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Primary Immunodeficiency Disorders

Primary Immunodeficiency Disorders
  • Author : Amos Etzioni,Hans D. Ochs
  • Publisher :Unknown
  • Release Date :2014-09-13
  • Total pages :376
  • ISBN : 9780124115545
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Summary : Primary Immunodeficiency Disorders: A Historic and Scientific Perspective provides a complete historical context that is crucial for students and researchers concerned with primary immunodeficiency. When researchers have a poor understanding of the way we arrived where we are in research, they can miss important points about a disease, or miss out on how to approach new diseases. This historical knowledge of research can assist greatly by showing how it was done in the past, demonstrating the successes and failures, so that it can be done better in the future. This book provides an understanding of the process going from clinical problem to lab and back to the clinic, based on historical experiences. Its chapters proceed from the discovery of the T and B cell lineages through the first BMT for immunodeficiency disorder; lab investigation and gene therapy for PID; the discovery of the gene for AT and its function; understanding cytokine defects; and many other stops along the way. Facilitates communication among physicians and other investigators concerned with immunological and inflammatory diseases Summarizes for the first time all the known facts from 60 years of primary immunodeficiency research, and teaches how an important field in medicine was established Provides stimulating discussions on developing new medical therapies Highlights the importance of studying humans to understand mechanisms of disease that affect humans

Primary Immunodeficiency Diseases

Primary Immunodeficiency Diseases
  • Author : Nima Rezaei,Asghar Aghamohammadi,Luigi D. Notarangelo
  • Publisher :Unknown
  • Release Date :2016-11-30
  • Total pages :582
  • ISBN : 9783662529096
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Summary : The number of diagnosed cases of primary immunodeficiency diseases (PIDs) – a group of inborn disorders of the immune system – is growing rapidly, but misdiagnosis or late diagnosis still occurs in a significant number of patients, with serious consequences. This is the second edition of a practical reference textbook on PIDs that has been widely welcomed by scientists and clinicians from around the world. The new edition has been extensively revised to reflect advances in knowledge and includes various PIDs not previously covered. For each disease, information is provided on definition, etiology, clinical manifestations, diagnosis, and management. This book will represent an ideal resource for specialists when engaging in diagnosis, clinical decision-making, and treatment planning. It will also prove invaluable for doctors in training and other physicians and nurses who wish to learn more about PIDs.

Primary Immunodeficiency Diseases

Primary Immunodeficiency Diseases
  • Author : Hans D. Ochs,C. I. Edvard Smith,Jennifer Puck
  • Publisher :Unknown
  • Release Date :2007
  • Total pages :726
  • ISBN : 9780195147742
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Summary : The second edition of Primary Immunodeficiency Diseases presents discussions of gene identification, mutation detection, and clinical and research applications for over 100 genetic immune disorders--disorders featuring an increased susceptibility to infections and, in certain conditions, an icreased rate of malignancies and autoimmune disorders. Since the publication of the first edition, a flurry of new disease entities has been defined and new treatment regimens have been introduced, the most spectacular being successful treatment by gene therapy for two genotypes of combined immunodeficiency. The first edition marked a historic turning point in the field of immunodeficiencies, demonstrating that many of the disorders of the immune systam could be understood at a molecular level. This new edition can proudly document the tremendous pace of progress in dissecting the complex immunologic networks responsible for protecting individuals from these disorders.

Clinical Cases in Primary Immunodeficiency Diseases

Clinical Cases in Primary Immunodeficiency Diseases
  • Author : Asghar Aghamohammadi,Nima Rezaei
  • Publisher :Unknown
  • Release Date :2012-12-13
  • Total pages :380
  • ISBN : 9783642317859
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Summary : Primary immunodeficiency diseases (PIDs) are a heterogeneous group of inherited disorders characterized by different defects in the development and function of the immune system. This book aims to increase the clinical awareness and knowledge of practicing clinicians regarding the diagnosis and management of PIDs. In order to achieve this goal, about 90 cases drawn from real life are presented, along with approximately 300 related questions. The selected case reports are the result of the invaluable cooperation of more than 40 scientists in the field of immunodeficiency. They focus both on the presenting features of patients with PIDs and on the required further investigation and management. Each of the numbered cases is followed by the questions, their answers, and additional discussion. Each question focuses on a particular aspect of the PID under consideration, and the topics covered include clinical diagnosis, laboratory findings, molecular mechanisms, and therapy.

Stiehm's Immune Deficiencies

Stiehm's Immune Deficiencies
  • Author : Kathleen E Sullivan,E. Richard Stiehm
  • Publisher :Unknown
  • Release Date :2014-08-08
  • Total pages :1156
  • ISBN : 9780124058606
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Summary : Stiehm's Immune Deficiencies focuses on immunodeficiencies in children and adults. This book covers the many advances in the study of immunodeficiency. Stiehm's Immune Deficiencies includes 62 chapters covering topics such as newly described syndromes, genetic diagnosis, molecular abnormalities, newborn screening, and current therapies. Provides practical guidance to practitioners dealing with the day-to-day issues of diagnosis and management of immune deficient patients Covers both clinical management and scientific advances in one place Includes newly described disorders in various periodic updates to maintain the breadth of the reference

Primary Immunodeficiencies Worldwide

Primary Immunodeficiencies Worldwide
  • Author : Menno C. van Zelm,Antonio Condino-Neto,Mohamed-Ridha Barbouche
  • Publisher :Unknown
  • Release Date :2020-02-19
  • Total pages :229
  • ISBN : 9782889635207
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Summary :

Pulmonary Manifestations of Primary Immunodeficiency Diseases

Pulmonary Manifestations of Primary Immunodeficiency Diseases
  • Author : Seyed Alireza Mahdaviani,Nima Rezaei
  • Publisher :Unknown
  • Release Date :2019-02-04
  • Total pages :286
  • ISBN : 3030008797
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Summary : This book provides a broad overview of the respiratory manifestations associated with Primary Immune deficiencies (PID) congenital genetic defects such as infections, chronic inflammation, autoimmunity, lymphoproliferation, allergic manifestations and rare forms of cancer. Since the most common site of involvement in PID is the lung, the pulmonologists (pediatrics or adult), Internists and General Practitioners may be among the first to recognize the pattern of pulmonary disorders, leading to diagnosis of PID. Pulmonary complications present a significant cause of morbidity and also mortality among patients suffering from different forms of PID. With the prevalence of lung infections and disease so high in PID patients, respiratory professionals will find this book to be an essential resource for diagnosing, managing and referring PID related pulmonary disorders in clinical practice.

Primary Immunodeficiency Disorders

Primary Immunodeficiency Disorders
  • Author : Lisa J. Kobrynski
  • Publisher :Unknown
  • Release Date :2019
  • Total pages :140
  • ISBN : OCLC:1082855989
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Summary :

Pediatric Immunology

Pediatric Immunology
  • Author : Nima Rezaei
  • Publisher :Unknown
  • Release Date :2019-10-08
  • Total pages :822
  • ISBN : 9783030212629
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Summary : This book comprises a collection of categorized case-based questions, directed and meticulously selected to cover the most common and most important aspects of immunodeficiency diseases. Immunodeficiency disorders of infancy and childhood such as antibody deficiencies, phagocyte defects and defects in innate immunity are addressed among others. Each chapters starts with a brief of the initial presentation and lab data of the patient, followed by a series of 5-6 multiple choice questions (MCQs), leading the reader to the diagnosis and best of practice in a step-wise manner. This MCQ format along with precise, yet detailed answer ensures a quick, case-based, reality learning to the reader. This comprehensive MCQ series, is an essential reading material that a pediatric clinician, hematologist, immunologist, transplant specialist, or pulmonologist, can not afford to miss.

The Immune Response

The Immune Response
  • Author : Tak W. Mak,Mary E. Saunders
  • Publisher :Unknown
  • Release Date :2005-11-11
  • Total pages :1216
  • ISBN : 9780080534480
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Summary : The Immune Response is a unique reference work covering the basic and clinical principles of immunology in a modern and comprehensive fashion. Written in an engaging conversational style, the book conveys the broad scope and fascinating appeal of immunology. The book is beautifully illustrated with superb figures as well as many full color plates. This extraordinary work will be an invaluable resource for lecturers and graduate students in immunology, as well as a vital reference for research scientists and clinicians studying related areas in the life and medical sciences. Current and thorough 30 chapter reference reviewed by luminaries in the field Unique ‘single voice' ensures consistency of definitions and concepts Comprehensive and elegant illustrations bring key concepts to life Provides historical context to allow fuller understanding of key issues Introductory chapters 1-4 serve as an ‘Immunology Primer' before topics are discussed in more detail

The EBMT Handbook

The EBMT Handbook
  • Author : Enric Carreras,Carlo Dufour,Mohamad Mohty,Nicolaus Kröger
  • Publisher :Unknown
  • Release Date :2018-12-12
  • Total pages :702
  • ISBN : 9783030022785
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Summary : This Open Access edition of the European Society for Blood and Marrow Transplantation (EBMT) handbook addresses the latest developments and innovations in hematopoietic stem cell transplantation and cellular therapy. Consisting of 93 chapters, it has been written by 175 leading experts in the field. Discussing all types of stem cell and bone marrow transplantation, including haplo-identical stem cell and cord blood transplantation, it also covers the indications for transplantation, the management of early and late complications as well as the new and rapidly evolving field of cellular therapies. This book provides an unparalleled description of current practices to enhance readers’ knowledge and practice skills.

Pediatric Allergy

Pediatric Allergy
  • Author : Nima Rezaei
  • Publisher :Unknown
  • Release Date :2019-08-13
  • Total pages :318
  • ISBN : 9783030182823
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Summary : This book comprises a collection of case-based chapters, submitted by physicians and pediatricians in all specialties and meticulously refined and selected to cover the most common and important aspects of Pediatric Allergy knowledge. Commonly encountered disorders such as allergic rhinitis, food allergy, and atopic dermatitis are covered among many others. Each chapter starts with a brief of the initial presentation and lab data of the patient, followed by a series of 3-6 multiple choice questions (MCQs), leading the reader to the diagnosis and best of practice in a step-wise manner. Clinical pearls presented as "practical points", and the MCQ format along with detailed answers, makes Pediatrc Allergy an essential reading material that a pediatric allergologist cannot afford to miss.

Critical Care of the Pediatric Immunocompromised Hematology/Oncology Patient

Critical Care of the Pediatric Immunocompromised Hematology/Oncology Patient
  • Author : Christine N. Duncan,Julie-An M. Talano,Jennifer A. McArthur
  • Publisher :Unknown
  • Release Date :2019-02-01
  • Total pages :417
  • ISBN : 9783030013226
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Summary : This volume provides a comprehensive overview of critical care of the pediatric immunocompromised hematology-oncology patient. The text focuses on unique aspects of the pediatric immunocompromised patient that predisposes the child to significant illness, and presents critical care management strategies specific to the patient population. In addition to chapters on oncology, primary immune deficiency, immunocompromised hematology, and hematopoietic cell transplant patients, the book covers the changing landscape of ICU care, pharmacologic considerations, and psychological and social aspects of the critical care of hematology-oncology patients. Written by experts from a range of disciplines, Critical Care of the Pediatric Immunocompromised Hematology/Oncology Patient: An Evidence-Based Guide is a valuable resource for clinicians and practitioners who treat this patient population.

Humoral Primary Immunodeficiencies

Humoral Primary Immunodeficiencies
  • Author : Mario Milco D'Elios,Marta Rizzi
  • Publisher :Unknown
  • Release Date :2018-12-29
  • Total pages :387
  • ISBN : 9783319917856
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Summary : This book presents detailed state of the art knowledge on the humoral primary immunodeficiencies (PIDs), i.e., disorders arising from impaired antibody production due to defects intrinsic to B cells or defective interaction between B and T cells. There is extensive coverage of both basic science discoveries and the latest clinical advances in the field. The book is structured in accordance with the most recent classification of PIDs and also covers updates on the B cell immunological synapse. Readers will find comprehensive, in-depth descriptions of novel humoral PID genes and related clinical applications, mucosal B cells, and the various clinical phenotypes of humoral PIDs. Aspects such as differential diagnosis, clinical management in children and adults, and the role of vaccines are also addressed. The authors are all recognized experts from Europe, Australia, and the United States. Humoral Primary Immunodeficiencies will be of high value for immunologists, pediatricians, rheumatologists, oncologists, internists, and infectious disease specialists and will also be informative for MD and PhD students.

Clinical Manual of Blood and Bone Marrow Transplantation

Clinical Manual of Blood and Bone Marrow Transplantation
  • Author : Syed A. Abutalib,Parameswaran Hari
  • Publisher :Unknown
  • Release Date :2017-04-19
  • Total pages :424
  • ISBN : 9781119095477
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Summary : Providing the practicing and trainee hematologist with a practical and immediately applicable compendium of answers the Clinical Manual of Blood and Bone Marrow Transplantation covers the spectrum of the hematopoietic cell transplant specialty, in particular practical issues in transplant patient care, and the set up and functioning of a transplant program. Supplies the practicing and trainee hematologist with a practical and immediately applicable compendium of answers to clinical questions Covers the spectrum of the hematopoietic cell transplant specialty, in particular practical issues in transplant patient care, and the set up and functioning of a transplant program Contains concise chapters written with a focus on tables, algorithms and figures to aid rapid referral Benefits from expert contributions from an international authorship

Neurologic Involvement in Primary Immunodeficiency Disorders

Neurologic Involvement in Primary Immunodeficiency Disorders
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2021
  • Total pages :229
  • ISBN : OCLC:1051932991
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Summary : The nervous system may be affected in primary immune deficiency (PID) syndromes through infectious, autoimmune, neoplastic mechanisms, or as a primary feature of the syndrome. However certain neurologic problems do not conform to these etiopathogenetic groups. We retrospectively examined PID patients seen in neurology consultation between 2014 and 2017 in order to determine the spectrum of nervous system involvement. Among patients with confirmed neurologic problems (n = 35), common manifestations were encephalopathy and global developmental/cognitive delay. In 13 (37%) instances, the neurologic signs had no apparent relation with a treatment-related, infectious, or vascular complication and were considered as primary findings: acquired microcephaly, central nervous system malformation, or peripheral neuropathy. The diagnosis of PID was made after, and based on, the neurologic manifestation in 6 of 35 (17%) patients. Neurologic presentation may constitute the initial manifestation in some types of primary immune deficiency.

Congenital Bleeding Disorders

Congenital Bleeding Disorders
  • Author : Akbar Dorgalaleh
  • Publisher :Unknown
  • Release Date :2018-07-25
  • Total pages :396
  • ISBN : 9783319767239
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Summary : This book describes in detail the clinical presentation, diagnosis, and management of a wide range of congenital bleeding disorders. It will assist readers in overcoming the significant challenges involved in clinical and laboratory diagnosis and in providing effective clinical care that makes optimal use of new products, including recombinant factor concentrate. The coverage ranges from hemophilia A and B and von Willebrand disease to rare bleeding disorders such as congenital factor V, factor X, factor XI, and factor XIII deficiency and inherited platelet function disorders. The exceptional attention to rarer conditions is of particular importance given the considerable risk of overlooking them during diagnosis, with potential consequences for disease-related morbidity and mortality. The authors are acknowledged specialists in the field from across the world who have particular expertise in the disorder that they discuss. The book will be of value to hematologists, oncologists, pediatricians, laboratory specialists and technicians, general physicians, and trainees.

Asthma

Asthma
  • Author : Richard F. Lockey,Dennis K. Ledford
  • Publisher :Unknown
  • Release Date :2014
  • Total pages :481
  • ISBN : 9780199918065
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Summary : Diagnosing asthma requires knowledge of the multiple conditions that emulate it, and treatment requires addressing factors that modify the disease. This comprehensive, single reference will help practitioners identify and care for co-morbid conditions and improve asthma treatment.

Immunopathology and Immunomodulation

Immunopathology and Immunomodulation
  • Author : Krassimir Metodiev
  • Publisher :Unknown
  • Release Date :2015-11-18
  • Total pages :312
  • ISBN : 9789535122104
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Summary : This book is a continuation of the efforts of InTech to expand the scientific know-how in the field of immunopathology and bring valuable updated information to medical professionals and researchers. It consists of chapters related to various approaches to investigate the unique role of the immune system in response to different clinical disorders. The international team of authors is the bonus of the book, reflecting the rapid development of immunology and new achievements in medical science. We firmly hope that the book will be an excellent manual and guideline for people dealing with biology, microbiology, immunology, virology, pharmacology, general and dental medicine, and health care, from students and postdocs to high-level specialists and university professors.

Tuberculosis in Adults and Children

Tuberculosis in Adults and Children
  • Author : Dorothee Heemskerk,Maxine Caws,Ben Marais,Jeremy Farrar
  • Publisher :Unknown
  • Release Date :2015-07-17
  • Total pages :66
  • ISBN : 9783319191324
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Summary : This work contains updated and clinically relevant information about tuberculosis. It is aimed at providing a succinct overview of history and disease epidemiology, clinical presentation and the most recent scientific developments in the field of tuberculosis research, with an emphasis on diagnosis and treatment. It may serve as a practical resource for students, clinicians and researchers who work in the field of infectious diseases.

Comprehensive Review of Infectious Diseases

Comprehensive Review of Infectious Diseases
  • Author : Andrej Spec,Gerome V. Escota,Courtney Chrisler,Bethany Davies
  • Publisher :Unknown
  • Release Date :2019-11-16
  • Total pages :650
  • ISBN : 9780323568647
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Summary : Perfect for board review or quick reference in clinical practice, Comprehensive Review of Infectious Diseases is a balanced, high-yield resource covering the full range of infectious disease topics. Whether you’re preparing for examinations or are looking for a concise resource to support your practice, this unique review contains precisely the information you need – from common infectious diseases concepts and conditions to hundreds of up-to-date review questions and answers for self-assessment and exam preparation. Covers the most frequently encountered concepts and conditions in infectious diseases. Covers challenging areas frequently covered on the boards: clinically-relevant microbiology and ID pharmacology, HIV and antiretroviral therapy, infections in immunocompromised hosts, dermatologic manifestations of ID, infection mimics, infection control and prevention, and more. Includes new and emerging topics such as neglected tropical diseases, bioterrorism, and emerging and re-emerging infections. Provides more than 550 case-based, board-style multiple-choice questions and answers for test prep and self-assessment. Facilitates quick review and maximum retention of information by including hundreds of high-quality illustrations, tables, high-yield boxes, and bulleted lists. Contains practical tips for taking the boards, buzzwords and memory aids for board questions, and clinical and board pearls. Edited and written by rising stars in the field of infectious diseases – authors who have recently taken the boards and excelled, and who understand the challenges posed by this complex field of study and practice.