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A Pharmacology Primer

A Pharmacology Primer
  • Author : Terry Kenakin
  • Publisher :Unknown
  • Release Date :2018-10-26
  • Total pages :488
  • ISBN : 9780128139585
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Summary : A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, Fifth Edition features the latest ideas and research regarding the application of pharmacology to the process of drug discovery. Written by well-respected pharmacologist, Terry P. Kenakin, this primer is an indispensable resource for all those involved in drug discovery. This updated edition has been thoroughly revised to include material on quantifying drug efficacy through bias and cluster analysis, the impact of molecular dynamics and protein structural analysis, the real time kinetic analysis of drug effect, virtual screening for new drug chemical scaffolds, and much more. With full color illustrations and new examples throughout, this book remains a top reference for all industry and academic scientists that is also ideal for students directly involved in drug discovery or pharmacologic research. Highlights changes surrounding strategies for drug discovery, providing a comprehensive reference and featuring advances in the methods involved Includes multiple new sections, such as development and utilization of models in pharmacology, de-orphanization of new drug targets, predicting impact of disease on drug pharmacokinetics, and the impact of enzyme kinetics on drug-drug interactions Illustrates the application of rapid inexpensive assays to predict activity in the therapeutic setting, showing data outcomes and the limitations inherent in interpreting this data

Cannabinoid Pharmacology

Cannabinoid Pharmacology
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2017-08-18
  • Total pages :492
  • ISBN : 9780128112335
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Summary : Cannabinoid Pharmacology, Volume 80 is a new volume in the Advances in Pharmacology that presents reviews of recent breakthroughs. This volume aims to present current knowledge of the endogenous cannabinoid system, and looks at molecular, cellular, tissue and organismal effects of endogenous and exogenous cannabinoids. Topics of note in this new volume include Endocannabinoids and their congeners, Endocannabinoid turnover, Plant cannabinoids, Synthetic cannabinoids and ‘legal highs’, CB1 and CB2 cannabinoid receptors, Novel signaling modalities, Novel cannabinoid receptors, and Ion channel regulation by cannabinoids. There is a broad coverage of the essential elements associated with the cannabinoid system. The Editors have sought to include authors who represent authoritative voices on these themes, but have not previously worked together to allow a fresh approach to the individual aspects covered. Presents reviews of recent breakthroughs in the cannabinoid system Features chapters from the best authors in the field Provides an essential resource for scientists, advanced undergraduate students through to established faculty members

Cardiovascular Pharmacology: Heart and circulation

Cardiovascular Pharmacology: Heart and circulation
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2010-11-26
  • Total pages :344
  • ISBN : 0123849047
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Summary : Cardiovascular disease remains a major cause of death and disability in developed countries and, increasingly so, in the developing world. Presented in this volume of Advances in Pharmacology are some of the most promising possibilities for treating large numbers of individuals afflicted with these conditions. Contains up-to-date reviews of the most important emerging cardiovascular therapies written by world leaders in the field

Pharmacology

Pharmacology
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :1993
  • Total pages :229
  • ISBN : UCLA:L0071943062
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Summary :

Principles of Clinical Pharmacology

Principles of Clinical Pharmacology
  • Author : Arthur J. Atkinson, Jr.,Darrell R. Abernethy,Charles E. Daniels,Robert Dedrick,Sanford P. Markey
  • Publisher :Unknown
  • Release Date :2011-04-28
  • Total pages :568
  • ISBN : 0080466427
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Summary : This revised second edition covers the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development, focusing on the fundamentals that underlie the clinical use and contemporary development of pharmaceuticals. Authors drawn from academia, the pharmaceutical industry and government agencies cover the spectrum of material, including pharmacokinetic practice questions, covered by the basic science section of the certifying examination offered by the American Board of Clinical Pharmacology. This unique reference is recommended by the Board as a study text and includes modules on drug discovery and development to assist students as well as practicing pharmacologists. Unique breadth of coverage ranging from drug discovery and development to individualization and quality assessment of drug therapy Unusual cohesive of presentation that stems from author participation in an ongoing popular NIH course Instructive linkage of pharmacokinetic theory and applications with provision of sample problems for self-study Wide-ranging perspective of authors drawn from the ranks of Federal agencies, academia and the pharmaceutical industry Expanded coverage of pharmacogenetics Expanded coverage of drug transporters and their role in interactions Inclusion of new material on enzyme induction mechanisms in chapters on drug metabolism and drug interactions A new chapter on drug discovery that focuses on oncologic agents Inclusion of therapeutic antibodies in chapter on biotechnology products

Annual Review of Pharmacology and Toxicology

Annual Review of Pharmacology and Toxicology
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :1977
  • Total pages :229
  • ISBN : UOM:39015007321410
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Summary :

Dental Pharmacology

Dental Pharmacology
  • Author : Northwestern University (Evanston, Ill.). Dental School. Pharmacology Dept
  • Publisher :Unknown
  • Release Date :1988
  • Total pages :229
  • ISBN : NWU:35557000219707
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Summary :

Homoeopathic Pharmacology

Homoeopathic Pharmacology
  • Author : Frederick O. Ernesty
  • Publisher :Unknown
  • Release Date :1899
  • Total pages :119
  • ISBN : UOM:39015065223755
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Summary :

Elements of Pharmacology

Elements of Pharmacology
  • Author : Oswald Schmiedeberg
  • Publisher :Unknown
  • Release Date :1887
  • Total pages :223
  • ISBN : UCAL:$B171612
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Summary :

Advances in Pharmacology and Chemotherapy

Advances in Pharmacology and Chemotherapy
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :1971-04-20
  • Total pages :259
  • ISBN : 9780080580999
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Summary : Advances in Pharmacology and Chemotherapy

Pharmacology in Drug Discovery and Development

Pharmacology in Drug Discovery and Development
  • Author : Terry Kenakin
  • Publisher :Unknown
  • Release Date :2016-10-21
  • Total pages :350
  • ISBN : 9780128037539
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Summary : Pharmacology in Drug Discovery and Development: Understanding Drug Response, Second Edition, is an introductory resource illustrating how pharmacology can be used to furnish the tools necessary to analyze different drug behavior and trace this behavior to its root cause or molecular mechanism of action. The concepts discussed in this book allow for the application of more predictive pharmacological procedures aimed at increasing therapeutic efficacy that will lead to more successful drug development. Chapters logically build upon one another to show how to characterize the pharmacology of any given molecule and allow for more informed predictions of drug effects in all biological systems. New chapters are dedicated to the interdisciplinary drug discovery environment in both industry and academia, and special techniques involved in new drug screening and lead optimization. This edition has been fully revised to address the latest advances and research related to real time kinetic assays, pluridimensional efficacy, signaling bias, irreversible and chemical antagonism, allosterically-induced bias, pharmacokinetics and safety, target and pathway validation, and much more. With numerous valuable chapter summaries, detailed references, practical examples and case studies throughout, Dr. Kenakin successfully navigates a highly complex subject, making it accessible for students, professors, and new researchers working in pharmacology and drug discovery. Includes example-based cases that illustrate how the pharmacological concepts discussed in this book lead to practical outcomes for further research Provides vignettes on those researchers and scientists who have contributed significantly to the fields of pharmacology and drug discovery throughout history Offers sample questions throughout the book and an appendix containing answers for self-testing and retention

Clinical Pharmacology for Prescribing

Clinical Pharmacology for Prescribing
  • Author : Federico Dajas-Bailador
  • Publisher :Unknown
  • Release Date :2019-09-16
  • Total pages :752
  • ISBN : 9780199694938
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Summary : Clinical Pharmacology for Prescribing explains how drugs work and why they should be prescribed for common medical conditions. Linking disease processes to pharmacological interventions, this guide gives a sound basis for evidence based prescribing. Written for medical students, trainee doctors and non-medical prescribers, it addresses all aspects of practical pharmacology, explaining drug classes, their mechanisms and effects on the body. Ultimately its focus is on clinical use, so that safe prescribing decisions are based on sound understanding of science - why and how drugs work to treat common conditions. Every chapter provides clear linkages between pathophysiology of disease and drug mechanisms, highlighted in original illustrations that bring together drug mechanisms, pathways and their place in medical management. Unwanted effects, drug interactions and prescribing warnings are emphasised to help the reader become aware of critical issues in prescribing. This resource also addresses how to prescribe for vulnerable patient groups and provokes deep understanding for patient safety. Written by a Practicing Pharmaceutical Physician with a D.Phil in Pharmacology, an Assistant Professor with the Faculty of Medicine and Health Sciences and a Senior hospital-based Clinical Pharmacist. The textbook has been extensively reviewed by practicing clinicians such that this new resource exemplifies the skills and knowledge needed for practical, legal and safe clinical prescribing.

The Pharmacology of the opium alkaloids v. 2

The Pharmacology of the opium alkaloids v. 2
  • Author : Hugo Martin Krueger
  • Publisher :Unknown
  • Release Date :1941
  • Total pages :229
  • ISBN : STANFORD:24503219310
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Summary :

Pharmacology and Pharmacotherapeutics

Pharmacology and Pharmacotherapeutics
  • Author : R. S. Satoskar,Nirmala Rege,S. D. Bhandarkar
  • Publisher :Unknown
  • Release Date :2017-08-10
  • Total pages :1200
  • ISBN : 9788131249413
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Summary : The 25th revised edition of Pharmacology and Pharmacotherapeutics continues to maintain its status as an up-to-date, accurate and reliable text for medical students as well as practicing physicians. The advances in molecular biology have significantly influenced the understanding of pathogenesis of diseases and development of newer drugs. The real challenge, however, remains in application of the available information while treating a patient. This book has always placed before the readers an integrated approach intertwining current knowledge of pathophysiology of the disease, pharmacology of available drugs and strategies for medical management of diseases. The current edition balances the complexity and simplicity of scientific content to provide students of medicine and/or pharmacy an insight into rational therapeutics. It gives several practical tips which empowers the physician to treat patients effectively and confidently. Written in an integrated fashion, Pharmacology and Pharmacotherapeutics builds up a strong foundation of scientific knowledge to guide decision making and to promote a holistic approach towards patient care in clinical practice. Emphasis on Clinical Pharmacology in each chapter Current guidelines for therapeutic decisions Newer sedatives-hypnotics Hypertension management: Updates Advances in treatment of obesity and hyperlipidemia Newer antiepileptics Antiviral agents for hepatitis C Rheumatoid arthritis: pharmacotherapy Management of pulmonary hypertension Newer antidiabetic drugs Advances in immunotherapeutics Vitamin D and calcium: Updates Therapeutic advances for infectious diseases

Pharmacology

Pharmacology
  • Author : Miles Hacker,William S. Messer,Kenneth A. Bachmann
  • Publisher :Unknown
  • Release Date :2009-06-19
  • Total pages :608
  • ISBN : 0080919227
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Summary : Pharmacology meets the rapidly emerging needs of programs training pharmacologic scientists seeking careers in basic research and drug discovery rather than such applied fields as pharmacy and medicine. While the market is crowded with many clinical and therapeutic pharmacology textbooks, the field of pharmacology is booming with the prospects of discovering new drugs, and virtually no extant textbook meets this need at the student level. The market is so bereft of such approaches that many pharmaceutical companies will adopt Hacker et al. to help train new drug researchers. The boom in pharmacology is driven by the recent decryption of the human genome and enormous progress in controlling genes and synthesizing proteins, making new and even custom drug design possible. This book makes use of these discoveries in presenting its topics, moving logically from drug receptors to the target molecules drug researchers seek, covering such modern topics along the way as side effects, drug resistance, pharmacogenomics, and even nutriceuticals, one in a string of culminating chapters on the drug discovery process. The book is aimed at advanced undergraduates and beginning graduate students in medical, pharmacy, and graduate schools looking for a solid introduction to the basic science of pharmacology and envisioning careers in drug research. Uses individual drugs to explain molecular actions Full color art program explains molecular and chemical concepts graphically Logical structure reflecting the current state of pharmacology and translational research Covers such intricacies as drug resistance and cell death Consistent format across chapters and pedagogical strategies make this textbook a superior learning tool

Pharmacology for Nurses

Pharmacology for Nurses
  • Author : Blaine T. Smith
  • Publisher :Unknown
  • Release Date :2018-12-01
  • Total pages :500
  • ISBN : 9781284141986
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Summary : Pharmacology for Nurses, Second Edition teaches undergraduate nursing students the basic concepts of pharmacology.

Pharmacology

Pharmacology
  • Author : Richard Finkel (PharmD.),Michelle Alexia Clark,Luigi X. Cubeddu
  • Publisher :Unknown
  • Release Date :2009
  • Total pages :564
  • ISBN : 0781771552
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Summary : Lippincott's Illustrated Reviews: Pharmacology, Fourth Edition enables rapid review and assimilation of large amounts of complex information about the essentials of medical pharmacology. Clear, sequential pictures of mechanisms of action actually show students how drugs work, instead of just telling them. As in previous editions, the book features an outline format, over 500 full-color illustrations, cross-references to other volumes in the series, and over 125 review questions. Content has been thoroughly updated, and a new chapter covers toxicology. New to this edition will be a companion Website containing all of the illustrations, fully searchable text, and an interactive question bank.

Lectures on Pharmacology for Practitioners and Students

Lectures on Pharmacology for Practitioners and Students
  • Author : Carl Binz
  • Publisher :Unknown
  • Release Date :1895
  • Total pages :229
  • ISBN : UOM:39015072896148
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Summary :

Introduction to Pharmacology, Third Edition

Introduction to Pharmacology, Third Edition
  • Author : Mannfred A. Hollinger
  • Publisher :Unknown
  • Release Date :2002-11-28
  • Total pages :432
  • ISBN : 1420024124
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Summary : The first edition of Introduction to Pharmacology has over recent years become a highly influential text among students wishing to acquire a knowledge of pharmacology without having to refer to the larger, more detailed, traditional pharmacology volumes. This revised and updated second edition contains significant new material to bring the reader up-to-date with the latest practices and principles in pharmacology. Exploring the basic principles in both the therapeutic and toxicological aspects of drug use, the book employs contemporary examples of medication, supplemented with an increased number of accurate and easy-to-interpret figures and diagrams. Additionally, Introduction to Pharmacology presents the important concept of understanding the limitations surrounding the drugs that cure, replace physiological inadequacies, or treat symptoms, and which have led to the system of drug classification. The broad scope of the book also encompasses the role of the FDA, drugs in sport, and the use of animals for drug experimentation. A clear and accessible book, Introduction to Pharmacology builds on the strengths of the first edition and is an invaluable reference for all students interested in this subject.

A Treatise on Therapeutics, and Pharmacology, Or Materia Medica

A Treatise on Therapeutics, and Pharmacology, Or Materia Medica
  • Author : George Bacon Wood
  • Publisher :Unknown
  • Release Date :1868
  • Total pages :229
  • ISBN : OSU:32435081593816
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Summary :

Pharmacology

Pharmacology
  • Author : Dave Boothroyd
  • Publisher :Unknown
  • Release Date :2011
  • Total pages :229
  • ISBN : OCLC:1106152717
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Summary : The Living Books About Life series is written and produced by humanities scholars from universities across the world. Funded by JISC and published by the Open Humanities Press, the books present recent research on these subjects using interactive maps, podcasts and audio-visual materials. The result, which can be shared freely amongst both academic and non-academic individuals alike, is an engaging and diverse resource for researching and teaching relevant science issues across the humanities.