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Modelling Degradation of Bioresorbable Polymeric Medical Devices

Modelling Degradation of Bioresorbable Polymeric Medical Devices
  • Author : J Pan
  • Publisher :Unknown
  • Release Date :2014-10-24
  • Total pages :260
  • ISBN : 1782420258
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Summary : The use of bioresorbable polymers in stents, fixation devices and tissue engineering is revolutionising medicine. Both industry and academic researchers are interested in using computer modelling to replace some experiments which are costly and time consuming. This book provides readers with a comprehensive review of modelling polymers and polymeric medical devices as an alternative to practical experiments. Chapters in part one provide readers with an overview of the fundamentals of biodegradation. Part two looks at a wide range of degradation theories for bioresorbable polymers and devices. The final set of chapters look at advances in modelling biodegradation of bioresorbable polymers. This book is an essential guide to those concerned with replacing tests and experiments with modelling. Provides a comprehensive mathematical framework for computer modelling of polymers and polymeric medical devices that can significantly reduce the number of experiments needed. Reviews the fundamental methods of modelling degradation, and applies these to particular materials including amorphous bioresorbable polyesters, semicrystalline biodegradable polyesters, and composite materials made of biodegradable polyesters and triclcium phosphates

Science and Principles of Biodegradable and Bioresorbable Medical Polymers

Science and Principles of Biodegradable and Bioresorbable Medical Polymers
  • Author : Xiang Cheng Zhang
  • Publisher :Unknown
  • Release Date :2016-09-22
  • Total pages :476
  • ISBN : 0081003935
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Summary : Science and Principles of Biodegradable and Bioresorbable Medical Polymers: Materials and Properties provides a practical guide to the use of biodegradable and bioresorbable polymers for study, research, and applications within medicine. Fundamentals of the basic principles and science behind the use of biodegradable polymers in advanced research and in medical and pharmaceutical applications are presented, as are important new concepts and principles covering materials, properties, and computer modeling, providing the reader with useful tools that will aid their own research, product design, and development. Supported by practical application examples, the scope and contents of the book provide researchers with an important reference and knowledge-based educational and training aid on the basics and fundamentals of these important medical polymers. Provides a practical guide to the fundamentals, synthesis, and processing of bioresorbable polymers in medicine Contains comprehensive coverage of material properties, including unique insights into modeling degradation Written by an eclectic mix of international authors with experience in academia and industry

A Phenomenological Mathematical Modelling Framework for the Degradation of Bioresorbable Composites

A Phenomenological Mathematical Modelling Framework for the Degradation of Bioresorbable Composites
  • Author : Ismael Moreno-Gomez
  • Publisher :Unknown
  • Release Date :2019-04-05
  • Total pages :325
  • ISBN : 3030049906
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Summary : This book presents a generalised computational model for the degradation of resorbable composites, using analytic expressions to represent the interwoven phenomena present during degradation. It then combines this modelling framework with a comprehensive database of quantitative degradation data mined from existing literature and from novel experiments, to provide new insights into the interrelated factors controlling degradation. Resorbable composites made of biodegradable polyesters and calcium-based ceramics have significant therapeutic potential as tissue engineering scaffolds, as temporary implants and as drug-loaded matrices for controlled release. However, their degradation is complex and the rate of resorption depends on multiple connected factors such as the shape and size of the device, polymer chemistry and molecular weight, particle phase, size, volume fraction, distribution and pH-dependent dissolution properties. Understanding and ultimately predicting the degradation of resorbable composites is of central importance if we are to fully unlock the promise of these materials.

Bioresorbable Polymers for Biomedical Applications

Bioresorbable Polymers for Biomedical Applications
  • Author : Giuseppe Perale,Jöns Hilborn
  • Publisher :Unknown
  • Release Date :2016-08-24
  • Total pages :628
  • ISBN : 0081002661
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Summary : Bioresorbable Polymers for Biomedical Applications: From Fundamentals to Translational Medicine provides readers with an overview of bioresorbable polymeric materials in the biomedical field. A useful resource for materials scientists in industry and academia, offering information on the fundamentals and considerations, synthesis and processing, and the clinical and R and D applications of bioresorbable polymers for biomedical applications. Focuses on biomedical applications of bioresorbable polymers Features a comprehensive range of topics including fundamentals, synthesis, processing, and applications Provides balanced coverage of the field with contributions from academia and industry Includes clinical and R and D applications of bioresorbable polymers for biomedical applications

Medical Modelling

Medical Modelling
  • Author : Richard Bibb,Dominic Eggbeer,Abby Paterson
  • Publisher :Unknown
  • Release Date :2014-12-13
  • Total pages :516
  • ISBN : 1782423133
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Summary : Medical modelling and the principles of medical imaging, Computer Aided Design (CAD) and Rapid Prototyping (also known as Additive Manufacturing and 3D Printing) are important techniques relating to various disciplines - from biomaterials engineering to surgery. Building on the success of the first edition, Medical Modelling: The application of Advanced Design and Rapid Prototyping techniques in medicine provides readers with a revised edition of the original text, along with key information on innovative imaging techniques, Rapid Prototyping technologies and case studies. Following an overview of medical imaging for Rapid Prototyping, the book goes on to discuss working with medical scan data and techniques for Rapid Prototyping. In this second edition there is an extensive section of peer-reviewed case studies, describing the practical applications of advanced design technologies in surgical, prosthetic, orthotic, dental and research applications. Covers the steps towards rapid prototyping, from conception (modelling) to manufacture (manufacture) Includes a comprehensive case studies section on the practical application of computer-aided design (CAD) and rapid prototyping (RP) Provides an insight into medical imaging for rapid prototyping and working with medical scan data

Handbook of Biodegradable Polymers

Handbook of Biodegradable Polymers
  • Author : Abraham J. Domb,Joseph Kost,David Wiseman
  • Publisher :Unknown
  • Release Date :1998-02-04
  • Total pages :544
  • ISBN : 9781420049367
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Summary : Handbook of Biodegradable Polymers, the seventh volume in the Drug Delivery and Targeting book series, provides a source manual for synthetic procedures, properties and applications of bioerodible polymers. The authors describe widely available materials such as polyactides, collagen and gelatin, as well as polymers of emerging importance, such as the genetically-engineered and elastin-based polymers which are either proprietary or in early stages of development. Section I addresses synthetic absorbable polymers, and Section 2 profiles natural, semi-synthetic and biosynthetic polymers. Section 3 discusses the surface characterization of degradable polymers, the modeling of biodegradation and non-medical polymers. This book is ideal for researchers from academia and industry as well as chemists, pharmacists and physicians who deal with biopolymers, drug delivery and targeting, bioengineering and implantable devices.

Biodegradation

Biodegradation
  • Author : Rolando Chamy
  • Publisher :Unknown
  • Release Date :2013-06-14
  • Total pages :380
  • ISBN : 953511154X
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Summary : This book contains a collection of different biodegradation research activities where biological processes take place. The book has two main sections: A) Polymers and Surfactants Biodegradation and B) Biodegradation: Microbial Behaviour.

Degradation Rate of Bioresorbable Materials

Degradation Rate of Bioresorbable Materials
  • Author : F J Buchanan
  • Publisher :Unknown
  • Release Date :2008-09-26
  • Total pages :424
  • ISBN : 1845695038
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Summary : Bioresorbable materials are extensively used for a wide range of biomedical applications from drug delivery to fracture fixation, and may remain in the body for weeks, months or even years. Accurately predicting and evaluating the degradation rate of these materials is critical to their performance and the controlled release of bioactive agents. Degradation rate of bioresorbable materials provides a comprehensive review of the most important techniques in safely predicting and evaluating the degradation rate of polymer, ceramic and composite based biomaterials. Part one provides an introductory review of bioresorbable materials and the biological environment of the body. Chapters in Part two address degradation mechanisms of commonly used materials such as polymers and ceramics. This is followed by chapters on bioresorption test methods and modelling techniques in Part three. Part four discusses factors influencing bioresorbability such as sterilisation, porosity and host response. The final section reviews current clinical applications of bioresorbable materials. With its distinguished editor and multidisciplinary team of international contributors, Degradation rate of bioresorbable materials: prediction and evaluation provides a unique and valuable reference for biomaterials scientists, engineers and students as well as the medical community. Comprehensively reviews the most pertinent techniques in safely predicting and evaluating the degradation rate of bioresorbable materials Addresses degradation mechanisms of commonly used materials Discusses factors influencing bioresorbability such as sterilisation and host response

Modeling of Biological Materials

Modeling of Biological Materials
  • Author : Francesco Mollica,Luigi Preziosi,K. R. Rajagopal
  • Publisher :Unknown
  • Release Date :2007-12-31
  • Total pages :358
  • ISBN : 9780817644116
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Summary : This unique collection highlights the central role played by modeling in general, and the modeling of mechanical considerations that have an effect on living matter. The volume collects several survey papers by actively working specialists, dealing with some of the most important problems – both theoretical and practical – in biomechanics. Written in a user-friendly style, these papers clearly explain both the biomedical and mechanical backgrounds associated with complex phenomena. This book may be used in interdisciplinary introductory courses covering various biomechanical topics for graduate students in applied mathematics, engineering, and biomedicine.

Biomaterials and Medical Devices

Biomaterials and Medical Devices
  • Author : Ferdyansyah Mahyudin,Hendra Hermawan
  • Publisher :Unknown
  • Release Date :2016-03-29
  • Total pages :242
  • ISBN : 3319148451
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Summary : This book presents an introduction to biomaterials with the focus on the current development and future direction of biomaterials and medical devices research and development in Indonesia. It is the first biomaterials book written by selected academic and clinical experts experts on biomaterials and medical devices from various institutions and industries in Indonesia. It serves as a reference source for researchers starting new projects, for companies developing and marketing products and for governments setting new policies. Chapter one covers the fundamentals of biomaterials, types of biomaterials, their structures and properties and the relationship between them. Chapter two discusses unconventional processing of biomaterials including nano-hybrid organic-inorganic biomaterials. Chapter three addresses biocompatibility issues including in vitro cytotoxicity, genotoxicity, in vitro cell models, biocompatibility data and its related failure. Chapter four describes degradable biomaterial for medical implants, which include biodegradable polymers, biodegradable metals, degradation assessment techniques and future directions. Chapter five focuses on animal models for biomaterial research, ethics, care and use, implantation study and monitoring and studies on medical implants in animals in Indonesia. Chapter six covers biomimetic bioceramics, natural-based biocomposites and the latest research on natural-based biomaterials in Indonesia. Chapter seven describes recent advances in natural biomaterial from human and animal tissue, its processing and applications. Chapter eight discusses orthopedic applications of biomaterials focusing on most common problems in Indonesia, and surgical intervention and implants. Chapter nine describes biomaterials in dentistry and their development in Indonesia.

Principles of Polymerization

Principles of Polymerization
  • Author : George Odian
  • Publisher :Unknown
  • Release Date :2004-02-09
  • Total pages :848
  • ISBN : 0471274003
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Summary : The new edition of a classic text and reference The large chains of molecules known as polymers are currently used in everything from "wash and wear" clothing to rubber tires to protective enamels and paints. Yet the practical applications of polymers are only increasing; innovations in polymer chemistry constantly bring both improved and entirely new uses for polymers onto the technological playing field. Principles of Polymerization, Fourth Edition presents the classic text on polymer synthesis, fully updated to reflect today's state of the art. New and expanded coverage in the Fourth Edition includes: * Metallocene and post-metallocene polymerization catalysts * Living polymerizations (radical, cationic, anionic) * Dendrimer, hyperbranched, brush, and other polymer architectures and assemblies * Graft and block copolymers * High-temperature polymers * Inorganic and organometallic polymers * Conducting polymers * Ring-opening polymer ization * In vivo and in vitro polymerization Appropriate for both novice and advanced students as well as professionals, this comprehensive yet accessible resource enables the reader to achieve an advanced, up-to-date understanding of polymer synthesis. Different methods of polymerization, reaction parameters for synthesis, molecular weight, branching and crosslinking, and the chemical and physical structure of polymers all receive ample coverage. A thorough discussion at the elementary level prefaces each topic, with a more advanced treatment following. Yet the language throughout remains straightforward and geared towards the student. Extensively updated, Principles of Polymerization, Fourth Edition provides an excellent textbook for today's students of polymer chemistry, chemical engineering, and materials science, as well as a current reference for the researcher or other practitioner working in these areas.

Biodegradable Systems in Tissue Engineering and Regenerative Medicine

Biodegradable Systems in Tissue Engineering and Regenerative Medicine
  • Author : Rui L. Reis,Julio San Román
  • Publisher :Unknown
  • Release Date :2004-11-29
  • Total pages :592
  • ISBN : 1135494428
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Summary : Conventional materials technology has yielded clear improvements in regenerative medicine. Ideally, however, a replacement material should mimic the living tissue mechanically, chemically, biologically and functionally. The use of tissue-engineered products based on novel biodegradable polymeric systems will lead to dramatic improvements in health

Biopolymers: Applications and Trends

Biopolymers: Applications and Trends
  • Author : Michael Niaounakis
  • Publisher :Unknown
  • Release Date :2015-08-13
  • Total pages :604
  • ISBN : 0323354335
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Summary : Biopolymers: Applications and Trends provides an up-to-date summary of the varying market applications of biopolymers characterized by biodegradability and sustainability. It includes tables with the commercial names and properties of each biopolymer family, along with biopolymers for each marketing segment, not only presenting all the major market players, but also highlighting trends and new developments in products. The book includes a thorough breakdown of the vast range of application areas, including medical and pharmaceutical, packaging, construction, automotive, and many more, giving engineers critical materials information in an area which has traditionally been more limited than conventional polymers. In addition, the book uses recent patent information to convey the latest applications and techniques in the area, thus further illustrating the rapid pace of development and need for intellectual property for companies working on new and innovative products. Provides an up-to-date summary of the varying market applications of biopolymers characterized by biodegradability and sustainability Includes tables with the commercial names and properties of each biopolymer family, along with biopolymers for each marketing segment Presents a thorough breakdown of the vast range of application areas, including medical and pharmaceutical, packaging, construction, automotive, and many more Uses recent patent information to convey the latest applications and techniques in the area, thus further illustrating the rapid pace of development and need for intellectual property

The Biomaterials: Silver Jubilee Compendium

The Biomaterials: Silver Jubilee Compendium
  • Author : David F. Williams
  • Publisher :Unknown
  • Release Date :2011-07-28
  • Total pages :256
  • ISBN : 9780080528069
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Summary : The journal Biomaterials was launched in 1980. The subject of biomaterials science was then in its infancy, being largely cofined to the study of the characteristics of materials used for medical devices. Twenty-five years on, we can truly say that biomaterials science has matured at an incredible rate and now represents a formidable sector that bridges the materials sciences, advanced medical therapies, and molecular and cell sciences. This Silver Jubilee Compendium consists of reprinted versions of the top 25 papers, published during these 25 years, as judged by an international panel of biomaterials scientists. This book is published as a landmark in biomaterials science and it is to be hoped that it will serve as a stimulus to young biomaterials scientists of the early twenty-first century for their pioneering work of the future.

Biomaterials Science

Biomaterials Science
  • Author : Buddy D. Ratner,Allan S. Hoffman,Frederick J. Schoen,Jack E. Lemons
  • Publisher :Unknown
  • Release Date :2004-08-18
  • Total pages :864
  • ISBN : 008047036X
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Summary : The second edition of this bestselling title provides the most up-to-date comprehensive review of all aspects of biomaterials science by providing a balanced, insightful approach to learning biomaterials. This reference integrates a historical perspective of materials engineering principles with biological interactions of biomaterials. Also provided within are regulatory and ethical issues in addition to future directions of the field, and a state-of-the-art update of medical and biotechnological applications. All aspects of biomaterials science are thoroughly addressed, from tissue engineering to cochlear prostheses and drug delivery systems. Over 80 contributors from academia, government and industry detail the principles of cell biology, immunology, and pathology. Focus within pertains to the clinical uses of biomaterials as components in implants, devices, and artificial organs. This reference also touches upon their uses in biotechnology as well as the characterization of the physical, chemical, biochemical and surface properties of these materials. Provides comprehensive coverage of principles and applications of all classes of biomaterials Integrates concepts of biomaterials science and biological interactions with clinical science and societal issues including law, regulation, and ethics Discusses successes and failures of biomaterials applications in clinical medicine and the future directions of the field Cover the broad spectrum of biomaterial compositions including polymers, metals, ceramics, glasses, carbons, natural materials, and composites Endorsed by the Society for Biomaterials

Integrated Biomaterials Science

Integrated Biomaterials Science
  • Author : Rolando Barbucci
  • Publisher :Unknown
  • Release Date :2007-05-08
  • Total pages :1037
  • ISBN : 0306475839
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Summary : Integrated Biomaterials Science provides an intriguing insight into the world of biomaterials. It explores the materials and technology which have brought advances in new biomaterials, highlighting the way in which modern biology and medicine are synergistically linked to other key scientific disciplines-physics, chemistry, and engineering. In doing so, Integrated Biomaterials Science contains chapters on tissue engineering and gene therapy, standards and parameters of biomaterials, applications and interactions within the industrial world, as well as potential aspects of patent regulations. Integrated Biomaterials Science serves as a comprehensive guide to understanding this dynamic field, yet is designed so that chapters may be read and understood independently, depending on the needs of the reader. Integrated Biomaterials Science is attractive to a broad audience interested in a deeper understanding of this evolving field, and serves as a key resource for researchers and students of biomaterials courses, providing all with an opportunity to probe further.

Biodegradable Polymers

Biodegradable Polymers
  • Author : Reza Arshady
  • Publisher :Unknown
  • Release Date :2003
  • Total pages :396
  • ISBN : 09876543XX
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Summary :

Handbook of Biodegradable Polymers

Handbook of Biodegradable Polymers
  • Author : Catia Bastioli
  • Publisher :Unknown
  • Release Date :2020-03-09
  • Total pages :572
  • ISBN : 150151198X
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Summary : This handbook covers characteristics, processability and application areas of biodegradable polymers, with key polymer family groups discussed. It explores the role of biodegradable polymers in different waste management practices including anaerobic digestion, and considers topics such as the different types of biorefineries for renewable monomers used in producing the building blocks for biodegradable polymers.

Biodegradable Polymers in Clinical Use and Clinical Development

Biodegradable Polymers in Clinical Use and Clinical Development
  • Author : Abraham J. Domb,Neeraj Kumar
  • Publisher :Unknown
  • Release Date :2011-05-12
  • Total pages :752
  • ISBN : 9781118015803
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Summary : This book focuses on biodegradable polymers that are already in clinical use or under clinical development. Synthetic and natural polymers will be included. This excludes polymers that have been investigated and did not reach clinical development. The purpose of this book is to provide updated status of the polymers that are clinical use and those that are now being developed for clinical use and hopefully will reach the clinic during the next 5 years. The book provides information that of interest to academics and practicing researchers including chemists, biologists and bioengineers and users: physicians, pharmacists.

Encyclopedia of Biomaterials and Biomedical Engineering

Encyclopedia of Biomaterials and Biomedical Engineering
  • Author : Gary E. Wnek,Gary L. Bowlin
  • Publisher :Unknown
  • Release Date :2008-05-28
  • Total pages :3552
  • ISBN : 1498761437
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Summary : Written by more than 400 subject experts representing diverse academic and applied domains, this multidisciplinary resource surveys the vanguard of biomaterials and biomedical engineering technologies utilizing biomaterials that lead to quality-of-life improvements. Building on traditional engineering principles, it serves to bridge advances in mat

Degradable Polymers

Degradable Polymers
  • Author : G. Scott,D. Gilead
  • Publisher :Unknown
  • Release Date :2012-12-06
  • Total pages :271
  • ISBN : 9401105715
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Summary : Few scientific developments in recent years have captured the popular imagination like the subject of'biodegradable' plastics. The reasons for this are complex and lie deep in the human subconscious. Discarded plastics are an intrusion on the sea shore and in the countryside. The fact that nature's litter abounds in the sea and on land is acceptable because it is biodegradable - even though it may take many years to be bioassimilated into the ecosystem. Plastics litter is not seen to be biodegradable and is aesthetically unacceptable because it does not blend into the natural environment. To the environmentally aware but often scientifically naive, biodegradation is seen to be the ecologically acceptable solution to the problem of plastic packaging waste and litter and some packaging manufacturers have exploited the 'green' consumer with exaggerated claims to 'environmentally friendly' biodegradable packaging materials. The principles underlying environmental degradation are not understood even by some manufacturers of 'biodegradable' materials and the claims made for them have been categorized as 'deceptive' by USA legislative authorities. This has set back the acceptance of plastics with controlled biodegradability as part of the overall waste and litter control strategy. At the opposite end of the commercial spectrum, the polymer manufactur ing industries, through their trade associations, have been at pains to discount the role of degradable materials in waste and litter management. This negative campaign has concentrated on the supposed incompatibility of degradable plastics with aspects of waste management strategy, notably materials recycling.