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Tailor-Made Polysaccharides in Drug Delivery

Tailor-Made Polysaccharides in Drug Delivery
  • Author : Amit Kumar Nayak,Md Saquib Hasnain
  • Publisher :Unknown
  • Release Date :2021-02-15
  • Total pages :370
  • ISBN : 0128212861
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Summary : Tailor-Made Polysaccharides in Drug Delivery provides extensive details on all the vital precepts, basics and fundamental aspects of tailored polysaccharides in the pharmaceutical and biotechnological industry for understanding and developing high quality products. The book offers a comprehensive resource to understand the potential of the materials in forming new drug delivery methods. It will be useful to pharmaceutical scientists, chemical engineers, and regulatory scientists and students actively involved in pharmaceutical product and process development of tailored-made polysaccharides in drug delivery applications. The utilization of natural polymeric excipients in numerous healthcare applications demand the replacement of the synthetic polymers with the natural ones due to their biocompatibility, biodegradability, economic extraction and readily availability. The reality behind the rise in importance of these natural materials is that these sources are renewable if grown in a sustainable means and they can tender incessant supply of raw materials. Amongst these natural polymers, polysaccharides are considered as excellent excipients because of its non-toxic, stable, biodegradable properties. Several research innovations have been made on applications of polysaccharides in drug delivery. Provides methodologies for the design, development and selection of tailor-made, natural polysaccharides in drug delivery for particular therapeutic applications Includes illustrations that demonstrate the mechanism of biological interaction of tailor-made polysaccharides Discusses the regulatory aspects and demonstrates the clinical efficacy of tailor-made polysaccharides

Tailor-Made Polysaccharides in Biomedical Applications

Tailor-Made Polysaccharides in Biomedical Applications
  • Author : Amit Kumar Nayak,Md Saquib Hasnain,Tejraj M. Aminabhavi
  • Publisher :Unknown
  • Release Date :2021-02-15
  • Total pages :358
  • ISBN : 9780128213568
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Summary : Tailor-Made Polysaccharides in Biomedical Applications provides extensive details on all the vital precepts, basics, and fundamental aspects of tailored polysaccharides in the pharmaceutical and biotechnological industries. This information provides readers with the foundation for understanding and developing high-quality products. The utilization of natural polymeric excipients in numerous healthcare applications demands the replacement of the synthetic polymers with natural polymers. Natural polymers are superior in terms of biocompatibility, biodegradability, economic extraction, and ready availability. Natural polymers are especially useful in that they are a renewable source of raw materials, as long as they are grown sustainably. Among these natural polymers, polysaccharides are considered as excellent excipients because they are nontoxic, stable, and biodegradable. Several research innovations have been carried out using polysaccharides in drug delivery applications. This book offers a comprehensive resource to understand the potential of these materials in forming new drug delivery methods. It will be useful to biomedical researchers, chemical engineers, regulatory scientists, and students who are actively involved in developing pharmaceutical products for biomedical applications by using tailor-made polysaccharides. Provides methodology for the design, development, and selection of tailor-made polysaccharides in biomedical applications, including for particular therapeutic applications Includes illustrations demonstrating the mechanism of biological interaction of tailor-made polysaccharides Discusses the regulatory aspects and demonstrates the clinical efficacy of tailor-made polysaccharides

Natural Polysaccharides in Drug Delivery and Biomedical Applications

Natural Polysaccharides in Drug Delivery and Biomedical Applications
  • Author : Md Saquib Hasnain,Amit Kumar Nayak
  • Publisher :Unknown
  • Release Date :2019-07-23
  • Total pages :654
  • ISBN : 9780128170564
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Summary : Natural Polysaccharides in Drug Delivery and Biomedical Applications provides a fundamental overview of natural polysaccharides, their sources, extraction methodologies, and characterizations. It covers specific natural polysaccharides and their effective application in drug delivery and biomedical use. Additionally, chapters in the book discuss key topics including the sources and extraction methodologies of natural polysaccharides, their role in tissue engineering applications, polysaccharide-based nanoparticles in biomedical applications, and their role in the delivery of anticancer drugs. Written by industry leaders and edited by experts, this book emphasizes recent advances made in the field. Natural Polysaccharides in Drug Delivery and Biomedical Applications provides academics, researchers, and pharmaceutical health care professionals with a comprehensive book on polysaccharides in pharmaceutical delivery process. Provides fundamental concepts of natural polysaccharides as it applies to the pharmaceutical, biomedical, and biotechnology industries Includes contributions from global leaders and experts from academia, industry, and regulatory agencies in the application of natural polysaccharides in pharmaceutical products and biomedical utilization Offers practical examples, illustrations, chemical structures, and research case studies to help explain natural polysaccharides concepts in drug delivery and biomedical applications

Polysaccharide Carriers for Drug Delivery

Polysaccharide Carriers for Drug Delivery
  • Author : Sabyasachi Maiti,Sougata Jana
  • Publisher :Unknown
  • Release Date :2019-06-14
  • Total pages :802
  • ISBN : 9780081025543
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Summary : Polysaccharide Carriers for Drug Delivery presents the latest information on the selection of safe materials. Due to reported safety profiles on polysaccharides; they have been the natural choice for investigation. A wide variety of drug delivery and biomedical systems have been studied, however, the related information either concept-wise or application-oriented is scattered, therefore becoming difficult for readers and researchers to digest in a concise manner. This gathering of information will help readers easily comprehend the subject matter. Focuses on biopolysaccharide-based, distinct approaches for drug delivery applications Illustrates new concepts and highlights future scope for clinical development Provides comprehensive, up-to-date information on different aspects of drug delivery technology

Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications

Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications
  • Author : Abdel Salam Hamdy Makhlouf,Nedal Y. Abu-Thabit
  • Publisher :Unknown
  • Release Date :2018-06-14
  • Total pages :692
  • ISBN : 9780081019986
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Summary : Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications, Volume One: Types and Triggers discusses, in detail, the recent trends in designing biodegradable and biocompatible single-responsive polymers and nanoparticles for safe drug delivery. Focusing on the most advanced materials and technologies, evaluation methods, and advanced synthesis techniques stimuli-responsive polymers, the book is an essential reference for scientists with an interest in drug delivery vehicles. Sections focus on innovation, development and the increased global demand for biodegradable and biocompatible responsive polymers and nanoparticles for safe drug delivery. Offers an in-depth look at the basic and fundamental aspects of alternative stimuli-responsive polymers, mechanisms, structure, synthesis and properties Provides a well-defined categorization for stimuli-responsive polymers for drug delivery based on different triggering mechanisms Discusses novel approaches and challenges for scaling up and commercialization of stimuli-responsive polymers

Polysaccharides in Advanced Drug Delivery

Polysaccharides in Advanced Drug Delivery
  • Author : Akhilesh Vikram Singh,Bang-Jing Li
  • Publisher :Unknown
  • Release Date :2020-03-24
  • Total pages :198
  • ISBN : 9781000050868
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Summary : This book contains selective chapters from eminent experts working in the interdisciplinary arena of material science and its use in drug delivery. From their recent research experience, the readers can achieve a wide vision on the new and ongoing potentialities of polysaccharides and its application in the field of advanced drug delivery. This book contains selective polymers that were recently explored in the field of drug delivery such as starch, konjac, chitosan, alginate and other natural polymers originated from sea. It also has one chapter exclusively on nanotechnology that explains multifaceted application of natural polymer in the field of advanced drug delivery. Note: T& F does not sell or distribute the Hardback in India, Pakistan, Nepal, Bhutan, Bangladesh and Sri Lanka.

Functional Polysaccharides for Biomedical Applications

Functional Polysaccharides for Biomedical Applications
  • Author : Sabyasachi Maiti,Sougata Jana
  • Publisher :Unknown
  • Release Date :2019-06-11
  • Total pages :526
  • ISBN : 9780081025567
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Summary : Functional Polysaccharides for Biomedical Applications examines the fundamentals and properties of these natural materials and their potential biomedical applications. With an emphasis on therapeutic and sensing applications, the book also reviews how polysaccharides can be modified for tissue engineering applications. Sections discuss the basics of polysaccharides, give an overview of the potential applications, look at novel materials and technologies for use in tissue regeneration and therapeutics, and detail current biomedical applications. With a strong focus on materials, engineering and applications, this book is a valuable resource for those with an interest in harnessing the biomedical potential of natural polymers. Describes strategies for developing polysaccharides-based biomedical devices Illustrates concepts and encompasses scope for clinical development Provides advanced and comprehensive information on biomedical constructs

Polysaccharide based Nano-Biocarrier in Drug Delivery

Polysaccharide based Nano-Biocarrier in Drug Delivery
  • Author : Tapan Kumar Giri,Bijaya Ghosh
  • Publisher :Unknown
  • Release Date :2018-09-03
  • Total pages :368
  • ISBN : 9780429830662
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Summary : This book discusses various fundamental aspects of polysaccharide based nano-biocarrier drug delivery systems and its application in the delivery of small molecules, proteins, peptides, oligonucleotides and genes. It also discusses advances in drug delivery systems in treatment of cancer, cardiovascular, pulmonary, and infectious diseases.

Biopolymer-Based Nanomaterials in Drug Delivery and Biomedical Applications

Biopolymer-Based Nanomaterials in Drug Delivery and Biomedical Applications
  • Author : Hriday Bera,Chowdhury Mobaswar Hossain,Sudipta Saha
  • Publisher :Unknown
  • Release Date :2021-01-18
  • Total pages :628
  • ISBN : 9780128208755
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Summary : Biopolymer-Based Nanomaterials in Drug Delivery and Biomedical Applications presents a clear and detailed body of information on biopolymer chemistry and polymer sciences in drug delivery. The book covers the recently reported nanomaterials consisting of biopolymers such as polysaccharides (i.e., plant, animal, bacteria, algae and fungi-derived) and proteins in terms of their structures, synthetic protocols and characterizations. In addition, their applications as therapeutic drug and gene delivery carriers and in other biomedical fields are reviewed. This book compiles chapters contributed by internationally renowned scholars working in biopolymer-based nanomaterials, offering a wide vision on the new and ongoing potential of different biopolymeric nanomaterials. The information related to concepts, design protocols and applications of biopolymer-based nanoplatforms is presented here, with detailed chapters on Pectin based nanomaterials, Konjac glucomannan based nanomaterials, Guar gum-based nanomaterials, tailor-made gum Arabic based nanomaterials, among others. Such systems are widely being used as functional materials for drug delivery and other therapeutic applications. Provides a critical and detailed examination in the recent development of biopolymer-based nanomaterials Focuses on modified biopolymer-based, diverse cutting-edge techniques in drug delivery and biomedical applications Assesses the opportunities and challenges of biopolymer-based nano-carriers in pharmaceutical and biomedical fields

Nanomaterials for Drug Delivery and Therapy

Nanomaterials for Drug Delivery and Therapy
  • Author : Alexandru Mihai Grumezescu
  • Publisher :Unknown
  • Release Date :2019-03-14
  • Total pages :580
  • ISBN : 9780128166291
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Summary : Nanomaterials for Drug Delivery and Therapy presents recent advances in the field of nanobiomaterials and their important applications in drug delivery, therapy and engineering. The book offers pharmaceutical perspectives, exploring the development of nanobiomaterials and their interaction with the human body. Chapters show how nanomaterials are used in treatments, including neurology, dentistry and cancer therapy. Authored by a range of contributors from global institutions, this book offers a broad, international perspective on how nanotechnology-based advances are leading to novel drug delivery and treatment solutions. It is a valuable research resource that will help both practicing medics and researchers in pharmaceutical science and nanomedicine learn more on how nanotechnology is improving treatments. Assesses the opportunities and challenges of nanotechnology-based drug delivery systems Explores how nanotechnology is being used to create more efficient drug delivery systems Discusses which nanomaterials make the best drug carriers

Alginates in Drug Delivery

Alginates in Drug Delivery
  • Author : Amit Kumar Nayak,MD Saquib Hasnain
  • Publisher :Unknown
  • Release Date :2020-02-15
  • Total pages :312
  • ISBN : 0128176407
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Summary : Alginates in Drug Delivery explores the vital precepts, basic and fundamental aspects of alginates in pharmaceutical sciences, biopharmacology, and the biotechnology industry in extensive detail to understand the field and develop high quality products. The use of natural polymers in healthcare applications over synthetic polymers is becoming more prevalent due to natural polymers' biocompatibility, biodegradability, economic extraction and ready availability. These natural materials are renewable if grown sustainably, and they can tender incessant supply of raw materials. Amongst these natural polymers, Alginates are considered excellent excipients because of their non-toxic, stable and biodegradable properties, and can be used in a variety of applications in pharmaceuticals, medical diagnostic aids and material science. Several innovations have been made on applications of alginate in drug delivery and biomedicines including in liquid gels, powders, beads, films, tablets, capsules, microspheres, microparticles, nanoparticles, nanosponges, nanofibrils and nanocomposites. To fully utilize and harness the potential of alginates, a thorough understanding of the synthesis, purification, and characterization of alginates and their derivatives needs to be is needed. This book collects in a single volume all relevant information on alginates in health care including recent advances in the field. Alginates in Drug Delivery is a highly useful resource for pharmaceutical scientists, health care professionals and regulatory scientists actively involved in pharmaceutical product and process development of natural polymer containing drug delivery, as well as postgraduate students and postdoctoral research fellows in pharmaceutical sciences. Provides a single source examining the complete alginate chemistry, collection, chemical modifications, characterization and applications in healthcare fields Includes high quality illustrations along with practical examples and research case studies Contains contributions by global leaders and experts from academia, industry and regulatory agencies, who are pioneers in the application of natural polysaccharides in diverse pharmaceutical fields

Polysaccharide Materials

Polysaccharide Materials
  • Author : Kevin Edgar,Thomas Heinze,Charles Buchanan
  • Publisher :Unknown
  • Release Date :2009
  • Total pages :292
  • ISBN : UOM:39015075691025
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Summary : Today we are experiencing a renaissance in the chemistry of polysaccharide materials. This is due in part to recognition of the importance of renewable-based materials in a society in which petroleum has become a much more expensive feedstock, with a cloudy future with respect to adequacy of supply. There are currently intense, global efforts to develop a biomass-based refinery process, intended to produce biofuel (ethanol or butanol being the top candidates) that will replace some or all of the petroleum-based fuel we now use. In parallel, scientists and non-scientists have become aware of the opportunities that this biofuel industry will create for biomass-based products. The utilization of waste from the biofuel process, along with the exploitation of the collection system for biomass that will serve the biofuel production process, to make other products from biomass, will create an unprecedented and revolutionary opportunity for the creation of integrated biorefineries. These biorefineries will have substantial resemblance to current petroleum refineries, in that they will convert a natural product (or more properly, products) into fuel by chemical transformations and separation processes, and simultaneously use co-products and main products as feedstocks for the production of more complex chemicals. In order to take advantage of the opportunities presented by a biorefinery-based economy, it is crucial that we develop new synthetic methods for polysaccharide derivatives, and new understanding of the structure-property-performance relationships of these versatile molecules. This symposium series book will describe new synthetic methods, novel polysaccharide derivatives, new applications of these derivatives in biomedicine and packaging applications, and numerous examples of the creation of new insight into the design of polysaccharide materials for performance. The articles in this symposium series book are good examples of the advances in polysaccharide chemistry being made in the current renaissance that will help to move us towards a biorefinery future.

Biopolymer-Based Composites

Biopolymer-Based Composites
  • Author : Sougata Jana,Sabyasachi Maiti,Subrata Jana
  • Publisher :Unknown
  • Release Date :2017-06-15
  • Total pages :422
  • ISBN : 9780081019153
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Summary : Biopolymer-Based Composites: Drug Delivery and Biomedical Applications presents a comprehensive review on recent developments in biopolymer-based composites and their use in drug delivery and biomedical applications. The information contained in this book is critical for the more efficient use of composites, as detailed up-to-date information is a pre-requirement. The information provided brings cutting-edge developments to the attention of young investigators to encourage further advances in the field of bio-composite research. Currently, biopolymers are being investigated for the design of various drug delivery and biomedical devices due to their non-toxic, biodegradable and biocompatible nature. Mostly, biopolymer-based solid orals, gels, hydrogel beads, and transdermal matrices have been designed in order to control drug/protein release in simulated bio-fluids. Presents the most updated information in the field of pharmaceutical and biological sciences Contains color figures and illustrations to help users understand key topics Useful guide for young researchers working towards new innovations Includes chapters covered by eminent scientists in the field

Biological Activities and Application of Marine Polysaccharides

Biological Activities and Application of Marine Polysaccharides
  • Author : Emad Shalaby
  • Publisher :Unknown
  • Release Date :2017-01-11
  • Total pages :328
  • ISBN : 9789535128595
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Summary : Marine organisms have been under research for the last decades as a source for different active compounds with various biological activities and application in agriculture, pharmacy, medicine, environment, and industries. Marine polysaccharides from these active compounds are used as antibacterial, antiviral, antioxidant, anti-inflammation, bioremediations, etc. During the last three decades, several important factors that control the production of phytoplankton polysaccharides have been identified such as chemical concentrations, temperature, light, etc. The current book includes 14 chapters contributed by experts around the world; the chapters are categorized into three sections: Marine Polysaccharides and Agriculture, Marine Polysaccharides and Biological Activities, and Marine Polysaccharides and Industries.

Drug Delivery in Oncology

Drug Delivery in Oncology
  • Author : Felix Kratz,Peter Senter,Henning Steinhagen
  • Publisher :Unknown
  • Release Date :2013-09-30
  • Total pages :1822
  • ISBN : 9783527647750
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Summary : In this first authoritative overview on modern cancer chemotherapy 121 international specialists have contributed their experience and recent data for what is likely to become the gold standard in the field. The authors summarize knowledge gained over the past decade, from basic concepts to successful applications in the clinic, covering active and passive targeting strategies as well as tissue-specific approaches. All current and future targeted delivery systems are discussed, from ligand-based to antibody-based polymer-based systems, right up to micro- and nanoparticulate systems. A special section covers the delivery of nucleic acid therapeutics, such as siRNA, miRNA and antisense nucleotides. In each case, a description of the basic technique is followed by a discussion of the latest preclinical and clinical developments in the field. By virtue of its clear and didactic structure, rich illustrative material and summary chapters, this handbook and ready reference enables the efficient transfer of knowledge between different disciplines, from basic research to the clinician and vice versa. It is equally well suited for professionals, researchers and students in medical oncology and cancer biology, and is also excellent for teaching medical students the foundations of 21st century cancer chemotherapy.

Polymeric Hydrogels as Smart Biomaterials

Polymeric Hydrogels as Smart Biomaterials
  • Author : Susheel Kalia
  • Publisher :Unknown
  • Release Date :2015-11-18
  • Total pages :234
  • ISBN : 9783319253220
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Summary : This book is concerned with polymeric hydrogels, which are considered as one of the most promising types of new polymer-based materials. Each chapter in this book describes a selected class of polymeric hydrogels, such as superabsorbent hybrid nanohydrogels, conducting polymer hydrogels, polysaccharide-based or protein-based hydrogels, or gels based on synthetic polymers. In this way, the book also addresses some of the fascinating properties and applications of polymeric hydrogels: they are three-dimensional, hydrophilic, polymeric networks that can absorb, swell and retain large quantities of water or aqueous fluids. In combination with metal nanoparticles, nanofibrils or nanowhiskers, which may be embedded in the gels, they find widespread applications, ranging from agriculture, and waste water treatment, over electronics, to pharmaceutical and biomedical applications. Applications mentioned in this book include electro sensors, capacitors, electromechanical actuators, and even artificial muscles.

Microbial Exopolysaccharides: From Genes to Applications

Microbial Exopolysaccharides: From Genes to Applications
  • Author : Jochen Schmid,Julia Fariña,Bernd Rehm,Volker Sieber
  • Publisher :Unknown
  • Release Date :2016-06-24
  • Total pages :229
  • ISBN : 9782889198436
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Summary : Microbial polysaccharides represent an attractive alternative to those from plants or macro algae. They can be produced from renewable sources including lignocellulosic waste streams. Their production does not depend on geographical constraints and/or seasonal limitations. Additionally the manipulation of biosynthetic pathways to enhance productivity or to influence the chemical polysaccharide composition is comparatively easy in bacteria. Microbial exopolysaccharides represents a valuable resource of biogenic and biodegradable polymers, suitable to replace petro based polymers in various technical applications. Furthermore, biocompatible exopolysaccharides are very attractive in medical applications, such as drug delivery systems, use as vaccines or nanoparticles. This research topic will depict the status quo, as well as the future needs in the field of EPS and biofilm research. Starting from the unexplored diversity of microbial polysaccharide producers to production processes and possibilities for modifications, to enhance the already high number of functionalities based on the chemical structures. An overview of the recent and future applications will be given, and the necessity in unravelling the biosynthesis of microbial exopolysaccharide producers is depicted, highlighting the future trend of tailor made polymers. Constraints in structure analysis of these highly complex biogenic polymers are described and different approaches to solve the restrictions in imaging and NMR analysis will be given. Therefore; this research topic comprises the whole process from genes to applications.

Nanoarchitectonics for Smart Delivery and Drug Targeting

Nanoarchitectonics for Smart Delivery and Drug Targeting
  • Author : Alina Maria Holban,Alexandru Mihai Grumezescu
  • Publisher :Unknown
  • Release Date :2016-07-12
  • Total pages :970
  • ISBN : 9780323477222
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Summary : Nanoarchitectonics for Smart Delivery and Drug Targeting is one of the first books on the market to exclusively focus on the topic of nanoarchitectonics, a rapidly developing area of nanotechnology which allows scientists to arrange nanoscale structural units, typically a group of atoms or molecules, in an intended configuration. This book assesses novel applications of nanomaterials in the areas of smart delivery and drug targeting using nanoarchitectonics and discusses the advantages and disadvantages of each application. Provides a scholarly introduction to the uses of nanoarchitectonics in drug delivery and targeting Explores novel opportunities and ideas for developing and improving nanoscale drug delivery systems through the use of nanoarchitectonics, allowing scientists to see how this exciting new technology is used in practice Assesses the pros and cons of each application, allowing readers to assess when it is most appropriate to use nanoarchitectonics in drug delivery

Applications of Nanocomposite Materials in Drug Delivery

Applications of Nanocomposite Materials in Drug Delivery
  • Author : Dr Inamuddin,Abdullah M. Asiri,Ali Mohammad
  • Publisher :Unknown
  • Release Date :2018-06-18
  • Total pages :990
  • ISBN : 9780128137581
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Summary : Applications of Nanocomposite in Drug Delivery discusses and explores the applications of nanocomposites in the area of drug delivery. Starting with a scientific understanding of drug delivery fundamentals, the book explores the utility of nanocomposites in the area of controlled, transdermal, osteo-articular tuberculosis and stimulus sensitive drug delivery applications. The book intricately details and discusses a variety of methods for their preparation, while also highlighting specific applications of nanocomposites in targeted drug delivery. Discusses nanocomposite and nanotechnology for drug delivery Outlines the mechanisms involved in targeted drug delivery using nanocomposites Includes synthesis methods for nanocomposites used in controlled drug delivery Lists various applications of nanocomposites in drug delivery

Seaweed Polysaccharides

Seaweed Polysaccharides
  • Author : Jayachandran Venkatesan,Sukumaran Anil,Se-Kwon Kim
  • Publisher :Unknown
  • Release Date :2017-05-30
  • Total pages :408
  • ISBN : 9780128098172
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Summary : Seaweed Polysaccharides: Isolation, Biological, and Biomedical Applications examines the isolation and characterization of algal biopolymers, including a range of new biological and biomedical applications. In recent years, significant developments have been made in algae-based polymers (commonly called polysaccharides), and in biomedical applications such as drug delivery, wound dressings, and tissue engineering. Demand for algae-based polymers is increasing and represent a potential—very inexpensive—resource for these applications. The structure and chemical modification of algal polymers are covered, as well as the biological properties of these materials – including antithrombic, anti-inflammatory, anticoagulant, and antiviral aspects. Toxicity of algal biopolymers is also covered. Finally, the book introduces and explains real world applications of algal-based biopolymers in biomedical applications, including tissue engineering, drug delivery, and biosensors. This is the first book to cover the extraction techniques, biomedical applications, and the economic perspective of seaweed polysaccharides. It is an essential text for researchers and industry professionals looking to work with this renewable resource. Provides comprehensive coverage of the research currently taking place in biomedical applications of algae biopolymers Includes practical guidance on the isolation, extraction, and characterization of polysaccharides from sustainable marine sources Covers the extraction techniques, biomedical applications, and economic outlook of seaweed polysaccharides

Burger's Medicinal Chemistry and Drug Discovery, Principles and Practice

Burger's Medicinal Chemistry and Drug Discovery, Principles and Practice
  • Author : Alfred Burger,Manfred E. Wolff
  • Publisher :Unknown
  • Release Date :1995-01-02
  • Total pages :1088
  • ISBN : UOM:39015032225875
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Summary : BURGER'S MEDICINAL CHEMISTRY AND DRUG DISCOVERY, FIFTH EDITION, Volume 1: Principles and Practice This new edition of Dr. Alfred Burger's internationally celebrated classic helps researchers acquaint themselves with both traditional and state-of-the-art principles and practices governing new drug research and development. Completely updated and revised to reflect the many monumental changes that have occurred over the past decade and a half in medicinal chemistry and new drug development, this latest edition of Volume 1: Principles and Practice now: * Covers the latest methods of drug discovery, including such "hot" topics as computational chemistry and peptidomimetrics * Has added emphasis on preclinical development issues * Offers the most timely information on a broad range of important regulatory, management, legal, and financial issues * Features in-depth coverage of important factors in the discovery process, including ADME, toxicity and drug allergy, and clinical trials * Updates readers on recent advances in the understanding of the structural biology of drug action * Explores the cutting-edge technologies for drug discovery now in use around the world * Is more than twice the size of its predecessor * Brings together contributions by experts in a wide range of related fields from North America and Europe