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Principles of Heart Valve Engineering

Principles of Heart Valve Engineering
  • Author : Arash Kheradvar
  • Publisher :Unknown
  • Release Date :2019-08-28
  • Total pages :414
  • ISBN : 9780128146620
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Summary : Principles of Heart Valve Engineering is the first comprehensive resource for heart valve engineering that covers a wide range of topics, including biology, epidemiology, imaging and cardiovascular medicine. It focuses on valves, therapies, and how to develop safer and more durable artificial valves. The book is suitable for an interdisciplinary audience, with contributions from bioengineers and cardiologists that includes coverage of valvular and potential future developments. This book provides an opportunity for bioengineers to study all topics relating to heart valve engineering in a single book as written by subject matter experts. Covers the depth and breadth of this interdisciplinary area of research Encompasses a wide range of topics, from basic science, to the translational applications of heart valve engineering Contains contributions from leading experts in the field that are heavily illustrated

The Mechanics of Trans-Catheter and Surgical Heart Valves

The Mechanics of Trans-Catheter and Surgical Heart Valves
  • Author : Lakshmi Dasi,Lakshmi Prasad Dasi,Hoda Hatoum
  • Publisher :Unknown
  • Release Date :2020-06
  • Total pages :350
  • ISBN : 0128145544
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Summary : The Mechanics of Transcatheter and Surgical Heart Valves: A Guide for Engineers and Clinicians focuses on the fundamental principles of heart valve mechanics, providing a detailed picture of the pros and cons of current devices in the context of their biomechanics, biomaterials, patient complications, and their regulatory and fabrication aspects. The book covers methods and applications that will help readers innovate and design new cardiovascular technology. It is ideal for designers, testers and manufacturers, anyone working in the biomaterials industry on coatings or fabrication materials, or those researching mechanics and heart valve biology. Covers fluid mechanics, solid mechanics and biomaterials concepts Provides the only book on the market to offer this depth of information on prosthetic heart valves Includes flow visualization videos and high-speed valve imaging videos

Principles of Tissue Engineering

Principles of Tissue Engineering
  • Author : Robert Lanza,Robert Langer,Joseph P. Vacanti
  • Publisher :Unknown
  • Release Date :2000-05-16
  • Total pages :995
  • ISBN : 9780080539676
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Summary : The opportunity that tissue engineering provides for medicine is extraordinary. In the United States alone, over half-a-trillion dollars are spent each year to care for patients who suffer from tissue loss or dysfunction. Although numerous books and reviews have been written on tissue engineering, none has been as comprehensive in its defining of the field. Principles of Tissue Engineering combines in one volume the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation of applications of tissue engineering to diseases affecting specific organ systems. The first edition of the book, published in 1997, is the definite reference in the field. Since that time, however, the discipline has grown tremendously, and few experts would have been able to predict the explosion in our knowledge of gene expression, cell growth and differentiation, the variety of stem cells, new polymers and materials that are now available, or even the successful introduction of the first tissue-engineered products into the marketplace. There was a need for a new edition, and this need has been met with a product that defines and captures the sense of excitement, understanding and anticipation that has followed from the evolution of this fascinating and important field. Key Features * Provides vast, detailed analysis of research on all of the major systems of the human body, e.g., skin, muscle, cardiovascular, hematopoietic, and nerves * Essential to anyone working in the field * Educates and directs both the novice and advanced researcher * Provides vast, detailed analysis of research with all of the major systems of the human body, e.g. skin, muscle, cardiovascular, hematopoietic, and nerves * Has new chapters written by leaders in the latest areas of research, such as fetal tissue engineering and the universal cell * Considered the definitive reference in the field * List of contributors reads like a "who's who" of tissue engineering, and includes Robert Langer, Joseph Vacanti, Charles Vacanti, Robert Nerem, A. Hari Reddi, Gail Naughton, George Whitesides, Doug Lauffenburger, and Eugene Bell, among others

Calcific Aortic Valve Disease

Calcific Aortic Valve Disease
  • Author : Elena Aikawa
  • Publisher :Unknown
  • Release Date :2013-06-12
  • Total pages :542
  • ISBN : 9789535111504
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Summary : Due to population aging, calcific aortic valve disease (CAVD) has become the most common heart valve disease in Western countries. No therapies exist to slow this disease progression, and surgical valve replacement is the only effective treatment. Calcific Aortic Valve Disease covers the contemporary understanding of basic valve biology and the mechanisms of CAVD, provides novel insights into the genetics, proteomics, and metabolomics of CAVD, depicts new strategies in heart valve tissue engineering and regenerative medicine, and explores current treatment approaches. As we are on the verge of understanding the mechanisms of CAVD, we hope that this book will enable readers to comprehend our current knowledge and focus on the possibility of preventing disease progression in the future.

Principles of Tissue Engineering

Principles of Tissue Engineering
  • Author : Robert Lanza,Robert Langer,Joseph P. Vacanti
  • Publisher :Unknown
  • Release Date :2011-10-13
  • Total pages :1344
  • ISBN : 0080548849
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Summary : First published in 1997, Principles of Tissue Engineering is the widely recognized definitive resource in the field. The third edition provides a much needed update of the rapid progress that has been achieved in the field, combining the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation by the world’s experts of what is currently known about each specific organ system. This edition includes greatly expanded focus on stem cells, including adult and embryonic stem cells and progenitor populations that may soon lead to new tissue engineering therapies for heart disease, diabetes, and a wide variety of other diseases that afflict humanity. This up-to-date coverage of stem cell biology and other emerging technologies is complemented by a series of new chapters on recent clinical experience in applying tissue engineering. The result is a comprehensive textbook that we believe will be useful to students and experts alike. New to this edition: *Includes new chapters on biomaterial-protein interactions, nanocomposite and three-dimensional scaffolds, skin substitutes, spinal cord, vision enhancement, and heart valves *Expanded coverage of adult and embryonic stem cells of the cardiovascular, hematopoietic, musculoskeletal, nervous, and other organ systems

Cardiovascular Mechanics

Cardiovascular Mechanics
  • Author : Michel R. Labrosse
  • Publisher :Unknown
  • Release Date :2018-09-13
  • Total pages :386
  • ISBN : 9781315280288
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Summary : The objective of this book is to illustrate in specific detail how cardiovascular mechanics stands as a common pillar supporting such different clinical successes as drugs for high blood pressure, prosthetic heart valves and coronary artery bypass grafting, among others. This information is conveyed through a comprehensive treatment of the overarching principles and theories that are behind mechanobiological processes, aortic and arterial mechanics, atherosclerosis, blood and microcirculation, hear valve mechanics, as well as medical devices and drugs. Examines all major theoretical and practical aspects of mechanical forces related to the cardiovascular system. Discusses a unique coverage of mechanical changes related to an aging cardiovascular system. Provides an overview of experimental methods in cardiovascular mechanics. Written by world-class researchers from Canada, the US and EU. Extensive references are provided at the end of each chapter to enhance further study. Michel R. Labrosse is the founder of the Cardiovascular Mechanics Laboratory at the University of Ottawa, where he is a full professor within the Department of Mechanical Engineering. He has been an active researcher in academia along with being heavily associated with the University of Ottawa Heart Institute. He has authored or co-authored over 90 refereed communications, and supervised or co-supervised over 40 graduate students and post-docs.

Biofluid Mechanics

Biofluid Mechanics
  • Author : Ali Ostadfar
  • Publisher :Unknown
  • Release Date :2016-06-03
  • Total pages :382
  • ISBN : 9780128026007
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Summary : Biofluid Mechanics is a throrough reference to the entire field. Written with engineers and clinicians in mind, this book covers physiology and the engineering aspects of biofluids. Effectively bridging the gap between engineers’ and clinicians’ knowledge bases, the text provides information on physiology for engineers and information on the engineering side of biofluid mechanics for clinicians. Clinical applications of fluid mechanics principles to fluid flows throughout the body are included in each chapter. All engineering concepts and equations are developed within a biological context, together with computational simulation examples as well. Content covered includes; engineering models of human blood, blood rheology in the circulation system and problems in human organs and their side effects on biomechanics of the cardiovascular system. The information contained in this book on biofluid principles is core to bioengineering and medical sciences. Comprehensive coverage of the entire biofluid mechanics subject provides you with an all in one reference, eliminating the need to collate information from different sources Each chapter covers principles, needs, problems, and solutions in order to help you identify potential problems and employ solutions Provides a novel breakdown of fluid flow by organ system, and a quick and focused reference for clinicians

Advanced Concepts in Endocarditis

Advanced Concepts in Endocarditis
  • Author : Michael S. Firstenberg
  • Publisher :Unknown
  • Release Date :2018-09-12
  • Total pages :200
  • ISBN : 9781789236262
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Summary :

Bioreactors for Tissue Engineering

Bioreactors for Tissue Engineering
  • Author : Julian Chaudhuri,Mohamed Al-Rubeai
  • Publisher :Unknown
  • Release Date :2006-01-16
  • Total pages :376
  • ISBN : 9781402037412
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Summary : For the first time in a single volume, the design, characterisation and operation of the bioreactor system in which the tissue is grown is detailed. Bioreactors for Tissue Engineering presents an overall picture of the current state of knowledge in the engineering of bioreactors for several tissue types (bone, cartilage, vascular), addresses the issue of mechanical conditioning of the tissue, and describes the use of techniques such as MRI for monitoring tissue growth. This unique volume is dedicated to the fundamentals and application of bioreactor technology to tissue engineering products. Not only will it appeal to graduate students and experienced researchers in tissue engineering and regenerative medicine, but also to tissue engineers and culture technologists, academic and industrial chemical engineers, biochemical engineers and cell biologists who wish to understand the criteria used to design and develop novel systems for tissue growth in vitro.

Encyclopedia of Biomaterials and Biomedical Engineering

Encyclopedia of Biomaterials and Biomedical Engineering
  • Author : Gary E. Wnek,Gary L. Bowlin
  • Publisher :Unknown
  • Release Date :2008-05-28
  • Total pages :3552
  • ISBN : 9781498761437
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Summary : Written by more than 400 subject experts representing diverse academic and applied domains, this multidisciplinary resource surveys the vanguard of biomaterials and biomedical engineering technologies utilizing biomaterials that lead to quality-of-life improvements. Building on traditional engineering principles, it serves to bridge advances in mat

Biomedical Engineering Principles

Biomedical Engineering Principles
  • Author : Stanley Reisman,Arthur B. Ritter,Vikki Hazelwood,Bozena B. Michniak,Antonio Valdevit,Alfred N. Ascione
  • Publisher :Unknown
  • Release Date :2018-11-07
  • Total pages :680
  • ISBN : 9780849338595
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Summary : The updated edition of this popular textbook offers an overview of the major components of the field, including signal processing in bio-systems, biomechanics, and biomaterials. Introducing capstone design and entrepreneurship, the second edition examines basic engineering, anatomy, and physiology concepts to facilitate an in-depth and up

Structural Insufficiency Anomalies in Cardiac Valves

Structural Insufficiency Anomalies in Cardiac Valves
  • Author : Kaan Kirali
  • Publisher :Unknown
  • Release Date :2018-10-03
  • Total pages :162
  • ISBN : 9781789237665
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Summary :

Biomedical Engineering Principles

Biomedical Engineering Principles
  • Author : Arthur B. Ritter,Vikki Hazelwood,Antonio Valdevit,Alfred N. Ascione
  • Publisher :Unknown
  • Release Date :2011-05-24
  • Total pages :540
  • ISBN : 9781439812334
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Summary : Current demand in biomedical sciences emphasizes the understanding of basic mechanisms and problem solving rather than rigid empiricism and factual recall. Knowledge of the basic laws of mass and momentum transport as well as model development and validation, biomedical signal processing, biomechanics, and capstone design have indispensable roles in the engineering analysis of physiological processes. To this end, an introductory, multidisciplinary text is a must to provide the necessary foundation for beginning biomedical students. Assuming no more than a passing acquaintance with molecular biology, physiology, biochemistry, and signal processing, Biomedical Engineering Principles, Second Edition provides just such a solid, accessible grounding to this rapidly advancing field. Acknowledging the vast range of backgrounds and prior education from which the biomedical field draws, the organization of this book lends itself to a tailored course specific to the experience and interests of the student. Divided into four sections, the book begins with systems physiology, transport processes, cell physiology, and the cardiovascular system. Part I covers systems analysis, biological data, and modeling and simulation in experimental design, applying concepts of diffusion, and facilitated and active transport. Part II presents biomedical signal processing, reviewing frequency, periodic functions, and Fourier series as well as signal acquisition and processing techniques. Part III presents the practical applications of biomechanics, focusing on the mechanical and structural properties of bone, musculoskeletal, and connective tissue with respect to joint range, load bearing capacity, and electrical stimulation. The final part highlights capstone design, discussing design perspectives for living and nonliving systems, the role of the FDA, and the project timeline from inception to proof of concept. Cutting across many disciplines, Biomedical Engineering Principles, Second Edition offers illustrative examples as well as problems and discussion questions designed specifically for this book to provide a readily accessible, widely applicable introductory text.

Advanced Cardiac Imaging

Advanced Cardiac Imaging
  • Author : Koen Nieman,Oliver Gaemperli,Patrizio Lancellotti,Sven Plein
  • Publisher :Unknown
  • Release Date :2015-07-16
  • Total pages :804
  • ISBN : 9781782422945
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Summary : Advances in Cardiac Imaging presents the latest information on heart disease and heart failure, major causes of death among western populations. In addition, the text explores the financial burden to public healthcare trusts and the vast amount of research and funding being channeled into programs not only to prevent such diseases, but also to diagnose them in early stages. This book provides readers with a thorough overview of many advances in cardiac imaging. Chapters include technological developments in cardiac imaging and imaging applications in a clinical setting with regard to detecting various types of heart disease. Presents a thorough overview of cardiac imaging technology Addresses specific applications for a number of cardiac diseases and how they can improve diagnoses and treatment protocols Includes technological developments in cardiac imaging and imaging applications in a clinical setting

Biomaterials Science

Biomaterials Science
  • Author : Buddy D. Ratner,Allan S. Hoffman,Frederick J. Schoen,Jack E. Lemons
  • Publisher :Unknown
  • Release Date :2004-08-18
  • Total pages :864
  • ISBN : 9780080470368
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Summary : The second edition of this bestselling title provides the most up-to-date comprehensive review of all aspects of biomaterials science by providing a balanced, insightful approach to learning biomaterials. This reference integrates a historical perspective of materials engineering principles with biological interactions of biomaterials. Also provided within are regulatory and ethical issues in addition to future directions of the field, and a state-of-the-art update of medical and biotechnological applications. All aspects of biomaterials science are thoroughly addressed, from tissue engineering to cochlear prostheses and drug delivery systems. Over 80 contributors from academia, government and industry detail the principles of cell biology, immunology, and pathology. Focus within pertains to the clinical uses of biomaterials as components in implants, devices, and artificial organs. This reference also touches upon their uses in biotechnology as well as the characterization of the physical, chemical, biochemical and surface properties of these materials. Provides comprehensive coverage of principles and applications of all classes of biomaterials Integrates concepts of biomaterials science and biological interactions with clinical science and societal issues including law, regulation, and ethics Discusses successes and failures of biomaterials applications in clinical medicine and the future directions of the field Cover the broad spectrum of biomaterial compositions including polymers, metals, ceramics, glasses, carbons, natural materials, and composites Endorsed by the Society for Biomaterials

The Aortic Valve

The Aortic Valve
  • Author : ManoJ. Thubrikar
  • Publisher :Unknown
  • Release Date :2018-05-04
  • Total pages :232
  • ISBN : 9781351411400
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Summary : This book provides information on the aortic valve. Written in a comprehensive style, it emphasizes the principles behind the development of artificial valves. It covers the principles of valve geometry, tissue structure and function relationships, valve dynamics, fluid dynamics, mechanical stresses, echocardiographic images, mechanisms of valve sounds, valvular pathology, and design and performance of bioprosthetic valves. It enhances our understanding of angiographic and echocardiographic images and calcific stenosis, and will be of value in the development of better prostheses. The Aortic Valve is the ideal text for biomedical engineers and a unique resource for teaching interdisciplinary approaches to medical and engineering students. This work is also an indispensible source for cardiac surgeons, pathologists, cardiologists, and manufacturers of prosthetic valves.

Biofluid Mechanics

Biofluid Mechanics
  • Author : David A. Rubenstein,Mary D. Frame,Wei Yin
  • Publisher :Unknown
  • Release Date :2012
  • Total pages :400
  • ISBN : 9780123813831
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Summary : Both broad and deep in coverage, Rubenstein shows that fluid mechanics principles can be applied not only to blood circulation, but also to air flow through the lungs, joint lubrication, intraocular fluid movement and renal transport. Each section initiates discussion with governing equations, derives the state equations and then shows examples of their usage. Clinical applications, extensive worked examples, and numerous end of chapter problems clearly show the applications of fluid mechanics to biomedical engineering situations. A section on experimental techniques provides a springboard for future research efforts in the subject area. Uses language and math that is appropriate and conducive for undergraduate learning, containing many worked examples and end of chapter problems All engineering concepts and equations are developed within a biological context Covers topics in the traditional biofluids curriculum, as well as addressing other systems in the body that can be described by biofluid mechanics principles, such as air flow through the lungs, joint lubrication, intraocular fluid movement, and renal transport Clinical applications are discussed throughout the book, providing practical applications for the concepts discussed.

Operative Cardiac Surgery

Operative Cardiac Surgery
  • Author : Thomas L. Spray,Michael A. Acker
  • Publisher :Unknown
  • Release Date :2018-09-03
  • Total pages :788
  • ISBN : 9781351175968
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Summary : The sixth edition of this acclaimed and established operative atlas continues to provide a unique level of comprehensive detail on operative surgery of the heart and great vessels. With an international list of authors, the chapters have been updated and complemented by the same high quality artwork that has established this operative guide as the gold standard reference for the cardiac surgeon. This new edition retains the format of initial principles and justification for the procedure, followed by preoperative investigations and preparation, the operative procedure, and postoperative management. New chapters have been added on the latest techniques such as minimal invasive surgery, robotic surgery and off-pump bypass surgery. The chapters are arranged in seven sections, with each section emphasising the overall management of patients, tricks of the trade of individual authors and discussion of technical and clinical judgement. With this new and updated edition, Operative Cardiac Surgery remains the pre-eminent operative guide to a full range of cardiac conditions. Video clips of cardiac procedures, both common and rare, are included within the VitalSource edition. Print Versions of this book also include access to the ebook version.

Animals and Medicine

Animals and Medicine
  • Author : Jack Botting
  • Publisher :Unknown
  • Release Date :2015-05-04
  • Total pages :244
  • ISBN : 9781783741175
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Summary : Animals and Medicine: The Contribution of Animal Experiments to the Control of Disease offers a detailed, scholarly historical review of the critical role animal experiments have played in advancing medical knowledge. Laboratory animals have been essential to this progress, and the knowledge gained has saved countless lives—both human and animal. Unfortunately, those opposed to using animals in research have often employed doctored evidence to suggest that the practice has impeded medical progress. This volume presents the articles Jack Botting wrote for the Research Defence Society News from 1991 to 1996, papers which provided scientists with the information needed to rebut such claims. Collected, they can now reach a wider readership interested in understanding the part of animal experiments in the history of medicine—from the discovery of key vaccines to the advancement of research on a range of diseases, among them hypertension, kidney failure and cancer.This book is essential reading for anyone curious about the role of animal experimentation in the history of science from the nineteenth century to the present.

Core Topics in Cardiac Anesthesia

Core Topics in Cardiac Anesthesia
  • Author : Jonathan H. Mackay,Joseph E. Arrowsmith
  • Publisher :Unknown
  • Release Date :2012-03-15
  • Total pages :492
  • ISBN : 9780521196857
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Summary : Since the publication of the first edition of Core Topics in Cardiac Anesthesia, the clinical landscape has undergone significant change. Recent developments include the increased use of electrophysiology, the resurgence of primary percutaneous intervention in acute coronary syndromes, the use of percutaneous devices in patients previously considered inoperable, and the withdrawal of aprotinin. Against this landscape, this invaluable resource has been fully updated. New chapters are dedicated to right heart valves, pulmonary vascular disease, cardiac tumours and cardiac trauma. All other chapters have been updated according to the latest international guidelines. Written and edited by an international author team with a wealth of expertise in all aspects of the perioperative care of cardiac patients, topics are presented in an easy to digest and a readily accessible manner. Core Topics in Cardiac Anesthesia, Second Edition is essential reading for residents and fellows in anesthesia and cardiac surgery and clinical perfusionists.

Biomaterials Science

Biomaterials Science
  • Author : William R Wagner,Shelly E. Sakiyama-Elbert,Guigen Zhang,Michael J. Yaszemski
  • Publisher :Unknown
  • Release Date :2020-05-23
  • Total pages :1616
  • ISBN : 9780128161388
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Summary : The revised edition of the renowned and bestselling title is the most comprehensive single text on all aspects of biomaterials science from principles to applications. Biomaterials Science, fourth edition, provides a balanced, insightful approach to both the learning of the science and technology of biomaterials and acts as the key reference for practitioners who are involved in the applications of materials in medicine. This new edition incorporates key updates to reflect the latest relevant research in the field, particularly in the applications section, which includes the latest in topics such as nanotechnology, robotic implantation, and biomaterials utilized in cancer research detection and therapy. Other additions include regenerative engineering, 3D printing, personalized medicine and organs on a chip. Translation from the lab to commercial products is emphasized with new content dedicated to medical device development, global issues related to translation, and issues of quality assurance and reimbursement. In response to customer feedback, the new edition also features consolidation of redundant material to ensure clarity and focus. Biomaterials Science, 4th edition is an important update to the best-selling text, vital to the biomaterials’ community. The most comprehensive coverage of principles and applications of all classes of biomaterials Edited and contributed by the best-known figures in the biomaterials field today; fully endorsed and supported by the Society for Biomaterials Fully revised and updated to address issues of translation, nanotechnology, additive manufacturing, organs on chip, precision medicine and much more. Online chapter exercises available for each chapter