Download Mechanisms Of Cell Death And Opportunities For Therapeutic Development Book PDF

Download full Mechanisms Of Cell Death And Opportunities For Therapeutic Development books PDF, EPUB, Tuebl, Textbook, Mobi or read online Mechanisms Of Cell Death And Opportunities For Therapeutic Development anytime and anywhere on any device. Get free access to the library by create an account, fast download and ads free. We cannot guarantee that every book is in the library.

Mechanisms of Cell Death and Opportunities for Therapeutic Development

Mechanisms of Cell Death and Opportunities for Therapeutic Development
  • Author : Diaqing Liao
  • Publisher :Unknown
  • Release Date :2019-08-15
  • Total pages :660
  • ISBN : 0128142081
GET BOOK HERE

Summary : This is the fourth volume in the Perspectives in Translational Cell Biology series, offering content for professors, students and researchers across basic and translational biology. Mechanisms of Cell Death and Opportunities for Therapeutic Development covers topics from fundamental mechanisms underlying different forms of cell death to drug development efforts for treating disease, providing a valuable resource for readers interested in understanding cell death and relevant translational research. Diaing Liao has over twenty years' experience teaching topics of cell death. He brings this experience to this work. Provides a comprehensive overview of current knowledge on the process of apoptosis, its potential role in health and disease, as well as a discussion of potential alternative forms of apoptosis such as autophagy Topics covered range from fundamental mechanisms to relevant translational research

Cell Death

Cell Death
  • Author : Tobias Ntuli
  • Publisher :Unknown
  • Release Date :2015-12-16
  • Total pages :446
  • ISBN : 9789535122364
GET BOOK HERE

Summary : This book is a collection of selected and relevant research, concerning the developments within the Cell Death field of study. Each contribution comes as a separate chapter complete in itself but directly related to the books topics and objectives. The target audience comprises scholars and specialists in the field.

Mechanisms of Cell Death

Mechanisms of Cell Death
  • Author : Cell Death Society
  • Publisher :Unknown
  • Release Date :1999
  • Total pages :213
  • ISBN : 1573312401
GET BOOK HERE

Summary : As the body of research on apoptosis grows, it paradoxically becomes simpler as the principles that define the field become more flexible and inclusive. Discussions of the role of cell death in AIDS, inflammatory disease, lung and cardiac disease, and lupus each emphasize the importance of understanding and regulating inflammation and the production of apoptotic bodies. Included in these proceedings is an in-depth review of the role of death cell genes, including intriguing studies of the existence of inhibitors of apoptosis in embryos. Many of these researchers now feel it is a combination, rather than any single gene, that activates apoptosis.

Cell Biology

Cell Biology
  • Author : Stevo Najman
  • Publisher :Unknown
  • Release Date :2016-01-20
  • Total pages :206
  • ISBN : 9789535122425
GET BOOK HERE

Summary : Cell biology is a multidisciplinary scientific field that its modern expansion in new knowledge and applications owes to important support of new technologies with the rapid development, such as ICTs. By integrating knowledge from nano-, molecular, micro-, and macroareas, it represents a strong foundation for almost all biological sciences and disciplines, as well as for biomedical research and application. This book is a compilation of inspiring reviews/original studies, which are divided into sections: New Methods in Cell Biology, Molecular and Cellular Regulatory Mechanisms, and Cellular Basis of Disease and Therapy. The book will be very useful for students and beginners to gain insight into new area, as well as for experts and scientists to find new facts and expand their scientific horizons through biological sciences and biomedicine.

Cell Death

Cell Death
  • Author : Douglas R. Green
  • Publisher :Unknown
  • Release Date :2018-09-30
  • Total pages :250
  • ISBN : 1621822141
GET BOOK HERE

Summary : One million cells in our bodies die every second--they commit suicide by a mechanism known as apoptosis. Apoptosis is essential for survival of the body as a whole and has critical roles in various developmental processes and the immune system. In Cell Death, Douglas Green provides a clear and comprehensive view of apoptosis and other cell death mechanisms. Taking a bottom-up approach, he starts with the enzymes that perform the execution process (a family of proteases termed caspases) and examines their cellular targets and the ways in which they are activated. He then looks at the molecular machinery that links signals that cause cell death to caspases, emphasizing the importance of the BCL-2 family of proteins and the role of cytochrome c released from mitochondria. The final stage of the process, phagocytic removal of dead or dying cells, is also covered. Green outlines the roles of apoptosis and death mechanisms such as necrosis in embryogenesis, neuronal selection, and the development of self-tolerance in the immune system. In addition, he explains how cell death defends the body against cancer and traces the evolutionary origins of the apoptosis machinery back over a billion years. This new edition contains critical new information on recent exciting advances in the field, such as new forms for cell death and important insights into the mechanisms and control of apoptosis. The book is thus of great use to all biologists interested in how cells function in the context of multicellular organisms and will appeal to everyone from undergraduates encountering the topic for the first time to researchers actively working in the field.

Autophagy in Health and Disease

Autophagy in Health and Disease
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2020-06-30
  • Total pages :444
  • ISBN : 9780128220221
GET BOOK HERE

Summary : Autophagy in Health and Disease, Volume 175, presents the latest insights from renowned experts in the field who discuss the key role of autophagic responses in the preservation of cellular and organismal homeostasis and how defects in the molecular apparatus for autophagy drive or accompany disease. Specific chapters in this new release include Crosstalk between autophagy and cell death signaling: mechanisms and therapeutic relevance, C. elegans to model autophagy-related human disorders, Autophagy in Kidney Disease: advances and therapeutic potential, Autophagy in Chronic Lung Disease, Autophagy in motoneuronal disorders, Strategies employed by viruses to manipulate autophagy, and much more. Provides an outstanding panel of recognized experts in the field who discuss the latest in autophagy Includes critical discussions of autophagy in the context of each major human disorder Models autophagy-related human pathologies in lower eukaryotes

Research Awards Index

Research Awards Index
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :1983
  • Total pages :229
  • ISBN : MINN:30000008789053
GET BOOK HERE

Summary :

Apoptosis in Health and Disease

Apoptosis in Health and Disease
  • Author : Robert R. Ruffolo Jr.,Frank Walsh
  • Publisher :Unknown
  • Release Date :2000-09-15
  • Total pages :368
  • ISBN : 9781135286668
GET BOOK HERE

Summary : The impact of Apoptosis, or programmed cell death, is thought to play a crucial role in the development and progression of disease. Whilst Apoptosis remains extensively studied in the context of immunology, the focus of research has greatly expanded to investigate the key role it is now believed to play in hematopoiesis, angiogenesis, inflammation

Biomedical Index to PHS-supported Research

Biomedical Index to PHS-supported Research
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :1990
  • Total pages :229
  • ISBN : IND:30000090515465
GET BOOK HERE

Summary :

Current Understanding of Apoptosis

Current Understanding of Apoptosis
  • Author : Yusuf Tutar,Lutfi Tutar
  • Publisher :Unknown
  • Release Date :2018-08-29
  • Total pages :160
  • ISBN : 9781789235005
GET BOOK HERE

Summary : Apoptosis is an essential biochemical process in cell turnover, development, and chemical-induced cell death. Current knowledge and ongoing research of apoptosis highlight our understanding in designing the therapeutic approaches for several diseases. This book covers four main sections: "Apoptosis and Necrosis," "Apoptosis Inducers," "Proteasome and Signaling Pathways in Apoptosis," and "Radiation-Based Apoptosis." The first section implicitly describes the differences between apoptosis and necrosis processes. The following section elaborates the small molecule-induced apoptosis. Then, the third section deals with proteasome and signaling pathways and finally, resistance to chemotherapy and electromagnetic radiation is covered in the last section. Overall, the book deals with pathways for manipulating apoptosis and provides a unique perspective to the scientists.

Cell Death

Cell Death
  • Author : Hao Wu
  • Publisher :Unknown
  • Release Date :2013-11-19
  • Total pages :272
  • ISBN : 9781461493020
GET BOOK HERE

Summary : Beginning from centuries of anecdotal descriptions of cell death, such as those on the development of the midwife toad in 1842 by Carl Vogt, to modern-day investigations of cell death as a biological discipline, it has become accepted that cell death in multicellular organisms is a normal part of life. This book provides a comprehensive view of cell death, from its mechanisms of initiation and execution, to its implication in human disease and therapy. Physiological cell death plays critical roles in almost all aspects of biology, and the book details its roles in lymphocyte homeostasis, neuronal function, metabolism, and the DNA damage response. When physiological cell death goes awry, diseases can arise, and cancer is presented as a central paradigm for the consequences of derangements in the interplay between cell survival and cell death. At the same time, the potential promise of targeted therapies aimed at interdicting cell death machineries are also discussed extensively. The molecular mechanisms that underlie apoptotic cell death are illustrated from the perspectives of both the intrinsic, mitochondrial apoptotic pathway and the extrinsic, death receptor pathway. Key players in these pathways, such as the Bcl2 family proteins, cytochrome c, Apaf-1, caspases, death receptor adapter proteins, and inhibitor of apoptosis proteins, are presented from both functional and structural angles. Until only a few years ago, programmed cell death has been considered essentially synonymous with apoptosis. However, we now know that programmed cell death can also take other forms such as necrosis or necroptosis, and to this end, the mechanisms that underlie programmed necrosis in development and host defense are illustrated. The past twenty plus years have seen an incredible growth of research in cell death, with one breakthrough after another, and the legacy still goes on with constant new surprises and findings. Long live cell death!

Signal Transduction and Communication in Cancer Cells

Signal Transduction and Communication in Cancer Cells
  • Author : H. Leon Bradlow,Luigi Castagnetta,Kurt Zaenker
  • Publisher :Unknown
  • Release Date :2004
  • Total pages :499
  • ISBN : STANFORD:36105119802010
GET BOOK HERE

Summary : In these proceedings for an October 2003 conference, contributors update topics and relevant issues in cancer research and clinical oncology, such as genetics, genomics, proteomics, signals and translational research in neuroectodermal timors, biomolecular surveying of cell signals, cell-to-cell communication, signals transduced by environmental and endogenous sex steroids, signals and molecular targets in human cancer tissues and cells, cell migration and adhesion, gene expression and silencing, and rational approaches to the design of therapeutics targeting molecular markers in hematologic malignancies. Topics of short papers include the induction of apoptosis and inhibition of cell growth in human hepatocellular carcinoma cells by COX-2 inhibitors and a report from a registry comparing rates of breast cancer in the city and province of Palermo. Annotation ©2005 Book News, Inc., Portland, OR (booknews.com).

Apoptosis, Cell Signaling, and Human Diseases

Apoptosis, Cell Signaling, and Human Diseases
  • Author : Rakesh Srivastava
  • Publisher :Unknown
  • Release Date :2007-11-05
  • Total pages :384
  • ISBN : 9781597452007
GET BOOK HERE

Summary : These volumes present a concise synthesis of recent developments in the understanding of both cell survival and apoptotic pathways. Particular attention is given to apoptosis in human diseases, such as different forms of cancer and neurodegenerative diseases. These comprehensive volumes integrate the most innovative and current findings from several related disciplines of scientific research, including pathology, genetics, virology, cell biology, immunology, and molecular biology.

Cancer Research

Cancer Research
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2006-02
  • Total pages :229
  • ISBN : CORNELL:31924101050072
GET BOOK HERE

Summary :

Colorectal Cancer

Colorectal Cancer
  • Author : Luis Rodrigo
  • Publisher :Unknown
  • Release Date :2016-09-07
  • Total pages :440
  • ISBN : 9789535125440
GET BOOK HERE

Summary : Colorectal cancer (CRC) is a major health problem because it represents around 10% of all cancers and achieves a worldwide estimate of 1.4 million newly diagnosed cases annually, resulting in approximately 700,000 deaths. Approximately 19-31% of patients present liver metastases. At diagnosis, a further 23-38% will develop extra-hepatic disease. Over the past decade, the widespread use of modern chemotherapeutic and biological agents, combined with laparoscopic surgical techniques, has improved the prognosis of metastatic CRC. A better understanding of the biology of the tumor, along with high efficiency of diagnostic and therapeutic methods, as well as the spread of screening programs, will improve the survival of the CRC patients in the near future.

Cell Death Signaling in Cancer Biology and Treatment

Cell Death Signaling in Cancer Biology and Treatment
  • Author : Daniel Johnson
  • Publisher :Unknown
  • Release Date :2012-11-19
  • Total pages :408
  • ISBN : 9781461458470
GET BOOK HERE

Summary : A key goal in the treatment of cancer is to achieve selective and efficient killing of tumor cells. The aim of Cell Death Signaling in Cancer Biology and Treatment is to describe state-of-the-art approaches and future opportunities for achieving this goal by targeting mechanisms and pathways that regulate cancer cell death. In this book, molecular defects in cell death signaling that characterize cancer cells, including dysregulation of cell death due to overexpression/hyperactivation of oncoproteins, as well as the loss of tumor suppressor proteins will be described. The potential for targeting microRNAs will be discussed. Multiple chapters will describe preclinical and clinical approaches that are currently being used to target epigenetic modifications, DNA repair pathways, and protein chaperones, as a means of provoking tumor cell death. Finally, the development and application of novel agents and approaches for targeting specific components of cell death signaling pathways and machinery will be reviewed.

New Insights into Theriogenology

New Insights into Theriogenology
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2018-12-05
  • Total pages :160
  • ISBN : 9781789847727
GET BOOK HERE

Summary : This book covers a variety of topics on animal reproduction and reproductive medicine. With evolving technology and a continual increase in knowledge, regarding domestic pets or agricultural animals, new information is available on diverse topics in this broad field. The book contents reflect the individual experience of authors, who developed a number of themes identified as attracting interest in the field. As it is, new opportunities were opened for productive collaboration. We have tried to provide you with current, specialised information that may be useful to students, clinicians and researchers. We hope this book inspires you to embrace these themes, foster the debate on particular topics and may be used as a start-up source for exploring the theriogenology field.

Mechanisms of Cell Death

Mechanisms of Cell Death
  • Author : Cell Death Society
  • Publisher :Unknown
  • Release Date :1999
  • Total pages :213
  • ISBN : STANFORD:36105024897386
GET BOOK HERE

Summary : Contains papers from a July 1998 conference held at the Queens College Campus of the City University of New York. Papers are arranged in sections on mechanisms and general considerations, programmed (developmental) cell death, and cell death and pathological and clinical situations. Specific topics

Apoptosis

Apoptosis
  • Author : Douglas R. Green
  • Publisher :Unknown
  • Release Date :2011-08-22
  • Total pages :229
  • ISBN : 9781139498739
GET BOOK HERE

Summary : Apoptosis, or cell death, can be pathological, a sign of disease and damage, or physiological, a process essential for normal health. This book, with contributions from experts in the field, provides a timely compilation of reviews of mechanisms of apoptosis. The book is organized into three convenient sections. The first section explores the different processes of cell death and how they relate to one another. The second section focuses on organ-specific apoptosis-related diseases. The third section explores cell death in non-mammalian organisms, such as plants. This comprehensive text is a must-read for all researchers and scholars interested in apoptosis.

Cell Death

Cell Death
  • Author : Csaba Szabo
  • Publisher :Unknown
  • Release Date :2000-06-22
  • Total pages :352
  • ISBN : 1420038893
GET BOOK HERE

Summary : Poly (ADP-ribose) polymerase (PARP), also termed poly (ADP-ribose) synthetase (PARS) is a nuclear enzyme with a wide range of functions, including regulation of DNA repair, cell differentiation, and gene expression. More than a decade after the identification of PARP-like enzymatic activities in mammalian cells, a novel role was proposed for this e

In Vivo

In Vivo
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2000
  • Total pages :229
  • ISBN : UCLA:L0090608001
GET BOOK HERE

Summary :