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Neuroblastoma

Neuroblastoma
  • Author : Carl E. Pochedly
  • Publisher :Unknown
  • Release Date :1990-06-21
  • Total pages :424
  • ISBN : 0849301572
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Summary : The purpose of this book is to provide a comprehensive review of current knowledge and to give a thoughtful assessment of the many complex issues involved in the diagnosis and treatment of this common malignant solid tumor found in children. This up-to-date publication also reviews new concepts in histogenesis and histopathology of neuroblastoma. Divided into three main sections, this work focuses on tumor biology, clinical management, and prognosis and future perspectives. This fascinating work includes in-depth discussions on neuroblastoma in infancy and the manifestations of this tumor as it affects various organs and various parts of the body. It also provides guidelines for treatment with surgery, radiotherapy and chemotherapy. This ideal resource is loaded with information for all those who care for children with cancer, including pediatric oncologists, medical oncologists, pathologists, radiotherapists, pediatric nurse oncologists and pediatricians.

Neuroblastoma

Neuroblastoma
  • Author : Sabine Sarnacki,Luca Pio
  • Publisher :Unknown
  • Release Date :2019-08-12
  • Total pages :383
  • ISBN : 9783030183967
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Summary : This book addresses neuroblastoma, a type of embryonic tumor derived from neural crest cells and one of the most frequent extra-cranial solid tumors in children. However, the term also describes a heterogeneous group of tumors, the prognosis of which can differ greatly according to age, stage and biology. Some forms undergo spontaneous regression, and some are cured by surgery alone or after chemo-reduction, while others exhibit extremely aggressive behavior. Their successful treatment is one of the best examples of tailored medicine, which involves close collaboration between pediatric surgeons, pediatric oncologists, radiologists, nuclear medicine specialists, biologists, oncogeneticists and radiotherapists. The book pursues a unique approach, as it combines most essential insights from all of these fields, together with key information regarding epidemiology, physiopathology and palliative care. The respective chapters were written by the leading international experts on neuroblastoma, and present the latest advances in terms of research, surgical approaches and medical treatments. The book offers an invaluable resource to all pediatric surgeons, pediatricians, oncologists, students, researchers and all others involved in neuroblastoma management who want to benefit from their colleagues’ expertise.

Focus on Neuroblastoma Research

Focus on Neuroblastoma Research
  • Author : Julio A. Fernandes
  • Publisher :Unknown
  • Release Date :2007
  • Total pages :212
  • ISBN : 1600214843
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Summary : Neuroblastoma is a cancer that develops from nerve cells found in several areas of the body. Neuroblastoma most commonly affects children age 5 or younger, though it may rarely occur in older children and adults. Neuroblastoma is the most common cancer in babies. Neuroblastoma develops in tissue that makes up the sympathetic nervous system -- the system of nerves that automatically regulates your heart rate, blood pressure and digestion. Neuroblastoma most commonly arises in and around the adrenal glands, which sit atop the kidneys. However, Neuroblastoma can also develop in other areas of the abdomen and in the chest, neck and pelvis. This book presents important research in this field of research.

Neuroblastoma

Neuroblastoma
  • Author : Nai-Kong V. Cheung,Susan L. Cohn
  • Publisher :Unknown
  • Release Date :2006-03-30
  • Total pages :300
  • ISBN : 9783540266167
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Summary : Neuroblastoma is a medical enigma. As a childhood neoplasm arising from neural crest cells, it is characterized by diverse clinical behaviors ranging from spontaneous remission to rapid tumor progression and death. Although clinical outcome can be predicted to a large extent by the stage of disease and the age at diagnosis, an in-depth understanding of its clinico-pathological behavior, now greatly aided by sophisticated molecular genetic profiling, will improve diagnostic precision and refine risk-based therapies. Comprehensive international efforts have advanced our understanding of tumor biology and improved the clinical management of children with neuroblastoma. This book reviews our current understanding of the genes and biological pathways that contribute to neuroblastoma pathogenesis, modern risk-based treatment approaches for these patients, and recent advances in biologically based therapy. It provides a concise up-to-date reference for practitioners, students, and researchers.

The Neurology of Neuroblastoma

The Neurology of Neuroblastoma
  • Author : Nina Felice Schor
  • Publisher :Unknown
  • Release Date :2012-12-06
  • Total pages :90
  • ISBN : 9781461510574
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Summary : Neuroblastoma is the single most common solid tumor of childhood. Although children with small primary neuroblastomas alone are almost always cured by surgery, 65% of children with neuroblastoma already have large bulky tumors or metastatic disease by the time of initial diagnosis. For these children, the 5-year survival rate is only somewhere between 5% and 20% with therapies including surgery, radiation, chemotherapy, and bone marrow transplantation. Dr Schor outlines a new approach to these tumors in order to make a difference for these children. There is much information to support the notion that neuroblastomas represent a developmental aberration of the nervous system, rather than a de novo abnormality in a previously normal cell. While the remote, paraneoplastic effects of neuroblastoma are often the purview of the child neurologist, the neoplasm itself has been viewed and approached therapeutically in much the same manner as all other solid tumors, as the purview of the pediatric oncologist. This work takes the view that approaching neuroblastoma rather as a disorder of nervous system development offers new therapeutic possibilities for this common tumor of childhood.

Neuroblastoma

Neuroblastoma
  • Author : Hiroyuki Shimada
  • Publisher :Unknown
  • Release Date :2012-02-08
  • Total pages :378
  • ISBN : 9789533070162
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Summary : Neuroblastoma, once called "enigmatic", due to "unpredictable" clinical behaviors, is composed of biologically diverse tumors. Molecular/genomic properties unique to the individual tumors closely link to the clinical outcomes of patients. Establishing risk stratification models after analyzing biologic characteristics of each case has made a great success in patient management. However, the trend of improving survival rates in neuroblastoma over the last 30 years has started to level off, and currently available treatment modalities have almost reached to their maximized intensity. Furthermore, aggressive treatment causes significant long-term morbidities to the survivors. We really need to make the next step to the level of personalized medicine with more precise understanding of neuroblastoma biology. This book includes useful data and insights from the world's experts in this field. I believe this book can make an excellent contribution to all the investigators working hard and fighting for the children stricken by this disease.

Neuroblastoma

Neuroblastoma
  • Author : Judy S.E. Moyes,V. Ralph McCready,Ann C. Fullbrook
  • Publisher :Unknown
  • Release Date :2012-12-06
  • Total pages :168
  • ISBN : 9781447116745
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Summary : The use of metaiodobenzylguanidine as a radiopharmaceutical offers exciting new possibilities, and well-known authorities share their experience in this volume. It is designed as a practical aid for those who are starting to employ the relatively new method of mIGB in the diagnosis and treatment of neuroblastoma. Profusely illustrated case histories demonstrate the normal and pathological uptake of mIGB and assist the beginner to correctly interpret the scintigrams. Details of the techniques for assessing the radiation dose to the tumors undergoing targetted radiotherapy are given, and the practical details required for its safe use in the pediatric environment are discussed.

Neuroblastoma

Neuroblastoma
  • Author : M.A. Hayat
  • Publisher :Unknown
  • Release Date :2011-11-02
  • Total pages :262
  • ISBN : 9400724187
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Summary : Introduction of new technologies and their applications to neuroblastoma diagnosis, treatment, and therapy assessment are explained. Role of molecular ghenetics in diagnosis and therapy for neuroblastoma patients is detailed. Molecular detection of minimal residual neuroblastoma is described. Magnetic resonance imaging and spectroscopy are detailed for diagnosing this solid, extracranial cancer. Targets for therapeutic intervention in neuroblastoma are identified, including targeting multidrug resistance in this cancer. Ornithine decarboxylase and polyamines are novel targets for therapeutic intervention. The effectiveness of chemotherapy with oral irinotecan and temozolomide is explained. The role of transcription factors (GATA) in neuroblastoma pregression is also included.

Neuroblastoma

Neuroblastoma
  • Author : Swapan K. Ray
  • Publisher :Unknown
  • Release Date :2019-01-11
  • Total pages :334
  • ISBN : 9780128120040
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Summary : Neuroblastoma: Molecular Mechanisms and Therapeutic Interventions comprehensively reviews current concepts in molecular and histopathological mechanisms that influence the growth of human malignant neuroblastoma, along with exciting therapeutic interventions. This book features a broad collection of contributions from leading investigators in histopathology, molecular mechanisms, genetics, epigenetics, microRNAs, proteomics, and metabolism in controlling growth and death in neuroblastoma. Recent developments in therapeutic interventions for neuroblastoma are also covered extensively, including chapters on surgery, chemotherapy, targeted therapy and immunotherapy. This book is ideal for advanced undergraduate students, graduate students, medical students, postdoctoral fellows, and investigators with an interest in current molecular concepts and therapeutic interventions. Comprehensively covers the histopathological characterization, molecular mechanisms, and most recent therapeutic interventions in neuroblastoma Includes recent developments and therapeutic interventions for neuroblastoma, including chapters on surgery, chemotherapy, targeted therapy and immunotherapy Presents a broad scope that provides basic researchers, practitioners and students with the most current overview of recent advances

Neuroblastomas: New Insights for the Healthcare Professional: 2011 Edition

Neuroblastomas: New Insights for the Healthcare Professional: 2011 Edition
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2012-01-09
  • Total pages :152
  • ISBN : 9781464901744
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Summary : Neuroblastomas: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Neuroblastomas. The editors have built Neuroblastomas: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Neuroblastomas in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Neuroblastomas: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Neuroblastomas: New Insights for the Healthcare Professional: 2013 Edition

Neuroblastomas: New Insights for the Healthcare Professional: 2013 Edition
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2013-07-22
  • Total pages :143
  • ISBN : 9781481654548
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Summary : Neuroblastomas: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Additional Research. The editors have built Neuroblastomas: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Additional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Neuroblastomas: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

CBD Oil for Neuroblastoma

CBD Oil for Neuroblastoma
  • Author : Dr Emmy Akins
  • Publisher :Unknown
  • Release Date :2020-04-16
  • Total pages :32
  • ISBN : 9798637680023
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Summary : Neuroblastoma is a rare type of cancerous tumor that's most commonly diagnosed in infants and children under age 5. It is extremely rare in people over age 10. Neuroblastoma is the most common type of solid cancerous tumor, other than brain tumors, found in children.About 800 new cases of neuroblastoma are diagnosed each year in the United States, according to the American Cancer Society. It accounts for about 6% of all childhood cancers, and it's the most common tumor in infants.

Neuroblastoma

Neuroblastoma
  • Author : Chandrika Gowda
  • Publisher :Unknown
  • Release Date :2017-10-25
  • Total pages :168
  • ISBN : 9789535135838
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Summary : Neuroblastoma (NBL) is the most common extracranial solid tumor of childhood, with about 700 new cases of neuroblastoma seen each year in the United States. The 5-year survival rate for children with high-risk NBL is only 50-60%, and this survival rate has not improved over the last 10 years. High-risk patients receive multimodality treatment, including chemotherapy, surgery, radiation therapy, biologic therapy and immunotherapy, all of which are associated with significant morbidity. Recent years have seen many advances in treatment of neuroblastoma, including therapeutic MIBG, immunotherapy, and personalized targeted therapy based on the genetic alterations seen in the tumor. The primary objective of this book is to provide the readers with a comprehensive review of neuroblastoma, from clinical aspects and the currently available treatment to recent advancements and future directions in the field of NBL treatment. The topics and chapters have been compiled keeping in mind a diverse group of readers in different areas of specialty such as pediatric oncology, surgery, radiation oncology, and immunology, as well as physician scientists and basic researchers working in the field of neuroblastoma.

Ashcraft's Pediatric Surgery E-Book

Ashcraft's Pediatric Surgery E-Book
  • Author : George W. Holcomb,J. Patrick Murphy,Daniel J Ostlie
  • Publisher :Unknown
  • Release Date :2014-01-31
  • Total pages :992
  • ISBN : 9780323187367
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Summary : Acclaimed for its unsurpassed readability and manageable scope, Ashcraft’s Pediatric Surgery presents authoritative, practical guidance on treating the entire range of general surgical and urological problems in infants, children, and adolescents. State-of-the-art, expert coverage equips you to implement all the latest approaches and achieve optimal outcomes for all of your patients. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Make the most effective use of today’s best open and minimally invasive techniques, including single-site umbilical laparoscopic surgery, with guidance from internationally recognized experts in the field. Focus on evidence-based treatments and outcomes to apply today’s best practices. Stay current with timely topics thanks to brand-new chapters on Choledochal Cyst and Gallbladder Disease, Tissue Engineering, and Ethics in Pediatric Surgery, plus comprehensive updates throughout. Hone and expand your surgical skills by watching videos of minimally invasive procedures for recto urethral fistula, biliary atresia, laparoscopic splenectomy, uterine horn, and more. Grasp the visual nuances of surgery from over 1,000 images depicting today’s best surgical practices.

Urologic Surgical Pathology E-Book

Urologic Surgical Pathology E-Book
  • Author : Liang Cheng,David G. Bostwick
  • Publisher :Unknown
  • Release Date :2014-01-24
  • Total pages :1040
  • ISBN : 9780323086196
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Summary : With sweeping revisions throughout, the new edition of Urologic Surgical Pathology equips you to accurately diagnose specimens of the entire urinary tract and male reproductive system plus the adrenal glands. Comprehensive in scope, this title begins with a look at normal anatomy and histology for each organ system...followed by discussions of the pathology of congenital anomalies, inflammations, non-neoplastic diseases and neoplasia. Practical guidance in daily urological pathology sign-out and the latest recommended diagnostic approaches — with an emphasis on clinicopathologic and radiographic-pathologic correlations — makes this a true diagnostic decision-making medical reference. A consistent format enables you to locate critical information quickly, and more than 1600 high-quality illustrations — most in full color — make diagnosis even easier. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Rely on the practice-proven experience of today’s authorities to identify and diagnose with confidence. Confirm your diagnostic suspicions by comparing your findings to more than 1600 color images and color graphics. Quickly locate the specific information you need through an abundance of tables, diagrams and flowcharts; boxed lists of types and causes of diseases; differential diagnosis; characteristic features of diseases; complications; classifications; and staging. Stay current with the latest information on: differential diagnosis for all tumor types encountered in urological surgical pathology practice; urologic tumor specimen handling and reporting guidelines; new entities and updated classification schemes; and newer immunohistochemical and genetic diagnostic methods. Develop targeted therapy specific to a particular patient’s problem based on key molecular aspects of disease, especially in relevance to targeted therapy/personalized medicine. Provide the clinician with the most accurate diagnostic and prognostic indicators, by incorporating the latest classification and staging systems in your reports. Deepen your understanding of new diagnostic biomarkers and their utility in differential diagnosis.

P14ARF Suppresses Malignant Properties of Neuroblastoma Cells, and Its Activation is Impaired in Neuroblastoma Subtypes

P14ARF Suppresses Malignant Properties of Neuroblastoma Cells, and Its Activation is Impaired in Neuroblastoma Subtypes
  • Author : Daniel Dreidax
  • Publisher :Unknown
  • Release Date :2011
  • Total pages :118
  • ISBN : OCLC:1185829338
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Summary :

Color Atlas of Pediatric Pathology

Color Atlas of Pediatric Pathology
  • Author : Aliya N. Husain, MD,J. Thomas Stocker, MD
  • Publisher :Unknown
  • Release Date :2011-02-25
  • Total pages :486
  • ISBN : 9781935281405
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Summary : Pediatric pathology has been a recognized sup-specialty of pathology for almost two decades. Today pathology training programs are required to provide education in pediatric pathology. In addition to pediatric pathology specialists, many general and community-based pathologists regularly handle pediatric specimens. A working knowledge of current pediatric pathology is essential for appropriate handling of these cases. The Color Atlas of Pediatric Pathology covers the broad range of pediatric diseases that a pathologist will likely encounter and is written by well-known leaders in this field. Coverage includes both frequent and less commonly seen cases, and each discussion presents a concise summary of the salient features of the disease along with expertly selected, high-quality color images. The Color Atlas of Pediatric Pathology is a practical working resource for every pathologist who sees pediatric cases as well as the pathology trainee. The atlas features approximately 1,100 high-quality images as well as important staging and prognostic (including molecular) parameters. Features of the Color Atlas of Pediatric Pathology include: Comprehensive coverage of pediatric surgical and autopsy pathology Each chapter is presented by a recognized expert Practical presentation: concise text highlights diagnostic features making the atlas an outstanding resource for the practitioner Illustrated throughout with approximately 1,100 full-color images

Leibel and Phillips Textbook of Radiation Oncology - E-Book

Leibel and Phillips Textbook of Radiation Oncology - E-Book
  • Author : Richard Hoppe,Theodore L. Phillips,Mack Roach
  • Publisher :Unknown
  • Release Date :2010-09-09
  • Total pages :1664
  • ISBN : 9781437737752
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Summary : Stay on top of the latest scientific and therapeutic advances with the new edition of Leibel and Phillips Textbook of Radiation Oncology. Dr. Theodore L. Phillips, in collaboration with two new authors, Drs. Richard Hoppe and Mack Roach, offers a multidisciplinary look at the presentation of uniform treatment philosophies for cancer patients emphasizing the "treat for cure" philosophy. You can also explore the implementation of new imaging techniques to locate and treat tumors, new molecularly targeted therapies, and new types of treatment delivery. Supplement your reading with online access to the complete contents of the book, a downloadable image library, and more at expertconsult.com. Gather step-by-step techniques for assessing and implementing radiotherapeutic options with this comprehensive, full-color, clinically oriented text. Review the basic principles behind the selection and application of radiation as a treatment modality, including radiobiology, radiation physics, immobilization and simulation, high dose rate, and more. Use new imaging techniques to anatomically locate tumors before and during treatment. Apply multidisciplinary treatments with advice from experts in medical, surgical, and radiation oncology. Explore new treatment options such as proton therapy, which can facilitate precise tumor-targeting and reduce damage to healthy tissue and organs. Stay on the edge of technology with new chapters on IGRT, DNA damage and repair, and molecularly targeted therapies.

Oncology of Infancy and Childhood E-Book

Oncology of Infancy and Childhood E-Book
  • Author : Stuart H. Orkin,David E. Fisher,A. Thomas Look,Samuel Lux,David Ginsburg,David G. Nathan
  • Publisher :Unknown
  • Release Date :2009-06-09
  • Total pages :1392
  • ISBN : 9781437721386
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Summary : To address the growing complexities of childhood cancer, Nathan and Oski’s Hematology and Oncology of Infancy and Childhood has now been separated into two distinct volumes. With this volume devoted strictly to pediatric oncology, and another to pediatric hematology, you will be on the cutting edge of these two fields. This exciting new, full-color reference provides you with the most comprehensive, authoritative, up-to-date information for diagnosing and treating children with cancer. It brings together the pathophysiology of disease with detailed clinical guidance on diagnosis and management for the full range of childhood cancers, including aspects important in optimal supportive care. Written by the leading names in pediatric oncology, this resource is an essential tool for all who care for pediatric cancer patients. Offers comprehensive coverage of all pediatric cancers, including less common tumors, making this the most complete guide to pediatric cancer. Covers emerging research developments in cancer biology and therapeutics, both globally and in specific pediatric tumors. Includes a section on supportive care in pediatric oncology, written by authors who represent the critical subdisciplines involved in this important aspect of pediatric oncology. Uses many boxes, graphs, and tables to highlight complex clinical diagnostic and management guidelines. Presents a full-color design that includes clear illustrative examples of the relevant pathology and clinical issues, for quick access to the answers you need. Incorporates the codified WHO classification for all lymphomas and leukemias.

Childhood Leukemia and Cancer, An Issue of Pediatric Clinics, E-Book

Childhood Leukemia and Cancer, An Issue of Pediatric Clinics, E-Book
  • Author : Yaddanapudi Ravindranath
  • Publisher :Unknown
  • Release Date :2014-12-26
  • Total pages :353
  • ISBN : 9780323354660
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Summary : This issue concentrates on the current evidence and the collected experience of pediatric oncologists who care for cancer patients. The individual articles will provide the general pediatrician with a comprehensive primer on diagnosing and managing various types of cancers in the child with cancer. A cancer diagnosis is no longer a death sentence, so management and monitoring is very important and covered in every article.

Rosai and Ackerman's Surgical Pathology E-Book

Rosai and Ackerman's Surgical Pathology E-Book
  • Author : Juan Rosai
  • Publisher :Unknown
  • Release Date :2011-06-20
  • Total pages :2892
  • ISBN : 9780323088046
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Summary : Rosai and Ackerman’s Surgical Pathology delivers the authoritative guidance you need to overcome virtually any challenge in surgical pathology. Recognized globally for his unmatched expertise, preeminent specialist Juan Rosai, MD brings you state-of-the-art coverage of the latest advancements in immunohistochemistry, genetics, molecular biology, prognostic/predictive markers, and much more - equipping you to effectively and efficiently diagnose the complete range of neoplastic and non-neoplastic entities. Efficiently review the clinical presentation, gross and microscopic features, ultrastructural and immunohistochemical findings, differential diagnosis, therapy, and prognosis for virtually every pathologic entity. Compare your findings to more than 3,300 outstanding illustrations that capture the characteristic presentation of every type of lesion. Avoid diagnostic pitfalls using Dr. Rosai's expert observations on what to look for, what to be careful about, and which presentations can be misleading. Find quick answers on tumor staging, quality control procedures, and the handling of gross specimens through valuable appendices. Make optimal use of all the very latest advances including our increased understanding of the genetic basis of inherited and acquired disease, the newest molecular genetic and immunohistochemical techniques, and the most recent WHO disease classification schemes.