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Polymers and Nanomaterials for Gene Therapy

Polymers and Nanomaterials for Gene Therapy
  • Author : Ravin Narain
  • Publisher :Unknown
  • Release Date :2016-01-09
  • Total pages :302
  • ISBN : 9780081005217
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Summary : Polymers and Nanomaterials for Gene Therapy provides the latest information on gene therapy, a topic that has attracted significant attention over the past two decades for the treatment of inherited and acquired genetic diseases. Major research efforts are currently focused on designing suitable carrier vectors that compact and protect oligonucleotides for gene therapy. The book explores the most recent developments in the field of polymer science and nanotechnology, and how these advancements have helped in the design of advanced materials. Non-viral vector systems, including cationic lipids, polymers, dendrimers, peptides and nanoparticles, are potential routes for compacting DNA for systemic delivery. However, unlike viral analogues that have no difficulty in overcoming cellular barriers and immune defense mechanisms, non-viral gene carriers consistently exhibit significant reduced transfection efficiency due to numerous extra- and intracellular obstacles. Therefore, biocompatibility and potential for large-scale production make these compounds increasingly attractive for gene therapy. This book contains chapters on the engineering of polymers and nanomaterials for gene therapy, and how they can form complexes with DNA and avoid both in vitro and in vivo barriers. Other chapters describe in vitro, ex vivo, in vivo gene therapy studies, and the current issues affecting non-viral gene therapy. Explores current challenges in the research of genetic diseases Discusses polymers for gene therapy and their function in designing advanced materials Provides examples of organic and inorganic nanomaterials for gene therapy Includes labeling, targeting, and assays Looks at characterization, physico-(bio)chemical properties, and applications

Polymeric Gene Delivery

Polymeric Gene Delivery
  • Author : Mansoor M. Amiji
  • Publisher :Unknown
  • Release Date :2004-09-29
  • Total pages :704
  • ISBN : 0203500474
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Summary : To treat disease or correct genetic disorders using gene therapy, the most suitable vehicle must be able to deliver genes to the appropriate tissues and cells in the body in a specific as well as safe and effective manner. While viruses are the most popular vehicles to date, their disadvantages include toxicity, limited size of genes they can carry, and limited scale of industrial production. Polymeric Gene Delivery: Principles and Applications is the first comprehensive book to specifically address polymeric gene delivery systems. Uniting the expertise of international academic and industrial scientists who are working in the area of polymeric vectors for gene delivery, it is written by prominent researchers directly involved in this field. The book is divided into five sections that deal with challenges and opportunities in gene delivery and the efficient delivery of genes into somatic cells using polymeric vectors. The authors discuss using biodegradable polymers, condensing and non-condensing polymeric systems, microspheres and nanospheres, and designing specialized delivery systems based on targeting strategies. Polymeric Gene Delivery: Principles and Applications accentuates the versatility of polymeric delivery systems, including the potential for biocompatibility, the ability to design their formulation and geometry for a specific purpose, and the ease of modification to the surface of polymeric carriers. This book is an up-to-date guide for researchers in the field and those interested in entering this dynamic field.

Gene Therapy

Gene Therapy
  • Author : Surendra Nimesh
  • Publisher :Unknown
  • Release Date :2013
  • Total pages :380
  • ISBN : 1907568409
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Summary : Gene therapy is emerging as a new class of therapeutics for the treatment of inherited and acquired diseases. However, poor cellular uptake and instability of DNA in the physiological milieu limits its therapeutic potential, hence a vector which can protect and efficiently transport DNA to the target cells must be developed. Nanotechnology-based non-viral vectors have been proposed as potential candidates. Various polymeric nanoparticles have been shown to be suitable, with high cellular uptake efficiencies and reduced cytotoxicity. These delivery vectors form condensed complexes with DNA which result in shielding against enzymatic degradation and enhanced cellular targeting. Advantages including easy manipulatibility, high stability, low cost and high payload, mean that nanoparticles from various polymers have been exploited. Gene therapy gives a systematic account of the many aspects of nanotechnology mediated gene therapy, from the preparation of nanoparticles to physicochemical characterization, and follows with applications in in vitro and in vivo models. This book emphasizes the various aspects of nanotechnology-based gene therapy, with initial chapters detailing the tools and techniques available for preparation and in vitro and in vivo characterization of nanoparticles. Later chapters provide exhaustive details on polymeric systems employed for gene therapy. Provides an overview of nanotechnology applications in gene therapy, from preparation of nanoparticles to in vitro and in vivo studies Details the tools and techniques available for preparation, characterization and in vitro and in vivo study of nanoparticles Details the limitations of nanoparticle-mediated gene therapy and proposes ways in which they may be overcome

Advanced Technology for Delivering Therapeutics

Advanced Technology for Delivering Therapeutics
  • Author : Sabyasachi Maiti,Kalyan Kumar Sen
  • Publisher :Unknown
  • Release Date :2017-05-11
  • Total pages :184
  • ISBN : 9789535131212
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Summary : The goal of any novel drug delivery system is to provide therapeutic benefits to the patients by increasing duration of drug action, reducing dosing frequency, and controlling drug release rate at the target site, thereby reducing unwanted side effects. Advanced Technology for Delivering Therapeutics is a reference book that covers recent developments in the field of drug delivery science and technology. The purpose of this book is to bring together descriptions of some selective technologies including new and promising nanotechnology currently being investigated for drug delivery applications. This book is a useful source of information for graduate and post-graduate students of pharmacy and biomedical science; pharmaceutical

Polymeric Nanoparticles as a Promising Tool for Anti-cancer Therapeutics

Polymeric Nanoparticles as a Promising Tool for Anti-cancer Therapeutics
  • Author : Prashant Kesharwani,Kishore M. Paknikar,Virendra Gajbhiye
  • Publisher :Unknown
  • Release Date :2019-07-08
  • Total pages :432
  • ISBN : 9780128173312
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Summary : Polymeric Nanoparticles as Promising Tool for Anti-cancer Therapeutics provides an understanding of polymeric compounds and their use in cancer therapies. The book begins by giving an overview of the current status, future challenges and potential utilization of polymeric nanoparticles. It then covers specific polymeric nanoparticles through contributions from world-renowned experts and researchers. Chapters examine specific polymeric nanoparticles, their development as potential targeted delivery systems, and cancer characteristics that can be targeted for therapy development. The book synthesizes current research trends in the field, thus enhancing existing knowledge of nanomedicine, drug delivery and therapeutic intervention strategies in human cancers. Users will find this to be an ideal reference for research scientists and those in the pharmaceutical and medical fields who are working to develop novel cancer therapies using nanoparticle-based delivery systems. Explores the development of polymeric nanoparticle systems for the purpose of cancer therapy Presents thoroughly analyzed data and results regarding the usage of polymeric nanoparticles-based platforms for the diagnosis and treatment of cancer Highlights various cancer characteristics that can be targeted for therapeutic development using polymeric nanoparticles

Polymeric Nanomaterials in Nanotherapeutics

Polymeric Nanomaterials in Nanotherapeutics
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2018-10-26
  • Total pages :558
  • ISBN : 9780128139332
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Summary : Polymeric Nanomaterials in Nanotherapeutics describes how polymeric nanosensors and nanorobotics are used for biomedical instrumentation, surgery, diagnosis and targeted drug delivery for cancer, pharmacokinetics, monitoring of diabetes and healthcare. Key areas of coverage include drug administration and formulations for targeted delivery and release of active agents (drug molecules) to non-healthy tissues and cells. The book demonstrates how these are applied to dental work, wound healing, cancer, cardiovascular diseases, neurodegenerative disorders, infectious diseases, chronic inflammatory diseases, metabolic diseases, and more. Methods of administration discussed include oral, dental, topical and transdermal, pulmonary and nasal, ocular, vaginal, and brain drug delivery and targeting. Drug delivery topics treated in several subchapters includes materials for active targeting and cases study of polymeric nanomaterials in clinical trials. The toxicity and regulatory status of therapeutic polymeric nanomaterials are also examined. The book gives a broad perspective on the topic for researchers, postgraduate students and professionals in the biomaterials, biotechnology, and biomedical fields. Shows how the properties of polymeric nanomaterials can be used to create more efficient medical treatments/therapies Demonstrates the potential and range of applications of polymeric nanomaterials in disease prevention, diagnosis, drug development, and for improving treatment outcomes Accurately explains how nanotherapeutics can help in solving problems in the field through the latest technologies and formulations

Advances in Nanomaterials

Advances in Nanomaterials
  • Author : Mushahid Husain,Zishan Husain Khan
  • Publisher :Unknown
  • Release Date :2016-03-15
  • Total pages :429
  • ISBN : 9788132226680
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Summary : This book provides a review of the latest research findings and key applications in the field of nanomaterials. The book contains twelve chapters on different aspects of nanomaterials. It begins with key fundamental concepts to aid readers new to the discipline of nanomaterials, and then moves to the different types of nanomaterials studied. The book includes chapters based on the applications of nanomaterials for nano-biotechnology and solar energy. Overall, the book comprises chapters on a variety of topics on nanomaterials from expert authors across the globe. This book will appeal to researchers and professional alike, and may also be used as a reference for courses in nanomaterials.

Advances in Nanomaterials for Drug Delivery

Advances in Nanomaterials for Drug Delivery
  • Author : Mahdi Karimi,Maryam Rad Mansouri,Navid Rabiee,Michael R Hamblin
  • Publisher :Unknown
  • Release Date :2018-12-05
  • Total pages :78
  • ISBN : 9781681742892
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Summary : Nanomedicine is a developing field, which includes different disciplines such as material science, chemistry, engineering and medicine devoted to the design, synthesis and construction of high-tech nanostructures. The ability of these structures to have their chemical and physical properties tuned by structural modification, has allowed their use in drug delivery systems, gene therapy delivery, and various types of theranostic approaches. Colloidal noble metal nanoparticles and other nanostructures have many therapeutic and diagnostic applications. The concept of drug targeting as a magic bullet has led to much research in chemical modification to design and optimize the binding to targeted receptors. It is important to understand the precise relationship between the drug and the carrier and its ability to target specific tissues, and pathogens to make an efficient drug delivery system. This book covers advances based on different drug delivery systems: polymeric and hyper branched nanomaterials, carbon-based nanomaterials, nature-inspired nanomaterials, and pathogen-based carriers.

Nanomaterials for Drug Delivery and Therapy

Nanomaterials for Drug Delivery and Therapy
  • Author : Alexandru Mihai Grumezescu
  • Publisher :Unknown
  • Release Date :2019-03-14
  • Total pages :580
  • ISBN : 9780128166291
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Summary : Nanomaterials for Drug Delivery and Therapy presents recent advances in the field of nanobiomaterials and their important applications in drug delivery, therapy and engineering. The book offers pharmaceutical perspectives, exploring the development of nanobiomaterials and their interaction with the human body. Chapters show how nanomaterials are used in treatments, including neurology, dentistry and cancer therapy. Authored by a range of contributors from global institutions, this book offers a broad, international perspective on how nanotechnology-based advances are leading to novel drug delivery and treatment solutions. It is a valuable research resource that will help both practicing medics and researchers in pharmaceutical science and nanomedicine learn more on how nanotechnology is improving treatments. Assesses the opportunities and challenges of nanotechnology-based drug delivery systems Explores how nanotechnology is being used to create more efficient drug delivery systems Discusses which nanomaterials make the best drug carriers

Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids

Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids
  • Author : Surendra Nimesh,Ramesh Chandra,Nidhi Gupta
  • Publisher :Unknown
  • Release Date :2017-04-04
  • Total pages :256
  • ISBN : 9780081005637
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Summary : Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids addresses several issues related to safe and effective delivery of nucleic acids (NAs) using nanoparticles. A further emphasis would be laid on the mechanism of delivery of NAs, the barriers encountered and the strategies adapted to combat them. An exhaustive account of the advantages as well shortcomings of all the delivery vectors being employed in delivery of various NAs will be provided. On final note the regulatory aspects of nanoparticles mediated NA would be discussed, with focus on their clinical relevance. The design and development of nucleic acid-based therapeutics for the treatment of diseases arising from genetic abnormalities has made significant progress over the past few years. NAs have been widely explored for the treatment of cancer and infectious diseases or to block cell proliferation and thereby caused diseases. Advances in synthetic oligonucleotide chemistry resulted in synthesis of NAs that are relatively stable in in vivo environments. However, cellular targeting and intracellular delivery of NAs still remains a challenge. Further development of NA-based therapeutics depends on the progress of safe and effective carriers for systemic administration. Nanomedicine has facilitated availability of vectors with diminished cytotoxicity and enhanced efficacy which are rapidly emerging as systems of choice. These vectors protect NAs from enzymatic degradation by forming condensed complexes along with targeted tissue and cellular delivery. During the past few years, a myriad reports have appeared reporting delivery of NAs mediated by nanoparticles. This book will provide an overview of nanoparticles being employed in the in vitro and in vivo delivery of therapeutically relevant NAs like DNA, siRNA, LNA, PNA, etc. Provides a complete overview of the applicatiosn of nanomedicine in the delivery of nucleic acids, from characterization of nanoparticles, to in vitro and in vivo studies Discusses delivery issues of less well explored nucleic acids, like PNAs, Ribozymes, DNAzymes, etc. Summarizes the current state of research in nucleic acid delivery and underscores the future of nanomedicine in this field

Polymeric Gene Delivery Systems

Polymeric Gene Delivery Systems
  • Author : Yiyun Cheng
  • Publisher :Unknown
  • Release Date :2018-09-04
  • Total pages :358
  • ISBN : 9783319778662
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Summary : ​The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field. The chapter "Polymeric Nanoparticle-Mediated Gene Delivery for Lung Cancer Treatment" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Application of Nanotechnology in Drug Delivery

Application of Nanotechnology in Drug Delivery
  • Author : Ali Demir Sezer
  • Publisher :Unknown
  • Release Date :2014-07-25
  • Total pages :554
  • ISBN : 9789535116288
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Summary : This book collects reviews and original articles from eminent experts working in the interdisciplinary arena of nanotechnology use in drug delivery. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of nanotechnology application of drug delivery. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. On the other hand, this reference discusses advances in design, optimization, and adaptation of gene delivery systems for the treatment of cancer, cardiovascular, pulmonary, genetic, and infectious diseases, and considers assessment and review procedures involved in the development of gene-based pharmaceuticals.

Polymeric Nanomaterials in Nanotherapeutics

Polymeric Nanomaterials in Nanotherapeutics
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2018-10-26
  • Total pages :558
  • ISBN : 9780128139332
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Summary : Polymeric Nanomaterials in Nanotherapeutics describes how polymeric nanosensors and nanorobotics are used for biomedical instrumentation, surgery, diagnosis and targeted drug delivery for cancer, pharmacokinetics, monitoring of diabetes and healthcare. Key areas of coverage include drug administration and formulations for targeted delivery and release of active agents (drug molecules) to non-healthy tissues and cells. The book demonstrates how these are applied to dental work, wound healing, cancer, cardiovascular diseases, neurodegenerative disorders, infectious diseases, chronic inflammatory diseases, metabolic diseases, and more. Methods of administration discussed include oral, dental, topical and transdermal, pulmonary and nasal, ocular, vaginal, and brain drug delivery and targeting. Drug delivery topics treated in several subchapters includes materials for active targeting and cases study of polymeric nanomaterials in clinical trials. The toxicity and regulatory status of therapeutic polymeric nanomaterials are also examined. The book gives a broad perspective on the topic for researchers, postgraduate students and professionals in the biomaterials, biotechnology, and biomedical fields. Shows how the properties of polymeric nanomaterials can be used to create more efficient medical treatments/therapies Demonstrates the potential and range of applications of polymeric nanomaterials in disease prevention, diagnosis, drug development, and for improving treatment outcomes Accurately explains how nanotherapeutics can help in solving problems in the field through the latest technologies and formulations

Nanostructured Polymer Composites for Biomedical Applications

Nanostructured Polymer Composites for Biomedical Applications
  • Author : Sarat Kumar Swain,Mohammad Jawaid
  • Publisher :Unknown
  • Release Date :2019-06-15
  • Total pages :552
  • ISBN : 9780128168929
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Summary : Nanostructured Polymer Composites for Biomedical Applications addresses the challenges researchers face regarding the creation of nanostructured polymer composites that not only have superior performance and mechanical properties, but also have acceptable biological function. This book discusses current efforts to meet this challenge by discussing the multidisciplinary nature of nanostructured polymer composite biomaterials from various fields, including materials science, polymer science, biomedical engineering and biomedicine. This compilation of existing knowledge will lead to the generation of new terminology and definitions across individual disciplines. As such, this book will help researchers and engineers develop new products and devices for use in effective medical treatment. Summarizes the most recent strategies to develop nanostructured polymer composite biomaterials for biomedicine Outlines the major preparation and characterization techniques for a range of polymer nanocomposites used in biomedicine Explores the design of new types of nanostructured polymer composites for applications in drug delivery, tissue engineering, gene therapy and bone replacement

Polymer Science and Nanotechnology

Polymer Science and Nanotechnology
  • Author : Ravin Narain
  • Publisher :Unknown
  • Release Date :2020-06-16
  • Total pages :488
  • ISBN : 9780128168073
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Summary : Polymer Science and Nanotechnology: Fundamentals and Applications brings together the latest advances in polymer science and nanoscience. Sections explain the fundamentals of polymer science, including key aspects and methods in terms of molecular structure, synthesis, characterization, microstructure, phase structure and processing and properties before discussing the materials of particular interest and utility for novel applications, such as hydrogels, natural polymers, smart polymers and polymeric biomaterials. The second part of the book examines essential techniques in nanotechnology, with an emphasis on the utilization of advanced polymeric materials in the context of nanoscience. Throughout the book, chapters are prepared so that materials and products can be geared towards specific applications. Two chapters cover, in detail, major application areas, including fuel and solar cells, tissue engineering, drug and gene delivery, membranes, water treatment and oil recovery. Presents the latest applications of polymers and polymeric nanomaterials, across energy, biomedical, pharmaceutical, and environmental fields Contains detailed coverage of polymer nanocomposites, polymer nanoparticles, and hybrid polymer-metallic nanoparticles Supports an interdisciplinary approach, enabling readers from different disciplines to understand polymer science and nanotechnology and the interface between them

Nanocomposites for Musculoskeletal Tissue Regeneration

Nanocomposites for Musculoskeletal Tissue Regeneration
  • Author : Huinan Liu
  • Publisher :Unknown
  • Release Date :2016-02-23
  • Total pages :406
  • ISBN : 9781782424758
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Summary : Nanocomposites for Musculoskeletal Tissue Regeneration discusses the advanced biomaterials scientists are exploring for use as tools to mimic the structure of musculoskeletal tissues. Bone and other musculoskeletal tissues naturally have a nanocomposite structure, therefore nanocomposites are ideally suited as a material for replacing and regenerating these natural tissues. In addition, biological properties such as biointegration and the ability to tailor and dope the materials make them highly desirable for musculoskeletal tissue regeneration. Provides a comprehensive discussion on the design and advancements made in the use of nanocomposites for musculoskeletal tissue regeneration Presents an In-depth coverage of material properties Includes discussions on polymers, ceramics, and glass

Applications of Nanocomposite Materials in Drug Delivery

Applications of Nanocomposite Materials in Drug Delivery
  • Author : Dr Inamuddin,Abdullah M. Asiri,Ali Mohammad
  • Publisher :Unknown
  • Release Date :2018-06-18
  • Total pages :990
  • ISBN : 9780128137581
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Summary : Applications of Nanocomposite in Drug Delivery discusses and explores the applications of nanocomposites in the area of drug delivery. Starting with a scientific understanding of drug delivery fundamentals, the book explores the utility of nanocomposites in the area of controlled, transdermal, osteo-articular tuberculosis and stimulus sensitive drug delivery applications. The book intricately details and discusses a variety of methods for their preparation, while also highlighting specific applications of nanocomposites in targeted drug delivery. Discusses nanocomposite and nanotechnology for drug delivery Outlines the mechanisms involved in targeted drug delivery using nanocomposites Includes synthesis methods for nanocomposites used in controlled drug delivery Lists various applications of nanocomposites in drug delivery

Natural Polymer Drug Delivery Systems

Natural Polymer Drug Delivery Systems
  • Author : Saurabh Bhatia
  • Publisher :Unknown
  • Release Date :2016-09-23
  • Total pages :225
  • ISBN : 9783319411293
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Summary : This book describes 200 bio-polymers, including the most recent and advanced nanotechnology applications. The applications of various bio-medical and other future potential uses are covered and examined in depth. Systematic discussion of current leading natural polymers is also included.

Nucleic Acid Nanotheranostics

Nucleic Acid Nanotheranostics
  • Author : Marco Filice,Jesús Ruiz-Cabello
  • Publisher :Unknown
  • Release Date :2019-02-26
  • Total pages :491
  • ISBN : 9780128144718
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Summary : Nucleic Acid Nanotheranostics: Biomedical Applications offers a comprehensive overview of improvements and new trends in fabrication of nanostructures as theranostic multifunctional carriers in gene therapy. With a strong focus on medical applications (comprising diagnosis, therapy and imaging), the book also examines gene therapy in an individual patient’s cells or tissues to treat genetic diseases. Sections cover Biomedical and Diagnostic applications of Nucleic Acids, Biologic and Synthetic Advanced Nanostructures for nucleic acid delivery, and important considerations of nanomedicine. This book is a valuable guide for materials scientists, physicians, chemists and engineers, but is also ideal for clinicians wishing to expand their knowledge. Provides a unique source of knowledge (theoretical as well as practical) on nanotheranostic materials for gene therapy at all levels and related scientific areas Covers the pros and cons related to viral and nanomaterial-based delivery of nucleic acids in terms of biosafety, carrier selection, synthesis and bioimaging Presents the only book to include an analysis of nanoformulations approved for clinical use

Smart External Stimulus-Responsive Nanocarriers for Drug and Gene Delivery

Smart External Stimulus-Responsive Nanocarriers for Drug and Gene Delivery
  • Author : Mahdi Karimi,Parham Sahandi Zangabad,Amir Ghasemi,Michael R Hamblin
  • Publisher :Unknown
  • Release Date :2015-12-01
  • Total pages :155
  • ISBN : 9781681740102
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Summary : The concept of smart drug delivery vehicles involves designing and preparing a nanostructure (or microstructure) that can be loaded with a cargo, this can be a therapeutic drug, a contrast agent for imaging, or a nucleic acid for gene therapy. The nanocarrier serves to protect the cargo from degradation by enzymes in the body, to enhance the solubility of insoluble drugs, to extend the circulation half-life, and to enhance its penetration and accumulation at the target site. Importantly, smart nanocarriers can be designed to be responsive to a specific stimulus, so that the cargo is only released or activated when desired. In this volume we cover smart nanocarriers that respond to externally applied stimuli that usually involve application of physical energy. This physical energy can be applied from outside the body and can either cause cargo release, or can activate the nanostructure to be cytotoxic, or both. The stimuli covered include light of various wavelengths (ultraviolet, visible or infrared), temperature (increased or decreased), magnetic fields (used to externally manipulate nanostructures and to activate them), ultrasound, and electrical and mechanical forces. Finally we discuss the issue of nanotoxicology and the future scope of the field.

Nanoparticles in Pharmacotherapy

Nanoparticles in Pharmacotherapy
  • Author : Alexandru Mihai Grumezescu
  • Publisher :Unknown
  • Release Date :2019-04-15
  • Total pages :600
  • ISBN : 9780128165041
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Summary : Nanoparticles in Pharmacotherapy explores the most recent findings in how nanoparticles used in pharmacotherapy, starting with their synthesis, characterization and current or potential uses. Offering he book will be a valuable resource of recent scientific progress, along with most known applications of nanoparticles on the pharmacotherapy to be used by researchers, medical doctors and academia individuals.