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Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
  • Author : Robert G. Lahita
  • Publisher :Unknown
  • Release Date :2004-06-09
  • Total pages :1343
  • ISBN : 0080474543
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Summary : Systemic Lupus Erythematosus, Fourth Edition, provides an understanding of the basic mechanisms as well as the diagnostic and therapeutic aspects of lupus. This book is attractive to both the investigative community and clinicians. As lupus has become a paradigm for the study of autoimmune disease, immunologists investigating autoimmunity are becoming more interested in lupus. Basic immunology of phospholipid antibodies, clotting abnormailities, issues concerning pathogenetic fit with SLE, and newest methods of therapy of APLS are given in this newest edition of a classic reference. * Comprehensive current coverage of basic models of etiology and pathogenesis * Complete catalog of autoantibodies produced * Includes an outstanding review of imaging techniques for the diagnosis of lupus and its complications for each organ system * Includes CD-ROM of images excellent for teaching purposes and downloading into presentations

Systemic Lupus Erythematosus E-Book

Systemic Lupus Erythematosus E-Book
  • Author : George Tsokos,Caroline Gordon,Josef S. Smolen
  • Publisher :Unknown
  • Release Date :2007-02-23
  • Total pages :608
  • ISBN : 9780323070874
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Summary : This new companion to Hochberg et al.'s Rheumatology masterwork provides new insights into the causes, detection and therapy of this challenging disease. In this state-of-the-art resource, you'll find ‘one stop' coverage of all the latest scientific and clinical developments in SLE: new concepts in epidemiology, disease activity measures and outcomes; new concepts in immunoregulation, genetic and pathogenic mechanisms; new understanding and novel presentation of the processes of tissue/organ damage; comprehensive coverage of clinical features; and the very latest concepts in treatment. Provides the very latest understanding of the pathogenesis of SLE. Distills current understanding of the cellular, molecular, genetic and environmental factors that instigate and drive the disease. Includes comprehensive coverage of clinical features, including fatigue, organ system manifestations, overlap syndromes, infections, and more. Conveys the very latest understanding of mechanisms of tissue damage, including immune complexes, antibodies, and other mechanisms that lead to organ damage. Contains expert discussion of processes that are responsible for tissue injury - a hallmark of this text. Incorporates the latest treatment modalities, including steroids and non-steroidals, cytotoxic drug treatment, PAP's, and therapies on the horizon. Discusses the latest treatment options on disease modifying or disease controlling agents.

Dubois' Lupus Erythematosus and Related Syndromes E-Book

Dubois' Lupus Erythematosus and Related Syndromes E-Book
  • Author : Daniel Wallace,Bevra Hannahs Hahn
  • Publisher :Unknown
  • Release Date :2012-09-27
  • Total pages :608
  • ISBN : 9781455728176
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Summary : Recognized for more than 45 years as the definitive text in the field, Dubois’ Lupus Erythematosus and Related Syndromes strikes the perfect balance between basic science and clinical expertise, providing the evidence-based findings, treatment consensuses, and practical clinical information you need to confidently diagnose and manage SLE. Broaden your understanding with comprehensive coverage of every aspect of cutaneous and systemic lupus erythematosus, including definitions, pathogenesis, autoantibodies, clinical and laboratory features, management, prognosis, and patient education. Experience clinical scenarios with vivid clarity through a heavily illustrated, full-color format which includes fundamental images of lupus rashes as well as graphs, algorithms, and differential diagnosis comparisons. Discover the latest in systemic lupus erythematosus with new chapters on important emerging topics such as socioeconomic and disability aspects; and rigorously updated chapters that include expanded coverage of the nervous system, and the most in-depth discussion of immunity and regulatory cells. Learn from the very best. World-renowned rheumatologists Drs. Daniel Wallace and Bevra Hannahs Hahn, along with new associate editors Drs. Michael Weisman, Ronald Van Vollenhoven, Nan Shen, and David Isenberg, present definitive coverage on new and rapidly changing areas in the field. Rely on it anytime, anywhere! Access the full text, image bank, and bonus online-only chapters at www.expertconsult.com. Dubois’ Lupus Erythematosus was first published in 1966. For the past forty years, the product has distinguished itself internationally as the go-to reference on lupus and related diseases. For rheumatologists and internal medicine practitioners who need a comprehensive clinical reference on systemic lupus erythematosus (SLE) and related disorders, this product delivers a complete arsenal of information on SLE, connective tissue diseases, and the antiphospholipid syndromes.

Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
  • Author : Caroline Gordon,David Isenberg
  • Publisher :Unknown
  • Release Date :2016-03-10
  • Total pages :160
  • ISBN : 9780198739180
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Summary : Systemic Lupus Erythematosus (often abbreviated to SLE or lupus) is a systemic autoimmune disease that can affect any part of the body, causing the immune system to attack the body's cells and tissue, and resulting in inflammation and tissue damage. This new addition to the Oxford Rheumatology Library series provides a practical approach to the assessment and management of patients with this complex, multisystem autoimmune disease to improve the diagnosis and treatment of the disease and its complications. It provides comprehensive but easy to assimilate reading for consultant rheumatologists, dermatologists, nephrologists, obstetricians and other specialists and their trainees, interested GPs, specialist nurses, and clinical trial teams both in hospitals and contract research organizations.

Fulminant Systemic Vasculitis in Systemic Lupus Erythematosus. Case Report and Review of the Literature

Fulminant Systemic Vasculitis in Systemic Lupus Erythematosus. Case Report and Review of the Literature
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2014
  • Total pages :229
  • ISBN : OCLC:1051397209
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Summary : Vasculitis in systemic lupus erythematosus (SLE) has a broad spectrum of clinical manifestations from cutaneous to visceral involvement and its prognosis ranges from mild to life-threatening. We report the case of a previously healthy 17-year-old woman with eight months' history of arthralgias and myalgias. Subsequently, she developed facial and lower limbs edema, and hair loss. Two weeks before admission to a secondary level hospital, she developed fever up to 40 °C followed by abdominal pain, rectal bleeding, hematemesis and blisters on both legs, reason for which she was hospitalized. With active bullous SLE with rapidly progressive glomerulonephritis suspected, she was treated with methylprednisolone pulses without response. After one week of treatment, she was transferred to a tertiary level hospital. On admission she presented acute arterial insufficiency of the lower extremities, respiratory failure with apnea, metabolic acidosis and shock; six hours later she died. Autopsy findings showed active diffuse lupus nephritis and diffuse systemic vasculitis that involved vessels from the skin, brain, myocardium, spleen, iliac and renal arteries. In addition, serositis of the small intestine and colon, acute and chronic pericarditis, pericardial effusion and myocarditis were found. Immunologic tests confirmed SLE diagnosis. In this case the fulminant course was the result of SLE high disease activity, visceral vasculitis of several organs and late diagnosis, referral and treatment. Early diagnosis, and opportune referral to the rheumatologist for intensive treatment can improve the outlook in these patients.

Neuropsychiatric Systemic Lupus Erythematosus

Neuropsychiatric Systemic Lupus Erythematosus
  • Author : Shunsei Hirohata
  • Publisher :Unknown
  • Release Date :2018-04-03
  • Total pages :189
  • ISBN : 9783319764962
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Summary : Neuropsychiatric manifestation in systemic lupus erythematosus (NPSLE) is one of the most recalcitrant complications of the disease. According to the 1999 ACR nomenclature and case definitions, diffuse psychiatric/neuropsychological syndromes in NPSLE (anxiety disorder, acute confusional state, cognitive dysfunction, mood disorder, psychosis) (diffuse NPSLE) present psychiatric manifestations unlike neurologic syndromes (focal NPSLE) originating from focal CNS lesions, such as cerebrovascular disease, demyelinating syndrome, headache, aseptic meningitis, chorea, seizures and myelopathy. A number of studies have reported that diffuse NPSLE is usually associated with the presence of autoantibodies against neuronal cells in serum as well as in cerebrospinal fluid (CSF). Moreover, IL-6 has been shown to be elevated in CSF of patients with diffuse NPSLE. Recently, it has been demonstrated that the severity of blood-brain barrier damages plays a crucial role in the development of acute confusional state, the severest form of diffuse NPSLE through the accelerated entry of larger amounts of autoantibodies to NMDA receptor subunit NR2 into the CNS. Since the importance of autoantibodies in the NPSLE has been now evident, such an aggressive treatment, especially B cell depleting therapy, would make sense in that it would reduce the levels of pathogenic autoantibodies, leading to a better prognosis of NPSLE. As far as we know, no single book specifically dedicated to NPSLE alone has been published as yet. As mentioned above, NPSLE constitutes a vastly expanding field of research with increasing numbers of papers published annually. Therefore, we believe that an effort to collect and critically review these publications is invaluable. Such an effort will provide an important contribution to basic researchers as well as clinicians working in the field of neurology, rheumatology, psychiatry and internal medicine fields.

Type 1 Interferon Related Genes and Systemic Lupus Erythematosus (SLE)

Type 1 Interferon Related Genes and Systemic Lupus Erythematosus (SLE)
  • Author : Loza Jumeea Al-Muttaniyah
  • Publisher :Unknown
  • Release Date :2018
  • Total pages :182
  • ISBN : OCLC:1191422804
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Summary :

Advanced Handbook of Systemic Lupus Erythematosus

Advanced Handbook of Systemic Lupus Erythematosus
  • Author : Laurent Arnaud,Ronald van Vollenhoven
  • Publisher :Unknown
  • Release Date :2017-09-10
  • Total pages :167
  • ISBN : 9783319430355
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Summary : This book will provide an introduction to the epidemiology, etiology and pathogenesis of the condition while also exploring the classification, diagnosis, and current and emerging therapies for systemic lupus erythematosus. Systemic lupus erythematosus is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue. It can affect the skin, joints, kidneys, brain, and other organs. The underlying cause of the disease is not fully known, and SLE is much more common in women than in men. It may occur at any age but most often occurs in people between 10 and 50 years of age. This is the second Adis title from Ronald F van Vollenhoven, who previously authored Biologics for the Treatment of Rheumatoid Arthritis.

Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
  • Author : Josef S. Smolen,Christoph C. Zielinski
  • Publisher :Unknown
  • Release Date :2012-12-06
  • Total pages :358
  • ISBN : 9783642716423
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Summary : More than 140 years ago, lupus erythematosus (LE) was recognized as a disease entity by clinicians working in the field of dermatology, which had only recently become an independent medical discipline. Soon after cutaneous lupus was first reported, it was realized that, apart from the skin, the disease could involve other organs and thus be systemic in nature. The latter observations were first made by MORITZ KApOSI [1], whose work has attracted renewed attention re cently and who succeeded FERDINAND VON HEBRA to the chair of dermatology at the Medical Faculty in Vienna. The early description of lupus erythematosus in both its cutaneous and systemic manifes tations was thus intimately associated with Vienna and its Medical School. The next phase in the study of lupus was characterized by an in crease in knowledge of the type and extent of organ involvement. The work by OSLER [2], LIBMANN and SACKS [3], and KLEMPERER [4] best represents these advances. The increase in clinical knowledge of LE finally led to DUBOIS' famous monograph [5], which was pub lished at a time of renewed interest in SLE, elicited by the descrip tion by HARGRAVES et al. [6] of the LE-cell phenomenon. A more detailed analysis of this finding revealed that the disease was charac terized by an abnormal immune response, although its pathogenetic implications were still unclear.

Cecil Textbook of Medicine

Cecil Textbook of Medicine
  • Author : Russell La Fayette Cecil
  • Publisher :Unknown
  • Release Date :2004
  • Total pages :2506
  • ISBN : 9997638166
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Summary :

Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :1975
  • Total pages :199
  • ISBN : OCLC:488663679
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Summary :

Oxford Textbook of Rheumatology

Oxford Textbook of Rheumatology
  • Author : Richard A Watts,Philip Conaghan,Chris Denton,Helen Foster,John Isaacs,Ulf Müller-Ladner
  • Publisher :Unknown
  • Release Date :2013-10
  • Total pages :1522
  • ISBN : 9780199642489
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Summary : This fourth edition of the Oxford Textbook of Rheumatology provides a complete overview of all rheumatological and musculoskeletal problems, and is a comprehensive reference for all trainees and specialists in the field.

Kelley's Textbook of Rheumatology

Kelley's Textbook of Rheumatology
  • Author : Shaun Ruddy,Ralph C. Budd
  • Publisher :Unknown
  • Release Date :2005
  • Total pages :1916
  • ISBN : 0721609317
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Summary : Purchasing this product will provide you with a PINCODE providing access to the fully searchable website, www.kelleysrheum.com. On this site you will find the full contents of the 2-volume set fully searchable and UPDATED WEEKLY, image library available for downloads to enhance your presentations, and board review questions. DVD-ROM PLUS access to entire contents online - fully searchable. Weekly content updates. Direct links to PubMed. Over 200 additional 4-color images NOT in the book. Image library for PowerPoint downloads includes ALL images. Self-assessment questions for Board review. Features new chapters on: Antigen Presenting Cells Synoviocytes Chondrocytes Signal Transduction in Rheumatic Diseases Recruitment of Cells and Angiogenesis Economic Burden of Rheumatic Diseases Education of Patients Anti-Cytokine Therapies Familial Auto-Inflammatory Syndromes. Explores hot topics such as: Pediatric Rheumatology Antiphospholipid antibody syndrome SLE The complex roles of cytokines in normal immunity and rheumatic disease The pathogenesis of rheumatoid arthritis. Includes a bound-in DVD, featuring over an HOUR of video clips of the musculoskeletal examination, abnormal arthroscopic findings, complete image library, and over 300 self-assessment questions for Board review. Purchase of this product includes a limited personal license for use exclusively by the individual who has purchased the product. This license and access to the web site operates strictly on the basis of a single user per PIN. The sharing of passwords is strictly prohibited, and any attempt to do so will invalidate the password. The license and access may not be lent, resold, or otherwise circulated. Full details of the license and terms and conditions of use are available upon registration. Your purchase of the Kelley's Textbook of Rheumatology Online, 7th Edition entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. If the next edition is published less than one year after your purchase, you will be entitled to online access for one year from your date of purchase. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should online access to the web site be discontinued.

Autoimmune Bullous Diseases

Autoimmune Bullous Diseases
  • Author : Müzeyyen Gönül,Seray Çakmak
  • Publisher :Unknown
  • Release Date :2018-05-09
  • Total pages :256
  • ISBN : 9781789230260
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Summary : Autoimmune bullous diseases are a group of rare skin diseases characterized by intraepidermal and subepidermal bullae formations due to autoantibodies directed against the structural proteins of the epidermis or the dermal-epidermal junction. Early and correct diagnosis and adequate treatment of autoimmune bullous diseases are important as they cause morbidity and mortality in the affected patients. This book, which gives detailed information about autoimmune bullous diseases, has two sections and nine chapters with sixteen contributing authors. The first section describes the structure and tasks of desmosomes and basement membrane zone, which consist of the major antigens of skin integrity targeted by autoantibodies. The second section is about the epidemiology, etiopathogenesis, mucocutaneous, histopathologic and laboratory findings, and therapy of autoimmune bullous diseases.

Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
  • Author : Naomi F. Rothfield
  • Publisher :Unknown
  • Release Date :1975
  • Total pages :7
  • ISBN : OCLC:920250087
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Summary :

Neuropsychiatric Features of Medical Disorders

Neuropsychiatric Features of Medical Disorders
  • Author : James W. Jefferson
  • Publisher :Unknown
  • Release Date :2012-12-06
  • Total pages :383
  • ISBN : 9781468439205
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Summary : When Critical Issues in Psychiatry was conceived, there were several sub jects I considered to be of crucial importance in a series devoted to residents and clinicians in psychiatry, as well as to other mental health professionals. Of prominence was the pressing need for an in-depth and scholarly exam ination of the interface between medicine and psychiatry. I had been amazed to find that not a single book, to my mind, adequately addressed the psy chological symptoms and manifestations of both common and rare medical illness. It seemed to me that there was a need for a work which would achieve the following goals: First, it would assist in the differential diagnosis of functional psychiatric symptoms versus symptoms secondary to recog nized or unrecognized medical illness; second, it would elucidate the psy chological symptoms resulting from pharmacologic and other therapeutic interventions in medical illness; and third, it would examine the use of psychopharmacological agents in the presence of medical illness and the drugs used to treat that illness. Dr. Jefferson is Board Certified in both internal medicine and psychiatry, and both Drs. Jefferson and Marshall have extensive clinical experience from their many years of consultation/liaison work in psychiatry. Their experience and expertise have resulted in what I believe to be a monumental contri bution to the literature.

Plasma C4d as Marker for Lupus Nephritis in Systemic Lupus Erythematosus

Plasma C4d as Marker for Lupus Nephritis in Systemic Lupus Erythematosus
  • Author : Anonim
  • Publisher :Unknown
  • Release Date :2017
  • Total pages :229
  • ISBN : OCLC:1052092220
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Summary :

Lupus Erythematosus

Lupus Erythematosus
  • Author : Peter H. Schur,Elena M. Massarotti
  • Publisher :Unknown
  • Release Date :2012-07-06
  • Total pages :260
  • ISBN : 9781461411895
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Summary : Often considered the prototypic autoimmune disease, Lupus is characterized by protean manifestations and affects a wide range of organ systems. Despite widespread availability of anti nuclear antibody testing and other technological diagnostic advances, the diagnosis of lupus can be elusive, difficult, and inexact. Treatment of the disease can also be challenging. Advances in immunology and biotechnology have led to a burgeoning world of new therapies in development that offer patients the real possibility of new therapies and physicians and scientists novel insights into the pathogenesis of this complicated immunological disease. Lupus Erythematosus: Clinical Evaluation and Treatment summarizes the clinical aspects of lupus facing the general clinician in the 21st century. In this invaluable, practical book, the reader will find introductory chapters regarding general diagnostic and treatment principles, followed by chapters addressing the lupus-specific organ manifestations. Special topics regarding pregnancy and comorbidities are also presented. Written by highly experienced physicians with special expertise in lupus, Lupus Erythematosus: Clinical Evaluation and Treatment is an indispensable reference for the common and not so common problems affecting patients with lupus.

Pregnancy Thrombophilia

Pregnancy Thrombophilia
  • Author : Petar Ivanov
  • Publisher :Unknown
  • Release Date :2013-09-19
  • Total pages :168
  • ISBN : 9789535111993
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Summary : Learn the recent statements concerning the impact and management of mother-fetal thrombophilia, the achievement necessary for gestation complication prevention and realizing a successful pregnancy valuation. Pregnancy Thrombophilia - The Unsuspected Risk encompasses complete many-sides aspects of thrombophilic conditions during pregnancy, including clinical and basic knowledge approach faced to: 1) Obstetricians, IVF involving gynecologists, Internists, and General practitioners, especially skilled in high risk pregnancy assessment will receive up to date evidence for mother thrombophilia testing indications, an incoming pharmacogenetic approach of individualized antithrombotic therapy and thrombotic tendency management in assisted reproductive technics; 2) Physicians, in particular geneticists, biologists and all researchers, who combine the science of the laboratory with teaching practice, will have essential benefits from the chapters of physiology, pathological and molecular basis of maternal/fetus thrombophilia; 3) The mother-health incorporated immunologists will find a new therapeutic approach beyond anticoagulant treatment in pregnancy with autoimmune conditions. Pregnancy Thrombophilia - The Unsuspected Risk gives you a chance to a rapid review of the recent stands, concerning maternal thrombotic state and authoritative and easy to read summary answers in your daily pregnancy follow up practice.

The Clinical Management of Systemic Lupus Erythematosus

The Clinical Management of Systemic Lupus Erythematosus
  • Author : Peter H. Schur
  • Publisher :Unknown
  • Release Date :1996
  • Total pages :281
  • ISBN : UOM:39015038550375
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Summary : This volume is designed to provide clinicians with practical guidance on the diagnosis and management of systemic lupus erythematosus. Revised and updated to reflect diagnostic and therapeutic advances, the book offers advice on the day-to-day care of patients with the varied manifestations of this disease.

Systemic Autoimmunity

Systemic Autoimmunity
  • Author : P. E. Bigazzi
  • Publisher :Unknown
  • Release Date :1991-08-30
  • Total pages :320
  • ISBN : 0824785509
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Summary : Surveys the biotechnologically influenced advances in the understanding of systemic autoimmune disorders, highlighting recent research using cell biology and biochemistry, the cloning of immune cells, recombinant DNA, and molecular genetics. Among the topics are the role of complement in inflammatio