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Mechanisms of Morphogenesis

Mechanisms of Morphogenesis
  • Author : Jamie Davies
  • Publisher :Unknown
  • Release Date :2013-02-18
  • Total pages :414
  • ISBN : 9780124157576
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Summary : Morphogenesis is the set of processes that generate shape and form in the embryo--an important area within developmental biology. An exciting and up-to-the-minute account of the very latest research into the factors that create biological form, Mechanisms of Morphogenesis, second edition is a text reference on the mechanisms of cell and tissue morphogenesis in a diverse array of organisms, including prokaryotes, animals, plants and fungi. By combining hard data with computer modeling, Mechanisms of Morphogenesis, second edition equips readers with a much broader understanding of the scope of modern research than is otherwise available. The book focuses on the ways in which the genetic program is translated to generate cell shape, to direct cell migration, and to produce the shape, form and rates of growth of the various tissues. Each topic is illustrated with experimental data from real systems, with particular reference to gaps in current knowledge and pointers to future Includes over 200 four-color figures Offers an integrated view of theoretical developmental biology and computer modelling with laboratory-based discoveries Covers experimental techniques as a guide to the reader Organized around principles and mechanisms, using them to integrate discoveries from a range of organisms and systems

The Routledge Handbook of Mechanisms and Mechanical Philosophy

The Routledge Handbook of Mechanisms and Mechanical Philosophy
  • Author : Stuart Glennan,Phyllis Illari
  • Publisher :Unknown
  • Release Date :2017-07-06
  • Total pages :474
  • ISBN : 9781317552307
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Summary : Scientists studying the burning of stars, the evolution of species, DNA, the brain, the economy, and social change, all frequently describe their work as searching for mechanisms. Despite this fact, for much of the twentieth century philosophical discussions of the nature of mechanisms remained outside philosophy of science. The Routledge Handbook of Mechanisms and Mechanical Philosophy is an outstanding reference source to the key topics, problems, and debates in this exciting subject and is the first collection of its kind. Comprising over thirty chapters by a team of international contributors, the Handbook is divided into four Parts: Historical perspectives on mechanisms The nature of mechanisms Mechanisms and the philosophy of science Disciplinary perspectives on mechanisms. Within these Parts central topics and problems are examined, including the rise of mechanical philosophy in the seventeenth century; what mechanisms are made of and how they are organized; mechanisms and laws and regularities; how mechanisms are discovered and explained; dynamical systems theory; and disciplinary perspectives from physics, chemistry, biology, biomedicine, ecology, neuroscience, and the social sciences. Essential reading for students and researchers in philosophy of science, the Handbook will also be of interest to those in related fields, such as metaphysics, philosophy of psychology, and history of science.

Morphogenesis

Morphogenesis
  • Author : Jonathan B. L. Bard,Jonathan Bard
  • Publisher :Unknown
  • Release Date :1992-07-02
  • Total pages :328
  • ISBN : 0521436125
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Summary : This book, first published in 1990, provides an overview of the events and mechanisms of morphogenesis.

The Cellular Basis of Morphogenesis

The Cellular Basis of Morphogenesis
  • Author : Leon W. Browder
  • Publisher :Unknown
  • Release Date :2012-12-06
  • Total pages :668
  • ISBN : 9781461321415
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Summary : This series was established to create comprehensive treatises on specialized topics in developmental biology. Such volumes are especially vital in develop mental biology, since it is a very diverse field that receives contributions from a wide variety of disciplines. This series is a meeting-ground for the various practitioners of this science, facilitating an integration of heterogeneous infor mation on. specific topics. Each volume is intended to provide the conceptual basis for a comprehen sive understanding of its topic as well as an analysis of the key experiments upon which that understanding is based. The specialist in any aspect of devel opmental biology should understand the experimental background of the field and be able to place that body of information in context to ascertain where additional research would be fruitful. At that point, the creative process takes over, and new experiments are designed. This series is intended to be a vital link in that ongoing process of learning and discovery. If it facilitates schol arship, it will serve an important function.

Branching Morphogenesis

Branching Morphogenesis
  • Author : Jamie Davies
  • Publisher :Unknown
  • Release Date :2007-03-20
  • Total pages :246
  • ISBN : 9780387308739
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Summary : Branching morphogenesis, the creation of branched structures in the body, is a key feature of animal and plant development. This book brings together, for the first time, expert researchers working on a variety of branching systems to present a state-of-the-art view of the mechanisms that control branching morphogenesis. Systems considered range from single cells, to blood vessel and drainage duct systems to entire body plans, and approaches range from observation through experiment to detailed biophysical modelling. The result is an integrated overview of branching.

Constructional Morphology and Evolution

Constructional Morphology and Evolution
  • Author : Norbert Schmidt-Kittler,Klaus Vogel
  • Publisher :Unknown
  • Release Date :2012-12-06
  • Total pages :409
  • ISBN : 9783642761560
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Summary : Constructional morphology explains features of organisms from a constructional and functional point of view. By means of physical analysis it explains the operational aspects of organic structures - how they can perform the activities organisms are expected to fulfil in order to survive in their environment. Constructional morphology also explains options and constraints during the evolution determined by internal constructional needs, ontogenetic demands, inherited organizational preconditions and environmental clues.

Generative Mechanisms Transforming the Social Order

Generative Mechanisms Transforming the Social Order
  • Author : Margaret S. Archer
  • Publisher :Unknown
  • Release Date :2015-02-18
  • Total pages :248
  • ISBN : 9783319137735
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Summary : This volume examines how generative mechanisms emerge in the social order and their consequences. It does so in the light of finding answers to the general question posed in this book series: Will Late Modernity be replaced by a social formation that could be called Morphogenic Society? This volume clarifies what a ‘generative mechanism’ is, to achieve a better understanding of their social origins, and to delineate in what way such mechanisms exert effects within a current social formation, either stabilizing it or leading to changes potentially replacing it . The book explores questions about conjuncture, convergence and countervailing effects of morphogenetic mechanisms in order to assess their impact. Simultaneously, it looks at how products of positive feedback intertwine with the results of (morphostatic) negative feedback. This process also requires clarification, especially about the conditions under which morphostasis prevails over morphogenesis and vice versa. It raises the issue as to whether their co-existence can be other than short-lived. The volume addresses whether or not there also is a process of ‘morpho-necrosis’, i.e. the ultimate demise of certain morphostatic mechanisms, such that they cannot ‘recover’. The book concludes that not only are generative mechanisms required to explain associations between variables involved in the replacement of Late Modernity by Morphogenic Society, but they are also robust enough to account for cases and times when such variables show no significant correlations.

Molecular Biology of the Cell

Molecular Biology of the Cell
  • Author : Bruce Alberts
  • Publisher :Unknown
  • Release Date :2004
  • Total pages :229
  • ISBN : 0815332181
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Summary :

Social Morphogenesis

Social Morphogenesis
  • Author : Margaret S. Archer
  • Publisher :Unknown
  • Release Date :2013-02-20
  • Total pages :231
  • ISBN : 9789400761285
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Summary : The rate of social change has speeded up in the last three decades, but how do we explain this? This volume ventures what the generative mechanism is that produces such rapid change and discusses how this differs from late Modernity. Contributors examine if an intensification of morphogenesis (positive feedback that results in a change in social form) and a corresponding reduction in morphostasis (negative feedback that restores or reproduces the form of the social order) best captures the process involved. This volume resists proclaiming a new social formation as so many books written by empiricists have done by extrapolating from empirical data. Until we can convincingly demonstrate that a new generative mechanism is at work, it is premature to argue what accounts for the global changes that are taking place and where they will lead. More concisely we seek to answer the question whether or not current social change can be regarded as social morphogenesis. Only then, in the next volumes will the same team of authors be able to remove the question mark.

Organogenetic Gene Networks

Organogenetic Gene Networks
  • Author : James Castelli-Gair Hombría,Paola Bovolenta
  • Publisher :Unknown
  • Release Date :2016-08-26
  • Total pages :376
  • ISBN : 9783319427676
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Summary : All animals, including humans, derive from a single cell, which possesses all the genetic instructions needed to define how the animal will look like. However, during development, the millions of cells that derive from the zygote will only select part of this genetic information to give rise to the various organs of the body. The coordination of different cell behaviours during development results in the formation of specialized tissues and organs giving rise to highly adapted animals. This book provides an overview of how this diversification is achieved during organ formation and how it may have evolved. Conserved cellular processes are presented using examples from selected vertebrate and invertebrate species that illustrate how developmental biologists are solving the complex puzzle of organ formation. This volume is aimed to students, researchers and medical doctors alike who want to find a simple but rigorous introduction on how gene networks control organ formation.“div> /div

Morphogenesis of Endothelium

Morphogenesis of Endothelium
  • Author : Werner Risau,Gabor M. Rubanyi
  • Publisher :Unknown
  • Release Date :2003-09-02
  • Total pages :312
  • ISBN : 9780203304358
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Summary : The cardiovascular system is the first functional organ system to develop in the vertebrate embryo. Embryonic growth and differentiation essentially depend on transport of nutrients and waste through the early vasculature, and certain events in morphogenesis are thought to be influenced by the hemodynamic forces of the beating heart. The vasculature not only serves as a 'nutrient and waste pipeline' but is also a major communication system between distant organs and tissues. The vascular endothelial cell mediates vascular growth, permeability, integrity and interactions with blood cells. In most tissues the endothelium itself is highly specialized to meet the particular needs of the tissue in terms of quality and quantity of incoming and outgoing molecules and messages. The areas covered by Morphogenesis of the Endothelium include the formation of blood vessels in embryonic tissues by vasculogenesis and angiogenesis and the differentiation of endothelium in organs. The contributors are leaders in the field of cardiovascular development, biology and pathology and have written up to date chapters on the mechanisms of blood vessel formation and function in embryos and the adult.

Computer Models in Biomechanics

Computer Models in Biomechanics
  • Author : Gerhard A. Holzapfel,Ellen Kuhl
  • Publisher :Unknown
  • Release Date :2012-10-16
  • Total pages :416
  • ISBN : 9789400754645
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Summary : This book contains a collection of papers that were presented at the IUTAM Symposium on “Computer Models in Biomechanics: From Nano to Macro” held at Stanford University, California, USA, from August 29 to September 2, 2011. It contains state-of-the-art papers on: - Protein and Cell Mechanics: coarse-grained model for unfolded proteins, collagen-proteoglycan structural interactions in the cornea, simulations of cell behavior on substrates - Muscle Mechanics: modeling approaches for Ca2+–regulated smooth muscle contraction, smooth muscle modeling using continuum thermodynamical frameworks, cross-bridge model describing the mechanoenergetics of actomyosin interaction, multiscale skeletal muscle modeling - Cardiovascular Mechanics: multiscale modeling of arterial adaptations by incorporating molecular mechanisms, cardiovascular tissue damage, dissection properties of aortic aneurysms, intracranial aneurysms, electromechanics of the heart, hemodynamic alterations associated with arterial remodeling following aortic coarctation, patient-specific surgery planning for the Fontan procedure - Multiphasic Models: solutes in hydrated biological tissues, reformulation of mixture theory-based poroelasticity for interstitial tissue growth, tumor therapies of brain tissue, remodeling of microcirculation in liver lobes, reactions, mass transport and mechanics of tumor growth, water transport modeling in the brain, crack modeling of swelling porous media - Morphogenesis, Biological Tissues and Organs: mechanisms of brain morphogenesis, micromechanical modeling of anterior cruciate ligaments, mechanical characterization of the human liver, in vivo validation of predictive models for bone remodeling and mechanobiology, bridging scales in respiratory mechanics

Genetic Mechanisms of Development

Genetic Mechanisms of Development
  • Author : Frank H. Ruddle
  • Publisher :Unknown
  • Release Date :2013-09-17
  • Total pages :396
  • ISBN : 9781483261997
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Summary : Genetic Mechanisms of Development is a compilation of articles that surveys the application of genetic systems of analysis to the resolution of fundamental problems in developmental biology. The book is composed of sections that deal with various aspects of genetic mechanisms. The first section tackles the genetic analysis of gene regulation in microorganisms. The second section discusses the application of Mendelian genetics to the study of the development of Drosophila, amphibians, and the laboratory mouse. The last section introduces somatic cell genetics, a tool for developmental biologists. Biologists, geneticists, zoologists, and researchers will find the book a good source of information.

Heart Development

Heart Development
  • Author : Richard P. Harvey,Nadia Rosenthal
  • Publisher :Unknown
  • Release Date :1999
  • Total pages :530
  • ISBN : 0123298601
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Summary : This book examines recent studies revealing that the same genes are responsible for development of parallel features between species, and that the heart develops similarly across all species. It includes research being conducted concerning cardiac development, tissue interaction, and organ formation. The text attempts to provide a greater understanding of the underlying causes of heart failure, heart muscle diseases, congenital malformations, and other heart diseases and defects. Key Features * Each chapter has been solicited from a recognized leader in the field, and covers a topic of active research in cardiovascular biology * Chapters incorporate a review of classical findings with comprehensive coverage of the latest advances * Abundant color plates in a consistent and professional artistic style provide clear and attractive illustrations of central concepts * Color slides of illustrations for seminars or teaching purposes are available with each volume

Developmental Biology

Developmental Biology
  • Author : Michael Locke
  • Publisher :Unknown
  • Release Date :2014-05-12
  • Total pages :316
  • ISBN : 9781483263670
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Summary : Developmental Biology, Supplement 1: Control Mechanisms in Developmental Processes focuses on the process of how organs grow and develop. This book is organized into three main topics—role of cytoplasmic units, role of the nucleus, and regulatory mechanisms. This compilation specifically discusses the control mechanisms in plastid development, nuclear control of morphology, and possible involvement of mitochondrial DNA. The mode of operation of a regulatory system in maize, hooded gene in barley, and regulation of the cell cycle in mammalian cells are also described. This text likewise considers the development of immunocompetent cells, regulatory action of estrogenic hormones, and biological activity of uterine RNA. This publication is suitable for biologists, specialists, and students concerned with developmental processes.

Etiology and Morphogenesis of Congenital Heart Disease

Etiology and Morphogenesis of Congenital Heart Disease
  • Author : Toshio Nakanishi,Roger R. Markwald,H.Scott Baldwin,Bradley B. Keller,Deepak Srivastava,Hiroyuki Yamagishi
  • Publisher :Unknown
  • Release Date :2016-06-24
  • Total pages :383
  • ISBN : 9784431546283
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Summary : This volume focuses on the etiology and morphogenesis of congenital heart diseases. It reviews in detail the early development and differentiation of the heart, and later morphologic events of the cardiovascular system, covering a wide range of topics such as gene functions, growth factors, transcription factors and cellular interactions that are implicated in cardiac morphogenesis and congenital heart disease. This book also presents recent advances in stem cell and cell sheet tissue engineering technologies which have the potential to provide novel in vitro disease models and to generate regenerative paradigms for cardiac repair and regeneration. This is the ideal resource for physician scientists and investigators looking for updates on recent investigations on the origins of congenital heart disease and potential future therapies.

Cells and Biomaterials in Regenerative Medicine

Cells and Biomaterials in Regenerative Medicine
  • Author : Daniel Eberli
  • Publisher :Unknown
  • Release Date :2014-11-26
  • Total pages :384
  • ISBN : 9789535117315
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Summary : This book serves as a good starting point for anyone interested in the application of tissue engineering. It offers a colorful mix of topics, which explain the obstacles and possible solutions for TE applications. The first part covers the use of adult stem cells and their applications. The following chapters offer an insight into the development of a tailored biomaterial for organ replacement and highlight the importance of cell-biomaterial interaction. In summary, this book offers insights into a wide variety of cells, biomaterials, interfaces and applications of the next generation biotechnology, which is tissue engineering.

Mouse Development

Mouse Development
  • Author : Patrick T. Tam
  • Publisher :Unknown
  • Release Date :2002-03-15
  • Total pages :712
  • ISBN : 0125979517
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Summary : This book represents a classic compilation of current knowledge about mouse development and its correlates to research in cell biology, molecular biology, genetics, and neuroscience. Emphasis is placed on the research strategy, experimental design, and critical analysis of the data, disguishing this from other books that only focus on protocols for mouse developmental research. Selected chapters are indexed to electronic databases such as GeneBank, GenBank, Electronic Mouse Atlas, and Transgenic/Knockout, further increasing the utility of this book as a reference. *Broad-based overview of mouse development from fundamental to specialist levels *Extensive coverage of a wide range of developmental mutations of the mouse *Excellent benchmark illustrations of brain, craniofacial, gut and heart development *In-depth experiment-based assessment of concepts in mammalian development *Focus on models of specific relevance to human development *Comprehensive reference to key literature and electronic databases related to mouse development *High-quality full-color production

Advances in Morphogenesis

Advances in Morphogenesis
  • Author : M. Abercrombie,Jean Brachet,Thomas J. King
  • Publisher :Unknown
  • Release Date :2013-10-22
  • Total pages :336
  • ISBN : 9781483215617
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Summary : Advances in Morphogenesis, Volume 10, provides an overview of the state of knowledge in morphogenesis. The book contains six chapters and opens with a discussion of the "organization center" of the amphibian embryo. This is followed by separate chapters on physiological gradients in development; molecular embryology of the sea urchin, mollusks, and other invertebrates; and changes in DNA, RNA, and protein during successive phases of embryonic development in vertebrates. Subsequent chapters deal with the control of growth in the filamentous prothalli and the causal factors promoting the transition to the two-dimensional gametophyte; and the development, inheritance, and origin of the plastid in Euglena.

Morphogenesis and Maturation of Retroviruses

Morphogenesis and Maturation of Retroviruses
  • Author : Hans-Georg Kräusslich
  • Publisher :Unknown
  • Release Date :2012-12-06
  • Total pages :344
  • ISBN : 9783642801457
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Summary : Retroviruses arguably belong to the most fascinating of all viruses because of their unusual and highly efficient mode of replication involving reverse transcription and integration of the viral genome and a complex system of transcriptional and post transcriptional regulatory mechanisms. The importance of ret roviruses as human and animal pathogens has also enhanced scientific and medical interest in this diverse group of viruses and has spurred an intensive search for novel and improved antiviral agents. More recently, analysis of retroviral replication and in particular understanding the formation and composition of the virus particle has received additional attention because of the promise of retroviral vectors as vehicles for human somatic gene therapy. Many recent advances have been made in our understanding of the molecular mechanisms governing as sembly and release of infectious retrovirus particles. This book attempts to summarize these recent developments and to provide an overview of our current knowledge on retrovirus particle formation. The individual chapters of the book deal with specific steps in the pathway of retroviral morphogenesis and maturation, starting at the time when the components of the virus have been synthesized within the infected cell and ending once the infectious virion has been released from the cell. An introductory chapter provides a comparative description of the structure and morphology of various retroviruses.

Polyamines in Fungi

Polyamines in Fungi
  • Author : Laura Valdés-Santiago,José Ruiz-Herrera
  • Publisher :Unknown
  • Release Date :2015-11-18
  • Total pages :186
  • ISBN : 9781498717434
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Summary : It was not until recent years that the study of polyamines, their mechanisms of synthesis, and the roles they play in metabolism have flourished, becoming a fertile field of intense research. Polyamines in Fungi: Their Distribution, Metabolism, and Role in Cell Differentiation and Morphogenesis provides a complete overview of its topic. It is the first and only book to describe and analyze the roles of polyamines in fungi and compare them with the roles of polyamines in higher eukaryotes. The book contains data on the distribution of polyamines, their physiological functions, mechanism of synthesis and regulation, phylogenetic analyses of the enzymes involved in their synthesis, their use as possible targets for the control of fungal diseases, and possible biotechnological and medical applications. Based on work generated by the authors in their laboratory over many years, the book contains all the basic information to understand the similarities and differences of polyamine metabolism in eukaryotes. Additionally, it provides an up-to-date account of the contribution and potential use of fungi as models for the basic study of polyamines in comparison with other organisms.