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Studies on Hepatitis Viruses

Studies on Hepatitis Viruses
  • Author : Satya Prakash Gupta
  • Publisher :Unknown
  • Release Date :2018-06-20
  • Total pages :242
  • ISBN : 9780128133316
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Summary : Studies on Hepatitis Viruses: Life Cycle, Structure, Functions, and Inhibition presents the latest on this systemic infection that predominantly affects the liver with inflammation that can be acute or chronic. Hepatitis viruses have been the subject of intense study in the last twenty years, with a wealth of information related to their lifecycle, structure, functions and inhibition being presented. This book compiles the most important developments and research, giving users a very useful guide on this evolving area of virology and medicinal chemistry. Provides comprehensive, state-of-the-art coverage of hepatitis virus infections, the virus' lifecycle, and mechanisms of protease inhibition Analyzes structure-activity relationships of inhibitors of viral hepatitis Presents an in-depth view of the structure and function of viral hepatitis Discusses classification, epidemiology, pathogenesis, natural history, clinical manifestations, diagnosis, complications, associated disorders and animal models

Studies on Hepatitis Viruses

Studies on Hepatitis Viruses
  • Author : Satya Prakash Gupta
  • Publisher :Unknown
  • Release Date :2018-07-06
  • Total pages :242
  • ISBN : 0128133309
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Summary : Studies on Hepatitis Viruses: Life Cycle, Structure, Functions, and Inhibition presents the latest on this systemic infection that predominantly affects the liver with inflammation that can be acute or chronic. Hepatitis viruses have been the subject of intense study in the last twenty years, with a wealth of information related to their lifecycle, structure, functions and inhibition being presented. This book compiles the most important developments and research, giving users a very useful guide on this evolving area of virology and medicinal chemistry. Provides comprehensive, state-of-the-art coverage of hepatitis virus infections, the virus' lifecycle, and mechanisms of protease inhibition Analyzes structure-activity relationships of inhibitors of viral hepatitis Presents an in-depth view of the structure and function of viral hepatitis Discusses classification, epidemiology, pathogenesis, natural history, clinical manifestations, diagnosis, complications, associated disorders and animal models

Practical Management of Chronic Viral Hepatitis

Practical Management of Chronic Viral Hepatitis
  • Author : Gaetano Serviddio
  • Publisher :Unknown
  • Release Date :2013-05-29
  • Total pages :382
  • ISBN : 9789535111092
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Summary : Continuous acquisition of new knowledge in Medicine is essential to ensure progression in diagnostics and therapeutics. In the last decade the discipline of Hepatology has achieved critical progress in the treatment of viral hepatitis. The present book has been realized by a team of experts daily facing clinical problems in the prevention and management of liver diseases and has been designed for a global readership to offer some practical tips to physicians who want update their level of practice in the field. Its a practical volume for daily reference but also an instrument for improving expertise in viral hepatology and discovering the unresolved issues. Management of HBV and HCV hepatitis in young and elderly, HEV hepatitis, evaluation of liver fibrosis, hepatocellular carcinoma, vaccine and prevention and patient education are some of the most important topics covered by the authors. In addition, an outstanding chapter on the skin involvement during viral hepatitis and the tools to manage them during triple therapy is included in the book.

Viral Hepatitis

Viral Hepatitis
  • Author : Howard C. Thomas,Anna S. F. Lok,Stephen A. Locarnini,Arie J. Zuckerman
  • Publisher :Unknown
  • Release Date :2013-07-22
  • Total pages :624
  • ISBN : 9781118637333
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Summary : The 4th edition of Viral Hepatitis coverscomprehensively the entire complex field of infections caused byall of the different hepatitis viruses, which affect many millionsof people throughout the world with considerable morbidity andmortality. Howard Thomas and Arie Zuckerman are joined by Anna Lok from theUSA and Stephen Locarnini from Australia as Editors. Theyhave recruited leading researchers and physicians from manycountries, who have produced an authoritative account of currentknowledge and research on this important infection, including newinsights into immune response to HBV and HCV. The result is a comprehensive account on all aspects of viralhepatitis, including rapid advances in the diagnosis, management,treatment and prevention of a complex infection, which in the caseof hepatitis B, C and D may lead to severe complications includingchronic hepatitis, cirrhosis and hepatocellular carcinoma. The latest edition of Viral Hepatitis offers an essentialresource of current information for hepatologists,gastroenterologists, infectious diseases specialists and otherclinicians, researchers, public health physicians and National andInternational Health Authorities.

Hepatitis and Liver Cancer

Hepatitis and Liver Cancer
  • Author : Institute of Medicine,Board on Population Health and Public Health Practice,Committee on the Prevention and Control of Viral Hepatitis Infections
  • Publisher :Unknown
  • Release Date :2010-05-23
  • Total pages :252
  • ISBN : 9780309146289
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Summary : The global epidemic of hepatitis B and C is a serious public health problem. Hepatitis B and C are the major causes of chronic liver disease and liver cancer in the world. In the next 10 years, 150,000 people in the United States will die from liver disease or liver cancer associated with chronic hepatitis B virus (HBV) or hepatitis C virus (HCV) infections. Today, between 800,000 and 1.4 million people in the United States have chronic hepatitis B and between 2.7 and 3.9 million have chronic hepatitis C. People most at risk for hepatitis B and C often are the least likely to have access to medical services. Reducing the rates of illness and death associated with these diseases will require greater awareness and knowledge among health care workers, improved identification of at-risk people, and improved access to medical care. Hepatitis B is a vaccine-preventable disease. Although federal public health officials recommend that all newborns, children, and at-risk adults receive the vaccine, about 46,000 new acute cases of the HBV infection emerge each year, including 1,000 in infants who acquire the infection during birth from their HBV-positive mothers. Unfortunately, there is no vaccine for hepatitis C, which is transmitted by direct exposure to infectious blood. Hepatitis and Liver Cancer identifies missed opportunities related to the prevention and control of HBV and HCV infections. The book presents ways to reduce the numbers of new HBV and HCV infections and the morbidity and mortality related to chronic viral hepatitis. It identifies priorities for research, policy, and action geared toward federal, state, and local public health officials, stakeholder, and advocacy groups and professional organizations.

Viral Hepatitis

Viral Hepatitis
  • Author : Arie J. Zuckerman,Howard C. Thomas
  • Publisher :Unknown
  • Release Date :1993
  • Total pages :590
  • ISBN : UOM:39015032474838
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Summary : Discusses all aspects of viral hepatitis, from structure and molecular virology, and natural history and experimental models, to epidemiology, diagnosis and prevention. A section on clinical aspects covers transfusion-associated hepatitis, occupational aspects and paediatric infection.

A National Strategy for the Elimination of Hepatitis B and C

A National Strategy for the Elimination of Hepatitis B and C
  • Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Committee on a National Strategy for the Elimination of Hepatitis B and C
  • Publisher :Unknown
  • Release Date :2017-06-30
  • Total pages :296
  • ISBN : 9780309457323
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Summary : Hepatitis B and C cause most cases of hepatitis in the United States and the world. The two diseases account for about a million deaths a year and 78 percent of world's hepatocellular carcinoma and more than half of all fatal cirrhosis. In 2013 viral hepatitis, of which hepatitis B virus (HBV) and hepatitis C virus (HCV) are the most common types, surpassed HIV and AIDS to become the seventh leading cause of death worldwide. The world now has the tools to prevent hepatitis B and cure hepatitis C. Perfect vaccination could eradicate HBV, but it would take two generations at least. In the meantime, there is no cure for the millions of people already infected. Conversely, there is no vaccine for HCV, but new direct-acting antivirals can cure 95 percent of chronic infections, though these drugs are unlikely to reach all chronically-infected people anytime soon. This report, the second of two, builds off the conclusions of the first report and outlines a strategy for hepatitis reduction over time and specific actions to achieve them.

Hepatitis C

Hepatitis C
  • Author : Imran Shahid
  • Publisher :Unknown
  • Release Date :2018-10-10
  • Total pages :212
  • ISBN : 9781789842074
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Summary : The propagation of hepatitis C from acute to chronic infection and afterward to end-stage liver diseases (hepatic fibrosis, cirrhosis, and hepatocellular carcinoma) involves a highly orchestrated series of molecular and cellular events, including a plethora of genes and cell signaling cascades. The treatment paradigms was revolutionized after the development and approval of all oral interferon-free direct-acting antivirals achieving higher sustained virologic response rates in treated individuals. This book pragmatically overviews the intricate interplay between viral and host factors during hepatitis C virus infection progression, as well as other hepatitis C-associated clinical implications. Hepatitis C - From Infection to Cure also provides up-to-date information about hepatitis C cures for clinicians, physicians, and healthcare providers with an ample understanding of the current treatment horizon, as well as other investigational and emerging treatment strategies. The authors with their valuable scientific contributions belong to many eminent institutes around the world and are much experienced in hepatitis C virology, pathology, and therapeutics.

Bioinformatics

Bioinformatics
  • Author : Ibrokhim Y. Abdurakhmonov
  • Publisher :Unknown
  • Release Date :2016-07-27
  • Total pages :268
  • ISBN : 9789535125464
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Summary : An interdisciplinary bioinformatics science aims to develop methodology and analysis tools to explore large-volume of biological data using conventional and modern computer science, statistics, and mathematics, as well as pattern recognition, reconstruction, machine learning, simulation and iterative approaches, molecular modeling, folding, networking, and artificial intelligence. Written by international team of life scientists, this Bioinformatics book provides some updates on bioinformatics methods, resources, approaches, and genome analysis tools useful for molecular sciences, medicine and drug designs, as well as plant sciences and agriculture. I trust chapters of this book should provide advanced knowledge for university students, life science researchers, and interested readers on some latest developments in the bioinformatics field.

Hepatitis C Virus Disease

Hepatitis C Virus Disease
  • Author : Emilio Jirillo
  • Publisher :Unknown
  • Release Date :2007-11-20
  • Total pages :308
  • ISBN : 9780387713762
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Summary : Despite numerous hepatitis C virus infection studies, its pathogenesis and medical treatment have not been fully explained. This comprehensive volume, written by experts in the field, covers the most recent advances in the study of HCV, moving from basic research to clinical applications. The first chapters of this volume analyze the full spectrum of immune responses to HCV. The volume also includes contributions that explain the state of the art in IFN-alpha treatment of HCV patients.

Guidelines on Hepatitis B and C Testing

Guidelines on Hepatitis B and C Testing
  • Author : World Health Organization
  • Publisher :Unknown
  • Release Date :2018-02-06
  • Total pages :202
  • ISBN : 924154998X
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Summary : Testing and diagnosis of hepatitis B (HBV) and C (HCV) infection is the gateway for access to both prevention and treatment services, and is a crucial component of an effective response to the hepatitis epidemic. Early identification of persons with chronic HBV or HCV infection enables them to receive the necessary care and treatment to prevent or delay progression of liver disease. Testing also provides an opportunity to link people to interventions to reduce transmission, through counselling on risk behaviors and provision of prevention commodities (such as sterile needles and syringes) and hepatitis B vaccination. These are the first WHO guidelines on testing for chronic HBV and HCV infection and complement published guidance by WHO on the prevention, care and treatment of chronic hepatitis C and hepatitis B infection. These guidelines outline the public health approach to strengthening and expanding current testing practices for HBV and HCV, and are intended for use across age groups and populations.

Update on Hepatitis C

Update on Hepatitis C
  • Author : Martina Smolic,Aleksandar Vcev,George Wu
  • Publisher :Unknown
  • Release Date :2017-10-04
  • Total pages :238
  • ISBN : 9789535135630
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Summary : In the past few years, remarkable progress has been made in our understanding of HCV biology, pathogenesis of infection, and structure-function relationships. This has led to quantum advances in clinical efficacy and tolerability. Yet, in spite of this amazing progress, there remain obstacles to widespread successful treatment. These issues include biological failures even with direct-acting agents, lack of options for individual with organ failures, drug-drug interactions, access to medications either due to lack of availability or affordability, and psychiatric and social issues. These problems are likely to remain in the future. Therefore, this book has been created by distinguished faculties from around the world to address the progress in our understanding of HCV infection and to review new treatment options, limitations, and accessibility of new therapeutic options.

Hepatitis B and C

Hepatitis B and C
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2020-04-08
  • Total pages :112
  • ISBN : 9781789239478
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Summary : This book on Hepatitis B and C contains very useful and recent information about the general characteristics of these common types of chronic liver infections. Referred to as Hepatitis B, there are three chapters describing the main epidemiological, clinical, therapeutic, and prognosis aspects. The molecular variants for HBsAg, its genotyping, and their clinical implications are fully analyzed. The implications of coinfection Hepatitis B and C in HIV patients and their treatment are described. In relation to Hepatitis C, there are three chapters describing the general characteristics of this chronic viral infection. The challenges and strategies for access to treatment of Hepatitis C in Latin America are fully covered and these can be applied in other countries with similar epidemiological and financial problems for access to treatment on a large scale. The role of direct-acting antivirals (DAA) in the treatment of chronic Hepatitis C infection with liver cirrhosis is clearly documented.

Advances in Treatment of Hepatitis C and B

Advances in Treatment of Hepatitis C and B
  • Author : Naglaa Allam
  • Publisher :Unknown
  • Release Date :2017-03-08
  • Total pages :406
  • ISBN : 9789535129936
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Summary : As in many areas of medicine, treatment of viral hepatitis has seen an acceleration of change driven by new therapies and evolving technology. Thanks to the direct-acting antiviral agents (DAAs), the era of HCV eradication and cure has begun. As regards to hepatitis B therapy, potent antiviral drugs for suppression of viral replication are available, new research activities to enhance eradication are visible, and these may influence clinical practice in the coming years. This book covers the latest advances in hepatitis C and hepatitis B therapeutics as well as the emerging and investigational treatment strategies. "Advances in Treatment of Hepatitis C and Hepatitis B" book is an up-to-date source of information for physicians, residents, and advanced medical students seeking a broader understanding of treatment of viral hepatitis. The authors of the chapters come from many eminent centers around the world and are experts in their respective fields.

Hepatitis B Virus and Liver Disease

Hepatitis B Virus and Liver Disease
  • Author : Jia-Horng Kao,Ding-Shinn Chen
  • Publisher :Unknown
  • Release Date :2018-01-12
  • Total pages :360
  • ISBN : 9789811048432
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Summary : This book provides a comprehensive, state-of-the art review of HBV infection and liver disease. It discusses new data on basic and translational medicine, including the viral life cycle, the immunopathogenesis of virus-induced chronic hepatitis, viral and host genetic factors affecting disease progression, and the mechanism of virus-induced hepatocarcinogenesis, as well as their potential applications in daily clinical practice. The clinical aspects of chronic HBV infection are examined in chapters on the global epidemiology, efficacy of HBV vaccination, natural history, co-infections with HCV, HDV or HIV, and management of special populations including children, pregnant women and patients undergoing immunosuppressive therapy. Further, it describes the advances and perspectives in the development of novel antiviral treatments as possible cures for HBV infection. The book is a valuable resource for medical students, physicians, and researchers who are interested in managem ent of patients with chronic HBV infection and investigation of HBV infection.

Diagnosis and Management of Autoimmune Hepatitis

Diagnosis and Management of Autoimmune Hepatitis
  • Author : Mark W. Russo
  • Publisher :Unknown
  • Release Date :2020-03-17
  • Total pages :166
  • ISBN : 9783030336288
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Summary : This text provides a concise yet comprehensive overview of autoimmune hepatitis (AIH). The book reviews diagnosis criteria for AIH, biochemical and histologic findings in typical and atypical cases, and treatment with first, second, and third line therapies. Furthermore, the book discusses management of AIH for specific patient populations, including pediatric patients, pregnant patients, and patients undergoing liver transplantation. Criteria for stopping therapy and risk of relapse, studies demonstrating the efficacy and safety of alternatives to corticosteroids, and diagnosis and treatment of overlap syndromes are also explored in the text. Written by experts in the field, Diagnosis and Treatment of Autoimmune Hepatitis: A Clinical Guide is a state-of-the-art resource for clinicians and practitioners who treat and manage patients with AIH

Hepatitis B

Hepatitis B
  • Author : Baruch S. Blumberg
  • Publisher :Unknown
  • Release Date :2003-11-16
  • Total pages :244
  • ISBN : 9780691116235
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Summary : The Hepatitis B virus comes under the microscope as a renowned doctor discusses this killer virus and the vaccine that is reducing its mortality around the globe.

Viral Hepatitis: Acute Hepatitis

Viral Hepatitis: Acute Hepatitis
  • Author : Resat Ozaras,Joop E. Arends
  • Publisher :Unknown
  • Release Date :2019-02-01
  • Total pages :107
  • ISBN : 9783030035358
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Summary : This book presents up-to-date, practically oriented information on major topics in acute hepatitis. The coverage encompasses epidemiology; diagnosis, including molecular methods; treatment and challenges; and the management of co-infections. The book opens by examining the local and global epidemiology of acute hepatitis. Detailed attention is then paid to each of acute hepatitis A, acute hepatitis B, acute hepatitis C, hepatitis D co-infection, and hepatitis E. Acute Hepatitis will be of high value for general practitioners and specialists in gastroenterology, infectious diseases, and internal medicine. It will be international in scope in terms of both authorship and appeal.

Hepatitis B and D Protocols

Hepatitis B and D Protocols
  • Author : Robert Kiyoshi Hamatake,Johnson Yiu-Nam Lau
  • Publisher :Unknown
  • Release Date :2004
  • Total pages :376
  • ISBN : 9781592596690
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Summary : These volumes offer both new and experienced investigators an encyclopedic collection of powerful tools for studying HBV and HDV infections, as well as an essential resource for finding new therapies to treat chronically infected patients. In the first volume, the authors focus on readily reproducible molecular methods for the identificationa and qualification of viral markers, the detection and impact of viral variants, and the study of the viral life cycle. In the second volulme, the authors focus on protocols for the study of host immune responses to infection, in vitro and in vivo models of infections, and the development of antivirals.

Imported Infectious Diseases

Imported Infectious Diseases
  • Author : Fernando Cobo
  • Publisher :Unknown
  • Release Date :2014-10-07
  • Total pages :240
  • ISBN : 9781908818737
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Summary : The increase of immigrant population in developed countries (mainly in Europe and North America) together with an important increase of international travel worldwide are the two most important causes that have contributed to the introduction and diagnosis of imported/tropical infectious diseases in these countries. These factors have had an important impact in developed countries in both social and economic aspects. Imported Infectious Diseases focuses not only on describing the infections, but also in evaluating the current epidemiology, the economic and social impact and the possibility to apply immunization measures and vaccines. The main purpose of this book is to give an overview of the current most important and frequent imported infectious diseases in developed countries. The first chapter informs about the medical services that are being offered to the immigrants in the main developed countries depending on the legal situation. Following chapters describe the main surveillance systems for these kinds of diseases, mainly in Europe and North America. Finally, remaining chapters contain sections on epidemiology, pathogenesis, clinical features, diagnosis, treatment and prevention.

Hepatitis B Virus

Hepatitis B Virus
  • Author : Haitao Guo,Andrea Cuconati
  • Publisher :Unknown
  • Release Date :2016-12-15
  • Total pages :297
  • ISBN : 1493966987
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Summary : This volume serves as a reference for the dissemination of advances made in the study of Hepatitis B Virus (HBV). Hepatitis B Virus: Methods and Protocols details protocols and techniques ranging from cell culture studies to in vivo and clinical immunology. The chapters in this book discuss treatments of in vitro infection systems, analysis and quantification of cccDNA and its mutations; in vitro polymerase activity assays; cellular trafficking of core proteins; intracellular calcium metabolism; detection, cloning, and sequencing of HBV markers; and new strategies aimed at exploiting new mechanisms for drug discovery. The book also covers classical methods for resolution of extracellular viral particles by native gel electrophoresis, and methods for detecting HBV antigens in drug discovery. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Hepatitis B Virus: Methods and Protocols is a valuable tool for researchers to use toward their advanced studies in HBV.