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Motor Neuron Disorders

Motor Neuron Disorders
  • Author : Pamela J. Shaw,Michael J. Strong
  • Publisher :Unknown
  • Release Date :2003
  • Total pages :569
  • ISBN : UOM:39015060031468
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Summary : This book includes state-of-the-art discussions of the pathogenesis of amyotrophic lateral sclerosis; new information on the genetic basis and clinical management of spinal muscular atrophy; current understanding of Kennedy's disease; and recent findings on hereditary spastic paraparesis. This book will deliver the guidance the reader needs to accurately diagnose any type of motor neuron disorder and manage it using effective methods.

Motor Neuron Disorders and Related Diseases

Motor Neuron Disorders and Related Diseases
  • Author : Andrew Eisen,Pamela J. Shaw, MD
  • Publisher :Unknown
  • Release Date :2007-01-19
  • Total pages :464
  • ISBN : 0444518940
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Summary : This volume provides a comprehensive and scholarly accounting of motor neuron disorders, a group of diseases that are both clinically and genetically diverse. Clinicians and neuroscientists alike will find invaluable research and information on recent advancements that have occurred in the understanding of these disorders. From specific discussions of their underlying molecular pathogenesis, to advancements in therapies and diagnosis, users will find a resource that presents a comprehensive understanding of the general clinical features and management of these devastating disorders. In addition, new tactics that can be used to enhance patient care are also presented and discussed. Specific chapters within the volume include discussions pertaining to the historical aspects of motor neuron diseases, comparative anatomy, physiology, and development of the corticospinal system, and discussions of spinal muscular atrophies, amongst others. In addition, symptomatic therapy and the palliative aspects of clinical patient care are also presented. * A scholarly accounting of new research in motor neuron disorders and their associated diseases * The intricate relationships that exist between different motor neuron related disorders * A comprehensive resource that provides a guide to the diagnosis and treatment of motor neuron disorders, along with new approaches to patient care

Motor Neuron Disease

Motor Neuron Disease
  • Author : Kevin Talbot,Rachael Marsden,Rachel Botell
  • Publisher :Unknown
  • Release Date :2010
  • Total pages :214
  • ISBN : 9780199547364
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Summary : Written and designed to provide comprehensive, easily accessible advice for all healthcare professionals involved in the care of patients with this challenging condition, this book addresses the entire care pathway from presentation to diagnosis to symptom management and end of life issues.

Motor Neuron Disease in Adults

Motor Neuron Disease in Adults
  • Author : Mark Bromberg
  • Publisher :Unknown
  • Release Date :2014-10-02
  • Total pages :352
  • ISBN : 9780199783168
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Summary : Motor Neuron Disease in Adults reviews new information as it applies to all aspects of motor neuron disease (ALS, PLS, PMA). The choice of articles is for those that use evidence-based methods to ensure that the new information is solid and advances the topic or issue. The book can be used by anyone who provides any type of care to ALS patients. In particular, neurologists will find the latest information on diagnosis and management, as well as new information on genetics and frontotemporal lobe involvement. Allied health providers will find useful information for their discipline. Patients will also find both specific and general information to help understand what they are experiencing and how to help manage their symptoms.

Molecular and Cellular Therapies for Motor Neuron Diseases

Molecular and Cellular Therapies for Motor Neuron Diseases
  • Author : Nicholas M Boulis,Deirdre O’Connor,Anthony Donsante
  • Publisher :Unknown
  • Release Date :2017-01-18
  • Total pages :336
  • ISBN : 9780128025246
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Summary : Molecular and Cellular Therapies for Motor Neuron Diseases discusses the basics of the diseases, also covering advances in research and clinical trials. The book provides a resource for students that will help them learn the basics in a detailed manner that is required for scientists and clinicians. Users will find a comprehensive overview of the background of Amyotrophic Lateral Sclerosis (ALS/Lou Gehrig’s Disease) and Spinal Muscular Atrophy (SMA), along with the current understanding of their genetics and mechanisms. In addition, the book details gene and cell therapies that have been developed and their translation to clinical trials. Provides an overview of gene and cell therapies for amyotrophic lateral sclerosis (ALS) and other motor neuron diseases Edited by a leading Neurosurgeon and two research scientists to promote synthesis between basic neuroscience and clinical relevance Presents a great resource for researchers and practitioners in neuroscience, neurology, and gene and cell therapy

Motor Neuron Diseases

Motor Neuron Diseases
  • Author : Bradley J. Turner
  • Publisher :Unknown
  • Release Date :2014-01-01
  • Total pages :244
  • ISBN : 1631173421
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Summary : Motor neuron disease (MND), also commonly known as amyotrophic lateral sclerosis (ALS), is a chronic neurodegenerative disorder of the motor system in adults, characterized by the loss of motor neurons in the cortex, brain stem and spinal cord. This book presents current research from across the globe in the study of the causes, classification and treatments of MND, including membrane trafficking defects as determinants of motor neuron susceptibility and degeneration in ALS; motorneuron specific calcium dysregulation and perturbed cellular calcium homeostasis in ALS; stem cells and their application in ALS treatment; excitotoxicity and selective motor neuron degeneration and therapeutic invervention and assistive technology treatments. (Imprint: Nova Biomedical)

Neurodegeneration

Neurodegeneration
  • Author : Ted M. Dawson
  • Publisher :Unknown
  • Release Date :2017-04-24
  • Total pages :344
  • ISBN : 9780470672686
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Summary : This book unites the diverse range of complex neurodegenerative diseases into a textbook designed for clinical practice, edited by globally leading authorities on the subject. Presents a clinically oriented guide to the diseases caused by neurodegeneration Templated chapters combine clinical and research information on neurodegenerative diseases beginning with the common elements before treating each disease individually Diseases are grouped by anatomical regions of degeneration and include common disorders such as Parkinson’s Disease, Alzheimer’s Disease, Amyotrophic Lateral Sclerosis/Motor Neuron Disease, and Multiple Sclerosis as well as less common diseases Edited by globally leading authorities on the subject, and written by expert contributing authors

Clinical and Molecular Aspects of Motor Neuron Disease

Clinical and Molecular Aspects of Motor Neuron Disease
  • Author : Johnathan Cooper-Knock,Thomas Jenkins,Pamela J. Shaw
  • Publisher :Unknown
  • Release Date :2013-09-01
  • Total pages :60
  • ISBN : 9781615044290
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Summary : In this e-book, motor neuron disease (MND) shall refer to amyotrophic lateral sclerosis (ALS), the most common neurodegenerative disorder affecting both the upper and lower motor neurons. With the discovery of C9ORF72 expansions in approximately 10% of all MND cases, in certain populations, we stand at the brink of a new era of MND research and hopefully treatment facilitated by the ability to associate a relatively large group of patients with a similar disease mechanism. This review will summarise both current clinical management of MND and our present understanding of the molecular pathogenesis of MND. Study of C9ORF72-MND has the potential to rapidly advance both of these aspects in the coming years.

Current Advances in Amyotrophic Lateral Sclerosis

Current Advances in Amyotrophic Lateral Sclerosis
  • Author : Alvaro Estévez
  • Publisher :Unknown
  • Release Date :2013-09-11
  • Total pages :266
  • ISBN : 9789535111955
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Summary : Our understanding of the pathology of amyotrophic lateral sclerosis is a continuously changing field. New hypotheses are generated with each new discovery; they are abandoned to be reanalyzed after some time under the light of new observations. This book present a series of reviews from experts in different aspects of the disease focus on these hypotheses. There are also a few review chapters providing clear examples of these new observations that make the field to reanalyze previous conclusions.

McLean EMG Guide, Second Edition

McLean EMG Guide, Second Edition
  • Author : Christopher J. Visco, MD
  • Publisher :Unknown
  • Release Date :2019-04-10
  • Total pages :280
  • ISBN : 9780826172136
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Summary : Revised, updated, and expanded second edition of the premier learning guide for residents, McLean EMG Guide emphasizes skills and concepts required for success in mastering basic electrodiagnostic techniques. This step-by-step approach to performing and interpreting EMG and nerve conduction studies will prepare trainees, fellows, and attendings to meet the challenges encountered in daily practice with confidence. The book is broken into short formatted chapters covering instrumentation, basic nerve conduction and needle EMG techniques, interpretation, applications for common clinical problems, and a new chapter on ultrasound. The procedures are laid out as illustrated tables with specifics for lead placement, stimulation, sample waveforms, and photographs to guide electrodiagnostic set-ups. Clinical presentation, anatomy, recommended studies, normal values, pearls and tips, and key findings are presented throughout in bulleted text for a thorough, more focused guidebook. Multiple choice questions and answers with rationales reinforce learning for those wishing to review concepts through self-guided assessment. Key Features Updates to all chapters with new figures and diagrams and more multiple-choice questions with answers Brand new chapter on the use of ultrasound with electrodiagnosis Checklists with key steps and takeaways for each study Clear, easy-to-understand tables and photos illustrate each set-up and study Codifies what you need to know to make a diagnosis in the EMG laboratory Print purchase includes on-line access to the full contents for mobile or desktop use

Practical Guide to Neurogenetics E-Book

Practical Guide to Neurogenetics E-Book
  • Author : Thomas T. Warner,Simon R. Hammans
  • Publisher :Unknown
  • Release Date :2008-11-04
  • Total pages :344
  • ISBN : 9780702038457
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Summary : This simple guide to neurogenetics demystifies the overwhelming amount of information on the subject so you can identify key clinical features and understand your management options. Reach relevant differential diagnoses and provide appropriate counseling to your patients using the symptom-based approach. By integrating genetic and neurological approaches to diagnoses, this book ensures that the neurological consequences of a genetic diagnosis and the genetic consequences of a neurological diagnosis are clear and explicit. Concise and portable, this book is ideal for easy reference in clinical use. Details the underlying basic science and clinical features of genetic disorders by taking a symptom-based approach to provide you with a comprehensive understanding of the field. Focuses on the clinical application of neurogenetics to be of practical use to you in the clinic. Clarifies the neurological consequences of a genetic diagnosis and the genetic consequences of a neurological diagnosis by integrating genetic and neurological approaches to diagnoses. Discusses and evaluates necessary investigations so you know when to use them and when to refer. Highlights diagnostic and therapeutic tips so you can learn new concepts or refine your skills in practice. Refers to online sources, such as Online Mendelian Inheritance in Man (OMIM) and others, to help you supplement your knowledge.

Update on Amyotrophic Lateral Sclerosis

Update on Amyotrophic Lateral Sclerosis
  • Author : Humberto Foyaca Sibat,Lourdes de Fátima Ibañez-Valdés
  • Publisher :Unknown
  • Release Date :2016-09-14
  • Total pages :280
  • ISBN : 9789535126003
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Summary : This book contains selected peer-reviewed chapters which cover updated information on ALS written by international researchers. Update on Amyotrophic Lateral Sclerosis is comprised of 13 chapters from some of the world's top central nervous system researchers and neurologists to provide a timely review of the most recent developments in ALS, covering historic aspects, experimental animal models, genetics, pathogenesis, clinical aspects and imagenology among others. Contributors from Belgium, France, Japan, India, Italy, Mexico, Russia, South Africa, and Switzerland have collaborated enthusiastically and efficiently, dedicating their time to create this reader-friendly yet comprehensive work which includes many explanatory figures, tables and photos to enhance legibility and make the book clinically useful. We are looking forward with confidence and pride in the remarkable role that this book will play for a new vision and mission.

Clinical Neurophysiology of Motor Neuron Diseases

Clinical Neurophysiology of Motor Neuron Diseases
  • Author : Andrew Eisen
  • Publisher :Unknown
  • Release Date :2004
  • Total pages :724
  • ISBN : 0444513590
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Summary : The volume summarizes the most recent knowledge in the field of motor system (upper and lower motor neuron) physiology and pathophysiology as related to diseases of this system. It covers the various aspects of motor system disorders from the motor cortex to the spinal anterior horn cell. Emphasis is placed on clinical disorders as they affect the human motor system and includes critical discussion of advances in techniques for diagnosing and understanding the pathophysiology of disorders affecting the motor system, describing approaches to characterization of disease type, location, severity and prognosis. There is discussion of the specificity and sensitivity of methodological techniques used in diagnosis, with comparison among the various methods.

Motor Neuron Disease

Motor Neuron Disease
  • Author : P.N. Leigh,Michael Swash
  • Publisher :Unknown
  • Release Date :2012-12-06
  • Total pages :468
  • ISBN : 9781447118718
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Summary : Here is the first book to provide a comprehensive overview of the clinical, pathological, and research aspects of motor neuron disease (MND). The text contains all essential features of the anatomy, physiology, pharmacology and toxicology of the motor system, a full description of MND and its variants, as well as historical developments and a review of the current concepts and controversies. This book comes at a time of increasing interest in neurodegenerative disorders and MND in particular. It will prove a key reference book with an integrated overview of the field, and will be indispensable to practicing neurologists, researchers, and all those with an interest in MND.

United States Code

United States Code
  • Author : United States
  • Publisher :Unknown
  • Release Date :2011
  • Total pages :229
  • ISBN : UOM:39015090675136
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Summary :

Clinical Cases in Neurology

Clinical Cases in Neurology
  • Author : Anthony Henry Vernon Schapira,Lewis P. Rowland
  • Publisher :Unknown
  • Release Date :2001
  • Total pages :261
  • ISBN : UOM:39015050171605
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Summary : * A guide to differential diagnosis of common neurological disorders * Illustrated case presentations are used to lead the reader through the process of differential diagnosis * Multi-contributed under the editorship of two leading neurologists from the UK and US * A guide to differential diagnosis of common neurological disorders * Illustrated case presentations are used to lead the reader through the process of differential diagnosis * Clinical advice includes details of which management options to consider and their use in practice

Cumulated Index Medicus

Cumulated Index Medicus
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :1992
  • Total pages :229
  • ISBN : UIUC:30112023523092
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Summary :

Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis
  • Author : Muralidhar L. Hegde
  • Publisher :Unknown
  • Release Date :2020-08-26
  • Total pages :160
  • ISBN : 9781838805807
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Summary : A flurry of recent research on the role of the RNA/DNA-binding proteins TDP-43 and FUS as well as a dozen other factors (e.g., C9ORF72 and profilin) has led to a new paradigm in our understanding of the pathobiology of the motor neuron disease, Amyotrophic Lateral Sclerosis (ALS). How these factors trigger neuromuscular dysfunction is critical for developing more effective ALS therapeutics. The ‘gain-of-toxicity’ or ‘loss-of-function’ of these etiological factors is a key question. Recent studies on the imbalance in genome damage versus repair have opened avenues for potential DNA repair-based therapeutics. This book highlights emerging science in the area of ALS and discusses key approaches and mechanisms essential for developing a cure for ALS.

Prognosis of Neurological Diseases

Prognosis of Neurological Diseases
  • Author : Angelo Sghirlanzoni,Giuseppe Lauria,Luisa Chiapparini
  • Publisher :Unknown
  • Release Date :2015-11-19
  • Total pages :519
  • ISBN : 9788847057555
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Summary : This book offers clear, detailed guidance on all aspects of prognostic evaluation in patients who have been involved in a serious accident with neurological consequences or have been diagnosed with a severe neurological illness. It covers the full range of disorders of the central and the peripheral nervous system, not only providing very accurate prognostic estimates but also addressing relevant clinical issues, differential diagnosis, and the role of imaging. The book is practically oriented and designed for use on a daily basis when assessing prognosis and discussing the outcome with patients, their families, and other interested parties. It will support patient–doctor partnerships by ensuring that the most professional answers can be given to patients' and doctors' questions and by promoting realistic expectations of the effect of medical interventions. In addition, it will enable doctors, lawyers, and other professionals to understand relevant issues when an estimate of prognosis and life expectancy is the subject of legal dispute.

Acupuncture in Neurological Conditions E-Book

Acupuncture in Neurological Conditions E-Book
  • Author : Val Hopwood,Clare Donnellan
  • Publisher :Unknown
  • Release Date :2010-07-23
  • Total pages :232
  • ISBN : 9780702049941
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Summary : Written by two leading experts in the field, Acupuncture in Neurological Conditions aims to improve patient care by combining Western and Traditional Chinese Medicine (TCM) concepts of treatment. The language of TCM is uniquely combined with that of evidence-based clinical reasoning to provide an approach relevant to both acupuncture and physiotherapy clinical practice. All major types of neurological conditions encountered in clinical practical are examined. Chinese medical patterns relevant to the application of acupuncture are described, as well as key patterns of dysfunction based on a Western medical perspective. The place of acupuncture within the overall management of different neurological conditions is also discussed. Clinical reasoning options from both TCM and Western medical perspectives are provided, and illustrated by real cases from clinical practice forming a sound platform for true integrated medicine. Fully evidence-based Provides clinical reasoning options from TCM and Western medical perspectives Illustrates clinical reasoning with real cases from clinical practice Provides detailed examination of all major types of neurological conditions encountered in clinical practice.

Motor Neuron Disease

Motor Neuron Disease
  • Author : Ralph W. Kuncl
  • Publisher :Unknown
  • Release Date :2002
  • Total pages :198
  • ISBN : 0702025283
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Summary : Motor neuron disease is a neurological condition that usually begins in late life. It comprises several different disorders that are characterized by degeneration and loss of motor neurons. Recent advances in this area include new information on the genetic components within MND, current pharmacotherapy, and the multidisciplinary approach to care.