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Peptide Applications in Biomedicine, Biotechnology and Bioengineering

Peptide Applications in Biomedicine, Biotechnology and Bioengineering
  • Author : Sotirios Koutsopoulos
  • Publisher :Unknown
  • Release Date :2017-11-16
  • Total pages :656
  • ISBN : 9780081007426
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Summary : Peptide Applications in Biomedicine, Biotechnology and Bioengineering summarizes the current knowledge on peptide applications in biomedicine, biotechnology and bioengineering. After a general introduction to peptides, the book addresses the many applications of peptides in biomedicine and medical technology. Next, the text focuses on peptide applications in biotechnology and bioengineering and reviews of peptide applications in nanotechnology. This book is a valuable resource for biomaterial scientists, polymer scientists, bioengineers, mechanical engineers, synthetic chemists, medical doctors and biologists. Presents a self-contained work for the field of biomedical peptides Summarizes the current knowledge on peptides in biomedicine, biotechnology and bioengineering Covers current and potential applications of biomedical peptides

Radiopharmaceutical Chemistry

Radiopharmaceutical Chemistry
  • Author : Jason S. Lewis,Albert D. Windhorst,Brian M. Zeglis
  • Publisher :Unknown
  • Release Date :2019-04-02
  • Total pages :651
  • ISBN : 9783319989471
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Summary : This book is a comprehensive guide to radiopharmaceutical chemistry. The stunning clinical successes of nuclear imaging and targeted radiotherapy have resulted in rapid growth in the field of radiopharmaceutical chemistry, an essential component of nuclear medicine and radiology. However, at this point, interest in the field outpaces the academic and educational infrastructure needed to train radiopharmaceutical chemists. For example, the vast majority of texts that address radiopharmaceutical chemistry do so only peripherally, focusing instead on nuclear chemistry (i.e. nuclear reactions in reactors), heavy element radiochemistry (i.e. the decomposition of radioactive waste), or solely on the clinical applications of radiopharmaceuticals (e.g. the use of PET tracers in oncology). This text fills that gap by focusing on the chemistry of radiopharmaceuticals, with key coverage of how that knowledge translates to the development of diagnostic and therapeutic radiopharmaceuticals for the clinic. The text is divided into three overarching sections: First Principles, Radiochemistry, and Special Topics. The first is a general overview covering fundamental and broad issues like “The Production of Radionuclides” and “Basics of Radiochemistry”. The second section is the main focus of the book. In this section, each chapter’s author will delve much deeper into the subject matter, covering both well established and state-of-the-art techniques in radiopharmaceutical chemistry. This section will be divided according to radionuclide and will include chapters on radiolabeling methods using all of the common nuclides employed in radiopharmaceuticals, including four chapters on the ubiquitously used fluorine-18 and a “Best of the Rest” chapter to cover emerging radionuclides. Finally, the third section of the book is dedicated to special topics with important information for radiochemists, including “Bioconjugation Methods,” “Click Chemistry in Radiochemistry”, and “Radiochemical Instrumentation.” This is an ideal educational guide for nuclear medicine physicians, radiologists, and radiopharmaceutical chemists, as well as residents and trainees in all of these areas.

Peptide Synthesis

Peptide Synthesis
  • Author : Jaya Varkey
  • Publisher :Unknown
  • Release Date :2019-12-18
  • Total pages :118
  • ISBN : 9781839682575
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Summary : Peptide synthesis includes an array of techniques and procedures that enable the preparation of materials ranging from small peptides to large proteins. Many synthetic peptides have commercial and pharmaceutical applications, however, the synthesis of these peptides is a difficult task. This book addresses the common problems relating to the synthesis and applications of synthetic peptides. It discusses novel methods for the efficient synthesis of long chain and difficult peptide sequences and presents detailed analysis of various aspects of solid phase peptide synthesis. It also includes a section on antimicrobial peptides.

Natural Bio-active Compounds

Natural Bio-active Compounds
  • Author : Mohd Sayeed Akhtar,Mallappa Kumara Swamy
  • Publisher :Unknown
  • Release Date :2019-09-28
  • Total pages :330
  • ISBN : 9789811374388
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Summary : Natural bioactive compounds have become an integral part of plant-microbe interactions geared toward adaptation to environmental changes. They regulate symbiosis, induce seed germination, and manifest allelopathic effects, i.e., they inhibit the growth of competing plant species in their vicinity. In addition, the use of natural bioactive compounds and their products is considered to be suitable and safe in e.g. alternative medicine. Thus, there is an unprecedented need to meet the increasing demand for plant secondary metabolites in the flavor and fragrance, food, and pharmaceutical industries. However, it is difficult to obtain a constant quantity of compounds from the cultivated plants, as their yield fluctuates due to several factors including genotypic variations, the geography, edaphic conditions, harvesting and processing methods. Yet familiarity with these substances and the exploration of various approaches could open new avenues in their production. This book describes the basis of bioactive plant compounds, their mechanisms and molecular actions with regard to various human diseases, and their applications in the drug, cosmetic and herbal industries. Accordingly, it offers a valuable resource for students, educators, researchers, and healthcare experts involved in agronomy, ecology, crop science, molecular biology, stress physiology, and natural products.

Artificial Protein and Peptide Nanofibers

Artificial Protein and Peptide Nanofibers
  • Author : Gang Wei,Sangamesh G. Kum bar
  • Publisher :Unknown
  • Release Date :2020-07-28
  • Total pages :502
  • ISBN : 9780081028513
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Summary : Artificial Protein and Peptide Nanofibers: Design, Fabrication, Characterization, and Applications provides comprehensive knowledge of the preparation, modification and applications of protein and peptide nanofibers. The book reviews the synthesis and strategies necessary to create protein and peptide nanofibers, such as self-assembly (including supramolecular assembly), electrospinning, template synthesis, and enzymatic synthesis. Then, the key chemical modification and molecular design methods are highlighted that can be utilized to improve the bio-functions of these synthetic fibers. Finally, fabrication methods for key applications, such as sensing, drug delivery, imaging, tissue engineering and electronic devices are reviewed. This book will be an ideal resource for those working in materials science, polymer science, chemical engineering, nanotechnology and biomedicine. Reviews key chemical modification and molecular design methods to improve the bio-functions of synthetic peptide and protein nanofibers Discusses the most important synthesis strategies, including supramolecular assembly, electrospinning, template synthesis and enzymatic synthesis Provides information on fabrication of nanofibers for key applications such as sensing, imaging, drug delivery and tissue engineering

Peptides and Peptide-based Biomaterials and their Biomedical Applications

Peptides and Peptide-based Biomaterials and their Biomedical Applications
  • Author : Anwar Sunna,Andrew Care,Peter L. Bergquist
  • Publisher :Unknown
  • Release Date :2017-10-26
  • Total pages :300
  • ISBN : 9783319660950
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Summary : Solid-binding peptides have been used increasingly as molecular building blocks in nanobiotechnology as they can direct the assembly and functionalisation of a diverse range of materials and have the ability to regulate the synthesis of nanoparticles and complex nanostructures. Nanostructured materials such as β-sheet fibril-forming peptides and α-helical coiled coil systems have displayed many useful properties including stimulus-responsiveness, modularity and multi-functionality, providing potential technological applications in tissue engineering, antimicrobials, drug delivery and nanoscale electronics. The current situation with respect to self-assembling peptides and bioactive matrices for regenerative medicine are reviewed, as well as peptide-target modeling and an examination of future prospects for peptides in these areas.

Biomedical Applications of Functionalized Nanomaterials

Biomedical Applications of Functionalized Nanomaterials
  • Author : Bruno Sarmento,Jose Das Neves
  • Publisher :Unknown
  • Release Date :2018-03-01
  • Total pages :778
  • ISBN : 9780323508797
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Summary : Biomedical Applications of Functionalized Nanomaterials: Concepts, Development and Clinical Translation presents a concise overview of the most promising nanomaterials functionalized with ligands for biomedical applications. The first section focuses on current strategies for identifying biological targets and screening of ligand to optimize anchoring to nanomaterials, providing the foundation for the remaining parts. Section Two covers specific applications of functionalized nanomaterials in therapy and diagnostics, highlighting current practice and addressing major challenges, in particular, case studies of successfully developed and marketed functionalized nanomaterials. The final section focuses on regulatory issues and clinical translation, providing a legal framework for their use in biomedicine. This book is an important reference source for worldwide drug and medical devices policymakers, biomaterials scientists and regulatory bodies. Provides an overview of the methodologies for biological target identification and ligand screening Includes case studies showing the development of functionalized nanomaterials and their biomedical applications Highlights the importance of functionalized nanomaterials for drug delivery, diagnostics and regenerative medicine applications

Biomedical Engineering Handbook 2

Biomedical Engineering Handbook 2
  • Author : Joseph D. Bronzino
  • Publisher :Unknown
  • Release Date :2000-02-15
  • Total pages :229
  • ISBN : 354066808X
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Summary :

Biopolymer-Based Formulations

Biopolymer-Based Formulations
  • Author : Dr. Kunal Pal,Indranil Banerjee,Preetam Sarkar,Doman Kim,Win-Ping Deng,Navneet Kumar Dubey,Kaustav Majumder
  • Publisher :Unknown
  • Release Date :2020-01-18
  • Total pages :966
  • ISBN : 9780128168981
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Summary : Biopolymer-Based Formulations: Biomedical and Food Applications presents the latest advances in the synthesis and characterization of advanced biopolymeric formulations and their state-of-the-art applications across biomedicine and food science. Sections cover the fundamentals, applications, future trends, environmental, ethical and medical considerations, and biopolymeric architectures that are organized in nano, micro and macro scales. The final section of the book focuses on novel applications and recent developments. This book is an essential resource for researchers, scientists and advanced students in biopolymer science, polymer science, polymer chemistry, polymer composites, plastics engineering, biomaterials, materials science, biomedical engineering, and more. It will also be of interest to R&D professionals, scientists and engineers across the plastics, food, biomedical and pharmaceutical industries. Provides in-depth coverage of methods for the characterization of the physical properties of biopolymeric architectures Supports a range of novel applications, including scaffolds, implant coatings, drug delivery, and nutraceutical encapsulation systems Includes the use of experimental data and mathematical modeling, thus enabling the reader to analyze and compare the properties of different polymeric gels

The Truth About The Drug Companies

The Truth About The Drug Companies
  • Author : Marcia Angell
  • Publisher :Unknown
  • Release Date :2005
  • Total pages :319
  • ISBN : 9780375760945
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Summary : A physician and former editor-in-chief of The New England Journal of Medicine provides an explosive critique of the pharmaceutical industry, detailing its dangerous influence on medical research, education, and physicians; exposing the reasons behind the spiraling prescription drug prices; and proposing a program of vital reforms. Reprint.

Colloids in Biotechnology

Colloids in Biotechnology
  • Author : Monzer Fanun
  • Publisher :Unknown
  • Release Date :2010-09-17
  • Total pages :547
  • ISBN : 1439830819
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Summary : Colloids show great potential in a wide variety of applications, including drug delivery and medical imaging, and the design and fabrication of colloid systems has attracted considerable interest in the research community. Colloids in Biotechnology describes developments in the field of biotechnological applications in the past decade and bridges the gap between these research efforts and commercially viable options. Highlights the role of colloids in a plethora of biotechnical applications Striking a balance between theory and experiment, between principles and applications, and between molecular and physical approaches to the subject, the book assembles contributions from an international community of colloid scientists to provide a comprehensive reference on the role of colloids in biotechnology and biomedicine. The authors discuss new types of biosurfactants; mixtures of surfactants; and peptides, proteins, and polyelectrolytes. They also describe the formation and properties of magnetic colloids and review their applications in chemical biology and medicine. They highlight current progress in the design of self-assembled materials for biotechnology, and they also cover the formation of nanofibres and the use of sol-gel technology in biology. Contains contributions from a diverse team of researchers The chapter authors have been given the freedom to present the spectrum of the relevant science, from pure to applied, in their particular topic. The compilation of this vast experience makes this text a valuable reference for those working in research and development in a range of technologies as well as academic scientists in the colloid and surface science field.

Peptide-based Biomaterials

Peptide-based Biomaterials
  • Author : Mustafa O. Guler
  • Publisher :Unknown
  • Release Date :2020-11-26
  • Total pages :487
  • ISBN : 9781839161155
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Summary : Research and new tools in biomaterials development by using peptides are currently growing, as more functional and versatile building blocks are used to design a host of functional biomaterials via chemical modifications for health care applications. It is a field that is attracting researchers from across soft matter science, molecular engineering and biomaterials science. Covering the fundamental concepts of self-assembly, design and synthesis of peptides, this book will provide a solid introduction to the field for those interested in developing functional biomaterials by using peptide derivatives. The bioactive nature of the peptides and their physical properties are discussed in various applications in biomedicine. This book will help researchers and students working in biomaterials and biomedicine fields and help their understanding of modulating biological processes for disease diagnosis and treatments.

An Introduction to Biotechnology

An Introduction to Biotechnology
  • Author : W T Godbey
  • Publisher :Unknown
  • Release Date :2014-12-08
  • Total pages :436
  • ISBN : 9781908818485
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Summary : An Introduction to Biotechnology is a biotechnology textbook aimed at undergraduates. It covers the basics of cell biology, biochemistry and molecular biology, and introduces laboratory techniques specific to the technologies addressed in the book; it addresses specific biotechnologies at both the theoretical and application levels. Biotechnology is a field that encompasses both basic science and engineering. There are currently few, if any, biotechnology textbooks that adequately address both areas. Engineering books are equation-heavy and are written in a manner that is very difficult for the non-engineer to understand. Numerous other attempts to present biotechnology are written in a flowery manner with little substance. The author holds one of the first PhDs granted in both biosciences and bioengineering. He is more than an author enamoured with the wow-factor associated with biotechnology; he is a practicing researcher in gene therapy, cell/tissue engineering, and other areas and has been involved with emerging technologies for over a decade. Having made the assertion that there is no acceptable text for teaching a course to introduce biotechnology to both scientists and engineers, the author committed himself to resolving the issue by writing his own. The book is of interest to a wide audience because it includes the necessary background for understanding how a technology works. Engineering principles are addressed, but in such a way that an instructor can skip the sections without hurting course content The author has been involved with many biotechnologies through his own direct research experiences. The text is more than a compendium of information - it is an integrated work written by an author who has experienced first-hand the nuances associated with many of the major biotechnologies of general interest today.

Drug Delivery Nanosystems for Biomedical Applications

Drug Delivery Nanosystems for Biomedical Applications
  • Author : Chandra P Sharma
  • Publisher :Unknown
  • Release Date :2018-08-22
  • Total pages :451
  • ISBN : 9780323509237
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Summary : Drug Delivery Nanosystems for Biomedical Application reviews some of the most challenging nanosystems with different routes of delivery that are useful for specific drugs, from both efficacy and bioavailability points-of-view. The chapters explore how this area is developing, the present state of the field, and future developments, in particular, inorganic, metallic, polymeric, composite and lipid nanosystems and their possible evolution to clinical applications. The book is a valuable research reference for both researchers and industrial partners who are not only interested in learning about this area, but also want to gain insights on how to move towards translational research. Focuses on applications, including tissue engineering and regenerative technologies, showing how nanosystems are used in practice Explores how nanosystems are used to deliver a variety of drugs, including peptides, hormone growth factors and genes Assesses the safety and nanotoxicity aspects of drug delivery nanosystems

Emerging Concepts in Analysis and Applications of Hydrogels

Emerging Concepts in Analysis and Applications of Hydrogels
  • Author : Sutapa Biswas Majee
  • Publisher :Unknown
  • Release Date :2016-08-24
  • Total pages :266
  • ISBN : 9789535125099
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Summary : This book is an Up-to-date and authoritative account on physicochemical principles, pharmaceutical and biomedical applications of hydrogels. It consists of eight contributions from different authors highlighting properties and synthesis of hydrogels, their characterization by various instrumental methods of analysis, comprehensive review on stimuli-responsive hydrogels and their diverse applications, and a special section on self-healing hydrogels. Thus, this book will equip academia and industry with adequate basic and applied principles related to hydrogels.

Boron Nitride Nanotubes in Nanomedicine

Boron Nitride Nanotubes in Nanomedicine
  • Author : Gianni Ciofani,Virgilio MATTOLI
  • Publisher :Unknown
  • Release Date :2016-04-26
  • Total pages :246
  • ISBN : 9780323389600
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Summary : Boron Nitride Nanotubes in Nanomedicine compiles, for the first time in a single volume, all the information needed by researchers interested in this promising type of smart nanoparticles and their applications in biomedicine. Boron nitride nanotubes (BNNTs) represent an innovative and extremely intriguing class of nanomaterials. After introducing BNNTs and explaining their preparation and evaluation, the book shows how the physical, chemical, piezoelectric and biocompatibility properties of these nanotubes give rise to their potential uses in biomedicine. Evidence is offered (from both in vitro and in vivo investigations) for how BNNTs can be useful in biomedical and nanomedicine applications such as therapeutic applications, tissue regeneration, nanovectors for drug delivery, and intracellular nanotransducers. Covers a range of promising biomedical BNNT applications Provides great value not just to academics but also industry researchers in fields such as materials science, molecular biology, pharmacology, biomedical engineering, and biophysical sciences Offers evidence for how BNNTs can be useful in biomedical and nanomedicine applications such as therapy, tissue regeneration, nanovectors for drug delivery, and intracellular nanotransducers Incorporates, for the first time in a single volume, all the information needed by researchers interested in this promising type of smart nanoparticles and their applications in biomedicine

Plant Cyclotides

Plant Cyclotides
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2015-11-24
  • Total pages :370
  • ISBN : 9780128007976
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Summary : Advances in Botanical Research publishes in-depth and up-to-date reviews on a wide range of topics in plant sciences. Currently in its 76th volume, the series features several reviews by recognized experts on all aspects of plant genetics, biochemistry, cell biology, molecular biology, physiology and ecology. Publishes in-depth and up-to-date reviews on a wide range of topics in plant sciences Contains commentary by recognized experts on all aspects of plant genetics, biochemistry, cell biology, molecular biology, physiology, and ecology This volume features reviews of the fast moving field of plant cyclotides

BioMEMS and Biomedical Nanotechnology

BioMEMS and Biomedical Nanotechnology
  • Author : Tejal Desai,Sangeeta N. Bhatia
  • Publisher :Unknown
  • Release Date :2007-05-26
  • Total pages :376
  • ISBN : 9780387258447
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Summary : Volume 3 of the multi-volume reference, BioMEMS and Biomedical Nanotechnology, will be the first comprehensive treatment of the emerging area of therapeutic micro- and nanotechnology. Subjects covered include: cell-based therapeutics, regenerative medicine - merging cells with micro- and nanosystems, and integrating MEMS with cells and tissues; Drug delivery - intravascular nanoparticles for drug targeting and nonvascular delivery (implantable, oral, inhalable); and, molecular surface engineering for the biological interface, biomolecule patterning and cell patterning. This volume is very well illustrated with many of the figures in color.

Fluorescence-Based Biosensors

Fluorescence-Based Biosensors
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2012-12-31
  • Total pages :416
  • ISBN : 9780123869517
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Summary : One of the major challenges of modern biology and medicine consists in finding means to visualize biomolecules in their natural environment with the greatest level of accuracy, so as to gain insight into their properties and behaviour in a physiological and pathological setting. This has been achieved thanks to the design of novel imaging agents, in particular to fluorescent biosensors. Fluorescence Biosensors comprise a large set of tools which are useful for fundamental purposes as well as for applications in biomedicine, drug discovery and biotechnology. These tools have been designed and engineered thanks to the combined efforts of chemists and biologists over the last decade, and developed hand in hand together with imaging technologies. This volume will convey the many exciting developments the field of fluorescent biosensors and reporters has witnessed over the recent years, from concepts to applications, including chapters on the chemistry of fluorescent probes, on technologies for monitoring protein/protein interactions and technologies for imaging biosensors in cultured cells and in vivo. Other chapters are devoted to specific examples of genetically-encoded reporters, or to protein and peptide biosensors, together with examples illustrating their application to cellular and in vivo imaging, biomedical applications, drug discovery and high throughput screening. Contributions from leading authorities Informs and updates on all the latest developments in the field

A Buyer's and User's Guide to Astronomical Telescopes and Binoculars

A Buyer's and User's Guide to Astronomical Telescopes and Binoculars
  • Author : James Mullaney
  • Publisher :Unknown
  • Release Date :2013-10-10
  • Total pages :223
  • ISBN : 9781461487333
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Summary : Amateur astronomers of all skill levels are always contemplating their next telescope, and this book points the way to the most suitable instruments. Similarly, those who are buying their first telescopes – and these days not necessarily a low-cost one – will be able to compare and contrast different types and manufacturers. This exciting and revised new guide provides an extensive overview of binoculars and telescopes. It includes detailed up-to-date information on sources, selection and use of virtually every major type, brand, and model on today’s market, a truly invaluable treasure-trove of information and helpful advice for all amateur astronomers. Originally written in 2006, much of the first edition is inevitably now out of date, as equipment advances and manufacturers come and go. This second edition not only updates all the existing sections of “A Buyer’s and User’s Guide to Astronomical Telescopes and Binoculars” but adds two new ones: Astro-imaging and Professional-Amateur collaboration. Thanks to the rapid and amazing developments that have been made in digital cameras – not those specialist cool-chip astronomical cameras, not even DSLRs, but regular general-purpose vacation cameras – it is easily possible to image all sorts of astronomical objects and fields. Technical developments, including the Internet, have also made it possible for amateur astronomers to make a real contribution to science by working with professionals. Selecting the right device for a variety of purposes can be an overwhelming task in a market crowded with observing options, but this comprehensive guide clarifies the process. Anyone planning to purchase binoculars or telescopes for astronomy – whether as a first instrument or as an upgrade to the next level – will find this book a treasure-trove of information and advice. It also supplies the reader with many useful hints and tips on using astronomical telescopes or binoculars to get the best possible results from your purchase.

Vaccines

Vaccines
  • Author : Farhat Afrin,Hassan Hemeg,Hani Ozbak
  • Publisher :Unknown
  • Release Date :2017-09-06
  • Total pages :192
  • ISBN : 9789535134756
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Summary : Microbes that elude host's defenses and have developed resistance to the existing antibiotic arsenal continuously invade the human body. Cure for such diseases is inevitable as it may result in high morbidity and mortality, if not properly treated. Vaccination represents the most cost-effective way for disease prevention. Vaccines activate sentinels of the immune system including macrophages and T, B, and dendritic cells to release a battery of effector molecules and cytokines and ward off infection. For long-lasting protection, the memory cells also need to be evoked. This book encompasses biotechnological vaccines in clinical use, cocooning, disease resurgence postvaccination and other vaccine adverse effects, prospects of therapeutic versus prophylactic vaccines, and design of effective vaccines using bioinformatic tools and engineering molecular pattern interactions.