Download Inflammation In Heart Failure Book PDF

Download full Inflammation In Heart Failure books PDF, EPUB, Tuebl, Textbook, Mobi or read online Inflammation In Heart Failure anytime and anywhere on any device. Get free access to the library by create an account, fast download and ads free. We cannot guarantee that every book is in the library.

Inflammation in Heart Failure

Inflammation in Heart Failure
  • Author : Matthijs Blankesteijn,Raffaele Altara
  • Publisher :Unknown
  • Release Date :2014-12-05
  • Total pages :220
  • ISBN : 9780128004852
GET BOOK HERE

Summary : Inflammation in Heart Failure, edited by W. Matthijs Blankesteijn and Raffaele Altara, is the first book in a decade to provide an in-depth assessment on the causes, symptoms, progression and treatments of cardiac inflammation and related conditions. This reference uses two decades of research to introduce new methods for identifying inflammatory benchmarks from early onset to chronic heart failure and specifically emphasizes the importance of classifying at-risk subgroups within large populations while determining the patterns of cytokines in such classifications. Further, the book details clinical applications of the pathophysiological mechanisms of heart failure, diagnosis and therapeutic strategies. Inflammation in Heart Failure’s breadth of subject matter, easy-to-follow structure, portability, and high-quality illustrations create an accessible benefit for researchers, clinicians and students. Presents updated information and research on the relevant inflammatory mediators of heart failure to aid in targeting future translational research as well as the improvement of early diagnosis and treatment Provides research into better understanding the different inflammatory mediators that signal the underlying diseases that potentially lead to heart failure Contains 20 years of research, offering a brief overview of the topic leading to current opinions on, and treatment of, heart failure Provides a structured, systematic and balanced overview of the role of inflammation in heart failure making it a useful resource for researchers and clinicians, as well as those studying cardiovascular diseases

Inflammation in Heart Failure

Inflammation in Heart Failure
  • Author : Matthijs Blankesteijn,Raffaele Altara
  • Publisher :Unknown
  • Release Date :2014-12-05
  • Total pages :220
  • ISBN : 9780128004852
GET BOOK HERE

Summary : Inflammation in Heart Failure, edited by W. Matthijs Blankesteijn and Raffaele Altara, is the first book in a decade to provide an in-depth assessment on the causes, symptoms, progression and treatments of cardiac inflammation and related conditions. This reference uses two decades of research to introduce new methods for identifying inflammatory benchmarks from early onset to chronic heart failure and specifically emphasizes the importance of classifying at-risk subgroups within large populations while determining the patterns of cytokines in such classifications. Further, the book details clinical applications of the pathophysiological mechanisms of heart failure, diagnosis and therapeutic strategies. Inflammation in Heart Failure’s breadth of subject matter, easy-to-follow structure, portability, and high-quality illustrations create an accessible benefit for researchers, clinicians and students. Presents updated information and research on the relevant inflammatory mediators of heart failure to aid in targeting future translational research as well as the improvement of early diagnosis and treatment Provides research into better understanding the different inflammatory mediators that signal the underlying diseases that potentially lead to heart failure Contains 20 years of research, offering a brief overview of the topic leading to current opinions on, and treatment of, heart failure Provides a structured, systematic and balanced overview of the role of inflammation in heart failure making it a useful resource for researchers and clinicians, as well as those studying cardiovascular diseases

Inflammation and Cardiac Diseases

Inflammation and Cardiac Diseases
  • Author : Giora Z. Feuerstein,Peter Libby,Douglas L. Mann
  • Publisher :Unknown
  • Release Date :2012-12-06
  • Total pages :419
  • ISBN : 9783034880473
GET BOOK HERE

Summary : Heart failure research is a most active area of research in academic, industrial and government-sponsored research and receives intense clinical attention. The recent recognition that inflammation is a risk factor and prognostic factor for heart disease has laid ground for preventive medicine and even anti-infective strategies in prevention and treatment of heart failure. Provides a new perspective on the etiology of cardiac failure Covers the latest developments Discusses future treatments for heart failure Ideal for researchers and clinicians

Chronic Viral and Inflammatory Cardiomyopathy

Chronic Viral and Inflammatory Cardiomyopathy
  • Author : Heinz-Peter Schultheiss,Joachim-Friedrich Kapp,Georg Grötzbach
  • Publisher :Unknown
  • Release Date :2007-01-19
  • Total pages :370
  • ISBN : 9783540308225
GET BOOK HERE

Summary : The interconnectedness of genetics and susceptibility to disease, viral and non-viral inflammation, and the role of immunity and the development of autoimmunity is a fascinating and much discussed topic in cardiomyopathy. This publication constitutes the outcome of an ESRF meeting held together with the German Research Foundation. Clinical researchers, immunologists, virologists and molecular biologists provide the latest findings in their fields, advancing our understanding of what causes chronic viral and inflammatory cardiomyopathy, why it affects a subset of individuals while sparing the majority, how we can develop better therapies, and whether the disease can be prevented. Special emphasis is placed on the role of viruses in the aetiology and pathogenesis of cardiomyopathy. The editors are convinced that the broad spectrum covered by this state-of-the-art publication will be of exceptional value to its readers.

Inflammatory Cardiomyopathy (DCMi) - Pathogenesis and Therapy

Inflammatory Cardiomyopathy (DCMi) - Pathogenesis and Therapy
  • Author : Heinz-Peter Schultheiss,Michel Noutsias
  • Publisher :Unknown
  • Release Date :2011-01-30
  • Total pages :294
  • ISBN : 3764383526
GET BOOK HERE

Summary : Cardiomyopathy is one of the most frequent causes of heart failure. It is often associated with inadequate heart pumping or other heart function abnormalities. There are many different causes of the disease, therefore many different kinds of cardiomyopathies exist. This volume, written by a leading expert, focuses on inflammatory CM, belonging to the Dilated Cardiomyopathies (DCMi). It covers epidemiology/prognosis, pathology, immunology, diagnosis and treatment strategies.

Cardiac Remodeling and Failure

Cardiac Remodeling and Failure
  • Author : Pawan K. Singal,Ian M.C. Dixon,Naranjan S. Dhalla,Lorrie A. Kirshenbaum
  • Publisher :Unknown
  • Release Date :2003-02-28
  • Total pages :545
  • ISBN : 1402071779
GET BOOK HERE

Summary : The importance of the developmental approach for experimental and clinical cardiology is indisputable. Clinical-epidemiological studies have clearly shown that the risk factors of serious cardiovascular diseases, such as atherosclerosis and ischemic heart disease, are already present during the early phases of ontogenetic development. Furthermore, congenital cardiovascular malformations remain the single largest cause of infant mortality from congenital defects in industrial countries. It is therefore not surprising that the interest of theoretical and clinical cardiologists in the developmental approach keeps increasing. Advances in molecular biology accelerated this trend substantially. This book is based on contributions presented at the international symposium The Developing Heart in Prague in May 2000. It is our contention that the biological, electrophysiological, morphological, functional, biochemical and functional approaches employed by distinguished scientists worldwide will provide the reader with a global picture for changes characterizing the developing heart. It should stimulate the curiosity of cardiovascular scientists in gaining insight into the mechanisms of normal and pathological development.

The Heart in Rheumatic, Autoimmune and Inflammatory Diseases

The Heart in Rheumatic, Autoimmune and Inflammatory Diseases
  • Author : Udi Nussinovitch
  • Publisher :Unknown
  • Release Date :2017-02-10
  • Total pages :766
  • ISBN : 9780128032688
GET BOOK HERE

Summary : The prevalence of autoimmune diseases and rheumatic conditions is constantly increasing. Autoimmune diseases affect approximately 7-10% of the population of the United States, while more than 50,000,000 American adults suffer from some type of arthritis. The Heart in Rheumatic, Autoimmune and Inflammatory Diseases examines the complex mechanisms relating to cardiac diseases from a pathophysiological and clinical point of view. Autoimmune rheumatic diseases can affect the coronary vessels, myocardium, pericardium, heart valves and the conduction system. The diagnosis of these unique cardiac complications necessitates medical awareness and a high index of suspicion. Increased risk of advanced atherosclerosis plays a pivotal role in the development of cardiac diseases in systemic, rheumatic and autoimmune illnesses. Yet, other complex immune medicated mechanisms may contribute to the pathogenesis. Patients' optimal care requires coordination between the primary caregiver, the rheumatologist, immunologist and cardiologist. Screening for cardiovascular risk factors, recognition of high-risk patients and identification of subclinical cardiac conditions are of great importance. Moreover, regulation of inflammation, as well as abnormal immune responses and the initiation of early treatments should be the focus of patient management. A continuous attempt to identify novel therapeutic targets and change the natural history of the underlying disease and its cardiac manifestations is in progress. The book aims at providing the readers with a state of the art collection of up to date information regarding clinically important topics based on experts' perspectives. This book was a result of an extended coordinated collaboration of one-hundred and fifty-four distinguished scientists from thirty-one countries around the globe. A review of common, as well as unusual (yet clinically significant) medical cardiac complications of prevalent rheumatic, autoimmune and inflammatory diseases. Focuses on aspects of pathophysiological processes, clinical presentations, screening tests, prognostic implications and novel therapeutic approaches. Presents an up-to-date “level of evidence and “strengths of recommendations for suggested therapies and reviews all randomized clinical trials, meta-analyses and other supporting published clinical findings.

Cardiomyopathies

Cardiomyopathies
  • Author : Kaan Kırali
  • Publisher :Unknown
  • Release Date :2017-04-12
  • Total pages :470
  • ISBN : 9789535130390
GET BOOK HERE

Summary : Cardiomyopathies are the most featured cardiac pathologies in the twenty-first century, that threaten public health and burden healthcare budgets. This book is composed of the main topics on pathophysiology, general forms and specific types of cardiomyopathies and it also introduces new research in the field. Specific forms with or without genetic inheritance are discussed separately to attract the readers' attention on these topics. Well-known medical follow-up strategies occur ineffective at the end-stage heart failure, however, new surgical approaches can be an alternative for these patients to get a chance at the last crossroad and to improve their life quality and survival and also to gain or prolong time until possible heart transplantation.

Stage B, a Pre-cursor of Heart Failure, An Issue of Heart Failure Clinics - E-Book

Stage B, a Pre-cursor of Heart Failure, An Issue of Heart Failure Clinics - E-Book
  • Author : Jay N. Cohn,Gary S. Francis
  • Publisher :Unknown
  • Release Date :2012-01-28
  • Total pages :187
  • ISBN : 9781455742844
GET BOOK HERE

Summary : In the joint American College of Cardiology /American Heart Association classification system, Stage B heart failure refers to patients with structural heart disease but no symptoms of heart failure. Preventing progression of heart failure in Stage B patients is a central concern to heart failure specialists, so two issues have been devoted to this topic. Part I focuses on an understanding of structural heart disease and the factors that cause progression from risk of heart failure to development of structural changes.

Heart Failure: A Companion to Braunwald's Heart Disease E-Book

Heart Failure: A Companion to Braunwald's Heart Disease E-Book
  • Author : G. Michael Felker,Douglas L. Mann
  • Publisher :Unknown
  • Release Date :2019-02-06
  • Total pages :784
  • ISBN : 9780323609883
GET BOOK HERE

Summary : Up-to-date, authoritative and comprehensive, Heart Failure, 4th Edition, provides the clinically relevant information you need to effectively manage and treat patients with this complex cardiovascular problem. This fully revised companion to Braunwald’s Heart Disease helps you make the most of new drug therapies such as angiotensin receptor neprilysin inhibitors (ARNIs), recently improved implantable devices, and innovative patient management strategies. Led by internationally recognized heart failure experts Dr. G. Michael Felker and Dr. Douglas Mann, this outstanding reference gives health care providers the knowledge to improve clinical outcomes in heart failure patients. Focuses on a clinical approach to treating heart failure, resulting from a broad variety of cardiovascular problems. Covers the most recent guidelines and protocols, including significant new updates to ACC, AHA, and HFSA guidelines. Covers key topics such as biomarkers and precision medicine in heart failure and new data on angiotensin receptor neprilysin inhibitors (ARNIs). Contains four new chapters: Natriuretic Peptides in Heart Failure; Amyloidosis as a Cause of Heart Failure; HIV and Heart Failure; and Neuromodulation in Heart Failure. Covers the pathophysiological basis for the development and progression of heart failure. Serves as a definitive resource to prepare for the ABIM’s Heart Failure board exam. 2016 British Medical Association Award: First Prize, Cardiology (3rd Edition).

Hidden Causes of Heart Attack and Stroke

Hidden Causes of Heart Attack and Stroke
  • Author : Christian Wilde
  • Publisher :Unknown
  • Release Date :2003-04
  • Total pages :408
  • ISBN : 0972495908
GET BOOK HERE

Summary : Written to empower you to interface intelligently with your doctors in protecting yourself and your family from America's number one killer. Written in everyday language, this book prepares you to discuss the cutting edge blood tests for C-reactive protein, inherited and acquired hidden risk factors and how to neutralize them by natural means. Rarely has a book drawn such enthusiastic endorsements from leaders in cardiology, even recommended for doctors. HEA000000

Heart Failure: A Companion to Braunwald's Heart Disease E-book

Heart Failure: A Companion to Braunwald's Heart Disease E-book
  • Author : Douglas L. Mann
  • Publisher :Unknown
  • Release Date :2010-11-11
  • Total pages :928
  • ISBN : 9781437703634
GET BOOK HERE

Summary : Dr. Douglas L. Mann, one of the foremost experts in the field, presents the 2nd Edition of Heart Failure: A Companion to Braunwald’s Heart Disease. This completely reworked edition covers the scientific and clinical guidance you need to effectively manage your patients and captures the dramatic advances made in the field over the last five years. Now in full color, this edition features eleven new chapters, including advanced cardiac imaging techniques, use of biomarkers, cell-based therapies and tissue engineering, device therapies, and much more. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Compatible with Kindle®, nook®, and other popular devices. Use this Braunwald’s companion as the definitive source to prepare for the ABIM’s new Heart Failure board exam. Access the fully searchable contents of the book online at Expert Consult. This edition includes 67 new authors, who are experts in the field of heart failure Stay on the cutting edge with new chapters on: The latest practice guidelines for medical and device therapy Hemodynamic assessment of heart failure Contemporary medical therapy for heart failure patients with reduced and preserved ejection fraction Biomarkers in heart failure Pulmonary hypertension Management of co-morbidities in heart failure Mechanical cardiac support devices Get up to speed with the latest clinical trials, as well as how they have influenced current practice guidelines Explore what’s changing in key areas such as basic mechanisms of heart failure, genetic screening, cell and gene therapies, pulmonary hypertension, heart failure prevention, co-morbid conditions, telemedicine/remote monitoring, and palliative care

Heart Failure in the Child and Young Adult

Heart Failure in the Child and Young Adult
  • Author : John L Jefferies,Anthony C Chang,Joseph W Rossano,Robert E Shaddy,Jeffrey A Towbin
  • Publisher :Unknown
  • Release Date :2017-12-05
  • Total pages :824
  • ISBN : 9780128026137
GET BOOK HERE

Summary : Heart Failure in the Child and Young Adult: From Bench to Bedside combines multiple etiologies for pediatric heart failure, including congenital heart disease, cardiomyopathies, infectious diseases and metabolic abnormalities. This comprehensive resource combines research from multiple contributors with current guidelines to bridge the knowledge gap for the recognition and management of heart failure in children. Coverage begins with the basic science of heart failure, then progresses through diagnosis, management, treatment and surgery, finally concluding with advanced special topics, including genetics, self-management and nanomedicine. Provides coverage of the basic science of heart failure, its epidemiology and economic aspects, outpatient and inpatient management, and advanced therapies, including mechanical circulatory support and heart transplantation Combines cutting-edge research with current guidelines from the field

Heart Failure: New Insights for the Healthcare Professional: 2011 Edition

Heart Failure: New Insights for the Healthcare Professional: 2011 Edition
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2012-01-09
  • Total pages :269
  • ISBN : 9781464900679
GET BOOK HERE

Summary : Heart Failure: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Heart Failure. The editors have built Heart Failure: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Heart Failure in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Heart Failure: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Metabolism and Immune Tolerance

Metabolism and Immune Tolerance
  • Author : Duncan Howie,Claudio Mauro
  • Publisher :Unknown
  • Release Date :2019-01-21
  • Total pages :229
  • ISBN : 9782889457250
GET BOOK HERE

Summary : Historically the study of the immune system and metabolism have been two very separate fields. In recent years, a growing literature has emerged illustrating how the multiple processes of cellular metabolism are intricately linked to several aspects of immune function and development. This Research Topic covers recent progress in the field now known as “Immunometabolism” and the role of metabolism in immune tolerance. Immune tolerance is operationally defined as a state where a host’s immune system is balanced such that although self-reactive lymphocytes are present, they are kept in check by immune regulation. Perturbations to this homeostasis may result in self-reactive lymphocytes gaining the upper hand and mediating auto-immune disease. Maintenance of immune tolerance involves a large cast of different cell types including effector T cells, regulatory T cells, B cells, stromal cells, dendritic cells and macrophages. Intracellular pathways and individual enzymes of metabolism have been shown to be harnessed by cells of both the adaptive and innate immune system to allow particular immune functions to be achieved. Examples include metabolic enzymes serving ‘moonlighting’ functions in mRNA translation, gene splicing, and kinase activation. Other examples include the requirement for de novo fatty acid synthesis for differentiation into Th17 effectors and CD8 memory T cells or products of the TCA cycle promoting pro-inflammatory cytokine production. Likewise, the availability of extracellular metabolic substrates has a large impact on the maintenance of local immune tolerance. For example, there are different requirements for glucose, glutamine and fatty acids for effector versus regulatory T cell development. Also tolerogenic dendritic cells mediate lowering of extracellular essential amino acids by their enhanced catabolism, promoting the induction of regulatory T cells. The purpose of this Research Topic is to provide an update on the current understanding of the multiple roles for metabolism in regulating the immune system.

Diagnosis and Treatment of Myocarditis

Diagnosis and Treatment of Myocarditis
  • Author : Jose Milei,Giuseppe Ambrosio
  • Publisher :Unknown
  • Release Date :2013-05-08
  • Total pages :208
  • ISBN : 9789535110828
GET BOOK HERE

Summary : Myocarditis is a clinical syndrome, most frequently of infectious etiology, that occurs with a broad range of relatively non-specific symptoms, and consists of an inflammatory process of the heart with necrosis and degeneration of the myocardium by inflammatory infiltration of immune cells. The infection can cause direct injury of cardiomyocytes as well as immune-mediated destruction of the myocardium, leading to cardiac dysfunction. In this book, the broad aspects of myocarditis are fully presented by leading international experts. The texts are devoted to both clinical aspects and pathophysiology, and they present comprehensive reviews of the causes of myocarditis, its classification, diagnosis, and treatment, as well as myocarditis in special populations such as pediatric, peripartum and chronic chagasic myocarditis.

Chagas Disease

Chagas Disease
  • Author : Veeranoot Nissapatorn,Helieh S. Oz
  • Publisher :Unknown
  • Release Date :2018-09-12
  • Total pages :238
  • ISBN : 9781789236583
GET BOOK HERE

Summary : This book contains 11 chapters of significant and updated materials on what we know and what we lack and need in better understanding of Trypanosoma cruzi - a parasite that never dies - and the consequences of Chagas disease as one of the most important neglected parasitic diseases threatening the global health and wellbeing. This book is intended to increase the readers' enthusiasm to explore the four sections of the contents: Section 1 begins with biochemistry, pathophysiology, histo-immunological study, and findings to assist in the diagnosis; Section 2 further investigates the role of vector in propagation of the parasite, the intensity on epidemiology, and the severity on clinical aspects, which help us to be well perceived on the course of disease; Section 3 is seeking beyond modern medicine and what lays in the nature that helps fight against this parasite; and the last section, Section 4, deals with the impacts of public health problem and the control strategies on Chagas disease.

Pharmacologic Approaches to Heart Failure, An Issue of Heart Failure Clinics,

Pharmacologic Approaches to Heart Failure, An Issue of Heart Failure Clinics,
  • Author : Kirkwood F. Adams
  • Publisher :Unknown
  • Release Date :2014-10-28
  • Total pages :137
  • ISBN : 9780323326124
GET BOOK HERE

Summary : This issue of Heart Failure Clinics examines the pharmacologic approaches to heart failure: optimizing established therapy with a look toward future agents. Topics include the pathophysiologic foundation for the pharmacologic treatment of heart failure, treatment of heart failure with reducted ejection fraction and preserved ejection fraction, treatment of acute heart failure, investigational treatments, and the role of congestive heart failure medications following left ventricular assist device.

Cardiomyopathies and Heart Failure

Cardiomyopathies and Heart Failure
  • Author : Akira Matsumori
  • Publisher :Unknown
  • Release Date :2003-07-31
  • Total pages :531
  • ISBN : 1402074387
GET BOOK HERE

Summary : Heart failure is a major, cause of death worldwide, most frequently secondary toacardiomyopathicdisorder. The rolesofviruses, immunity, cytokines and genetics as sources of heart failure have been relatively understated in the rapidly developing world of clinical cardiology. Yet, great progress in molecular biology and the recent application of new techniquesto studiesoftheetiologyandpathogenesisofcardiomyopathies and heart failure has shed new light in an area ready to undergo major developmentsandadvances. This book is an effort to present an up-to-date account of eXIstmg knowledge, includingrecentdevelopmentsinthisfield. Chapterscovering severaldisciplinesincludingbiochemistry, immunology, molecularbiology, virology, epidemiologyandclinicalmedicinehavebeenincluded, offeringa "bench-to-bedside"and"bedside-to-bench"criticalreviewofeveryaspects of heart failure and cardiomyopathies, by world renowned, expert researchers and clinicians. These opinion leaders review all significant advances in our understandingofheart failure and cardiomyopathies, and describe theimprovements indiagnosis and treatment that areexpectedto optimize the overall management of patients. The identification of establishedornewlyrecognizedmolecules, cytokines, viruses, andgenes, as well as an understandingofthe mechanisms by which these factors may cause cardiomyopathic disorders and induce heart failure depends on a multidisciplinaryapproachwhichthisbookattemptstouniquelyencompass. Therefore, wehopethatitwillbeanimportantresource, notonlyforclinical cardiologists, butalso forgeneralpractitioners, pediatriciansandspecialists in infectious diseases, as well as trainees and graduates in biochemistry, immunology, genetics, molecular biology, virology, pharmacology, and epidemiology. AkiraMatsumori, MD, PhD Ie INTRODUCTORYCHAPTER CARDIOMYOPATHIESANDHEARTFAILURE Biomolecular, InfectiousandImmuneMechanisms AkiraMatsumori, MD, PhD DepartmentofCardiovascularMedicine KyotoUniversityGraduateSchoolofMedicine Kyoto, Japan 1 SUMMARY Theclinicalpresentationofviralmyocarditisisvariable. Whenmyocardial necrosis is diffuse, congestive heart failure develops, and later, dilated cardiomyopathy. If the myocardial lesions are localized, a ventricular aneurysmforms. Whencomplicatedbyarrhythmias, myocarditispresentsas arrhythmogenic right ventricular cardiomyopathy. When myocardial necrosisislocalizedtothesubendocardialregion, restrictivecardiomyopathy may develop. While it has not been established that hypertrophic cardiomyopathy maybeacomplicationofviral myocarditis, asymmetrical septal hypertrophy has, in fact, sometimesbeen observed in patients with myocarditis. TheimportanceofhepatitisCvirusinfectionhasrecentlybeen notedinpatientswithmyocarditis, dilatedandhypertrophiccardiomyopath

Exercise and Rehabilitation in Heart Failure, An Issue of Heart Failure Clinics,

Exercise and Rehabilitation in Heart Failure, An Issue of Heart Failure Clinics,
  • Author : Ross Arena
  • Publisher :Unknown
  • Release Date :2014-12-26
  • Total pages :201
  • ISBN : 9780323341936
GET BOOK HERE

Summary : This multidisciplinary issue of Heart Failure Clinics examines a critical element in the management and treatment of heart failure (HF)—exercise and rehabilitation. Topics include the reversal of HF-associated pathophysiology with exercise; quantifying function; prognosis; rehabilitation practice patterns in the United States, Canada, South America, Asia, and Europe; special considerations such as obesity, high-intensity interval training, inspiratory muscle training, and technology to promote and increase physical activity.

IL-17, IL-22 and Their Producing Cells: Role in Inflammation and Autoimmunity

IL-17, IL-22 and Their Producing Cells: Role in Inflammation and Autoimmunity
  • Author : Valérie Quesniaux,Bernhard Ryffel,Franco Di Padova
  • Publisher :Unknown
  • Release Date :2012-12-13
  • Total pages :354
  • ISBN : 9783034805223
GET BOOK HERE

Summary : The knowledge of Th17 cells and other cell populations which secrete IL-17A, and/or IL-22 has expanded tremendously since the publication of the first edition “Th17 Cells: Role in Inflammation and Autoimmune Disease” in 2008. The present volume has been completely revised with the addition of new chapters on the IL-17 receptor family and signaling, and an in-depth review of IL-22 and innate lymphoid cells. The differentiation of naïve T cells into regulatory T cells and Th17 cells as well as the plasticity of Th17 cells is discussed. The role of IL-22 in cutaneous inflammation including psoriasis has been reviewed. In addition, the volume contains critical updates on autoimmunity, organ transplantation, tumor immunology and genetic mouse models for mechanistic studies. Lastly, the latest clinical progress in neutralizing antibodies to IL-17A, IL-17RA not only confirms the therapeutic promise foreseen in 2008, but also improves our knowledge of the pathogenesis of autoimmune diseases. In summary, this is a timely update and important review of the clinical and experimental aspects of IL-17, IL-22 and their producing cells.