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Sertoli Cell Biology

Sertoli Cell Biology
  • Author : Michael D. Griswold
  • Publisher :Unknown
  • Release Date :2014-11-19
  • Total pages :488
  • ISBN : 9780124170483
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Summary : Sertoli Cell Biology, Second Edition summarizes the progress since the last edition and emphasizes the new information available on Sertoli/germ cell interactions. This information is especially timely since the progress in the past few years has been exceptional and it relates to control of sperm production in vivo and in vitro. Fully revised Written by experts in the field Summarizes 10 years of research Contains clear explanations and summaries Provides a summary of references over the last 10 years

Exam Prep for: Sertoli Cell Biology

Exam Prep for: Sertoli Cell Biology
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2021
  • Total pages :229
  • ISBN : 1230987654XX
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Summary :

Sertoli Cell Metabolism and Spermatogenesis

Sertoli Cell Metabolism and Spermatogenesis
  • Author : Pedro F. Oliveira,Marco G. Alves
  • Publisher :Unknown
  • Release Date :2015-11-29
  • Total pages :98
  • ISBN : 9783319197913
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Summary : This book is focused on Sertoli cell physiology and its role in the spermatogenic event. These cells, known as “nurse cells”, are essential for the normal development of germ cells by offering not only physical support and creating an immune-privileged environment, but also for providing nutritional support. The presence of Sertoli cells promotes the establishment of the appropriate microenvironment so that spermatogenesis may occur. Spermatogenesis maintenance in vivo is highly dependent on the metabolic cooperation established between Sertoli cells and developing germ cells. For many years this metabolic cooperation between testicular cells has been disregarded, but recent advances have highlighted the relevance of these processes for male fertility. Thus, the understanding of the functioning and regulation of these metabolic processes is a crucial step to identify key mechanisms associated with Sertoli cell (dys)function and to enlighten their influence on male fertility.

The Sertoli Cell

The Sertoli Cell
  • Author : Lonnie Dee Russell,Michael D. Griswold
  • Publisher :Unknown
  • Release Date :1993
  • Total pages :801
  • ISBN : UOM:39015029281964
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Summary :

Sertoli Cells

Sertoli Cells
  • Author : Marco G. Alves,Pedro F. Oliveira
  • Publisher :Unknown
  • Release Date :2019-06-06
  • Total pages :297
  • ISBN : 1493985434
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Summary : This detailed volume explores the use of Sertoli cells as models in male reproductive biology or as supporters for other cell types, and it answers the need for standardized protocols for their in vitro culture. Prepared for non-specialists as well as experienced researchers that may be interested in a multidisciplinary approach to study these cells, the book examines these remarkable cells that present some unique features that go far beyond the physical and nutritional support of spermatogenesis. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Sertoli Cells: Methods and Protocols serves as a valuable resource for experienced researchers in reproductive biology, particularly andrologists, but also for future investigators and young students starting to study these extraordinary cells.

Molecular Mechanisms in Spermatogenesis

Molecular Mechanisms in Spermatogenesis
  • Author : C.Y. Cheng
  • Publisher :Unknown
  • Release Date :2009-10-24
  • Total pages :274
  • ISBN : 0387095977
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Summary : In the past thirty years, significant advances have been made in the field of reproductive biology in unlocking the molecular and biochemical events that regulate spermatogenesis in the mammalian testis. It was possible because of the unprecedented breakthroughs in molecular biology, cell biology, immunology, and biochemistry. In this book entitled, Molecular Mechanisms in Spermatogenesis, a collection of chapters has been included written by colleagues on the latest development in the field using genomic and proteomic approaches to study spermatogenesis, as well as different mechanisms and/or molecules including environmental toxicants and transcription factors that regulate and/or affect spermatogenesis. The book begins with a chapter that provides the basic concept of cellular regulation of spermatogenesis. A few chapters are also dedicated to some of the latest findings on the Sertoli cell cytoskeleton and other molecules (e.g., proteases, adhesion proteins) that regulate spermatogenesis. These chapters contain thought-provoking discussions and concepts which shall be welcomed by investigators in the field. It is obvious that many of these concepts will be updated and some may be amended in the years to come. However, they will serve as a guide and the basis for investigation by scientists in the field.

Cell and Molecular Biology of the Testis

Cell and Molecular Biology of the Testis
  • Author : Des Jardins
  • Publisher :Unknown
  • Release Date :1993
  • Total pages :497
  • ISBN : 0195062698
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Summary : This book is a comprehensive, multi-authored work on the structure and function of the mammalian testis. The approach emphasizes gene expression, translation and production of specific gene products and the cellular and molecular regulation of these fundamental processes. Rather than provide a global survey of all aspects of male reproduction, this book stresses specific mechanisms that underscore the structure and function of the testis. It explains old and new concepts from a cellular and molecular perspective. This novel approach allows the authors to forge links between cell and molecular biology and well-established aspects of spermatogenesis and steroidogenesis. The result is a well-focused, comprehensive, and synthetic analysis of testicular biology.

Activins and Inhibins

Activins and Inhibins
  • Author : Gerald Litwack
  • Publisher :Unknown
  • Release Date :2011
  • Total pages :349
  • ISBN : 9780123859617
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Summary : First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines. This volume focuses on activins and inhibins.

The Y Chromosome and Male Germ Cell Biology in Health and Diseases

The Y Chromosome and Male Germ Cell Biology in Health and Diseases
  • Author : Yun-Fai Lau
  • Publisher :Unknown
  • Release Date :2007
  • Total pages :314
  • ISBN : 9789812770431
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Summary : The completion of the human genome and technological advances developed by the Human Genome Project have dramatically changed our understanding of the mechanisms underlying the development and differentiation of male germ cells, and our ability to investigate such mechanisms. This book is a timely document of advances made in the field of male gonad and germ cell research in the postgenomic era. The coverage includes the role of Y chromosome genes in male reproduction, gene expression in spermatogonial stem cells and male germ cells, and the regulation of germ cell genes in reproduction and in germ cell tumors.

Molecular Mechanisms of Cell Differentiation in Gonad Development

Molecular Mechanisms of Cell Differentiation in Gonad Development
  • Author : Rafal P. Piprek
  • Publisher :Unknown
  • Release Date :2016-06-14
  • Total pages :434
  • ISBN : 9783319319735
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Summary : This book presents the current state of knowledge on the origin and differentiation of cell lines involved in the development of the vertebrate male and female gonads with particular emphasis on the mouse. It also discusses the processes leading to the testis- and ovary-specific structures and functions. The individual chapters review the origin and differentiation of the somatic cells of the genital ridges; the formation and migration of primordial germ cells in mouse and man; the gonadal supporting cell lineage and mammalian sex determination; differentiation of Sertoli and granulosa cells; mesonephric cell migration into the gonads and vascularization; origin and differentiation of androgen-producing cells in the gonads; germ cell commitment to the oogenic versus spermatogenic pathway and the role of retinoic acid; ovarian folliculogenesis; control of oocyte growth and development by intercellular communication within the follicular niche; biology of the Sertoli cell in the fetal, pubertal and adult mammalian testis; mechanisms regulating spermatogonial differentiation; stem cells in mammalian gonads; the role of microRNAs in cell differentiation during gonad development; human sex development and its disorders; as well as methods for the study of gonadal development.

Molecular Biology of the Male Reproductive System

Molecular Biology of the Male Reproductive System
  • Author : David de Kretser
  • Publisher :Unknown
  • Release Date :2012-12-02
  • Total pages :483
  • ISBN : 9780080917641
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Summary : Written by experts in their respective fields, this book reviews the expanding knowledge concerning the mechanisms regulating male reproduction at the molecular and cellular levels. It covers the development of the testes and regulatory controls for spermatogenesis and steroidogenesis, and it considers aspects of Sertoli cell function. Areas of emphasis include communication between the various cell types involved in reproduction by hormone and growth factors and the mechanisms by which these factors regulate gene expression. A number of mammalian systems, including humans, are covered. The carefully selected authors provide a clear synopsis of the concepts in each area as well as the latest references, enabling the reader to investigate the topic further. This book is of interest to those seeking an understanding of the regulatory mechanisms in male reproduction and is written for the graduate and postgraduate levels. Key Features * Provides up-to-date reviews of the molecular and cellular biology of male reproduction * Includes chapters on the developmental biology of the testes * Links conventional hormonal control of testicular function with the evolving role of growth factors and proto-oncogenes

Spermatogenesis

Spermatogenesis
  • Author : C. Yan Cheng
  • Publisher :Unknown
  • Release Date :2018-09-03
  • Total pages :278
  • ISBN : 9780429949494
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Summary : Senior investigators internationally have here collaborated to produce an international reference work. Each contributor provides critical and thought provoking concepts and ideas based on the latest developments in their field. The result is a must read and timely reference work for investigators who are interested in how spermatogenesis is currently understood and which are the most promising avenues for future research; an Introduction sets the context for the chapter and points out the relevance of the research for basic research scientists and clinicians.

Ultrastructure of Reproduction

Ultrastructure of Reproduction
  • Author : Jonathan van Blerkom,P. Motta
  • Publisher :Unknown
  • Release Date :2012-12-06
  • Total pages :290
  • ISBN : 9781461338673
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Summary : Advances in the development and application of electron microscopic techniques have occurred recently such that the electron microscope has evolved to become an essential tool in both basic and clinical research. Use of this instrument has contributed significantly to the formation of new perspectives and concepts concerning cell fine structure. These structural perspectives are now being integrated with specific functional, biochemical and pathophysiological events and processes of cells and tissues. Most recently, utilization of innovative electron microscopic techniques such as freeze-fracture, freeze etching, and scanning and high-voltage electron microscopy offers both the basic and clinical scientist potentially fundamental insights into many morphodynamic processes related to the activities of cells and tissues. Such an approach has been especially rewarding when applied to the dynamic events of gametogenesis and early embryonic development. The chapters comprising this book have been selected and edited with the aim of providing an up-to-date and comprehensive account of the most important aspects of vertebrate gamets and embryos as revealed by the integration of several different submicroscopic methods. The organization of the chapters is designed to indicate present gaps in our knowledge of the developmental and reproductive biology of gametes and the developing embryo and possible Iines of research which may lead to a lessening of these gaps.

The Neuroendocrine Leydig Cells and their Stem Cell Progenitors, the Pericytes

The Neuroendocrine Leydig Cells and their Stem Cell Progenitors, the Pericytes
  • Author : Michail S. Davidoff,Ralf Middendorff,D. Müller,Adolf F. Holstein
  • Publisher :Unknown
  • Release Date :2009-07-15
  • Total pages :154
  • ISBN : 3642005136
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Summary : cells, and the testicular localization of the intermediate filament protein nestin, known to be expressed in neural stem cells, by our group was the first step to define mural cells (pericytes and vascular smooth muscle cells) of the testis microvascu- ture as the stem/progenitor cells of the adult Leydig cells. In summary, we were able to demonstrate specific proliferation of vascular progenitors and their subsequent transdifferentiation into steroidogenic Leydig cells, which – in addition – rapidly acquire neuronal and glial properties. Since both newly developed fetal and adult Leydig cell populations show the same features, a common origin of both popu- tions seems likely. Pericytes are distributed throughout the body, and there is convincing evidence for their stem/progenitor cell properties in diverse organs. Under appropriate (locally defined) conditions these pericytes, which reside in the vascular stem cell niche as dormant stem cells, become activated, proliferate, migrate and differentiate towards different somatic cell types of the body. Since most mesenchymal stem/ progenitor cell types exhibit essential similarity to pericytes and certain mesenchymal stem cells represent pericyte descendants, we propose that mesenchymal stem cells in the perivascular niche are daughter cells of pericytes. Thus, pericytes are promising candidates for ancestor cells of all adult stem cells in the organism. There is strong evidence that early stem cells (cells arising during embryogenesis), such as the pericytes, exhibit both mesodermal and neural progeny, which might explain the neuroendocrine properties of the Leydig cells.

The Cell Biology of the Testis

The Cell Biology of the Testis
  • Author : C. Wayne Bardin,Richard J. Sherins
  • Publisher :Unknown
  • Release Date :1982
  • Total pages :543
  • ISBN : 0897661818
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Summary :

Cell Biology

Cell Biology
  • Author : Julio E. Celis,Julio E.. Celis
  • Publisher :Unknown
  • Release Date :1998
  • Total pages :563
  • ISBN : UOM:39015040079751
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Summary : V. 1: cell and tissue culture and associated techniques; Primary cultures from embyonic and newborn tissues; Culture of specific cell types; Cell separation techniques; Model systems to study differentiation; cell cycle analysis; Assays of tumorigenicity, invasion, and others; Cytotoxic and cell growth assays; Senescence and apoptosis; Electrophysiological methods; Histocultures and organ cultures; Other cell types and organisms; Viruses; Appendices; v. 2: Organelles and cellular structures; Assays; Antibodies; Immunocytochemistry; Vital staining of cells; v. 3: Light microscopy and contrast generation; Electron microscopy; Intracellular measurments; Cytogenetics and in situ hybridization; transgenic and gene knockouts; v. 4: Transfer of macromelcules and small molecules; Expression systems; Differential gene expression; Proteins; Appendix; List of suppliers; Subject index.

The Leydig Cell in Health and Disease

The Leydig Cell in Health and Disease
  • Author : Anita H. Payne,Matthew P. Hardy
  • Publisher :Unknown
  • Release Date :2007-10-28
  • Total pages :476
  • ISBN : 9781597454537
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Summary : This book provides a comprehensive study of the Leydig cell, a fascinating and important cell type. It presents all of the developments in our understanding of Leydig cell biology and explores a wide variety of current and potential clinical applications. All aspects of Leydig cell biology, development, regulation, and physiology are explored in thirty-one expertly written chapters. This in-depth volume is an invaluable resource.

Molecular Biology of the Cell

Molecular Biology of the Cell
  • Author : Bruce Alberts
  • Publisher :Unknown
  • Release Date :2004
  • Total pages :229
  • ISBN : 0815332181
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Summary :

Spermatozoa

Spermatozoa
  • Author : Rosaria Meccariello,Rosanna Chianese
  • Publisher :Unknown
  • Release Date :2018-06-13
  • Total pages :250
  • ISBN : 9781789231700
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Summary : Spermatozoa, the haploid male gametes, are highly specialized cells capable to fertilize eggs in order to produce diploid zygote. The biogenesis of spermatozoa requires finely modulated occurrence of mitotic, meiotic, and differentiation events. Hence, the production of high-quality spermatozoa impacts fertilization with outcomes on the health of the offspring. This book provides a comprehensive overview on the biogenesis, maturation, functions and activities of spermatozoa in both physiological conditions and infertility. Particular attention has been addressed to the impact of environment on sperm quality and to the appropriate selection of high-quality spermatozoa for in vitro fertilization. Taken together, this book targets a wide audience of basic and clinical scientists, teachers and students, and offers a better understanding of spermatozoa health and disease.

The Testis

The Testis
  • Author : Henry G. Burger,David M. De Kretser
  • Publisher :Unknown
  • Release Date :1981
  • Total pages :442
  • ISBN : UOM:39015000853088
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Summary :

Biochemistry and Cell Biology

Biochemistry and Cell Biology
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2001
  • Total pages :229
  • ISBN : UIUC:30112054031965
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Summary :