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New Techniques for Management of ‘Inoperable’ Gliomas

New Techniques for Management of ‘Inoperable’ Gliomas
  • Author : Michael E. Sughrue,Isaac Yang
  • Publisher :Unknown
  • Release Date :2019-08-03
  • Total pages :256
  • ISBN : 9780128136348
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Summary : New Techniques for Management of 'Inoperable' Gliomas radically challenges the assumption that certain gliomas cannot be removed with modern techniques, contesting stereotypical thinking and establishing new paradigms in the field. Gliomas are primary brain tumors which are often fatal. Recent data has demonstrated that despite the fact that surgery cannot cure gliomas, patient survival is substantially improved by removing as much of the tumor as possible. This fact has raised the imperative that neurologists try to improve techniques to bring surgical resection to as many patients as possible. This book brings new insights and technologies to the forefront, giving hope to patients. Provides the first comprehensive book to discuss techniques for removing gliomas that are traditionally deemed ‘inoperable’ Presents a great reference tool that challenges stereotypical thinking by offering techniques by innovative surgeons Includes chapters that are organized by different glioma types and surgery/techniques

The Glioma Book

The Glioma Book
  • Author : Michael E. Sughrue
  • Publisher :Unknown
  • Release Date :2019-10-25
  • Total pages :350
  • ISBN : 9781626234451
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Summary : A unique resource on glioma leverages advances and firsthand insights to enact meaningful change Glioblastoma (GBM) or glioma is an extremely aggressive and malignant brain tumor, with cell infiltration, rapid invasion, and a high frequency of relapse. The Glioma Book by neurosurgeon Michael Sughrue is a highly personal book — a culmination of two years of writing and more than 1,000 surgeries. It presents a unique viewpoint with the potential to transform the traditional paradigm that too often informs treatment of this universally fatal brain tumor. The book reinterprets the role of the cerebrum and sub-cortex, leverages scientific advances to improve cytoreduction and reduce neurological deficits, and challenges the myth of the "inoperable" glioma. This is the first step-by-step technical guide focused on aggressively resecting different types of gliomas. The book is logically organized, starting with a foundation of fundamental knowledge, then progressing to practical applications. Chapters focus on the skills necessary to perform glioma surgery, specific techniques, and systematic approaches to gliomas in different brain regions. Numerous case examples illuminate concepts introduced earlier in the book and explain how to perform these procedures About 30 high quality videos posted online provide insightful procedural guidance The role of connectomic imaging in visualizing the cerebrum, and other innovative techniques including awake brain mapping and diffusion tensor tractography Neurosurgeons who embrace the concepts in this book will realize they can change the glioma treatment paradigm. Continually improving techniques and viewing a glioma diagnosis as a battle for a patient's life, rather than an exercise in inevitable failure can impart progress in treating this devastating disease.

Gliomas: New Insights for the Healthcare Professional: 2011 Edition

Gliomas: New Insights for the Healthcare Professional: 2011 Edition
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2012-01-09
  • Total pages :175
  • ISBN : 9781464901416
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Summary : Gliomas: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Gliomas. The editors have built Gliomas: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Gliomas in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Gliomas: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Novel Therapeutic Concepts in Targeting Glioma

Novel Therapeutic Concepts in Targeting Glioma
  • Author : Faris Farassati
  • Publisher :Unknown
  • Release Date :2012-04-04
  • Total pages :308
  • ISBN : 9789535104919
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Summary : Novel Therapeutic Concepts for Targeting Glioma offers a comprehensive collection of current information and the upcoming possibilities for designing new therapies for Glioma by an array of experts ranging from Cell Biologists to Oncologists and Neurosurgeons. A variety of topics cover therapeutic strategies based on Cell Signaling, Gene Therapy, Drug Therapy and Surgical methods providing the reader with a unique opportunity to expand and advance his knowledge of the field.

Adult CNS Radiation Oncology

Adult CNS Radiation Oncology
  • Author : Eric L. Chang,Paul D. Brown,Simon S. Lo,Arjun Sahgal,John H. Suh
  • Publisher :Unknown
  • Release Date :2018-07-27
  • Total pages :766
  • ISBN : 9783319428789
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Summary : This book elucidates the radiation therapy protocols and procedures for the management of adult patients presenting with primary benign and malignant central nervous system tumors. With the development of new treatment strategies and rapid advancement of radiation technology, it is crucial for radiation oncologists to maintain and refine their knowledge and skills. Dedicated exclusively to adult CNS radiation oncology, this textbook explores CNS tumors ranging from the common to the esoteric as well as secondary cancers of metastatic origin. The first half of the book is organized anatomically: tumors of the brain, spinal cord, leptomeninges, optic pathway, ocular choroid, and skull base. The second half covers primary CNS lymphoma, rare CNS tumors, metastatic brain disease, vascular conditions of the CNS, radiation-associated complications, and radiation modalities. Each chapter provides guidance on treatment field design, target delineation, and normal critical structure tolerance constraints in the context of the disease being treated. Learning objectives, case studies, and Maintenance of Certification Self-Assessment Continuing Medical Education-style questions and answers are incorporated throughout the book. This is an ideal guide for radiation oncologists, residents, and fellows, but medical students may also find value in the text.

Glioma

Glioma
  • Author : Ibrahim Omerhodzic,Kenan Arnautovic
  • Publisher :Unknown
  • Release Date :2019-01-16
  • Total pages :258
  • ISBN : 9781789849530
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Summary : The past three decades have been marked with huge enthusiasm from scientists and professionals in an effort to find a cure for glioma disease. Methods to confirm the kinds and grades of glioma have taken a path from classical macro- to microscopic pathohystological confirmation of tumors, through morphological-histological, molecular, and genetic diagnosis. Surgically, progress was made possible with the development and use of technological aids, for example neuronavigation, cortical mapping, electrocorticography, neuromonitoring, functional and intraoperative MRI, magnetoencephalography, etc. Great hope was placed on the extension of tumor resection and popular supratotal resection. Significant progress has been made generally in glioma treatment with the use of modern radiotherapy and new chemotherapeutics. What do we want to see for the future? By way of stem cells, a specific medicine will be produced, individualized for the particular patient, and by using a microcapsule it will be implanted into the brain zone affected by the tumor by way of robot surgery and injection needle. This is not at all an unrealistic expectation in the next decade or two.

Modern Management of High Grade Glioma, Part I, An Issue of Neurosurgery Clinics - E-Book

Modern Management of High Grade Glioma, Part I, An Issue of Neurosurgery Clinics - E-Book
  • Author : Isaac Yang,Seunggu J. Han
  • Publisher :Unknown
  • Release Date :2012-04-28
  • Total pages :174
  • ISBN : 9781455744183
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Summary : Standard therapy for high grade glioma is a topic that is evolving, timely, and relevant. Guest Editors Isaac Yang, MD and Seunggu Han, MD have assembled a group of experts to highlight the latest updates on various forms of management of high grade glioma. Some of the articles included in this issue focus on Extent of Resection for Glioblastoma; Role of adjuvant radiation therapy; Survival benefit of the Temozolomide protocol; Alternative chemotherapeutic agents; The role of avastin; Radiology; Pseuodprogression and Treatment effect; Pathology; Medical Management; Management of insular gliomas; Use of motor mapping; GBM treatment with clinical trials for surgical resection; Clinical trials with immunotherapy; Clinical trials for small molecule inhibitors; Future role of CED for GBM treatment; Application of a vault nanoparticle therapy for GBM therapy; Management of high grade gliomas in pediatric populations; Targeting Glioma Stem Like Cells with a focus on CD 133; and Potential Role for STAT3 inhibitors in glioblastoma.

Comprehensive Overview of Modern Surgical Approaches to Intrinsic Brain Tumors

Comprehensive Overview of Modern Surgical Approaches to Intrinsic Brain Tumors
  • Author : Kaisorn Chaichana,Alfredo Quinones-Hinojosa
  • Publisher :Unknown
  • Release Date :2019-02-28
  • Total pages :506
  • ISBN : 9780128117842
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Summary : Comprehensive Overview of Modern Surgical Approaches to Intrinsic Brain Tumors addresses limitations in the scientific literature by focusing primarily on surgical approaches to various intrinsic neoplasms using diagrams and step-by-step instructions. It provides the advantages and disadvantages of these approaches, controversies, and technical considerations and discusses topics such as anatomy, pathology and animal models, imaging, open brain tumor approaches and minimally invasive approaches. Additionally, it discusses controversial treatments and the pros and cons of each. This book is a valuable source for medical students, neurosurgeons and any healthcare provider who has an interest in brain tumors and techniques to treat them. Provides a comprehensive review of different approaches, explaining them step-by- step Includes diagrams that show surgical approaches Presents the advantages and disadvantages of each approach to aid in decision-making

Diffuse Low-Grade Gliomas in Adults

Diffuse Low-Grade Gliomas in Adults
  • Author : Hugues Duffau
  • Publisher :Unknown
  • Release Date :2013-03-19
  • Total pages :502
  • ISBN : 9781447122135
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Summary : This book presents the latest research pertaining to the diagnosis, therapy and management of diffuse low-grade gliomas (DLGG) in adults, with a particular focus on the path towards individualised therapy for this kind of tumour. Recent research on the natural history of DLGGs and their interaction with the brain has led to new diagnostic and therapeutic strategies which increase survival and quality of life of the patient, and these methods are described in this book.

Management of Adult Glioma in Nursing Practice

Management of Adult Glioma in Nursing Practice
  • Author : Ingela Oberg
  • Publisher :Unknown
  • Release Date :2019-01-04
  • Total pages :314
  • ISBN : 9783319767475
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Summary : This contributed book focuses on the nursing care and considerations for the most common type of malignant brain tumours – gliomas, out of the 150 different types of brain tumours . The reader will gain specialist knowledge in understanding the disease trajectory of malignant gliomas and gain a deeper understanding of the presenting symptoms and varying treatment options of this highly malignant tumour. High grade malignant gliomas impact significantly on prognosis, with an average life expectancy of 18-24 months from diagnosis, given maximum treatment options including surgery, chemotherapy and radiotherapy. This book takes you through all current treatment options with their associated risks and intended benefits. Brain tumours affect not just the patient, but their family and carers too and this important aspect of holistic nursing care is not to be overlooked. This book encompasses first hand experiences of both a brain tumour patient living with a glioma and aspects from a carer. The structure of this book follows a typical patient pathway from presenting signs / symptoms through to MDT (multidisciplinary team) discussions to surgical techniques and radiological investigations, right through to chemotherapy, radiotherapy and palliative care including end of life care. It provides a distinct overview of the holistic needs spectrum encompassing the entire patient journey and equips the reader with learning objectives set at every chapter. Although this book is primarily aimed at Nurses working at ward level within neuro-oncology, this book is also intended to benefit professionals new to the field of specialist nursing – in particular those working with adult brain tumours and neuro-oncology.

Handbook of Clinical Neurology

Handbook of Clinical Neurology
  • Author : P. J. Vinken,G. W. Bruyn
  • Publisher :Unknown
  • Release Date :1974
  • Total pages :229
  • ISBN : CHI:14137458
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Summary :

Tumours of the Brain and Skull

Tumours of the Brain and Skull
  • Author : P. J. Vinken,G. W. Bruyn
  • Publisher :Unknown
  • Release Date :1975
  • Total pages :582
  • ISBN : PSU:32239000032678
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Summary :

Intracranial Gliomas Part II - Adjuvant Therapy

Intracranial Gliomas Part II - Adjuvant Therapy
  • Author : M.F. Chernov,Y. Muragaki,S. Kesari,I.E. McCutcheon
  • Publisher :Unknown
  • Release Date :2018-01-25
  • Total pages :252
  • ISBN : 9783318060591
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Summary : Treatment of patients with intracranial gliomas, especially high-grade neoplasms, usually requires postoperative adjuvant therapy. Significant progress in the understanding of tumor biology, technological advances in irradiation delivery, and development of novel antitumor drugs have led to an expansion of the therapeutic arsenal in neuro-oncology. This publication provides a unique review of the various options for adjuvant therapy. Special emphasis is on current evidence-based treatment standards and guidelines, and on perspectives of further improvement in long-term outcomes. Chapters review the histopathological and molecular features of gliomas and describe basic principles and clinical results of fractionated radiotherapy, stereotactic radiosurgery, brachytherapy, use of radiosensitizers, systemic chemotherapy and antiangiogenic therapy. Particular attention is paid to treatment of pediatric patients and to physical and psychological rehabilitation and supportive care at the end of life. This book and its accompanying volumes are mainly directed at neuro-oncologists, radiation oncologists, and other clinicians treating patients with brain tumors.

Abstracts and Descriptions of Contributions to the Scientific Program

Abstracts and Descriptions of Contributions to the Scientific Program
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :1961
  • Total pages :181
  • ISBN : NWU:35558000723706
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Summary :

Brain Tumors

Brain Tumors
  • Author : Amit Agrawal,Luis Rafael Moscote-Salazar
  • Publisher :Unknown
  • Release Date :2018-08-22
  • Total pages :248
  • ISBN : 9781789235562
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Summary : We all know that the field of neuro-oncology is heterogeneous and under continuous development with the addition of new knowledge and information on a regular basis. The present book "Brain Tumor - An Update" is an attempt to share the personal experiences of experts who are involved in neuro-oncology-related research. Through this book, the authors share their experiences and provide details about the pathophysiology, neuroimaging approaches, and management options, and how to go about decision-making in patients with brain tumors. We hope that the valuable contributions from the authors shall facilitate understanding about brain tumors. I am grateful to all the authors who have contributed their tremendous expertise, and I would like to acknowledge the outstanding support of Ms. Danijela Sakic, Author Service Manager, IntechOpen Science, who collaborated tirelessly in crafting this book.

Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy

Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy
  • Author : Herbert B. Newton
  • Publisher :Unknown
  • Release Date :2018-03-28
  • Total pages :848
  • ISBN : 9780128121016
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Summary : Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy, Second Edition, provides a comprehensive overview of the molecular methodologies in the neuro-oncology field. There have been profound changes in the landscape of approaches to brain tumor therapy since the first edition—mainly in the areas of molecular biology and molecular therapeutics, as well as in the maturation of immunotherapy approaches (e.g., vaccines). This updated edition has a new, primary focus on multidisciplinary molecular methods, and is broadened to include the latest cutting-edge molecular biology, therapeutics, immunobiology and immunotherapy approaches. As the first comprehensive book to address the molecular research into these concepts, users will find it to be an invaluable resource on the topics discussed. Provides the most up-to-date information regarding conventional forms of cytotoxic chemotherapy, as well as the basic science and clinical application of molecular therapeutics for the treatment of brain tumors Broadly appeals to anyone interested in neuro-oncology and the treatment of brain tumors Features updated chapters on molecular biology, molecular therapeutics, maturation of immunotherapy approaches, and a focus on multidisciplinary molecular methods Includes a new section on the basic science of immunology, as well as thorough updates on the use of vaccine technology and immunotherapy for the treatment of brain tumors

Radiation Injury to the Nervous System

Radiation Injury to the Nervous System
  • Author : Philip H. Gutin,Steven A. Leibel,Glenn E. Sheline
  • Publisher :Unknown
  • Release Date :1991
  • Total pages :482
  • ISBN : UOM:39015021905255
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Summary : The experimental results & clinical experiences of tolerance of nervous system to ionizing radiation/normal tissue/etc.

Intracranial Gliomas Part III - Innovative Treatment Modalities

Intracranial Gliomas Part III - Innovative Treatment Modalities
  • Author : M.F. Chernov,Y. Muragaki,S. Kesari,I.E. McCutcheon
  • Publisher :Unknown
  • Release Date :2018-07-10
  • Total pages :222
  • ISBN : 9783318060638
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Summary : At present most intracranial gliomas are considered incurable with current treatment strategies, and the search for new modalities that may effectively control tumor growth continues. The chapters in this volume describe basic principles and therapeutic possibilities of several innovative techniques, including photodynamic therapy, laser-induced interstitial thermotherapy, stereotactic cryodestruction, high-intensity focused ultrasound ablation, boron neutron capture therapy, proton and carbon ion irradiation, targeted therapy, immunotherapy, gene therapy, local chemotherapy, and alternating electric fields therapy. Potential applications of extracellular vesicles and nanotechnology for management of gliomas are highlighted as well. Many of these methods have already demonstrated antitumor efficacy in clinical testing, whereas others are still under development. The materials presented in this book are mainly directed at clinicians treating patients with brain tumors, as well as clinical and basic researchers working in the field of neuro-oncology.

New Approaches to the Management of Primary and Secondary CNS Tumors

New Approaches to the Management of Primary and Secondary CNS Tumors
  • Author : Lee Roy Morgan
  • Publisher :Unknown
  • Release Date :2017-03-23
  • Total pages :214
  • ISBN : 9789535130512
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Summary : Several new concepts are reviewed and discussed in this book and allude to the transport of drugs bound to red blood cells into the vascular blood-brain barrier and into cancer cells. Such a transport system is novel and of potential therapeutic potential. It is the goal of this book to provide information and data that will be useful for others to develop new approaches for the management of CNS malignancies.

The Duke Glioma Handbook

The Duke Glioma Handbook
  • Author : Allan H. Friedman
  • Publisher :Unknown
  • Release Date :2016-03-31
  • Total pages :220
  • ISBN : 9781107065970
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Summary : Provides a summary of glioma biology, genetics and management, based on the world-leading Duke University Preston Robert Tisch Brain Tumor Center program.

Walter and Miller's Textbook of Radiotherapy E-book

Walter and Miller's Textbook of Radiotherapy E-book
  • Author : Paul R Symonds,Charles Deehan,Catherine Meredith,John A Mills
  • Publisher :Unknown
  • Release Date :2012-06-29
  • Total pages :704
  • ISBN : 9780702046629
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Summary : A comprehensive textbook of radiotherapy and related radiation physics and oncology for use by all those concerned with the uses of radiation and cytotoxic drugs in the treatment of patients with malignant disease. Walter & Miller's Textbook of Radiotherapy has become the core text for therapeutic radiography students and an important introductory text for trainee radiologists and clinical physicists. The book is divided into two parts: the first covers underlying principles of physics, and the second is a systematic review by tumour site concentrating on the role of radiotherapy in the treatment of malignant disease and setting its use in context with chemotherapy and surgery. The 7th edition continues the tradition of bringing the physics and clinical application of radiation for therapy together at entry level and is completely revised to take into account the huge technological advances in radiotherapy treatment since publication of the previous edition. *Imaging is now an essential part of radiotherapy, relevant for both the treatment and preparation of a patient's treatment. Radionuclide imaging and X-ray imaging have been expanded to MRI and PET, along with some use of ultrasound. *Treatment planning dose prediction - the basis and application of modern computational calculations are explained for modern treatment delivery systems. The role of the algorithm for dose prediction is central to ensure speedy and accurate calculations for treatment. *Quality Control *Quality Systems The book is supported by Evolve electronic resources: sample plans, additional diagnostic images and clinical photographs.