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Sex and Gender Differences in Alzheimer's Disease

Sex and Gender Differences in Alzheimer's Disease
  • Author : Maria Teresa Ferretti,Annemarie Schumacher Dimech,Antonella Chadha Santuccione
  • Publisher :Unknown
  • Release Date :2021-05-15
  • Total pages :301
  • ISBN : 0128193441
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Summary : Sex and Gender Differences in Alzheimer's Disease: The Women's Brain Project offers, for the first time, a critical overview of the evidence documenting sex and gender differences in AD neurobiology, biomarkers, clinical presentation, treatment, clinical trials and their outcomes and impact on caregivers. This knowledge is crucial for clinical development, digital health solutions, and as social and psychological support to AD families. Presents comprehensive and critical reviews of sex differences in Alzheimer's disease Combines the knowledge and points-of-view of neuroscientists, medical doctors, psychologists and AI experts for a 360 degree view on the topic and its possible implications Edited by the Women's Brain Project, the leading NGO in the field of sex differences in neuroscience

Exploring the Biological Contributions to Human Health

Exploring the Biological Contributions to Human Health
  • Author : Institute of Medicine,Board on Health Sciences Policy,Committee on Understanding the Biology of Sex and Gender Differences
  • Publisher :Unknown
  • Release Date :2001-07-02
  • Total pages :288
  • ISBN : 0309132975
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Summary : It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers.

Sex Hormones in Neurodegenerative Processes and Diseases

Sex Hormones in Neurodegenerative Processes and Diseases
  • Author : Gorazd Drevensek
  • Publisher :Unknown
  • Release Date :2018-05-02
  • Total pages :358
  • ISBN : 9781789230147
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Summary : The book provides chapters on sex hormones and their modulation in neurodegenerative processes and pathologies, from basic molecular mechanisms, physiology, gender differences, to neuroprotection and clinical aspects for potential novel pharmacotherapy approaches. The book contains 14 chapters written by authors from various biomedical professions, from basic researchers in biology and physiology to medicine and veterinary medicine, pharmacologists, psychiatrist, etc. Chapters sum up the past and current knowledge on sex hormones, representing original new insights into their role in brain functioning, mental disorders and neurodegenerative diseases. The book is written for a broad range of audience, from biomedical students to highly profiled medical specialists and biomedical researchers, helping them to expand their knowledge on sex hormones in neurodegenerative processes and opening new questions for further investigation.

Sex Differences in Neurology and Psychiatry

Sex Differences in Neurology and Psychiatry
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2020-09-30
  • Total pages :476
  • ISBN : 9780444641243
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Summary : Sex Differences in Neurology and Psychiatry, Volume 175, addresses this important issue by viewing major neurological and psychiatric conditions through the lens of sexual dimorphism, providing an entirely novel approach to understanding vulnerability factors, as well as potential new treatment strategies in several common neuropsychiatric disorders. The handbook comprises four major sections: (1) Introduction to sex differences in neuroanatomy and neurophysiology, (2) Description of the impact of genetic, epigenetic, sex hormonal and other environmental effects on cerebral sex dimorphism, (3) Review of sex differences in neurologic disorders, and (4) Review of sex differences in psychiatric disorders. Explores sex differences in human neuroanatomy and neurophysiology Offers a pathway toward a gender-specific treatment of neurologic and psychiatric disorders Provides an overview of the genetics of sex hormones, human brain structure, and function, as well as the epigenetics, environment and social context

Sex Differences in the Central Nervous System

Sex Differences in the Central Nervous System
  • Author : Rebecca M. Shansky
  • Publisher :Unknown
  • Release Date :2015-09-14
  • Total pages :428
  • ISBN : 9780128021989
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Summary : Sex Differences in the Central Nervous System offers a comprehensive examination of the current state of sex differences research, from both the basic science and clinical research perspectives. Given the current NIH directive that funded preclinical research must consider both females and males, this topic is of interest to an increasing percentage of the neuroscience research population. The volume serves as an invaluable resource, offering coverage of a wide range of topics: sex differences in cognition, learning, and memory, sex hormone signaling mechanisms, neuroimmune interactions, epigenetics, social behavior, neurologic disease, psychological disorders, and stress. Discussions of research in both animal models and human patient populations are included. Details how sex hormones have widespread effects on the nervous system and influence the way males and females function Assists readers in determining how sex impacts their research and practice, and assists in determining how to adjust research programs to incorporate sex influences Includes discussions of research in both animal models and human patient populations, and at various developmental stages Features revised and updated chapters by leaders in the field around the globe—the broadest, most expert coverage available

How Sex and Gender Impact Clinical Practice

How Sex and Gender Impact Clinical Practice
  • Author : Marjorie R. Jenkins,Connie B. Newman
  • Publisher :Unknown
  • Release Date :2020-12-02
  • Total pages :360
  • ISBN : 9780128167502
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Summary : How Sex and Gender Impact Clinical Practice: An Evidence-Based Guide to Patient Care enables primary care clinicians by providing a framework to understand differences and better care for patients in their practice. Each chapter covers a subspecialty in medicine and discusses the influence of sex hormones on disease, along with sex and gender-based differences in clinical presentation, physical examination, laboratory results, treatment regimens, comorbidities and prognosis. Illustrative case examples and practical practice points help each chapter come alive. A special chapter on communication differences between men and women assists clinicians in their conversations with patients. This book fills an important need by applying years of research findings to sex and gender specific medical care and demonstrating that an individualized approach to patient care will lead to improved detection, treatment and prevention of disease. Explores the effects of sex and gender on disease presentation, treatment and prognosis, and how these differences influence clinical decision-making Provides practical guidance that helps clinicians implement a more individualized approach to patient care Contains information on diseases in each major specialty, as well as chapters on communication, pharmacology and public health challenges

Alzheimer's Disease

Alzheimer's Disease
  • Author : Inga Zerr
  • Publisher :Unknown
  • Release Date :2015-07-01
  • Total pages :372
  • ISBN : 9789535121374
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Summary : There is a wide scope of clinical phenomenology in Alzheimers disease, regarding the age of onset, presenting features, rate of progression and appearance of other clinical manifestation. Although clinical appearance and neuropathological hallmarks have been defining AD since its first description, major factors which trigger pathology are still unknown. The role of comorbidity is discussed controversially. Important environmental risk factors in AD development are continuous stress, low education and cardiovascular risk factors such as alcohol intake, smoking, hypertension. The role of lipids and cholesterol has been recognized, but the relevant pathogenetic steps are still to be identified. There is an urgent need to understand molecular disease pathogenesis in order to develop early therapeutic targets for the disease.

Sex Differences in Physiology

Sex Differences in Physiology
  • Author : Gretchen Neigh,Megan Mitzelfelt
  • Publisher :Unknown
  • Release Date :2016-05-10
  • Total pages :236
  • ISBN : 9780128026083
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Summary : Sex Differences in Physiology is an all-encompassing reference that details basic science research into sex differences in all physiological fields. It includes scientific discoveries concerning sex differences in cardiovascular, respiratory, renal, gastrointestinal, and musculoskeletal physiology. In addition, coverage of the development, endocrinology, neurophysiology, immunity, and metabolism is included, making this important reference a resource that will meet the needs of investigators interested in incorporating sex differences into their research programs, while also providing clinicians with the basis for providing the best sex-based medical treatment options available. Provides a sweeping, organ-by-organ review of currently observed sex differences in animal models and human disease Explains how sex differences influence physiology and disease Provides the critical knowledge on sex differences for better understanding of prevention and treatment of diseases

Update on Dementia

Update on Dementia
  • Author : Davide Moretti
  • Publisher :Unknown
  • Release Date :2016-09-28
  • Total pages :558
  • ISBN : 9789535126546
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Summary : The dementia challenge is the largest health effort of the times we live in. The whole society has to move to a realization of the significance of prioritization to make an attempt in the direction of mental health promotion and dementia risk reduction. New priorities for research are needed to go far beyond the usual goal of constructing a disease course-modifying medication. Moreover, a full empowerment and engagement of men and women living with dementia and their caregivers, overcoming stigma and discrimination should be promoted. The common efforts and the final aim will have to be the progress of a ''dementia-constructive'' world, where people with dementia can take advantage of equal opportunities.

The Cambridge Handbook of the International Psychology of Women

The Cambridge Handbook of the International Psychology of Women
  • Author : Fanny M. Cheung,Diane F. Halpern
  • Publisher :Unknown
  • Release Date :2020-06-30
  • Total pages :592
  • ISBN : 1108473032
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Summary : There is a growing knowledge base in understanding the differences and similarities between women and men, as well as the diversities among women and sexualities. Although genetic and biological characteristics define human beings conventionally as women and men, their experiences are contextualized in multiple dimensions in terms of gender, sexuality, class, age, ethnicity, and other social dimensions. Beyond the biological and genetic basis of gender differences, gender intersects with culture and other social locations which affect the socialization and development of women across their life span. This handbook provides a comprehensive and up-to-date resource to understand the intersectionality of gender differences, to dispel myths, and to examine gender-relevant as well as culturally relevant implications and appropriate interventions. Featuring a truly international mix of contributors, and incorporating cross-cultural research and comparative perspectives, this handbook will inform mainstream psychology of the international literature on the psychology of women and gender.

A Demographic Perspective on Gender, Family and Health in Europe

A Demographic Perspective on Gender, Family and Health in Europe
  • Author : Gabriele Doblhammer,Jordi Gumà
  • Publisher :Unknown
  • Release Date :2018-02-12
  • Total pages :303
  • ISBN : 9783319723563
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Summary : This open access book examines the triangle between family, gender, and health in Europe from a demographic perspective. It helps to understand patterns and trends in each of the three components separately, as well as their interdependencies. It overcomes the widely observable specialization in demographic research, which usually involves researchers studying either family or fertility processes or focusing on health and mortality. Coverage looks at new family and partnership forms among the young and middle-aged, their relationship with health, and the pathways through which they act. Among the old, lifelong family biography and present family situation are explored. Evidence is provided that partners advancing in age start to resemble each other more closely in terms of health, with the health of the partner being a crucial factor of an individual’s own health. Gender-specific health outcomes and pathways are central in the designs of the studies and the discussion of the results. The book compares twelve European countries reflecting different welfare state regimes and offers country-specific studies conducted in Austria, Germany, Italy - all populations which have received less attention in the past - and Sweden. As a result, readers discover the role of different concepts of family and health as well as comparisons within European countries and ethnic groups. It will be an insightful resource for students, academics, policy makers, and researchers that will help define future research in terms of gender and public health.

The Spectrum of Hope

The Spectrum of Hope
  • Author : Gayatri Devi
  • Publisher :Unknown
  • Release Date :2017-10-31
  • Total pages :256
  • ISBN : 9781523500581
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Summary : Imagine finding a glimmer of good news in a diagnosis of Alzheimer’s. And imagine how that would change the outlook of the 5 million Americans who suffer from Alzheimer’s disease and other dementias, not to mention their families, loved ones, and caretakers. A neurologist who’s been specializing in dementia and memory loss for more than 20 years, Dr. Gayatri Devi rewrites the story of Alzheimer’s by defining it as a spectrum disorder—like autism, Alzheimer’s is a disease that affects different people differently. She encourages people who are worried about memory impairment to seek a diagnosis, because early treatment will enable doctors and caregivers to manage the disease more effectively through drugs and other therapies. Told through the stories of Dr. Devi’s patients, The Spectrum of Hope is the kind of narrative medical writing that grips the reader, humanizes the science, and offers equal parts practical advice and wisdom with skillful ease. But beyond the pleasures of great reading, it’s a book that offers real hope. Here are chapters on how to maintain independence and dignity; how to fight depression, anxiety, and apathy; how to communicate effectively with a person suffering from dementia. Plus chapters on sexuality, genetics, going public with the diagnosis, even putting together a bucket list—because through her practice, Dr. Devi knows that the majority of Alzheimer’s patients continue to live and work in their communities. They babysit their grandkids, drive to the store (or own the store), serve their clients, or otherwise live fulfilling lives. That’s news that 5 million people are waiting to hear.

The Neurobiology of Alzheimer's Disease

The Neurobiology of Alzheimer's Disease
  • Author : Suzanne Corkin,Roger M. Nitsch,John Herbert Growdon
  • Publisher :Unknown
  • Release Date :1996
  • Total pages :439
  • ISBN : 0897669738
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Summary : The overall goal of the International Study Group on the Pharmacology of Memory Disorders Associated with Ageing is to point out discoveries that shed light on the potential causes of Alzheimer's disease, its pathogenesis, and the biological mechanisms that could underlie its cure. This eighth meeting in the series, aims to stimulate research in dementia and increase the transfer of information from the basic sciences to physicians and the pharmaceutical industry."

Sex and Gender Aspects in Clinical Medicine

Sex and Gender Aspects in Clinical Medicine
  • Author : Sabine Oertelt-Prigione,Vera Regitz-Zagrosek
  • Publisher :Unknown
  • Release Date :2011-11-15
  • Total pages :204
  • ISBN : 0857298321
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Summary : This book is a concise, easy to read professional text with a focus on practical aspects. All chapters include tables on sex/gender differences in symptoms and management and a series of suggestions to the novice in the field. Chapters are specialty-specific. The focus is not on women’s health, but the presentation of differences in clinical symptoms, management and outcomes in women and men. Gender Medicine strives to employ the knowledge about these differences to improve diagnosis, better understand pathogenesis and advance patient-oriented therapy.

Sex and Gender Differences in Pharmacology

Sex and Gender Differences in Pharmacology
  • Author : Vera Regitz-Zagrosek
  • Publisher :Unknown
  • Release Date :2012-10-02
  • Total pages :602
  • ISBN : 9783642307263
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Summary : This is the very first book to deal with sex and gender differences in drug therapy - an increasingly recognized medical need. It starts with an overview on S/G in clinical syndromes and a documentation of the medical and socioeconomic damage caused by gender specific adverse drug effects. Part I covers S/G differences in pharmacokinetics. Researchers will be satisfied by the detailed discussion of the mechanisms of S/G differences in drug effects that represents cutting edge science and includes interaction of drugs with sex hormones, genomic and epigenetic mechanisms. It also covers S/G in drug development, in animal models and clinical development and S/G in drug prescriptions. Part II targets S/G differences in drug effects in cardiovascular, pulmonary, CNS, neuromuscular, neuropsychiatric and metabolic diseases, in cancer, inflammation, and rheumatic diseases, in bacterial and retroviral infections, thrombosis, embolism. New drugs will be discussed.

Neurology of Sexual and Bladder Disorders

Neurology of Sexual and Bladder Disorders
  • Author : David B. Vodusek,Francois Boller
  • Publisher :Unknown
  • Release Date :2015-05-21
  • Total pages :516
  • ISBN : 9780444632548
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Summary : The neurology of sex and bladder disorders requires specialized knowledge and represents a challenge for clinical neurologists focused on the neurological condition. Sex and bladder disorders are often related to more general neurological disorders like Parkinson’s disease and multiple sclerosis, and often the sex and bladder disorders are passed to specialists in urology. Neurology of Sexual and Bladder Disorders: Handbook of Clinical Neurology is a focused, yet comprehensive overview that provides complete tutorial reference to the science, diagnosis and treatment of sex and bladder disorders from a neurologic perspective. Comprehensive coverage of the neurology of sex and bladder disorders Details the latest techniques for the study, diagnosis and treatment of sex and bladder dysfunction from a neurological perspective A focused reference for clinical practitioners and neurology research communities

Physical Activity and the Aging Brain

Physical Activity and the Aging Brain
  • Author : Ronald Ross Watson
  • Publisher :Unknown
  • Release Date :2016-12-15
  • Total pages :238
  • ISBN : 9780128052624
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Summary : Physical Activity and the Aging Brain: Effects of Exercise on Neurological Function is a complete guide to the manifold effects of exercise and physical activity on the aging brain. Cognitive decline and motor impairment, onset of diseases and disorders, and even changes in family structure and social settings that occur as we age can all impact activity levels, yet continued physical activity is crucial for successful neurological functioning. This book examines the role that exercise and physical activity play in halting or modulating the deleterious effects of these numerous aging concerns by first examining the current state of research into how exercise manifests physical changes in the brain. It then discuss how physical activity combines with other lifestyle factors to benefit the aging brain, including nutrition, computerized brain training, and social engagement. Most significantly, it also covers how physical activity can serve as therapy to help alleviate the symptoms of various neurological diseases impacting aging populations, with particular emphasis on Alzheimer’s disease and age-related cognitive decline. The book provides broad coverage of the effects of exercise and physical activity on the aging brain, its therapeutic effects, and the many factors that influence the aging process. Presents research scientists with a complete understanding of the role of exercise in healthy brain aging Considers the roles of nutrition, the mind-body connection, and other lifestyle factors Presents a major resource for exercise and physical activity in the neurological health of older adults Provides a synopsis of key ideas associated with the many aspects of physical activity, along with lifestyle factors that can modify neurological diseases and age-related neurological decline

Encyclopedia of Geropsychology

Encyclopedia of Geropsychology
  • Author : Nancy A. Pachana
  • Publisher :Unknown
  • Release Date :2016-10-10
  • Total pages :1500
  • ISBN : 9812870814
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Summary : This encyclopedia brings together key established and emerging research findings in geropsychology. It is a comprehensive coverage of the entire breadth of the field, giving readers access to all major subareas and illustrating their interconnections with other disciplines. Entries delve deep into key areas of geropsychology such as perception, cognition, clinical, organizational, health, social, experimental and neuropsychology. In addition to that, the encyclopedia covers related disciplines such as neuroscience, social science, population health, public policy issues pertaining to retirement, epidemiology and demography and medicine. Paying careful attention to research internationally, it cites English and non-English empirical literature from around the globe. This encyclopedia is relevant to a wide audience that include researchers, clinicians, students, policy makers and nongovernmental agencies.

Health, United States, 2016, with Chartbook on Long-Term Trends in Health

Health, United States, 2016, with Chartbook on Long-Term Trends in Health
  • Author : National Center for Health Statistics
  • Publisher :Unknown
  • Release Date :2017-08-16
  • Total pages :570
  • ISBN : 0160939771
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Summary : This annual overview report of national trends in health statistics contains a Chartbook that assesses the nation's health by presenting trends and current information on selected measures of morbidity, mortality, health care utilization and access, health risk factors, prevention, health insurance, and personal health-care expenditures. Chapters devoted to population characteristics, prevention, health risk factors, health care resources, personal health care expenditures, health insurance, and trend tables may provide the health/medical statistician, data analyst, biostatistician with additional information to complete experimental studies or provide necessary research for pharmaceutical companies to gain data for modeling and sampling. Undergraduate students engaged in applied mathematics or statistical compilations to graduate students completing biostatistics degree programs to include statistical inference principles, probability, sampling methods and data analysis as well as specialized medical statistics courses relating to epidemiology and other health topics may be interested in this volume. Related products: Your Guide to Choosing a Nursing Home or Other Long-Term Services & Supports available here: https://bookstore.gpo.gov/products/your-guide-choosing-nursing-home-or-other-long-term-services-supports Health Insurance Coverage in the United States, 2014 available here: https://bookstore.gpo.gov/products/health-insurance-coverage-united-states-2014 "Some System of the Nature Here Proposed": Joseph Lovell's Remarks on the Sick Report, Northern Department, U.S. Army, 1817, and the Rise of the Modern US Army Medical Department can be found here: https://bookstore.gpo.gov/products/some-system-nature-here-proposed-joseph-lovells-remarks-sick-report-northern-department-us Guide to Clinical Preventive Services 2014: Recommendations of the U.S. Preventive Services Task Force (ePub) -Free digital eBook download available at the US Government Online Bookstore here: https://bookstore.gpo.gov/products/guide-clinical-preventive-services-2014-recommendations-us-preventive-services-task-force --Also available for FREE digital eBook download from Apple iBookstore, BarnesandNoble.com (Nook Bookstore), Google Play eBookstore, and Overdrive -Please use ISBN: 9780160926426 to search these commercial platforms.

Women's Health Research

Women's Health Research
  • Author : Institute of Medicine,Board on Population Health and Public Health Practice,Committee on Women's Health Research
  • Publisher :Unknown
  • Release Date :2010-10-27
  • Total pages :438
  • ISBN : 0309163374
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Summary : Even though slightly over half of the U.S. population is female, medical research historically has neglected the health needs of women. However, over the past two decades, there have been major changes in government support of women's health research--in policies, regulations, and the organization of research efforts. To assess the impact of these changes, Congress directed the Department of Health and Human Services (HHS) to ask the IOM to examine what has been learned from that research and how well it has been put into practice as well as communicated to both providers and women. Women's Health Research finds that women's health research has contributed to significant progress over the past 20 years in lessening the burden of disease and reducing deaths from some conditions, while other conditions have seen only moderate change or even little or no change. Gaps remain, both in research areas and in the application of results to benefit women in general and across multiple population groups. Given the many and significant roles women play in our society, maintaining support for women's health research and enhancing its impact are not only in the interest of women, they are in the interest of us all.

Sex Hormones and Gender Differences in Immune Responses

Sex Hormones and Gender Differences in Immune Responses
  • Author : Elena Ortona,Marina Pierdominici,Virginia Rider
  • Publisher :Unknown
  • Release Date :2019-07-31
  • Total pages :229
  • ISBN : 9782889459360
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Summary : Increasingly clear evidence points to the need to consider gender differences in human health. In this collection of papers, recent research that supports gender differences in the immune system are discussed. We have loosely divided the eBook into two sections. The first section focuses on the role of steroid hormone interactions within the immune system, and their impact on autoimmune diseases, infection and allergy. This section contains comprehensive reviews and an opinion article about this topic. In the following section, original research articles revolve around the effects of the sex hormones on immune response. Two original manuscripts deal with the role of estrogen receptors in autoimmune diseases. Other two research articles discuss the role of the immune system during pregnancy. Finally, differences between males and females in infections are the topic of further two research articles. We are confident this collection of papers will be important for exploring and developing a greater understanding of gender differences in human health and disease.