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Multiple Sclerosis 3

Multiple Sclerosis 3
  • Author : Claudia F. Lucchinetti,Reinhard Hohlfeld
  • Publisher :Unknown
  • Release Date :2010
  • Total pages :463
  • ISBN : 1416060685
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Summary : Covers the latest clinical advances and relevant discussions, Biomarkers, Genomics, and Surrogate Outcomes in MS; Pediatric MS; Transverse Myelitis; Attack Therapies in MS; Current Disease-Modifying Therapeutic Strategies in MS; Management of Aggressive MS; Symptomatic Therapies in MS; Complementary and Alternative Medical Therapies; and Strategies to Promote Neuroprotection and Repair, to bring you up to date and keep your practice state-of-the-art. Features a greater emphasis on practical management to help you determine the type of multiple sclerosis and the best course of therapy. Focuses on pharmaceutical therapies so you know the best and most aggressive methods and which drugs to use for treatment. Includes extensive information on differential diagnosis so that you can clearly distinguish between multiple sclerosis and other similar demyelinating disorders. Presents expert new editors and experienced contributing authors for the most current and relevant practice information.-

Multiple Sclerosis 3, Volume 34 E-Book

Multiple Sclerosis 3, Volume 34 E-Book
  • Author : Claudia Lucchinetti,Reinhard Hohlfeld
  • Publisher :Unknown
  • Release Date :2009-10-29
  • Total pages :496
  • ISBN : 9781437711295
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Summary : Multiple Sclerosis 3 emphasizes the latest in the pharmacologic treatment of this incurable inflammatory demyelinating disorder. Primary editors Claudia Lucchinetti, MD, and Reinhard Hohlfeld, MD, with the aid of all new contributors, present a complete and current reference on multiple sclerosis that includes discussions of such hot topics as Biomarkers, Genomics, and Surrogate Outcomes in MS; Pediatric MS; Transverse Myelitis; Attack Therapies in MS; Current Disease-Modifying Therapeutic Strategies in MS; Management of Aggressive MS; Symptomatic Therapies in MS; Complementary and Alternative Medical Therapies; and Strategies to Promote Neuroprotection and Repair. Distinguish between MS and other similar demyelinating disorders and know the best and most aggressive methods of treatment. This title in the Blue Books of Neurology series is exactly what you need to treat the disease and its relapses. Covers the latest clinical advances and relevant discussions—Biomarkers, Genomics, and Surrogate Outcomes in MS; Pediatric MS; Transverse Myelitis; Attack Therapies in MS; Current Disease-Modifying Therapeutic Strategies in MS; Management of Aggressive MS; Symptomatic Therapies in MS; Complementary and Alternative Medical Therapies; and Strategies to Promote Neuroprotection and Repair—to bring you up to date and keep your practice state-of-the-art. Features a greater emphasis on practical management to help you determine the type of multiple sclerosis and the best course of therapy. Focuses on pharmaceutical therapies so you know the best and most aggressive methods and which drugs to use for treatment. Includes extensive information on differential diagnosis so that you can clearly distinguish between multiple sclerosis and other similar demyelinating disorders. Presents expert new editors and experienced contributing authors for the most current and relevant practice information. Emphasizes the pharmacologic management of patients with multiple sclerosis to address treating the actual disease and its relapses as well as treating the symptoms.

Multiple Sclerosis

Multiple Sclerosis
  • Author : Institute of Medicine,Board on Neuroscience and Behavioral Health,Committee on Multiple Sclerosis: Current Status and Strategies for the Future
  • Publisher :Unknown
  • Release Date :2001-08-10
  • Total pages :456
  • ISBN : 9780309072854
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Summary : Multiple sclerosis is a chronic and often disabling disease of the nervous system, affecting about 1 million people worldwide. Even though it has been known for over a hundred years, no cause or cure has yet been discovered-but now there is hope. New therapies have been shown to slow the disease progress in some patients, and the pace of discoveries about the cellular machinery of the brain and spinal cord has accelerated. This book presents a comprehensive overview of multiple sclerosis today, as researchers seek to understand its processes, develop therapies that will slow or halt the disease and perhaps repair damage, offer relief for specific symptoms, and improve the abilities of MS patients to function in their daily lives. The panel reviews existing knowledge and identifies key research questions, focusing on: Research strategies that have the greatest potential to understand the bio- logical mechanisms of recovery and to translate findings into specific strategies for therapy. How people adapt to MS and the research needed to improve the lives of people with MS. Management of disease symptoms (cognitive impairment, depression, spasticity, vision problems, and others). The committee also discusses ways to build and financially support the MS research enterprise, including a look at challenges inherent in designing clinical trials. This book will be important to MS researchers, research funders, health care advocates for MS research and treatment, and interested patients and their families.

Textbook of Clinical Neurology

Textbook of Clinical Neurology
  • Author : Christopher G. Goetz
  • Publisher :Unknown
  • Release Date :2007
  • Total pages :1364
  • ISBN : 9781416036180
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Summary : The textbook's original structure has not changed. It remains anchored in the methods that neurologists utilize on a daily basis to approach, diagnose, and treat patients.

Multiple Sclerosis Therapeutics

Multiple Sclerosis Therapeutics
  • Author : Jeffrey A. Cohen,Richard A. Rudick
  • Publisher :Unknown
  • Release Date :2011-10-20
  • Total pages :229
  • ISBN : 9781139502375
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Summary : This book comprehensively reviews the current state of clinical trial methods in multiple sclerosis treatment, providing investigators, sponsors and specialists with current knowledge of outcome measures and study designs for disease and symptom management. The status of the rapidly evolving field of disease-modifying drugs is presented, with emphasis on the most promising therapies currently being tested. Experts discuss disease and symptom management for MS subtypes, including neuromyelitis optica and pediatric MS. In addition, key scientific advances in MS pathology, genetics, immunology and epidemiology are presented. The fourth edition has been extensively revised, featuring more than 50% new material. All chapters have been substantially updated to provide current information on rapidly evolving topics and this volume contains 15 new chapters, reflecting the growth of the field in recent years. This book is an essential reference for practitioners caring for MS patients, investigators planning or conducting clinical trials, and clinical trial sponsors.

Multiple Sclerosis and Related Disorders

Multiple Sclerosis and Related Disorders
  • Author : Douglas S. Goodin
  • Publisher :Unknown
  • Release Date :2014-02-05
  • Total pages :736
  • ISBN : 9780444633095
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Summary : Multiple Sclerosis (MS) is generally understood to be an inflammatory autoimmune disease of the central nervous system. While we still are not certain of the root cause of MS, research results suggest that unknown environmental factors and the presence of specific genes seem the most probable targets. MS causes an inflammatory response in the central nervous system leading to neurodegeneration, oligodendrocyte death, axonal damage, and gliosis. Over the past five years ongoing research has greatly expanded our understanding of the pathogenesis of MS, detailed insight into the epidemiology and genetic factors related to MS, the introduction of new technologies and tests to better diagnose and predict the future course of the disease and the introduction of new treatments targeting MS. This collection of review chapters provides a comprehensive reference into the science and clinical applications of the latest Multiple Sclerosis research and will be a valuable resource for the neuroscience research community and the clinical neurology community of researchers and practitioners. A comprehensive tutorial reference detailing our current foundational understanding of Multiple Sclerosis Includes chapters on key topics including the genetics of MS, MRI imaging and MS, and the latest treatment options Each chapter is translational and focuses on current research and impact on diagnosis and treatment options

Translational Neuroimmunology in Multiple Sclerosis

Translational Neuroimmunology in Multiple Sclerosis
  • Author : Ruth Arnon,Ariel Miller
  • Publisher :Unknown
  • Release Date :2016-05-10
  • Total pages :502
  • ISBN : 9780128020074
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Summary : Multiple sclerosis (MS) is the most common disabling neurological disease of young adults. More than 2.3 million people are affected by MS worldwide. Symptoms can vary widely, depending on the localization and amount of the damage induced by combined inflammatory, demyelinating, and neurodegenerative processes. Although a cure for MS does not currently exist, therapies can help treat MS attacks, attenuate disease activity, reduce progress of the disease, and manage symptoms. Translational Neuroimmunology in Multiple Sclerosis provides an overview of recent findings and knowledge of the neuroimmunology of multiple sclerosis, from experimental models and the human disease to the translation of this research to immunotherapeutic strategies. Chapters describe genetic and environmental factors underlying the disease pathogenesis of MS as a basis for development of immunotherapies, immunological markers of disease activity, pharmacogenetics, and responses to therapy. Immunomodulatory therapies currently in practice and future therapeutic strategies on the horizon—such as neuroprotective strategies, stem cells, and repair promotion—are discussed. Contributed by renowned leaders in the field, this cross-disciplinary volume is a great resource for basic scientists and clinical practitioners in neuroscience, neurology, immunology, pharmacology, and in-drug development. Provides an overview of recent findings and knowledge of the neuroimmunology of multiple sclerosis and the translation of this research to immunotherapy treatment Edited by renowned leaders in the field of neuroimmunology and multiple sclerosis Contains the latest resource material for basic and clinical scientists and practitioners in neuroscience, neurology, immunology, and pharmacology

Multiple Sclerosis

Multiple Sclerosis
  • Author : Rheinard Hohlfeld,Chris Polman,Alan J Thompson
  • Publisher :Unknown
  • Release Date :1997-01-01
  • Total pages :372
  • ISBN : 1853174289
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Summary : This excellent book provides a fresh approach to multiple sclerosis, detailing the newest developments in a lively style. Particular emphasis is placed on areas of controversy and uncertainty The information conveyed is accessible to all practitioners in the field of multiple sclerosis.

Multiple Sclerosis

Multiple Sclerosis
  • Author : Rosalind C. Kalb, MD
  • Publisher :Unknown
  • Release Date :2005-09-01
  • Total pages :222
  • ISBN : 193455930X
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Summary : Because most people who are diagnosed with MS are between the ages of 15-55 years, the disease has a significant impact, not only on the individual with the disease, but also on the family members and loved ones whose lives are interwoven with them. Families experiencing multiple sclerosis often find themselves in uncharted territory. Prior patterns of interacting with each other may no longer work; roles often shift with dramatic emotional impact; guilt, anger, sadness, and a sense of burden may create a barrier to intimacy, joy, growth, and family unity. There are ways out of this debilitating situation, and many families have restored their balance, humor, productivity and family solidarity. Multiple Sclerosis: A Guide for Families can lead the way for your family to strengthen its coping skills and to receive targeted information about the disease and its ramifications. This complete yet highly readable guide for families living with multiple sclerosis addresses these issues and more. Families must learn how to strike a reasonable balance between the interests and needs of its members, and to accommodate the limitations imposed by MS without allowing them to impact every aspect of family life. This is easier said than done, and extensive discussions consider how the basic goals of living with this chronic disease can be met.

Multiple Sclerosis

Multiple Sclerosis
  • Author : Dr. T. Jock Murray, MS
  • Publisher :Unknown
  • Release Date :2004-12-01
  • Total pages :264
  • ISBN : 193455927X
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Summary : Multiple Sclerosis: The History of a Disease won a 2005 ForeWord Book of the Year Silver Medal! The basic facts about multiple sclerosis are well known: it is the most common neurologic disease of young adults, usually beginning with episodic attacks of neurologic symptoms, then entering a progressive phase some years later. Its onset has an average age of 30, and occurs in about 1 in 500 individuals of European ancestry living primarily in temperate climates. There appears to be a complex interaction between a genetic predisposition and an environmental trigger that initiates the disease. But these facts do not convey the impact of the disease on the people whose lives it affects. In this elegantly written and comprehensive history, we meet individuals who suffered with MS in the centuries before the disease had a name, including blessed Lidwina of Holland, who took joy from her misery, believing that she was sent to accept suffering for the sins of others; Augustus d'Est, grandson of George III and cousin of Queen Victoria, whose case shows how someone with access to the best of medical care of the age was understood and managed; and Heinrich Heine, the great German poet, who also had access to all medical services that were available, but who progressed into his mattress grave in two decades, aware of the loss of physical ability while still able to compose great poetry to the end. From these early cases the author demonstrates how progress in diagnosing and managing multiple sclerosis has paralleled the development of medical science, from the early developments in modern studies of anatomy and pathology, to the framing of the disease in the nineteenth century, and eventually to modern diagnosis and treatment. From beginning to end, Dr. Murray takes us on a fascinating journey of discovery, in the process showing how the evolution of our understanding of multiple sclerosis has been part of the greater history of medical knowledge.

Multiple Sclerosis

Multiple Sclerosis
  • Author : Paul O'Connor
  • Publisher :Unknown
  • Release Date :2002
  • Total pages :155
  • ISBN : 1552635287
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Summary : Multiple Sclerosis-MS-strikes about one in a thousand North Americans, usually in early adulthood, when they are building careers and starting families. In the wholly revised and updated edition of Multiple Sclerosis: The Facts You Need, readers will find a fact-filled, comprehensive guide to living with MS. The accessible text is supported by diagrams, case histories, a drug table and an extensive list of helpful books and organizations. Topics include: what MS is, and who gets it; how MS is diagnosed as 'possible,' 'probable' or 'definite'; why the disease affects different people in different ways; how 'relapsing-remitting' MS differs from 'progressive' MS; how people with MS, and their families, can adapt their homes, careers and lifestyles to cope with the disease; which treatments work, which don't and what is on the horizon. This edition of Multiple Sclerosis has been revised to incorporate new findings related to the diagnosis and treatment of MS, including very early as well as more advanced disease. Additional information has also been included on the treatment of fatigue among other symptoms.

Multiple Sclerosis As A Neuronal Disease

Multiple Sclerosis As A Neuronal Disease
  • Author : Stephen Waxman
  • Publisher :Unknown
  • Release Date :2005-05-27
  • Total pages :496
  • ISBN : 0080489419
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Summary : This book examines the role of neurons in multiple sclerosis (MS) and the changes that occur in neurons as a result of MS. It places MS in a new and important perspective that not only explains the basis for symptom production, remission, and progress in MS, but also promises to open up new therapeutic possibilities. * Brings together the latest information from clinical, pathological, imaging, molecular, and pharmacological realms to explore the neurobiology of Multiple Sclerosis * Places MS in a new and important perspective that promises to open up new therapeutic avenues * Superbly illustrated and referenced

Trending Topics in Multiple Sclerosis

Trending Topics in Multiple Sclerosis
  • Author : Alina Gonzalez-Quevedo
  • Publisher :Unknown
  • Release Date :2016-09-08
  • Total pages :338
  • ISBN : 9789535126560
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Summary : Multiple sclerosis (MS) is a chronic inflammatory disease characterized by progressive demyelination and neurodegeneration of the central nervous system (CNS), constituting the most common demyelinating disease of the CNS in humans. Although intensive research over many decades has unveiled many pathophysiological mechanisms in the development of MS, the cause is still unknown. Nevertheless, it does seem clear that genetic susceptibility and environmental factors play crucial roles. Trending Topics in Multiple Sclerosis is a book that provides an insight into some of the main problems currently debated in this area of research, focusing on topics that deal with genetic and environmental risk factors, pathophysiological mechanisms, neurocognitive findings, and neuroprotective strategies.

Emerging Drugs and Targets for Multiple Sclerosis

Emerging Drugs and Targets for Multiple Sclerosis
  • Author : Ana Martinez
  • Publisher :Unknown
  • Release Date :2019-06-28
  • Total pages :333
  • ISBN : 9781788014502
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Summary : Multiple sclerosis (MS) is a complex disease with a presumed autoimmune aetiology and few current effective treatments. Disease modifying therapies focus on the altering the natural course of relapsing and remitting MS, targeting the inflammatory response. Other targets involve tacking the cause of the disease – demyelination of axons through remyelination therapies. Due to several recent breakthroughs in the understanding of the pathophysiology of MS new targets for remyelination and immunomodulation are rapidly emerging. This book provides a comprehensive overview of drug discovery and development for the molecular basis of the disease, from new targets to drugs currently in clinical development, cellular and animal disease models to biomarkers for diagnosis and assessment in clinical trials. Emerging Drugs and Targets for Multiple Sclerosis is an ideal reference for any student or researcher interested in drug development for neurodegenerative diseases, autoimmune diseases and MS in particular.

Neuroimmunology for the Clinician

Neuroimmunology for the Clinician
  • Author : Loren A. Rolak,Harati Yadollah
  • Publisher :Unknown
  • Release Date :1997
  • Total pages :440
  • ISBN : UOM:39015040988340
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Summary : With 24 contributing authors. This practical guide explains in simple clinical terms the important immunology and therapy needed for the neurologist to confidently diagnose and treat patients with neuroimmunologic problems. * -User friendly treatment of a difficult subject: practical, simple, and comprehensive * - Practical guide to how to diagnose and treat immunologic diseases of the nervous system *

The Multiple Sclerosis Diet Book

The Multiple Sclerosis Diet Book
  • Author : Roy Laver Swank,Barbara Brewer Dugan
  • Publisher :Unknown
  • Release Date :2011-06-08
  • Total pages :416
  • ISBN : 9780307797407
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Summary : Swank and Dugan provide complete background information on the development of the diet and the clinical tests that have proven its effectiveness. In addition to helpful sections on the lifestyle of the M.S. patient, Swank and Dugan offer tips on sticking to the diet, equipping the kitchen, shopping for healthful food, eating out (with some pertinent information on fast-food restaurants), and keeping the careful dietary records that are essential to continuing good nutrition. This is the low-fat diet that works in reducing the number and severity of relapses in M.S. patients — and The Multiple Sclerosis Diet Book provides the nutritious and tasty recipes that M.S. patients and their families can live with for years to come.

Multiple Sclerosis

Multiple Sclerosis
  • Author : Gary Birnbaum
  • Publisher :Unknown
  • Release Date :2013-05-23
  • Total pages :128
  • ISBN : 9780199840786
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Summary : Designed to help busy clinicians understand and implement the most current, evidence-based diagnostic and treatment approaches, Multiple Sclerosis: Clinician's Guide to Diagnosis and Treatment considers the disease in its totality, epidemiology, classification, patterns and pathophysiology, complications and comorbidities, and management and therapy.

Nursing Practice in Multiple Sclerosis, Third Edition

Nursing Practice in Multiple Sclerosis, Third Edition
  • Author : June Halper,Colleen Harris
  • Publisher :Unknown
  • Release Date :2011-11-22
  • Total pages :232
  • ISBN : 9780826119278
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Summary : Print+CourseSmart

Molecular Basis of Multiple Sclerosis

Molecular Basis of Multiple Sclerosis
  • Author : Roland Martin,Andreas Lutterotti
  • Publisher :Unknown
  • Release Date :2010-09-14
  • Total pages :308
  • ISBN : 3642141536
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Summary : Despite major efforts by the scientific community over the years, our understanding of the pathogenesis or the mechanisms of injury of multiple sclerosis is still limited. Consequently, the current strategies for treatment and management of patients are limited in their efficacy. The mechanisms of tissue protection and repair are probably even less understood. One reason for these limitations is the enormous complexity of the disease and every facet of its pathogenesis, the mechanisms of tissue injury, the diagnostic procedures and finally the efficacy of treatments and their side effects. The aim of this book is to review the most recent advances made in this highly complex field.

Multiple Sclerosis, Mad Cow Disease and Acinetobacter

Multiple Sclerosis, Mad Cow Disease and Acinetobacter
  • Author : Alan Ebringer
  • Publisher :Unknown
  • Release Date :2014-11-19
  • Total pages :200
  • ISBN : 9783319027357
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Summary : The aim of this book is to publicise and bring to a wider audience the concept that the cause of two neurological diseases, namely multiple sclerosis (MS) and “mad cow disease” also known as “bovine spongiform encephalopathy” are related through exposure to a common microbe Acinetobacter which is found in human sinuses, on skin and in the soil. An infection is the cause of a neurological disease in man and in animals. Elevated levels of antibodies to Acinetobacter have been found in multiple sclerosis patients as well as in ruminants who have been described as suffering from “mad cow disease” following exposure to contaminated feed supplements. The overall objective and scope of this book is to inform the audience, the reader, that multiple sclerosis may be linked to a microbe Acinetobacter which carries molecular structures resembling myelin, the outer sheath covering of neurons.

Multiple Sclerosis

Multiple Sclerosis
  • Author : Douglas McAlpine,Charles Edward Lumsden,Donald Acheson
  • Publisher :Unknown
  • Release Date :1972
  • Total pages :653
  • ISBN : UOM:39015000302516
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Summary :