of genetic disorders that can be diagnosed in utero. Utilization of this new technology has de manded special expertise available in relatively few academic centers. As these new applications have become more widespread so have the realities of the medicolegal implications. Notwithstanding the laboratory challenges, most legal action, at least in the United States, has arisen from the physician's failure to inform a patient about the risks of a genetic disorder or the oppor tunities presented by prenatal diagnosis. Hence an extensive thorough reex amination of the subject seems appropriate and timely. The steady escalation in the number of prenatal genetic studies now being done in the western world makes it imperative for the physician to have a thorough comprehension of the subject in its entirety. I am, therefore, fortu nate in having colleagues who as acknowledged experts have shared their knowledge and experience in order to make this volume a major critical repository of facts and guidance about prenatal genetic diagnosis. The subject matter ranges from a consideration of required genetic counseling through the intricacies of establishing prenatal diagnoses. Special attention is focused on new advances using ultrasound, a-fetoprotein, fetoscopy, and first trimester diagnosis. Both ethical and legal implications are discussed in detail, as is the development of public policy.

Human Gametes and Preimplantation Embryos

Human Gametes and Preimplantation Embryos
  • Author : David K. Gardner,Denny Sakkas,Emre Seli,Dagan Wells
  • Publisher :Unknown
  • Release Date :2013-05-27
  • Total pages :306
  • ISBN : 9781461466512
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Summary : In recent years, the advancing science and increasing availability of assisted reproduction have given new hope to infertile couples. However, the use of IVF and ART has also led to marked increases in the number of multiple-infant live births. This poses a public health concern, as these neonates have a higher rate of pre-term delivery, compromising their survival chances and increasing their risk of lifelong disability. By optimizing the selection of gametes and embryos with high probabilities of implantation, it is possible to reduce the number of embryos transferred and, by extension, the number of high-risk multiple gestations, while maintaining or increasing pregnancy rates. Human Gametes and Preimplantation Embryos: Assessment and Diagnosis provides a broad yet concise overview of established and developing methodologies for assessment of gamete and embryo viability in assisted reproduction. This book elucidates the best practices for precisely selecting viable specimens based on morphology and cleavage rate and covers the spectrum of emerging adjunctive technologies for predicting reproductive potential. The authors present their extensive knowledge of “omics” approaches (genomics, transcriptomics, proteomics, and metabolomics), with unbiased delineation of the associated advantages and potential pitfalls. This valuable clinical resource is well suited to infertility specialists, Ob/Gyn physicians, IVF laboratory technicians, and researchers in the fields of embryology and reproductive medicine.

Born and Made

Born and Made
  • Author : Sarah Franklin,Celia Roberts
  • Publisher :Unknown
  • Release Date :2006-10-30
  • Total pages :288
  • ISBN : 9781400835423
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Summary : Are new reproductive and genetic technologies racing ahead of a society that is unable to establish limits to their use? Have the "new genetics" outpaced our ability to control their future applications? This book examines the case of preimplantation genetic diagnosis (PGD), the procedure used to prevent serious genetic disease by embryo selection, and the so-called "designer baby" method. Using detailed empirical evidence, the authors show that far from being a runaway technology, the regulation of PGD over the past fifteen years provides an example of precaution and restraint, as well as continual adaptation to changing social circumstances. Through interviews, media and policy analysis, and participant observation at two PGD centers in the United Kingdom, Born and Made provides an in-depth sociological examination of the competing moral obligations that define the experience of PGD. Among the many novel findings of this pathbreaking ethnography of reproductive biomedicine is the prominence of uncertainty and ambivalence among PGD patients and professionals--a finding characteristic of the emerging "biosociety," in which scientific progress is inherently paradoxical and contradictory. In contrast to much of the speculative futurology that defines this field, Born and Made provides a timely and revealing case study of the on-the-ground decision-making that shapes technological assistance to human heredity.

Human Cloning and Embryonic Stem Cell Research After Seoul

Human Cloning and Embryonic Stem Cell Research After Seoul
  • Author : United States. Congress. House. Committee on Government Reform. Subcommittee on Criminal Justice, Drug Policy, and Human Resources
  • Publisher :Unknown
  • Release Date :2006
  • Total pages :245
  • ISBN : PURD:32754075476485
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Summary :

Genetic Diversity and Disease Susceptibility

Genetic Diversity and Disease Susceptibility
  • Author : Yamin Liu
  • Publisher :Unknown
  • Release Date :2018-10-17
  • Total pages :164
  • ISBN : 9781789842012
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Summary : Polymorphism or variation in DNA sequence can affect individual phenotypes such as color of skin or eyes, susceptibility to diseases, and response to drugs, vaccines, chemicals, and pathogens. Especially, the interfaces between genetics, disease susceptibility, and pharmacogenomics have recently been the subject of intense research activity. This book is a self-contained collection of valuable scholarly papers related to genetic diversity and disease susceptibility, pharmacogenomics, ongoing advances in technology, and analytic methods in this field. The book contains nine chapters that cover the three main topics of genetic polymorphism, genetic diversity, and disease susceptibility and pharmacogenomics. Hence, this book is particularly useful to academics, scientists, physicians, pharmacists, practicing researchers, and postgraduate students whose work relates to genetic polymorphisms.

Shaping Genes; Ethics, Law and Science of Using Genetic Technology in Medicine and Agriculture

Shaping Genes; Ethics, Law and Science of Using Genetic Technology in Medicine and Agriculture
  • Author : Macer, D. R. J.
  • Publisher :Unknown
  • Release Date :1990
  • Total pages :421
  • ISBN : CORNELL:31924067841969
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Summary :