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Inflammation, Advancing Age and Nutrition

Inflammation, Advancing Age and Nutrition
  • Author : Irfan Rahman,Debasis Bagchi
  • Publisher :Unknown
  • Release Date :2013-09-03
  • Total pages :394
  • ISBN : 9780123978073
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Summary : The book provides a comprehensive overview to understanding the integrated impact of the concepts of cellular and molecular aspects, models, environmental factors, and lifestyle involved in premature aging. Additionally, it examines how functional food, dietary nutraceuticals or pharmacological compounds can reverse inflammation and premature aging based on personalized medicine. This book is a valuable resource for health professionals, scientists and researchers, nutritionists, health practitioners, students and for all those who wish to broaden their knowledge in the allied field. Includes models of aging, including worm, mouse and human Explores the relationship of inflammation with diseases, including ocular health, Alzheimer's and Parkinson's disease, and muscle health Encompasses a variety of lifestyle impacts, including diet, exercise and nutrition Includes suggested nutritional interventions

Allogeneic Mesenchymal Stem Cells as a Treatment for Aging Frailty

Allogeneic Mesenchymal Stem Cells as a Treatment for Aging Frailty
  • Author : Bryon A. Tompkins
  • Publisher :Unknown
  • Release Date :2017
  • Total pages :229
  • ISBN : OCLC:1154245079
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Summary : As life expectancy is projected to increase in the ensuing decades, individuals of older age continue to exceed the previous generation's lifespan. Advancing age is associated with a reduction in physical and mental functional capacity, and chronic inflammation is a major factor contributing to this decline. A heightened inflammatory state can lead to exhaustion, weakness, weight loss, slow gate speed, and an overall decrease in activity level. These phenotypes define the onset of the disease process known as frailty. Frailty is a growing epidemic, which severely undermines a person's ability to deal with outside stressors, and increases their rate of hospitalization, institutionalization, and mortality. Current interventions focus on preventative care by improving exercise capacity, strength, nutritional supplementation, diet, and mobility. However, a biological cure has heretofore remained elusive. Here, we introduce the novel therapeutic principle that mesenchymal stem cell (MSC) therapy may represent a safe, practical, and efficacious both the treatment and prevention of frailty in individuals of advancing age. To date, a phase I safety trial reveals an excellent safety profile and suggests that mesenchymal stem cells can ameliorate signs and symptoms of frailty. These early studies lay the groundwork for future large-scale clinical trials of this exciting and novel therapeutic concept that has the potential to expand health span in the aging population.

AUTOIMMUNE DIET AND RECOVERY PLAN

AUTOIMMUNE DIET AND RECOVERY PLAN
  • Author : Jennifer Michaels
  • Publisher :Unknown
  • Release Date :2013-12-30
  • Total pages :37
  • ISBN : 9781630226831
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Summary : Are you at risk for autoimmune disease? Do you feel frequently tired, irritable or under the weather? Are you experiencing achiness, brain fog or weight problems? Then it's time to take action. Has your doctor recently told you that an autoimmune test, such as a test for antinuclear antibodies (ANA), is equivocal, borderline, or positive? If so, you are at risk for autoimmune disease. Like an automobile that needs coolant and an oil change, this is the time to take action--fast! The AUTOIMMUNE DIET AND RECOVERY PLAN offers the information you're looking for, now. Traditional allopathic physicians offer powerful pharmaceutical therapies that can address some of the issues relating to an overly active immune system, but at a very great cost. These therapies, by depressing the immune system, do not treat the root cause of your problem and also increase the chances of contracting even more serious ailments, like cancer, by up to 400 hundred times. This book shares an up?to?date summary of research and available, natural treatments and therapies to use today.

Immunity and Inflammation in Health and Disease

Immunity and Inflammation in Health and Disease
  • Author : Shampa Chatterjee,Wolfgang Jungraithmayr,Debasis Bagchi
  • Publisher :Unknown
  • Release Date :2017-08-31
  • Total pages :476
  • ISBN : 9780128054024
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Summary : Immunity and Inflammation in Health and Disease: Emerging Roles of Nutraceuticals and Functional Foods in Immune Support provides a comprehensive description of the various pathways by which the vertebrate immune system works, the signals that trigger immune response and how fnew and novel nutraceuticals and functional foods, can be used to contain inflammation and also to boost immunity and immune health. Inflammation is a tool to fight pathogens and the vertebrate immune system has a very complex network of cells to achieve this. However inflammation that goes awry is also the leding cause of several diseases ranging from cardiovascular diseases to diabetes. This book covers the entire gamut from the various cellular players in the inflammation-immune response to its ramifications in terms of protection against pathogens as well as in onset of metabolic, aging and auto-immune related diseases. Finally, the balancing role of dietary nutrients between host defence and immune support is also showcased. The first three scetions explain the various components of the immune system and their modes of activation. The fourth section deals with the ramifications of a robust and execessive inflammatory response. The fifth section is focused on the association between nutrition and immunity and how deficiencies in certain nutrients may affect immunocompetence. The sixth section chapters represent a vision of paradigm shifts within the field and discusses possible future directions. This bool will be a valuable reference for researchers studying immune health either in academia, or in the nutraceutical or functional food industries. Product developers in nutraceutical, supplement, functional food, and health food companies will also appreciate the information presented here. Conceptualizes the key features in natural products which can boost immune function and immune health Explains the intricate mechanistic aspects and balance behind immune health Presents the pathophysiology of several diseases associated with immune system disruption

Nutrition and Immunity

Nutrition and Immunity
  • Author : Maryam Mahmoudi,Nima Rezaei
  • Publisher :Unknown
  • Release Date :2019-07-30
  • Total pages :515
  • ISBN : 9783030160739
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Summary : This volume provides readers with a systematic assessment of current literature on the link between nutrition and immunity. Chapters cover immunonutrition topics such as child development, cancer, aging, allergic asthma, food intolerance, obesity, and chronic critical illness. It also presents a thorough review of microflora of the gut and the essential role it plays in regulating the balance between immune tolerance and inflammation. Written by experts in the field, Nutrition and Immunity helps readers to further understand the importance of healthy dietary patterns in relation to providing immunity against disorders and offering readily available immunonutritional programming in clinical care. It will be a valuable resource for dietitians, immunologists, endocrinologists and other healthcare professionals.

Food as Medicine

Food as Medicine
  • Author : Maurice M. Iwu
  • Publisher :Unknown
  • Release Date :2016-11-25
  • Total pages :384
  • ISBN : 9781315354385
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Summary : This comprehensive book documents African plants used for functional and medicinal foods. It contains more than 60 detailed monographs of African foods, describing foods with various characteristics such as prebiotic, probiotic, satiety, immune modulation, stress-reduction, sports performance, mental acuity, sleep-supporting, metabolic syndrome, antioxidant, and unsaturated fats. Plant description, botanical names and synonyms, plant part used, habitat and distribution, folk use, nutritional content, and chemistry are all fully detailed. The book highlights indigenous African food processing technologies up to the modern era.

Nutrition in the Middle and Later Years

Nutrition in the Middle and Later Years
  • Author : Elaine B. Feldman
  • Publisher :Unknown
  • Release Date :2013-10-22
  • Total pages :352
  • ISBN : 9781483281025
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Summary : Nutrition in the Middle and Later Years focuses on the behavioral and biochemical aspects of eating geared to the population aged 45 or older. The selection first offers information on nutrition and lifestyle and nutritional requirements and the appropriate use of supplements. Topics include proteins, carbohydrates, fat soluble vitamins, minerals, status and aging, social isolation, and loss of income or reliance on fixed income. The text then elaborates on animal models in aging research and evaluation and treatment of obesity. The manuscript takes a look at alcoholism and nutritional factors in cardiovascular disease. Discussions focus on diet and atherosclerosis, general aspects of carbohydrate, lipid, and protein metabolism in the alcoholic, and management of elderly alcoholic. The text also examines the relationship of nutrition and cancer, nutrition and gastrointestinal tract disorders, and neurological manifestations of nutritional deficiencies. The selection is highly recommended for nutritionists and readers wanting to conduct studies on nutrition during the middle and later years.

Epigenetics of Aging and Longevity

Epigenetics of Aging and Longevity
  • Author : Alexey Moskalev,Alexander M. Vaiserman
  • Publisher :Unknown
  • Release Date :2017-11-17
  • Total pages :544
  • ISBN : 9780128110836
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Summary : Epigenetics of Aging and Longevity provides an in-depth analysis of the epigenetic nature of aging and the role of epigenetic factors in mediating the link between early-life experiences and life-course health and aging. Chapters from leading international contributors explore the effect of adverse conditions in early-life that may result in disrupted epigenetic pathways, as well as the potential to correct these disrupted pathways via targeted therapeutic interventions. Intergenerational epigenetic inheritance, epigenetic drug discovery, and the role of epigenetic mechanisms in regulating specific age-associated illnesses—including cancer and cardiovascular, metabolic, and neurodegenerative diseases—are explored in detail. This book will help researchers in genomic medicine, epigenetics, and biogerontology better understand the epigenetic determinants of aging and longevity, and ultimately aid in developing therapeutics to extend the human life-span and treat age-related disease. Offers a comprehensive overview of the epigenetic nature of aging, as well as the impact of epigenetic factors on longevity and regulating age-related disease Provides readers with clinical and epidemiological evidence for the role of epigenetic mechanisms in mediating the link between early-life experiences, life-course health and aging trajectory Applies current knowledge of epigenetic regulatory pathways towards developing therapeutic interventions for age-related diseases and extending the human lifespan

Molecular Basis and Emerging Strategies for Anti-aging Interventions

Molecular Basis and Emerging Strategies for Anti-aging Interventions
  • Author : Syed Ibrahim Rizvi,Ufuk Çakatay
  • Publisher :Unknown
  • Release Date :2018-11-02
  • Total pages :386
  • ISBN : 9789811316999
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Summary : This book describes the nature of aging, age-related disorders, and the molecular principles of emerging strategies for anti-aging interventions, while also discussing the discovery of targets for geroprotective drugs. Although significant medical advances in the treatment and eradication of life-threatening conditions such as cardiovascular and infectious disease have been made over the past five decades, the prevalence of age-related disorders still remains high in older populations. Intervening into aging is the next frontier in contemporary medicine, and will be of increasing importance over time, as other sources of poor health are combated more and more successfully. Given the universal interest in anti-aging strategies, the book will appeal to a very broad audience. It addresses a diverse range of anti-aging interventions – including stem cells, autophagy, senolytics, anti-inflammatory methods, and telomerase induction – that will be of interest to scientists and researchers from various disciplines in the life sciences.

Biotechnology

Biotechnology
  • Author : David P. Clark,Nanette J. Pazdernik
  • Publisher :Unknown
  • Release Date :2015-05-16
  • Total pages :850
  • ISBN : 9780123850164
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Summary : Biotechnology, Second Edition approaches modern biotechnology from a molecular basis, which has grown out of increasing biochemical understanding of genetics and physiology. Using straightforward, less-technical jargon, Clark and Pazdernik introduce each chapter with basic concepts that develop into more specific and detailed applications. This up-to-date text covers a wide realm of topics including forensics, bioethics, and nanobiotechnology using colorful illustrations and concise applications. In addition, the book integrates recent, relevant primary research articles for each chapter, which are presented on an accompanying website. The articles demonstrate key concepts or applications of the concepts presented in the chapter, which allows the reader to see how the foundational knowledge in this textbook bridges into primary research. This book helps readers understand what molecular biotechnology actually is as a scientific discipline, how research in this area is conducted, and how this technology may impact the future. Up-to-date text focuses on modern biotechnology with a molecular foundation Includes clear, color illustrations of key topics and concept Features clearly written without overly technical jargon or complicated examples Provides a comprehensive supplements package with an easy-to-use study guide, full primary research articles that demonstrate how research is conducted, and instructor-only resources

The Science of Hormesis in Health and Longevity

The Science of Hormesis in Health and Longevity
  • Author : Suresh I. S. Rattan,Marios Kyriazi
  • Publisher :Unknown
  • Release Date :2018-10-23
  • Total pages :326
  • ISBN : 9780128142547
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Summary : The Science of Hormesis in Health and Longevity provides a comprehensive review of mild stress-induced physiological hormesis and its role in the maintenance and promotion of health. Coverage includes the underlying mechanisms of hormesis, including details of stress-response signaling, an enriched environment, positive challenges and dose-response mechanisms, amongst others. Research from top experts is presented to provide suggestions for developing novel therapeutic strategies, along with lifestyle interventions to promote health and homoeostasis. Researchers in aging and physiology, gerontologists, clinicians and medical students will find this a valuable addition for their work. Provides a comprehensive, scholarly review of the current state of hormesis in physiology, health, disease and aging Includes multiple perspectives and in-depth analysis by top experts involved in cutting-edge research to provide developing, novel therapeutic strategies, as well as lifestyle interventions Offers a clear understanding of hormesis’ underlying mechanisms, including details of stress-response signaling, an enriched environment, positive challenges, dose-response mechanisms, and more

Nutrition for the Middle Aged and Elderly

Nutrition for the Middle Aged and Elderly
  • Author : Nancy E. Bernhardt,Artur M. Kasko
  • Publisher :Unknown
  • Release Date :2008
  • Total pages :492
  • ISBN : 1604561467
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Summary : The ageing process changes body composition and thus nutritional status changes as one gets older. At the same time the body becomes more susceptible to diseases and diet becomes an even more significant or at least visibly significant than in earlier years. Moreover, there is frequently socio-economic downward drifting in this age group making nutritious foods more difficult to afford. This book presents the latest research in this vital field.

Muscle and Exercise Physiology

Muscle and Exercise Physiology
  • Author : Jerzy A. Zoladz
  • Publisher :Unknown
  • Release Date :2018-11-05
  • Total pages :618
  • ISBN : 9780128145944
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Summary : Muscle and Exercise Physiology is a comprehensive reference covering muscle and exercise physiology, from basic science to advanced knowledge, including muscle power generating capabilities, muscle energetics, fatigue, aging and the cardio-respiratory system in exercise performance. Topics presented include the clinical importance of body responses to physical exercise, including its impact on oxygen species production, body immune system, lipid and carbohydrate metabolism, cardiac energetics and its functional reserves, and the health-related effects of physical activity and inactivity. Novel topics like critical power, ROS and muscle, and heart muscle physiology are explored. This book is ideal for researchers and scientists interested in muscle and exercise physiology, as well as students in the biological sciences, including medicine, human movements and sport sciences. Contains basic and state-of-the-art knowledge on the most important issues of muscle and exercise physiology, including muscle and body adaptation to physical training, the impact of aging and physical activity/inactivity Provides both the basic and advanced knowledge required to understand mechanisms that limit physical capacity in both untrained people and top class athletes Covers advanced content on muscle power generating capabilities, muscle energetics, fatigue and aging

Diet and Immune Function

Diet and Immune Function
  • Author : Elizabeth A Miles,Philip Calder,Caroline E Childs
  • Publisher :Unknown
  • Release Date :2020-05-22
  • Total pages :314
  • ISBN : 9783039216123
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Summary : Supporting initiation, development and resolution of appropriate immune responses is key to survival. Many nutrients and dietary components have been purported to have a role in supporting optimal immune function. This is vital throughout the life course, from the development and programming of the immune system in early life, to supporting immunity and reducing chronic inflammation in older people. In this special issue of Nutrients, we examine the evidence for the role of diet and dietary components in promoting protective immunity.

Exercise as a Countermeasure to Human Aging

Exercise as a Countermeasure to Human Aging
  • Author : Bradley Elliott,Lawrence D. Hayes,David C. Hughes,Martin Burtscher
  • Publisher :Unknown
  • Release Date :2020-11-12
  • Total pages :229
  • ISBN : 9782889660100
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Summary :

Recent Advances in Immunology to Target Cancer, Inflammation and Infections

Recent Advances in Immunology to Target Cancer, Inflammation and Infections
  • Author : Jagat Kanwar
  • Publisher :Unknown
  • Release Date :2012-05-09
  • Total pages :534
  • ISBN : 9789535105923
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Summary : Immunology is the branch of biomedical sciences to study of the immune system physiology both in healthy and diseased states. Some aspects of autoimmunity draws our attention to the fact that it is not always associated with pathology. For instance, autoimmune reactions are highly useful in clearing off the excess, unwanted or aged tissues from the body. Also, generation of autoimmunity occurs after the exposure to the non-self antigen that is structurally similar to the self, aided by the stimulatory molecules like the cytokines. Thus, a narrow margin differentiates immunity from auto-immunity as already discussed. Hence, finding answers for how the physiologic immunity turns to pathologic autoimmunity always remains a question of intense interest. However, this margin could be cut down only if the physiology of the immune system is better understood. The individual chapters included in this book will cover all the possible aspects of immunology and pathologies associated with it. The authors have taken strenuous effort in elaborating the concepts that are lucid and will be of reader's interest.

Immunonutrition

Immunonutrition
  • Author : Bharat B. Aggarwal,David Heber
  • Publisher :Unknown
  • Release Date :2014-03-17
  • Total pages :368
  • ISBN : 9781466503861
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Summary : The interaction of immune function and nutrition underlies the low-grade chronic inflammation involved in the etiology of many common obesity-associated and age-related chronic disease conditions. This close interaction is the genesis of the term immunonutrition, which represents a new interdisciplinary field of nutritional and medical research. Immunonutrition: Interactions of Diet, Genetics, and Inflammation introduces the breadth of this field, which implicates nutrition in both immune function and in the etiology, prevention, and treatment of common diseases influenced by inflammation and immune imbalance, including obesity, diabetes, heart disease, asthma, autoimmune diseases, and common forms of cancer. The book begins by reviewing the basic mechanisms of immunity and cellular mechanisms of cytokine activation. It discusses the effects of dietary fat intake and changes in Western diet and lifestyle linked to inflammation. It also describes the interaction of genetics and environment in the modulation of immune function and inflammation, and addresses exercise and skeletal muscle as an endocrine and immune organ. The book reviews the entire spectrum of inflammation and cancer from causation to its role in tumor therapy. It examines abdominal obesity and metabolic diseases, interactions between nutrition and autoimmunity in systemic lupus erythematosus and rheumatoid arthritis, and inflammation associated with type 2 diabetes, heart disease, kidney disease, Alzheimer’s disease, and asthma. Considering potential nutrition-based treatments, the book explores approaches for reducing abdominal obesity, anti-inflammatory effects of phytochemicals, practical strategies for increasing fruit and vegetable intake, and anti-inflammatory properties of spice phytonutrients. In addition, it explores how uninformed food choices related to fats and oils create a balance of tissue-selective signals that produce harmful health outcomes and how to restore a healthy balance.

Nutrition and Bone Health

Nutrition and Bone Health
  • Author : Michael F. Holick,Jeri W. Nieves
  • Publisher :Unknown
  • Release Date :2014-12-13
  • Total pages :718
  • ISBN : 9781493920013
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Summary : This newly revised edition contains updated versions of all of the topics that were in the first edition and has been substantially expanded with an additional 5 chapters. Each chapter includes information from the most up-to-date research on how nutritional factors can affect bone health, written with an evidence-based focus and complete with comprehensive references for each subject. Nutrition and Bone Health, second edition covers all aspects of nutrition and the skeleton, from the history and fundamentals, to the effects of macronutrients, minerals, vitamins, and supplements, and even covers the effects of lifestyle, the different life stages, and nutrition-related disorders and secondary osteoporosis. New chapters include HIV & AIDs and the skeleton, celiac disease and bone health, and nutrition and bone health in space. Nutrition and Bone Health, second edition is a necessary resource for health care professionals, medical students, graduate students, dietitians, and nutritionists who are interested in how nutrition affects bone health during all stages of life.

Conn's Handbook of Models for Human Aging

Conn's Handbook of Models for Human Aging
  • Author : Jeffrey L. Ram,P. Michael Conn
  • Publisher :Unknown
  • Release Date :2018-04-05
  • Total pages :1218
  • ISBN : 9780128113547
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Summary : Conn's Handbook of Models for Human Aging, Second Edition, presents key aspects of biology, nutrition, factors affecting lifespan, methods of age determination, use in research and the disadvantages/advantages of use. Using a multidisciplinary approach, this updated edition is designed as the only comprehensive, current work that covers the diversity in aging models. Chapters on comparative models explore age-related diseases, including Alzheimer's, joint disease, cataracts, cancer and obesity. Also included are new tricks and approaches not available in primary publications. This must-have handbook is an indispensable resource for researchers interested in the mechanisms of aging, gerontologists, health professionals, allied health practitioners and students. Combines both the methods of study for human aging and animal models Provides a historical overview and discussion of model availability, key methods and ethical issues Contains over 200 full color illustrations

Integrated Role of Nutrition and Physical Activity for Lifelong Health

Integrated Role of Nutrition and Physical Activity for Lifelong Health
  • Author : Karsten Koehler,Clemens Drenowatz
  • Publisher :Unknown
  • Release Date :2019-07-16
  • Total pages :202
  • ISBN : 9783039212118
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Summary : As computer and space technologies have been developed, geoscience information systems (GIS) and remote sensing (RS) technologies, which deal with the geospatial information, have been rapidly maturing. Moreover, over the last few decades, machine learning techniques including artificial neural network (ANN), deep learning, decision tree, and support vector machine (SVM) have been successfully applied to geospatial science and engineering research fields. The machine learning techniques have been widely applied to GIS and RS research fields and have recently produced valuable results in the areas of geoscience, environment, natural hazards, and natural resources. This book is a collection representing novel contributions detailing machine learning techniques as applied to geoscience information systems and remote sensing.

Nutrition Across the Lifespan for Healthy Aging

Nutrition Across the Lifespan for Healthy Aging
  • Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Food and Nutrition Board,Food Forum
  • Publisher :Unknown
  • Release Date :2017-05-11
  • Total pages :168
  • ISBN : 9780309457514
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Summary : In September 2016, the National Academies of Sciences, Engineering, and Medicine convened a workshop to examine trends and patterns in aging and factors related to healthy aging in the United States, with a focus on nutrition, and how nutrition can sustain and promote healthy aging, not just in late adulthood, but beginning in pregnancy and early childhood and extending throughout the lifespan. Participants discussed the role of nutrition in the aging process at various stages in life, changes in organ systems over the lifespan and changes that occur with age related to cognitive, brain, and mental health, and explored opportunities to move forward in promoting healthy aging in the United States. This publication summarizes the presentations and discussions from the workshop.