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Evolving Neural Crest Cells

Evolving Neural Crest Cells
  • Author : Brian Frank Eames,Daniel Meulemans Medeiros,Igor Adameyko
  • Publisher :Unknown
  • Release Date :2020-07-28
  • Total pages :294
  • ISBN : 9781351805919
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Summary : Vertebrates possess lineage-specific characteristics. These include paired anterior sense organs and a robust, modular head skeleton built of cellular cartilage and bone. All of these structures are derived, at least partly, from an embryonic tissue unique vertebrates - the neural crest. The evolutionary history of the neural crest, and neural crest cells, has been difficult to reconstruct. This volume will use a comparative approach to survey the development of the neural crest in vertebrates, and neural crest-like cells, across the metazoa. This information will be used to reveal neural crest evolution and identify the genomic, genetic, and gene-regulatory changes that drove them. Key selling features: Summarizes the data regarding neural crest cells and nerural crest derivatives Uses a broad-based comparative approach Suggests hypothesis that the origin of neural crest cells involved the novel co-activation of ancient metazoan gene programs in neural border cells Illustrates how the emergences of neural crest made possible the diversification of vertebrate heads

Neural Crest Cells

Neural Crest Cells
  • Author : Paul Trainor
  • Publisher :Unknown
  • Release Date :2013-11-23
  • Total pages :488
  • ISBN : 9780124045866
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Summary : Neural Crest Cells: Evolution, Development and Disease summarizes discoveries of historical significance and provides in-depth, current analyses of the evolution of neural crest cells, their contribution to embryo development, and their roles in disease. In addition, prospects for tissue engineering, repair and regeneration are covered, offering a timely synthesis of the current knowledge in neural crest cell research. A comprehensive resource on neural crest cells for researchers studying cell biology, developmental biology, stem cells and neurobiology, Neural Crest Cells: Evolution, Development and Disease provides foundational information needed for students , practicing physicians and dentists treating patients with craniofacial defects. BMA Medical Book Awards 2014 - Highly Commended,Basic and Clinical Sciences,2014, British Medical Association Provides timely, comprehensive synthesis of the current knowledge of neural crest cells Covers the evolution and development of neural crest cells Includes content on applications for tissue engineering, repair and regeneration

The Neural Crest

The Neural Crest
  • Author : Nicole Le Douarin,Nicole M. LeDouarin,Chaya Kalcheim
  • Publisher :Unknown
  • Release Date :1999-11-28
  • Total pages :445
  • ISBN : 0521620104
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Summary : This 1999 edition of The Neural Crest contains comprehensive information about the neural crest, a structure unique to the vertebrate embryo, which has only a transient existence in early embryonic life. The ontogeny of the neural crest embodies the most important issues in developmental biology, as the neural crest is considered to have played a crucial role in evolution of the vertebrate phylum. Data that analyse neural crest ontogeny in murine and zebrafish embryos have been included in this revision. This revised edition also takes advantage of recent advances in our understanding of markers of neural crest cell subpopulations, and a full chapter is now devoted to cell lineage analysis. The major research breakthrough since the first edition has been the introduction of molecular biology to neural crest research, enabling an elucidation of many molecular mechanisms of neural crest development. This book is essential reading for students and researchers in developmental biology, cell biology, and neuroscience.

Neural Crest Cells

Neural Crest Cells
  • Author : Quenten Schwarz,Sophie Wiszniak
  • Publisher :Unknown
  • Release Date :2019-06-06
  • Total pages :230
  • ISBN : 1493994115
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Summary : This detailed book provides a wide range of techniques, from those that have been used extensively since the very first investigations into neural crest cells to those that are currently cutting-edge, in order to explore the development of neural crest cells in human, mice, rat, chick, quail, medaka, and shark. With a bit of imagination and adjustment, many of these methodologies can be adaptable to any species desirable for study. Written for the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Neural Crest Cells: Methods and Protocols serves as an ideal reference guide for aspiring and experienced developmental biologists alike.

Neural Crest Stem Cells

Neural Crest Stem Cells
  • Author : Maya Sieber-Blum
  • Publisher :Unknown
  • Release Date :2012
  • Total pages :156
  • ISBN : 9789814343817
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Summary : The book offers readers an understanding of the development of neural crest cells, which is crucial as many birth defects and tumours are of neural crest origin. The neural crest is a transient tissue of the vertebrate embryo. It originates from the future spinal cord and neural crest stem cells emigrate from this location to various places in the embryo, giving rise to many different cell types and tissues. Neural crest derivatives include the peripheral nervous systems, endocrine cells such as the adrenal medulla, smooth musculature of the cardiac outflow tract and great blood vessels, as well as craniofacial bone and cartilage. The underlying mechanisms that regulate embryonic neural crest development are still being investigated and are important for our understanding of neural crest pathologies. Readers will have ready access to current research topics, elaborated in great detail, with a focus on adult neural crest-derived stem cells, which persist in various locations of the postnatal organism. Delving into stem cells from different locations of the body, the book explores the best possible source of such cells for future use in medical applications.

Neural Crest Induction and Differentiation

Neural Crest Induction and Differentiation
  • Author : Jean-Pierre Saint-Jeannet
  • Publisher :Unknown
  • Release Date :2007-08-10
  • Total pages :248
  • ISBN : 9780387469546
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Summary : Written by an international panel of recognized leaders in the field, Neural Crest Induction and Differentiation discusses all aspects of modern neural crest biology from its evolutionary significance to its specification, migration, plasticity and contribution to multiple lineages of the vertebrate body, to the pathologies associated with abnormal neural crest development and function. Abundant color figures enhance the text providing clear and attractive illustrations of central issues and concepts.

The Neural Crest in Development and Evolution

The Neural Crest in Development and Evolution
  • Author : Brian K. Hall
  • Publisher :Unknown
  • Release Date :1999-07-30
  • Total pages :313
  • ISBN : 0387987029
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Summary : A discussion of the neural crest and neural crest cells, dealing with their discovery, their embryological and evolutionary origins, their cellular derivatives - in both agnathan and jawed vertebrates or gnathostomes - and the broad topics of migration and differentiation in normal development. The book also considers what goes wrong when development is misdirected by mutations, or by exposure of embryos to exogenous agents such as drugs, alcohol, or excess vitamin A, and includes discussions of tumours and syndromes and birth defects involving neural crest cells.

Transcriptional Control of Neural Crest Development

Transcriptional Control of Neural Crest Development
  • Author : Brian Nelms,Patricia Labosky
  • Publisher :Unknown
  • Release Date :2010-02-01
  • Total pages :227
  • ISBN : 9781615040490
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Summary : The neural crest is a remarkable embryonic population of cells found only in vertebrates and has the potential to give rise to many different cell types contributing throughout the body. These derivatives range from the mesenchymal bone and cartilage comprising the facial skeleton, to neuronal derivatives of the peripheral sensory and autonomic nervous systems, to melanocytes throughout the body, and to smooth muscle of the great arteries of the heart. For these cells to correctly progress from an unspecifi ed, nonmigratory population to a wide array of dynamic, differentiated cell types—some of which retain stem cell characteristics presumably to replenish these derivatives—requires a complex network of molecular switches to control the gene programs giving these cells their defi ning structural, enzymatic, migratory, and signaling capacities. This review will bring together current knowledge of neural crest-specifi c transcription factors governing these progressions throughout the course of development. A more thorough understanding of the mechanisms of transcriptional control in differentiation will aid in strategies designed to push undifferentiated cells toward a particular lineage, and unraveling these processes will help toward reprogramming cells from a differentiated to a more naive state. Table of Contents: Introduction / AP Genes / bHLH Genes / ETS Genes / Fox Genes / Homeobox Genes / Hox Genes / Lim Genes / Pax Genes / POU Domain Genes / RAR/RXR Genes / Smad Genes / Sox Genes / Zinc Finger Genes / Other Miscellaneous Genes / References / Author Biographies

Neural Crest and Placodes

Neural Crest and Placodes
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2015-02-03
  • Total pages :542
  • ISBN : 9780124078901
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Summary : Neural Crest and Placodes provides in-depth coverage of the topic, including information on their critical role in vertebrate development, evolution, and the way defects in their development underlie a wide range of congenital disorders. It delves deep into advances made in our understanding of the mechanisms governing the formation, migration, and differentiation of these two cell populations, also discussing their integration during embryonic development. The text highlights the application of fundamental knowledge in investigating the etiology and pathogenesis of congenital disorders and the ways the data applies to the field of regenerative medicine. Written by leading experts in the field Includes descriptions of the most recent advances in the field Highlights the applications of this knowledge in investigating the etiology and pathogenesis of congenital disorders Explores their usage in the field of regenerative medicine

Craniofacial Development

Craniofacial Development
  • Author : British Society for Developmental Biology. Meeting
  • Publisher :Unknown
  • Release Date :1988
  • Total pages :257
  • ISBN : UOM:39015013802106
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Summary :

The Neural Crest and Neural Crest Cells in Vertebrate Development and Evolution

The Neural Crest and Neural Crest Cells in Vertebrate Development and Evolution
  • Author : Brian K. Hall
  • Publisher :Unknown
  • Release Date :2008-12-28
  • Total pages :402
  • ISBN : 0387098461
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Summary : A presentation of all aspects of neural crest cell origins (embryological and evolutionary) development and evolution; neural crest cell behavior (migration) and anomalies (neurocristopathies and birth defects) that arise from defective neural crest development. The treatment of development will include discussions of cellular, molecular and genetic aspects of the differentiation and morphogenesis of neural crest cells and structures derived from neural crest cells. The origins of the neural crest in embryology will be discussed using the recent information on the molecular basis of the specification of the neural crest. Also presented are the advances in our understanding of the evolution of jaws from studies on lampreys and of the neural crest from studies on ascidians and amphioxus.

Neurotrophins and the Neural Crest

Neurotrophins and the Neural Crest
  • Author : Maya Sieber-Blum
  • Publisher :Unknown
  • Release Date :1998-06-29
  • Total pages :288
  • ISBN : 0849340047
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Summary : The target of much current research, the neural crest is a transitory tissue of the vertebrate embryo that gives rise to many diverse structures in the adult organism, including the autonomic nervous system, the enteric nervous system, and most primary sensory ganglia, among other cell types and tissues. Reflecting recent investigations, Neurotrophins and the Neural Crest is dedicated to the roles neurotrophins play in neural crest cell differentiation and in the survival of neural crest derivatives. This timely book correlates in vitro data with results obtained from knock-out mice with targeted neurotrophin or receptor deletions, with the goal of determining the fidelity and usefulness of various experimental culture systems. It also covers embryonic expression patterns and functions of neurotrophins and their receptors. Chapters are organized to begin with neural crest-derived tissues as sources for experimental material, including sensory neurons, sympathetic neurons, enteric neurons, melanocytes, and calcitonin-producing cells from the thyroid, and concludes with discussions of the neural crest cells. A broad range of researchers and scientists involved in growth factors, neuroscience, developmental and cell biology, embryology, and many other fields, will find that Neurotrophins and the Neural Crest targets this fast-moving area of research completely and concisely.

Review of Medical Embryology

Review of Medical Embryology
  • Author : Ben Pansky
  • Publisher :Unknown
  • Release Date :1982-08-01
  • Total pages :527
  • ISBN : 0071053034
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Summary :

Developmental and Evolutionary Aspects of the Neural Crest

Developmental and Evolutionary Aspects of the Neural Crest
  • Author : Paul F. A. Maderson
  • Publisher :Unknown
  • Release Date :1987-10-23
  • Total pages :394
  • ISBN : UOM:39015013230373
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Summary : Brings together important contributions by professionals in a range of fields. Its three major sections focus on the developmental biology of the neural crest; recent advances in this area, and how current insights are contributing to our understanding of the development and organization of the nervous system; and the relationship between the neural crest and skeletal evolution. Topics discussed include interactions between cephalic neural crest and mesodermal populations, the role of tissue interactions in the evolution of the vertebrate head, tooth development in the mammalian embryo in relation to the neural crest, and much more. Extensively illustrated with over 130 pieces of artwork.

Etiology and Morphogenesis of Congenital Heart Disease

Etiology and Morphogenesis of Congenital Heart Disease
  • Author : Toshio Nakanishi,Roger R. Markwald,H.Scott Baldwin,Bradley B. Keller,Deepak Srivastava,Hiroyuki Yamagishi
  • Publisher :Unknown
  • Release Date :2016-06-24
  • Total pages :383
  • ISBN : 9784431546283
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Summary : This volume focuses on the etiology and morphogenesis of congenital heart diseases. It reviews in detail the early development and differentiation of the heart, and later morphologic events of the cardiovascular system, covering a wide range of topics such as gene functions, growth factors, transcription factors and cellular interactions that are implicated in cardiac morphogenesis and congenital heart disease. This book also presents recent advances in stem cell and cell sheet tissue engineering technologies which have the potential to provide novel in vitro disease models and to generate regenerative paradigms for cardiac repair and regeneration. This is the ideal resource for physician scientists and investigators looking for updates on recent investigations on the origins of congenital heart disease and potential future therapies.

The Pigmentary System

The Pigmentary System
  • Author : James J. Nordlund,Raymond E. Boissy,Vincent J. Hearing,Richard A. King,William S. Oetting,Jean-Paul Ortonne
  • Publisher :Unknown
  • Release Date :2008-04-15
  • Total pages :1248
  • ISBN : 9781405157339
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Summary : The most comprehensive and integrated book on pigmentation The Pigmentary System, Second Edition, gathers into one convenient, all-inclusive volume a wealth of information about the science of pigmentation and all the common and rare clinical disorders that affect skin color. The two parts, physiology (science) and pathophysiology (clinical disorders), are complementary and annotated so that those reading one part can easily refer to relevant sections in the other. For the clinician interested in common or rare pigment disorders or the principles of teaching about such disorders, this book provides an immediate and complete resource on the biologic bases for these disorders. For the scientist studying the biology of melanocyte function, the book provides a list of disorders that are related to basic biological functions of melanocytes. New features of this Second Edition include: Completely new section on the basic science of pigmentation – explaining the integration of melanocyte functions with other epidermal cells and with various organ systems like the immune system New chapters on pigmentary disorders related to intestinal diseases, the malignant melanocyte, benign proliferations of melanocytes (nevi) and phototherapy with narrow band UV All clinical chapters include the latest genetic findings and advances in therapy More than 400 color images of virtually all clinical disorders The book is ideal for all dermatologists and especially those interested in disorders of pigmentation. It is of particular use for pediatric dermatologists and medical geneticists caring for patients with congenital and genetic pigmentary disorders. This authoritative volume will fill the gap for dermatology training programs that do not have local experts on pigmentation. Basic and cosmetic scientists studying pigmentation and melanocytes will find the science and clinical correlations very useful in showing human significance and relevance to the results of their studies.

Neuroblastoma

Neuroblastoma
  • Author : Chandrika Gowda
  • Publisher :Unknown
  • Release Date :2017-10-25
  • Total pages :168
  • ISBN : 9789535135838
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Summary : Neuroblastoma (NBL) is the most common extracranial solid tumor of childhood, with about 700 new cases of neuroblastoma seen each year in the United States. The 5-year survival rate for children with high-risk NBL is only 50-60%, and this survival rate has not improved over the last 10 years. High-risk patients receive multimodality treatment, including chemotherapy, surgery, radiation therapy, biologic therapy and immunotherapy, all of which are associated with significant morbidity. Recent years have seen many advances in treatment of neuroblastoma, including therapeutic MIBG, immunotherapy, and personalized targeted therapy based on the genetic alterations seen in the tumor. The primary objective of this book is to provide the readers with a comprehensive review of neuroblastoma, from clinical aspects and the currently available treatment to recent advancements and future directions in the field of NBL treatment. The topics and chapters have been compiled keeping in mind a diverse group of readers in different areas of specialty such as pediatric oncology, surgery, radiation oncology, and immunology, as well as physician scientists and basic researchers working in the field of neuroblastoma.

Perspectives of Stem Cells

Perspectives of Stem Cells
  • Author : Henning Ulrich
  • Publisher :Unknown
  • Release Date :2010-01-14
  • Total pages :290
  • ISBN : 9048133750
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Summary : Stem cells are fascinating cell types. They can replicate themselves forever while retaining the potential to generate progeny with speci?c functions. Because of these special properties, stem cells have been subjects of intensive investigation, from understanding basic mechanisms underlying tissue generation, to modeling human diseases, to application for cell replacement therapy. Stem cells come in different forms. For example, mouse embryonic stem cells can general all cell types in a body, either in a dish or when put back into mouse embryos. On the other hand, neural stem cells in the adult brain generate neurons and glia cells that contribute to the brain’s plasticity. Rapid progress has been made in the stem cell ?eld with discov- ies published in a record speed. A quick Pubmed search has returned 2789 hits for “embryonic stem cells” and 815 hits for “adult neural stem cells/neurogenesis” in the year 2008 alone. It remains a taunting task for all who are interested in stem cells to keep up with rapidly accumulating literatures. The “Perspectives of Stem Cells” by a truly international team of experts provides a timely and invaluable highlight of the stem cell ?eld gearing toward future therapeutic applications in the nervous system. Stem cells with neural potentials have attracted a lot of attention because of their promise for cell replacement therapy, ranging from degenerative neurological dis- ders to spinal cord injuries.

Stem Cells in Craniofacial Development and Regeneration

Stem Cells in Craniofacial Development and Regeneration
  • Author : George T.J. Huang,Irma Thesleff
  • Publisher :Unknown
  • Release Date :2013-02-15
  • Total pages :584
  • ISBN : 9781118498118
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Summary : Stem Cells, Craniofacial Development and Regeneration is anintroduction to stem cells with an emphasis on their role incraniofacial development. Divided into five sections, chaptersbuild from basic introductory information on the definition andcharacteristics of stem cells to more indepth explorations oftheir role in craniofacial development. Section I covers embryonicand adult stem cells with a focus on the craniofacial region, whilesections II-IV cover the development and regeneration ofcraniofacial bone, tooth, temporomandibular joint, salivary glandsand muscle. Concluding chapters describe the current, cutting-edgeresearch utilizing stem cells for craniofacial tissuebioengineering to treat lost or damaged tissue. The authoritative resource for dentistry students as well ascraniofacial researchers at the graduate and post-graduate level,Stem Cells, Craniofacial Development and Regenerationexplores the rapidly expanding field of stem cells and regenerationfrom the perspective of the dentistry and craniofacial community,and points the way forward in areas of tissue bioengineering andcraniofacial stem cell therapies.

Neural Stem Cells

Neural Stem Cells
  • Author : Tanja Zigova,Paul R. Sanberg,Juan R. Sanchez-Ramos
  • Publisher :Unknown
  • Release Date :2002
  • Total pages :400
  • ISBN : 9781592591862
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Summary : Provides you with reliable cellular, molecular, and electrophysiological methods to isolate, characterize, and utilize neural stem cells. These readily reproducible techniques introduce the various sources of stem/progenitor cells, provide a wide range of conditions for their culture, and make it possible to define their properties in culture. The protocols range from simple isolation and characterization of neural cell properties to sophisticated methods such as characterizing gene expression, telomerase assays, and cell cycle kinetics.

The Biology of Schwann Cells

The Biology of Schwann Cells
  • Author : Patricia Armati
  • Publisher :Unknown
  • Release Date :2007-02-15
  • Total pages :229
  • ISBN : 9781139462099
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Summary : Schwann cells are a diverse group of cells formed from neural crest cells. They are essential components of the peripheral nerves of both vertebrate and invertebrate nervous systems. The diversity of Schwann cell subsets and function is seen in those Schwann cells that form myelin - that uniquely specialised part of the plasma membrane that spirals around axonal lengths to myelinate the peripheral nerves. The Biology of Schwann Cells concentrates on the cells of mammals and in particular humans. It covers the distinction between compact and non-compact myelin in depth, along with the perisynaptic cells which form the partnership between nerve terminals and muscle fibre. Developmental aspects are discussed alongside differentiation, and the genetics of the cells in health and disease. With chapters from world-renowned experts, this book is aimed at postgraduates and researchers in neuroscience and neurology and anyone involved in the study of peripheral nerves.