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Textbook of Human Reproductive Genetics

Textbook of Human Reproductive Genetics
  • Author : Karen Sermon,Stéphane Viville
  • Publisher :Unknown
  • Release Date :2014-04-10
  • Total pages :200
  • ISBN : 9781107683587
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Summary : This book brings together genetics, reproductive biology and medicine for an integrative view of the emerging specialism of reproductive genetics.

Human Reproductive Genetics

Human Reproductive Genetics
  • Author : Juan A. Garcia-Velasco,Emre Seli
  • Publisher :Unknown
  • Release Date :2020-04-19
  • Total pages :340
  • ISBN : 9780128167496
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Summary : Human Reproductive Genetics: Emerging Technologies and Clinical Applications presents a great reference for clinicians and researchers in reproductive medicine. Part I includes a brief background of genetics and epigenetics, probability of disease, and the different techniques that are being used today for analysis and genetic counseling. Part II focuses on the analysis of the embryo, current controversies and future concepts. Part III comprises different clinical scenarios that clinicians frequently face in practice. The increasing amount of genetic tests available and the growing information that patients handle makes this section a relevant part of the fertility treatment discussion. Finally, Part IV concludes with the psychological aspects of genetic counseling and the role of counselor and bioethics in human reproduction. Provides an essential reference for clinicians involved in reproductive medicine Builds foundational knowledge on new genetic tests coming into the clinical scenario for physicians involved with patients Assembles critically evaluated chapters that cover basic concepts of genetics and epigenetics and the techniques involved, including preimplantation genetic testing, controversies, and more

Human Reproductive and Prenatal Genetics

Human Reproductive and Prenatal Genetics
  • Author : Peter C. K. Leung,Jie Qiao
  • Publisher :Unknown
  • Release Date :2018-08-28
  • Total pages :709
  • ISBN : 9780128135716
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Summary : Human Reproductive and Prenatal Genetics presents the latest material from a detailed molecular, cellular and translational perspective. Considering its timeliness and potential international impact, this all-inclusive and authoritative work is ideal for researchers, students, and clinicians worldwide. Currently, there are no comprehensive books covering the field of human reproductive and prenatal genetics. As such, this book aims to be among the largest and most useful references available. Features chapter contributions from leading international scientists and clinicians Provides in-depth coverage of key topics in human reproductive and prenatal genetics, including genetic controls, fertilization and implantation, in vitro culture of the human embryo for the study of post-implantation development, and more Identifies how researchers and clinicians can implement the latest genetic, epigenetic, and –omics based approaches

Reproductive Genetics

Reproductive Genetics
  • Author : Sean Kehoe,Lyn Chitty,Tessa Homfray
  • Publisher :Unknown
  • Release Date :2009-11
  • Total pages :242
  • ISBN : 9781906985165
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Summary : This book presents the findings of the RCOG Study Group findings on genetics underlying reproductive function.

The Ethics of Reproductive Genetics

The Ethics of Reproductive Genetics
  • Author : Marta Soniewicka
  • Publisher :Unknown
  • Release Date :2018-04-24
  • Total pages :257
  • ISBN : 9783319606842
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Summary : This book is aimed at analyzing the foundations of medical ethics by considering different moral theories and their implications for judgments in clinical practice and policy-making. It provides a review of the major types of ethical theory that can be applied to medical and bioethical issues concerning reproductive genetics. In response to the debate on the most adequate ethical doctrine to guide biomedical decisions, this book formulates views that capture the best elements in each, bearing in mind their differences and taking into account the specific character of medicine. No historically influential position in ethics is by itself adequate to be applied to reproductive decisions. Thus, this book attempts to offer a pluralistic approach to biomedical research and medical practice. One usually claims that there are some basic principles (non-maleficence, beneficence, confidentiality, autonomy, and justice) which constitute the foundations of bioethics and medical ethics. Yet these principles conflict with each other and one needs some criteria to solve these conflicts and to specify the scope of application of these principles. Exploring miscellaneous ethical approaches as introduced to biomedicine, particularly to reproductive genetics, the book shall elucidate their different assumptions concerning human nature and the relations between healthcare providers, recipients, and other affected parties (e.g. progeny, relatives, other patients, society). The book attempts to answer the question of whether the tension between these ethical doctrines generates conflict in the field of biomedicine or if these competing approaches could in some way complement each other. In this respect, lecturers and researchers in bioethics would be interested in this reading this book.

Reproductomics

Reproductomics
  • Author : José A. Horcajadas,Jaime Gosálvez
  • Publisher :Unknown
  • Release Date :2018-07-23
  • Total pages :425
  • ISBN : 9780128126769
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Summary : Recent advances in genomic and omics analysis have triggered a revolution affecting nearly every field of medicine, including reproductive medicine, obstetrics, gynecology, andrology, and infertility treatment. Reproductomics: The –Omics Revolution and Its Impact on Human Reproductive Medicine demonstrates how various omics technologies are already aiding fertility specialists and clinicians in characterizing patients, counseling couples towards pregnancy success, informing embryo selection, and supporting many other positive outcomes. A diverse range of chapters from international experts examine the complex relationship between genomics, transcriptomics, proteomics, and metabolomics and their role in human reproduction, identifying molecular factors of clinical significance. With this book Editors Jaime Gosálvez and José A. Horcajadas have provided researchers and clinicians with a strong foundation for a new era of personalized reproductive medicine. Thoroughly discusses how genomics and other omics approaches aid clinicians in various areas of reproductive medicine Identifies specific genomic and molecular factors of translational value in treating infertility and analyzing patient data Features chapter contributions by leading international experts

The End of Sex and the Future of Human Reproduction

The End of Sex and the Future of Human Reproduction
  • Author : Henry T. Greely
  • Publisher :Unknown
  • Release Date :2016-05-30
  • Total pages :381
  • ISBN : 9780674728967
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Summary : Within twenty, maybe forty, years most people in developed countries will stop having sex for the purpose of reproduction. Instead, prospective parents will be told as much as they wish to know about the genetic makeup of dozens of embryos, and they will pick one or two for implantation, gestation, and birth. And it will be safe, lawful, and free. In this work of prophetic scholarship, Henry T. Greely explains the revolutionary biological technologies that make this future a seeming inevitability and sets out the deep ethical and legal challenges humanity faces as a result. “Readers looking for a more in-depth analysis of human genome modifications and reproductive technologies and their legal and ethical implications should strongly consider picking up Greely’s The End of Sex and the Future of Human Reproduction...[It has] the potential to empower readers to make informed decisions about the implementation of advancements in genetics technologies.” —Dov Greenbaum, Science “[Greely] provides an extraordinarily sophisticated analysis of the practical, political, legal, and ethical implications of the new world of human reproduction. His book is a model of highly informed, rigorous, thought-provoking speculation about an immensely important topic.” —Glenn C. Altschuler, Psychology Today

Genetics of Human Infertility

Genetics of Human Infertility
  • Author : P.H. Vogt
  • Publisher :Unknown
  • Release Date :2017-09-12
  • Total pages :178
  • ISBN : 9783318060980
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Summary : Infertility affects more than one in ten couples worldwide and is related to highly heterogeneous pathologies sometimes only discernible in the germ line. Its complex etiology often, but not always, includes genetic factors besides anatomical defects, immunological interference, and environmental aspects. Nearly 30% of infertility cases are probably caused only by genetic defects. Thereby experimental animal knockout models convincingly show that infertility can be caused by single or multiple gene defects. Translating those basic research findings into clinical studies is challenging, leaving genetic causes for the vast majority of infertility patients unexplained. Nevertheless, a large number of candidate genes have been revealed by sophisticated molecular methods. This book provides a comprehensive overview on the subject of infertility written by the leading authorities in this field. It covers topics including basic biological, cytological, and molecular studies, as well as common and uncommon syndromes. It is a must-read for human geneticists, endocrinologists, epidemiologists, zoologists, and counsellors in human genetics, infertility, and assisted reproduction.

Clinical Ethics at the Crossroads of Genetic and Reproductive Technologies

Clinical Ethics at the Crossroads of Genetic and Reproductive Technologies
  • Author : Sorin Hostiuc
  • Publisher :Unknown
  • Release Date :2018-08-07
  • Total pages :431
  • ISBN : 9780128137659
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Summary : Clinical Ethics at the Crossroads of Genetic and Reproductive Technologies offers thorough discussions on preconception carrier screening, genetic engineering and the use of CRISPR gene editing, mitochondrial gene replacement therapy, sex selection, predictive testing, secondary findings, embryo reduction and the moral status of the embryo, genetic enhancement, and the sharing of genetic data. Chapter contributions from leading bioethicists and clinicians encourage a global, holistic perspective on applied challenges and the moral questions relating the implementation of genetic reproductive technology. The book is an ideal resource for practitioners, regulators, lawmakers, clinical researchers, genetic counselors and graduate and medical students. As the Human Genome Project has triggered a technological revolution that has influenced nearly every field of medicine, including reproductive medicine, obstetrics, gynecology, andrology, prenatal genetic testing, and gene therapy, this book presents a timely resource. Provides practical analysis of the ethical issues raised by cutting-edge techniques and recent advances in prenatal and reproductive genetics Contains contributions from leading bioethicists and clinicians who offer a global, holistic perspective on applied challenges and moral questions relating to genetic and genomic reproductive technology Discusses preconception carrier screening, genetic engineering and the use of CRISPR gene editing, mitochondrial gene replacement therapy, ethical issues, and more

Handbook of New Genetic Diagnostic Technologies in Reproductive Medicine

Handbook of New Genetic Diagnostic Technologies in Reproductive Medicine
  • Author : Carlos Simón,Carmen Rubio
  • Publisher :Unknown
  • Release Date :2017-12-14
  • Total pages :179
  • ISBN : 9781498763318
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Summary : Different genetic diagnostic and treatment options are used worldwide to improve routine IVF procedures for the benefit of patients. This handbook updates the new genetic diagnostic technologies that have been translated to practice aiming to improve outcomes in the clinic and have a healthy baby at home. Chapters cover the use of genetic technologies in a personalized manner to unravel the possible genetic risks for the couple wishing to conceive, in terms of sperm, the embryo, the endometrium, miscarriage, and finally the fetus.

Human Embryos and Preimplantation Genetic Technologies

Human Embryos and Preimplantation Genetic Technologies
  • Author : E. Scott Sills,Gianpiero D. Palermo
  • Publisher :Unknown
  • Release Date :2019-05-01
  • Total pages :222
  • ISBN : 9780128167441
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Summary : Human Embryos and Preimplantation Genetic Technologies: Ethical, Social, and Public Policy Aspects presents the first holistic analysis of PGD and PGS as it is practiced and regulated worldwide. In addition to scientific and technical aspects, the book provides perspectives on the ethical, legal, religious, policy and social implications of global assisted reproduction technologies, including in Africa, Asia, Europe, North and South America, and Australia. Chapters cover history, ethics, feminism, family dynamics, psychological and interpersonal factors, the current state of PGD and PGS in 20 different sovereign nations and religious communities, and provide an analysis of public policy concerns and future directions. Provides an in-depth discussion of PGD and PGS as practiced and regulated worldwide Offers an accessible resource for researchers, medical professionals, patients, regulators and policymakers seeking expert opinions on PGS and PGD Contains chapters contributed by international clinicians, researchers and thought leaders in the field of assisted reproductive technology

Human Reproductive Biology

Human Reproductive Biology
  • Author : Richard E. Jones,Kristin H. Lopez
  • Publisher :Unknown
  • Release Date :2006-05-15
  • Total pages :624
  • ISBN : 0080508367
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Summary : This acclaimed text has been fully revised and updated, now incorporating issues including aging of the reproductive system, and updates on the chapters on conception and Gamete Transport and Fertilization, and Pregnancy. Human Reproductive Biology, Third Edition emphasizes the biological and biomedical aspects of human reproduction, explains advances in reproductive science and discusses the choices and concerns of today. Generously illustrated in full color, the text provides current information about human reproductive anatomy and physiology. The ideal book for courses on human reproductive biology - includes chapter introductions, sidebars on related topics of interest, chapter summaries and suggestions for further reading. All material competely updated with the latest research results, methods, and topics now organized to facilitate logical presentation of topics New chapters on Reproductive Senescence, Conception: Gamete Transport, Fertilization, Pregnancy: Maternal Aspects and Pregnancy: Fetal Development Full color illustrations

11th World Congress on In Vitro Fertilization and Human Reproductive Genetics

11th World Congress on In Vitro Fertilization and Human Reproductive Genetics
  • Author : Masayoshi Okada
  • Publisher :Unknown
  • Release Date :1999
  • Total pages :420
  • ISBN : CHI:55546897
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Summary :

Scientific and Medical Aspects of Human Reproductive Cloning

Scientific and Medical Aspects of Human Reproductive Cloning
  • Author : National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Policy and Global Affairs,Committee on Science, Engineering, and Public Policy
  • Publisher :Unknown
  • Release Date :2002-06-17
  • Total pages :294
  • ISBN : 9780309076371
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Summary : Human reproductive cloning is an assisted reproductive technology that would be carried out with the goal of creating a newborn genetically identical to another human being. It is currently the subject of much debate around the world, involving a variety of ethical, religious, societal, scientific, and medical issues. Scientific and Medical Aspects of Human Reproductive Cloning considers the scientific and medical sides of this issue, plus ethical issues that pertain to human-subjects research. Based on experience with reproductive cloning in animals, the report concludes that human reproductive cloning would be dangerous for the woman, fetus, and newborn, and is likely to fail. The study panel did not address the issue of whether human reproductive cloning, even if it were found to be medically safe, would beâ€"or would not beâ€"acceptable to individuals or society.

11th World Congress on In Vitro Fertilisation and Human Reproductive Genetics, 9-14th May 1999 Sydney, Australia

11th World Congress on In Vitro Fertilisation and Human Reproductive Genetics, 9-14th May 1999 Sydney, Australia
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :1999
  • Total pages :319
  • ISBN : OCLC:223758755
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Summary :

Paternal Influences on Human Reproductive Success

Paternal Influences on Human Reproductive Success
  • Author : Douglas T. Carrell
  • Publisher :Unknown
  • Release Date :2013-04-11
  • Total pages :229
  • ISBN : 9781107355071
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Summary : Historically, sperm have been seen as simply a mechanism of transferring a haploid set of chromosomes to the oocyte. However, data from assisted reproduction therapies (ART) have demonstrated that in many couples the sperm appears to be responsible for abnormal embryogenesis. Recent advances in genetic and epigenetic techniques have identified key mechanisms by which the sperm, and the DNA carried by the sperm, can affect early embryonic development. Paternal Influences on Human Reproductive Success examines the genetic and epigenetic influences on embryogenesis, as well as practical clinical factors related to the male contribution to reproductive success. It also provides 'cutting edge' data and analysis of recent evaluations of the role of advanced paternal age, environmental influences and lifestyle factors on male reproductive fitness, making this an invaluable text for physicians treating patients for infertility, recurrent pregnancy loss, and developmental anomalies, as well as basic scientists studying embryogenesis and spermatogenesis.

Exploring the Biological Contributions to Human Health

Exploring the Biological Contributions to Human Health
  • Author : Institute of Medicine,Board on Health Sciences Policy,Committee on Understanding the Biology of Sex and Gender Differences
  • Publisher :Unknown
  • Release Date :2001-07-02
  • Total pages :288
  • ISBN : 0309132975
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Summary : It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers.

A Life (Un)Worthy of Living

A Life (Un)Worthy of Living
  • Author : Yael Hashiloni-Dolev
  • Publisher :Unknown
  • Release Date :2007-03-29
  • Total pages :195
  • ISBN : UVA:X030338374
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Summary : This book presents the findings of a study into the social shaping of reproductive genetics in Germany and Israel. The study reveals dramatic differences between German and Israeli societies in addressing the question of a life (un)worthy of living. A close analysis of the ways that these two societies handle the balance between the quality and sanctity of life illuminates controversies over reproductive genetics in an original and provocative way.

Perinatal Genetics

Perinatal Genetics
  • Author : Mary E Norton,Jeffrey A. Kuller,Lorraine Dugoff
  • Publisher :Unknown
  • Release Date :2019-01-23
  • Total pages :350
  • ISBN : 9780323530965
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Summary : Get a quick, expert overview of the fast-changing field of perinatal genetics with this concise, practical resource. Drs. Mary Norton, Jeffrey A. Kuller, Lorraine Dugoff, and George Saade fully cover the clinically relevant topics that are key to providers who care for pregnant women and couples contemplating pregnancy. It’s an ideal resource for Ob/Gyn physicians, maternal-fetal medicine specialists, and clinical geneticists, as well as midwives, nurse practitioners, and other obstetric providers. Provides a comprehensive review of basic principles of medical genetics and genetic counseling, molecular genetics, cytogenetics, prenatal screening options, chromosomal microarray analysis, whole exome sequencing, prenatal ultrasound, diagnostic testing, and more. Contains a chapter on fetal treatment of genetic disorders. Consolidates today’s available information and experience in this important area into one convenient resource.

Encyclopedia of Reproduction

Encyclopedia of Reproduction
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2018-06-29
  • Total pages :3868
  • ISBN : 9780128151457
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Summary : Encyclopedia of Reproduction, Second Edition comprehensively reviews biology and abnormalities, also covering the most common diseases in humans, such as prostate and breast cancer, as well as normal developmental biology, including embryogenesis, gestation, birth and puberty. Each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers, from advanced undergraduate students, to research professionals. Chapters also explore the latest advances in cloning, stem cells, endocrinology, clinical reproductive medicine and genomics. As reproductive health is a fundamental component of an individual’s overall health status and a central determinant of quality of life, this book provides the most extensive and authoritative reference within the field. Provides a one-stop shop for information on reproduction that is not available elsewhere Includes extensive coverage of the full range of topics, from basic, to clinical considerations, including evolutionary advances in molecular, cellular, developmental and clinical sciences Includes multimedia and interactive teaching tools, such as downloadable PowerPoint slides, video content and interactive elements, such as the Virtual Microscope

Creation Ethics

Creation Ethics
  • Author : David DeGrazia
  • Publisher :Unknown
  • Release Date :2014-10-29
  • Total pages :248
  • ISBN : 9780190232443
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Summary : The ethics of creating -- or declining to create -- human beings has been addressed in several contexts: debates over abortion and embryo research; literature on "self-creation"; and discussions of procreative rights and responsibilities, genetic engineering, and future generations. Here, for the first time, is a sustained, scholarly analysis of all of these issues -- a discussion combining breadth of topics with philosophical depth, imagination with current scientific understanding, argumentative rigor with accessibility. The overarching aim of Creation Ethics is to illuminate a broad array of issues connected with reproduction and genetics, through the lens of moral philosophy. With novel frameworks for understanding prenatal moral status and human identity, and exceptional fairness to those holding different views, David DeGrazia sheds new light on the ethics of abortion and embryo research, genetic enhancement and prenatal genetic interventions, procreation and parenting, and decisions that affect the quality of life of future generations. Along the way, he helpfully introduces personal identity theory and value theory as well as such complex topics as moral status, wrongful life, and the "nonidentity problem." The results include a subjective account of human well-being, a standard for responsible procreation and parenting, and a theoretical bridge between consequentialist and nonconsequentialist ethical theories. The upshot is a synoptic, mostly liberal vision of the ethics of creating human beings.